AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 30690293 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 24985959 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16083526 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12394229 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 26284906 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21969008 — Biomarker: GCH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCH1; DYT5; GCH
Study 21969008 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21969008 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21969008 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16611656 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 14571611 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 29070768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20977582 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20977582 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20977582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16896999 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16896999 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 10939785 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10939785 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1476285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6727656 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 12021622 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 31262657 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31262657 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 29635252 — Biomarker: PEAR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PEAR1; MEGF12
Study 29635252 — Biomarker: UGT2A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: UGT2A1
Study 24144654 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 24144654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20231521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27816804 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27816804 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 23690341 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7514238 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21933833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20698232 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 7293945 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 12658071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30100295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24809305 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24809305 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 24809305 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14763665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17214336 — Biomarker: TK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TK1
Study 14623542 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 8836901 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 1478292 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 26580489 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26580489 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10429902 — Biomarker: NPL mRNA
Type: Predictive Biomarker (PRD)
Genes: NPL; C1orf13
Study 20824706 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 810765 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26354385 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26051926 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23333143 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 23333143 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 23333143 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 21529841 — Biomarker: NFKB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NFKB1
Study 21529841 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 21529841 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 21529841 — Biomarker: TLR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR5; TIL3
Study 21529841 — Biomarker: IRAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRAK1; IRAK
Study 21529841 — Biomarker: NFKBIA mRNA
Type: Predictive Biomarker (PRD)
Genes: NFKBIA; IKBA; MAD3; NFKBI
Study 15492459 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 11769967 — Biomarker: STAR mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAR; STARD1
Study 30130574 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 27619015 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23922010 — Biomarker: FABP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FABP4
Study 23922010 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 3753363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27737722 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15879332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12649124 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 26956031 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14593351 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14593351 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8999617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6373679 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25335251 — Biomarker: PTN mRNA
Type: Predictive Biomarker (PRD)
Genes: PTN; HBNF1; NEGF1
Study 1574950 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31676258 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31676258 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28870887 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 26401946 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 19278300 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 29037093 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24711481 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24161482 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 11279797 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 27413741 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27413741 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11146577 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8077885 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30543266 — Biomarker: DPT mRNA
Type: Predictive Biomarker (PRD)
Genes: DPT
Study 25175425 — Biomarker: SPINK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPINK1; PSTI
Study 25175425 — Biomarker: ETV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV1; ER81
Study 25175425 — Biomarker: ETV4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV4; E1AF; PEA3
Study 25175425 — Biomarker: ETV5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV5; ERM
Study 21707928 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 18839134 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 18839134 — Biomarker: INSIG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: INSIG2
Study 30031660 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8677636 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8677636 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 20801233 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29214863 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20438378 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28826313 — Biomarker: FSTL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FSTL1; FRP
Study 28826313 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28826313 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7525661 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27187435 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27187435 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25887113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20609003 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16204359 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12704366 — Biomarker: TAC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAC1; NKA; NKNA; TAC2
Study 21521375 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 19043984 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 26185017 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20854382 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 20854382 — Biomarker: Hepatitis A virus cellular receptor 1
Type: Safety Biomarker (SAF)
Genes: HAVCR1; KIM1; TIM1; TIMD1
Study 16982943 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 15339556 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 10726719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31237183 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 26960912 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 17683996 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18608549 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 18608549 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18608549 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16395099 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8434246 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 8434246 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24903468 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1350237 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 22460854 — Biomarker: PLAT mRNA
Type: Predictive Biomarker (PRD)
Genes: PLAT
Study 11791028 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6763834 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26880694 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12370214 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12370214 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12370214 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25879228 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25879228 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17124431 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17124431 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11578682 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 11578682 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11578682 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28155060 — Biomarker: AADAC mRNA
Type: Predictive Biomarker (PRD)
Genes: AADAC; DAC
Study 24617232 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24617232 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12684359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7772472 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 31849000 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 28526625 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23345050 — Biomarker: WWTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WWTR1; TAZ
Study 8154033 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15459595 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15459595 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11174041 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9253332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3320788 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27714541 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 27714541 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 20684675 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 18201301 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 8702086 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8702086 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 8702086 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 8702086 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 20014909 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17585060 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 14739125 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 14739125 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14739125 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21193552 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30346099 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 25451704 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19673941 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 19673941 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17909199 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17909199 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 23940216 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23940216 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8605789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1874931 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 23791497 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21545190 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16485865 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 424377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19858394 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15918060 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12483234 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 20525323 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 15886860 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 15886860 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 7587256 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30358116 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 17994478 — Biomarker: MHC class I polypeptide-related sequence A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MICA; PERB11.1
Study 23688821 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 19262219 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1544220 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1544220 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 1544220 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study 1544220 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 3907893 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30468238 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24795475 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 22613104 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20830787 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18855259 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29045941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17926619 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17926619 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 17926619 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11512648 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26436865 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26436865 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21852334 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17267590 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17267590 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12528557 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12528557 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9694306 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 31493177 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31493177 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 14530859 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 14530859 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8774208 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29029210 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 29029210 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15010181 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11181149 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11181149 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 3346069 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26308227 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23613825 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 11468228 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25773554 — Biomarker: RIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RIT1; RIBB; RIT; ROC1
Study 15840666 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17492425 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 15726874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9678319 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 1883120 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1883120 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1883120 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31085814 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31085814 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 31085814 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31725608 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31725608 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21530213 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1