AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 29091464 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24269926 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19393996 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 28079773 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28079773 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28079773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23532801 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 19276230 — Biomarker: STAT5A mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT5A; STAT5
Study 19276230 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17299377 — Biomarker: ARG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARG2
Study 17299377 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 17299377 — Biomarker: HAO2 mRNA
Type: Predictive Biomarker (PRD)
Genes: HAO2; HAOX2; GIG16
Study 17299377 — Biomarker: NANOS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS1; NOS1
Study 15116058 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 3555944 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3555944 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29509266 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29509266 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29509266 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 29509266 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 27605607 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 23756569 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 20735258 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2857709 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29022125 — Biomarker: ENPP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ENPP2; ATX; PDNP2
Study 20117403 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 10822316 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10822316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29289332 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 27280850 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27280850 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25062861 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 23224567 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 23224567 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 12928051 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30202916 — Biomarker: CHRNA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA3; NACHRA3
Study 28477944 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28477944 — Biomarker: Urokinase plasminogen activator surface receptor
Type: Monitoring Biomarker (MOI)
Genes: PLAUR; MO3; UPAR
Study 28477944 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1497125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27916737 — Biomarker: SSB mRNA
Type: Predictive Biomarker (PRD)
Genes: SSB
Study 27326239 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 27326239 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 9458425 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17021319 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10807815 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 31830776 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 23963057 — Biomarker: ENPP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ENPP2; ATX; PDNP2
Study 19438817 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 22893323 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 2531992 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 1187279 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30059262 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20625317 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2169368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28024931 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19138366 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 19138366 — Biomarker: ERCC8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC8; CKN1; CSA
Study 15009968 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16226266 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 26576750 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 22421244 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 29189337 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2967028 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 26202487 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 10618281 — Biomarker: SSB mRNA
Type: Predictive Biomarker (PRD)
Genes: SSB
Study 6199153 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 27144937 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 31331782 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 15720929 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23550857 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29427701 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 29427701 — Biomarker: HMGCR mRNA
Type: Predictive Biomarker (PRD)
Genes: HMGCR
Study 29427701 — Biomarker: INSIG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: INSIG1
Study 29427701 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 29427701 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 29427701 — Biomarker: SREBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SREBF1; BHLHD1; SREBP1
Study 29427701 — Biomarker: miR-29a
Type: Monitoring Biomarker (MOI)
Genes: MIR29A
Study 29427701 — Biomarker: miR-29a-3p
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: MIR29A
Study 29427701 — Biomarker: miR-106b
Type: Predictive Biomarker (PRD)
Genes: MIR106B
Study 20210906 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20210906 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20210906 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18156881 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1313761 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25352870 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20332612 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 20332612 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18627368 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 16173137 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 16173137 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 2154513 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12860861 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8890060 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 6366617 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 6366617 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 30144169 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15903281 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15903281 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2540392 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30095747 — Biomarker: IL1RN mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RN; IL1F3; IL1RA
Study 28962661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28962661 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28962661 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12587324 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1785245 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17556705 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8747858 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 811237 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25331270 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 15356963 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28348182 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 15640382 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15640382 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22448211 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22448211 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22448211 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9678530 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28705252 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 26179186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17483124 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study 2176948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25711329 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25711329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18430999 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 11061029 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11061029 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8272250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2961356 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 12046472 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9851273 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26208996 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 11969062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19494532 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 19494532 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 19494532 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17719288 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9660578 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 799567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24026211 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19473611 — Biomarker: CNDP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNDP2; CN2; CPGL; HEL-S-13; PEPA
Study 19473611 — Biomarker: GLS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS2; GA
Study 17950105 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 17950105 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17950105 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 24345886 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27614452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19280340 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19280340 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18629567 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16775668 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15030293 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 365212 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 31857621 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31857621 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27023086 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21170108 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12957262 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 30309994 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 25275513 — Biomarker: SLPI mRNA
Type: Predictive Biomarker (PRD)
Genes: SLPI; WAP4; WFDC4
Study 19460773 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 19460773 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 17515447 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15300574 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 9791046 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 2729751 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 30486858 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28426123 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 28426123 — Biomarker: AXL mRNA
Type: Predictive Biomarker (PRD)
Genes: AXL; UFO
Study 28426123 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28426123 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 14691688 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3729461 — Biomarker: AFM mRNA
Type: Predictive Biomarker (PRD)
Genes: AFM; ALB2; ALBA
Study 3729461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25028994 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25028994 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25028994 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7797925 — Biomarker: Preexisting antibody
Type: Safety Biomarker (SAF)
Study 23617551 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16398842 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31511398 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 28115488 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 24829493 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24829493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23033885 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17123710 — Biomarker: RHOJ mRNA
Type: Predictive Biomarker (PRD)
Genes: RHOJ; ARHJ; RASL7B; RHOI; TCL
Study 9795455 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9795455 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 23972025 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23972025 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 21164503 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study 21164503 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29370352 — Biomarker: TLL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLL1; TLL
Study 24021497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21917907 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 17557312 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12781882 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 31831363 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 31831363 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 31593702 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 31593702 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 28165552 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 28165552 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 28165552 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26030518 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 26030518 — Biomarker: CDK6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK6; CDKN6
Study 26030518 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 17303791 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15519185 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15519185 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23922746 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28409397 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28409397 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23294179 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 11451623 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8052956 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 8052956 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 8052956 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 20190833 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 6223289 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26787637 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26787637 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17616777 — Biomarker: PPARG mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARG; NR1C3
Study 17616777 — Biomarker: ADRB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB3; ADRB3R; B3AR
Study 12471297 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12471297 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12471297 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31999300 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17157112 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 29897564 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29897564 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 26890560 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN