AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 26582873 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24157526 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24157526 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24157526 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 24157526 — Biomarker: Angiopoietin-1
Type: Monitoring Biomarker (MOI)
Genes: ANGPT1; KIAA0003
Study 19339045 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9020593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6540047 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 25582793 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22155918 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22155918 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22155918 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23159393 — Biomarker: PTPRF mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRF; LAR
Study 14623504 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23801606 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23801606 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23801606 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16421364 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10843145 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 10843145 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 30367021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27737602 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15984576 — Biomarker: CPVL mRNA
Type: Predictive Biomarker (PRD)
Genes: CPVL; VLP; PSEC0124; UNQ197/PRO223
Study 8913544 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30203839 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30203839 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18547426 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8524984 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2273527 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30531304 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25935581 — Biomarker: RAPGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 24085466 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 9521833 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 8110557 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 21450118 — Biomarker: Vitamin K-dependent protein C
Type: Safety Biomarker (SAF)
Genes: PROC
Study 3051870 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 15844319 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2160343 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23322362 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 23322362 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17717918 — Biomarker: FGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF2; FGFB
Study 27190323 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 27190323 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 7512336 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 7555472 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23563932 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19166691 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19166691 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29634656 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 29634656 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 16554145 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26852885 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26852885 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26852885 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26852885 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 18376061 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 7442597 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 20635803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17477205 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 30696807 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 26407169 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 30169436 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17299464 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 31264758 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 31264758 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27199314 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 24627416 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 17299108 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 15189919 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 27401338 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27401338 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26826543 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16260426 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16260426 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9564799 — Biomarker: ARID3B mRNA
Type: Predictive Biomarker (PRD)
Genes: ARID3B; BDP; DRIL2
Study 9564799 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27012401 — Biomarker: IGF2R mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF2R; MPRI
Study 27012401 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21450569 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21450569 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2646301 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 17361128 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 17361128 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 17361128 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 17361128 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 17361128 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 17361128 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 15375502 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 10204352 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 27932764 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 7201271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29663701 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 18316629 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16273794 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12610003 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10480767 — Biomarker: NPL mRNA
Type: Predictive Biomarker (PRD)
Genes: NPL; C1orf13
Study 16049806 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 10394161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31647496 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9643529 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9643529 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7621303 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31584311 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31584311 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24198887 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24198887 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27950663 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 1442657 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1442657 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1442657 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 3880685 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26924051 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24271056 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 16266450 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 371021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31392790 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 19826291 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16506871 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 11063279 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11063279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9115065 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1492231 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27244537 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 16236917 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 11869857 — Biomarker: LAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LAT
Study 28112773 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19515791 — Biomarker: Growth/differentiation factor 15
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 19515791 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19515791 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10692976 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6996897 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18832244 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12847427 — Biomarker: PICALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PICALM; CALM
Study 12847427 — Biomarker: CALM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CALM2; CAM2; CAMB
Study 17109866 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 21839850 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16858354 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16858354 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16858354 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15199384 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 3687315 — Biomarker: Urinary total protein
Type: Safety Biomarker (SAF)
Study 3687315 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29363365 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 10215313 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7533226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7533226 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31423576 — Biomarker: EZH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EZH2; KMT6
Study 31423576 — Biomarker: MEF2B mRNA
Type: Predictive Biomarker (PRD)
Genes: MEF2B; XMEF2
Study 31423576 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 31423576 — Biomarker: FOXO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXO1; FKHR; FOXO1A
Study 31423576 — Biomarker: CREBBP mRNA
Type: Predictive Biomarker (PRD)
Genes: CREBBP; CBP
Study 31423576 — Biomarker: CARD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARD11; CARMA1
Study 25706751 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25706751 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19025521 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 8826981 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 1590581 — Biomarker: POR mRNA
Type: Predictive Biomarker (PRD)
Genes: POR; CYPOR
Study 20444749 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16274377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14697441 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11214722 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11704128 — Biomarker: HCG22 mRNA
Type: Predictive Biomarker (PRD)
Genes: HCG22; G2; PBMUCL2
Study 9385564 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 26742305 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 26742305 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26742305 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21212367 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11989571 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11989571 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 26757748 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 26757748 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 10650325 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9094066 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8477064 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 18422771 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 15969877 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 10845571 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 11343005 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9273829 — Biomarker: ALDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH2; ALDM
Study 16759047 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31715306 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 31715306 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31715306 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 31715306 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28699886 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 28699886 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 28699886 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 28699886 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18172922 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 11740262 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30942028 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28426260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19491213 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16967040 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17114190 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 10440120 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9164416 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28412602 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 26781346 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24963611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22543063 — Biomarker: PER3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PER3; GIG13
Study 20139790 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20139790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25824248 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11465092 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11465092 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 11465092 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 11465092 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9486289 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30632290 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28950268 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 28801400 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 23181712 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16687084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3535986 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24760484 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 15877299 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15877299 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12746736 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 11752035 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31596612 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31596612 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9061991 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 7953415 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7953415 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31944487 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31944487 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 16321668 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30473540 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 30473540 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10654875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7751412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30472215 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 29843644 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)