AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 15766363 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 27830924 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27830924 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21114791 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19526394 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19526394 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 15453924 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 23018469 — Biomarker: SLC22A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A2; OCT2
Study 19910173 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 19910173 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 19910173 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 16043728 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6164789 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 28291046 — Biomarker: DDN mRNA
Type: Predictive Biomarker (PRD)
Genes: DDN; KIAA0749
Study 28291046 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 2193475 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6998868 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 26808827 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24774670 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24774670 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 12571527 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1602935 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31272502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10894639 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10894639 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6837336 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21080348 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 21080348 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24727234 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 1720833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6173518 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9606471 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23564348 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 17954367 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19271166 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 19271166 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 16293960 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1659495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26884592 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 25225081 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25225081 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18647201 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 28941056 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 28941056 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6753547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14514628 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7963115 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29723235 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study 21786434 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 15080785 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 15080785 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15080785 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15080785 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 22682536 — Biomarker: CTPS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CTPS1; CTPS
Study 18356694 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18356694 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 18356694 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 18356694 — Biomarker: Apolipoprotein A-IV
Type: Monitoring Biomarker (MOI)
Genes: APOA4
Study 14613023 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24607303 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24607303 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30845291 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15620437 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26746184 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21474498 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 15276394 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11352981 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 26412349 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26412349 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 23679351 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 23679351 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 12786700 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 8973725 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6385051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16234962 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 16234962 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 2127424 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 17550489 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 9688014 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 338851 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 27548910 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 23556995 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 7527108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28111980 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 28111980 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 16681573 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 11781669 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 9264493 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9264493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15253730 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29538579 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27496232 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 27496232 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 27496232 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24241495 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24241495 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 20147896 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 20147896 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 20147896 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 20147896 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 14663041 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 11054627 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11054627 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11054627 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1378155 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29093302 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25233662 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8857017 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 19233760 — Biomarker: DCT mRNA
Type: Predictive Biomarker (PRD)
Genes: DCT; TYRP2
Study 19233760 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 17725246 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15077101 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24612502 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 19009170 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11095060 — Biomarker: TGFBI mRNA
Type: Predictive Biomarker (PRD)
Genes: TGFBI; BIGH3
Study 25775249 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25775249 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23806736 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18085104 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 18085104 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 23188416 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12855334 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 6814471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23343675 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23343675 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 23343675 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 23343675 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 21084270 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 21084270 — Biomarker: CYP27B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 21084270 — Biomarker: CYP24A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP24A1; CYP24
Study 17540200 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17540200 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17540200 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 3802704 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21612468 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11472278 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11472278 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7521724 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7521724 — Biomarker: Tumor-infiltrating lymphocyte
Type: Predictive Biomarker (PRD)
Study 30604674 — Biomarker: RAPGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 28498189 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18581619 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 3045028 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22999398 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9442340 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 9048272 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18779616 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2409356 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19443132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15580176 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8288727 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 8288727 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8288727 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30166301 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study 25602687 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 24200273 — Biomarker: PTBP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTBP2; NPTB; PTB; PTBLP
Study 9123736 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11395041 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 11395041 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 29879606 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 23733326 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 10230328 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8721349 — Biomarker: GLS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS2; GA
Study 28388294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24552382 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24552382 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 16870661 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 16870661 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 11709366 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 28302543 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 28302543 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 28302543 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 15080578 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12243437 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 8109552 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 21569094 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 15175795 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 15175795 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11521726 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11521726 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27717405 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 22232134 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11855559 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 2260546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19548434 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 17679725 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 15910745 — Biomarker: SAA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAA4; CSAA
Study 9874055 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22196835 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17717534 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12441039 — Biomarker: ACAD8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAD8; ARC42; IBD
Study 30328241 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 30328241 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 2645550 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29360701 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29360701 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29360701 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20934573 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 16115151 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 12146000 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 10586564 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 2375291 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 25872126 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19462320 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15257848 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21476961 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19593175 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9112219 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 9112219 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7901248 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 3306128 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 31820537 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 28553078 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28553078 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28553078 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26169960 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20393176 — Biomarker: Lysosomal alpha-glucosidase
Type: Safety Biomarker (SAF)
Genes: GAA
Study 20393176 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20393176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11870127 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 9758298 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29883070 — Biomarker: GATA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GATA3
Study 29883070 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 29883070 — Biomarker: RORC mRNA
Type: Predictive Biomarker (PRD)
Genes: RORC; NR1F3; RORG; RZRG
Study 29883070 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 2906290 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10747531 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25048074 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16193197 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12642354 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10590183 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 9081272 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15860465 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 9510492 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23381968 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 19453846 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 29179781 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29179781 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 29179781 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 29179781 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26069170 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 19368788 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9133547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7883836 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 10576237 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 30900158 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34