AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 11445757 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 11445757 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 3285833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3285833 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 15090799 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9743817 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 20508338 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 20508338 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18829995 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 8579031 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 25995282 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 17524997 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15545824 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 15545824 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15545824 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 11350567 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11350567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2139843 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 2139843 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study 28983938 — Biomarker: NF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF2; SCH
Study 27657522 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 27657522 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27874299 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24780728 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 27481881 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23488690 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23488690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17425758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17425758 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17425758 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15781019 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28685542 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28685542 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 28685542 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28685542 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10782840 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9324342 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 22105574 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 17220631 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 17220631 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11122756 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7930385 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23710960 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21838913 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11433674 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 7599759 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 359215 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31804894 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 24232362 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 16996948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14535968 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30865796 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17379047 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10190880 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11527135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6127907 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31500444 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 31500444 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7795397 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7795397 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23172127 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23172127 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21889769 — Biomarker: APOA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOA5; RAP3; UNQ411/PRO773
Study 21889769 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21889769 — Biomarker: ZPR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZPR1; ZNF259
Study 21889769 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21889769 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18066566 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 12780945 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8882114 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 6501237 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24645800 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 24645800 — Biomarker: NDRG4 mRNA
Type: Predictive Biomarker (PRD)
Genes: NDRG4; BDM1; KIAA1180
Study 24645800 — Biomarker: BMP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BMP3; BMP3A
Study 22503057 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 17587750 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17587750 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29083477 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 26906034 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26906034 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 24694077 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 12516831 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 11938780 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8572785 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 27886382 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27886382 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26186444 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15320983 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9118772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24799608 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22650119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22650119 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20980427 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20980427 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18614167 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12027564 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23650416 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21741642 — Biomarker: HGD mRNA
Type: Predictive Biomarker (PRD)
Genes: HGD; HGO
Study 19359813 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 15858257 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11062381 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 31812946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28230639 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11560566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23032417 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20919540 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18431264 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 17075113 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 11200917 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 11200917 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 1377118 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 1377118 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31005969 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19449344 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11208681 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8500862 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29587666 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 18639628 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18639628 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31795482 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 22293126 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 22293126 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22293126 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22293126 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22293126 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22293126 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22293126 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17234506 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17234506 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16847182 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 11030848 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29763373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18245179 — Biomarker: USH1G mRNA
Type: Predictive Biomarker (PRD)
Genes: USH1G; SANS
Study 1643676 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31171878 — Biomarker: MAP2K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K1; MEK1; PRKMK1
Study 24628035 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 24628035 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19200119 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 3533567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20884014 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20884014 — Biomarker: CCR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 17317388 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 3723158 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24560278 — Biomarker: MT1F mRNA
Type: Predictive Biomarker (PRD)
Genes: MT1F; PRO0376
Study 24560278 — Biomarker: MT2A mRNA
Type: Predictive Biomarker (PRD)
Genes: MT2A; CES1; MT2
Study 22527372 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 10995004 — Biomarker: RARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RARS1; RARS
Study 26963952 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 1290634 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 3937509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30785667 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 16038474 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10708161 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9396090 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2680795 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 25458645 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17542406 — Biomarker: FMN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMN1; FMN; LD
Study 29864505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9790269 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 29239982 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28731609 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25434837 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 22762449 — Biomarker: Vitamin K-dependent protein C
Type: Safety Biomarker (SAF)
Genes: PROC
Study 19627212 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10741628 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10100788 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 23546553 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23546553 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 20031847 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31106666 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28639089 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26940720 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22533447 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7705375 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23538020 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20655105 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14573327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14573327 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30113051 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22115970 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18771430 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18322604 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 15010365 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11588457 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11588457 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1639051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16471172 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12742806 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25350851 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17917517 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10427933 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 31931928 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31931928 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31931928 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 24844352 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 16878429 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8888663 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8888663 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8888663 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8888663 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28645983 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25890643 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 18423151 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18423151 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 18423151 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 18423151 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18423151 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 18423151 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 19051099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14694529 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 14694529 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12586855 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12586855 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15952055 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12575964 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 12037652 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10194172 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 25837980 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 25837980 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 25837980 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 25837980 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 25837980 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21439397 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11920277 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23828452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20335146 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18710018 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15625368 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 3934948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25185831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18027125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7599866 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2347435 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 117999 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 20228421 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 18307459 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15987919 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8853810 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 8853810 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1535185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)