AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 30715779 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23169695 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 19166395 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 15233550 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27282457 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 12907822 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 10976988 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1506543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11922851 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 2148882 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30563932 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 27654012 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 27654012 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 22205554 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10872186 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 9166391 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23865441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10890543 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16508385 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16508385 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16508385 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 16508385 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 9236446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3092699 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27545351 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 24886353 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16896732 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16896732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29715698 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 29715698 — Biomarker: CYP27B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 15881474 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 15881474 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1945604 — Biomarker: KY mRNA
Type: Predictive Biomarker (PRD)
Genes: KY
Study 6812154 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29143550 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 28666704 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25482680 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 19723645 — Biomarker: CDKN1B mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN1B; KIP1; p27
Study 19723645 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 26510505 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 21940058 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21940058 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 18327671 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 18327671 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12800412 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28320765 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 28320765 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 24432622 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 24432622 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 21336952 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19121597 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17722822 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8523049 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 26552348 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 20359549 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18308147 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 10626563 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 8534728 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 27190374 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 20450940 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8975835 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 3070134 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28621003 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7824961 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 7824961 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 27287781 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27287781 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27287781 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 27287781 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23701177 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12749493 — Biomarker: TMPRSS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMPRSS13; MSP; TMPRSS11
Study 9388377 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9388377 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 9388377 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 7945495 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28693601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23333902 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 23333902 — Biomarker: IGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF2; PP1446
Study 23333902 — Biomarker: IGFBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP1; IBP1
Study 23333902 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 18040619 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9692071 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8820898 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6273020 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25970751 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18576295 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6377070 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 31181536 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 29204652 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 21718484 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 10731455 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31526207 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 11166484 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30146282 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 30146282 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30146282 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22421169 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 31535498 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 15265256 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11413106 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 9160758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23782624 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14691193 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 7981992 — Biomarker: ASPRV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASPRV1; SASP
Study 2921096 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31677046 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31256021 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 23952999 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9594206 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9594206 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29523267 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27584019 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 31042621 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 28403269 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26063507 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 26063507 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 26063507 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26063507 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 8875537 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8875537 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 28236984 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 26812001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22855917 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22855917 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15867002 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 12236630 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9808216 — Biomarker: Complement factor D
Type: Safety Biomarker (SAF)
Genes: CFD; DF; PFD
Study 29850922 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19125778 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17493152 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 17493152 — Biomarker: LGALS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LGALS2
Study 16198981 — Biomarker: Osteopontin
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SPP1; BNSP; OPN; PSEC0156
Study 12421198 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 12421198 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 1952135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7150394 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7150394 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28551197 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25327828 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 23419340 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 23419340 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17709710 — Biomarker: GAPDH mRNA
Type: Predictive Biomarker (PRD)
Genes: GAPDH; GAPD; CDABP0047; OK/SW-cl.12
Study 14722031 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 3381314 — Biomarker: CPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPZ
Study 24400937 — Biomarker: AAAS mRNA
Type: Predictive Biomarker (PRD)
Genes: AAAS; ADRACALA; GL003
Study 20837163 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17848393 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17848393 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17848393 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1369703 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27759074 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 27759074 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27759074 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27759074 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 27759074 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23375680 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 11240235 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 28965646 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25608582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18097230 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11819790 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11819790 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7947364 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25637076 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19643495 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 23098348 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28735449 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 28735449 — Biomarker: STAT5A mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT5A; STAT5
Study 18410547 — Biomarker: SLCO1C1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1C1; OATP14; OATP1C1; OATPF; SLC21A14
Study 15634723 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17564561 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 17564561 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7840507 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 7840507 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21844490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14593457 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11403353 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study 11403353 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9590488 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 3139428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27225617 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15112179 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 3884576 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3884576 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22112610 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 22112610 — Biomarker: MRP2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ABCC2; DJS; cMRP
Study 22112610 — Biomarker: ABCG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 17480139 — Biomarker: PAG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAG1; CBP; PAG
Study 2069792 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24249309 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 24249309 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7977145 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18221329 — Biomarker: NANOS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS3; NOS3
Study 18565251 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 7536438 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7536438 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 7536438 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9439530 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9439530 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26024551 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 21097434 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1313467 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25185858 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 9660523 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9660523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26524801 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26524801 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21332248 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 19836621 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16176400 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 16176400 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10412270 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 27528215 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 27528215 — Biomarker: Serum phosphate
Type: Surrogate Endpoint (SUR)
Study 27528215 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21829046 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 7988781 — Biomarker: High-frequency oscillations
Type: Pharmacodynamic Biomarker (PDY)
Study 47702 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19040623 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 16546471 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16546471 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2876575 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9513912 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23888935 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 16352692 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9547164 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31633603 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 29141040 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study 9397397 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 9397397 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 27084093 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22453568 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 22453568 — Biomarker: PDGFRA mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 11701727 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11701727 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 11701727 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28731780 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 26413749 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 19726350 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR