AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24024320 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 24024320 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 9081682 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20606533 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 12142558 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12142558 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 9657628 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7644244 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 7644244 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 2507323 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 2507323 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 26654907 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8815273 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19193781 — Biomarker: KIT
Type: Predictive Biomarker (PRD)
Genes: CD117; SCFR; C-Kit
Study 11598595 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25440329 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25440329 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21921413 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21921413 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21921413 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 21921413 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9101306 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9101306 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23363676 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7921519 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3560070 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 3560070 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 30709725 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24298765 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 12953031 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10651673 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10651673 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12231566 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 12231566 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12231566 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2084236 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25873189 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 20143449 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20143449 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9250827 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25650964 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25650964 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24338119 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 20817859 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 20817859 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17451421 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 17451421 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7920000 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31269419 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 28742643 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 1414966 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26862857 — Biomarker: miR-21
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR21
Study 12873920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10723498 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6890361 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21736853 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16443502 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 8017308 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29131887 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10786962 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 10786962 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10786962 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 4036270 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 25872501 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17192504 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 26463698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23822690 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 11208851 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29472356 — Biomarker: AKT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT3; PKBG
Study 29472356 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 29472356 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 29472356 — Biomarker: CD79B mRNA
Type: Predictive Biomarker (PRD)
Genes: CD79B; B29; IGB
Study 29472356 — Biomarker: PIK3CD mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CD
Study 29472356 — Biomarker: SYK mRNA
Type: Predictive Biomarker (PRD)
Genes: SYK
Study 29472356 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 28327934 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 23701382 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16485576 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10647074 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 10647074 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2202547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6783979 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 25408262 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 25408262 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 25408262 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 23886915 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16691030 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11778974 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 7934970 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29084372 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 20724597 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 8800496 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6400113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15764762 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15764762 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 15764762 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 10100058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17124558 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12510010 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 12510010 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12510010 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 30383646 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10065691 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 31483000 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 19042026 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 19057518 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 19057518 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19057518 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7655766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31862764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29773696 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 28148500 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25445634 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17898366 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15281537 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16169869 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 16169869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14690787 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 8959286 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 26184491 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 26184491 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23738530 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 11055468 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11055468 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9495994 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9495994 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2873740 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19143675 — Biomarker: SLPI mRNA
Type: Predictive Biomarker (PRD)
Genes: SLPI; WAP4; WFDC4
Study 16397514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24021709 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24021709 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24021709 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24021709 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9427904 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30587148 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12351469 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31443789 — Biomarker: RPE65 mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE65
Study 14513291 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 27417288 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27417288 — Biomarker: Urokinase plasminogen activator surface receptor
Type: Monitoring Biomarker (MOI)
Genes: PLAUR; MO3; UPAR
Study 22196131 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 17407159 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 12511851 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 535845 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30670737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30670737 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30670737 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25001663 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25001663 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25001663 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 25001663 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25001663 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18805589 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12411657 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 12411657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20175802 — Biomarker: SLC35A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC35A2; UGALT; UGT; UGTL
Study 15374773 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15374773 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15374773 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15117561 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15117561 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15117561 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28027521 — Biomarker: IRF7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRF7
Study 19073361 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19073361 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15078732 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 1234497 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16425428 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11756059 — Biomarker: Glycerol backbone
Type: Safety Biomarker (SAF)
Study 9526817 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26238111 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24145706 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 16939542 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8628460 — Biomarker: CNTF mRNA
Type: Predictive Biomarker (PRD)
Genes: CNTF
Study 29908670 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 29908670 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29908670 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 19148430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10486678 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10486678 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7762497 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2086672 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 2086672 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 30982177 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 23844756 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26578370 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1634641 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1634641 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22643160 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 15110397 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15110397 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15110397 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2643863 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2643863 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2643863 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29203734 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 29203734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18031595 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18031595 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10447899 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31680138 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 30339627 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 30339627 — Biomarker: BTC mRNA
Type: Predictive Biomarker (PRD)
Genes: BTC
Study 18287375 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3971390 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22248352 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9121997 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 1655262 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17342417 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17342417 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17342417 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 9479684 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9479684 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 9479684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31523014 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18728933 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8292466 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30660609 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 30660609 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 21663652 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14618196 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23265076 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7978185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26031566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8927880 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20396715 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31164288 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 21732833 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19467054 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 8336198 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31614946 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 31614946 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31614946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19649245 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 10100071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8738670 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12742010 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 3903788 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11413075 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 18056743 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8704119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15717259 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27440084 — Biomarker: Calgranulin B
Type: Predictive Biomarker (PRD)
Genes: S100A9; CAGB; CFAG; MRP14
Study 24446062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20561282 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1