AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 25915834 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 18385391 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18385391 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 16437738 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12915954 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 29731121 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27833172 — Biomarker: MSMB mRNA
Type: Predictive Biomarker (PRD)
Genes: MSMB; PRSP
Study 29453374 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18663165 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31008751 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 24616335 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2409371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12916011 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29570512 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8116059 — Biomarker: LTB mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB; TNFC; TNFSF3
Study 8964641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14630885 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 14630885 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8671857 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8671857 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1315826 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20299607 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20299607 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 12675179 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 30844848 — Biomarker: MXD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MXD1; MAD
Study 25099071 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25099071 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 25099071 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23362296 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23362296 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20844049 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 20844049 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20844049 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 15671215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15671215 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10933617 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9016421 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 9016421 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29878617 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 14583178 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 9987171 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 3521691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27605230 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27605230 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 27605230 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8034872 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 29798120 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 9408065 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27740618 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25007667 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7856526 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1950173 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30929965 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 25963404 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 25963404 — Biomarker: Nqo1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: NQO1; DIA4; NMOR1
Study 8324915 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 3540308 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30208589 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 23845320 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18829508 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 16485512 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1743319 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 30740935 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24342820 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 24342820 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24342820 — Biomarker: SLC25A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A3; PHC; OK/SW-cl.48
Study 17580725 — Biomarker: GAL3ST1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAL3ST1; CST
Study 31593528 — Biomarker: DPT mRNA
Type: Predictive Biomarker (PRD)
Genes: DPT
Study 8887059 — Biomarker: EIF2AK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EIF2AK2; PKR; PRKR
Study 1712273 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 6761849 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 30738426 — Biomarker: Lysosomal acid glucosylceramidase
Type: Pharmacodynamic Biomarker (PDY)
Genes: GBA1; GBA; GC; GLUC
Study 25974251 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21076273 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19772786 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 15593057 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 15593057 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15593057 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8072255 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 3134810 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23826093 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 21950148 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9802627 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29993218 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 29206824 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26136585 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 18303125 — Biomarker: TNFSF13 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 25841237 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 18073318 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18929400 — Biomarker: RRH mRNA
Type: Predictive Biomarker (PRD)
Genes: RRH
Study 16444853 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 31778115 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 27371291 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9625132 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 30954341 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28502543 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 10188768 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10188768 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 10188768 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7493146 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22387567 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 19145426 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 8052457 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1696670 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18807218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15548718 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7946944 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 15165407 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15165407 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25892145 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24165884 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 11768727 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16600745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9315415 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 22297398 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15976341 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15976341 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28329080 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 28329080 — Biomarker: Macrophage inflammatory protein 1-alpha
Type: Monitoring Biomarker (MOI)
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 23646475 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 23646475 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23646475 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23646475 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 3414546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28523945 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25757964 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 24311403 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24311403 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24311403 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16861093 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9756109 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 27967328 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 27967328 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 23978392 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 9350661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7537921 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 29972310 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29972310 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22832068 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 6981173 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17322149 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9688487 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 2783352 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25577145 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 25577145 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 17467513 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2892582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24394704 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24394704 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24394704 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 22426371 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18536785 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16640103 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31123801 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20833738 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 20833738 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20833738 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16338269 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11889016 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 22042958 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 15161788 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 11549098 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25240692 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8274414 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 8274414 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 3011048 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16877482 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16877482 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30108162 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30108162 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19512875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17445178 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 14514942 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 14514942 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 26577998 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25247319 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 8701508 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23866471 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 23866471 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 23866471 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16138974 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16138974 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12012289 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 8903665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8903665 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 18728056 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 18728056 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 19786145 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19786145 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21393114 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21393114 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14642699 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 14642699 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31111250 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 28985434 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 26573509 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 29342248 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 27677387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22282478 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 20104189 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14961168 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12458652 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9657564 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9657564 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 9657564 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9657564 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 9657564 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21679485 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 12488121 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 12488121 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 30119694 — Biomarker: LTB4R mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 25183511 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 2038782 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 26667921 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10759236 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 29406176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15992652 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12637120 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 1319111 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3897044 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20403471 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12354174 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12354174 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 12354174 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 12354174 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 10965249 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 28399620 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 23921615 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 23921615 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9382123 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 8282350 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8282350 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30274540 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26087670 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 21098626 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 23046599 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23046599 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 23046599 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 20730514 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19430807 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 12482564 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 27994711 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27994711 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 27994711 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27994711 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF