AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 29906251 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 23143762 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 14750100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11591234 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 9702314 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7520210 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 24183196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22099625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12643410 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 2008948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6800869 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6800869 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22658512 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 16448282 — Biomarker: PLXNB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLXNB1; KIAA0407; PLXN5; SEP
Study 28793772 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 28793772 — Biomarker: HERPUD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HERPUD1; HERP; KIAA0025; MIF1
Study 19697823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11302274 — Biomarker: AFM mRNA
Type: Predictive Biomarker (PRD)
Genes: AFM; ALB2; ALBA
Study 8103527 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29735284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18033318 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 28542080 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25118999 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25118999 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 17339482 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 17339482 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16491109 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 16491109 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 16491109 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15488350 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26119653 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16377918 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16377918 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30701858 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 30642922 — Biomarker: DHFR
Type: Safety Biomarker (SAF)
Genes: DHFR1
Study 11908491 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10102784 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 19433689 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 16116336 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22742720 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 22742720 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 19548438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9655713 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 7640430 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 26269239 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 26269239 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17349073 — Biomarker: APOB mRNA
Type: Predictive Biomarker (PRD)
Genes: APOB
Study 9590490 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 29386007 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 16641607 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14640385 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1476763 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31449880 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29330461 — Biomarker: GPR119 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPR119
Study 29330461 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 7848788 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3057139 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7759449 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30973544 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30973544 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30973544 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15076172 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16778330 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16778330 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11053725 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 28407637 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28407637 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 1587408 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 3884409 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3884409 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 25074984 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 23095425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12469706 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12469706 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 1770568 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25825944 — Biomarker: IHH mRNA
Type: Predictive Biomarker (PRD)
Genes: IHH
Study 19265599 — Biomarker: TRIM63 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 26316013 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18463831 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 20505674 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20505674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8739928 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 8739928 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 27418594 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11788184 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22285857 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27179738 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22893166 — Biomarker: COPE mRNA
Type: Predictive Biomarker (PRD)
Genes: COPE
Study 27661412 — Biomarker: miR-16
Type: Safety Biomarker (SAF)
Study 27661412 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27661412 — Biomarker: miR-106a
Type: Predictive Biomarker (PRD)
Genes: MIR106A
Study 27661412 — Biomarker: miR-223
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR223
Study 27661412 — Biomarker: miR-652
Type: Safety Biomarker (SAF)
Genes: MIR652
Study 27661412 — Biomarker: miR-18a
Type: Safety Biomarker (SAF)
Genes: MIR18A
Study 14639584 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study 31257591 — Biomarker: CST9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CST9; CLM; CTES7A
Study 12042231 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 7762855 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1702899 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 1702899 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1702899 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 1702899 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 1702899 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 1702899 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 1702899 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1702899 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 25596266 — Biomarker: MLH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MLH1; COCA2
Study 25596266 — Biomarker: FCGR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR2A; CD32; FCG2; FCGR2A1; IGFR2
Study 25596266 — Biomarker: FCGR3A mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 30388194 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 12532901 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12532901 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 12532901 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 28349667 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 28349667 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 28349667 — Biomarker: Heart fatty acid-binding protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FABP3; FABP11; MDGI
Study 28349667 — Biomarker: CPT1B mRNA
Type: Predictive Biomarker (PRD)
Genes: CPT1B; KIAA1670
Study 24050377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17910386 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17910386 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16254264 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 12440605 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 10208143 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2515940 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 27756786 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 27756786 — Biomarker: AMACR mRNA
Type: Predictive Biomarker (PRD)
Genes: AMACR
Study 29392002 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 14691415 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22332908 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 22332908 — Biomarker: CCND2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND2
Study 27803139 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10826565 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8858747 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1515637 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27463412 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27463412 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19609570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1906441 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 30902753 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30902753 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30902753 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23260261 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23260261 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17644340 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11233386 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19262561 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16412224 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16412224 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 25584002 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21523806 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study 16935774 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 16935774 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 16935774 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29677687 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 22305632 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12830442 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30103738 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 30103738 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 24910976 — Biomarker: FLCN mRNA
Type: Predictive Biomarker (PRD)
Genes: FLCN; BHD
Study 19133217 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19133217 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 16364669 — Biomarker: TAC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAC1; NKA; NKNA; TAC2
Study 14605526 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 14605526 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 14605526 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 14605526 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 21592475 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 15090314 — Biomarker: FGR mRNA
Type: Predictive Biomarker (PRD)
Genes: FGR; SRC2
Study 26250745 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 23878833 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 23878833 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 20568431 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1822255 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20235224 — Biomarker: SHD mRNA
Type: Predictive Biomarker (PRD)
Genes: SHD
Study 12166344 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8292907 — Biomarker: CPE mRNA
Type: Predictive Biomarker (PRD)
Genes: CPE
Study 12536743 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 23303870 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15983311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6335905 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 31462554 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 25680689 — Biomarker: Lysosomal alpha-glucosidase
Type: Safety Biomarker (SAF)
Genes: GAA
Study 30208601 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30208601 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30208601 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10449104 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8960851 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8960851 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24576401 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 24576401 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 24576401 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17986164 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 9707026 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6119685 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6119685 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31713733 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28859947 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 8021578 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2686488 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25464260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27323347 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 25939514 — Biomarker: ARVCF mRNA
Type: Predictive Biomarker (PRD)
Genes: ARVCF
Study 21095135 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18240145 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 14610014 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 14610014 — Biomarker: KIT
Type: Predictive Biomarker (PRD)
Genes: CD117; SCFR; C-Kit
Study 14610014 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 14610014 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 8817142 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 26787023 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 26787023 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 19733931 — Biomarker: CHRNA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA3; NACHRA3
Study 19733931 — Biomarker: CHRNA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA5; NACHRA5
Study 19733931 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 1467386 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 17517342 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9036306 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26290435 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 26290435 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 23104705 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11034431 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31877910 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 31877910 — Biomarker: Platelet-derived growth factor B
Type: Pharmacodynamic Biomarker (PDY)
Genes: PDGFB; PDGF2; SIS
Study 21877927 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8792921 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 22762147 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16279568 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 16279568 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 7930300 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21925942 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24728665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21545606 — Biomarker: SLC10A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC10A2; ASBT; ISBT; NTCP2
Study 21545606 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 19644896 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19644896 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17380548 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25760679 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21362268 — Biomarker: MCM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCM2; BM28; CCNL1; CDCL1; KIAA0030