AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 8575118 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8575118 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2213283 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2213283 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19487926 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 16730270 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11520524 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11520524 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8326293 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8326293 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 21397541 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 9350068 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 25912040 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 8084972 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21857142 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21857142 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21857142 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19216014 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17926823 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8128835 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 3651264 — Biomarker: EDAR mRNA
Type: Predictive Biomarker (PRD)
Genes: EDAR; DL
Study 26021563 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 28919811 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 23392882 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 21843919 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17244641 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 30194765 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25495109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25495109 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18281656 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 12676601 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 10760528 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 1424429 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 29921339 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 22797101 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11669594 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16620353 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 14960129 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 27028380 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 20610442 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25651367 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21804283 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21804283 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21804283 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11226005 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 23078574 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 11916764 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 11916764 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11916764 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1981075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25431280 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24658707 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 542823 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31834252 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31834252 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17395677 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23422495 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17182126 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9643615 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 31546738 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28454836 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31446217 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15221507 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28121670 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26192006 — Biomarker: SLC38A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 21343579 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16392026 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15164191 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 11152791 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 23292928 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 20825712 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 18094315 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 29615088 — Biomarker: RHOJ mRNA
Type: Predictive Biomarker (PRD)
Genes: RHOJ; ARHJ; RASL7B; RHOI; TCL
Study 27179112 — Biomarker: FCGR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR2A; CD32; FCG2; FCGR2A1; IGFR2
Study 27179112 — Biomarker: FCGR3A mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 27179112 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27179112 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 24899618 — Biomarker: MVB12B mRNA
Type: Predictive Biomarker (PRD)
Genes: MVB12B; C9orf28; FAM125B
Study 21384066 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9162432 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16860976 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16009907 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2189040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23461895 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 18036359 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18036359 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18036359 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2076408 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9554680 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9554680 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11300610 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31302249 — Biomarker: HSPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPB1; HSP27; HSP28
Study 31302249 — Biomarker: HSPA1A mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA1A; HSP72; HSPA1; HSX70
Study 31302249 — Biomarker: HSPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPD1; HSP60
Study 31302249 — Biomarker: HSPA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA5; GRP78
Study 30625106 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 18326331 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10068849 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 24528783 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15083312 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15083312 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 12133516 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19937427 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18415823 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9470081 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9470081 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3673207 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 17565921 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 17658632 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17658632 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11842026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28567578 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28567578 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11673582 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 9502190 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 30124725 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 30124725 — Biomarker: WWTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WWTR1; TAZ
Study 26205759 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 26205759 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24604685 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 1792820 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24906450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20197767 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 1889248 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 21994966 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1711274 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29510423 — Biomarker: Interleukin 6 receptor alpha
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: IL6R
Study 18979450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9358957 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29866368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29866368 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21319355 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17046300 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 2654792 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 2654792 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 18374753 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30592022 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 28256066 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25063045 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25063045 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17173906 — Biomarker: SPAG9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPAG9; HSS; KIAA0516; MAPK8IP4; SYD1; HLC6
Study 15885986 — Biomarker: WWTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WWTR1; TAZ
Study 8573425 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 28087723 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18534230 — Biomarker: ABCC6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC6; ARA; MRP6
Study 10071916 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7480526 — Biomarker: SLC10A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC10A3; DXS253E; P3
Study 7480526 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 23603824 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23603824 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23603824 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11572892 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11572892 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 8156337 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8156337 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15814212 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8729094 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29967037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16228107 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 16228107 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24671897 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20182456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15704683 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 11809596 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 11809596 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 11809596 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 1791611 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9327093 — Biomarker: POMC mRNA
Type: Predictive Biomarker (PRD)
Genes: POMC
Study 9327093 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20096897 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20096897 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18029465 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12095664 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12095664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2786009 — Biomarker: FBL mRNA
Type: Predictive Biomarker (PRD)
Genes: FBL; FIB1; FLRN
Study 31384899 — Biomarker: SLA mRNA
Type: Predictive Biomarker (PRD)
Genes: SLA; SLAP; SLAP1
Study 28235974 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26416653 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 26569501 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 11323731 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7943831 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 7943831 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 24512953 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 23464930 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16860045 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14624371 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 14624371 — Biomarker: CCR2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCR2; CMKBR2
Study 14624371 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 30292481 — Biomarker: STUB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STUB1; CHIP; PP1131
Study 3034021 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3034021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3034021 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 20099948 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 24393424 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 24393424 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 8966062 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28143564 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26060823 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 20671652 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8551786 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 8551786 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8551786 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8551786 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8551786 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 31615771 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31615771 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20581719 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 9350366 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31779697 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31779697 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 31779697 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 21362524 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21362524 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 14622826 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27276758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19842973 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16723320 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 25549639 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 22348270 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15925739 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15925739 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15925739 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31735560 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 30399455 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 22617578 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20223838 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 11144061 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 1667693 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 6332953 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 22499404 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 22499404 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 11715499 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 2218653 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 23551402 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 23551402 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16123763 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 23660437 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 23660437 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 16978648 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL