AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31819995 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24046462 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22490626 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2665492 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2665492 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19715461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11450767 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 11450767 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 18165968 — Biomarker: CHRNA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA5; NACHRA5
Study 10760103 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10760103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1445966 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26062731 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26062731 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 26062731 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 26062731 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21885980 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19489848 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 16769348 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7527112 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 14530867 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 28154462 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 24158787 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24158787 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 20379145 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 15482516 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29789220 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29789220 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 26710696 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 23433188 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 23433188 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16568202 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 10539814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1752890 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 6282105 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 31397288 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 30221912 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25248418 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 10930147 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12771003 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 1506124 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30179727 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19808266 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19808266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12174922 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8882570 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 12069102 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28757482 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 21762358 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21762358 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19347979 — Biomarker: GCLC mRNA
Type: Predictive Biomarker (PRD)
Genes: GCLC; GLCL; GLCLC
Study 19347979 — Biomarker: GPX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPX1
Study 8968180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25811286 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16214026 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16214026 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16214026 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 2572609 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25940675 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 25940675 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 25940675 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25940675 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23836190 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23836190 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19692495 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 12066721 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 7867683 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2092 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9866361 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 7649579 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30701387 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 30701387 — Biomarker: SQSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SQSTM1; ORCA; OSIL
Study 30701387 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 25368978 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 25368978 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 24673467 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 8598936 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 28150855 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 28150855 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 2858215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14648210 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 29484149 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study 29484149 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 29484149 — Biomarker: AZIN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AZIN2; ADC; KIAA1945; ODCP
Study 22998978 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 22998978 — Biomarker: NPC1L1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NPC1L1
Study 18624109 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 10954008 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 9411420 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31810744 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25595117 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 14738417 — Biomarker: SULT1A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SULT1A3; STM
Study 29338111 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26584856 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28470676 — Biomarker: ACACB mRNA
Type: Predictive Biomarker (PRD)
Genes: ACACB; ACC2; ACCB
Study 17893531 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study 2048574 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16389668 — Biomarker: UBR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: UBR5; EDD; EDD1; HYD; KIAA0896
Study 1889973 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 12757116 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 6382127 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 8707476 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 31494945 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29599611 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 26913649 — Biomarker: Vascular endothelial cadherin
Type: Safety Biomarker (SAF)
Genes: CDH5
Study 15559483 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11516109 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 11516109 — Biomarker: TOX mRNA
Type: Predictive Biomarker (PRD)
Genes: TOX; KIAA0808
Study 11516109 — Biomarker: REL mRNA
Type: Predictive Biomarker (PRD)
Genes: REL
Study 8388949 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 6370703 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 6370703 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29849487 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24272364 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 19282749 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23945386 — Biomarker: WT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WT1
Study 23945386 — Biomarker: Epithelial cadherin
Type: Predictive Biomarker (PRD)
Genes: CDH1; CDHE; UVO
Study 12932090 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 394870 — Biomarker: MERTK mRNA
Type: Predictive Biomarker (PRD)
Genes: MERTK; MER
Study 15126758 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 9470910 — Biomarker: GLS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS2; GA
Study 31728714 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 21808761 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 2772103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25196702 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 25196702 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 25196702 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 23623755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3090723 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29703633 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 29703633 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 29703633 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 29703633 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29703633 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24000053 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8141443 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8141443 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29100829 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21822144 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 16219327 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 10670394 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9147709 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29937273 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 25332468 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 16749353 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 10489396 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27658839 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19285200 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1534256 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3884224 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 30394347 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9692706 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25496338 — Biomarker: GRIK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIK1; GLUR5
Study 17187496 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15713726 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1871801 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 6355851 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28841667 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 28841667 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25903259 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 25903259 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19776136 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 19776136 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 19776136 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 10685992 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 8279224 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30626597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31519288 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23243167 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 8404101 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 8404101 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8404101 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 26285704 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12783234 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 26432671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16924007 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 10406828 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30293332 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30293332 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3987781 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30601920 — Biomarker: GMCL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GMCL2; GCL; GMCL1L; GMCL1P1
Study 15631889 — Biomarker: ZDHHC8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZDHHC8; KIAA1292; ZDHHCL1; ZNF378
Study 10490854 — Biomarker: FXYD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FXYD1; PLM
Study 20605840 — Biomarker: Connecting peptide
Type: Safety Biomarker (SAF)
Genes: AHSG; FETUA; PRO2743
Study 11233547 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 26846078 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26846078 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26846078 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 12883972 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3541623 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3541623 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 3541623 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23953553 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31724337 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 31724337 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30396363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23114104 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19874329 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17585215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10930636 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 4025773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27769202 — Biomarker: LTB4R mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 11063182 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28404197 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 25022690 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 10232413 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 8912740 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 15337326 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 9686768 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 29722110 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 29722110 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 14644865 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9209244 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 8260476 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 2893564 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22374331 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22374331 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 22374331 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 22374331 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 12464992 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10657735 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 2173282 — Biomarker: ADCY10 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADCY10; SAC
Study 28086896 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19265046 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12728284 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28847198 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28847198 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 28847198 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28847198 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28847198 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28847198 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 12615625 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29915617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26894924 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24935613 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8578093 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23045591 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 23045591 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 23045591 — Biomarker: NDRG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NDRG1; CAP43; DRG1; RTP
Study 23045591 — Biomarker: SLC7A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC7A5; CD98LC; LAT1; MPE16
Study 23045591 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1