AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 14997962 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10849526 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10849526 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 10849526 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10849526 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8210613 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26082887 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 20881606 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15940143 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15940143 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 15940143 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25123988 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 22044402 — Biomarker: Fatty acid amide hydrolase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: FAAH; FAAH1
Study 21039313 — Biomarker: 14-3-3 protein sigma
Type: Predictive Biomarker (PRD)
Genes: SFN; HME1
Study 21039313 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23896353 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 19526040 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19526040 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19526040 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 11590675 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 27506742 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27506742 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 14643271 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 27466699 — Biomarker: SOCS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOCS1; SSI1; TIP3
Study 27466699 — Biomarker: CISH mRNA
Type: Predictive Biomarker (PRD)
Genes: CISH; G18
Study 27466699 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27466699 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 22161686 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20061334 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 7803596 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 8586009 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 8586009 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1967533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27128565 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19541578 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19541578 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8117174 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15675430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9658726 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 28041830 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 24283136 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21150784 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11548842 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 8279691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3495151 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30514319 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30514319 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 20798196 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 15721728 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11910657 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24965700 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26122230 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20652275 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20652275 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20652275 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20652275 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20652275 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18988907 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9075853 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9075853 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9505980 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2860041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30589035 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27389564 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 19713952 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 19713952 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 9846013 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 9846013 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 9846013 — Biomarker: CD7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD7
Study 9846013 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1071702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29141164 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 23992877 — Biomarker: KCNK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNK3; TASK; TASK1
Study 23992877 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 17021714 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17021714 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15104559 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2899719 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31784746 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31784746 — Biomarker: CADPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CADPS; CAPS; CAPS1; KIAA1121
Study 12297167 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7847429 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2111981 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28655715 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 28655715 — Biomarker: CBR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CBR1; CBR; CRN; SDR21C1
Study 14693576 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 11836046 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11836046 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 17047639 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2157450 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 393519 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23147173 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 16108933 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31985471 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 29720440 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1541981 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 26137537 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26137537 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 26137537 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 26137537 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 23198737 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9781939 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7942731 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 7942731 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 25469044 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 25469044 — Biomarker: BOC mRNA
Type: Predictive Biomarker (PRD)
Genes: BOC; UNQ604/PRO1190
Study 23122795 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23122795 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 18599165 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 15850494 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 11802206 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 11802206 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 11802206 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 26258842 — Biomarker: CARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARS1; CARS
Study 26258842 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 20842417 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11457465 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 7870008 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 25275341 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 20667838 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26312582 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11104393 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 11104393 — Biomarker: Vitamin K-dependent protein C
Type: Safety Biomarker (SAF)
Genes: PROC
Study 8445231 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 8445231 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8445231 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 27139431 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24481415 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 17343310 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31814312 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26978418 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 12208595 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12208595 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19242322 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9696260 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 2759945 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16243460 — Biomarker: REL mRNA
Type: Predictive Biomarker (PRD)
Genes: REL
Study 8898770 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6371575 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 30821053 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30821053 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17241150 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15741434 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 27215836 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22718840 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 22718840 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 18277064 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18277064 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15711829 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19384186 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 12812865 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 8815751 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31741126 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 28454014 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 25754396 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23150126 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23150126 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9786807 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31182183 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 31182183 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 23945072 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study 15976213 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15976213 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12598346 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 2137888 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 29784890 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 7573783 — Biomarker: ALDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH2; ALDM
Study 25456867 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 25456867 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8880078 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 1824707 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 6851041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23288870 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22024001 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 22024001 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 16922703 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16922703 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16922703 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16922703 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 16922703 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 3174151 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11790211 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 10430735 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31140297 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24991733 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 24991733 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 17391164 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7749424 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31076261 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 31076261 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31076261 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20055751 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10082498 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2405555 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29781483 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26707220 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26707220 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18783876 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 11668312 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31010703 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 22285946 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 12736474 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8653836 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 8653836 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8653836 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 3327445 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31948661 — Biomarker: PTPRF mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRF; LAR
Study 1826912 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 6628498 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23299853 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 21174007 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7905101 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31490025 — Biomarker: ELANE mRNA
Type: Predictive Biomarker (PRD)
Genes: ELANE; ELA2
Study 31490025 — Biomarker: PRTN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRTN3; MBN
Study 12560299 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10716371 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8231034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3544940 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26829083 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 20354032 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25693055 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 15513324 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 3142242 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 3142242 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 19758358 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1860763 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29985202 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26905703 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16533865 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 16533865 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1410729 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 20404622 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 10513830 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6181329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31670790 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 30623408 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 27464957 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22535635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15072869 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 22867630 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 22867630 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12057066 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2