AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT01950793 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT05384418 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study NCT01032291 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT00396006 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT03739736 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT04547907 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01940250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02135029 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03941457 — Biomarker: ROBO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROBO1; DUTT1
Study NCT00531557 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT02382029 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study NCT03292055 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT03292055 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02080897 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study NCT01028534 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04676841 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study NCT02154100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02154100 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study NCT02154100 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02480491 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study NCT01316757 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00448851 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study NCT00704483 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00350272 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00908869 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00364572 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01118520 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT01865812 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03073018 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT01636505 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study NCT02319161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04025502 — Biomarker: Auditory steady-state response
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04290793 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04376684 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT03440736 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03440736 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00372372 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02519894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03932422 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00491387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00491387 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT01225575 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study NCT00159250 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study NCT00654407 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02344680 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT00390325 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT02419742 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04712890 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT04712890 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study NCT04712890 — Biomarker: BARD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BARD1
Study NCT04712890 — Biomarker: CHEK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHEK1; CHK1
Study NCT04712890 — Biomarker: CHEK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHEK2; CDS1; CHK2; RAD53
Study NCT04712890 — Biomarker: FANCL mRNA
Type: Predictive Biomarker (PRD)
Genes: FANCL; PHF9
Study NCT04712890 — Biomarker: PALB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PALB2; FANCN
Study NCT04712890 — Biomarker: PPP2R2A mRNA
Type: Predictive Biomarker (PRD)
Genes: PPP2R2A
Study NCT04712890 — Biomarker: RAD51B mRNA
Type: Predictive Biomarker (PRD)
Genes: RAD51B; RAD51L1; REC2
Study NCT04712890 — Biomarker: RAD51C mRNA
Type: Predictive Biomarker (PRD)
Genes: RAD51C; RAD51L2
Study NCT00843583 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02581956 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT01610440 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study NCT01610440 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT01054781 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT03830060 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00070187 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT00070187 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT00520975 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00520975 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT01524848 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study NCT01524848 — Biomarker: PDGFRA mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study NCT01524848 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01555268 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01653496 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study NCT01016444 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study NCT01180673 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04660825 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03031808 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02598427 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01774786 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03978260 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT04996459 — Biomarker: POLE mRNA
Type: Predictive Biomarker (PRD)
Genes: POLE; POLE1
Study NCT04996459 — Biomarker: POLD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: POLD1; POLD
Study NCT02157155 — Biomarker: PNPLA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PNPLA2; ATGL; FP17548
Study NCT03099876 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT01492322 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study NCT02694406 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT02872896 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02419404 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04839094 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT04246606 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00977132 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01522768 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01964274 — Biomarker: Cholinesterase
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: BCHE; CHE1
Study NCT02363725 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00819338 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT00657241 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT01802658 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02916615 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00118976 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT01393405 — Biomarker: Plasma DNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT00708942 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study NCT00708942 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study NCT02659527 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study NCT02659527 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03303404 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03900000 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01237873 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00616265 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03632187 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03632187 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study NCT03632187 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study NCT00745992 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT01535196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03862274 — Biomarker: Tripeptidyl-peptidase I
Type: Predictive Biomarker (PRD)
Genes: TPP1; CLN2; GIG1; UNQ267/PRO304
Study NCT02034786 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT06301893 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06301893 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study NCT00661076 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT02799758 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02285101 — Biomarker: Arginase-1
Type: Safety Biomarker (SAF)
Genes: ARG1
Study NCT03689998 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03689998 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study NCT04283006 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT04283006 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study NCT02778412 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study NCT04702204 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03592147 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00113152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01224847 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT04586946 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT03154554 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study NCT05024500 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT03163888 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01374685 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT04130243 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT00727753 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT02748213 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03758196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00002504 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT02130661 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT00641407 — Biomarker: NPL mRNA
Type: Predictive Biomarker (PRD)
Genes: NPL; C1orf13
Study NCT03359642 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00659256 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00361179 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT00323492 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00323492 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03828812 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02374645 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02374645 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03143699 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01648855 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01648855 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT03830944 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT04863755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03630809 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01386736 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05525156 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT02191228 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT05200754 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT01712256 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00169143 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT00590109 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT00590109 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study NCT01772303 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study NCT01132482 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study NCT00696514 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT02684643 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01441674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02631863 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study NCT04294511 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02771483 — Biomarker: GCA mRNA
Type: Predictive Biomarker (PRD)
Genes: GCA; GCL
Study NCT04254978 — Biomarker: KDM1A mRNA
Type: Predictive Biomarker (PRD)
Genes: KDM1A; AOF2; KDM1; KIAA0601; LSD1
Study NCT02270164 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01237158 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study NCT01147861 — Biomarker: HCAR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: HCAR2; GPR109A; HCA2; HM74A; NIACR1
Study NCT03406858 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02881242 — Biomarker: MAP2K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K1; MEK1; PRKMK1
Study NCT03832621 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study NCT03832621 — Biomarker: MLH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MLH1; COCA2
Study NCT03832621 — Biomarker: DNA mismatch repair protein MSH2
Type: Predictive Biomarker (PRD)
Genes: MSH2
Study NCT03832621 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT03832621 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study NCT03936361 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study NCT01759108 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02808130 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study NCT03016884 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02952339 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT03263208 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT04567875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02296385 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study NCT02514837 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study NCT04174287 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04143139 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT04839159 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT04839159 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04839159 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT04839159 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT00409617 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02797847 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study NCT02532296 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study NCT00271089 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT01708174 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study NCT00921180 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT02437955 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00729183 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00663104 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02628795 — Biomarker: TNF-related weak inducer of apoptosis
Type: Predictive Biomarker (PRD)
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study NCT01064492 — Biomarker: DGAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DGAT1; AGRP1; DGAT
Study NCT00600938 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study NCT02741908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01048021 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT00959842 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03645655 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study NCT03645655 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study NCT02893072 — Biomarker: MNT mRNA
Type: Predictive Biomarker (PRD)
Genes: MNT; BHLHD3; ROX
Study NCT00533533 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study NCT00702403 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT00702403 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT02381808 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02381808 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02381808 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT02381808 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study NCT01329640 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02695745 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01157507 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study NCT04375488 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT02564614 — Biomarker: Hypoxia-inducible factor 1-alpha
Type: Predictive Biomarker (PRD)
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study NCT04369794 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT03921931 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT00433056 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT02476968 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT02476968 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study NCT02463656 — Biomarker: PORCN mRNA
Type: Predictive Biomarker (PRD)
Genes: PORCN; MG61; PORC; PPN