AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 28199814 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19349290 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20075530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2144018 — Biomarker: XRCC1
Type: Safety Biomarker (SAF)
Genes: RCC
Study 27616331 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26453532 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25128296 — Biomarker: Cathepsin S
Type: Pharmacodynamic Biomarker (PDY)
Genes: CTSS
Study 21905981 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 1618244 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23992160 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 14551370 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 9409567 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 2442558 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2442558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27099270 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 22503720 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22503720 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 2891798 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 28473464 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 16683215 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16683215 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11467090 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 7833222 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17171860 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 28258664 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28258664 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 28258664 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25486333 — Biomarker: SLCO1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 10949722 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 8766611 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17541072 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 31653603 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 23589556 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23589556 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 19581850 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19581850 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12098150 — Biomarker: SERPINB6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINB6; PI6; PTI
Study 10023509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29982770 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25671826 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17722824 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30480533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18176118 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 30084882 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8476620 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22710649 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19748210 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 10600919 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 1771945 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27566855 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 17221036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26849923 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23681364 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23681364 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1886157 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 6229567 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 19497197 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 7541448 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2473880 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 19573556 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19573556 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17380560 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 14679114 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19719910 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12223140 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11557486 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31924955 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31924955 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25620034 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17403707 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14978366 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2503945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30995312 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 26066063 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26066063 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23862647 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 21209124 — Biomarker: HGD mRNA
Type: Predictive Biomarker (PRD)
Genes: HGD; HGO
Study 18305082 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 18305082 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18305082 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 18305082 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 12207105 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 26471311 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 12964946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27855097 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 29343076 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29343076 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 22351696 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15237710 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 15237710 — Biomarker: GHR mRNA
Type: Predictive Biomarker (PRD)
Genes: GHR
Study 9862573 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21635359 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 15194910 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11897984 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 11897984 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17717132 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15039514 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22406074 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 28057126 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 28057126 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21574984 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12698776 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29155861 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 29155861 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9059545 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 9059545 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 9059545 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 16331118 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1281442 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17179910 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 9797644 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 22607734 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 21851643 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21851643 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19148642 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19148642 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17214932 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17214932 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17214932 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 17214932 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 24595568 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC
Study 24595568 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 24595568 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30407328 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12957433 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8862762 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 1340807 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17577134 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17577134 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17577134 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 11880130 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 2277574 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 21489817 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15033254 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 29118031 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 29118031 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21636566 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21636566 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21636566 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 10651259 — Biomarker: UCP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP2; SLC25A8
Study 31421670 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 31421670 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 27893184 — Biomarker: CACNA1C mRNA
Type: Predictive Biomarker (PRD)
Genes: CACNA1C; CACH2; CACN2; CACNL1A1; CCHL1A1
Study 23880960 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 17967584 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17967584 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25817289 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 25817289 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22082795 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22082795 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 22695134 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18946298 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12824967 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 11938811 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 11938811 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29242281 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29242281 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 25522424 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 25522424 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 17353132 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 16288118 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 7734138 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23471234 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9100162 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8261692 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3511691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30041437 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 27936999 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25166215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15383088 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15383088 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 30001179 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study 24318863 — Biomarker: ERCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC2; XPD; XPDC
Study 24318863 — Biomarker: GSTP1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: GSTP
Study 2472826 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 17536122 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17536122 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29843755 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23418958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22029856 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 22029856 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 22029856 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 1351888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6584561 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29031390 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 20880729 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20880729 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 12390994 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 22985580 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11789395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11789395 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2442551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28899914 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22039086 — Biomarker: MAX mRNA
Type: Predictive Biomarker (PRD)
Genes: MAX; BHLHD4
Study 9532410 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31576915 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 7486614 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 964056 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 19667268 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 19667268 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 10806696 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1996187 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6434435 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 29524476 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 23307827 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 16855141 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 21533995 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 12514658 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12514658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8698756 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17628232 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29147969 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29147969 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 29147969 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 29147969 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29147969 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29147969 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 24742322 — Biomarker: INPP5D mRNA
Type: Predictive Biomarker (PRD)
Genes: INPP5D; SHIP; SHIP1
Study 20805433 — Biomarker: SMPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMPD1; ASM
Study 8866698 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 6438014 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25272965 — Biomarker: PICALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PICALM; CALM
Study 24136890 — Biomarker: SPARC mRNA
Type: Predictive Biomarker (PRD)
Genes: SPARC; ON
Study 16617400 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 24595632 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22866767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12392586 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 10543321 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2125243 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26233594 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 11996943 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15840675 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15840675 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 29233615 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29233615 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21357381 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 15253741 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341