AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 19083390 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19083390 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12865483 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30786754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29856004 — Biomarker: CXCR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR2; IL8RB
Study 15714423 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9484756 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 7648765 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 2541637 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25956401 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25956401 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25956401 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25956401 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15351795 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11018853 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20388647 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 12714091 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12714091 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25900347 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 24169061 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 21507143 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 17297625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11484097 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9495424 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28678853 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19383112 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16704575 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 30110579 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 30110579 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 26671747 — Biomarker: CDKN2A mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2A; CDKN2; MTS1
Study 26671747 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 26671747 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 21349483 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2667745 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31282592 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9244228 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16797280 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 10701823 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24139558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22337227 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18580613 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15955616 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 31704188 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17666194 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17666194 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 11084548 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9487348 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8368227 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31732742 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23969513 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19891902 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 17805238 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9734613 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28263203 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23844093 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 23844093 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21696359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3388405 — Biomarker: CPD mRNA
Type: Predictive Biomarker (PRD)
Genes: CPD
Study 31135225 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12580930 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 6908098 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31838445 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 6125193 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23106658 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15124243 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 7898332 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2796855 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28521717 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23881421 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 15028823 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9124619 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8129541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24942709 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22166162 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 7769295 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 7769295 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study 94616 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 94616 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 6195479 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19833819 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 40798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31671219 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 31671219 — Biomarker: STAMBP mRNA
Type: Predictive Biomarker (PRD)
Genes: STAMBP; AMSH
Study 31671219 — Biomarker: AXIN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AXIN1; AXIN
Study 31671219 — Biomarker: CASP8 mRNA
Type: Predictive Biomarker (PRD)
Genes: CASP8; MCH5
Study 31671219 — Biomarker: CD6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD6
Study 31671219 — Biomarker: CDCP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDCP1; TRASK; UNQ2486/PRO5773
Study 31671219 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 31671219 — Biomarker: SLAMF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLAMF1; SLAM
Study 31671219 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 31671219 — Biomarker: CSF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF1
Study 31671219 — Biomarker: CXCL6 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL6; GCP2; SCYB6
Study 19785568 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19785568 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31402538 — Biomarker: NR1H4 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study 31402538 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27658659 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 27658659 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21568075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8851570 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24939671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27006237 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27006237 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 28671879 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27112612 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 94638 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28153005 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26616798 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 9580646 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 28466507 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 18173345 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 14691773 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 28662152 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 26425078 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21543543 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16959618 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15221622 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 3677365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26809111 — Biomarker: ADAM17 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM17; CSVP; TACE
Study 17287681 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 2851414 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24168107 — Biomarker: SLC22A4
Type: Predictive Biomarker (PRD)
Genes: OCTN1; MGC34546
Study 20004464 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28513877 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22003288 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 22003288 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22003288 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 18584198 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18584198 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 17310820 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25853876 — Biomarker: BTC mRNA
Type: Predictive Biomarker (PRD)
Genes: BTC
Study 29070467 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29070467 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29070467 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22254404 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 16702490 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7540231 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 7540231 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21499182 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19932775 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26455498 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 26455498 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 3894101 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 12819556 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10494188 — Biomarker: RTEL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RTEL1; C20orf41; KIAA1088; NHL
Study 21066889 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21066889 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21066889 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11228175 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11228175 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24078198 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17510682 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17510682 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10076899 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 10076899 — Biomarker: F7 mRNA
Type: Predictive Biomarker (PRD)
Genes: F7
Study 28941314 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 9663913 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7923656 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30088425 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 24150547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12852711 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 26372680 — Biomarker: CHIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHIT1
Study 26372680 — Biomarker: Chitinase-3-like protein 1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: CHI3L1
Study 21149331 — Biomarker: SFRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SFRP1; FRP; FRP1; SARP2
Study 21149331 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17353040 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12186498 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12186498 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 18420939 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17585662 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 16304265 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 6340415 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10911006 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 1330127 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 31024557 — Biomarker: TLR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR3
Study 31024557 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31024557 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 12187500 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7529484 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27006512 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25073015 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 26936842 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 21360202 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31630153 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 31630153 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 31630153 — Biomarker: Cytokine ML-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IL17F
Study 31630153 — Biomarker: TLR9
Type: Predictive Biomarker (PRD)
Genes: CD289
Study 23343906 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3056476 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 21729518 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18834457 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17209788 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 9728228 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 9728228 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16583234 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27401475 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16216721 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 1981022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26386540 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 23714362 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15657502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7476342 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31605877 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 14555565 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 22982903 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22982903 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16786754 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23848167 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23848167 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17585029 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 17585029 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17585029 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 8922769 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3892345 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30219843 — Biomarker: ACTG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACTG1; ACTG
Study 19125989 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31197264 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31197264 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31197264 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18708148 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 26158769 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18296978 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15110129 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11346861 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9212042 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9212042 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 7963146 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14631328 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 28745999 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26287338 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19906454 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 19906454 — Biomarker: CASP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CASP3; CPP32
Study 19906454 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 1629885 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1629885 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18756970 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18756970 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18756970 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 15247556 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 15247556 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 15247556 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 11243418 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29423947 — Biomarker: CCR3 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CCR3; CMKBR3
Study 29423947 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 19713947 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30082170 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26920573 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27950535 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27950535 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 14551182 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 15702134 — Biomarker: GABRA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GABRA2
Study 28872752 — Biomarker: SMPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMPD1; ASM
Study 22158066 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20120778 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20120778 — Biomarker: Urinary total protein
Type: Safety Biomarker (SAF)
Study 20120778 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 20120778 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)