AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 27225610 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25040793 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25040793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11039131 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 20448462 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20448462 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 18702958 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7980596 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 7980596 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 22240263 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12480510 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 14747232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25591054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16761891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9117220 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 23744329 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23744329 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23744329 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17490568 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 7986708 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 31496653 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31496653 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31496653 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31496653 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31496653 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 17109337 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15009462 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15009462 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11571437 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 11571437 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9669720 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9669720 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25166440 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 3046631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27166622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20868965 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20868965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1095159 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25849627 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25849627 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 21562066 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21562066 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 10866913 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3511308 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22398360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10483942 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30930429 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24705337 — Biomarker: MEST mRNA
Type: Predictive Biomarker (PRD)
Genes: MEST; PEG1
Study 2826100 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30509224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23999999 — Biomarker: miR-22
Type: Safety Biomarker (SAF)
Genes: MIR22
Study 22624833 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 22624833 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 20592293 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 12833187 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 8909662 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24478323 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 12871893 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8793701 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25486369 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31543373 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 23812551 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19737620 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17403721 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 17403721 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17403721 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 9398110 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9398110 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 20588187 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9236347 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 27904973 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 23690996 — Biomarker: IRF7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRF7
Study 23690996 — Biomarker: IFIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFIT1; G10P1; IFI56; IFNAI1; ISG56
Study 23690996 — Biomarker: IFIT5 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFIT5; ISG58; RI58
Study 23690996 — Biomarker: OASL mRNA
Type: Predictive Biomarker (PRD)
Genes: OASL; TRIP14
Study 23690996 — Biomarker: CLC mRNA
Type: Predictive Biomarker (PRD)
Genes: CLC; LGALS10; LGALS10A
Study 23690996 — Biomarker: PSMB9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSMB9; LMP2; PSMB6i; RING12
Study 23690996 — Biomarker: HERC5 mRNA
Type: Predictive Biomarker (PRD)
Genes: HERC5; CEB1; CEBP1
Study 23690996 — Biomarker: CCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR1; CMKBR1; CMKR1; SCYAR1
Study 23690996 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 23690996 — Biomarker: MS4A4A mRNA
Type: Predictive Biomarker (PRD)
Genes: MS4A4A; 4SPAN1; CD20L1; MS4A4; HDCME31P
Study 23690996 — Biomarker: XAF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: XAF1; BIRC4BP; XIAPAF1
Study 12925845 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 9411502 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28770549 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 31335937 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22271474 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15226321 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 3207437 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10513041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8558158 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 24364085 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11170060 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23275352 — Biomarker: AZGP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AZGP1; ZAG; ZNGP1
Study 21986347 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30688550 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12741429 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 11345288 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 11345288 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11345288 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 7526102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3299004 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 3299004 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 28917688 — Biomarker: SHD mRNA
Type: Predictive Biomarker (PRD)
Genes: SHD
Study 28917688 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23713213 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20500100 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20500100 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20500100 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17825587 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 16815486 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30217374 — Biomarker: BLK mRNA
Type: Predictive Biomarker (PRD)
Genes: BLK
Study 24894410 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 20625111 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15793606 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22674146 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16214025 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31880343 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 18716688 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15314393 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 8287567 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 8287567 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 2882294 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 24079037 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20076856 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 20076856 — Biomarker: TOB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TOB1; TOB; TROB1
Study 18194028 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 16387583 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 15057400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24669750 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 16294264 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12412806 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21689142 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 12742999 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 24133627 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 21367625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21367625 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16508253 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 23299530 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23299530 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19900491 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21482091 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12919709 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9041463 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9041463 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 9041463 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 28329789 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 28329789 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 7470200 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11409458 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7886407 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3525768 — Biomarker: VCP mRNA
Type: Predictive Biomarker (PRD)
Genes: VCP
Study 23690342 — Biomarker: SIGLEC12 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIGLEC12; SIGLECL1; SLG; UNQ9215/PRO34042
Study 23690342 — Biomarker: A1BG mRNA
Type: Predictive Biomarker (PRD)
Genes: A1BG
Study 23690342 — Biomarker: Coagulation factor Va
Type: Safety Biomarker (SAF)
Genes: F5
Study 20427734 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20427734 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20427734 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 12825855 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29939261 — Biomarker: OMD mRNA
Type: Predictive Biomarker (PRD)
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 29939261 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 22303592 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9068554 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 16397516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11069371 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 25633713 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25633713 — Biomarker: CLEC9A mRNA
Type: Predictive Biomarker (PRD)
Genes: CLEC9A; UNQ9341/PRO34046
Study 18239661 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18239661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28477718 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17116941 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 9542575 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27505322 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27505322 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 18989992 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 1580285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6342352 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30833491 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15063813 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31083232 — Biomarker: NFKB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NFKB2; LYT10
Study 31083232 — Biomarker: RELA mRNA
Type: Predictive Biomarker (PRD)
Genes: RELA; NFKB3
Study 31083232 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 31083232 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31083232 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30207526 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20139674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10348358 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26313229 — Biomarker: Proliferation marker protein Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67
Study 19947264 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17711715 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15144473 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 9646001 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 28292282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23463651 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23463651 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19064281 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 19064281 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 10844622 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10844622 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29334721 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12445840 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 6428171 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31983031 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 19415350 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 17000910 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30379212 — Biomarker: SLA mRNA
Type: Predictive Biomarker (PRD)
Genes: SLA; SLAP; SLAP1
Study 22914465 — Biomarker: PGP mRNA
Type: Predictive Biomarker (PRD)
Genes: PGP
Study 31060367 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 28826290 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 22629163 — Biomarker: LGSN mRNA
Type: Predictive Biomarker (PRD)
Genes: LGSN; GLULD1; LGS
Study 31742903 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 28564564 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17479860 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 17479860 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17479860 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 7995864 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 7995864 — Biomarker: SAT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT2; SSAT2
Study 17068305 — Biomarker: TPI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPI1; TPI
Study 17068305 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25456979 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 16537575 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 16537575 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16537575 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29716436 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 29716436 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 17646272 — Biomarker: SOD2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SOD2
Study 12390315 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2184945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14996880 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 8195450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17181436 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3536890 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 25148234 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16320099 — Biomarker: SLC38A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 12439210 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12439210 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22727707 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 15184351 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15184351 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15184351 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 15184351 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1