AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 22029963 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22029963 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 30422319 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 22791766 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17586184 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 15642679 — Biomarker: IHH mRNA
Type: Predictive Biomarker (PRD)
Genes: IHH
Study 15642679 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 15463835 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 15463835 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8950783 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8950783 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 30646822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21175274 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 15108766 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 15108766 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11411908 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31448116 — Biomarker: MSR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MSR1; SCARA1
Study 31448116 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 31448116 — Biomarker: FADS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS1; FADSD5
Study 31448116 — Biomarker: INSIG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: INSIG1
Study 31448116 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 31448116 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 31448116 — Biomarker: ABCG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG1; ABC8; WHT1
Study 24266299 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21410733 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 14633563 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30261738 — Biomarker: PTBP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTBP2; NPTB; PTB; PTBLP
Study 19124398 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9451066 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 9451066 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2527473 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 2527473 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31943297 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 31943297 — Biomarker: STAT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT4
Study 10676687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29108664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26545726 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 26545726 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20513863 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 8227449 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 3762014 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25657183 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21508090 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 19540137 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 16282699 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16282699 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11287080 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 11287080 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11287080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27665225 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 27665225 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 24643340 — Biomarker: Clusterin
Type: Safety Biomarker (SAF)
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 24643340 — Biomarker: CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR1; C3BR
Study 24643340 — Biomarker: PICALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PICALM; CALM
Study 24643340 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 16020407 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16020407 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16020407 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12501950 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 12501950 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15951873 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10068580 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10068580 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28030716 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26340807 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 23582742 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 1764497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7123111 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31638491 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 31638491 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25541333 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24285582 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19532100 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19532100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17431603 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 11354304 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 26514192 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 26514192 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18082233 — Biomarker: DHFR mRNA
Type: Predictive Biomarker (PRD)
Genes: DHFR
Study 18082233 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 3739582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27126957 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27126957 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27126957 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22520791 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19643310 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19643310 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7753739 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29615077 — Biomarker: UBC mRNA
Type: Predictive Biomarker (PRD)
Genes: UBC
Study 29615077 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 18793361 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 1732896 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 16326671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22367128 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 18952211 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21036889 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8952810 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25025854 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 20801567 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20801567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27626136 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 15564721 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 8747407 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 2233115 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15226683 — Biomarker: TGFB1
Type: Safety Biomarker (SAF)
Genes: CED; TGFbeta
Study 15226683 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 15226683 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 9684909 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9684909 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 31226684 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study 29157765 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12421482 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 7854376 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24915175 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18085138 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 14967451 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 30707138 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27004462 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27004462 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17673811 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 29982728 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 14521597 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2442543 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2442543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27321596 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 27321596 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 27321596 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 27321596 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 23873670 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19762071 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 17684522 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 15968885 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 15968885 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 11307227 — Biomarker: TP53INP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TP53INP1; P53DINP1; SIP
Study 8402734 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 16507374 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 10593375 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 10593375 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28028984 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25493120 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 21655909 — Biomarker: NANOS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS1; NOS1
Study 21655909 — Biomarker: NANOS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS3; NOS3
Study 21655909 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21655909 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 11862965 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 7617349 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 334315 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 31385001 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 19188550 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 26254752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20701479 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15030300 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 22674470 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 17416453 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 9699568 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2760214 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 20971975 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9726444 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15514193 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 8497284 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28859868 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28859868 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16446313 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30298556 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24962875 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 27368672 — Biomarker: Sodium/hydrogen exchanger 3
Type: Safety Biomarker (SAF)
Genes: SLC9A3; NHE3
Study 26574871 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26574871 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 26574871 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19034332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16819567 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 16819567 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14600515 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10898421 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 8882962 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 28026777 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 16948861 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9139271 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 9139271 — Biomarker: HES1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HES1; BHLHB39; HL; HRY
Study 6291832 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6291832 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28581397 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 21925996 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22768174 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19180484 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 21944697 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19583930 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8311599 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31574878 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 27789297 — Biomarker: M6PR mRNA
Type: Predictive Biomarker (PRD)
Genes: M6PR; MPR46; MPRD
Study 11434165 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 8299318 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31670603 — Biomarker: UCP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP1; SLC25A7; UCP
Study 11522187 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11522187 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11192866 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 11192866 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9452280 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 30443924 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6294699 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 10587334 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9193426 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30037778 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 26540028 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 11783322 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31857431 — Biomarker: WEE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WEE1
Study 26841085 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23782950 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 23782950 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 16772525 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9366499 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 18227177 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6361988 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 3382764 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 30467695 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28460246 — Biomarker: COPE mRNA
Type: Predictive Biomarker (PRD)
Genes: COPE
Study 15539971 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18242413 — Biomarker: Platelet count response
Type: Surrogate Endpoint (SUR)
Study 10199862 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30239421 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 21677052 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19434759 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 1620810 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1620810 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24760382 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16250265 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 16250265 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 16250265 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12020980 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 12020980 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26874974 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24182347 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24182347 — Biomarker: IL21
Type: Predictive Biomarker (PRD)
Genes: Za11; IL-21
Study 22373720 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 20560112 — Biomarker: KLRK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRK1; D12S2489E; NKG2D
Study 10470387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31274187 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 31274187 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31274187 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 25756064 — Biomarker: DOCK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DOCK3; KIAA0299; MOCA
Study 11248761 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7750598 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 27866454 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 25412116 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 25412116 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19188184 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 19188184 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4