AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 14634680 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 21441812 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 15513446 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 28271568 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28271568 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18931625 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16820341 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 16820341 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21557134 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10964582 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8619212 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8619212 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3872001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22929437 — Biomarker: SLC2A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A1; GLUT1
Study 20059663 — Biomarker: SEMG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEMG1; SEMG
Study 15470483 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11824861 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8618108 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 26044854 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC
Study 26044854 — Biomarker: CCL22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 17925592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10728939 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 2027357 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 6161557 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 21505892 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 12920975 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12920975 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 12920975 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7498858 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26809868 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23244537 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23244537 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17932317 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28851407 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22021620 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11733695 — Biomarker: Lysosomal acid glucosylceramidase
Type: Pharmacodynamic Biomarker (PDY)
Genes: GBA1; GBA; GC; GLUC
Study 24548574 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 24548574 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 21801467 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8671790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17469154 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 7827929 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7827929 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 23315144 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23315144 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19724980 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11822785 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31891746 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31891746 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 31891746 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 31220630 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 31679055 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21748205 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16951472 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12730811 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 8952125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2009249 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31732852 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 28248037 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 16878325 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 16878325 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 16878325 — Biomarker: CLEC4D mRNA
Type: Predictive Biomarker (PRD)
Genes: CLEC4D; CLECSF8; MCL
Study 16878325 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 29135482 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 26684822 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10652036 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10652036 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10652036 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10652036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25220196 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7305656 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28975661 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25380675 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25380675 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 8947787 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20391513 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2166253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10372612 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 1696663 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1696663 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 1696663 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23734617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21894807 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16776752 — Biomarker: NPL mRNA
Type: Predictive Biomarker (PRD)
Genes: NPL; C1orf13
Study 11426092 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10925339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6613138 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 21822678 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2476604 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29961888 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 29961888 — Biomarker: IGFBP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP7; MAC25; PSF
Study 29961888 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24816760 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24099796 — Biomarker: BBC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BBC3; PUMA
Study 24099796 — Biomarker: CHEK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHEK2; CDS1; CHK2; RAD53
Study 24099796 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 10950401 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3537783 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22388001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11820861 — Biomarker: ALAD mRNA
Type: Predictive Biomarker (PRD)
Genes: ALAD
Study 31222759 — Biomarker: DDC mRNA
Type: Predictive Biomarker (PRD)
Genes: DDC; AADC
Study 31222759 — Biomarker: ALDH7A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH7A1; ATQ1
Study 7516450 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 14969070 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31062389 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 11597664 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 11597664 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 3328992 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 23143621 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9952147 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8649928 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 28133708 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 21816087 — Biomarker: MAF mRNA
Type: Predictive Biomarker (PRD)
Genes: MAF
Study 19622756 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17317827 — Biomarker: TIMP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TIMP3
Study 17317827 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 17317827 — Biomarker: DAPK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DAPK1; DAPK
Study 17317827 — Biomarker: RASSF1A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: RASSF1; NORE2A; REH3P21; RDA32; 123F2
Study 11435053 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 9512323 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8037411 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31958336 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 30477915 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9049584 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 8349330 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30554581 — Biomarker: SOX9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOX9
Study 30554581 — Biomarker: BAX mRNA
Type: Predictive Biomarker (PRD)
Genes: BAX; BCL2L4
Study 30554581 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30554581 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 30554581 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16115360 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 16115360 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7009908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3629186 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 3629186 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study 26198758 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 26198758 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21156931 — Biomarker: CACNB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CACNB2; CACNLB2; MYSB
Study 16814412 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 10519502 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31174055 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31174055 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22432725 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22432725 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3159346 — Biomarker: IFT122 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFT122; SPG; WDR10; WDR140
Study 9013366 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26238672 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17464552 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11673814 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16507186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29572676 — Biomarker: Calgranulin B
Type: Predictive Biomarker (PRD)
Genes: S100A9; CAGB; CFAG; MRP14
Study 29572676 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 29572676 — Biomarker: DEFB4A mRNA
Type: Predictive Biomarker (PRD)
Genes: DEFB4A; DEFB102; DEFB2; DEFB4; DEFB4B
Study 29572676 — Biomarker: RSAD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RSAD2; CIG5
Study 29572676 — Biomarker: CAMP mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMP; CAP18; FALL39; HSD26
Study 29572676 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 24059443 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 31551154 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31551154 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 26134837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23786760 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16835670 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16835670 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21587283 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18423697 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10711705 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 1376845 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3888386 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 21329022 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21329022 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 17342992 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17342992 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17941026 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28625234 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 16467101 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 16467101 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16467101 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 820622 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 25993590 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23666746 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 21863638 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17326152 — Biomarker: C-X-C motif chemokine 11
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 17326152 — Biomarker: CXCR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR3; GPR9
Study 30218227 — Biomarker: FGG mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGG; PRO2061
Study 27139726 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24622121 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 12566834 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7828353 — Biomarker: Urine free cortisol
Type: Surrogate Endpoint (SUR)
Study 23168172 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18374542 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 17768157 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12701260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26450146 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20093075 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 15613431 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10074017 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17924016 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11518851 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9778268 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9778268 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9778268 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11602814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 335572 — Biomarker: TMPRSS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMPRSS13; MSP; TMPRSS11
Study 25538270 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17873301 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 7908624 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 2892388 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17876336 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17876336 — Biomarker: KIT
Type: Predictive Biomarker (PRD)
Genes: CD117; SCFR; C-Kit
Study 28862513 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 12009719 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28438283 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23212720 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19454737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19454737 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3121836 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25391865 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 23868011 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 16015270 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8453956 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29228315 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 29228315 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29228315 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 27128532 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 27128532 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 22623230 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 20736987 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 26720308 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 17299059 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15214257 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 11225566 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 2571460 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 29458056 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 29458056 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 22875102 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 22875102 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22875102 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 28369670 — Biomarker: MMD mRNA
Type: Predictive Biomarker (PRD)
Genes: MMD; PAQR11
Study 20301883 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 27287699 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 27287699 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18382839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14727988 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)