AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 1794215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1794215 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22727431 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20634298 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 7772352 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28961838 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10455343 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 10455343 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28412747 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 28412747 — Biomarker: SELENOP mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENOP; SELP; SEPP1
Study 9599737 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 2732164 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28903775 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26002049 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26002049 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26002049 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21373802 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 21373802 — Biomarker: STC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STC1; STC
Study 21373802 — Biomarker: NTS mRNA
Type: Predictive Biomarker (PRD)
Genes: NTS
Study 3316303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3316303 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 3316303 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 18588355 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 18588355 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18588355 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16630994 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16630994 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16630994 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10881952 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 1294606 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 30168266 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 26907090 — Biomarker: FUT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FUT2; SEC2
Study 24151017 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3392233 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31008870 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29248107 — Biomarker: RPSA mRNA
Type: Predictive Biomarker (PRD)
Genes: RPSA; LAMBR; LAMR1
Study 26980809 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 28365440 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 14674148 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31259655 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 22939114 — Biomarker: TRIM63 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 22939114 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 21029339 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29663513 — Biomarker: GRK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRK5; GPRK5
Study 29663513 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 24951609 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9856371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9856371 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 38214 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31237450 — Biomarker: Cyclin-dependent kinase inhibitor 1
Type: Safety Biomarker (SAF)
Genes: CDKN1A
Study 31237450 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 26130237 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 17913695 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 11281339 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11281339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30929570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21515479 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19637348 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study 11570021 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18340390 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12665170 — Biomarker: HPN mRNA
Type: Predictive Biomarker (PRD)
Genes: HPN; TMPRSS1
Study 31540867 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 25751232 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25751232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21325108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12707979 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 30710837 — Biomarker: Sclerostin
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: SOST; UNQ2976/PRO7455/PRO7476
Study 30710837 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 30710837 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19334042 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 8122957 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 8122957 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2521863 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 9883 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25652389 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 19222404 — Biomarker: CXADR mRNA
Type: Predictive Biomarker (PRD)
Genes: CXADR; CAR
Study 1466618 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11075309 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28496022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24521993 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 21720426 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11448018 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23383690 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23383690 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 23383690 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 19506112 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19506112 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 17709433 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11485526 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 11485526 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11485526 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 9724277 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30333054 — Biomarker: POR mRNA
Type: Predictive Biomarker (PRD)
Genes: POR; CYPOR
Study 28375706 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28375706 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 8900987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31489410 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 25866155 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25866155 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25866155 — Biomarker: Macrophage inflammatory protein 1-alpha
Type: Monitoring Biomarker (MOI)
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 24525232 — Biomarker: FGFR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR3; JTK4
Study 24525232 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 24525232 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22774398 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study 24178584 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 24178584 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 20207825 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21930596 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21930596 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 16426275 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 15561035 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 3297124 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 3297124 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3297124 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 3297124 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3036724 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 14985996 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 10095796 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10095796 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10095796 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 8800885 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 14560186 — Biomarker: BAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAK1; BAK; BCL2L7; CDN1
Study 8729308 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30659292 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 25131184 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 25131184 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 1377741 — Biomarker: PRCP mRNA
Type: Predictive Biomarker (PRD)
Genes: PRCP; PCP
Study 31578954 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23698590 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8985298 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 27526120 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23974954 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20537746 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 8706481 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17667569 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26386799 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17703100 — Biomarker: ACP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACP1
Study 16794028 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 9058224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8382840 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8382840 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 14626378 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8636581 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1336356 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1336356 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 2866786 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29206782 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 14712987 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14712987 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1643806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23746558 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 16639484 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11834533 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 11834533 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7527493 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25579006 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19164343 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 2108885 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 518076 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19843321 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20865841 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15671427 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1905960 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29690736 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26890974 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 26890974 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 26890974 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17472600 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 25482871 — Biomarker: Proliferation marker protein Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67
Study 25482871 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC
Study 25482871 — Biomarker: CCL18 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 25482871 — Biomarker: CCL22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 25482871 — Biomarker: CCL26 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL26; SCYA26; UNQ216/PRO242
Study 25482871 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 22740508 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 10551383 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28727231 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28727231 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9412549 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 7528360 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31253213 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 19737278 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 28025964 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 24709775 — Biomarker: TLR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR3
Study 24709775 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24709775 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 14602761 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14602761 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10744147 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12500073 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 11303310 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 29220105 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 29220105 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 29220105 — Biomarker: Cathepsin S
Type: Pharmacodynamic Biomarker (PDY)
Genes: CTSS
Study 29085004 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 21338276 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30918134 — Biomarker: AZGP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AZGP1; ZAG; ZNGP1
Study 17121211 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28598590 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 25100359 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25100359 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25100359 — Biomarker: TNFRSF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1A; TNFAR; TNFR1
Study 25100359 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17586413 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17586413 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10533793 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 1676238 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29780293 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29780293 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 29780293 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 27059880 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 24655586 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 1970108 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 7425360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22012805 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 22012805 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 22012805 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19571161 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19571161 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19571161 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11347834 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11347834 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 8255974 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27486125 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17977950 — Biomarker: TBC1D4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TBC1D4; AS160; KIAA0603
Study 17977950 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 19709417 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 2972158 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2972158 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 19303793 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 15252908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15252908 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26208341 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 26208341 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26208341 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 19952817 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 12968982 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 9200808 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9200808 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8258267 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 16024973 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 3913379 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29901507 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2960296 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 27352414 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 24708338 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 21569996 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL