AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 11728258 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16877536 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9088591 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 29860917 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29860917 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 26280319 — Biomarker: Growth/differentiation factor 8
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: MSTN; GDF8
Study 26280319 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26280319 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 22261295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20417659 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 12220692 — Biomarker: ACSL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACSL1; FACL1; FACL2; LACS; LACS1; LACS2
Study 31290715 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24385202 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15556056 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15556056 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 9625848 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 7877082 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24608200 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 10210973 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2196060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8567517 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8567517 — Biomarker: TMEM37 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMEM37; PR
Study 19840529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9863541 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 8574712 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 23469599 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 4014191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27356102 — Biomarker: TEF mRNA
Type: Predictive Biomarker (PRD)
Genes: TEF; KIAA1655
Study 24204790 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 18434733 — Biomarker: RAPGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 20048486 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20048486 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11560366 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 11560366 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 17178796 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 7986518 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7986518 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23099620 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 23099620 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 23099620 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 29996476 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16075984 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9883435 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 2195734 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 154624 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28158981 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26232911 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26232911 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21427431 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12423709 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30554073 — Biomarker: T-cell specific protein RANTES
Type: Safety Biomarker (SAF)
Genes: CCL5; D17S136E; SCYA5
Study 30554073 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 30554073 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 22859343 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22859343 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19958854 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 19958854 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15207957 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 956798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22761006 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 22165113 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 16801465 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9082341 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1797696 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1797696 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31419271 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29228436 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29228436 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29228436 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26435087 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 26435087 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26435087 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 22933498 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 17890171 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15337535 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 21034274 — Biomarker: LARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LARS1; KIAA1352; LARS
Study 8712391 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8712391 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 8712391 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20636227 — Biomarker: RYR1
Type: Safety Biomarker (SAF)
Genes: RYR; PPP1R137
Study 14528656 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21526663 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9931171 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2175139 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 18602635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10814600 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29796596 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 26802087 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26802087 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 26802087 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 15911902 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12409329 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 1975746 — Biomarker: TEP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TEP1; TLP1; TP1
Study 1975746 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31987116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31987116 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30367257 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23405158 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21941411 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21941411 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 28627349 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21448267 — Biomarker: PCSK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK5; PC5; PC6
Study 22222469 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11841067 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21050549 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 21050549 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 21050549 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 17698724 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15703502 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1695308 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30971174 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30971174 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27230030 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22142348 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19197536 — Biomarker: TGM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TGM1; KTG
Study 19197536 — Biomarker: CYP26A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP26A1; CYP26; P450RAI1
Study 19197536 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19197536 — Biomarker: KRT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KRT2; KRT2A; KRT2E
Study 19197536 — Biomarker: KRT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: KRT4; CYK4
Study 14601047 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study 30679232 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 30679232 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 30679232 — Biomarker: MAP2K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K1; MEK1; PRKMK1
Study 30679232 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 28199463 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 20126902 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20126902 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 17003306 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7770136 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26882609 — Biomarker: SP9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP9
Study 26882609 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 11958590 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 11958590 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 30536047 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17621237 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12381833 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 10022995 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2283650 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2283650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29541862 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 29541862 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29757889 — Biomarker: TNFRSF9 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF9; CD137; ILA
Study 29757889 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 29757889 — Biomarker: Tumor-infiltrating lymphocyte
Type: Predictive Biomarker (PRD)
Study 10096462 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19632524 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7818835 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2977328 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29127458 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 29127458 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 29127458 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 26443242 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 8101772 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8101772 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 3565301 — Biomarker: PAFAH1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study 28959471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28959471 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23047595 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16484911 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 10669333 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7067184 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21764840 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 19167143 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 3042841 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 25402372 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 25402372 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9364693 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17923653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16275486 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7598920 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7598920 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 7598920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31129929 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 26480548 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 26480548 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 15090391 — Biomarker: SLMAP mRNA
Type: Predictive Biomarker (PRD)
Genes: SLMAP; KIAA1601; SLAP; UNQ1847/PRO3577
Study 2900901 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 31932932 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 27334418 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26636178 — Biomarker: Cathepsin S
Type: Pharmacodynamic Biomarker (PDY)
Genes: CTSS
Study 30621948 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 30621948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26681684 — Biomarker: PHACTR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PHACTR3; C20orf101; SCAPIN1
Study 25194287 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 25194287 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20573405 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 20573405 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17659926 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17659926 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10362152 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 26921746 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 26921746 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 18678766 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31955410 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31955410 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2079570 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 24740134 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 15129731 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 15129731 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 9697664 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 9697664 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9697664 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 7924122 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 28380474 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 10215436 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26802979 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 21055277 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1329479 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3933397 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8758159 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1949258 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17061673 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21979801 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 15051614 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 11551875 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11551875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30574801 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 23283449 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 8672820 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31833259 — Biomarker: SLC13A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC13A5; NACT
Study 24634631 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 19576353 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19576353 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15128701 — Biomarker: CRHR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CRHR1; CRFR; CRFR1; CRHR
Study 15186523 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16416305 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 16416305 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 8847321 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30121304 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7671893 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 2073911 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27672029 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11896977 — Biomarker: Fibroblast growth factor 10
Type: Predictive Biomarker (PRD)
Genes: FGF10
Study 19493959 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 19493959 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 12086353 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8596098 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 8596098 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1124532 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 1124532 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30691468 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 22079151 — Biomarker: STAR mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAR; STARD1
Study 1971751 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17679132 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3904335 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3904335 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 24484540 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)