AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 28890996 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27356786 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21503940 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12930422 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 18833043 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16186422 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16186422 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16186422 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 2459540 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2459540 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27059056 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16612259 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12759717 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8678327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11742909 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 19038698 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 19038698 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20007824 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 20007824 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 2140375 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 7322956 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22836303 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 22836303 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 371036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15354030 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 15354030 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 15354030 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 10740332 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12942707 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12942707 — Biomarker: MEFV mRNA
Type: Predictive Biomarker (PRD)
Genes: MEFV; MEF; TRIM20
Study 16880426 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 7534423 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 23906899 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 10945312 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22995653 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10391666 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 10391666 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 19436684 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 19436684 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17564015 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17564015 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14757271 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 14757271 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8163718 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27488071 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22781292 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 8796367 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8796367 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 31543976 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 27760089 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 22333882 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12943623 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 8856711 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 29133522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23436264 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20578162 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 30829023 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 22932122 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 22932122 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 26021829 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 26021829 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19651921 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9658370 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 25587056 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 23827726 — Biomarker: APC
Type: Safety Biomarker (SAF)
Genes: DP2; DP3; DP2.5; PPP1R46
Study 15526717 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 15526717 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 9210503 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 29533726 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 25229735 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 25229735 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 22739979 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19617657 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 807698 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 25800753 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23691002 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 15166532 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11479154 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11479154 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11479154 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 30536648 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25015215 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 22311988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22302014 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 16324236 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 12196359 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7616027 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 7616027 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31168657 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23430010 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23430010 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23430010 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9892479 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31816818 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25006707 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10099910 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25483419 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 25483419 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18332608 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18332608 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11127852 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 11127852 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11127852 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 22186694 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 7617237 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12039487 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 12039487 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26521569 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 16897661 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28872917 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25044423 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21542122 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21542122 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 7959083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8880110 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26448506 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26448506 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23897038 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 23897038 — Biomarker: HTR3A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR3A; 5HT3R; HTR3
Study 8623947 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1496838 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6648053 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16635963 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 7297020 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25413958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12869355 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 1958561 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 6765140 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30704260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19217745 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16930803 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 16501636 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 10992963 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 10992963 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1510446 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6649721 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24947080 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 22958958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9454384 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 8216397 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3688417 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28028918 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22954201 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21680153 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 8692536 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 21190603 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16823067 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8923073 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 2936354 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22721929 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18283621 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 10525140 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7725888 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7725888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27736246 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23982033 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17552955 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2184649 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17598652 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30966831 — Biomarker: NES mRNA
Type: Predictive Biomarker (PRD)
Genes: NES; Nbla00170
Study 27751214 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 25732262 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16148617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2347325 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9931168 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28455465 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 26075212 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 26075212 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 10726720 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10726720 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1550016 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1550016 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15964292 — Biomarker: NES mRNA
Type: Predictive Biomarker (PRD)
Genes: NES; Nbla00170
Study 11834427 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9289452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6499703 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 16257098 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study 16257098 — Biomarker: CLSTN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLSTN1; CS1; KIAA0911
Study 16257098 — Biomarker: CLSTN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLSTN2; CS2
Study 11102253 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9285660 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8301153 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 31882375 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31882375 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7516915 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7516915 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 30317947 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30317947 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25758041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22205355 — Biomarker: PRKD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKD1; PKD; PKD1; PRKCM
Study 22205355 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 9233976 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9233976 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28681388 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 22733406 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 9683300 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30586732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23761104 — Biomarker: TAS1R3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAS1R3; T1R3; TR3
Study 23761104 — Biomarker: OMG mRNA
Type: Predictive Biomarker (PRD)
Genes: OMG; OMGP
Study 19407949 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 16529161 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 11387733 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 3914313 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12730120 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 10774461 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10774461 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 21524314 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26686053 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 26686053 — Biomarker: CLC mRNA
Type: Predictive Biomarker (PRD)
Genes: CLC; LGALS10; LGALS10A
Study 22581647 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10196011 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 10196011 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 10196011 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21854162 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19957871 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9327037 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9040027 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 16784930 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16784930 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16784930 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22057829 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 17432690 — Biomarker: GAL3ST1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAL3ST1; CST
Study 29869903 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 29869903 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 29869903 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19092349 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 19092349 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19092349 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 19092349 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19092349 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19092349 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 21237718 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9543281 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 26650626 — Biomarker: ITPA mRNA
Type: Predictive Biomarker (PRD)
Genes: ITPA; C20orf37; My049; OK/SW-cl.9
Study 26650626 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 17701405 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 8653534 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26496331 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 24852180 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 24852180 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24852180 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 24852180 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24852180 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24852180 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 20600033 — Biomarker: HGD mRNA
Type: Predictive Biomarker (PRD)
Genes: HGD; HGO
Study 17850684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15220247 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9209004 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3578544 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19540739 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27334521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21277062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16488953 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15602823 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT