AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 16644641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27596244 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21029001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11176980 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 7967272 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 3480076 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8681490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31136288 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20702114 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 20702114 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31392826 — Biomarker: AATK mRNA
Type: Predictive Biomarker (PRD)
Genes: AATK; AATYK; KIAA0641; LMR1; LMTK1
Study 31392826 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27489178 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 21892200 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 18028134 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 18028134 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 18028134 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 16157451 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 16157451 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 3375576 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8203510 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 31217388 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 30389671 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26243165 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14689405 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31496160 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31496160 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31496160 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19781418 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16769962 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 15579760 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15579760 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15579760 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11416112 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28444742 — Biomarker: Platelet count response
Type: Surrogate Endpoint (SUR)
Study 23174861 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21763463 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15103751 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15103751 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15103751 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15103751 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 15103751 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 15103751 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25631070 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20092179 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 10836772 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 28705993 — Biomarker: FIS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FIS1; TTC11; CGI-135
Study 28705993 — Biomarker: DNM1L mRNA
Type: Predictive Biomarker (PRD)
Genes: DNM1L; DLP1; DRP1
Study 28705993 — Biomarker: BNIP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BNIP3; NIP3
Study 26265643 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 19735180 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19735180 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19735180 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15108768 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 10867596 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 9112067 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 9112067 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9112067 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23689085 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 20629109 — Biomarker: GSN mRNA
Type: Predictive Biomarker (PRD)
Genes: GSN
Study 27254807 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19934029 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3073806 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31496537 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 27822654 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 25471688 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15532340 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29370781 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 26625004 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19636688 — Biomarker: PCLAF mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 19636688 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 11730396 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8695558 — Biomarker: TNFRSF25 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF25; APO3; DDR3; DR3; TNFRSF12; WSL; WSL1; UNQ455/PRO779
Study 892957 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28087069 — Biomarker: miR-122
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR122
Study 22117618 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 19687781 — Biomarker: ABCC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC1; MRP; MRP1
Study 15482167 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 15482167 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9289023 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9289023 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 8513961 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23272529 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 23272529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20660805 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10441602 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 7801862 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30522886 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8231902 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 8231902 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 8231902 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 29105855 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 29105855 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 29105855 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 29105855 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 29105855 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 27259062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9008250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3234469 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29948023 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 22874110 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22874110 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 27449643 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 23469597 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 31232934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17559380 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 1824584 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27187457 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 7711146 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15679068 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12826145 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20163429 — Biomarker: CSF1R mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF1R; FMS
Study 11839628 — Biomarker: ADAM10 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM10; KUZ; MADM
Study 11839628 — Biomarker: ADAM15 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM15; MDC15
Study 2076713 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2076713 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31914241 — Biomarker: Mothers against decapentaplegic homolog 2
Type: Predictive Biomarker (PRD)
Genes: SMAD2; MADH2; MADR2
Study 31914241 — Biomarker: SMAD3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMAD3; MADH3
Study 20210904 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10849894 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 10423609 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27634943 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16013019 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 16013019 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 30130421 — Biomarker: CENPJ mRNA
Type: Predictive Biomarker (PRD)
Genes: CENPJ; CPAP; LAP; LIP1
Study 30130421 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 24962451 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 22879203 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 12507837 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 2058612 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10994859 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20697090 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 16841663 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2272259 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 2272259 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 28699041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25646170 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23824419 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23824419 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11441134 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 373099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31149704 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19255890 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16499636 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 16499636 — Biomarker: CCL22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 16499636 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16499636 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 16499636 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 12921816 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6356865 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29024341 — Biomarker: miR-210
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR210
Study 29024341 — Biomarker: miR-132
Type: Pharmacodynamic Biomarker (PDY)
Genes: MIR132
Study 29024341 — Biomarker: miR-29a
Type: Monitoring Biomarker (MOI)
Genes: MIR29A
Study 29024341 — Biomarker: miR-34a
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR34A
Study 1755876 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6314097 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26853954 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21947680 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12218390 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20433751 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 15947903 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 11961396 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7629406 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20850953 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16957566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16957566 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16957566 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16957566 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11728919 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24942404 — Biomarker: CHEK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHEK1; CHK1
Study 12631138 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12631138 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 27494722 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 11756072 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 25886875 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15492300 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 15492300 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9744770 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31939321 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 30419153 — Biomarker: COPE mRNA
Type: Predictive Biomarker (PRD)
Genes: COPE
Study 31646578 — Biomarker: SOX9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOX9
Study 31646578 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31646578 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 31646578 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27931302 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 15747154 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15747154 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31027889 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29977265 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29977265 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29977265 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 26868369 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 31774956 — Biomarker: AQP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP4
Study 31774956 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15265001 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15265001 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15265001 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24610884 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23609390 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 792490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28381478 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 7940140 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31614418 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26089641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7945575 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 27519791 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27519791 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 27519791 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 27519791 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 20628590 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29100885 — Biomarker: MMP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP7; MPSL1; PUMP1
Study 23234151 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12824094 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12824094 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30099212 — Biomarker: MUL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MUL1; C1orf166; GIDE; MAPL; MULAN; RNF218
Study 23051558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30015069 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21470279 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8225671 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30260748 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 29734881 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 29734881 — Biomarker: Mitochondrial membrane potential
Type: Pharmacodynamic Biomarker (PDY)
Study 17416761 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 15037535 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 15037535 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8871871 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 26480904 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 26480904 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 18811878 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8855804 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 1535876 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6441778 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31919514 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 23937708 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 20086023 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 11265008 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9539069 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9539069 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 5015048 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30824584 — Biomarker: MITF mRNA
Type: Predictive Biomarker (PRD)
Genes: MITF; BHLHE32
Study 30824584 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 30824584 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1