AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 1909692 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 26890969 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 16109577 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 10825039 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 2191876 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 511803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25438232 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23613255 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21713728 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16385331 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12709466 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8610867 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8610867 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31451009 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31451009 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 31451009 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22682298 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29350603 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22241259 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 18279056 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 12520528 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8968175 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12773075 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12773075 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27417982 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12585781 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30465630 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19698013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1553580 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29967045 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22205149 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 10235511 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28966304 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 14693611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9526939 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9526939 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31397128 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 10426879 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7056271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28533100 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 27914656 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 18332454 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 16105530 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 11834648 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26345405 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25761430 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 10929769 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10929769 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 10929769 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 25964246 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25964246 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25964246 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 9659302 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 31219254 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23585901 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 25332476 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 20411443 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17506591 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12419084 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31133052 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22057473 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 11960266 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11960266 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 2698902 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20830241 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16639473 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 16639473 — Biomarker: HADH mRNA
Type: Predictive Biomarker (PRD)
Genes: HADH; HAD; HAD1; HADHSC; SCHAD
Study 28548024 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 9289451 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30127595 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17803435 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28664036 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 28664036 — Biomarker: TRAPPC9 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 15361758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2906345 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25137843 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7392895 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17473654 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31042581 — Biomarker: STAT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT4
Study 31042581 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 29494476 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24858952 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18328014 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10100079 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6095635 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25251800 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22265215 — Biomarker: DRAM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRAM1; DRAM
Study 18377783 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18377783 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15814545 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12168963 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30641707 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23252768 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 21069358 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 19028707 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19028707 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10551636 — Biomarker: RRAD mRNA
Type: Predictive Biomarker (PRD)
Genes: RRAD; RAD
Study 8565028 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8565028 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 29309486 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29309486 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17344493 — Biomarker: RGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RGL1; KIAA0959; RGL
Study 26826565 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 24628042 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 10029962 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7574780 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 23081753 — Biomarker: BOC mRNA
Type: Predictive Biomarker (PRD)
Genes: BOC; UNQ604/PRO1190
Study 23081753 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 15253884 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 15253884 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8220974 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19378437 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19378437 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8868311 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 23418668 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 17697551 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17697551 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 9730356 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 29208626 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 29208626 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 25876344 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 18332449 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12914790 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 12914790 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12914790 — Biomarker: CES2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CES2; ICE
Study 8588384 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 17680205 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16080808 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16080808 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11136842 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2542549 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2542549 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 16945045 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9246958 — Biomarker: IGFBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP1; IBP1
Study 17671280 — Biomarker: GRIK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIK4; GRIK
Study 17671280 — Biomarker: HTR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2A; HTR2
Study 24636340 — Biomarker: MMD mRNA
Type: Predictive Biomarker (PRD)
Genes: MMD; PAQR11
Study 24636340 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 11501455 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 2691478 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27684308 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 22263674 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22263674 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22263674 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22263674 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22166525 — Biomarker: GLI2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLI2; THP
Study 17635177 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1951336 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 28974849 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21955403 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21955403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8457237 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 8457237 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 31372210 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 10381531 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 7721419 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 7721419 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7721419 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 10145317 — Biomarker: TTL mRNA
Type: Predictive Biomarker (PRD)
Genes: TTL
Study 11985186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 776441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23731768 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21411606 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 19268410 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9477980 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16473984 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 10692524 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10692524 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9179687 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 1422972 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1422972 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 1422972 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 24607301 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24607301 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24607301 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24607301 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 22952756 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2514430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25472509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23750422 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23750422 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23750422 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19261138 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 30833435 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 14694036 — Biomarker: Neurofilament light polypeptide
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: NEFL; NF68; NFL
Study 14694036 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study 27232052 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 27232052 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 20189517 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 18180641 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6152739 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24383505 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27129892 — Biomarker: Succinate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: SDHD
Study 25330671 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18824643 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 18824643 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10597783 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8521562 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1958433 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 17325296 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17325296 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11788172 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7979426 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 26405092 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 26405092 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 26405092 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 23138388 — Biomarker: CNR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNR1; CNR
Study 17192538 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17192538 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22520119 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 17010979 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7639806 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12476475 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22122202 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12153608 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16799399 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 8355124 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 8355124 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31397179 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 27858072 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27858072 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23672570 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 14629771 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10735900 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30423575 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12516106 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 20129825 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10150537 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27315546 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20549829 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20549829 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 20549829 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 16155261 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 1334821 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30277921 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15983301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10877192 — Biomarker: OTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 6869204 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6869204 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22972862 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4