AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 18955454 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 16939990 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 8824106 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8824106 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18230792 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 8858403 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 1495520 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1495520 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22044855 — Biomarker: ACTG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACTG1; ACTG
Study 17005075 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17005075 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12725259 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7909642 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25775024 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 25775024 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 19376750 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24170101 — Biomarker: SOSTDC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOSTDC1; USAG1; CDA019
Study 24170101 — Biomarker: NFKB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NFKB2; LYT10
Study 24170101 — Biomarker: RELB mRNA
Type: Predictive Biomarker (PRD)
Genes: RELB
Study 16941276 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 28213783 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 28213783 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 28213783 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 25458745 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25458745 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25458745 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 30131099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25834495 — Biomarker: PTBP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTBP2; NPTB; PTB; PTBLP
Study 15677625 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12407637 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26715763 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 26715763 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17264781 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 7903217 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9252721 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16463811 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29052340 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18241749 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 6215056 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8751029 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29948216 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 7916183 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28343658 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 15333422 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9024246 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 3056447 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16856621 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8416660 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18295937 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18295937 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18295937 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 18295937 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18295937 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10814771 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 31888234 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31888234 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1369705 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15657588 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15657588 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9475316 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 2884858 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14554218 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27908164 — Biomarker: FBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBP1; FBP
Study 22403352 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10420094 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22286364 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 17377905 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 11593093 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30830672 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 19332211 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15764956 — Biomarker: PPOX
Type: Safety Biomarker (SAF)
Genes: HCRT; OX
Study 8704435 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 21537155 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21537155 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 16226163 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17299195 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8432669 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9060545 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9060545 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 3720755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29131079 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27759486 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25173606 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20837847 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 15078749 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10792152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25568079 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 25568079 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 15558528 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9381772 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26679695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20955582 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 7636894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2526172 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 31541606 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21807323 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3230152 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30782930 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30782930 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21128991 — Biomarker: PLXNA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 27909035 — Biomarker: CPTP mRNA
Type: Predictive Biomarker (PRD)
Genes: CPTP; GLTPD1
Study 15502720 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 20386063 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18316526 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 12439090 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6384072 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26700848 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 18018468 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7836703 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 29756523 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1105628 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 25465711 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 17378196 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 15126927 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29029193 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 17972380 — Biomarker: ARSB mRNA
Type: Predictive Biomarker (PRD)
Genes: ARSB
Study 16376756 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23866812 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 22856526 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 30206162 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 30206162 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 6818867 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30910544 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30910544 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 15793171 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26024521 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 23705968 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22278623 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9219699 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27464467 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 20463641 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 12660312 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8862490 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8862490 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1640854 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 1640854 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 22700685 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 10701814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9269703 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8443032 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8443032 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3535357 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28004200 — Biomarker: Zinc finger protein GLI1
Type: Predictive Biomarker (PRD)
Genes: GLI1; GLI
Study 1592277 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 1592277 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 30469412 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21313926 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 21313926 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 24955613 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 24955613 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24955613 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24955613 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19938965 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 19938965 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 17523342 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 31817936 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12665408 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10416459 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31924277 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29199100 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24395288 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20332588 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 7751881 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 26219161 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21812889 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21812889 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16449339 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11035889 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 8848410 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 8848410 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 8848410 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 6825123 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 26077241 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 16423633 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16423633 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16423633 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16423633 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16423633 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15265190 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 15265190 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15265190 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9524832 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23884387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18423869 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 8668059 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8668059 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 8668059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7395772 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 22244567 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 22244567 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 22244567 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 2140325 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 29895590 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23058854 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10726009 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 22765882 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29575386 — Biomarker: PTBP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTBP2; NPTB; PTB; PTBLP
Study 14562993 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22378291 — Biomarker: PPARG mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARG; NR1C3
Study 22378291 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 28238195 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15553604 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 9444446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19614943 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16861090 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16861090 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17651144 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 17651144 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 10424293 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 19302902 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8712383 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11039135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1655177 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 1655177 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22262484 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 22262484 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 22262484 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 17524265 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12077732 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 21439546 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 19436663 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19436663 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19436663 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19436663 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9806655 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 24768657 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12364460 — Biomarker: GHR mRNA
Type: Predictive Biomarker (PRD)
Genes: GHR
Study 18608103 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 647213 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 647213 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 29462095 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29462095 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24738516 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24738516 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18422205 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 29801123 — Biomarker: Complement factor D
Type: Safety Biomarker (SAF)
Genes: CFD; DF; PFD
Study 20013816 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1496965 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31215460 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27608437 — Biomarker: SV2A mRNA
Type: Predictive Biomarker (PRD)
Genes: SV2A; KIAA0736; PSEC0174
Study 16386522 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 16386522 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9930597 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24866022 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24866022 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 24866022 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 18064446 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 18064446 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16055569 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 12658791 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10512925 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 26669430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)