AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 19149760 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 15202617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25638740 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 25638740 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 25638740 — Biomarker: GDNF mRNA
Type: Predictive Biomarker (PRD)
Genes: GDNF
Study 19138934 — Biomarker: FHIT mRNA
Type: Predictive Biomarker (PRD)
Genes: FHIT
Study 1415419 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31917424 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23657091 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 23657091 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 23657091 — Biomarker: MAST1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAST1; KIAA0973; SAST
Study 23657091 — Biomarker: ACAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAT1; ACAT; MAT
Study 19708562 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 19708562 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8918276 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10378920 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25831651 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 16194048 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12022239 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30346226 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 27797925 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 27797925 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 27797925 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26110815 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 21294797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9138682 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29730458 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 24372884 — Biomarker: CELF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CELF4; BRUNOL4
Study 22289695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9433680 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 9433680 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 9433680 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 22075171 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 20088993 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 8888089 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3125575 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29525494 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27487342 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 20569506 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30514803 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 30514803 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 25418218 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15293053 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2913779 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2913779 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26350273 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 26350273 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 8455310 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8455310 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20194448 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1624634 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 29372470 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 19227901 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15895898 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12195121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11233145 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21820539 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17077730 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9661740 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 31694237 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31694237 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31694237 — Biomarker: AIP mRNA
Type: Predictive Biomarker (PRD)
Genes: AIP; XAP2
Study 31694237 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31694237 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31694237 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26057939 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23937271 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 21803422 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 19781210 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19781210 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 16487269 — Biomarker: GNB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNB3
Study 16487269 — Biomarker: GNB3
Type: Predictive Biomarker (PRD)
Study 29607480 — Biomarker: COL17A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL17A1; BP180; BPAG2
Study 29607480 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 23556337 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 23556337 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 23556337 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 23556337 — Biomarker: ABCG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 23556337 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 8498732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30289174 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 30289174 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 20420639 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 3814226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27022112 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27022112 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 25233931 — Biomarker: UGT2B10 mRNA
Type: Predictive Biomarker (PRD)
Genes: UGT2B10
Study 17885721 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 9094063 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19210135 — Biomarker: SYNE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SYNE2; KIAA1011; NUA
Study 15548759 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 9760346 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8091168 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 2968363 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 30013785 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 29233783 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 24202240 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 10633478 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 31950855 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11451210 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1071671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31121015 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21669162 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21669162 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 21669162 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1416161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10468701 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 10468701 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 2105070 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26858279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22843789 — Biomarker: FGD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGD4; FRABP; ZFYVE6
Study 22843789 — Biomarker: EPHA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPHA5; BSK; EHK1; HEK7; TYRO4
Study 17545373 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 16287454 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 12221405 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 31443727 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 19809205 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9211021 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31221679 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23328090 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12742982 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 10823263 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10823263 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8888744 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 23700932 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11876691 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 6383111 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23228988 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 9384464 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9384464 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 9384464 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 9384464 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9384464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1314337 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 29652778 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 25064627 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 29636004 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29636004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28543352 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 15705991 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 30032394 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 27294349 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 19081190 — Biomarker: GCH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCH1; DYT5; GCH
Study 15242361 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 31748427 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31748427 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 31748427 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31748427 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31748427 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 31748427 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20877300 — Biomarker: GDA mRNA
Type: Predictive Biomarker (PRD)
Genes: GDA; KIAA1258
Study 20877300 — Biomarker: KCNIP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNIP4; CALP; KCHIP4
Study 20877300 — Biomarker: APOO mRNA
Type: Predictive Biomarker (PRD)
Genes: APOO; FAM121B; MIC23; MIC26; My025; UNQ1866/PRO4302
Study 20877300 — Biomarker: NTRK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NTRK2; TRKB
Study 20877300 — Biomarker: GRIP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIP1
Study 20877300 — Biomarker: NXPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXPH1; NPH1; Nbla00697
Study 20877300 — Biomarker: ANK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANK3
Study 20877300 — Biomarker: NTRK
Type: Predictive Biomarker (PRD)
Study 22676205 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22676205 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22676205 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20464479 — Biomarker: TOP2A mRNA
Type: Predictive Biomarker (PRD)
Genes: TOP2A; TOP2
Study 15728210 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7956987 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21689371 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 12661789 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12661789 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 3888591 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 21885625 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 21885625 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 9476677 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 7945128 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24950745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19860553 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8706196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16032519 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25369488 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20958145 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 23782463 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18587620 — Biomarker: CPD mRNA
Type: Predictive Biomarker (PRD)
Genes: CPD
Study 11283917 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9276357 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 9276357 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 2885122 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 24742341 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20142823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20142823 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28006816 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 28006816 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 28006816 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 15990456 — Biomarker: IFNAR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNAR1; IFNAR
Study 6100880 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6100880 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31660693 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 24357473 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24357473 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20955336 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 18173340 — Biomarker: BAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAK1; BAK; BCL2L7; CDN1
Study 15985575 — Biomarker: GSS mRNA
Type: Predictive Biomarker (PRD)
Genes: GSS
Study 12486283 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12486283 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 10785284 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10785284 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 10785284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30531690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30531690 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9438780 — Biomarker: PLXNA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 29727545 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 24143017 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24143017 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17175376 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 7679737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26549803 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22326480 — Biomarker: ASPSCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 6093979 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 12958395 — Biomarker: TSN mRNA
Type: Predictive Biomarker (PRD)
Genes: TSN
Study 10945387 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 22355008 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 12805389 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12805389 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 11591618 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24595224 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28364270 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25887140 — Biomarker: NOD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOD2; CARD15; IBD1
Study 11716203 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 11716203 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 11716203 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 3307635 — Biomarker: TAOK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 18811802 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 14672354 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8603962 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31545671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26213242 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 20502695 — Biomarker: RND3 mRNA
Type: Predictive Biomarker (PRD)
Genes: RND3; ARHE; RHO8; RHOE
Study 20502695 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 20502695 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 8839230 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9888411 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 9888411 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 540461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31436371 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 1328367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26702863 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20511029 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 12821428 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 12821428 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 10227007 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29440218 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN