AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 21646616 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 21646616 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21646616 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19351734 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12875313 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8960814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14870956 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 27870567 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 27250730 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6211981 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 6211981 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2669553 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 31408377 — Biomarker: Osteopontin
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SPP1; BNSP; OPN; PSEC0156
Study 31408377 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 14558954 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 29377462 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22222208 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 7690082 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7690082 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 7690082 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 7690082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18512141 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29956827 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 26762838 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25384473 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17885551 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2189951 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30706508 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 17409404 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29759104 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 16084762 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 9636847 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21288144 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11165203 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3007605 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3007605 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30545333 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8091384 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9212965 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31752829 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 31752829 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21269547 — Biomarker: EPHA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPHA1; EPH; EPHT; EPHT1
Study 16952781 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 16952781 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 11149473 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11149473 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 3119786 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 6431573 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6431573 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30887937 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30887937 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30086659 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30086659 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 30086659 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22785573 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16979991 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8894145 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 25234206 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2874821 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29774642 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 26614823 — Biomarker: IGF2R mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF2R; MPRI
Study 12682480 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12682480 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12682480 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 12682480 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 12682480 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16873699 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16873699 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 16873699 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12623959 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10519687 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 23588557 — Biomarker: Lysosomal acid glucosylceramidase
Type: Pharmacodynamic Biomarker (PDY)
Genes: GBA1; GBA; GC; GLUC
Study 10809861 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 24858158 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 19848198 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19848198 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17854429 — Biomarker: TLR9
Type: Predictive Biomarker (PRD)
Genes: CD289
Study 27370396 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 21272325 — Biomarker: STC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STC1; STC
Study 21272325 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 19561152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8050452 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 8050452 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8050452 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 8050452 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8050452 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25847934 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 15611216 — Biomarker: Beta-secretase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: BACE1; BACE; KIAA1149
Study 8017464 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23936377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23936377 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23936377 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22044858 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22044858 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 16939848 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 9611062 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 15103312 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19585395 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 17762658 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 17762658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1895978 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9087160 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 3842544 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30706571 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 30706571 — Biomarker: TOMM40 mRNA
Type: Predictive Biomarker (PRD)
Genes: TOMM40; C19orf1; PEREC1; TOM40
Study 30706571 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 30706571 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 30706571 — Biomarker: SORL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SORL1; C11orf32
Study 24738835 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 19640359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2893778 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28387058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18230798 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 14684712 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31838405 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 30624371 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 24457276 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 7826904 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28641838 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 15961759 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 19371522 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 24275838 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24275838 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18280619 — Biomarker: EHF mRNA
Type: Predictive Biomarker (PRD)
Genes: EHF; ESE3; ESE3B; ESEJ
Study 15902987 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15902987 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 1691367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25455437 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23636153 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 10809268 — Biomarker: OPRM1
Type: Safety Biomarker (SAF)
Genes: MOR1; MOP
Study 1317343 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 29465549 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7846539 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 30580454 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 30580454 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 30580454 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30580454 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 30580454 — Biomarker: c-Jun N-terminal kinase
Type: Safety Biomarker (SAF)
Study 29083936 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 27538188 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 18391460 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 10546920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1711261 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 6406947 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29191561 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18670195 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 17451570 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9678528 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 9678528 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29554385 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17631083 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7852209 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 16292319 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9316956 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8398293 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 23419552 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 21366899 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19535243 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 17513798 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 11887802 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 11887802 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11887802 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11887802 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9512112 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 9512112 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9512112 — Biomarker: CXCL1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 9512112 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 16907931 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 16907931 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28541810 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24754265 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 20613498 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 19010201 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19010201 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 30248152 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15968293 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 223601 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 223601 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 30630567 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 11334202 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11334202 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 27871827 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 19727884 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15114551 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23569370 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 20331687 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 20331687 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 31949084 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 12411798 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12411798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31335865 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23759203 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 19945297 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 16823366 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16508259 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 29258678 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22872988 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22872988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6336719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3289645 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3289645 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26325387 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12477503 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 12477503 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10325282 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31133061 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 26341706 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 17088002 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15178687 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 8595925 — Biomarker: CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR1; C3BR
Study 8595925 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 365249 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31859246 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 31859246 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31859246 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31859246 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19001447 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16882745 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 15172401 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 9205920 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 2450244 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2450244 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25382325 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 19033608 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12052450 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9822138 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9822138 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23596814 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18930251 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 11728663 — Biomarker: PLN mRNA
Type: Predictive Biomarker (PRD)
Genes: PLN; PLB
Study 3666688 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 19332196 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19332196 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30587468 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26602699 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)