AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24933196 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18008221 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 7933707 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 2012295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16765700 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3222686 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26083696 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15575343 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15575343 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18832295 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 29979388 — Biomarker: CPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPB1; CPB; PCPB
Study 23646468 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23646468 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 15074089 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30446275 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30446275 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 29558756 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 29558756 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12030915 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 18580406 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 18580406 — Biomarker: ABCG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG1; ABC8; WHT1
Study 10805048 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9894580 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 9894580 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 24481688 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29476810 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 24742970 — Biomarker: Urinary total protein
Type: Safety Biomarker (SAF)
Study 21679006 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31432072 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22910291 — Biomarker: DYSF mRNA
Type: Predictive Biomarker (PRD)
Genes: DYSF; FER1L1
Study 11793169 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10833286 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 10833286 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 31146440 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 28103811 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 15526839 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15526839 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 15526839 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 20384968 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 18534364 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 16355614 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16355614 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11374327 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 3590300 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17009541 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 15297084 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 15297084 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9066384 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 25514459 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 25514459 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18469252 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11130522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11130522 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30507227 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 17890873 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11979067 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 11979067 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 23472458 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 17267326 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15310086 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15310086 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 2528841 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 756476 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 756476 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21450580 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 21450580 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18488201 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 12574201 — Biomarker: CASR mRNA
Type: Predictive Biomarker (PRD)
Genes: CASR; GPRC2A; PCAR1
Study 12574201 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6405607 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31651324 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19118301 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19498345 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30552275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26222203 — Biomarker: ABCA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA3; ABC3
Study 16026368 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31851799 — Biomarker: Homologous recombination deficiency
Type: Predictive Biomarker (PRD)
Study 28692122 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 26837842 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 26837842 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 22197578 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27840383 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 27840383 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20926967 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15289793 — Biomarker: SLCO1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 11410117 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11731182 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28462577 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28462577 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 17603048 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 17115902 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17115902 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 7417369 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 31226660 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 31226660 — Biomarker: GATA-type zinc finger protein 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ZGLP1; GLP1
Study 31226660 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 26859547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25305352 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 25305352 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 25305352 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17012110 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17012110 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10981170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22936658 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 12848631 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 8963958 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8963958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12601506 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10365576 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 8660081 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1826048 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 16029995 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16029995 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28807667 — Biomarker: THBS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: THBS1; TSP; TSP1
Study 28807667 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 28807667 — Biomarker: PLIN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLIN2; ADFP
Study 10938492 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10938492 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8737690 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 8737690 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 1559860 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29035099 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29035099 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 24509273 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 24509273 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19960343 — Biomarker: RAD51 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAD51; RAD51A; RECA
Study 7385085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28287024 — Biomarker: FNDC5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FNDC5; FRCP2
Study 22070180 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 22070180 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 31136582 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28230784 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28230784 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23667649 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17512355 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17512355 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15161680 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 15161680 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9495264 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 31791665 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 21045724 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11261828 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11261828 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30360969 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 30360969 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 30360969 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27544583 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 27544583 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27544583 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24374088 — Biomarker: SLC10A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC10A3; DXS253E; P3
Study 18571267 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8067226 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 30608613 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 16448970 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11709454 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 27482615 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27482615 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 401690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22010915 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10863856 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9197874 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3547757 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26409014 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 12921333 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29248433 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 22574741 — Biomarker: SLCO2B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 9313245 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 8365305 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 16120137 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 11564390 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11564390 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 26479510 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 10337859 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 10337859 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10337859 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22040521 — Biomarker: UGT2B7 mRNA
Type: Predictive Biomarker (PRD)
Genes: UGT2B7; UGTB2B9
Study 22040521 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 22040521 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 17449576 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 31136549 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11446878 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 365428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28029362 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 26157049 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11845604 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11767208 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11767208 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11767208 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 8117360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29999194 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23611095 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 2560555 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2560555 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 9743818 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 30910489 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 18422164 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11185633 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18633764 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18633764 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 18633764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11829851 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 31414632 — Biomarker: ST7 mRNA
Type: Predictive Biomarker (PRD)
Genes: ST7; FAM4A1; HELG; RAY1
Study 27137716 — Biomarker: NKTR mRNA
Type: Predictive Biomarker (PRD)
Genes: NKTR
Study 11060830 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 22337508 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 15934094 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 30630772 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 29214526 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29214526 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 9684781 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 24615085 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23545707 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 23545707 — Biomarker: RAPGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 21715124 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9790393 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8543750 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29676140 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29676140 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18250349 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29500585 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 17663610 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 16194202 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11807406 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 10725989 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 19631774 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 30027292 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 7933639 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7933639 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25872769 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 25387601 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 21292635 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 16155359 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30467742 — Biomarker: Bacterial beta-glucuronidase
Type: Safety Biomarker (SAF)
Genes: uidA; gurA; gusA; b1617; JW1609
Study 28820468 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24367864 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10751104 — Biomarker: Succinate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: SDHD
Study 9156531 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9156531 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 27923550 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 23998158 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 9881990 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29661156 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29661156 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29661156 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 13677579 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)