AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 22958175 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 15295694 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9831304 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 9831304 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 19709691 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12072586 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7985892 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2154407 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2154407 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28062085 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 24216113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19133058 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28716656 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26063503 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 26063503 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 23151750 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 23151750 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15360994 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8376688 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20363993 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 19005437 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31288740 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28077858 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19405039 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3513684 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30939096 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30422235 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30422235 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 26987626 — Biomarker: TLR2
Type: Predictive Biomarker (PRD)
Genes: TIL4; CD282
Study 26987626 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31122894 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26218727 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 23967286 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21844821 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19625744 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 11167431 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11229246 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23944632 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 20679528 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 20679528 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 8958019 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1547962 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 3873582 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 21490523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15010071 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15010071 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15010071 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 3068191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21632815 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 18823693 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 11079651 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 15638820 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 15638820 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7727181 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7727181 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15554350 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15554350 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15554350 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24858657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22344613 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 21403038 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21403038 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19135567 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 19135567 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14734128 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14734128 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14734128 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 11726454 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11726454 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 11726454 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7873465 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16526560 — Biomarker: SLC38A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 10644869 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8795443 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30359862 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 24360978 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24360978 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24360978 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 24360978 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 23786894 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21794791 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 19366845 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 18515308 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18515308 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 15871845 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 22926446 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 20435656 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 20435656 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20435656 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10898322 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 2115613 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 31060615 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14614004 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 10721197 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19180837 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1974513 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30478094 — Biomarker: Complete renal response
Type: Surrogate Endpoint (SUR)
Study 28759403 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 23771713 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 28319494 — Biomarker: SLBP mRNA
Type: Predictive Biomarker (PRD)
Genes: SLBP; HBP
Study 15364775 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 18442638 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15890685 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 15890685 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 8075028 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 8075028 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 2609991 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2609991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29524398 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 27625301 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17823597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15751670 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15751670 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15751670 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21124328 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19455340 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 20189754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18332472 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 20819525 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 17393238 — Biomarker: RNASE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RNASE2; EDN; RNS2
Study 17393238 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 15763644 — Biomarker: IGFBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP1; IBP1
Study 7629756 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 7629756 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 7629756 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 28708930 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19765430 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16751166 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 8096373 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12723461 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11730394 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9213324 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2455105 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2455105 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29549005 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 29549005 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28288974 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23160180 — Biomarker: FADS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS1; FADSD5
Study 23160180 — Biomarker: FADS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS2
Study 16290043 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15518675 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 9122733 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 25142196 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 7648374 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11319723 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31208472 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 31208472 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 31208472 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 31208472 — Biomarker: CD70 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD70; CD27L; CD27LG; TNFSF7
Study 18066962 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 15906077 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12581422 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30819457 — Biomarker: EBP mRNA
Type: Predictive Biomarker (PRD)
Genes: EBP
Study 26056021 — Biomarker: DKK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DKK1; UNQ492/PRO1008
Study 24495633 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12117084 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 30636632 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 27831502 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20943783 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 20943783 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20943783 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 19364963 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11231439 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7468987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7468987 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 26003169 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23218591 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9248985 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 4207965 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 26561784 — Biomarker: OPN1SW mRNA
Type: Predictive Biomarker (PRD)
Genes: OPN1SW; BCP
Study 20884344 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20884344 — Biomarker: KLRG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRG1; CLEC15A; MAFA; MAFAL
Study 20884344 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 20884344 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 20884344 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 20884344 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17582289 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 15364316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28279967 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21188654 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21188654 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 21188654 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15188805 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 7915733 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7915733 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 2917701 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2917701 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30142037 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 17498020 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7978187 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31409915 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31409915 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12828724 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 8291869 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 3034016 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3034016 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29790415 — Biomarker: SLC47A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC47A1; MATE1
Study 2309640 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16753975 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9286741 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2887190 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2887190 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16875724 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12954465 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 12954465 — Biomarker: MGAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MGAT1; GGNT1; GLCT1; GLYT1; MGAT
Study 15365570 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 11239541 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 7508194 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 7508194 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 7508194 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 19854114 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18435852 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17158431 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24887381 — Biomarker: NRM mRNA
Type: Predictive Biomarker (PRD)
Genes: NRM; NRM29; UNQ555/PRO1112
Study 22305998 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19806530 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 11884902 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 2195013 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2931232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2011075 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2011075 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25896330 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25896330 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9692778 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 28922340 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23454404 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 16339157 — Biomarker: SDC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SDC1; SDC
Study 26325557 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26325557 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22484413 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21527115 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18958842 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12663295 — Biomarker: FUT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FUT1; H; HSC
Study 8633815 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29554535 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28718233 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19549691 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16700815 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)