AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 27110697 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22795712 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 19064574 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19064574 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19064574 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 17073955 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 17073955 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29912623 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 29912623 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29912623 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29912623 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16647885 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 8625230 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 3158783 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 19169063 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8739813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2065042 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2065042 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26871534 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 22709750 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19351830 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 9534106 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25801408 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12095667 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27130929 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25769319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20587723 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20587723 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 20587723 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20587723 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18249205 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18249205 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30082749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22241639 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22241639 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20068379 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 17029274 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 17029274 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18849173 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15280527 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15280527 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7121809 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31796013 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 26932142 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 14699463 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11156542 — Biomarker: SLAMF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLAMF1; SLAM
Study 9683005 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 9683005 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22098700 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10996387 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10996387 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3709031 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24037900 — Biomarker: MITF mRNA
Type: Predictive Biomarker (PRD)
Genes: MITF; BHLHE32
Study 24037900 — Biomarker: POMC mRNA
Type: Predictive Biomarker (PRD)
Genes: POMC
Study 23276521 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 18467085 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 15983954 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10566571 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6978111 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 10997885 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 1586602 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 1586602 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 4028619 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 29587851 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9391249 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 9391249 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 12172398 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 12172398 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 12885750 — Biomarker: DDC mRNA
Type: Predictive Biomarker (PRD)
Genes: DDC; AADC
Study 12885750 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27123448 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 11002380 — Biomarker: TGFB1
Type: Safety Biomarker (SAF)
Genes: CED; TGFbeta
Study 16163639 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2527532 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23124126 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23124126 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19501822 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 656266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6356901 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31783766 — Biomarker: MYRF mRNA
Type: Predictive Biomarker (PRD)
Genes: MYRF; C11orf9; KIAA0954; MRF
Study 31783766 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 15533734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8127017 — Biomarker: RCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RCN1; RCN
Study 8127017 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 2573371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3279 — Biomarker: PLG mRNA
Type: Predictive Biomarker (PRD)
Genes: PLG
Study 17548542 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 19002265 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 19002265 — Biomarker: Ribonucleoside-diphosphate reductase large subunit
Type: Predictive Biomarker (PRD)
Genes: RRM1; RR1
Study 19002265 — Biomarker: RRM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RRM2; RR2
Study 14564329 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1629506 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1629506 — Biomarker: ARID3B mRNA
Type: Predictive Biomarker (PRD)
Genes: ARID3B; BDP; DRIL2
Study 30145941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26829011 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26829011 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 24327173 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 15753847 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 7904931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31647503 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31647503 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 16685055 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 16685055 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 16685055 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16685055 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23453459 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 23453459 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8160567 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 28272197 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 28272197 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23656493 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20163941 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 20163941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20163941 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17711689 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11723089 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11723089 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30032506 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25136078 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 19921102 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 15845094 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 15814220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8532944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29117618 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29117618 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 22290281 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22290281 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14570627 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 9875874 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25795462 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 25795462 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 25795462 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 25795462 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 25795462 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 11474324 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21638157 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12095157 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 12095157 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 12095157 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18330493 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8442968 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30796424 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 30796424 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 27319096 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27319096 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23770005 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22076253 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 22076253 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 12351470 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12351470 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7498100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30406883 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23847964 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17315307 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17315307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17315307 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 15014181 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28396565 — Biomarker: TRPM8 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPM8; LTRPC6; TRPP8
Study 17879411 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 15346355 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 1968784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23777507 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 23777507 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16320801 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12030110 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 25340384 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15485755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28481690 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8320424 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 28497534 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 28497534 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27557654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28704936 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 28704936 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28160288 — Biomarker: SLC7A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC7A5; CD98LC; LAT1; MPE16
Study 26700861 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11445758 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30639384 — Biomarker: HOXA9 mRNA
Type: Predictive Biomarker (PRD)
Genes: HOXA9; HOX1G
Study 25797560 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 11349178 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3526819 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22924949 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20668250 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 20668250 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20668250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7489529 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7489529 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27320173 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22898678 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 22898678 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 16401958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16401958 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12876177 — Biomarker: CARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARS1; CARS
Study 25548261 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 20014458 — Biomarker: STAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT1
Study 28141620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26107810 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 11475744 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 26571987 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 26571987 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26571987 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 26571987 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 15750254 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11281559 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7505423 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 3112002 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 24726046 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20479759 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 18349391 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2865857 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7756393 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 31939347 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28727165 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28727165 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21714686 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12719053 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25569324 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25569324 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25569324 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8693545 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 24439655 — Biomarker: NPSR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NPSR1; GPR154; GPRA; PGR14
Study 8477913 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 8477913 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3818024 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16014139 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31854293 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26825083 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20329606 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 10463682 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 30932958 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24314119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15612964 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 9435425 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9435425 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9435425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2568817 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 2568817 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 26449617 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 24106072 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 24106072 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 8931202 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17907290 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 10407505 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 10407505 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)