AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 15023669 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24119521 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 18781288 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 11728983 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3319147 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 23786174 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 6996627 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20414043 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22206630 — Biomarker: Platelet-derived growth factor B
Type: Pharmacodynamic Biomarker (PDY)
Genes: PDGFB; PDGF2; SIS
Study 12162469 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29998139 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19158209 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 15562929 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9338047 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9338047 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25974146 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 21374657 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17175307 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 31791288 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 17050869 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28251755 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 19661926 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27599663 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21311065 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 3355243 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28449657 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25646297 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30782680 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 8053615 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8053615 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24919692 — Biomarker: TRIM63 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 24919692 — Biomarker: FBXO32 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FBXO32
Study 10805507 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8848991 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8848991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25959877 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 25959877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21617554 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16543910 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16543910 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15017529 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15017529 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15017529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15017529 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30915573 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30915573 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30915573 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29533303 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 29533303 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22404114 — Biomarker: IL17RD mRNA
Type: Predictive Biomarker (PRD)
Genes: IL17RD; IL17RLM; SEF; UNQ6115/PRO20026
Study 7793821 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 7793821 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 2354386 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29477817 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 12085250 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 12085250 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31054484 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 26480546 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 26480546 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26480546 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 26480546 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 26480546 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 21747013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12898306 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10193418 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 10193418 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 10193418 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26329790 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 26329790 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 26329790 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 23484610 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19245300 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19245300 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 24487691 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22712469 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17823766 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22714699 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 22714699 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26070976 — Biomarker: PAG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAG1; CBP; PAG
Study 23722054 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23722054 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31521831 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 12162936 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7051913 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 7051913 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 31515716 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 24868024 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20015219 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 20015219 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 20015219 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12177267 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2112080 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 26475266 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26475266 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 29737805 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29737805 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29737805 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24429175 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16043735 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 26935044 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 26935044 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 22497849 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 17908974 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 31505665 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 19453313 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7519696 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23171610 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 23171610 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 20187899 — Biomarker: GLS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS2; GA
Study 2220651 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2220651 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2220651 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2220651 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27624505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12225701 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12225701 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9447863 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 8523623 — Biomarker: PPOX
Type: Safety Biomarker (SAF)
Genes: HCRT; OX
Study 31351492 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 21844879 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17484348 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15115251 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11135718 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 7881705 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2908300 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24360050 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24360050 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14656280 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10962520 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8783393 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 27066739 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12657097 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12657097 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 10723579 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 1541084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29534736 — Biomarker: REG3A mRNA
Type: Predictive Biomarker (PRD)
Genes: REG3A; HIP; PAP; PAP1
Study 26882043 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 26882043 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10604482 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10604482 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 20525836 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 12373046 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 12373046 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 12373046 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21525141 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 7988077 — Biomarker: TNFRSF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF21; DR6; UNQ437/PRO868
Study 8348277 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26496853 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 26496853 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 15914535 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8537688 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1907074 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 7051244 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28129130 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 9564459 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 26341595 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 23237679 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 11578014 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11578014 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9692113 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26126940 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 19558398 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 14595084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9196111 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 8311085 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31981567 — Biomarker: OSM mRNA
Type: Predictive Biomarker (PRD)
Genes: OSM
Study 31648099 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 31648099 — Biomarker: HRG mRNA
Type: Predictive Biomarker (PRD)
Genes: HRG
Study 28950289 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22796122 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22796122 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21185525 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9126665 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 29183782 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12887472 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 19507458 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17418019 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 12456630 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 12456630 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 1334126 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 1724541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23127169 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 2130823 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2130823 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 28648880 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 22474534 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16104901 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 19563641 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19563641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15241347 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 15241347 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 15241347 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8183178 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 27895466 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 27895466 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27895466 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12466334 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12466334 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12466334 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8991563 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 14503053 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 14503053 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11768164 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 21677054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26874076 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11407290 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9297265 — Biomarker: AHSP mRNA
Type: Predictive Biomarker (PRD)
Genes: AHSP; EDRF; ERAF
Study 8427863 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19276255 — Biomarker: CDKN1B mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN1B; KIP1; p27
Study 15080782 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 11306209 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9704773 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 9704773 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 16538619 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16538619 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22456295 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 22456295 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20089783 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 15853207 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 15853207 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 21360075 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11166898 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 1588830 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 12599843 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11236244 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29261010 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26892582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26892582 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26892582 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19370271 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 19370271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9199483 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 1362821 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30297199 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 16093465 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11840179 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 7214787 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 25801871 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25801871 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25801871 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18378520 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18378520 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11434703 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 11434703 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 11434703 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8311283 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27154871 — Biomarker: BMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BMP2; BMP2A
Study 27154871 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 27154871 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF