AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 29502530 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 29504262 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 29504262 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 29506157 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29506392 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 29506523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29506984 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29506984 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29506988 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29506988 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 29507077 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 29507099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29507732 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 29508095 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29509546 — Biomarker: PARP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PARP1; ADPRT; PPOL
Study 29510707 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29510707 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29510755 — Biomarker: AP5B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AP5B1; PP1030
Study 29510755 — Biomarker: RREB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RREB1; FINB
Study 29510755 — Biomarker: OBSCN mRNA
Type: Predictive Biomarker (PRD)
Genes: OBSCN; KIAA1556; KIAA1639
Study 29510755 — Biomarker: DNAH11 mRNA
Type: Predictive Biomarker (PRD)
Genes: DNAH11
Study 29510755 — Biomarker: IDO2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDO2; INDOL1
Study 29510755 — Biomarker: IGSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGSF3; EWI3; KIAA0466
Study 29510755 — Biomarker: KNL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KNL1; CASC5; KIAA1570
Study 29511132 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 29512061 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 29514256 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29514648 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 29514648 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 29514663 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 29514773 — Biomarker: DPT mRNA
Type: Predictive Biomarker (PRD)
Genes: DPT
Study 29514815 — Biomarker: S100A12 mRNA
Type: Predictive Biomarker (PRD)
Genes: S100A12
Study 29515114 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 29515114 — Biomarker: CALR mRNA
Type: Predictive Biomarker (PRD)
Genes: CALR; CRTC
Study 29515114 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study 29515114 — Biomarker: ASXL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASXL1; KIAA0978
Study 29517122 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29517122 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 29517122 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29518553 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 29519925 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 29522089 — Biomarker: HDGFL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: HDGFL2; HDGF2; HDGFRP2; HRP2; UNQ785/PRO1604
Study 29522186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29522361 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29523169 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 29523171 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 29524090 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29529007 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29529147 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 29530274 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29530667 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29530935 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29530989 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29531651 — Biomarker: SLAMF7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLAMF7; CS1; UNQ576/PRO1138
Study 29531651 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 29531784 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 29531837 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 29531837 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29531839 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29531839 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29532243 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29533369 — Biomarker: TACR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TACR3; NK3R; TAC3R
Study 29533458 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29533458 — Biomarker: EGFR
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ERBB1; ERRP
Study 29533755 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29534171 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 29534198 — Biomarker: MAX mRNA
Type: Predictive Biomarker (PRD)
Genes: MAX; BHLHD4
Study 29534721 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29535712 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 29535869 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 29536526 — Biomarker: Platelet count response
Type: Surrogate Endpoint (SUR)
Study 29538669 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 29540427 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29540575 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 29541969 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 29543932 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 29544445 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29544454 — Biomarker: S100A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: S100A4; CAPL; MTS1
Study 29544547 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 29544699 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 29545095 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29545095 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 29545283 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 29546316 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 29546316 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 29546316 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 29546316 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29548277 — Biomarker: KCNH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNH2; ERG; ERG1; HERG
Study 29548277 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 29548300 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29548934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29549159 — Biomarker: TNFRSF9 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF9; CD137; ILA
Study 29550316 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 29550382 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 29551338 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29551711 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 29551775 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 29551893 — Biomarker: SFRP5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SFRP5; FRP1B; SARP3
Study 29553382 — Biomarker: ATXN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATXN1; ATX1; SCA1
Study 29553382 — Biomarker: Ataxin-2
Type: Pharmacodynamic Biomarker (PDY)
Genes: ATXN2; ATX2; SCA2; TNRC13
Study 29553382 — Biomarker: Ataxin-3
Type: Pharmacodynamic Biomarker (PDY)
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 29553852 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29553852 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29554265 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 29555305 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 29556416 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29556418 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29556418 — Biomarker: CXCL13 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL13; BCA1; BLC; SCYB13
Study 29556418 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 29556418 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29556418 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 29556418 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 29556418 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29558274 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 29559561 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29559561 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 29559773 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 29560093 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29561066 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 29561296 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29561296 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29562855 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29563634 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29565424 — Biomarker: Lysosomal alpha-glucosidase
Type: Safety Biomarker (SAF)
Genes: GAA
Study 29565424 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29566106 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 29566186 — Biomarker: TLR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR1; KIAA0012
Study 29566186 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 29566186 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 29566186 — Biomarker: TLR10 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR10; UNQ315/PRO358
Study 29566186 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 29566186 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 29566186 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 29566186 — Biomarker: NFKB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NFKB1
Study 29566195 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 29566699 — Biomarker: PSMA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSMA4; HC9; PSC9
Study 29566699 — Biomarker: EGLN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EGLN2; EIT6
Study 29566699 — Biomarker: WNT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: WNT3; INT4
Study 29566699 — Biomarker: DCBLD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DCBLD1
Study 29566762 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29567071 — Biomarker: GZMB mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: GZMB; CGL1; CSPB; CTLA1; GRB
Study 29567071 — Biomarker: WARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WARS1; IFI53; WARS; WRS
Study 29567071 — Biomarker: SFRP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SFRP4; FRPHE
Study 29567071 — Biomarker: CDX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDX1
Study 29567632 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 29567632 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 29567632 — Biomarker: FOXO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXO1; FKHR; FOXO1A
Study 29567785 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 29567798 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 29568374 — Biomarker: Folate receptor alpha
Type: Predictive Biomarker (PRD)
Genes: FOLR1; FOLR
Study 29568762 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29570971 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 29570971 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 29570971 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 29570971 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 29570971 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 29570971 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 29571601 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29571946 — Biomarker: CSF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF1
Study 29571946 — Biomarker: CSF1R mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF1R; FMS
Study 29573889 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29573889 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29574070 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 29574070 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29575698 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 29578250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29579325 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 29579325 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 29579331 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29579370 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 29579597 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 29579607 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29580174 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 29581554 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29581554 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29584545 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 29587656 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29587677 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29587759 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 29587840 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29588304 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29590311 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 29590318 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29590318 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 29590318 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 29590335 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29590401 — Biomarker: ELK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELK3; NET; SAP2
Study 29590547 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 29590547 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 29590547 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 29593024 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29593099 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 29594435 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study 29594435 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 29594970 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29596029 — Biomarker: ROS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROS1; MCF3; ROS
Study 29596029 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 29596029 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 29599530 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 29601264 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29601264 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29601268 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29603015 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 29603764 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29604189 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29605405 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29605405 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29605813 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 29606415 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 29606415 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29606586 — Biomarker: Tropomyosin-related kinase A
Type: Pharmacodynamic Biomarker (PDY)
Genes: NTRK1; MTC; TRK; TRKA
Study 29606586 — Biomarker: NTRK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NTRK2; TRKB
Study 29606586 — Biomarker: NTRK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NTRK3; TRKC
Study 29607050 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 29608508 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 29608587 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 29608711 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29608809 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 29609013 — Biomarker: IL17F
Type: Predictive Biomarker (PRD)
Genes: IL-17F; ML-1; ML1
Study 29609532 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 29609532 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 29609536 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 29609555 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29609706 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 29609868 — Biomarker: GPX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPX1
Study 29609868 — Biomarker: SELENOP mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENOP; SELP; SEPP1
Study 29609868 — Biomarker: SELENOS mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENOS; SELS; VIMP; AD-015; SBBI8
Study 29609867 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 29610121 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 29610943 — Biomarker: ID1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ID1; BHLHB24; ID
Study 29611022 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 29611022 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1