AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 12842526 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1290620 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1290620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6742256 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30860001 — Biomarker: AMPH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMPH; AMPH1
Study 30860001 — Biomarker: CYBC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYBC1; C17orf62; EROS
Study 23251374 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19582491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2561144 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2561144 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26062187 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24135573 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 14706487 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 11990444 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 9650731 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 786135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31625262 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 23507424 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11737418 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11737418 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 11737418 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 11737418 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 7937352 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 31969108 — Biomarker: SLC12A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC12A3; NCC; TSC
Study 16441945 — Biomarker: GPX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPX1
Study 12829681 — Biomarker: ST8SIA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ST8SIA4; PST; PST1; SIAT8D
Study 29065098 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16222011 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2278366 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 2278366 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 25438821 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14531817 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 26498504 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16046372 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 12032191 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12032191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12032191 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 17684963 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15173493 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27046798 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 27046798 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17299062 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 8780347 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 18501444 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18501444 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15587771 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22430687 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 19398066 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 14586663 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28165762 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6378805 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22214253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9721772 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2512938 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 2512938 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31008902 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31008902 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31008902 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26185429 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26185429 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 15383190 — Biomarker: SRM mRNA
Type: Predictive Biomarker (PRD)
Genes: SRM; SPS1; SRML1
Study 11744907 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25330088 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23556437 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 8613041 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 17978603 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 17978603 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2691568 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23726159 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16205837 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 15458015 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 15458015 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 9084062 — Biomarker: PTK7 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTK7; CCK4
Study 26890230 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 24671049 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11907839 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 112944 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 112944 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 25881496 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 25881496 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9677793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22900583 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 22900583 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 21626525 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 23063703 — Biomarker: LHB mRNA
Type: Predictive Biomarker (PRD)
Genes: LHB
Study 27109630 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 14693987 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12401630 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8547549 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 28527129 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 12060966 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 12060966 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10085710 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10085710 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 7981011 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7981011 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14982510 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 9210004 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 29925421 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 29925421 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22508964 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 22508964 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 11455735 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31625118 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27753739 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7964515 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 7964515 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 7964515 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 25493952 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21617185 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 31064359 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26603745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16036495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 735294 — Biomarker: PRCP mRNA
Type: Predictive Biomarker (PRD)
Genes: PRCP; PCP
Study 31083176 — Biomarker: GRIK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIK4; GRIK
Study 31083176 — Biomarker: GRM7 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRM7; GPRC1G; MGLUR7
Study 31083176 — Biomarker: GRIA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIA1; GLUH1; GLUR1
Study 11376301 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11376301 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8685072 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 31618444 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27469482 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 18177441 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 16276071 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16276071 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 12975721 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12975721 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10731173 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20624243 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 12056293 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10692750 — Biomarker: PPEF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPEF1; PPEF; PPP7C
Study 30902674 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 30902674 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 30902674 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11498313 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16043683 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2529776 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21507295 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19934866 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 24586994 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24586994 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20404000 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12427413 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12427413 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26349919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18356605 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16206598 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16206598 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8527283 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 8527283 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24056905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19724055 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 9778202 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7759929 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2407872 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19794979 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31338807 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 21287288 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21287288 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11557835 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26632101 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10824625 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 8880558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27184989 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31177906 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 31177906 — Biomarker: EDNRA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDNRA; ETA; ETRA
Study 31177906 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21795455 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9506771 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7816418 — Biomarker: KCNH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNH2; ERG; ERG1; HERG
Study 30982223 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 30982223 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 30982223 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 23465178 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 19916992 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 14618095 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11009051 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 1395911 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 16046295 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 16046295 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 16046295 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16046295 — Biomarker: TNFA mRNA
Type: Predictive Biomarker (PRD)
Genes: TNF; TNFA; TNFSF2
Study 16046295 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30477800 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 30477800 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 30065941 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 30065941 — Biomarker: DMTN mRNA
Type: Predictive Biomarker (PRD)
Genes: DMTN; DMT; EPB49
Study 20203161 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 20203161 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 20203161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7546418 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 10942064 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 10942064 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 8843892 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8843892 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25104497 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7474322 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27012728 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27144828 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 24080653 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 23849964 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 21729881 — Biomarker: ZPR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZPR1; ZNF259
Study 21729881 — Biomarker: APOA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOA1
Study 21729881 — Biomarker: CYP4F2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP4F2
Study 21729881 — Biomarker: SCARB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SCARB1; CD36L1; CLA1
Study 16448524 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16448524 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22575312 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 12064916 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 9793811 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 7543785 — Biomarker: FMOD mRNA
Type: Predictive Biomarker (PRD)
Genes: FMOD; FM; SLRR2E
Study 825895 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 28691141 — Biomarker: NFKBIA
Type: Predictive Biomarker (PRD)
Genes: IKBA; MAD-3; IkappaBalpha
Study 28925529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25504269 — Biomarker: SHD mRNA
Type: Predictive Biomarker (PRD)
Genes: SHD
Study 24756903 — Biomarker: IL33 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL33; C9orf26; IL1F11; NFHEV
Study 24756903 — Biomarker: STAT5A mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT5A; STAT5
Study 16226164 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16226164 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7576400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8144852 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 3018023 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31774626 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 30683494 — Biomarker: AIP mRNA
Type: Predictive Biomarker (PRD)
Genes: AIP; XAP2
Study 26181174 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24290869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14737055 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8032072 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29482256 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 24770624 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 18940711 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30290680 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22071709 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 11131930 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8937934 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3479329 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 1426317 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 29193576 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24999076 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22859825 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20392870 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 20392870 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18514933 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18514933 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18514933 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 16200819 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 389839 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR