AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 17201073 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9342580 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 9342580 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27217455 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 30388905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28506387 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28506387 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25559011 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 25559011 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16144822 — Biomarker: RETN mRNA
Type: Predictive Biomarker (PRD)
Genes: RETN; FIZZ3; HXCP1; RSTN; UNQ407/PRO1199
Study 16144822 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 21787450 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 19488608 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15165944 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 23801867 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21795442 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 18198636 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18198636 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18198636 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7552649 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 28002685 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 20634639 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20634639 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7705677 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16432463 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 16596054 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1442643 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31751012 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29576358 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study 24918372 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17689171 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 3314458 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30697986 — Biomarker: Th2 cell
Type: Safety Biomarker (SAF)
Study 20368068 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15807187 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 15807187 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 15807187 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 30337921 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 21806617 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16388329 — Biomarker: HFE mRNA
Type: Predictive Biomarker (PRD)
Genes: HFE; HLAH
Study 12032877 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22827167 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22827167 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 17645387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11689736 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30076156 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22905971 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19634510 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 22174811 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 22174811 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17334239 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11795352 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 1928811 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27305192 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23288176 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 20234158 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 19284086 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19284086 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15818697 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15818697 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31655890 — Biomarker: CLCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLCN1; CLC1
Study 19923377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19923377 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15871014 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 4010979 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 4010979 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16194199 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 31594077 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 26427105 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 22256738 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22256738 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 16890673 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3476732 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 22592092 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 12756407 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29730659 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 20854630 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15057672 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11434650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11434650 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31652688 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17213752 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7923645 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 2468874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30883517 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 30883517 — Biomarker: CD8A mRNA
Type: Predictive Biomarker (PRD)
Genes: CD8A; MAL
Study 30883517 — Biomarker: NCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NCR1; LY94
Study 30883517 — Biomarker: TNFRSF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF4; TXGP1L
Study 30883517 — Biomarker: TNFRSF9 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF9; CD137; ILA
Study 28258520 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 28258520 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 28258520 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 28258520 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28258520 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 11052960 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3936739 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25986427 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 25986427 — Biomarker: OMG mRNA
Type: Predictive Biomarker (PRD)
Genes: OMG; OMGP
Study 25986427 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 25986427 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15963202 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11207870 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28121706 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28121706 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26780276 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28057652 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 25174865 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 18360014 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26912438 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17075991 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11342470 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9412887 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 3436104 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25341548 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24347531 — Biomarker: HPN mRNA
Type: Predictive Biomarker (PRD)
Genes: HPN; TMPRSS1
Study 21905270 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19064988 — Biomarker: ESR1
Type: Predictive Biomarker (PRD)
Genes: NR3A1; Era; ER-alpha
Study 19064988 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 19064988 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19064988 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 12123209 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 12123209 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 7778534 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17319827 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 10710012 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11322246 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6138058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17237316 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8990684 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 1424620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20530107 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 17090953 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17090953 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9395805 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 7957520 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31230088 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 28554939 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17018656 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11166015 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30919997 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22980301 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 15802780 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2407875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3146197 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 23604333 — Biomarker: CHRNA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA3; NACHRA3
Study 14668275 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 14668275 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 31456498 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 21934055 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 26178508 — Biomarker: Coagulation factor Va
Type: Safety Biomarker (SAF)
Genes: F5
Study 26178508 — Biomarker: F7 mRNA
Type: Predictive Biomarker (PRD)
Genes: F7
Study 26178508 — Biomarker: F9 mRNA
Type: Predictive Biomarker (PRD)
Genes: F9
Study 22669334 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15587828 — Biomarker: PGR mRNA
Type: Predictive Biomarker (PRD)
Genes: PGR; NR3C3
Study 2955804 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28736944 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26247037 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 2090557 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 28856940 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9212969 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 9212969 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 9212969 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 2447432 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29952503 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20555294 — Biomarker: STK39 mRNA
Type: Predictive Biomarker (PRD)
Genes: STK39; SPAK
Study 15932522 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12874489 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29052245 — Biomarker: FAIM mRNA
Type: Predictive Biomarker (PRD)
Genes: FAIM; FAIM1
Study 22882843 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22882843 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20156339 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 20156339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8556396 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29483383 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 29483383 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20837887 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16135590 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28017524 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 28017524 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 26780394 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26780394 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 26780394 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26780394 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23171573 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23171573 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30660136 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 30660136 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30660136 — Biomarker: LIF mRNA
Type: Predictive Biomarker (PRD)
Genes: LIF; HILDA
Study 30660136 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 22444781 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 22444781 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26834282 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20811299 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20811299 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 20811299 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2276936 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11454528 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11454528 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 9875837 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 3293399 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29482720 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 26358841 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26358841 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26358841 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24751388 — Biomarker: PRCP mRNA
Type: Predictive Biomarker (PRD)
Genes: PRCP; PCP
Study 11465644 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30736873 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19361589 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19361589 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16626943 — Biomarker: USH1G mRNA
Type: Predictive Biomarker (PRD)
Genes: USH1G; SANS
Study 11461714 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 28251260 — Biomarker: MAVS mRNA
Type: Predictive Biomarker (PRD)
Genes: MAVS; IPS1; KIAA1271; VISA
Study 12671332 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12671332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8857906 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30360498 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26892312 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22412842 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 22412842 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19281600 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 22169414 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19494028 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16340945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31592887 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25993609 — Biomarker: CFL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CFL1; CFL
Study 16226864 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12634979 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 12634979 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27553419 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22911473 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 11862365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24736085 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 22332206 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17975233 — Biomarker: BCL2A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCL2A1; BCL2L5; BFL1; GRS; HBPA1
Study 15772061 — Biomarker: ENTPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ENTPD1; CD39