AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 30255760 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30255760 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16109319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7739944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1675042 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31363328 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 23562192 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 19351943 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 15319494 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9406807 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 25406227 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 19000095 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 19000095 — Biomarker: SSB mRNA
Type: Predictive Biomarker (PRD)
Genes: SSB
Study 10510144 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6790048 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26084792 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26084792 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22194326 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 2285628 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31996940 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28135841 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28135841 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28135841 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8554003 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1886589 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 1886589 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15264735 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31391223 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 27708251 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 27708251 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 27708251 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27708251 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21536983 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11590875 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9125088 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 2979237 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 29878856 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 18356180 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 18356180 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18356180 — Biomarker: DKK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DKK1; UNQ492/PRO1008
Study 9504729 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9504729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26444473 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12665164 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 22955513 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2202231 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7040496 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7040496 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 15467498 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7534847 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31754703 — Biomarker: SLCO3A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO3A1; OATP3A1; OATPD; SLC21A11
Study 31754703 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 31754703 — Biomarker: NR1I2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1I2; PXR
Study 31754703 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 31754703 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 31754703 — Biomarker: MRP2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ABCC2; DJS; cMRP
Study 31754703 — Biomarker: ABCG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 19861543 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 16518959 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11506518 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11506518 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9407455 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19110359 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 19110359 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11585352 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10447226 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10447226 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10447226 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29725824 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25123295 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22376210 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 17495015 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 2478330 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 11171896 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 29970404 — Biomarker: VIM mRNA
Type: Predictive Biomarker (PRD)
Genes: VIM
Study 24618231 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18192950 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11669169 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24951103 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 19117833 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19117833 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17674917 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 14724665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8314960 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 28703491 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 28703491 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20184578 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12864879 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2945783 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29415668 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29415668 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 19671203 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7925877 — Biomarker: DDR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 7925877 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 31166599 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31166599 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23256446 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23256446 — Biomarker: PRCP mRNA
Type: Predictive Biomarker (PRD)
Genes: PRCP; PCP
Study 23256446 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 23256446 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18316155 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 18316155 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9783766 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2455840 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25514106 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23466048 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8238221 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8238221 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11563407 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1920340 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1920340 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31792485 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31792485 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31792485 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 31792485 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24965797 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 28407662 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8279841 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 27437883 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 24925464 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 1514169 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 15830180 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 24379010 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 21564156 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 2851762 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 30428290 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9105568 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 31977921 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 27262419 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27262419 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2110199 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 22571226 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 17473196 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 18848786 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 18786729 — Biomarker: CDS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDS1; CDS
Study 15800138 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 31982039 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 31982039 — Biomarker: JAK2
Type: Predictive Biomarker (PRD)
Genes: JTK10
Study 23150980 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17942609 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12858441 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1859518 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31504594 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 24332218 — Biomarker: PTGDR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 15711245 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2523548 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1071693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16960176 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 15055228 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 25471305 — Biomarker: LEPROT mRNA
Type: Predictive Biomarker (PRD)
Genes: LEPROT; LEPR; OBR
Study 25471305 — Biomarker: SIRPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIRPB1
Study 25471305 — Biomarker: Amphiregulin
Type: Safety Biomarker (SAF)
Genes: AREG; AREGB; SDGF
Study 25471305 — Biomarker: TNFAIP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFAIP3; OTUD7C
Study 10555884 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10555884 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10555884 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 10555884 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 1974748 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1974748 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31785551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25058107 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17356969 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30691766 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 28408697 — Biomarker: CX3CL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CX3CL1; FKN; NTT; SCYD1; A-152E5.2
Study 28408697 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18422779 — Biomarker: CLC mRNA
Type: Predictive Biomarker (PRD)
Genes: CLC; LGALS10; LGALS10A
Study 16195134 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22915637 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 22915637 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 18444532 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10999062 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10999062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22149452 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 22149452 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 31179485 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 28197938 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28197938 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29231407 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22459966 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 30569673 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26538525 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20163368 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 10793877 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29687898 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 28343401 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 9443096 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 31615291 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11293552 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11293552 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11293552 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27539149 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 26288392 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23220158 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10718389 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1680813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18357917 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 18357917 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 18357917 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 30664702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20308663 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9084524 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9084524 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 9084524 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9648963 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 2478779 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28625637 — Biomarker: CHEK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHEK1; CHK1
Study 25924819 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 23949918 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 18650507 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 18650507 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 8790926 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8790926 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1729864 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29974521 — Biomarker: Hypoxia-inducible factor 1-alpha
Type: Predictive Biomarker (PRD)
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 20198491 — Biomarker: GK mRNA
Type: Predictive Biomarker (PRD)
Genes: GK
Study 10696854 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 15753414 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29737412 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24333554 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 24333554 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23091128 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19114683 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 30545409 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 26791805 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 24257810 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 28170391 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 21616170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25830947 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 25830947 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12953851 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12953851 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27007919 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 27007919 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 9305340 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 11191542 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 31044227 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30180755 — Biomarker: SLPI mRNA
Type: Predictive Biomarker (PRD)
Genes: SLPI; WAP4; WFDC4
Study 22040465 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 16045524 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16045524 — Biomarker: PIBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PIBF1; C13orf24; PIBF