AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 8557059 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 31158840 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21415814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15351581 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 20357174 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19337553 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11029334 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 3914839 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12137243 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9740934 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 2220622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10583422 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 10583422 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1678273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17919140 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16485515 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10534683 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 10534683 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31126557 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31126557 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24998653 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24998653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22402864 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 2402210 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 25040039 — Biomarker: INPP5D mRNA
Type: Predictive Biomarker (PRD)
Genes: INPP5D; SHIP; SHIP1
Study 25040039 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 30844623 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25319731 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30595526 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 27422891 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23169286 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 18042508 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7540397 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 15167288 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29626465 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 8195908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27146272 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18440179 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 15170391 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28472693 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 17407626 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12519409 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12519409 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 31537559 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 25349227 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23138396 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23138396 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21636073 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16311275 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 10786260 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25721305 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29071331 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 24895566 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 8730557 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 29381666 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16043847 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 12417271 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 1776335 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 27998015 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 17765963 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17765963 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30719450 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27641367 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 21865574 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 11843249 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 25343235 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15145629 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15145629 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8445423 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25711324 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23902955 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28637773 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28637773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16630748 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14600520 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6410971 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 27329400 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 26194932 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 11061655 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2877759 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 2877759 — Biomarker: GCSAM mRNA
Type: Predictive Biomarker (PRD)
Genes: GCSAM; GAL; GCET2
Study 18937894 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12811613 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 31356921 — Biomarker: SYK mRNA
Type: Predictive Biomarker (PRD)
Genes: SYK
Study 31356921 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 31356921 — Biomarker: Interleukin 4 receptor alpha
Type: Predictive Biomarker (PRD)
Genes: IL4R; IL4RA; 582J2.1
Study 31356921 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 31356921 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC
Study 31356921 — Biomarker: CCL18 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 31356921 — Biomarker: CCL22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 31356921 — Biomarker: CCL26 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL26; SCYA26; UNQ216/PRO242
Study 31356921 — Biomarker: PI3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PI3; WAP3; WFDC14
Study 31356921 — Biomarker: CCL20 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL20; LARC; MIP3A; SCYA20
Study 29301124 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 11219162 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30366505 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 29366667 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 11292931 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 22230963 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 20378080 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31238161 — Biomarker: LRBA mRNA
Type: Predictive Biomarker (PRD)
Genes: LRBA; BGL; CDC4L; LBA
Study 17560664 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 9855155 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9855155 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21527660 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21527660 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8981141 — Biomarker: PALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PALM; KIAA0270
Study 27799756 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 11956267 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11956267 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study 11956267 — Biomarker: HLA-C
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HLA-JY3, D6S204, PSORS1
Study 28778185 — Biomarker: MYCN mRNA
Type: Predictive Biomarker (PRD)
Genes: MYCN; BHLHE37; NMYC
Study 16679259 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 15151263 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15151263 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 29550238 — Biomarker: CENPJ mRNA
Type: Predictive Biomarker (PRD)
Genes: CENPJ; CPAP; LAP; LIP1
Study 27425415 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 27425415 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 24032554 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 11894976 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 9592984 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1514709 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 31968102 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 31968102 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31968102 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30002437 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30002437 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 30159738 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 22834767 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22834767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21270359 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8827134 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1418778 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26466321 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 630965 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 30739259 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17925335 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 17925335 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17925335 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16669955 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 10745280 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10745280 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31021023 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31021023 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31021023 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 28841431 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16139717 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10540009 — Biomarker: OPRM1
Type: Safety Biomarker (SAF)
Genes: MOR1; MOP
Study 10540009 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 7599728 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31337342 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 16396865 — Biomarker: DCC mRNA
Type: Predictive Biomarker (PRD)
Genes: DCC; IGDCC1
Study 27441478 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 21630255 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 9734735 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 8295285 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8295285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30673020 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28431534 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28431534 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28431534 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28431534 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21701422 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 26983396 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 22614152 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20375709 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17656620 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 11824859 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 11824859 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 24154560 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 20151251 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 17684044 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 10219064 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25559818 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 25559818 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 25559818 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31027423 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2729124 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26025699 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20038724 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20038724 — Biomarker: TOP2A mRNA
Type: Predictive Biomarker (PRD)
Genes: TOP2A; TOP2
Study 20038724 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 27129358 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12006958 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7532192 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1646613 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26404365 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17768459 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10506849 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 2337209 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19761716 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 19761716 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 19761716 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 26313124 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 22926006 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22926006 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10678268 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10678268 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17545533 — Biomarker: ABCG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 8562960 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1992393 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30024999 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 17346705 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 7760093 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23380426 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 19713172 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12369047 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 31256724 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15618549 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 15618549 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 29775547 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29775547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21843930 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12386641 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12386641 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23855973 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23855973 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 8922766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17223409 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17223409 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7977316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26070913 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 23933953 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3554564 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24323178 — Biomarker: ESD mRNA
Type: Predictive Biomarker (PRD)
Genes: ESD
Study 20054187 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20054187 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20054187 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 20054187 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20054187 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 8704116 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31919123 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 29078971 — Biomarker: CD82 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD82; KAI1; SAR2; ST6; TSPAN27
Study 29078971 — Biomarker: ST7 mRNA
Type: Predictive Biomarker (PRD)
Genes: ST7; FAM4A1; HELG; RAY1
Study 26160548 — Biomarker: AMY1A mRNA
Type: Predictive Biomarker (PRD)
Genes: AMY1A; AMY1
Study 22325080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19672115 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 634895 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 31670238 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 31719124 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 28111430 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 21270194 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18377903 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25691677 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA