AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31947529 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 21525158 — Biomarker: GCKR mRNA
Type: Predictive Biomarker (PRD)
Genes: GCKR
Study 21525158 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19038501 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9525985 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 8306218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2917588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31416698 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28884566 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 23154587 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16681772 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 16681772 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 16681772 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 16681772 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 22382876 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 22382876 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20646560 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 11372590 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 31161726 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 25935877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24283598 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19194214 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 31071734 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 25465932 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 25465932 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 25465932 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16799819 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22738442 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2054279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25311554 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22931259 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 20673857 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 18173917 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15468166 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 15468166 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 20943753 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 11554430 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 1375019 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 25297058 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17440522 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16837436 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 16837436 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19347726 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study 10626094 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23368423 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23368423 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20417488 — Biomarker: Interleukin 4 receptor alpha
Type: Predictive Biomarker (PRD)
Genes: IL4R; IL4RA; 582J2.1
Study 20417488 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17220608 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 27522312 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24477514 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22710563 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20695899 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1409461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1409461 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1409461 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 4010387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31298269 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26052866 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31627998 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31627998 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28808144 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21571150 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12727970 — Biomarker: ALDH1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH1A2; RALDH2
Study 12727970 — Biomarker: CYP26A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP26A1; CYP26; P450RAI1
Study 12727970 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 11429666 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9134634 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15498183 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15498183 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 8131544 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 817373 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 15179339 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 8968295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15811482 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11821456 — Biomarker: HDC mRNA
Type: Predictive Biomarker (PRD)
Genes: HDC
Study 11821456 — Biomarker: SDC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SDC1; SDC
Study 8828946 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24037036 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 15163108 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 26540369 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24742658 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20496736 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 1449335 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21729789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15327583 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3005384 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3005384 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16461202 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7956751 — Biomarker: TRIM32 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM32; HT2A
Study 2455104 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7982295 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30640206 — Biomarker: FADS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS1; FADSD5
Study 16968570 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 11291826 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 2872805 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9459535 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 2671517 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19197823 — Biomarker: GSS mRNA
Type: Predictive Biomarker (PRD)
Genes: GSS
Study 16478902 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10755315 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8891856 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17931461 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 15826726 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 7710954 — Biomarker: MALT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MALT1; MLT
Study 26444986 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 19695030 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9627292 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27697703 — Biomarker: RNASE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RNASE2; EDN; RNS2
Study 7461567 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 20391324 — Biomarker: MXD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MXD1; MAD
Study 18992248 — Biomarker: Solute carrier family 29 member 1
Type: Predictive Biomarker (PRD)
Genes: SLC29A1; ENT1
Study 14984497 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 14984497 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9507791 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 9507791 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3370986 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 16501249 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 16501249 — Biomarker: BLM mRNA
Type: Predictive Biomarker (PRD)
Genes: BLM; RECQ2; RECQL3
Study 16501249 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 14665655 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27032570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12575551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28068681 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28068681 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11316648 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8076711 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 27707817 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 20378841 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18691293 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC
Study 18691293 — Biomarker: CCR3 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CCR3; CMKBR3
Study 18691293 — Biomarker: CCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR4; CMKBR4
Study 11273876 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 27776679 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 15703163 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11174795 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 799559 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31119578 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31119578 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11587253 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8162479 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 27916783 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19500693 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11451173 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31404750 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31404750 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 26302885 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 26302885 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26302885 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 26480544 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26480544 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14752676 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 3916444 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25524052 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23028596 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 15000754 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 10073836 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2071085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31504709 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25025992 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25025992 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21111985 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11674982 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29035394 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 1356175 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3893195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26771294 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9685104 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 9685104 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 799560 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23885658 — Biomarker: SLPI mRNA
Type: Predictive Biomarker (PRD)
Genes: SLPI; WAP4; WFDC4
Study 23885658 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 23885658 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 16392437 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12351451 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8775856 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 2148223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23448396 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 23448396 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 20965292 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 21577028 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15361775 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9313673 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 18480687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31232139 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31232139 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31232139 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31232139 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31232139 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26929396 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18981033 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 9295821 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31764785 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25398453 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25398453 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 25398453 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 25398453 — Biomarker: ERBB4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB4; HER4
Study 25398453 — Biomarker: Epiregulin
Type: Safety Biomarker (SAF)
Genes: EREG
Study 21985749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18270369 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11164441 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27357093 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27357093 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22435370 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 22435370 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9389813 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 27302208 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27302208 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 22381643 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19515415 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 19515415 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 17475412 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 1692944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31471421 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 11524048 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 11524048 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15931654 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 12851616 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1678372 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17418297 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 16720149 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1524757 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26542467 — Biomarker: CFI mRNA
Type: Predictive Biomarker (PRD)
Genes: CFI; IF
Study 23636235 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10948356 — Biomarker: TAOK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 4014120 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30921552 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 30921552 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28858387 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28858387 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20925938 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 21635243 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 24418359 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 10895027 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8826608 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26053726 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 26053726 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 17373905 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 17373905 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 17373905 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23804385 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 21633800 — Biomarker: Mitochondrial frataxin
Type: Monitoring Biomarker (MOI)
Genes: FXN; FRDA; X25
Study 9576635 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 7889886 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)