AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 1486738 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8273728 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9236672 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28111123 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18216286 — Biomarker: Dermal blood flow
Type: Pharmacodynamic Biomarker (PDY)
Study 26030111 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28759347 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 21270442 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 19581801 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 17132720 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 17132720 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15529604 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23677131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19302259 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 19302259 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19302259 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19302259 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 19302259 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 17507344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9271287 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15048662 — Biomarker: HTR2C mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2C; HTR1C
Study 9566644 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 9566644 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 2457767 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 28419890 — Biomarker: CTSA mRNA
Type: Predictive Biomarker (PRD)
Genes: CTSA; PPGB
Study 18341680 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26092649 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27935977 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22606978 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 20091824 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 10523008 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 10523008 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1773906 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21162796 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 14996521 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10434216 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 10434216 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10434216 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7822519 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 30905721 — Biomarker: GDNF mRNA
Type: Predictive Biomarker (PRD)
Genes: GDNF
Study 30905721 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25312997 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 21278620 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 21278620 — Biomarker: ALDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH2; ALDM
Study 21278620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20141097 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 31976576 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20003316 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20003316 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17314918 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 30770424 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 22041889 — Biomarker: GNB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNB3
Study 7957504 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 31335759 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24517057 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16704296 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 16704296 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 11523315 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11523315 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8539545 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 25033263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15636426 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 11791121 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 7953984 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22586212 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 22586212 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15947713 — Biomarker: LTB mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB; TNFC; TNFSF3
Study 15947713 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 1691406 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28676443 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30089732 — Biomarker: UCP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP1; SLC25A7; UCP
Study 30089732 — Biomarker: TMEM26 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMEM26
Study 30089732 — Biomarker: CIDEA mRNA
Type: Predictive Biomarker (PRD)
Genes: CIDEA
Study 27282232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15784718 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7955757 — Biomarker: CEACAM6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CEACAM6; NCA
Study 23239151 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21605022 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9663369 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9663369 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31735328 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30624150 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19691566 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12764909 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12764909 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11421893 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study 7506322 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7506322 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 7506322 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 336257 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20220747 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 20220747 — Biomarker: MRP2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ABCC2; DJS; cMRP
Study 20220747 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 20220747 — Biomarker: SLCO1B3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 20467528 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15646732 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 15646732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9510396 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 31922998 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28329211 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 21209231 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 9634262 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9634262 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1968233 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19167712 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19167712 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15502038 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 11522179 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7945560 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 29813097 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27578110 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 25703424 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25703424 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20384434 — Biomarker: IGF2BP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF2BP2; IMP2; VICKZ2
Study 20384434 — Biomarker: ADIPOQ mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 30069604 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23489301 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 9595286 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9595286 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9595286 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7801667 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3514833 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 3514833 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 25762401 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25762401 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 25762401 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19798074 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19798074 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18634501 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 10559092 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 30008589 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 8617079 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 12161494 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12161494 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 12161494 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17217362 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15961699 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 2523264 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31690775 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 31690775 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24824014 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18395165 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9583927 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30256277 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30256277 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30256277 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 30256277 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 30256277 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 15713907 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 1874208 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16129973 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29092881 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 28306389 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 28306389 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22965965 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22965965 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15194675 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 8483096 — Biomarker: FGG mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGG; PRO2061
Study 16027343 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 27040362 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20077495 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17611706 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15860392 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15860392 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7851363 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 31812328 — Biomarker: EMSY mRNA
Type: Predictive Biomarker (PRD)
Genes: EMSY; C11orf30; GL002
Study 31812328 — Biomarker: LRRC32 mRNA
Type: Predictive Biomarker (PRD)
Genes: LRRC32; D11S833E
Study 23842710 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 20110024 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1580283 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1580283 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1580283 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27615041 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9454908 — Biomarker: Proliferation marker protein Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67
Study 1710743 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1710743 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 8147328 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8147328 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31045229 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 28555011 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20089776 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 18054638 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 16076991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12242580 — Biomarker: FXYD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FXYD1; PLM
Study 30770586 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23714773 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 2948929 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15708698 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8933493 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8933493 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 8933493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27032639 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27032639 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27032639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7702795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3667138 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25499939 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25499939 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18007158 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12358134 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7488277 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 7034472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11908559 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 30779597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12450893 — Biomarker: Plasma sitosterol and campesterol
Type: Surrogate Endpoint (SUR)
Study 7670096 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20953684 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20953684 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20953684 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12110340 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 8737889 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 3904334 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29663044 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 26469139 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26469139 — Biomarker: STIL mRNA
Type: Predictive Biomarker (PRD)
Genes: STIL; SIL
Study 12797485 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8803515 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8803515 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8803515 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31944806 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 23815533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17359512 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17359512 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12514902 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2647187 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7894226 — Biomarker: SSB mRNA
Type: Predictive Biomarker (PRD)
Genes: SSB
Study 31863284 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 30653533 — Biomarker: FMR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMR1
Study 28228114 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 2083193 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30714233 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30714233 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26003637 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 15515782 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15515782 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30142760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16491216 — Biomarker: Hydroxyphenylpyruvate dioxygenase
Type: Safety Biomarker (SAF)
Genes: HPD; PPD
Study 12854150 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 2005316 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7022275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28886024 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 21345662 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17363767 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 17363767 — Biomarker: EPHX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPHX1; EPHX; EPOX
Study 17363767 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 25635977 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18667327 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18667327 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18667327 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 18667327 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8