AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 19635898 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16943671 — Biomarker: ADAM17 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM17; CSVP; TACE
Study 10170460 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30266270 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28470492 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20856256 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8440100 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 367794 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25468397 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27005290 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 20157180 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 20157180 — Biomarker: FCGR3A
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16a; FcgammaRIIIa; FcGRIIIA
Study 8636336 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 20216563 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18381791 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29512468 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29042830 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 24492985 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15734768 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 7863824 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20619448 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24516621 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20217071 — Biomarker: ICOSLG mRNA
Type: Predictive Biomarker (PRD)
Genes: ICOSLG; B7H2; B7RP1; ICOSL; KIAA0653
Study 20217071 — Biomarker: TCF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCF3; BHLHB21; E2A; ITF1
Study 20217071 — Biomarker: VCAM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VCAM1
Study 20217071 — Biomarker: CCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR1; CMKBR1; CMKR1; SCYAR1
Study 20217071 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 16183965 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 2466846 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 28329240 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 19567927 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15019657 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30645844 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30645844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30645844 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30645844 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15246968 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 26739683 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 26739683 — Biomarker: SYK mRNA
Type: Predictive Biomarker (PRD)
Genes: SYK
Study 17394642 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 17394642 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 7956714 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 7956714 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 25287712 — Biomarker: PPARGC1A mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1
Study 16340944 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 16340944 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 16340944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15037537 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 11130772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11130772 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8286176 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 29330312 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26916697 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26916697 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 12860576 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10583711 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 31755526 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 18853090 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15126520 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15126520 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9543436 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28578208 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 28578208 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 8797143 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1480537 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29696916 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29696916 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 29696916 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27170340 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31669496 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19080093 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20110750 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20110750 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11452703 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 24372522 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24372522 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24372522 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24372522 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12134181 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7753965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19767796 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14985687 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11583721 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20029334 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 17145061 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 15229337 — Biomarker: CYP19A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 15229337 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 31985099 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 31668885 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 26498227 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 21549465 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 21549465 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19438397 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9669447 — Biomarker: CAMP mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMP; CAP18; FALL39; HSD26
Study 9669447 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21228822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31200814 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 28760787 — Biomarker: NISCH mRNA
Type: Predictive Biomarker (PRD)
Genes: NISCH; IRAS; KIAA0975
Study 23663881 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17374672 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17374672 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9141919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8179165 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25520127 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 3893343 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8031109 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23250821 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18438829 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 7861873 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22139541 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17684211 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3308164 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20804255 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8726671 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1928809 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25118980 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18801760 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15105384 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 20818862 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 20818862 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11078282 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11078282 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31662515 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 31662515 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31662515 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 29895587 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29895587 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25282317 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25282317 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19449118 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 19449118 — Biomarker: MAEA mRNA
Type: Predictive Biomarker (PRD)
Genes: MAEA; EMP; HLC10; PIG5
Study 19449118 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 15721570 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 12049621 — Biomarker: EDNRA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDNRA; ETA; ETRA
Study 12049621 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 10439495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2105625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26744141 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19826288 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24836125 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24836125 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22733440 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18230966 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3563121 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29701042 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 29701042 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27316324 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23931043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23931043 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 20099160 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14983963 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 23254592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23254592 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23254592 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21364610 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7334934 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 31503258 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 25040143 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17875948 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17875948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11297574 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11297574 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11297574 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9208491 — Biomarker: TMEM37 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMEM37; PR
Study 1443204 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30714486 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 28724185 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 16873344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10193813 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 10193813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7053160 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18534087 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12885990 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 11789186 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11526545 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 27433861 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22990352 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12548129 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7720762 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30817251 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30817251 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24282136 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20515580 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18831357 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2128415 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 31690303 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31690303 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25313573 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 18046108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10090337 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10090337 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 1969115 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28324265 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23742877 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 14615734 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14615734 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30412061 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25686644 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 11061474 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22965622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1559504 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18398944 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18398944 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9759992 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27223846 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 20506355 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11048472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29324186 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 22574589 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 22574589 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22574589 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22574589 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 22574589 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10323426 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21975348 — Biomarker: GPR119 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPR119
Study 21975348 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 21975348 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 6319452 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18336635 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 16861420 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 16861420 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 12874612 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22560357 — Biomarker: NR4A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR4A3; CHN; CSMF; MINOR; NOR1; TEC
Study 31013182 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 20596692 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20596692 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 7752328 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17255299 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9713297 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27480340 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 27480340 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9442424 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 7954041 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7954041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22342928 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 20213795 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15932816 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 11464953 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 11464953 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 3533566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24669646 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12816171 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8788540 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29183775 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)