AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 22549509 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 22549509 — Biomarker: NR3C1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR3C1; GRL
Study 11926786 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 9074719 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1680616 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 27267255 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 23965751 — Biomarker: Urine free cortisol
Type: Surrogate Endpoint (SUR)
Study 9573535 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19478464 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19478464 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15536108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3118453 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3118453 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31504461 — Biomarker: SIGLEC5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIGLEC5; CD33L2; OBBP2
Study 31504461 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 27533954 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20947211 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11329461 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26337521 — Biomarker: BNC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BNC1; BNC
Study 7610928 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8549036 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 11776302 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 11776302 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 8827777 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 22513288 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22513288 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22513288 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20044806 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 28974553 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 21837450 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 17470161 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7541235 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7541235 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 26270693 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 10395845 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10395845 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 10395845 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 10395845 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 7477616 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7372824 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 23432528 — Biomarker: Platelet count response
Type: Surrogate Endpoint (SUR)
Study 21347869 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21347869 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 9040451 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9040451 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7935657 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31706622 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 25773607 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 25773607 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17161766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17161766 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 9187435 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 24504700 — Biomarker: CXCR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR2; IL8RB
Study 21989324 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19942479 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19942479 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 12695416 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10824628 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 10824628 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8870755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19177538 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7489530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30762267 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30762267 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30762267 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17245230 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17245230 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17245230 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15911866 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 7613151 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7613151 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 7613151 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 23480640 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8614309 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24332687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19726349 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16301340 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2146996 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 24145207 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 19070440 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27080156 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22257577 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 15797163 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2050319 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 1101478 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 31283908 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 26334853 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 23004922 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10929272 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20969725 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15547093 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11560099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26430087 — Biomarker: APOL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOL1; APOL
Study 3823635 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29110150 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11919119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10232685 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29908832 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 31907125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31907125 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10682110 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 2283647 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 218427 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 218427 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24523431 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24523431 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23896377 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 17675341 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12202092 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 9832115 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21636183 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18175066 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study 17205814 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29228147 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26247967 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26247967 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26247967 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24284085 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 17611715 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 16553681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14610097 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27380647 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 30904691 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 26667034 — Biomarker: DBH mRNA
Type: Predictive Biomarker (PRD)
Genes: DBH
Study 24767620 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18046973 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18046973 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12522468 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20560910 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 16928710 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 9933750 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 2186867 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2186867 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25887344 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 15589857 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15589857 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15589857 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 15589857 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11320497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25673568 — Biomarker: ABCG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 25673568 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 16316966 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 28265180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25112009 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19618315 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 19618315 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 19618315 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 19332730 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19332730 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19332730 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 12106935 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2206783 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31930892 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 19950091 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19950091 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 17323226 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 15310081 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28650919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11164425 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 11164425 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9342067 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9342067 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2870732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20860413 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20860413 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18090355 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18090355 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 10950768 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18931219 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 9203934 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 29766330 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 25359435 — Biomarker: SP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP2; KIAA0048
Study 22735801 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 6400110 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28622463 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28622463 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8275438 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8275438 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8275438 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8275438 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 30664549 — Biomarker: TRPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPA1; ANKTM1
Study 30664549 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 30664549 — Biomarker: TRPM8 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPM8; LTRPC6; TRPP8
Study 17067136 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17067136 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8551420 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 30132262 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30132262 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28471773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19000552 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 11187921 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 11187921 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18226670 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31879229 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 27382456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24802951 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 30661700 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24055350 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 23327034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18806966 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23218453 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 11544618 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27716201 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18031594 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19409854 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26490434 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 9275134 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 28814805 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 28814805 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 16987866 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 25961461 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 25961461 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 12581972 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2258780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20950166 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14616834 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 14616834 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 6184564 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26031399 — Biomarker: FGR mRNA
Type: Predictive Biomarker (PRD)
Genes: FGR; SRC2
Study 15083370 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 11435508 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 11435508 — Biomarker: ABCC6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC6; ARA; MRP6
Study 11435508 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11435508 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11271223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21215482 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22588495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17591527 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17591527 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17591527 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16318141 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 12175313 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8595506 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27270841 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22929458 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22929458 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12665974 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1530141 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26571136 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26571136 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18675745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10634391 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)