AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 9174136 — Biomarker: MHC class I polypeptide-related sequence A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MICA; PERB11.1
Study 25472825 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23433852 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23433852 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17301824 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 17301824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9932142 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8050541 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 30659070 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25666215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21311168 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 19338158 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 19338158 — Biomarker: FGR mRNA
Type: Predictive Biomarker (PRD)
Genes: FGR; SRC2
Study 16412750 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 16412750 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 16412750 — Biomarker: ERBB4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB4; HER4
Study 12587182 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 12587182 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9577356 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30355512 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 11905959 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29164399 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 24692284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22687601 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12784171 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10561205 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31022110 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22336878 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17589194 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12544376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8847874 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2941372 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25643617 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 19584736 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 26920896 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26920896 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26920896 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26920896 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 22413021 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 22413021 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22413021 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 22413021 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 18980783 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study 12611908 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 30939189 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25147806 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17953679 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 24598306 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17150108 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 27228435 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24687165 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7780069 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2109023 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2109023 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 2109023 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 14979213 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9220179 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3329738 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 29570588 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 22672501 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 22672501 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22672501 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22672501 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 3327931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3327931 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31389672 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 25680623 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 24156558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16918261 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study 28453759 — Biomarker: CCR9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR9; GPR28
Study 28453759 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28453759 — Biomarker: CCL25 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL25; SCYA25; TECK
Study 28453759 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 26222774 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 12090818 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1951147 — Biomarker: TEF mRNA
Type: Predictive Biomarker (PRD)
Genes: TEF; KIAA1655
Study 29061621 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 29061621 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25392341 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 24811963 — Biomarker: Insulin receptor substrate 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IRS1
Study 11222112 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 9603683 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30943497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29208690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23141486 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23141486 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 18713842 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25455421 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25455421 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23292038 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15592329 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11359439 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11359439 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 11359439 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 7937908 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 3218660 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3218660 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21346512 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10894321 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7402771 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30481106 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 9918518 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17186304 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8219679 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8219679 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 27180890 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 27180890 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 23394782 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 31174586 — Biomarker: LGI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LGI1; EPT; UNQ775/PRO1569
Study 27085996 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15957834 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12060619 — Biomarker: PSCA mRNA
Type: Predictive Biomarker (PRD)
Genes: PSCA; UNQ206/PRO232
Study 7703389 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30843481 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20178563 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20178563 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20178563 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 10431992 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 21088253 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 18440147 — Biomarker: TRPM8 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPM8; LTRPC6; TRPP8
Study 18440147 — Biomarker: TRPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPA1; ANKTM1
Study 10846036 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2878747 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 25778646 — Biomarker: FAS mRNA
Type: Predictive Biomarker (PRD)
Genes: FAS; APT1; FAS1; TNFRSF6
Study 19469405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11961630 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10404953 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23933474 — Biomarker: UCN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCN3; SPC
Study 18362418 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18362418 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16485520 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12095184 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8154311 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31462727 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31462727 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 18179556 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18179556 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 18179556 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18179556 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16598749 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 2439814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27773406 — Biomarker: RHD mRNA
Type: Predictive Biomarker (PRD)
Genes: RHD
Study 20427668 — Biomarker: POMC mRNA
Type: Predictive Biomarker (PRD)
Genes: POMC
Study 20427668 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 16162204 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23370835 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21610516 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 26585569 — Biomarker: MAG mRNA
Type: Predictive Biomarker (PRD)
Genes: MAG; GMA
Study 26865338 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 14624169 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17660031 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15957832 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15957832 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2209678 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7470854 — Biomarker: SLC10A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC10A3; DXS253E; P3
Study 2688586 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1081271 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7700070 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19731193 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16548349 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 12963608 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 31210529 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 27436584 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 27436584 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 22172468 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 12692805 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 10871712 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24970858 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10965418 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20640584 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 7494588 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 23461723 — Biomarker: NRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRP1; NRP; VEGF165R
Study 16682542 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 11369986 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9160527 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 18252894 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9003110 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27274999 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27256731 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 27256731 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 23017356 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 23017356 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 23017356 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 26263223 — Biomarker: GNPDA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNPDA2; GNP2
Study 26263223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17473202 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 17473202 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15185770 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 15185770 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9822092 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2572566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18329197 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 24755130 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24755130 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 17227801 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30283911 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16604131 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 9424322 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9424322 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28762106 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22283559 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 14564591 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1705140 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 25936324 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 25936324 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21946197 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 3605735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25645987 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 24171516 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 19766757 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14995938 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11746538 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9541692 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 30810619 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21550429 — Biomarker: DKK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DKK1; UNQ492/PRO1008
Study 21550429 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 21550429 — Biomarker: E2F1 mRNA
Type: Predictive Biomarker (PRD)
Genes: E2F1; RBBP3
Study 12686335 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7606629 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28762606 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18004611 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14555563 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 25922062 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27045034 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24578135 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 22925537 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22925537 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22925537 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27801706 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9211578 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 28892591 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28892591 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 18034777 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 11074199 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 27401892 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 27216240 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24713285 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1113235 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 30958045 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30958045 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 20940336 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9