AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 18514630 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7793203 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18580852 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 18580852 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 18580852 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18580852 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 18580852 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 18580852 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study 21371282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19621985 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16988754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10342818 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8728305 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study 8728305 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25098557 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 21900837 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 15983826 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 11997270 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11997270 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28682871 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 28682871 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 20709498 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30668196 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 30668196 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 19103558 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15385732 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 15385732 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 29352071 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 29352071 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 27510532 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28822007 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 24227635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19523596 — Biomarker: PAFAH1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study 12730797 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1736933 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29969473 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29969473 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 26407603 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 26407603 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22683955 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22683955 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 11177189 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 26477027 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29264937 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 11247403 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 9262430 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9262430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9262430 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 30144513 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 30144513 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12929292 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 8843769 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 21057977 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 282700 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16480566 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 12871871 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30849931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27697868 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20501479 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8522408 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 2678209 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7837863 — Biomarker: DPT mRNA
Type: Predictive Biomarker (PRD)
Genes: DPT
Study 11230838 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3055923 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31811995 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31811995 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23277482 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 8670317 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 30426791 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27347650 — Biomarker: ACTG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACTG1; ACTG
Study 31855906 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 28886992 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 28886992 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28886992 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26123410 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 28598231 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28598231 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17853751 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 30458778 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24239324 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 28343659 — Biomarker: DMA mRNA
Type: Predictive Biomarker (PRD)
Genes: DMA; HLA-DMA; hCG_2001572
Study 12603860 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10934653 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10934653 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 10934653 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8165610 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 8165610 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8165610 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 19255393 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17061441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11697840 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10970684 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10970684 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8792771 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 1467127 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 6419809 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16000966 — Biomarker: REST mRNA
Type: Predictive Biomarker (PRD)
Genes: REST; NRSF; XBR
Study 29209783 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8554929 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2316590 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6299842 — Biomarker: NFU1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NFU1; HIRIP5; CGI-33
Study 19327620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16447051 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 17805229 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16148211 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 12790209 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9023716 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9023716 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7505008 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 2881786 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27504914 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19404392 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11149996 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 7584951 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 7584951 — Biomarker: CFTR
Type: Predictive Biomarker (PRD)
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 31027477 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25791173 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 3743860 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27955663 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21132128 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1730841 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 6486559 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30270639 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 30270639 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 21095280 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 10781471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3883734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20087785 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 12479668 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 31149842 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14640255 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14640255 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26066335 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26066335 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 24476477 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 24476477 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 19364302 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 9364979 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 29567321 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24475777 — Biomarker: AQP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP4
Study 22268125 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 18180567 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 12512229 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12512229 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 7695972 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 24045793 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 19549707 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 7870637 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 7870637 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20643762 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 15937580 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 8899091 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 30431588 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 30431588 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 21913966 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20225658 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7598919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31888605 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 9281254 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 9281254 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 8193733 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29508153 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29508153 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 7898088 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7898088 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11049919 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11049919 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30201310 — Biomarker: TCP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCP1; CCT1; CCTA
Study 23257008 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23257008 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2045865 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31261967 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17520105 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17520105 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11336714 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31406997 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 31406997 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 31406997 — Biomarker: TLR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR5; TIL3
Study 31406997 — Biomarker: MAP3K7 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP3K7; TAK1
Study 31406997 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31406997 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 24625704 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 7752862 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31525164 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 25986458 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12820919 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 1794742 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 1794742 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1794742 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30947751 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 23184120 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29445029 — Biomarker: SLC22A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A2; OCT2
Study 29445029 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 14498766 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10875526 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29330008 — Biomarker: SPN mRNA
Type: Predictive Biomarker (PRD)
Genes: SPN; CD43
Study 15139775 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11773939 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2674713 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2674713 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31177183 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 25637266 — Biomarker: NE
Type: Predictive Biomarker (PRD)
Study 2285608 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 28166816 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 26063161 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 18758699 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16644608 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8651712 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22891946 — Biomarker: Apolipoprotein A-IV
Type: Monitoring Biomarker (MOI)
Genes: APOA4
Study 22891946 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22891946 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20164553 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 7461012 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31744796 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 31744796 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 26001320 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26866954 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 26866954 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1577054 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 21944176 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21944176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16846541 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7840053 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7840053 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 2369312 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18524974 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14653835 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 23925644 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 15958628 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10501821 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 30499486 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17628912 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 17882685 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15083368 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15083368 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27771172 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27771172 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24467669 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24467669 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)