AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 12103457 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2649632 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 2649632 — Biomarker: Serum phosphate
Type: Surrogate Endpoint (SUR)
Study 14514648 — Biomarker: GAD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD2; GAD65
Study 9625405 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16255837 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16255837 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11552710 — Biomarker: CYP17A1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CYP17A1; CYP17; S17AH
Study 11552710 — Biomarker: CYP1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A1
Study 31639790 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31639790 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 21654719 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21654719 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18475154 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21757893 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21757893 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21757893 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15149875 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 15149875 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15149875 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8204472 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29184167 — Biomarker: NEB mRNA
Type: Predictive Biomarker (PRD)
Genes: NEB
Study 29184167 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29184167 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25403327 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25403327 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 25403327 — Biomarker: ADGRE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADGRE1; EMR1; TM7LN3
Study 25403327 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 17559750 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2745320 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22594233 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 12218231 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 9856368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2133226 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24197772 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 20082737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31473172 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 29882843 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20979906 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12147929 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12147929 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10358862 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1782973 — Biomarker: VEZF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VEZF1; DB1; ZNF161
Study 23715753 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 31254718 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2887186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8201963 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 2906873 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25506778 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25506778 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21761129 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 18320559 — Biomarker: DRD3
Type: Safety Biomarker (SAF)
Study 3519694 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30557404 — Biomarker: Cyclin-dependent kinase inhibitor 1
Type: Safety Biomarker (SAF)
Genes: CDKN1A
Study 22490477 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 937076 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 28157728 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 27009270 — Biomarker: VCP mRNA
Type: Predictive Biomarker (PRD)
Genes: VCP
Study 16142873 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30571192 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 30571192 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23710734 — Biomarker: BOC mRNA
Type: Predictive Biomarker (PRD)
Genes: BOC; UNQ604/PRO1190
Study 25361222 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25361222 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26095784 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16899031 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 7956627 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 31230825 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 31230825 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 17890465 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 26010368 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 21830080 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 19575270 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26911532 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17914251 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 16981274 — Biomarker: GLS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS2; GA
Study 12604410 — Biomarker: HDC mRNA
Type: Predictive Biomarker (PRD)
Genes: HDC
Study 3924425 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 3924425 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16136771 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 10599797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7275464 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 24165020 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 24165020 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17714121 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 8749687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16424649 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 11006039 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 6337767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6337767 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 26143741 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 22341868 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17343662 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15881488 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19195263 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17825150 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 17825150 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17825150 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15106795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11252223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7861719 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 412450 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 23448807 — Biomarker: PSCA mRNA
Type: Predictive Biomarker (PRD)
Genes: PSCA; UNQ206/PRO232
Study 21368751 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 939070 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30910592 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 30910592 — Biomarker: SOX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOX2
Study 30910592 — Biomarker: ALDH1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH1A1; ALDC; ALDH1; PUMB1
Study 20430601 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 6127719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25896973 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25896973 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 25896973 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 25896973 — Biomarker: PALB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PALB2; FANCN
Study 7528271 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9177508 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 15591335 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9024169 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 30545338 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 30967589 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 26803431 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26803431 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26803431 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26803431 — Biomarker: Urokinase plasminogen activator surface receptor
Type: Monitoring Biomarker (MOI)
Genes: PLAUR; MO3; UPAR
Study 26803431 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20661086 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20661086 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 12039990 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31187152 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 25268043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21350408 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study 21350408 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 24355241 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 11004039 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 11004039 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8625683 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 27495291 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7946856 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10739392 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 29624540 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 29624540 — Biomarker: Auditory steady-state response
Type: Pharmacodynamic Biomarker (PDY)
Study 31226526 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 11092646 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11092646 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11092646 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11092646 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 11092646 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 31689326 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 27627098 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27627098 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 28844499 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 28844499 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 28844499 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21406671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17381964 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 31888762 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31888762 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31888762 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24862674 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 7780288 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 344012 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23529567 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 26444095 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 26444095 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15572523 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 9952095 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7402449 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15360029 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 11677377 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11677377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22669588 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 31035665 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 22473458 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22473458 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3993545 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29946115 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29946115 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29946115 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14688021 — Biomarker: SULT1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SULT1A1; STP; STP1; OK/SW-cl.88
Study 9331014 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28972039 — Biomarker: WT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WT1
Study 28972039 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16343130 — Biomarker: CFL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CFL1; CFL
Study 10467830 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 10467830 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 536969 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24210087 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 24210087 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11402974 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9124466 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 24949820 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12482641 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 11395985 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8383397 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8383397 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20825071 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20825071 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12674340 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25873553 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25873553 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21075774 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17224434 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2405613 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22041323 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22041323 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 8857279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2001053 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29382142 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23945720 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11302998 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1887747 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28199736 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28199736 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 28199736 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22397264 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19715914 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 19715914 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19715914 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11581559 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 11581559 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9886905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29688617 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 27100393 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 27100393 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27100393 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27100393 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19455040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12118835 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9361169 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 30115826 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 30115826 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 25716546 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 22762867 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 24131872 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24131872 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)