AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 28330908 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25908673 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 19711453 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19711453 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 7882602 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9122001 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 9122001 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 22741259 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11973193 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19188877 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 15342805 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11773946 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11773946 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 11773946 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study 11773946 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9553680 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8713783 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30576246 — Biomarker: CISH mRNA
Type: Predictive Biomarker (PRD)
Genes: CISH; G18
Study 10225769 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 10225769 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16246964 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 12072897 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 12072897 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24763694 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 3187474 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16205558 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 16205558 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 7749987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17651518 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27824234 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27824234 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27824234 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26717366 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 26717366 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22577293 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 22577293 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 32007 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30649176 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26362830 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7797214 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 3044068 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31909680 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26602302 — Biomarker: EED mRNA
Type: Predictive Biomarker (PRD)
Genes: EED
Study 24341382 — Biomarker: CXCR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR2; IL8RB
Study 24341382 — Biomarker: CXCL1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 24341382 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 16484584 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 12916867 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25722222 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 25722222 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 1514487 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30765435 — Biomarker: GCGR mRNA
Type: Predictive Biomarker (PRD)
Genes: GCGR
Study 15024927 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 6125727 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24979307 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24979307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30817452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17564405 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 30063804 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 30063804 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 24535626 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24535626 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 10442596 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15958169 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6782869 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6782869 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 24534379 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 30352748 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30352748 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30191830 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27130691 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 27130691 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 21162959 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21162959 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17670801 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29216945 — Biomarker: GATA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GATA3
Study 29216945 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 10760105 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1569387 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 30634393 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21307868 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 21307868 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21307868 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18555744 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18555744 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18555744 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18555744 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28291486 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11093066 — Biomarker: ABCG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG1; ABC8; WHT1
Study 8350608 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 8678631 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 7060323 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28292758 — Biomarker: PDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PDK4; PDHK4
Study 28292758 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 28292758 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 28292758 — Biomarker: IRS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRS2
Study 28292758 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 28292758 — Biomarker: Insulin receptor substrate 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IRS1
Study 25773888 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 23462922 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 19098490 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7044523 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24406207 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15475601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7001898 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31729126 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31729126 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16583374 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study 1616360 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6085189 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 31240605 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 10495460 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 30753650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22954674 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 20082714 — Biomarker: INPP5K mRNA
Type: Predictive Biomarker (PRD)
Genes: INPP5K; PPS; SKIP
Study 12232494 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10421283 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21268411 — Biomarker: CMAS mRNA
Type: Predictive Biomarker (PRD)
Genes: CMAS
Study 17879527 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17879527 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10051803 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 22907764 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 22907764 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 11282170 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 11282170 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 3653122 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31797417 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26327495 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 15930485 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15930485 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6367578 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29432383 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 16636856 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 11834238 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 18697183 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18697183 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18697183 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16595786 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12411756 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30055883 — Biomarker: MCCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCCC2; MCCB
Study 21036743 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 21036743 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 21036743 — Biomarker: NRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRP1; NRP; VEGF165R
Study 21036743 — Biomarker: FCGR3A mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 28915863 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23159770 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 18198263 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18198263 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22340260 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 30186593 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 11668667 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 31539025 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12833465 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 30848697 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 28437264 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12924170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8331700 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8331700 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10896693 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 8941104 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27604993 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24100150 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 16052573 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24937546 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 16088297 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16088297 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16088297 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16088297 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31571243 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31571243 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 31571243 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31204146 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 28930174 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28930174 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21747355 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21747355 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9129558 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9129558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3372076 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25875447 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7810285 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2843722 — Biomarker: SERPINA7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA7; TBG
Study 31308062 — Biomarker: KLRD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRD1; CD94
Study 31308062 — Biomarker: KLRC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRC1; NKG2A
Study 21632509 — Biomarker: TLR9
Type: Predictive Biomarker (PRD)
Genes: CD289
Study 1627944 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 1627944 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 1627944 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 1627944 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 26282726 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20139920 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20139920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20139920 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20139920 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 20139920 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 18264747 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12823597 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 6797778 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23715889 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 11431176 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11431176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28596379 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 28596379 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 22224109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12876635 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12876635 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19192047 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30664075 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30664075 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12782545 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 12782545 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11243632 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20433527 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16202859 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24099141 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 21756768 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 18283261 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 18283261 — Biomarker: FER mRNA
Type: Predictive Biomarker (PRD)
Genes: FER; TYK3
Study 18283261 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 26636929 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 26636929 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 26636929 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25237065 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 25237065 — Biomarker: IGFBP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP7; MAC25; PSF
Study 12702905 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 30200935 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24984178 — Biomarker: CYP4F2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP4F2
Study 24984178 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20227347 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8926014 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8926014 — Biomarker: POMC mRNA
Type: Predictive Biomarker (PRD)
Genes: POMC
Study 1905495 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1905495 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 1905495 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23059701 — Biomarker: PICALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PICALM; CALM
Study 17895912 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17895912 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25761367 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 18587236 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18587236 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 8027279 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 21840164 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 31970675 — Biomarker: CHM mRNA
Type: Predictive Biomarker (PRD)
Genes: CHM; REP1; TCD
Study 10548673 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL