AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 22342390 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22342390 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22342390 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 16705003 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 10882616 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8761371 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 8694034 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8694034 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 26234526 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30947915 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21348810 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14617264 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 14617264 — Biomarker: Succinate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: SDHD
Study 21330902 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19815817 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 11977347 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9447290 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 7523548 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 31327563 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 22924607 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 26016510 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 20450723 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20450723 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 28391886 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 28391886 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 28391886 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23065443 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15827399 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 2371368 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 25112699 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 25112699 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 22229802 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9434661 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17876342 — Biomarker: NR1I2
Type: Predictive Biomarker (PRD)
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 17876342 — Biomarker: CXADR mRNA
Type: Predictive Biomarker (PRD)
Genes: CXADR; CAR
Study 17876342 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 12575602 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 28531893 — Biomarker: HTR3A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR3A; 5HT3R; HTR3
Study 20108306 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 17697248 — Biomarker: KCNN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNN3; K3
Study 7485927 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 375435 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28734853 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23909490 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 23909490 — Biomarker: DNA repair endonuclease XPF
Type: Predictive Biomarker (PRD)
Genes: ERCC4; ERCC11; XPF
Study 10543928 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12509376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31871108 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 31871108 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 31871108 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 31871108 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 27140216 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24815795 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 11357167 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 31160807 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 31160807 — Biomarker: IDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH2
Study 31023084 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 31023084 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 16381002 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 16381002 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 31553254 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 25794236 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25794236 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22434756 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 22434756 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 28116886 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28116886 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22967997 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19272441 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25592012 — Biomarker: DHFR mRNA
Type: Predictive Biomarker (PRD)
Genes: DHFR
Study 21924547 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 14974365 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14974365 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 14974365 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 14974365 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 14974365 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11045301 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9363911 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29203092 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29203092 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29203092 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29203092 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 22892814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31988711 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20528002 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22286020 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24112026 — Biomarker: CD74 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD74; DHLAG
Study 21613429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19918023 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 19918023 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 7981558 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 18495465 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 7192456 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31647854 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 31647854 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24365793 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 24365793 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11401008 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 9482137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4157346 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17170610 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28736381 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24827134 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24827134 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 22625844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19741011 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17971594 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15378476 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 12932601 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26845191 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26845191 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8605127 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27304975 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 20032281 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 12622859 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 10638906 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6373155 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10975216 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 10975216 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 20303785 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21132065 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1468291 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 30911301 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 24835324 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17938984 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7729606 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31358107 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31358107 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 18508120 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 20726909 — Biomarker: Coagulation factor Va
Type: Safety Biomarker (SAF)
Genes: F5
Study 9613225 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 9613225 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 22578232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20929464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16204712 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 17610024 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17610024 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 813120 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28711582 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 19779464 — Biomarker: ADRB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB1; ADRB1R; B1AR
Study 19779464 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 19779464 — Biomarker: SLC12A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC12A3; NCC; TSC
Study 16450155 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16450155 — Biomarker: GNB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNB3
Study 16450155 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 8874308 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8664131 — Biomarker: DDC mRNA
Type: Predictive Biomarker (PRD)
Genes: DDC; AADC
Study 1839902 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24418244 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 22088518 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 22088518 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 17003569 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15259448 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8471406 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8471406 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2869849 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30315150 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 23417688 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20560730 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18627322 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18627322 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10234895 — Biomarker: STAR mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAR; STARD1
Study 30268865 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 28198147 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19076137 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11398518 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 26771632 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22387276 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 22387276 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 7717564 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14666758 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15215792 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16405436 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11471852 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11471852 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9627123 — Biomarker: HLA-DQB1
Type: Safety Biomarker (SAF)
Genes: IDDM1; CELIAC1
Study 18494215 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18494215 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26135463 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8467308 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20436237 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11801262 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11801262 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 21897852 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10436958 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 10436958 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25604769 — Biomarker: C-C motif chemokine 7
Type: Predictive Biomarker (PRD)
Genes: CCL7; MCP3; SCYA6; SCYA7
Study 19332209 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19332209 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16968790 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11393553 — Biomarker: DPT mRNA
Type: Predictive Biomarker (PRD)
Genes: DPT
Study 26791478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24361280 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22620695 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 17070596 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 10204726 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2676249 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30335625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21546612 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 25962070 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2968267 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30645203 — Biomarker: C-type lectin domain family 4 member C
Type: Pharmacodynamic Biomarker (PDY)
Genes: CLEC4C; BDCA2; CLECSF11; CLECSF7; DLEC; HECL; UNQ9361/PRO34150
Study 22779380 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 17187606 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9831973 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9831973 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23785019 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 21083516 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 21083516 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17971525 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 11205424 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20526530 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 16377282 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14645783 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11314241 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 20378094 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 7852604 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 7852604 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2903727 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2903727 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 8514071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26523663 — Biomarker: IPP mRNA
Type: Predictive Biomarker (PRD)
Genes: IPP; KLHL27
Study 23635998 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17198774 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 17198774 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26108190 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 9587116 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 7821189 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 28747245 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21121958 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 18032219 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15617459 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30232857 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30232857 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30232857 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26229089 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26229089 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19508966 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 16118673 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10519562 — Biomarker: DRAM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRAM1; DRAM
Study 10519562 — Biomarker: UBXN11 mRNA
Type: Predictive Biomarker (PRD)
Genes: UBXN11; SOC; UBXD5; PP2243
Study 30100106 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 18727459 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20952427 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 7661492 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)