AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 11258648 — Biomarker: NR3C1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR3C1; GRL
Study 11258648 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11258648 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 11258648 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 11258648 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 11258648 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11258648 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 11258648 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 11258648 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11258648 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 28239907 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23115399 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 17691581 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 17691581 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 17691581 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 11433050 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 15750189 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 12356779 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6318543 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6318543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30646261 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30646261 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31481605 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 17070593 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 1884720 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27040154 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16011198 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16011198 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 21189853 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21189853 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 21189853 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10498024 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 24988179 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9697880 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 9697880 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 9697880 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 2172394 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 1020905 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8620521 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31303526 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 29279062 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 29279062 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29279062 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 24136296 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 30621746 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24252058 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 17951496 — Biomarker: Trefoil factor 3
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TFF3; ITF; TFI
Study 12050266 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12050266 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27644162 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 27644162 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15094937 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 28228317 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 28228317 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 28228317 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15378556 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 9409267 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 9409267 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 9409267 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9409267 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9409267 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 25413264 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18493214 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 18493214 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 18493214 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18493214 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 15799928 — Biomarker: Argininosuccinate synthase
Type: Safety Biomarker (SAF)
Genes: ASS1; ASS
Study 31479209 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 22472069 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 16253098 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 30325687 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 18062059 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 10614063 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 30922259 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26888075 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 6191130 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29973284 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19003734 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 3886142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31569012 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31569012 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 29628009 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29628009 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 29628009 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 27538896 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26527048 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20008640 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 20008640 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 16043675 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 12427118 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study 10072221 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10072221 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10072221 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25816805 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3513519 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31515458 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 2468932 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2468932 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26035255 — Biomarker: SLAMF7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLAMF7; CS1; UNQ576/PRO1138
Study 21288351 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 18727661 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 15323594 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27659879 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31128228 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 19178965 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16484991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7540147 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7540147 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 2025787 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6617110 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25046946 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 29901443 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 20560802 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17697874 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 17697874 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 17697874 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17697874 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17697874 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17697874 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9933654 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3156798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23036264 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23036264 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 23036264 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15265423 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 15265423 — Biomarker: FURIN mRNA
Type: Predictive Biomarker (PRD)
Genes: FURIN; FUR; PACE; PCSK3
Study 30946888 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29165105 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 19046107 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 8335505 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 29596950 — Biomarker: Zinc finger protein GLI1
Type: Predictive Biomarker (PRD)
Genes: GLI1; GLI
Study 29596950 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12546606 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 1930768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31123862 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 9704688 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9704688 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12897178 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 3698693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30975627 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29905969 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26725183 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 25168762 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26419675 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 21077346 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23642942 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23642942 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 23642942 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23642942 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21942957 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25213774 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 22715020 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 22715020 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 30527103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18046432 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28545514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25989216 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 25989216 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25989216 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18638711 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 8807731 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 8807731 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29968397 — Biomarker: GABBR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GABBR1; GPRC3A
Study 31566486 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23815538 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21632099 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 21632099 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8689651 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8689651 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 8689651 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16903977 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16903977 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11525086 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 3129008 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3129008 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27037553 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 16563917 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 16002778 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12601627 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12601627 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 22743678 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12450599 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12450599 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27796775 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 24207163 — Biomarker: PCTP mRNA
Type: Predictive Biomarker (PRD)
Genes: PCTP; STARD2
Study 29673620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21618205 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29329499 — Biomarker: MAP3K10 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP3K10; MLK2; MST
Study 31122178 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 31122178 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 17642239 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 17642239 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28347184 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17566314 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21457273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8739113 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 31544376 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 31544376 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29071848 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30720339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23985432 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8635931 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 17585665 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16271221 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 10209075 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10209075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2143045 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25832995 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21457152 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 21457152 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 30122896 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 25531837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8575573 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23110811 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 15589109 — Biomarker: GCSAM mRNA
Type: Predictive Biomarker (PRD)
Genes: GCSAM; GAL; GCET2
Study 11064501 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8144850 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 3530442 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9234823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8507449 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22362846 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 29247383 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17200730 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 17200730 — Biomarker: WT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WT1
Study 17200730 — Biomarker: IL21
Type: Predictive Biomarker (PRD)
Genes: Za11; IL-21
Study 17200730 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 28855223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26474518 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26474518 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 21609207 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 16460241 — Biomarker: TKT mRNA
Type: Predictive Biomarker (PRD)
Genes: TKT
Study 15288707 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28467869 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24655978 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 17301733 — Biomarker: SLCO1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 17301733 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 31469220 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18822200 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11291603 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8970679 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20428723 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30905227 — Biomarker: TP53INP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TP53INP1; P53DINP1; SIP
Study 10633481 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24038913 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 22561734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8669216 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)