AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 9776437 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20128295 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18200775 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14741066 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14741066 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3029258 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3029258 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29720328 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 9147856 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1491771 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1491771 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 22520669 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22520669 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20479407 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18752330 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10926637 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26721653 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22385885 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22385885 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11035668 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 2580176 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30203681 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 23327035 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23327035 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20573787 — Biomarker: SELENOP mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENOP; SELP; SEPP1
Study 18043579 — Biomarker: TOX mRNA
Type: Predictive Biomarker (PRD)
Genes: TOX; KIAA0808
Study 18043579 — Biomarker: REL mRNA
Type: Predictive Biomarker (PRD)
Genes: REL
Study 21993365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18408049 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 14559315 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14559315 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24941841 — Biomarker: PCSK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK5; PC5; PC6
Study 24941841 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24941841 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16155276 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 12514575 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 8877824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1889971 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 1889971 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 27488365 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 25151492 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 25151492 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25261549 — Biomarker: VGF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: VGF
Study 16202151 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12188390 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31522845 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17578313 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17578313 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 9713009 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21342757 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12730793 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31764461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30998396 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 8672382 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26478104 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 24944137 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24944137 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 18400976 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 14640387 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8648205 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1465689 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25439691 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 25439691 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 1910800 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28157726 — Biomarker: ABAT mRNA
Type: Predictive Biomarker (PRD)
Genes: ABAT; GABAT
Study 28157726 — Biomarker: CNDP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNDP2; CN2; CPGL; HEL-S-13; PEPA
Study 28157726 — Biomarker: SLC15A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC15A2; PEPT2
Study 28157726 — Biomarker: SLC36A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC36A1; PAT1
Study 24083670 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 23630033 — Biomarker: SLC5A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A1; NAGT; SGLT1
Study 23630033 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 23630033 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20126853 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 18046974 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18046974 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2168123 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 31314952 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 31314952 — Biomarker: ASIC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASIC3; ACCN3; SLNAC1; TNAC1
Study 31314952 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 10807760 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28947180 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 18371557 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16368472 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12830471 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8998818 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 26998845 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 26998845 — Biomarker: PTGDS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGDS; PDS
Study 24363029 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16756652 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29642136 — Biomarker: IDE mRNA
Type: Predictive Biomarker (PRD)
Genes: IDE
Study 25326927 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22269152 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22269152 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20303247 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17710485 — Biomarker: PPP1R13L mRNA
Type: Predictive Biomarker (PRD)
Genes: PPP1R13L; IASPP; NKIP1; PPP1R13BL; RAI
Study 15837772 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31768768 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27383196 — Biomarker: miR-192
Type: Safety Biomarker (SAF)
Genes: MIR192
Study 27383196 — Biomarker: miR-375
Type: Safety Biomarker (SAF)
Genes: MIR375
Study 27383196 — Biomarker: miR-21
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR21
Study 11319199 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2894246 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22444829 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 11040249 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23129601 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23129601 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23129601 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23129601 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20704110 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 20704110 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 16236035 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12440353 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7582879 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 26493248 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 24066730 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17234519 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 15200998 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7849542 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 7849542 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29459408 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 26251078 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 20864423 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 20864423 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 9707356 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7536138 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7536138 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 2650539 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2650539 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31102328 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 19153678 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16353616 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16353616 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 16353616 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 25763853 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 23804543 — Biomarker: TNFSF14 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF14; HVEML; LIGHT; UNQ391/PRO726
Study 9092145 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26969090 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26969090 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20485880 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10522523 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25912752 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 21355070 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 21355070 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 21355070 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 21355070 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 10930961 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 10930961 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 8339808 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28234719 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 7977523 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29141361 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29141361 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 29141361 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29141361 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 29141361 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19845453 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17148774 — Biomarker: CDKN1B mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN1B; KIP1; p27
Study 12962749 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7732997 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1682228 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10841922 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 31411039 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 9797622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21806387 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 21806387 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 21806387 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 8466026 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2879477 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29331635 — Biomarker: Chromosome 5q
Type: Predictive Biomarker (PRD)
Study 18774000 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18774000 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 22841694 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16043801 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 26819451 — Biomarker: ITPKB mRNA
Type: Predictive Biomarker (PRD)
Genes: ITPKB
Study 26819451 — Biomarker: MFHAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFHAS1; MASL1
Study 26819451 — Biomarker: TNFAIP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFAIP3; OTUD7C
Study 26819451 — Biomarker: GNA13 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNA13
Study 15481766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16966110 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 22048466 — Biomarker: CHRNB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNB2
Study 22048466 — Biomarker: CHRNA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA5; NACHRA5
Study 22048466 — Biomarker: CHRNA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA4; NACRA4
Study 22048466 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 1315825 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15132405 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27768727 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 11925390 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 11925390 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 10521386 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 11464717 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 11464717 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11464717 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9727375 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9727375 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 7979809 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 28703838 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25226738 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25226738 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20934312 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 16839800 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 12870136 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 21184653 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 21184653 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 19656025 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11152843 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31959233 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29358714 — Biomarker: ADAM10 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM10; KUZ; MADM
Study 29358714 — Biomarker: Amyloid beta peptide (1-40)
Type: Pharmacodynamic Biomarker (PDY)
Genes: APP; A4; AD1
Study 24572041 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24572041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16864147 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16864147 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11930704 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11930704 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11930704 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11930704 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 9773137 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9773137 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 9773137 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 30638420 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28351028 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 19729392 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 31524116 — Biomarker: FFAR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FFAR4; GPR120; GPR129; O3FAR1; PGR4
Study 27720403 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21325298 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 21325298 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 21325298 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 15265408 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15265408 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15265408 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 15265408 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 15265408 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 16336763 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28829051 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 31442298 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 31442298 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21982669 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21982669 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 8621132 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 29961998 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24257390 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 3062906 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 22459275 — Biomarker: FKBP5 mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: FKBP5; AIG6; FKBP51
Study 8677869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31576697 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30032978 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15787663 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10844383 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10844383 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)