AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24219012 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24219012 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22669332 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 20055694 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 24043299 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24043299 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25022932 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18460563 — Biomarker: SOCS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOCS3; CIS3; SSI3
Study 31902294 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 23562090 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 21513812 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21513812 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21513812 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21513812 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16466708 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 16466708 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 14716707 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 9868087 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9868087 — Biomarker: ABCD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCD1; ALD
Study 2827045 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2827045 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30216294 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16174119 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 14652498 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14652498 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 14652498 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10962306 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 8844499 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8844499 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 8844499 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 8844499 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 10815366 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20863381 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10329041 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 16482098 — Biomarker: CCN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 8998115 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 8122598 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2527531 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1071709 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25457473 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17035949 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17035949 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 11258635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9205627 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24661576 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 24661576 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 12370798 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10213650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7788948 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6111161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31324842 — Biomarker: ADORA2A mRNA
Type: Predictive Biomarker (PRD)
Genes: ADORA2A; ADORA2
Study 31324842 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 28492439 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28492439 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15097154 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23613806 — Biomarker: SLC1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC1A2; EAAT2; GLT1
Study 16793845 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 22607852 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16340050 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 7926971 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19948945 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 18544981 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 3524221 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8906519 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8906519 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6127946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31628428 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 21690317 — Biomarker: CHRNA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA3; NACHRA3
Study 21690317 — Biomarker: CHRNA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA5; NACHRA5
Study 16847405 — Biomarker: HFE mRNA
Type: Predictive Biomarker (PRD)
Genes: HFE; HLAH
Study 12742979 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 12742979 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12742979 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 11078176 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 11078176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1458788 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29875287 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28245790 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9323816 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 9323816 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 27072050 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study 20520284 — Biomarker: ABCC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC1; MRP; MRP1
Study 20520284 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 18801964 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 30926576 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25711330 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25711330 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18611338 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18611338 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12756159 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 1873936 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1873936 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26809842 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26809842 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25304843 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 9974404 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 7588500 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 28411872 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19335746 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 11418308 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 9554348 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 30997917 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 28634219 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 26648084 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 26648084 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 7927548 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 26249791 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26249791 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26249791 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24560487 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20951321 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22117718 — Biomarker: HCG22 mRNA
Type: Predictive Biomarker (PRD)
Genes: HCG22; G2; PBMUCL2
Study 22117718 — Biomarker: MUC22 mRNA
Type: Predictive Biomarker (PRD)
Genes: MUC22; G4; PBMUCL1
Study 29951552 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 26704029 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24149007 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17682671 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30290289 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 30290289 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18289163 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 18289163 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22007026 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20868531 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12452760 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8557965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1834592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28272202 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28272202 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 28272202 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 28272202 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28272202 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23429100 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 23429100 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23146135 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 12611772 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1712735 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 23872254 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 19965813 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18759293 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 18759293 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 4002807 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21175438 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 21175438 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21175438 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16427490 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 10929903 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 31050933 — Biomarker: EDAR mRNA
Type: Predictive Biomarker (PRD)
Genes: EDAR; DL
Study 31050933 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 18444445 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 15363826 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15363826 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21438101 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18691705 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8591802 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 8591802 — Biomarker: CCKAR
Type: Safety Biomarker (SAF)
Study 2612091 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 2612091 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2612091 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11403365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11403365 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9814867 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3358819 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3057120 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11709606 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11709606 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11709606 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 8196493 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 30380017 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30380017 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16822845 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11400961 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 30932012 — Biomarker: SLC5A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A5; NIS
Study 30932012 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 23913656 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 21143421 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 8277478 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21806682 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 16227760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11863257 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7747690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6733833 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 6733833 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30761717 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22595172 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22595172 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 19246508 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 26633836 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 26633836 — Biomarker: MEA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MEA1; MEA
Study 22341062 — Biomarker: KCNN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNN3; K3
Study 16130506 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 9284668 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27342654 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27342654 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27342654 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10028925 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1975187 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23955552 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 17174729 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 21044908 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 18551200 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 12906020 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30523029 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 12204864 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9814452 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2713213 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30295425 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29066265 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 29066265 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25361982 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 25361982 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 21593118 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 10904284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10904284 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8462390 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 2939208 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 2939208 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22514244 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15947110 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12067231 — Biomarker: SERPINF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINF1; PEDF; PIG35
Study 25044535 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22414964 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 19082804 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 24919837 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 22727709 — Biomarker: SLC6A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 22727709 — Biomarker: HTR1A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR1A; ADRB2RL1; ADRBRL1
Study 22727709 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 16115902 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10192146 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7755223 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 11504959 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9267921 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27156698 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24685786 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 10029244 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 7601014 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7601014 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30980733 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30980733 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28407247 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28407247 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28407247 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 14660050 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 14660050 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14660050 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 14660050 — Biomarker: ALPK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALPK1; KIAA1527; LAK
Study 2879970 — Biomarker: DHFR
Type: Safety Biomarker (SAF)
Genes: DHFR1
Study 30500138 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1