AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 26494831 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16352688 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9058444 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8436149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28008244 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24916694 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 24916694 — Biomarker: SNAI2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SNAI2; SLUG; SLUGH
Study 24916694 — Biomarker: NRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRP1; NRP; VEGF165R
Study 24916694 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 24916694 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 24916694 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18498909 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1649867 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29768313 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 29768313 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26950829 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 21702254 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25942459 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25942459 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 25942459 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 15837759 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 15837759 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9839106 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 9839106 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18212693 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 11164205 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 28131706 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 26780278 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 16449518 — Biomarker: TFG mRNA
Type: Predictive Biomarker (PRD)
Genes: TFG
Study 10832669 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22731800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8424426 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14515012 — Biomarker: Urine free cortisol
Type: Surrogate Endpoint (SUR)
Study 25465185 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 25465185 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 14691684 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28500214 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21355967 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 19433391 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17024639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2568261 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29777241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16815858 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22428464 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 18490496 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2001777 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31107249 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31107249 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 18042509 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 18042509 — Biomarker: ACTG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACTG1; ACTG
Study 15882297 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7757311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26640058 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 26640058 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 19879683 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19879683 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30148973 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 27895475 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20864808 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20864808 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11085324 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8173687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3781686 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 21641516 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26848258 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 25340768 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 27271310 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24842156 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 21788759 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 15304672 — Biomarker: SLAMF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLAMF1; SLAM
Study 31503275 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 23514667 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23514667 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 18758684 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18758684 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18758684 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 9163637 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 2490824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19931670 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 19931670 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16263778 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27079587 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 15188337 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 4629075 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 29876777 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21219287 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 16461125 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 8218099 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6208103 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31083077 — Biomarker: c-Jun N-terminal kinase
Type: Safety Biomarker (SAF)
Study 26936841 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 22863642 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16315032 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 16315032 — Biomarker: ADRB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB1; ADRB1R; B1AR
Study 16315032 — Biomarker: GNAS mRNA
Type: Predictive Biomarker (PRD)
Genes: GNAS; GNAS1
Study 10203414 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 108461 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 108461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30073224 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 25146586 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19452483 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16036026 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12432502 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 28075064 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21836103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17215657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17215657 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 7921757 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31747677 — Biomarker: ADIPOQ mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 16391903 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 30443999 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 27246305 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 21044248 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 17058270 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 471256 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25581163 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 22522672 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 31875646 — Biomarker: Growth/differentiation factor 15
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 24416905 — Biomarker: SPAG9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPAG9; HSS; KIAA0516; MAPK8IP4; SYD1; HLC6
Study 25573347 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25573347 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9200654 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9200654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28474361 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1755531 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 15022126 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9772930 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17023243 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 1794303 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 3955903 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3955903 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18210330 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10608480 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10608480 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6406531 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 18630541 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 19846027 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 17464087 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15044639 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 8519044 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27424661 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 27424661 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22573135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22573135 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16640106 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12503831 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 7937784 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29535280 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26785764 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26785764 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8625682 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26822542 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25045257 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23684438 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23684438 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19703665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25344737 — Biomarker: REST mRNA
Type: Predictive Biomarker (PRD)
Genes: REST; NRSF; XBR
Study 7663010 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 15863491 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15863491 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23176897 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 19271173 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 19271173 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 16982228 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 16982228 — Biomarker: SERPINA7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA7; TBG
Study 16982228 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study 16982228 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15208650 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 15208650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1696671 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1696671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21248295 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 17588810 — Biomarker: PTMS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTMS
Study 15572757 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30740133 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30740133 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28431800 — Biomarker: PTPRD mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRD
Study 28431800 — Biomarker: LRRC4C mRNA
Type: Predictive Biomarker (PRD)
Genes: LRRC4C; KIAA1580; NGL1; UNQ292/PRO331
Study 28431800 — Biomarker: NRXN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRXN1
Study 28431800 — Biomarker: SLITRK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLITRK1; KIAA1910; LRRC12; UNQ233/PRO266
Study 28431800 — Biomarker: MAGI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAGI1; AIP3; BAIAP1; BAP1; TNRC19
Study 28431800 — Biomarker: MAGI2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAGI2; ACVRINP1; AIP1; KIAA0705
Study 28431800 — Biomarker: NBEA mRNA
Type: Predictive Biomarker (PRD)
Genes: NBEA; BCL8B; KIAA1544; LYST2
Study 28431800 — Biomarker: NRG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study 28431800 — Biomarker: KALRN mRNA
Type: Predictive Biomarker (PRD)
Genes: KALRN; DUET; DUO; HAPIP; TRAD
Study 28431800 — Biomarker: RBFOX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBFOX1; A2BP; A2BP1; FOX1; HRNBP1
Study 28431800 — Biomarker: KCNAB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNAB1; KCNA1B
Study 22798383 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 22798383 — Biomarker: TET1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET1; CXXC6; KIAA1676; LCX
Study 21125811 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21125811 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23838844 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23838844 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 16545434 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8164940 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 31295916 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26009024 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21298654 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21298654 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 21298654 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19026531 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16883221 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 16883221 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16883221 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 16883221 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 16883221 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9010482 — Biomarker: TAC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAC1; NKA; NKNA; TAC2
Study 9010482 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 9010482 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 30528419 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30528419 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27684085 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9052309 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30214183 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 23909452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23909452 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23909452 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23909452 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 21168874 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 17079759 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27002500 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18479773 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 16641918 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12737020 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 12737020 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 23535358 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15282657 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 9285658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29508904 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20036362 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 24369828 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24369828 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16170078 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 16170078 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3068597 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 11461095 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3327846 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 9549737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7860471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26596627 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 6240405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)