AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 7499031 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 7499031 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 6780232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12198018 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10200128 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3969541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26299677 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17012873 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 24593273 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22536073 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22536073 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22536073 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22536073 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12578516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10563072 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1737346 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1737346 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 1737346 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12493085 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 28368672 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 14597860 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14597860 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10954007 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 10954007 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1421877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30107967 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 24330475 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 7880949 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9883403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10631762 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 7595708 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 382821 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30571659 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 28857719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23610455 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19344191 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 11793037 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9408981 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29354950 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23713578 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16239314 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 8305662 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28866091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22412088 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 22412088 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 20079863 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 12504694 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 26112283 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17160498 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 16887430 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 16887430 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15312472 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15312472 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10914936 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 21107327 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21107327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21107327 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 19099689 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 1492852 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 19143907 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 17314057 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12651657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7851372 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 14656749 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 3206197 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 16464519 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2962005 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31952145 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31952145 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 31138315 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15507059 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9270084 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31617649 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31617649 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 28554732 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 28554732 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28554732 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 28554732 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25629740 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20697417 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12577156 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8923356 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 3887852 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26494876 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9237290 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9237290 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9237290 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 9237290 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8338977 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22543739 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22543739 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 22543739 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 17645559 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23765755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21319341 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9707350 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22686074 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31232917 — Biomarker: MLH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MLH1; COCA2
Study 28381198 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 21737787 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 11124134 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10966534 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1609752 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 29167971 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23756850 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10329342 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7866989 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 28142296 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 24685414 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15333734 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 21118735 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 16368293 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16368293 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16368293 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 16368293 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 16368293 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16368293 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 15753186 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10992331 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 27404516 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 24944063 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24944063 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22939358 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8780817 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8780817 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 29710289 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17405995 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 19927136 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15957843 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15957843 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12048138 — Biomarker: APOC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOC3
Study 12048138 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 21292625 — Biomarker: DBI mRNA
Type: Predictive Biomarker (PRD)
Genes: DBI
Study 21158218 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8061720 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15291288 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 3286173 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17313803 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 17313803 — Biomarker: Epithelial cadherin
Type: Predictive Biomarker (PRD)
Genes: CDH1; CDHE; UVO
Study 12682082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24902920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19528834 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22354147 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19005405 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 19005405 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19391530 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 30865529 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30865529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24257813 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 24257813 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 22534049 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19875426 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11207051 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11207051 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 8177971 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8177971 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2444132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1981681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1981681 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 1981681 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 21266204 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 307810 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 24780946 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12969695 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2065688 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 1795202 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1795202 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19222610 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19222610 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8914492 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31471309 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31471309 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 24633809 — Biomarker: NRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRP1; NRP; VEGF165R
Study 24633809 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24633809 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1394200 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 1394200 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 3924065 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 26746868 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16358411 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 16358411 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30538436 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 30538436 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 26915630 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27100654 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 23579624 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21913547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17100775 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17100775 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10897972 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 20530082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16899485 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 10663618 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 38965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28052915 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 19491860 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 22417212 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 22417212 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 1703920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31745073 — Biomarker: ADH1B mRNA
Type: Predictive Biomarker (PRD)
Genes: ADH1B; ADH2
Study 28671332 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 28671332 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25702819 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 23419134 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21953407 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30128934 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 17047171 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17047171 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 14609147 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20200284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18028245 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10423646 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 16733299 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 16733299 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16733299 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11041441 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9377121 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3517554 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20973322 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 20837371 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1436339 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28268084 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21346060 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 21346060 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 21346060 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9144030 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8188397 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8188397 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 8877678 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 22927772 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 22927772 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 30212930 — Biomarker: MAPKAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPKAPK3
Study 30212930 — Biomarker: ARRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARRB2; ARB2; ARR2
Study 30212930 — Biomarker: SLC19A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC19A1; FLOT1; RFC1
Study 30212930 — Biomarker: PRKCD mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKCD; PKCD
Study 30212930 — Biomarker: RHOG mRNA
Type: Predictive Biomarker (PRD)
Genes: RHOG; ARHG
Study 30212930 — Biomarker: PTPN6 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPN6; HCP; PTP1C
Study 30212930 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 30212930 — Biomarker: CNPY3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNPY3; CTG4A; ERDA5; PRAT4A; TNRC5; HSPC084; UNQ1934/PRO4409
Study 30212930 — Biomarker: PYGL mRNA
Type: Predictive Biomarker (PRD)
Genes: PYGL
Study 30212930 — Biomarker: ARNT mRNA
Type: Predictive Biomarker (PRD)
Genes: ARNT; BHLHE2
Study 30212930 — Biomarker: CEBPA mRNA
Type: Predictive Biomarker (PRD)
Genes: CEBPA; CEBP