AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23302544 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18808335 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18808335 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31030100 — Biomarker: NRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRP1; NRP; VEGF165R
Study 21161265 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21161265 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21161265 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 21161265 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 21161265 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 21161265 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 31656059 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 6382224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15951292 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2939008 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24794880 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 7671159 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 7671159 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7671159 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 7671159 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31917283 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 31917283 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 31917283 — Biomarker: ADIPOQ mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 31917283 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15241356 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 15241356 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12618057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31001673 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31001673 — Biomarker: TNFRSF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1A; TNFAR; TNFR1
Study 31001673 — Biomarker: MMP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP7; MPSL1; PUMP1
Study 31001673 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 26990931 — Biomarker: NPL mRNA
Type: Predictive Biomarker (PRD)
Genes: NPL; C1orf13
Study 26990931 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 26990931 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23834392 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23834392 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 7986464 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 2723246 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31876900 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 17077073 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17077073 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11500188 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11500188 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11500188 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 26063762 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21929518 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 17660871 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 8596749 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 25787895 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 21827648 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 14517190 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 9195351 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23058022 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 19534034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17300595 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 11142674 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 15280526 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 31537527 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 31537527 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 27358154 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19204077 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17949325 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 1854464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28877011 — Biomarker: TSLP mRNA
Type: Predictive Biomarker (PRD)
Genes: TSLP
Study 19339704 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8384171 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 26913388 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22420492 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 12577433 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12577433 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 25922285 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 19590447 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15538041 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15538041 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15538041 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 15538041 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1617510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1617510 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1617510 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 29390862 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8709585 — Biomarker: ALDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH2; ALDM
Study 3892220 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1386223 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 30850442 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 25547219 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16237394 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 18024231 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18024231 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12812378 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24082728 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24082728 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24082728 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12959631 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28937828 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 28937828 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 28937828 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 14872155 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28343225 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28343225 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28343225 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26304864 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8706772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6143667 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 6143667 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 6143667 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25041182 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 25041182 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 21153418 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21153418 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23614336 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17413098 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 3330992 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27317632 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20889295 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 9454352 — Biomarker: Argininosuccinate synthase
Type: Safety Biomarker (SAF)
Genes: ASS1; ASS
Study 29769507 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22037055 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 10709884 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12399266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6270809 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24157401 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 31736406 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28458115 — Biomarker: MAP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2
Study 30326124 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25622742 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16928705 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15219522 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15219522 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30642737 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30642737 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 21999374 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study 21999374 — Biomarker: GAL3ST1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAL3ST1; CST
Study 17130417 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 15276488 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8305165 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3545647 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 3545647 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17175645 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17175645 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 11353932 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 11353932 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 11353932 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 15302981 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15302981 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9834279 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23182627 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 16836917 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 16836917 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 9030681 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9030681 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8301102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24831979 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 10682566 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26954978 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26954978 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19487105 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8698447 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30528686 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 1704989 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1704989 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 1704989 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28455996 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28455996 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28455996 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 25826479 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 20008236 — Biomarker: HES1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HES1; BHLHB39; HL; HRY
Study 16973256 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 16973256 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2969320 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2969320 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 2969320 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2969320 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27016296 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 20437326 — Biomarker: GAL3ST1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAL3ST1; CST
Study 10943871 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10943871 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9116921 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 19358978 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 9136830 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 28275109 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 28275109 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 27284930 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 24752831 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8133536 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26940016 — Biomarker: SQSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SQSTM1; ORCA; OSIL
Study 26940016 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 26940016 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 26940016 — Biomarker: TICAM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TICAM1; PRVTIRB; TRIF
Study 20179636 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1839437 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17096182 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 17096182 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11699068 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11699068 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 30958325 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 11733289 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9164221 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8425987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23152373 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16886238 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 11723016 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 11723016 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 11723016 — Biomarker: Coagulation factor Va
Type: Safety Biomarker (SAF)
Genes: F5
Study 8253932 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 29699816 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 29699816 — Biomarker: LIPC mRNA
Type: Predictive Biomarker (PRD)
Genes: LIPC; HTGL
Study 29699816 — Biomarker: FADS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS2
Study 29699816 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27524193 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 23729106 — Biomarker: Lung surfactant protein D
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: SFTPD; COLEC7; PSPD; SFTP4
Study 10372705 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10372705 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 17521243 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 15186950 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 2764533 — Biomarker: CPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPZ
Study 17320192 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 7524278 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 3063290 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 3063290 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3063290 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31121100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31121100 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29233906 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 21235416 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31873085 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 31873085 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 31873085 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 27585503 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31204532 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 30077185 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 10367032 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10367032 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 7547096 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24074269 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10390399 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29510792 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24576868 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12200905 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21884018 — Biomarker: KCNN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNN1; SK
Study 15699486 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2558622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18642654 — Biomarker: NF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF2; SCH
Study 9026268 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)