AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 25223378 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22906144 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17430101 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 8879780 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29664714 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 29664714 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24029392 — Biomarker: PHC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PHC1; EDR1; PH1
Study 23126349 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26631058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26631058 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23769265 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 17204832 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27903997 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 27903997 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27903997 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24738695 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24738695 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 23744760 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19488866 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 19488866 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 19488866 — Biomarker: AFF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AFF1; AF4; FEL; MLLT2; PBM1
Study 19488866 — Biomarker: ETV6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV6; TEL; TEL1
Study 19488866 — Biomarker: TCF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCF3; BHLHB21; E2A; ITF1
Study 19488866 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 18378744 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18378744 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 18378744 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18378744 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28875955 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 28875955 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22912450 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 17456679 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11922396 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8275216 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8275216 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2880603 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2880603 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30647072 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 19842559 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19842559 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15132723 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15132723 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11532054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20146063 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 18490077 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9517592 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 2488113 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31169558 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 31169558 — Biomarker: MAGI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAGI1; AIP3; BAIAP1; BAP1; TNRC19
Study 31169558 — Biomarker: CDKN2A mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2A; CDKN2; MTS1
Study 19567926 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 16877955 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21512411 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 15311720 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15311720 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2946313 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 21272319 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 21272319 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 21272319 — Biomarker: AZGP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AZGP1; ZAG; ZNGP1
Study 14628279 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9714028 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 31515250 — Biomarker: CALR mRNA
Type: Predictive Biomarker (PRD)
Genes: CALR; CRTC
Study 15010034 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10653925 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25032713 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19243818 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 20414637 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 20414637 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18373403 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 18373403 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 9344829 — Biomarker: CFTR
Type: Predictive Biomarker (PRD)
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 25842469 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 20073139 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15562054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29142036 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 22913981 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 20133267 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16710356 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22808020 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21135327 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 17952581 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6138116 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11219482 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2697728 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2697728 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16856900 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 11127214 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 11127214 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11127214 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 30106956 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 22986466 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22986466 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22700888 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 22700888 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 20683945 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 19858400 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22918177 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 10469713 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25296241 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23217889 — Biomarker: STC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STC1; STC
Study 8546884 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23227139 — Biomarker: SYNM mRNA
Type: Predictive Biomarker (PRD)
Genes: SYNM; DMN; KIAA0353; SYN
Study 19577757 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19577757 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10232626 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 6419419 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 29089455 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 26527775 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26527775 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 26527775 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19960973 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19960973 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15077102 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15077102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7522018 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 22818224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22011457 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 15954968 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15954968 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7795987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27895044 — Biomarker: GNAS mRNA
Type: Predictive Biomarker (PRD)
Genes: GNAS; GNAS1
Study 27895044 — Biomarker: GNB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNB3
Study 27895044 — Biomarker: GNAQ mRNA
Type: Predictive Biomarker (PRD)
Genes: GNAQ; GAQ
Study 16208088 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7768079 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20715733 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 29633507 — Biomarker: Plasma testosterone level
Type: Surrogate Endpoint (SUR)
Study 24316088 — Biomarker: PRF1
Type: Predictive Biomarker (PRD)
Genes: PFP; P1; HPLH2
Study 1887821 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31601239 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24491874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20970650 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 16844623 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16844623 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 12925471 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1799190 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24910270 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19828909 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 11900495 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 2330930 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 25652873 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25652873 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 21454745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7702060 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7702060 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21653990 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19342867 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16188495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16188495 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10687746 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25496514 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 18712038 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18712038 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18712038 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10477009 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 10477009 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 10477009 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 30312423 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28315479 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 1745709 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22832261 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18989229 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12117739 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12117739 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12117739 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 12117739 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 12117739 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12117739 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19195498 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19195498 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12958326 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31898965 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30501618 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15571210 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15571210 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15571210 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11731753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27496680 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20808331 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14551179 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 14551179 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 14551179 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8695243 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 8695243 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 8695243 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 1839981 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 20200939 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15674304 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15674304 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21054554 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 15146102 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11593317 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26377342 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21736934 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 12900588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9371668 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2006660 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22385260 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 22385260 — Biomarker: LRIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LRIT1; LRRC21; PAL
Study 19048594 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 15181067 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 3706675 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27213735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24151982 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 24151982 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20971614 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 16908486 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 16908486 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15114598 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 11710402 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9020286 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 9020286 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 3297732 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29245259 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23507773 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 21554245 — Biomarker: KLRG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRG1; CLEC15A; MAFA; MAFAL
Study 21554245 — Biomarker: KLRK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRK1; D12S2489E; NKG2D
Study 15816266 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 12575585 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9040055 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 27632917 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16188920 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26440134 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 24140664 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 1994935 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20646010 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9088586 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 9088586 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 9088586 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 20923370 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 1350264 — Biomarker: Hypoxanthine-guanine phosphoribosyltransferase
Type: Safety Biomarker (SAF)
Genes: HPRT1; HPRT
Study 6756932 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30817733 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24672936 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24672936 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 22051941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22051941 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26141671 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26141671 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26141671 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16893754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1900384 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1900384 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6829485 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)