AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23867841 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23867841 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14644854 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23570501 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 23570501 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23570501 — Biomarker: TOP2A mRNA
Type: Predictive Biomarker (PRD)
Genes: TOP2A; TOP2
Study 19185642 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19185642 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 19185642 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19185642 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19185642 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19185642 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 17431226 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17133300 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1904354 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 29471839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22956509 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 22956509 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17934830 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 10596994 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1992363 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 17573745 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8507122 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8507122 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3034026 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3034026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25079863 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 18480672 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9371346 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3758141 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 3758141 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31663690 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 20934440 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16434463 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11306523 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2906248 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30655188 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30232597 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23819122 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19922034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19922034 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19922034 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19922034 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19922034 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20628405 — Biomarker: HFE mRNA
Type: Predictive Biomarker (PRD)
Genes: HFE; HLAH
Study 11166781 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11166781 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7913970 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3061974 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3061974 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29949232 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27912901 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 15179410 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 15179410 — Biomarker: CYP2E1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2E1; CYP2E
Study 15179410 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 15179410 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 15179410 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 12211668 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26505413 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 15192321 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15192321 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 30047176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25322597 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21297492 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21297492 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21297492 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 21297492 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19076931 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8673544 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24500308 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 24500308 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 19669013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15592273 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8196140 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 30795802 — Biomarker: HTRA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HTRA1; HTRA; PRSS11
Study 18470666 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2683758 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2683758 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 1089438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31177752 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31177752 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19857084 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19857084 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19857084 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 16707546 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26767384 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 18458698 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11004136 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 8968265 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29691233 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 29691233 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 29691233 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 26708636 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15759292 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 30268481 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 10351969 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 26337820 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26337820 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29520926 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 26948366 — Biomarker: TERT mRNA
Type: Predictive Biomarker (PRD)
Genes: TERT; EST2; TCS1; TRT
Study 26948366 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 23734703 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20416080 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20416080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8652950 — Biomarker: TYMS
Type: Predictive Biomarker (PRD)
Genes: Tsase; TMS; HsT422
Study 28130918 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 23766507 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11354519 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29739677 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29739677 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3310827 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27042166 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19086719 — Biomarker: ARX mRNA
Type: Predictive Biomarker (PRD)
Genes: ARX
Study 31117835 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12575603 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 18394829 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 24534270 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10919601 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24835503 — Biomarker: PLN mRNA
Type: Predictive Biomarker (PRD)
Genes: PLN; PLB
Study 28510573 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 23625101 — Biomarker: COPE mRNA
Type: Predictive Biomarker (PRD)
Genes: COPE
Study 20573162 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11512247 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9766455 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 3046630 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15248191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9710010 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 2837895 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29415837 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 16940442 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 24925090 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 12485511 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 9802273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6335005 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30500110 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 18338627 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15847251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12774056 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10420392 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 10420392 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 30688377 — Biomarker: PTN mRNA
Type: Predictive Biomarker (PRD)
Genes: PTN; HBNF1; NEGF1
Study 14636905 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14636905 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29641281 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27263311 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27263311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22765917 — Biomarker: CA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA1
Study 22765917 — Biomarker: CA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA3
Study 1659172 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30554611 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30027496 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 21476945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17567421 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31826682 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12964065 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3161013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25637044 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25637044 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 22861074 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 2711992 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25816713 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20723985 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26787360 — Biomarker: PICALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PICALM; CALM
Study 21370966 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21370966 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21370966 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29878264 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 16150255 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 30955977 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 30955977 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 30955977 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 22035463 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17211296 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17211296 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 14651394 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 29800622 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 26691407 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12898820 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12898820 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21161116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17763203 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17763203 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17763203 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15199080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7659480 — Biomarker: Preexisting antibody
Type: Safety Biomarker (SAF)
Study 2396471 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study 93180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30138543 — Biomarker: GPRC6A mRNA
Type: Predictive Biomarker (PRD)
Genes: GPRC6A
Study 26969581 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 22463922 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 22463922 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22463922 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20934557 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30143003 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 18254326 — Biomarker: PARPBP mRNA
Type: Predictive Biomarker (PRD)
Genes: PARPBP; C12orf48; PARI
Study 31557061 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 31557061 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 31557061 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 31557061 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28004395 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 23486191 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23486191 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21857390 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 11120722 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11120722 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 4033356 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16166438 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 21716273 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 21716273 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9729054 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26272736 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 23884013 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 16137016 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 9225173 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16401468 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 15364856 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 10087435 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 23254482 — Biomarker: SRM mRNA
Type: Predictive Biomarker (PRD)
Genes: SRM; SPS1; SRML1
Study 16505657 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26385214 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21651805 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 16780624 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 8174528 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25322274 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20653352 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20653352 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18977721 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31514562 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31514562 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31514562 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 29616454 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29616454 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23550669 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 30856236 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24180595 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24180595 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 20444958 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15712083 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4