AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT03693196 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study NCT03693196 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study NCT01045421 — Biomarker: Aurora kinase A
Type: Predictive Biomarker (PRD)
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT02575612 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study NCT03421756 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT04027374 — Biomarker: FKBP5 mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: FKBP5; AIG6; FKBP51
Study NCT01229644 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT04118114 — Biomarker: PTP4A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTP4A3; PRL3
Study NCT03217409 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00086554 — Biomarker: ACAD8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAD8; ARC42; IBD
Study NCT03267420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02818387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00569413 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study NCT00772720 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT04653311 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study NCT03379012 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study NCT03065595 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT00965055 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00003743 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT03621007 — Biomarker: POMC mRNA
Type: Predictive Biomarker (PRD)
Genes: POMC
Study NCT03621007 — Biomarker: PCSK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK1; NEC1
Study NCT03664661 — Biomarker: TNFRSF17 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF17; BCM; BCMA
Study NCT03158493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04209335 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study NCT02462655 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study NCT02462655 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04715997 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT00081809 — Biomarker: TNFSF10 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF10; APO2L; TRAIL
Study NCT00750126 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study NCT04226235 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03342599 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01692314 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01625130 — Biomarker: Nuclear factor erythroid 2-related factor 2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: NFE2L2; NRF2
Study NCT02466789 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study NCT02562482 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT02252653 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study NCT02030314 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02999282 — Biomarker: GRN mRNA
Type: Predictive Biomarker (PRD)
Genes: GRN
Study NCT03993964 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study NCT03993964 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01904006 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT04126213 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT02151721 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02151721 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03720340 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study NCT03433755 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04293549 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study NCT03329079 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02599376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02516410 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study NCT02516410 — Biomarker: CFTR
Type: Predictive Biomarker (PRD)
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study NCT00996931 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01404871 — Biomarker: SLC1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC1A1; EAAC1; EAAT3; HEAAC1
Study NCT01404871 — Biomarker: GRIN2B mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIN2B; NMDAR2B
Study NCT01404871 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study NCT04594174 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03477656 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study NCT02939014 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study NCT02480218 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT02480218 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT00437463 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT00703508 — Biomarker: Serine/threonine-protein kinase STK11
Type: Safety Biomarker (SAF)
Genes: STK11
Study NCT02893995 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT04367805 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT02060409 — Biomarker: U2AF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: U2AF1; U2AF35; U2AFBP; FP793
Study NCT02060409 — Biomarker: ZRSR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZRSR2; U2AF1-RS2; U2AF1L2; U2AF1RS2; URP
Study NCT02596386 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study NCT00832221 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study NCT00829270 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT02896608 — Biomarker: HCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HCN1; BCNG1
Study NCT05017844 — Biomarker: KSR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KSR1; KSR
Study NCT00764634 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT03779646 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study NCT03779646 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT01940497 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03043560 — Biomarker: KCNQ2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNQ2
Study NCT00749281 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study NCT02987959 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study NCT01643512 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01294826 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT00430950 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01281761 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT01918631 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT02963402 — Biomarker: ENTPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ENTPD1; CD39
Study NCT02429037 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study NCT01049620 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study NCT01049620 — Biomarker: Hypoxia-inducible factor 1-alpha
Type: Predictive Biomarker (PRD)
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study NCT03937349 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study NCT03937349 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study NCT06451393 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study NCT04546893 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT04069546 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT03642353 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT06196021 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT04729647 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT04729647 — Biomarker: Platelet to lymphocyte
Type: Safety Biomarker (SAF)
Study NCT04254835 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study NCT02598258 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00398931 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01092078 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02276079 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT02276079 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT03863483 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02396784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01828944 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01717430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01566864 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03332797 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT03332797 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03332797 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT03061955 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02011750 — Biomarker: TOX mRNA
Type: Predictive Biomarker (PRD)
Genes: TOX; KIAA0808
Study NCT02011750 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study NCT02011750 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study NCT03795831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04019184 — Biomarker: IGFBP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP7; MAC25; PSF
Study NCT03864042 — Biomarker: ABCG2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT03864042 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study NCT03084237 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03508687 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study NCT02867657 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02357342 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT02225665 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study NCT00831636 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study NCT03733873 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study NCT01304693 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT03648034 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03648034 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT00865514 — Biomarker: GSTZ1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTZ1; MAAI
Study NCT02824471 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02593513 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT03766490 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00356980 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01259115 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT03335852 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03335852 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT03201406 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT00116519 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study NCT00116519 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT01700426 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03427879 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study NCT03427879 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03427879 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT03427879 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study NCT03045289 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study NCT04387682 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study NCT04387682 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study NCT01393184 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03618472 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study NCT01491230 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT03353454 — Biomarker: ATP8B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATP8B1; ATPIC; FIC1; PFIC
Study NCT03277209 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study NCT03624803 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT02083237 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02290275 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01850095 — Biomarker: TLR2
Type: Predictive Biomarker (PRD)
Genes: TIL4; CD282
Study NCT03525730 — Biomarker: BANF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BANF1; BAF; BCRG1
Study NCT00459485 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00700414 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study NCT00773695 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00953108 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study NCT04854252 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01879176 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02918409 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT00621036 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT02546349 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study NCT02546349 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT02546349 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT04394871 — Biomarker: SETX mRNA
Type: Predictive Biomarker (PRD)
Genes: SETX; ALS4; KIAA0625; SCAR1
Study NCT02635581 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00747214 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00826579 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study NCT04070339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00355472 — Biomarker: CCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR4; CMKBR4
Study NCT00062166 — Biomarker: VHL mRNA
Type: Predictive Biomarker (PRD)
Genes: VHL
Study NCT00059787 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01805726 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04322149 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study NCT03762499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00673933 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study NCT00012467 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT01631513 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study NCT05862194 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04679272 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT02027935 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study NCT02027935 — Biomarker: CTLA4
Type: Predictive Biomarker (PRD)
Genes: CD152; CD; GSE; CTLA-4
Study NCT01710436 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT04097171 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02899949 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00976794 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01933594 — Biomarker: Histone acetylation
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01319786 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00262119 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study NCT01157897 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study NCT00429520 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT04542850 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT01782508 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study NCT03916523 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03324321 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04078438 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT04078438 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT04026685 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01524913 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT01347866 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study NCT01347866 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT01508754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02217150 — Biomarker: STAR mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAR; STARD1
Study NCT00668200 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study NCT01401257 — Biomarker: Peripheral myelin protein 22
Type: Pharmacodynamic Biomarker (PDY)
Genes: PMP22; GAS3
Study NCT03981549 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT00196131 — Biomarker: PGP mRNA
Type: Predictive Biomarker (PRD)
Genes: PGP
Study NCT01764295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00290394 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study NCT00290394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03326674 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03326674 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT02218112 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01036490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00173537 — Biomarker: BMPR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BMPR2; PPH1
Study NCT02467582 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study NCT01741779 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03117036 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study NCT01772381 — Biomarker: TTN mRNA
Type: Predictive Biomarker (PRD)
Genes: TTN
Study NCT01235702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01565265 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT00181220 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study NCT05149339 — Biomarker: ADAMTS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT05149339 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT05149339 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT03663387 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01941940 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT02993692 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04455178 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04094376 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM