AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 21955862 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 9055135 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9055135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8417172 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8417172 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 15483282 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 29126416 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 12830440 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 12830440 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2499466 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 2499466 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 28051240 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24579084 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 24579084 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 24579084 — Biomarker: PDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PDK4; PDHK4
Study 24579084 — Biomarker: FADS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS1; FADSD5
Study 22718792 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15837236 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 28894292 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 28894292 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 28894292 — Biomarker: CPT1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CPT1A; CPT1
Study 28894292 — Biomarker: UCP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP2; SLC25A8
Study 28894292 — Biomarker: UCP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP1; SLC25A7; UCP
Study 16280286 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7604803 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8179847 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8179847 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 20818194 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3928213 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 29136001 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21552185 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21552185 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 21552185 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 23900047 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 16623404 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1314871 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24104542 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18004127 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14712422 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26404199 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 23722481 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2679084 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2679084 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31937617 — Biomarker: TK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TK1
Study 31937617 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 31937617 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26254792 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 12767425 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 9425505 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9301631 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 30257125 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26562003 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25267153 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22332874 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22332874 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 22332874 — Biomarker: STIM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STIM1; GOK
Study 22332874 — Biomarker: PTPN22 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPN22; PTPN8
Study 20504126 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10351973 — Biomarker: RHD mRNA
Type: Predictive Biomarker (PRD)
Genes: RHD
Study 10351973 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 6414271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25658497 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 25658497 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 24356339 — Biomarker: APEX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 24356339 — Biomarker: OGG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OGG1; MMH; MUTM; OGH1
Study 24356339 — Biomarker: MPG mRNA
Type: Predictive Biomarker (PRD)
Genes: MPG; AAG; ANPG; MID1
Study 21919922 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30069238 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25557266 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23852947 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12578874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26758251 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 26758251 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24652053 — Biomarker: DIS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DIS3; KIAA1008; RRP44
Study 12140806 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30007333 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 26729950 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26729950 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21849651 — Biomarker: T-cell specific protein RANTES
Type: Safety Biomarker (SAF)
Genes: CCL5; D17S136E; SCYA5
Study 21849651 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 21849651 — Biomarker: Small-inducible cytokine A11
Type: Predictive Biomarker (PRD)
Genes: CCL11; SCYA11
Study 26431906 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 26618505 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 22124576 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21419314 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29808316 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 22961097 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 22961097 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 11553182 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9757854 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8151606 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2470358 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12386042 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2309645 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 2309645 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27545497 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 27545497 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22168961 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 22168961 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11748333 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7547078 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23645690 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 10813541 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 26198842 — Biomarker: Urokinase plasminogen activator surface receptor
Type: Monitoring Biomarker (MOI)
Genes: PLAUR; MO3; UPAR
Study 23599045 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 16467415 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8557151 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 30027607 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30027607 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9270086 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9270086 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12970289 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12970289 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 10656170 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10656170 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10656170 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 8683863 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 4013351 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4013351 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22733474 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22733474 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19949016 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15867200 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30451307 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 30451307 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11838000 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 27928704 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25646817 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17378918 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 11413083 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 8111502 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29951651 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29951651 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3737785 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 26785220 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 11133320 — Biomarker: STAR mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAR; STARD1
Study 10168532 — Biomarker: Nasal potential difference
Type: Pharmacodynamic Biomarker (PDY)
Study 2884723 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 26268815 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 16628063 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 16628063 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22030715 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 8847943 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8847943 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30277014 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 1589701 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1589701 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3897071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29573567 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 17700397 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15868595 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 11998815 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 2755214 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 15120888 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15120888 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9706829 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25671796 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3307093 — Biomarker: Plasma testosterone level
Type: Surrogate Endpoint (SUR)
Study 30572894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30572894 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 21905086 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 12552952 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 12552952 — Biomarker: TYMS
Type: Predictive Biomarker (PRD)
Genes: Tsase; TMS; HsT422
Study 7815748 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2576666 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23788085 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 15333056 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8670601 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1662583 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31912800 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 31912800 — Biomarker: HRG mRNA
Type: Predictive Biomarker (PRD)
Genes: HRG
Study 14984149 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 14728013 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14728013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3119959 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 3119959 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 2869057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22117974 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 2691819 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2691819 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 2691819 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4581080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30586365 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 30586365 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 27586506 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 27586506 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 27586506 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 19025397 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 19025397 — Biomarker: KLRC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRC1; NKG2A
Study 19025397 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19025397 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 25746819 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10216104 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 10216104 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12920491 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 12920491 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 12920491 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 3701184 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24309381 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 15693916 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7672685 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31563397 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31399108 — Biomarker: NOX4 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOX4; RENOX
Study 31399108 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 17436778 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17436778 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9496204 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9496204 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 7934984 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24991038 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 10862645 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10862645 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 9357886 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 15001601 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10546469 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7075639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31876118 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26909743 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23379240 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 20702792 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16242948 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 11855542 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11855542 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 22648712 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 16318978 — Biomarker: PIBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PIBF1; C13orf24; PIBF
Study 12629248 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 12569789 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12569789 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 1992214 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1992214 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29656442 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 29656442 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 29656442 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 17613258 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 6154200 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28389510 — Biomarker: SLCO2B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 24518789 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 11606148 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2189430 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 1106218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27935076 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 19273450 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 19273450 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16893569 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 11397886 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 17943257 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12787302 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 12787302 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 12787302 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 12787302 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12787302 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 8723581 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 30814213 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP