AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24432669 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17166358 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8214944 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 31115739 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31880807 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 17163237 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30496705 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 28760225 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 28760225 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28760225 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20524999 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17768587 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16624969 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 30387335 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30387335 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30387335 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30387335 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27339806 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24365797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8534464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28479118 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 28479118 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 21258206 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21258206 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 7879322 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 20002082 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 16804951 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10807761 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10807761 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18584266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 795441 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 12715722 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 29795141 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12214263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8527266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25926562 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 6234335 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1686250 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 1686250 — Biomarker: PTK7 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTK7; CCK4
Study 30453889 — Biomarker: MEST mRNA
Type: Predictive Biomarker (PRD)
Genes: MEST; PEG1
Study 18317375 — Biomarker: DDIT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT4; REDD1; RTP801
Study 18317375 — Biomarker: Hypoxia-inducible factor 1-alpha
Type: Predictive Biomarker (PRD)
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 18317375 — Biomarker: TRIM63 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 18317375 — Biomarker: MSTN mRNA
Type: Predictive Biomarker (PRD)
Genes: MSTN; GDF8
Study 10862158 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9322569 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18781853 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 16755268 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15307693 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 15307693 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15307693 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 15307693 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 3080693 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 27133819 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 22064737 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 8458057 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8458057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2957124 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 23801158 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21807330 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19027814 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 9476456 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9476456 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 3584738 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10690940 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 10690940 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7662242 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31929469 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 17140398 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16297751 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16297751 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 16297751 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 16297751 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9719019 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7078717 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 31641767 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26051874 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 16714852 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27490921 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20199367 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12847071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11783243 — Biomarker: DSP mRNA
Type: Predictive Biomarker (PRD)
Genes: DSP
Study 25414593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14522414 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 14522414 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 14522414 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 14522414 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1623802 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30007061 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 19450896 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 19450896 — Biomarker: CXCR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR3; GPR9
Study 12228789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27010995 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 3658285 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3658285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27484224 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22494852 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21168619 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11040177 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15753149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11728984 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27166718 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 16624686 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 16624686 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14661009 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2124180 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 6153846 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27503905 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study 27503905 — Biomarker: GLS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS2; GA
Study 7837215 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7837215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30738706 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 26431662 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23422375 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20700581 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15155117 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12414877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12414877 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28675067 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 24844580 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 22019520 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 22019520 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8326288 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2661065 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23322818 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19084935 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 16404492 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11244343 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 9256118 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 12848770 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 10574604 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 10574604 — Biomarker: MDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM2
Study 10574604 — Biomarker: Retinoblastoma-associated protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: RB1
Study 19855926 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17984108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12542609 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 25038314 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25038314 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 22422386 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21146749 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 17605023 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11522879 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11522879 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 9565804 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 10917002 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10917002 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 30819098 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29931092 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 24125844 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 24125844 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 24125844 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 8141692 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31889148 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29275580 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29275580 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23274145 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28446644 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 2426514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28513852 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26701110 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9065248 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27977472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20651608 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11162695 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 12164876 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 9205027 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11989838 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 10521743 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20574649 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15883634 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 12379164 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31821750 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 31196032 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 25719991 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12780746 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9354348 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9354348 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 9354348 — Biomarker: PRCP mRNA
Type: Predictive Biomarker (PRD)
Genes: PRCP; PCP
Study 8222508 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8222508 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8222508 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 27858150 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15811048 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 1714950 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 28423301 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 21114607 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14970135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16848777 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 11422727 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 15811704 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 31037288 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28158243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23681294 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 11742271 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 11742271 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 26137702 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18242128 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18242128 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12708605 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 1731547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9278828 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 27982198 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12796760 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24591201 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 1815225 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 27025186 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24696091 — Biomarker: ENTPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ENTPD1; CD39
Study 24696091 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 24696091 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 27295811 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27295811 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17498388 — Biomarker: SNAP25 mRNA
Type: Predictive Biomarker (PRD)
Genes: SNAP25; SNAP
Study 9717676 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 905483 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 9130130 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 7910028 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22695506 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 22695506 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31564585 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 21333698 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17602156 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17602156 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 17602156 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31868699 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 28179351 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 23783025 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 23795576 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6306711 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30608440 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 7654944 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 23040887 — Biomarker: FIP1L1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FIP1L1; FIP1; RHE
Study 23040887 — Biomarker: PDGFRA mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 11423497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8388332 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 8388332 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8388332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3812308 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30641827 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23780458 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8768852 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1993796 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16467018 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26633806 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26633806 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 21377179 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21377179 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21377179 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10761802 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 2671502 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20606150 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20606150 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29528692 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB