AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23566344 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 21746979 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 9205633 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9205633 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 25894960 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 25191599 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25191599 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9401829 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28714771 — Biomarker: Argininosuccinate synthase
Type: Safety Biomarker (SAF)
Genes: ASS1; ASS
Study 11985407 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15307698 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12531809 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 21796128 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21796128 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 21796128 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19587440 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15290731 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12612946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12612946 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30909690 — Biomarker: ALDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH2; ALDM
Study 22817122 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22817122 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 20136474 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 9784666 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 26649464 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 17403704 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 16422873 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 10411372 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7572595 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10573065 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 2032147 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2032147 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 2032147 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 2032147 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8955759 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 1597983 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 11910310 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11910310 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11910310 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9426828 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 2643892 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 31998472 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 21406601 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21406601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17890444 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 15042130 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7025500 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19820906 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 11914251 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9210501 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9210501 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3621278 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 31958932 — Biomarker: ACRC mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNA; ACRC
Study 24368613 — Biomarker: FBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBP1; FBP
Study 10095804 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21314449 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19843669 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 19843669 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 11734734 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 25394242 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 25394242 — Biomarker: S100A12 mRNA
Type: Predictive Biomarker (PRD)
Genes: S100A12
Study 25394242 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7753538 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27471208 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9952145 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6777812 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 26951309 — Biomarker: VHL mRNA
Type: Predictive Biomarker (PRD)
Genes: VHL
Study 17219171 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24748593 — Biomarker: NANOS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS3; NOS3
Study 24748593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10647066 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9296311 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9296311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20485957 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26771340 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17328070 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18497598 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 17174704 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22128042 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19150743 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12153554 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7543891 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 322922 — Biomarker: NAPA mRNA
Type: Predictive Biomarker (PRD)
Genes: NAPA; SNAPA
Study 23829604 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 17196507 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12127031 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 2752698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2752698 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 20976802 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 20976802 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 20976802 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 402831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24866348 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19821717 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8346819 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3518912 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 31740106 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 26584035 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 18182447 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 16687344 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11024215 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9236507 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8384096 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8384096 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30296325 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26412463 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15795184 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8507448 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31714470 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30283014 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 30283014 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 1898694 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1898694 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21550556 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 11244189 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2503114 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31918452 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 18813917 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 10698387 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9412257 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31562799 — Biomarker: Homologous recombination deficiency
Type: Predictive Biomarker (PRD)
Study 11156644 — Biomarker: ID1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ID1; BHLHB24; ID
Study 15501704 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27648674 — Biomarker: MMD mRNA
Type: Predictive Biomarker (PRD)
Genes: MMD; PAQR11
Study 20091404 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10904461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9291340 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9291340 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7686709 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7686709 — Biomarker: Interleukin 1 alpha
Type: Safety Biomarker (SAF)
Genes: IL1A; IL1F1
Study 30583933 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25382740 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 27737534 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 22688605 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 22688605 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21777715 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 4096071 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 31737686 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 29929990 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26966825 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17618954 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11023477 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8228207 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8228207 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3521858 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31067190 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17191734 — Biomarker: FGG mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGG; PRO2061
Study 22307477 — Biomarker: ADH1C mRNA
Type: Predictive Biomarker (PRD)
Genes: ADH1C; ADH3
Study 24033696 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 24033696 — Biomarker: CHRNA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA5; NACHRA5
Study 20234305 — Biomarker: CPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPB1; CPB; PCPB
Study 324257 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8936955 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 28679529 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study 28679529 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 26545535 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31798891 — Biomarker: Angiopoietin-related protein 4
Type: Predictive Biomarker (PRD)
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 31798891 — Biomarker: DAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DAPK3; ZIPK
Study 31798891 — Biomarker: PER1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PER1; KIAA0482; PER; RIGUI
Study 31798891 — Biomarker: TNFAIP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFAIP3; OTUD7C
Study 18622250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9892589 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31658543 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31658543 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 31658543 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 15472191 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 15472191 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 15472191 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29652246 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29652246 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23949961 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 23949961 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 8894914 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1503282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29233588 — Biomarker: miR-99b
Type: Monitoring Biomarker (MOI)
Genes: MIR99B
Study 29233588 — Biomarker: miR-423
Type: Safety Biomarker (SAF)
Genes: MIR423
Study 29233588 — Biomarker: let-7c
Type: Predictive Biomarker (PRD)
Genes: MIRLET7C
Study 30344165 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 27770771 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 46951 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1832701 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1832701 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6227208 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31527690 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31527690 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31527690 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21853290 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 21853290 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 11877767 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 21926656 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17379842 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 415471 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 27696656 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 27696656 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 25680375 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 19387331 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 9636912 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9636912 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 7872715 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 26301701 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 29596158 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 22648092 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22648092 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12551863 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31933439 — Biomarker: C6orf15 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6orf15; STG; UNQ1840/PRO3566
Study 24997757 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 15089890 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 22013105 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22013105 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 22013105 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 22013105 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 23382325 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15614026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11724449 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2462444 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15696321 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25536308 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25536308 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24565455 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 24590363 — Biomarker: Major prion protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRNP; ALTPRP; PRIP; PRP
Study 1932647 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16774821 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12730756 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21795429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21795429 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 29277297 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study 29277297 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 23585468 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 23585468 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 20573223 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 8970247 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1468826 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29034453 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 23193843 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18396107 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15573384 — Biomarker: ST8SIA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ST8SIA4; PST; PST1; SIAT8D
Study 12008175 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3565526 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 23609777 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 29389068 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 26560898 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26560898 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 15733508 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 2223528 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17313720 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1