AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 17049693 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12771518 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 22748591 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 22748591 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16683408 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10988282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21850574 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12857474 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12857474 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 6748924 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 30650322 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 30304106 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 30304106 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 30304106 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26935578 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 17409312 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15365746 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 15365746 — Biomarker: BAX mRNA
Type: Predictive Biomarker (PRD)
Genes: BAX; BCL2L4
Study 15365746 — Biomarker: BAD mRNA
Type: Predictive Biomarker (PRD)
Genes: BAD; BBC6; BCL2L8
Study 9756423 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29649631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16503543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10638374 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 30288918 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 25880054 — Biomarker: FABP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FABP4
Study 19850207 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19850207 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28424185 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 28424185 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 28424185 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7614505 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 983179 — Biomarker: EMB mRNA
Type: Predictive Biomarker (PRD)
Genes: EMB
Study 29311704 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23418955 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19967620 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 15181054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12085979 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7866911 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 7866911 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 22220945 — Biomarker: DMTN mRNA
Type: Predictive Biomarker (PRD)
Genes: DMTN; DMT; EPB49
Study 10049274 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7577484 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 24634622 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24634622 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 24634622 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24634622 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24634622 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 21952002 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12060421 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 29609921 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23393217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22815422 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15977870 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23946220 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 23946220 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23946220 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23946220 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23946220 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 16874005 — Biomarker: HTR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2A; HTR2
Study 16874005 — Biomarker: HTR3A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR3A; 5HT3R; HTR3
Study 15257469 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 15257469 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 9407327 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8516523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3044238 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7873457 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 1445483 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 26759167 — Biomarker: MCCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCCC2; MCCB
Study 24626147 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 22007690 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22007690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20214496 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11464257 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9681128 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9681128 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26063890 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21558577 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 31382292 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24168756 — Biomarker: CD83 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD83
Study 24168756 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 8881869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10444434 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 7483181 — Biomarker: CALD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CALD1; CAD; CDM
Study 27229348 — Biomarker: MT2A mRNA
Type: Predictive Biomarker (PRD)
Genes: MT2A; CES1; MT2
Study 20499349 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11011338 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 8803378 — Biomarker: SRM mRNA
Type: Predictive Biomarker (PRD)
Genes: SRM; SPS1; SRML1
Study 28506134 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20651609 — Biomarker: SLC19A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC19A1; FLOT1; RFC1
Study 20651609 — Biomarker: GGH mRNA
Type: Predictive Biomarker (PRD)
Genes: GGH
Study 16305652 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19925284 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19925284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25026506 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 31925529 — Biomarker: TRIM63 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 16500921 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11396393 — Biomarker: RAF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAF1; RAF
Study 28755607 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 28755607 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20827547 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 870096 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31500605 — Biomarker: PAICS mRNA
Type: Predictive Biomarker (PRD)
Genes: PAICS; ADE2; AIRC; PAIS
Study 31500605 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 31500605 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 26952317 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 12231595 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7864425 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7864425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20857093 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 20857093 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 24692816 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16793604 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16793604 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16793604 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 9143790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30732506 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28651370 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 27737719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22007645 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15080375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31662352 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 31662352 — Biomarker: CES2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CES2; ICE
Study 29156912 — Biomarker: NBPF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NBPF1; KIAA1693
Study 29156912 — Biomarker: DNM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DNM2; DYN2
Study 29156912 — Biomarker: TSEN54 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSEN54; SEN54
Study 29156912 — Biomarker: DHODH mRNA
Type: Predictive Biomarker (PRD)
Genes: DHODH
Study 29156912 — Biomarker: UGT2A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: UGT2A1
Study 29156912 — Biomarker: VLDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: VLDLR
Study 29156912 — Biomarker: SEC23A mRNA
Type: Predictive Biomarker (PRD)
Genes: SEC23A
Study 29156912 — Biomarker: HAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HAS1; HAS
Study 29156912 — Biomarker: ADAMTS16 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAMTS16; KIAA2029
Study 12020142 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31778431 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 28351393 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28351393 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28351393 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11720199 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 22894624 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22894624 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12054161 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22042106 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 18450596 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 7762523 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 7762523 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25970149 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25970149 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25970149 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23439424 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 19101496 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9308762 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9308762 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28326681 — Biomarker: MAP2K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K1; MEK1; PRKMK1
Study 16649186 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 19793849 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20039197 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18772275 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23082447 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 17868242 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16868976 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12534315 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12534315 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12534315 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 10649617 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study 8783388 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 19584979 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19584979 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7004273 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 21382868 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 3259100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26583660 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 17319450 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17353316 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 28941607 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 26571421 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 26571421 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23416142 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 31754133 — Biomarker: PPP3R1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPP3R1; CNA2; CNB
Study 25145487 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17925486 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 30570938 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27090108 — Biomarker: DDT mRNA
Type: Predictive Biomarker (PRD)
Genes: DDT
Study 16503695 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 12948274 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18675744 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8410120 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 30786916 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 30786916 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 11930332 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9452835 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21251985 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 19117313 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15247553 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15247553 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3326634 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 16306217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28681171 — Biomarker: IGF1R mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1R
Study 28681171 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27188987 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 27188987 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26068323 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17705186 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31090170 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 30736781 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28499715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31051059 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31051059 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 29314138 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 11530400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23496876 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 21493747 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 12548082 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10911780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3891203 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 3891203 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24906587 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18479954 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 1951831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25527737 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 25527737 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 11762561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10322845 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10322845 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7679040 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 25761833 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25761833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18785569 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18785569 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 18785569 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 23980044 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19661049 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 19661049 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10340958 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22009916 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 19560695 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 19560695 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 16480759 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 31923642 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 27780932 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 27780932 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 27780932 — Biomarker: Platelet to lymphocyte
Type: Safety Biomarker (SAF)
Study 26419096 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)