AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 28222525 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 23505907 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16818281 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 29378998 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21205136 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 25908506 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25908506 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 25908506 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 16750455 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 7988251 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 24648723 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 24648723 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 18076246 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18076246 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8930940 — Biomarker: GCSAM mRNA
Type: Predictive Biomarker (PRD)
Genes: GCSAM; GAL; GCET2
Study 8930940 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 8930940 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8930940 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6132819 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19362675 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16339095 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7577781 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 2034479 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31907024 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 31907024 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 27266853 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20499072 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20499072 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 20499072 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16531164 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 16531164 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 3157576 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22503790 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 9253321 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29772657 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29772657 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 15727954 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11990404 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21174144 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19581353 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9256938 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9256938 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 31235428 — Biomarker: MGP mRNA
Type: Predictive Biomarker (PRD)
Genes: MGP; MGLAP; GIG36
Study 15077288 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12153607 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7082858 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 31398275 — Biomarker: HDAC8 mRNA
Type: Predictive Biomarker (PRD)
Genes: HDAC8; HDACL1; CDA07
Study 29464691 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 29464691 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24628390 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20555373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3570421 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24318038 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21374068 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18979504 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18979504 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18979504 — Biomarker: PLIN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLIN2; ADFP
Study 18979504 — Biomarker: Vascular endothelial cadherin
Type: Safety Biomarker (SAF)
Genes: CDH5
Study 18979504 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 18979504 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 14738235 — Biomarker: TAC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAC1; NKA; NKNA; TAC2
Study 9661678 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 7923825 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2894902 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28375559 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 15863522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31561715 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 28375792 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 28375792 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 28551092 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 21841500 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19123865 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7972620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28915907 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23051870 — Biomarker: NELFCD mRNA
Type: Predictive Biomarker (PRD)
Genes: NELFCD; NELFD; TH1; TH1L; HSPC130
Study 23051870 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 17674017 — Biomarker: KCNH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNH2; ERG; ERG1; HERG
Study 16549931 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12759270 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 8500312 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 30970404 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 30970404 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 30970404 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 27696203 — Biomarker: ELN mRNA
Type: Predictive Biomarker (PRD)
Genes: ELN
Study 19155235 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19155235 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18071724 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 1974677 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31927126 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 31927126 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22083332 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 15986873 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31996543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9447854 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9447854 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 348378 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11860403 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 619938 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 12448067 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12448067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19910654 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15151941 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 22934396 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12466165 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30784354 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 30784354 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 28213565 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28213565 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22475140 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 7968423 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7968423 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15119922 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 11231440 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 11231440 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8176138 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 4400530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31371154 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 30712955 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 28369078 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 28369078 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 28369078 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 23704939 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 23704939 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 16440917 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7484285 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 7484285 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18321680 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 18321680 — Biomarker: C6orf15 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6orf15; STG; UNQ1840/PRO3566
Study 18321680 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 14585761 — Biomarker: LIPC mRNA
Type: Predictive Biomarker (PRD)
Genes: LIPC; HTGL
Study 1457788 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2127335 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31006038 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 1758944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24480430 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24480430 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 20807120 — Biomarker: DMRT1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DMRT1; DMT1
Study 15768872 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12191719 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 7797216 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3134082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22420471 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12351435 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12351435 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 31464626 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12040670 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 12568173 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7553996 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7553996 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27150635 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 27150635 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 10207807 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 7599914 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2221406 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23807528 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22046394 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16476841 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 12771010 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10677157 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 10677157 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 10619727 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28077140 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26025128 — Biomarker: TBCD mRNA
Type: Predictive Biomarker (PRD)
Genes: TBCD; KIAA0988; SSD1; TFCD; PP1096
Study 21225278 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 21225278 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21225278 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 7987084 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 31366355 — Biomarker: CDS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDS1; CDS
Study 2864845 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22967772 — Biomarker: ANKK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANKK1; PKK2; SGK288
Study 22967772 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 22967772 — Biomarker: HTR2C mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2C; HTR1C
Study 22967772 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 2200924 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2200924 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31759092 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31759092 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8457524 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 3721646 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 30138966 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 30138966 — Biomarker: Insulin receptor substrate 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IRS1
Study 19292064 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3511392 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29982277 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 11130159 — Biomarker: DDX53 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDX53; CAGE
Study 27041672 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 27041672 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27041672 — Biomarker: ALDH1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH1A1; ALDC; ALDH1; PUMB1
Study 8106625 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 19663128 — Biomarker: VIT mRNA
Type: Predictive Biomarker (PRD)
Genes: VIT; UNQ647/PRO1277
Study 2671617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2671617 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 23287638 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 23287638 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 7639365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30674430 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 23415313 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 21154196 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 2859871 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27626473 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27592520 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23917748 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 23917748 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 8360391 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 2875439 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15562020 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 1695049 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 31209192 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 23786282 — Biomarker: ZAP70 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZAP70; SRK
Study 23786282 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 9272403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24502842 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 22172428 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20420510 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25416193 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16718629 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15337695 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19487269 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19487269 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 19487269 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 19487269 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 19487269 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 1425726 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3907843 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8809640 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27684533 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27684533 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23644651 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 20663996 — Biomarker: ABL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABL2; ABLL; ARG
Study 12515162 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12515162 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 2543553 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16918513 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 15307010 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11795863 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8431665 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8431665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24225740 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 18709511 — Biomarker: LARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LARS1; KIAA1352; LARS
Study 8636748 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3