AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 11920412 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31164429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20107424 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12126174 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 26489022 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 26489022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24480677 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24480677 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21761705 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 25801872 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14671251 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14671251 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 14671251 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14671251 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 11704025 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 11704025 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2467139 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12472790 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 10716688 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 29512481 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 22723310 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9730792 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 7518981 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7518981 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21355157 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 11896626 — Biomarker: CCND1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND1; BCL1; PRAD1
Study 11896626 — Biomarker: Epithelial cadherin
Type: Predictive Biomarker (PRD)
Genes: CDH1; CDHE; UVO
Study 11896626 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 90215 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 23289548 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 14703595 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1832516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7046331 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24315572 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 20142023 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 20142023 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 20142023 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 18388356 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 2454359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17101625 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11889149 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9462526 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 22374183 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 12670837 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 9139272 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 29907211 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26917157 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 18418433 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10782623 — Biomarker: PHEX mRNA
Type: Predictive Biomarker (PRD)
Genes: PHEX; PEX
Study 8877661 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 31325499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31325499 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 25631734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1885274 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11334210 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28345814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26041602 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26310670 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 23850610 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31131671 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 31131671 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 31131671 — Biomarker: RANGAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RANGAP1; KIAA1835; SD
Study 31131671 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 31131671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11982838 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28822563 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 21372264 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30922878 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24641328 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 20118387 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20118387 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7898092 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7898092 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14615726 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10771453 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 30006015 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 17711511 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10790350 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 11317490 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8615360 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30616442 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 20863994 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 20863994 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 20863994 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 15998659 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 15998659 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 15998659 — Biomarker: TCHH mRNA
Type: Predictive Biomarker (PRD)
Genes: TCHH; THH; THL; TRHY
Study 30934066 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 9345396 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9345396 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 22263337 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 15015442 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 22451470 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22451470 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18828769 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 18828769 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 18828769 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 18828769 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18828769 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 18828769 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 18828769 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 16583932 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 22465268 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6358654 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31930897 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20012296 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 20012296 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 10365639 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 31913428 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 26689589 — Biomarker: APLP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APLP1
Study 10867091 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9772413 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9772413 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8246027 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 31450983 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 16995870 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 3276185 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3276185 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3276185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31372823 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31372823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26439700 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 14551526 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29433963 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29433963 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 1672967 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6130595 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19473807 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10915751 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 28429577 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24030130 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17461873 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6796322 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23484369 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 18579230 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7920892 — Biomarker: IHH mRNA
Type: Predictive Biomarker (PRD)
Genes: IHH
Study 7537110 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7537110 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7049582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26684265 — Biomarker: ASPSCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 25351765 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 11181655 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 16564254 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16564254 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14602763 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14602763 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8775350 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8775350 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31905348 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 28695815 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23223867 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 23223867 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 19382426 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16906286 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 27163986 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 30102872 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23972276 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19474134 — Biomarker: CFLAR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFLAR; CASH; CASP8AP1; CLARP; MRIT
Study 29381374 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 28277490 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 26590242 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20092961 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 20092961 — Biomarker: MDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM2
Study 14521760 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 31574029 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 26705327 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 18050245 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 7671564 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 27417920 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11443192 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11443192 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11443192 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11443192 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11443192 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 8033141 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8033141 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 8033141 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 21524316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16573163 — Biomarker: PTK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTK2; FAK; FAK1
Study 29606109 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 29606109 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 29606109 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 29606109 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 29606109 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 24191305 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 24191305 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24191305 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24191305 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22301410 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22301410 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 22301410 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8583467 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24739759 — Biomarker: LY75 mRNA
Type: Predictive Biomarker (PRD)
Genes: LY75; CD205; CLEC13B
Study 24739759 — Biomarker: TLR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR7; UNQ248/PRO285
Study 24739759 — Biomarker: TLR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR3
Study 19065903 — Biomarker: PAG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAG1; CBP; PAG
Study 10892945 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 1329478 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1329478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3864225 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29860922 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 29860922 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 19660268 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 7590390 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 7590390 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23743803 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 23743803 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23743803 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23743803 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20426759 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20426759 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 26559637 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 24496699 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19103535 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19103535 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 19103535 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31774468 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 16676791 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 27636922 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17950857 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 17950857 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 16258094 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 12079437 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12079437 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8062153 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8062153 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25641537 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24154787 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 22707609 — Biomarker: Preexisting antibody
Type: Safety Biomarker (SAF)
Study 9013103 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9013103 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 9013103 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 9013103 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9013103 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 21269578 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19713451 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16042672 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7840686 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3122698 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 22834968 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10556990 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 10556990 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8753945 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 1861487 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31689513 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26493094 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105