AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 7028356 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25105367 — Biomarker: FCGR2C mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR2C; CD32; FCG2; IGFR2
Study 22299661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22940056 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 22940056 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17047615 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17047615 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17047615 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3578255 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 19394473 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16567606 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8442970 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29943702 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22495111 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10228814 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 18596958 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12412676 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 10357919 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 29466592 — Biomarker: HLF mRNA
Type: Predictive Biomarker (PRD)
Genes: HLF
Study 27197287 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 27197287 — Biomarker: SOD2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SOD2
Study 27197287 — Biomarker: SOD3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOD3
Study 27197287 — Biomarker: TXNRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TXNRD2; KIAA1652; TRXR2
Study 27197287 — Biomarker: SEC14L2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEC14L2; C22orf6; KIAA1186; KIAA1658
Study 16376753 — Biomarker: MXD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MXD1; MAD
Study 23690338 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23690338 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 8213508 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29723592 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29723592 — Biomarker: AIP mRNA
Type: Predictive Biomarker (PRD)
Genes: AIP; XAP2
Study 29723592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29723592 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29723592 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18959679 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 10720167 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10720167 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10720167 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1380197 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1380197 — Biomarker: Alpha-1-acid glycoprotein 1
Type: Monitoring Biomarker (MOI)
Genes: ORM1; AGP1
Study 25550337 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8789469 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8789469 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 383195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31754697 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 31152327 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31152327 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31152327 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 2688602 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 2688602 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2688602 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 25798680 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 11343441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27774892 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26442402 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26442402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16357312 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 16357312 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16357312 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16357312 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9066316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28284202 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21807618 — Biomarker: NANOS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS3; NOS3
Study 17005501 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8370370 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30175329 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30175329 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 8730004 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8730004 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 21036667 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21036667 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 8564625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31669427 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27829371 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20373477 — Biomarker: INSIG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: INSIG2
Study 1282465 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 21248294 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 21248294 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 6117516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26647424 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 26647424 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 26647424 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25701373 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 12610022 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12610022 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28384735 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25918454 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 25918454 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 21836044 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 10968496 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 9280188 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8315953 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8315953 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27429618 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 15326131 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 27815511 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 25837219 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9753527 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 16331635 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 14616412 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 14616412 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 14616412 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 19008099 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 19008099 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19008099 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 19008099 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15081441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15081441 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 28609330 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17263930 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2200253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15837247 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 11844743 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10357325 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31658058 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 24211751 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14734002 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 18191071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18191071 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17190179 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1573032 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27020669 — Biomarker: SGK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SGK1; SGK
Study 19832854 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10332129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1763923 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30186817 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 28954926 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11601117 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11601117 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7740450 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 28485320 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15222407 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9218208 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2952213 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 26253453 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 26253453 — Biomarker: BAX mRNA
Type: Predictive Biomarker (PRD)
Genes: BAX; BCL2L4
Study 26253453 — Biomarker: miR-1
Type: Safety Biomarker (SAF)
Study 26253453 — Biomarker: miR-21
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR21
Study 23897769 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22739373 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 16046950 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30796855 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 28489856 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25582225 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 19628651 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16358341 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 16358341 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10822123 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27173369 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14588450 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 30107283 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 29943364 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21372694 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17970056 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 11340346 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9701103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18793245 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 27577177 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27577177 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 15033400 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11793859 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 11793859 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25917434 — Biomarker: TNFRSF9 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF9; CD137; ILA
Study 16492219 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10880416 — Biomarker: SCARA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SCARA3; CSR
Study 11890650 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7930736 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7930736 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3283292 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24326529 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 19074207 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28815689 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27264224 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 27264224 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22948196 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21191426 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9856967 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2744779 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20977840 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20977840 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8466735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31356456 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 16159869 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 9585718 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8142644 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 21697704 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2579902 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2579902 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31171508 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 31171508 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 19576090 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 9578186 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 10610011 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1725026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1725026 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18084949 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23949882 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 12800099 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22038992 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 20337621 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20337621 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 20337621 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 20337621 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 18407904 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10071426 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 12836712 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23544125 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 23544125 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18194486 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18194486 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18194486 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 18194486 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18194486 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14615636 — Biomarker: GCA mRNA
Type: Predictive Biomarker (PRD)
Genes: GCA; GCL
Study 10636509 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10636509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10636509 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30710614 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 20357251 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11260566 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 23497371 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16965776 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 16965776 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 16965776 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30287050 — Biomarker: FABP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FABP4
Study 25833816 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25833816 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23924233 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 23924233 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9542480 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28380495 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19901194 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20721962 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15625254 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17072741 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16420253 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16420253 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27508319 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 27508319 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21685814 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11691649 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 22314136 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25552403 — Biomarker: SLC22A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A2; OCT2
Study 25552403 — Biomarker: SLC47A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC47A1; MATE1
Study 25552403 — Biomarker: SLC47A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC47A2; MATE2
Study 17942872 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 30451329 — Biomarker: S100A12 mRNA
Type: Predictive Biomarker (PRD)
Genes: S100A12
Study 30451329 — Biomarker: CST5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CST5
Study 30451329 — Biomarker: CD6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD6
Study 29891957 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 25190744 — Biomarker: SLC9A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC9A1; APNH1; NHE1
Study 25190744 — Biomarker: SLC16A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC16A4; MCT4; MCT5
Study 16765148 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 9014483 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31535628 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 28803380 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)