AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 11772951 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 11772951 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 19968402 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 19968402 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 2990189 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 25378675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10450748 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31082790 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23511339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20834026 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 20834026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20834026 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20834026 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20834026 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11208825 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 21524156 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18478022 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study 15339608 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 1533588 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1533588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1533588 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25732215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18441389 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 24417584 — Biomarker: RIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RIT1; RIBB; RIT; ROC1
Study 20206078 — Biomarker: ERCC8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC8; CKN1; CSA
Study 16812979 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11730274 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 18774947 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21429413 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8076659 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1613673 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 15446673 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9065721 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 7386234 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28777385 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 3909759 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29385062 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 29385062 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29385062 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29385062 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 20184866 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2405789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30467342 — Biomarker: CRHR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CRHR1; CRFR; CRFR1; CRHR
Study 26831124 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26831124 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22251408 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22251408 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 22251408 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 17951021 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 7986334 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 28196533 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 15131466 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 11237270 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27815605 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 25771023 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9153367 — Biomarker: TNFRSF1A
Type: Predictive Biomarker (PRD)
Genes: TNF-R; TNFAR; TNFR60; TNF-R-I; CD120a; TNF-R55
Study 9153367 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9153367 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29502856 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 28746179 — Biomarker: NUBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUBP1; NBP; NBP1
Study 31774112 — Biomarker: BTLA mRNA
Type: Predictive Biomarker (PRD)
Genes: BTLA
Study 30414369 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30414369 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30414369 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 19287288 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 10916570 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 29172605 — Biomarker: LTB4R mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 24985779 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1442757 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30626217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18076041 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15309442 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9223886 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 8267190 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31097085 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22884414 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 30520013 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 9797623 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 8592594 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 19185773 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8527549 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2273082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25823535 — Biomarker: Carbonic anhydrase IX
Type: Predictive Biomarker (PRD)
Genes: CA9; G250; MN
Study 15079108 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 11679441 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 18952561 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30444137 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 2633082 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 29915994 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 25581584 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 19462697 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 15001200 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8011800 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 2475681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15978968 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11840366 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11840366 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11840366 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9038563 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 26607249 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12403400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10454450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21252503 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16143120 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16143120 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11865835 — Biomarker: PEX19 mRNA
Type: Predictive Biomarker (PRD)
Genes: PEX19; HK33; PXF; OK/SW-cl.22
Study 10206296 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 10206296 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28918674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28918674 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22419733 — Biomarker: NPR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NPR3; ANPRC; C5orf23; NPRC
Study 2147736 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25125679 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9605995 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21654269 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 19781407 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7919329 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8570427 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2179650 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 30829734 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30829734 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 30829734 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22238353 — Biomarker: PTPRF mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRF; LAR
Study 20846991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20846991 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18094424 — Biomarker: SLC25A21 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A21; ODC
Study 12401583 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30906300 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 30906300 — Biomarker: HLA-DQB1
Type: Safety Biomarker (SAF)
Genes: IDDM1; CELIAC1
Study 21087222 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17885542 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12050092 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 29525239 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 23536950 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23200600 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23200600 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 9374129 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22836068 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22836068 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15958080 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15958080 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 7553993 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7553993 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1443441 — Biomarker: ALDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH2; ALDM
Study 31803473 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27087149 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27087149 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31812681 — Biomarker: ADIPOQ mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 19158194 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study 7986457 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21491295 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 19657294 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19657294 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17118826 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 22440640 — Biomarker: REG3A mRNA
Type: Predictive Biomarker (PRD)
Genes: REG3A; HIP; PAP; PAP1
Study 22440640 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 22440640 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1713352 — Biomarker: EDA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDA; ED1; EDA2
Study 19170452 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 11942969 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 11942969 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 11942969 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8657505 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 23377899 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 23377899 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 9781629 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19840568 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 8620097 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 25643432 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 22930403 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 22930403 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8466742 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8466742 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29930023 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21068682 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18445178 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18445178 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22122590 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16172794 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16172794 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10587476 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 22348388 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 7742579 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 2073001 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31287117 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21389144 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 19924586 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 9296731 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30275698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30275698 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22207105 — Biomarker: OPN mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SPP1; BNSP; OPN; PSEC0156
Study 9038610 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28511023 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 25529395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23072637 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 20957430 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8524969 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 2338695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23072847 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 18787516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12407324 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22819555 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 22819555 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 22819555 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 9345249 — Biomarker: MLXIPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MLXIPL; BHLHD14; MIO; WBSCR14
Study 30515403 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30515403 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30515403 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20855825 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28874133 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 23466656 — Biomarker: PRF1
Type: Predictive Biomarker (PRD)
Genes: PFP; P1; HPLH2
Study 11385064 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25861737 — Biomarker: PTGDR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 23471101 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 15867406 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15867406 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24740547 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 8115316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21118410 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 26237826 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 23419401 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19666435 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19666435 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19666435 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 2863295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22534255 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 22534255 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 20824184 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20824184 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 8645368 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9451346 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 3996194 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 31892533 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 31892533 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22354408 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20420907 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12401856 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12401856 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25469528 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 25469528 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 25469528 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2