AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 16421461 — Biomarker: DRD3
Type: Safety Biomarker (SAF)
Study 16791717 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10549447 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 8896646 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1725028 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29320971 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 29320971 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 24792382 — Biomarker: ALLC mRNA
Type: Predictive Biomarker (PRD)
Genes: ALLC
Study 15812738 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1760824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31767518 — Biomarker: APOB mRNA
Type: Predictive Biomarker (PRD)
Genes: APOB
Study 31767518 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 31767518 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29130954 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 19720909 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 11443156 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 9875631 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 2730280 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 28349250 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28349250 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23296629 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 23296629 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 23296629 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21955225 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19393142 — Biomarker: CALD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CALD1; CAD; CDM
Study 16289171 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 16372578 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17655695 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16338252 — Biomarker: LIPC mRNA
Type: Predictive Biomarker (PRD)
Genes: LIPC; HTGL
Study 16338252 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16338252 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17055561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15475599 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10445557 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 8695970 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 8695970 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8695970 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 2392980 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31087185 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22658571 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22136279 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22136279 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 22136279 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 22136279 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22136279 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 17347071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7741850 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16669842 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2996342 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18095949 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2870533 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 23078878 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18669816 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28759129 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 28759129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28759129 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20519876 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 20519876 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 17118684 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11004033 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27575565 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15657223 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25701454 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25701454 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23225026 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 17761356 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 8743519 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9375319 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 1554114 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25140908 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2124027 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 7004624 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31778314 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 15118486 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31692870 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 31692870 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26423732 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 26423732 — Biomarker: ARNT mRNA
Type: Predictive Biomarker (PRD)
Genes: ARNT; BHLHE2
Study 26423732 — Biomarker: Hypoxia-inducible factor 1-alpha
Type: Predictive Biomarker (PRD)
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 26423732 — Biomarker: JUN mRNA
Type: Predictive Biomarker (PRD)
Genes: JUN
Study 26423732 — Biomarker: NFAM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NFAM1; CNAIP
Study 26423732 — Biomarker: OSM mRNA
Type: Predictive Biomarker (PRD)
Genes: OSM
Study 26423732 — Biomarker: REL mRNA
Type: Predictive Biomarker (PRD)
Genes: REL
Study 1648849 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29018989 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 17581200 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 26918815 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26918815 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22789310 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 12970329 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12970329 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 9370111 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 1283591 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1283591 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2691476 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25504487 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 23779114 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 19845513 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29797519 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24257725 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18172059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31884075 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31884075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26137956 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 17584058 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29748349 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 29748349 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 27537209 — Biomarker: DDN mRNA
Type: Predictive Biomarker (PRD)
Genes: DDN; KIAA0749
Study 19723080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16951956 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 11559545 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8152348 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8152348 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28836493 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 26633830 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 30126028 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9733365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29726939 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22840987 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15715686 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15715686 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 8672354 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29310899 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20145598 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 7840079 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 29996800 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22130403 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 20442386 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18403672 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8985076 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8985076 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8501777 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 25280032 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 17369518 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 9988543 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 7859244 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7859244 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23481908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16864741 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12588772 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1770275 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 25148839 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 25148839 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 25148839 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25148839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16189630 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16189630 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12202465 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9036798 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9316182 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8487647 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8487647 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 8487647 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 8487647 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 2681882 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 19826135 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 8355460 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 8355460 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 8355460 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 8355460 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17555526 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 6167116 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29890048 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24198300 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24198300 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 24198300 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19395585 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 9536925 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2469243 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28685560 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 23815742 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21528596 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19210013 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 19210013 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 16845799 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 9815589 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 30633331 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 30633331 — Biomarker: S100A8 mRNA
Type: Predictive Biomarker (PRD)
Genes: S100A8; CAGA; CFAG; MRP8
Study 26011677 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 10460069 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 30696533 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 25091379 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25091379 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9610786 — Biomarker: GGN mRNA
Type: Predictive Biomarker (PRD)
Genes: GGN
Study 9610786 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 31286736 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 31286736 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 15565481 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8582541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30096704 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 19913325 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16118293 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16118293 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17594775 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7697252 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 21418799 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18222258 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 3885850 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31721447 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27552990 — Biomarker: DOCK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DOCK3; KIAA0299; MOCA
Study 21090334 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21090334 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21090334 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14719195 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30569662 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28650204 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 25905795 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 23943734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21257977 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27843047 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19852289 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19852289 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24092940 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17661847 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17661847 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2125252 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2125252 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19631773 — Biomarker: RUNX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX2; AML3; CBFA1; OSF2; PEBP2A
Study 7707108 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19609048 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19609048 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8574256 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 8574256 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study 8574256 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30027768 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20386309 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 12675869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1827418 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 9719037 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 3190800 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26386786 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 1310497 — Biomarker: EDNRA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDNRA; ETA; ETRA
Study 17344588 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17344588 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17344588 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7884791 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7884791 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28260202 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 21596605 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18000659 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 18000659 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 17010056 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9094871 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9094871 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)