AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 15346824 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11394510 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 22913893 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29879143 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27379733 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 20801248 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 19179739 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19179739 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 1463530 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29576535 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 11976195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9473971 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29278471 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 10591988 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 1657078 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26850307 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 12518931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7741289 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25710925 — Biomarker: SLC25A20 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A20; CAC; CACT
Study 10647797 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 24886116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16907968 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16907968 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8648396 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 1794947 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20863759 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 20863759 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30205182 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 31455149 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 16913827 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12025521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2393014 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 24338736 — Biomarker: NOS1AP mRNA
Type: Predictive Biomarker (PRD)
Genes: NOS1AP; CAPON; KIAA0464
Study 19657792 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12556688 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12556688 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 12556688 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 12556688 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 20646185 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12010906 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8826572 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 26547514 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24823873 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 10452757 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 10452757 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 28187051 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31945496 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 31945496 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 16914336 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 11358726 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 11358726 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 18077786 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12212206 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12212206 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3545116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23163982 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23163982 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23163982 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23163982 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 23163982 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20876317 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 16178642 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 10050702 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 2077498 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28117242 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 23773380 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 14988471 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18632424 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18632424 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18632424 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10840172 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9375951 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30074491 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18219956 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12057725 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12057725 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27067612 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23166441 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23166441 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19220959 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 17553207 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3028699 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18237574 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18237574 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2539762 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2539762 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24068631 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24068631 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19151379 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 26106626 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26106626 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 19964412 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 7871106 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 25473945 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 12619672 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 9255326 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 21736700 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 20687982 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16093575 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16093575 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16093575 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16093575 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 18090695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18070096 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 18070096 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18070096 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14691666 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 14691666 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 14691666 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 14691666 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31957251 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31184015 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16618361 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 6662172 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9576119 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9576119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28272227 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 28272227 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28272227 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24947057 — Biomarker: SLC12A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC12A3; NCC; TSC
Study 17366000 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17366000 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8194282 — Biomarker: DHFR
Type: Safety Biomarker (SAF)
Genes: DHFR1
Study 27928721 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26162698 — Biomarker: PHLDA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PHLDA2; BWR1C; HLDA2; IPL; TSSC3
Study 26162698 — Biomarker: CDKN1C mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN1C; KIP2
Study 26162698 — Biomarker: PEG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PEG3; KIAA0287; ZSCAN24
Study 26162698 — Biomarker: PEG10 mRNA
Type: Predictive Biomarker (PRD)
Genes: PEG10; EDR; KIAA1051e; MAR2; MART2; MEF3L1; RGAG3
Study 20540083 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 15541252 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15541252 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15564707 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15564707 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11773207 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9561680 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2722224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16148057 — Biomarker: GAD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD2; GAD65
Study 19544817 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 9535138 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9535138 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1325010 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9465478 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 24745696 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 11919227 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 7523778 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 7523778 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 7523778 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7523778 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11751732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31056148 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25444751 — Biomarker: HSPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPB1; HSP27; HSP28
Study 25444751 — Biomarker: ADAMTS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 22711752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18270944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15105167 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 11552922 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 26631004 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23332608 — Biomarker: PICALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PICALM; CALM
Study 18926434 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 11005229 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8973993 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1456384 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 30820005 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 30820005 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 30820005 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22787067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22787067 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22787067 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25847478 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11450709 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9506326 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9506326 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 29984137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18821691 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18821691 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7728627 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2045756 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25781618 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21354681 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21354681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18568578 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15890074 — Biomarker: RNPEP mRNA
Type: Predictive Biomarker (PRD)
Genes: RNPEP; APB
Study 29178536 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19171400 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16719158 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 11067784 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 6430768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29696423 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 26292778 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 19106238 — Biomarker: IPP mRNA
Type: Predictive Biomarker (PRD)
Genes: IPP; KLHL27
Study 19106238 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31477163 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31477163 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23000015 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19188252 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 19188252 — Biomarker: MKNK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MKNK1; MNK1
Study 15530681 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8572850 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8572850 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26016467 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 30544179 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30624670 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25384514 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22992330 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 17453342 — Biomarker: HOXB13 mRNA
Type: Predictive Biomarker (PRD)
Genes: HOXB13
Study 17453342 — Biomarker: IL17RB mRNA
Type: Predictive Biomarker (PRD)
Genes: IL17RB; CRL4; EVI27; IL17BR; UNQ2501/PRO19612
Study 17453342 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 171161 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11585118 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 11585118 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 11585118 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 8074426 — Biomarker: Protein AMBP
Type: Safety Biomarker (SAF)
Genes: AMBP; HCP; ITIL
Study 8074426 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28939427 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21415778 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17159108 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15251831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7736741 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30888253 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27148802 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 11053333 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31501493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18285411 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11944023 — Biomarker: COG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: COG2; LDLC
Study 11944023 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22135048 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 17224647 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17224647 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 15199361 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15199361 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12530261 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153