AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 7930484 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23184014 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 23184014 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 19001559 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 14676459 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20644555 — Biomarker: SERPINB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINB1; ELANH2; MNEI; PI2
Study 20644555 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 15114435 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 11978148 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19548273 — Biomarker: CGAS mRNA
Type: Predictive Biomarker (PRD)
Genes: CGAS; C6orf150; MB21D1
Study 18257185 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 10381299 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30845346 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27400947 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 27400947 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 27400947 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22102056 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31954837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29444778 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29444778 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25128283 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 19385024 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 7916546 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 2589241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26743856 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 26743856 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 26743856 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 16424116 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21284481 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 21284481 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21284481 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 16425182 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16425182 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10843245 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1568575 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 27043681 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10098822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9891896 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 2260915 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 21752315 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12475455 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 27100440 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27100440 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22234404 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15638877 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2271089 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26606263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15105059 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 25306290 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25306290 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24008977 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24008977 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21771256 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21771256 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15148541 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 15148541 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10364087 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8645434 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8645434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6416018 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31521192 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31521192 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29071949 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 25175124 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9671997 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 28645473 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 24595903 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24595903 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24595903 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19793846 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15213709 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 3521208 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3521208 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30552248 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8902551 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8902551 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 26984485 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 12617614 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 1317764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17414730 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17414730 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 16677798 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1327628 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 1327628 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 1327628 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1327628 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2427842 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27053325 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 24950358 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 22892455 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 22892455 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 22892455 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 22892455 — Biomarker: miR-155
Type: Safety Biomarker (SAF)
Genes: MIR155
Study 22892455 — Biomarker: miR-223
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR223
Study 22892455 — Biomarker: miR-125b
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22892455 — Biomarker: miR-146a
Type: Safety Biomarker (SAF)
Genes: MIR146A
Study 21095333 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21095333 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18678789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12413508 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 12413508 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 12413508 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 3119776 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 3119776 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 29428486 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 15879357 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 10475361 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 10475361 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 31987664 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24794243 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24794243 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 24794243 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 23036218 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 23036218 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 23036218 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7544732 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 7544732 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7544732 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2653971 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 20234144 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20234144 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 28991823 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 27823977 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 15485478 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15485478 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3880997 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31544803 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11190420 — Biomarker: ABCC8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC8; HRINS; SUR; SUR1
Study 11190420 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 6372737 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 27997586 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27997586 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 27997586 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22819406 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 3326679 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11413109 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 28724657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23977723 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16804032 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 16804032 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10981524 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9101380 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 9101380 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3298408 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18596069 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8840339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21352592 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21352592 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24703723 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 24703723 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 8767241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6225405 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 24189504 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 20933082 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 15632662 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15632662 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26614250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24204044 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12702897 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 29097438 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19679057 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19679057 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17356388 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17356388 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 17356388 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 15712717 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2659383 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28002684 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21127475 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9510582 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study 7857751 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28676100 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23475289 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27115063 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19192435 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 12162507 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 12162507 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24714414 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24714414 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21540583 — Biomarker: CPT1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CPT1A; CPT1
Study 21540583 — Biomarker: CPT1B mRNA
Type: Predictive Biomarker (PRD)
Genes: CPT1B; KIAA1670
Study 19843790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11449083 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11449083 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8030449 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28989150 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 20088415 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11689273 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11689273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21953376 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 22383739 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 11419108 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23807564 — Biomarker: NR1I2
Type: Predictive Biomarker (PRD)
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 23807564 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 23807564 — Biomarker: NR1I2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1I2; PXR
Study 1092725 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 12399193 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study 12399193 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9794569 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9794569 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7655643 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 2782327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1090415 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9059564 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 30056028 — Biomarker: SLC5A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A1; NAGT; SGLT1
Study 22872648 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9298772 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27216303 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27216303 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27216303 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30084962 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 29231364 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24410736 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19450157 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26301706 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 19816208 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28083972 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 21153029 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21153029 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15172408 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 11281231 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 11281231 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11281231 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29682590 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29682590 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27325864 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 27325864 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20053673 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 16084852 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 31607143 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24703195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25191556 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12069211 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS