AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 7717184 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 2149509 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 2149509 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 16901714 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15113716 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11795364 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9555667 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 20200547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8335833 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2967855 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 31517396 — Biomarker: Chitinase-3-like protein 1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: CHI3L1
Study 14734879 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14734879 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28259853 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 31912198 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 7915501 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 31504596 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 17426000 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17426000 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7879930 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7613114 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 7613114 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 2152972 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11805557 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7510078 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 2133624 — Biomarker: RETREG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RETREG2; C2orf17; FAM134A; MAG2
Study 30311367 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 28588304 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 21804623 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21804623 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 23731498 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 23731498 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 16901644 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 16901644 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 14604600 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 14604600 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31228006 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24096771 — Biomarker: Insulin receptor substrate 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IRS1
Study 11153048 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29371133 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 27347698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27347698 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 29906425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22197980 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22197980 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12002714 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 25460556 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 24060891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10506613 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 15790691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31756496 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 25388434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25388434 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 22762896 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21522004 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15459836 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23624785 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23624785 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 23624785 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 16813176 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 12932752 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 11038198 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 11038198 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 8777834 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27893473 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27893473 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22770377 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 20581169 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 20581169 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 15129736 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22935440 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 22935440 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25116461 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 2350628 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 30259172 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17261465 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15037412 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 24085261 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 21392603 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10556107 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 8818828 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1823530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1823530 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6827129 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 6827129 — Biomarker: Succinate-semialdehyde dehydrogenase
Type: Safety Biomarker (SAF)
Genes: ALDH5A1; SSADH
Study 27035157 — Biomarker: MCCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCCC2; MCCB
Study 19540162 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 31079533 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 28497384 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23331510 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 6398984 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10724301 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30712923 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22182296 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 7506007 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7506007 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 2554357 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25501057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15153576 — Biomarker: RAPGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 7957495 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7957495 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28857425 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28857425 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28857425 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23617712 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 28858247 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15817818 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 2898901 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1420630 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27509600 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2043298 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2043298 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6461999 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31348595 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 16718798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30916364 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30216191 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 2095345 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 30452776 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 23735727 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 16671435 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31623638 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27866873 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11169032 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9504950 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20525274 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 12441212 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6104874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17602978 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24570078 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16186280 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11018196 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1320241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30970186 — Biomarker: Beta-secretase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: BACE1; BACE; KIAA1149
Study 28339668 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 21892586 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19647104 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 9159839 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17403837 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 8584771 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28385543 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 28385543 — Biomarker: ABCG2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 25281416 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23448846 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12536732 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 25050884 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23333252 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 12567389 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12567389 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10680790 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 29784057 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 24328800 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study 23302603 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21272091 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 19541816 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8361890 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26198283 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25448515 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 27401037 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 27401037 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 16821204 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16821204 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11918754 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2789932 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 29432772 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29432772 — Biomarker: DSP mRNA
Type: Predictive Biomarker (PRD)
Genes: DSP
Study 29432772 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29432772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26555123 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23216520 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 20137557 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 20137557 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20137557 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20137557 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17367658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15253102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15253102 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11454260 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 31980145 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 25400085 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24576194 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21253451 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10150320 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28231660 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23273588 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 30509268 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 30509268 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18514620 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12074417 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12074417 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12074417 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 10385780 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10385780 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 28298024 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 28298024 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24517632 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20170522 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11911720 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29023938 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21573987 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 15235901 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7649670 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17465506 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17465506 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17465506 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25300285 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25300285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25300285 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25300285 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 25300285 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25300285 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 26859091 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 26859091 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 22948092 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22948092 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 22948092 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22948092 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11232964 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30396037 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26807502 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17687719 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31003676 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31003676 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25740387 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23497452 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22020892 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22020892 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 31665873 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29157276 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 3840565 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 3840565 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29587863 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25068290 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 20205486 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 20205486 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 8061266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8061266 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 18440325 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 18440325 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8814420 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 27136316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)