AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 3443058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12570114 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 1902159 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27753201 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29143667 — Biomarker: ALAS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALAS2; ALASE; ASB
Study 29143667 — Biomarker: BCL2L1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCL2L1; BCL2L; BCLX
Study 29143667 — Biomarker: DCAF12 mRNA
Type: Predictive Biomarker (PRD)
Genes: DCAF12; KIAA1892; TCC52; WDR40A
Study 29143667 — Biomarker: EPB42 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPB42; E42P
Study 29143667 — Biomarker: GMPR mRNA
Type: Predictive Biomarker (PRD)
Genes: GMPR; GMPR1
Study 29143667 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 29143667 — Biomarker: TMOD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMOD1; D9S57E; TMOD
Study 29143667 — Biomarker: TRIM58 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM58
Study 29143667 — Biomarker: CD247 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD247; CD3Z; T3Z; TCRZ
Study 23336474 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15281530 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 15281530 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 27832977 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23433430 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 23433430 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 21250913 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 19318900 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17365992 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 30719632 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23736112 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7718899 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 29741558 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29741558 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8815692 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3910768 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3910768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30486575 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 30486575 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 22854666 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 16036433 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 16036433 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 10676043 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31801155 — Biomarker: HRC mRNA
Type: Predictive Biomarker (PRD)
Genes: HRC; HCP
Study 17384205 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16088080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12106923 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 12106923 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12106923 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10579259 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1858944 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 21209539 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21209539 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 21209539 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31275984 — Biomarker: MUC22 mRNA
Type: Predictive Biomarker (PRD)
Genes: MUC22; G4; PBMUCL1
Study 31275984 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 31275984 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26796803 — Biomarker: Dihydrothymine dehydrogenase
Type: Safety Biomarker (SAF)
Genes: DPYD
Study 24525690 — Biomarker: GRIK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIK1; GLUR5
Study 15718405 — Biomarker: ACTN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACTN3
Study 27919222 — Biomarker: PDPN mRNA
Type: Predictive Biomarker (PRD)
Genes: PDPN; GP36; PSEC0003; PSEC0025
Study 8826928 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 24983892 — Biomarker: SNAP25 mRNA
Type: Predictive Biomarker (PRD)
Genes: SNAP25; SNAP
Study 11095454 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 9050888 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23592605 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20872345 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20872345 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 12783932 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 12783932 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12783932 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12783932 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 12783932 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22069289 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14514747 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9091692 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7692636 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7692636 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12142115 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12142115 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 7790321 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 31684880 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23149871 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 15242012 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 15242012 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 19049698 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 6353433 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26068514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29207087 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 29207087 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28627356 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 26286137 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26286137 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26286137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23135868 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21417623 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 19046244 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12763375 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31340094 — Biomarker: FGFR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 31340094 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study 27239035 — Biomarker: NELFCD mRNA
Type: Predictive Biomarker (PRD)
Genes: NELFCD; NELFD; TH1; TH1L; HSPC130
Study 17362556 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17362556 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17362556 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16379601 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10459959 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20702754 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 7636054 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 322905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26394188 — Biomarker: AJAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AJAP1; MOT8; SHREW1
Study 26394188 — Biomarker: PAX3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAX3; HUP2
Study 26394188 — Biomarker: EPHA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPHA4; HEK8; SEK; TYRO1
Study 26394188 — Biomarker: LBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LBX1; LBX1H
Study 15328251 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 15328251 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 9492500 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16133638 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 16133638 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 16133638 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12234091 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 26452709 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 22924372 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 22924372 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15249567 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9363379 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9363379 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30924492 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29079379 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 27616196 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 20697947 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 28019010 — Biomarker: MAP2K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K1; MEK1; PRKMK1
Study 28019010 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21479690 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21479690 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17710800 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15125121 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11246059 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7512100 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 27333970 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 25042878 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 25042878 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 22750403 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19325050 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 20721651 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11956264 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 2375296 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 2375296 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23635331 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17116511 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23418822 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 16927766 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 8836757 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30537951 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24211360 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24211360 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21178592 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 18326593 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 18326593 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28049699 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7856290 — Biomarker: CLSTN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLSTN1; CS1; KIAA0911
Study 7856290 — Biomarker: CLSTN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLSTN3; CS3; KIAA0726
Study 7856290 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study 30988133 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26961091 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 25549193 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 28952176 — Biomarker: TRPM8 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPM8; LTRPC6; TRPP8
Study 25676011 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 25676011 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 25676011 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25676011 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31837264 — Biomarker: SLC5A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A1; NAGT; SGLT1
Study 29098426 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28132008 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 23333772 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23333772 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23333772 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 23333772 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 23333772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17054068 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 28483270 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 17280633 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17280633 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11240976 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8923781 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 1098177 — Biomarker: OPN1SW mRNA
Type: Predictive Biomarker (PRD)
Genes: OPN1SW; BCP
Study 25527736 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 10659875 — Biomarker: Undetectable plasma HIV RNA
Type: Surrogate Endpoint (SUR)
Study 4063284 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 22922564 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15252741 — Biomarker: CARD16 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARD16; COP; COP1
Study 23411106 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23411106 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11906441 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 11906441 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 11906441 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9731794 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2897812 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31286802 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 19559401 — Biomarker: EDA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDA; ED1; EDA2
Study 19559401 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12967321 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30255188 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22486815 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 18571502 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18571502 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8952311 — Biomarker: ARX mRNA
Type: Predictive Biomarker (PRD)
Genes: ARX
Study 8952311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25252624 — Biomarker: Interleukin 4 receptor alpha
Type: Predictive Biomarker (PRD)
Genes: IL4R; IL4RA; 582J2.1
Study 25252624 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 16330788 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16330788 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23292315 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15047680 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20112821 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9272427 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27513651 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27513651 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23844570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30661687 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 15464258 — Biomarker: PARP9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PARP9; BAL; BAL1
Study 31744798 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31744798 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27784687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9552063 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 8151464 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17591563 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 23141816 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15219265 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9385624 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28408067 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23937144 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22788842 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 22788842 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12607659 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10232435 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 10232435 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 7057465 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24388622 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30092827 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27804264 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23992556 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1