AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 21321461 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17257478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11508581 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11508581 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11508581 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 2825820 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20028728 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12627998 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31222044 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 31222044 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 31313548 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22282500 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 22282500 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22282500 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 22282500 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 22282500 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 17324657 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 17324657 — Biomarker: MNT mRNA
Type: Predictive Biomarker (PRD)
Genes: MNT; BHLHD3; ROX
Study 28437278 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28437278 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16818564 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25029426 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25029426 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 11247198 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 31387629 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28862373 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 18260172 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15639293 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12189483 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12189483 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2140160 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21275446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16406239 — Biomarker: GJB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GJB2
Study 16406239 — Biomarker: GJB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GJB3; CX31
Study 16406239 — Biomarker: GJB6 mRNA
Type: Predictive Biomarker (PRD)
Genes: GJB6
Study 9018183 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29419875 — Biomarker: KIR2DL4 mRNA
Type: Predictive Biomarker (PRD)
Genes: KIR2DL4; CD158D; KIR103AS
Study 27512827 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20728875 — Biomarker: CHRNA7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA7; NACHRA7
Study 22019438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10787430 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10787430 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15913168 — Biomarker: ESD mRNA
Type: Predictive Biomarker (PRD)
Genes: ESD
Study 9579503 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 28804801 — Biomarker: INA mRNA
Type: Predictive Biomarker (PRD)
Genes: INA; NEF5
Study 24698195 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19058059 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8195853 — Biomarker: DHFR
Type: Safety Biomarker (SAF)
Genes: DHFR1
Study 19651631 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 29750828 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23403530 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20516425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6784976 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 6784976 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 6784976 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 31711489 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 20813019 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 12500883 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2715089 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25037854 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19256180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27793125 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10464529 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1867297 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28266821 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8217026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29700636 — Biomarker: MYCN mRNA
Type: Predictive Biomarker (PRD)
Genes: MYCN; BHLHE37; NMYC
Study 24925270 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 24925270 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24925270 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24925270 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20724431 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 31427688 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22588803 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22588803 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22588803 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 22588803 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 9920138 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28385185 — Biomarker: HLA-DQA1
Type: Safety Biomarker (SAF)
Genes: CELIAC1
Study 6872409 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6872409 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20863238 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12756020 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 8797150 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22435948 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22435948 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16186073 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16186073 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9074912 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15847101 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30615007 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 30983008 — Biomarker: CLEC4D mRNA
Type: Predictive Biomarker (PRD)
Genes: CLEC4D; CLECSF8; MCL
Study 22046271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21317165 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18835434 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 18835434 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9268221 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9268221 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 19804570 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15905896 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8733437 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27958220 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 20175014 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10533471 — Biomarker: MGAM mRNA
Type: Predictive Biomarker (PRD)
Genes: MGAM; MGA; MGAML
Study 19703819 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18025296 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11038407 — Biomarker: GHR mRNA
Type: Predictive Biomarker (PRD)
Genes: GHR
Study 24132900 — Biomarker: CHN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHN2; ARHGAP3; BCH
Study 24132900 — Biomarker: CPVL mRNA
Type: Predictive Biomarker (PRD)
Genes: CPVL; VLP; PSEC0124; UNQ197/PRO223
Study 24132900 — Biomarker: COL21A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL21A1; COL1AL; FP633
Study 24132900 — Biomarker: PYGL mRNA
Type: Predictive Biomarker (PRD)
Genes: PYGL
Study 24132900 — Biomarker: TRIM9 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM9; KIAA0282; RNF91
Study 12709127 — Biomarker: CARTPT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CARTPT; CART
Study 15462690 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15462690 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15462690 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8390369 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22774206 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2193318 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 9772944 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9772944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26797697 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26797697 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 18676693 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 19489494 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 12527970 — Biomarker: PCSK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK5; PC5; PC6
Study 12527970 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 12527970 — Biomarker: PSMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSMA1; HC2; NU; PROS30; PSC2
Study 27596132 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27596132 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11830339 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23911864 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 23911864 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23911864 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 23911864 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 15250255 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15250255 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15250255 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15250255 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15250255 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9315414 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27572290 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 21878082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19407662 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 14871464 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11728960 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11728960 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9210707 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 25641242 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16669959 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11728290 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8126257 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 8126257 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8126257 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 3110681 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 29618011 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28589493 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 12554889 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 24048485 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18388881 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 9814476 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9814476 — Biomarker: ESR1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ESR1; ESR; NR3A1
Study 2802123 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26222559 — Biomarker: APOC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOC3
Study 21875546 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18001802 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8443481 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 8443481 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29792287 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18927301 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 18927301 — Biomarker: NDRG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NDRG1; CAP43; DRG1; RTP
Study 18927301 — Biomarker: SLC7A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC7A5; CD98LC; LAT1; MPE16
Study 18927301 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 18927301 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 1472833 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26850265 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2169371 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 27770279 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24035872 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 19132882 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31256036 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 28291622 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25735400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23267856 — Biomarker: ERCC2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MAG; EM9; MGC102762; MGC126218; MGC126219
Study 19930866 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 19930866 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16825591 — Biomarker: PDE4D mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE4D; DPDE3
Study 26650153 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23908086 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23908086 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23908086 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23908086 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21890003 — Biomarker: SULT1A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SULT1A3; STM
Study 9237640 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 25434315 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18619828 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18619828 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9148226 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16122909 — Biomarker: USH1G mRNA
Type: Predictive Biomarker (PRD)
Genes: USH1G; SANS
Study 29981250 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25577762 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21257003 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21257003 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21257003 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19415804 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 23340588 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20931221 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9404747 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3422105 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28053714 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 24078975 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 12810502 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 8672321 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8672321 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 27787547 — Biomarker: Carbonic anhydrase IX
Type: Predictive Biomarker (PRD)
Genes: CA9; G250; MN
Study 12898792 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 1746428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31772615 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9822096 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 27072928 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11677363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29704456 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 6278914 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28026727 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 24678939 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19147138 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17071945 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 30460598 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17537217 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17537217 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17537217 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 10928463 — Biomarker: SERPINA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 10928463 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 9483810 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 23181634 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24585444 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 21652619 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 476231 — Biomarker: DBH mRNA
Type: Predictive Biomarker (PRD)
Genes: DBH
Study 29190761 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23948862 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21208928 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9669460 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 18311126 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6115999 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)