AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24716637 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 15110095 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 15110095 — Biomarker: SLC38A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 8056578 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 26518955 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 14727011 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2970805 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22968306 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17161060 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 17161060 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7576 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26417835 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 26417835 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 21673660 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 17183151 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 22539169 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21285133 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21285133 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21285133 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19720808 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17927859 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17927859 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 2850132 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2850132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24263123 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 14991636 — Biomarker: CGN mRNA
Type: Predictive Biomarker (PRD)
Genes: CGN; KIAA1319
Study 9209198 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2831320 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19548448 — Biomarker: STC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STC1; STC
Study 10093686 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26241349 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 26241349 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26241349 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 9492772 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30666827 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8275477 — Biomarker: Proliferation marker protein Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67
Study 24131095 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 22814178 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20659545 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 20659545 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17980273 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 29236273 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 25481673 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21926663 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21926663 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 21926663 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19953917 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19953917 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15131684 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 9438892 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27861157 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27861157 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15904635 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8158888 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8158888 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 17524938 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 11434169 — Biomarker: GAPDH mRNA
Type: Predictive Biomarker (PRD)
Genes: GAPDH; GAPD; CDABP0047; OK/SW-cl.12
Study 11434169 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 11434169 — Biomarker: REN mRNA
Type: Predictive Biomarker (PRD)
Genes: REN
Study 9596205 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3241216 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22972399 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11571237 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8112194 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23998657 — Biomarker: SLC4A7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC4A7; BT; NBC2; NBC2B; NBC3; NBCn1; SBC2; SLC4A6
Study 19628217 — Biomarker: IL2RG mRNA
Type: Predictive Biomarker (PRD)
Genes: IL2RG
Study 19628217 — Biomarker: JAK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK3
Study 19628217 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 19628217 — Biomarker: LIG4 mRNA
Type: Predictive Biomarker (PRD)
Genes: LIG4
Study 9322808 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22254230 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 29729672 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 10235220 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31876460 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22677260 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 20129543 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 27381968 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25881462 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 8432915 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 24072136 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24072136 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 24072136 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21902684 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18239240 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14709298 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30470229 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30470229 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27798770 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27798770 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20610550 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15718356 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10216805 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2196146 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 24107881 — Biomarker: CGAS mRNA
Type: Predictive Biomarker (PRD)
Genes: CGAS; C6orf150; MB21D1
Study 8001520 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8363067 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8363067 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 3539618 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30120066 — Biomarker: TLR9
Type: Predictive Biomarker (PRD)
Genes: CD289
Study 28318397 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 28318397 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26854974 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 26854974 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22044044 — Biomarker: KCNH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNH2; ERG; ERG1; HERG
Study 22044044 — Biomarker: AOX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AOX1; AO
Study 19387424 — Biomarker: SLC6A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 19387424 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 1345132 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25042199 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20189608 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20189608 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20189608 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16230877 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16230877 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12967694 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8706296 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 8706296 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 21900198 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 19473629 — Biomarker: Urinary total protein
Type: Safety Biomarker (SAF)
Study 31155953 — Biomarker: HDAC6 mRNA
Type: Predictive Biomarker (PRD)
Genes: HDAC6; KIAA0901; JM21
Study 31155953 — Biomarker: Cyclin-dependent kinase inhibitor 1
Type: Safety Biomarker (SAF)
Genes: CDKN1A
Study 31155953 — Biomarker: AMACR mRNA
Type: Predictive Biomarker (PRD)
Genes: AMACR
Study 24585506 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24585506 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22211733 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 11129341 — Biomarker: FAS mRNA
Type: Predictive Biomarker (PRD)
Genes: FAS; APT1; FAS1; TNFRSF6
Study 11129341 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 8839875 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8839875 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 20127540 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17650793 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 17650793 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2500070 — Biomarker: TAOK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 28679471 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28679471 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28679471 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 22964356 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 11204290 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27358210 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 17589281 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 17589281 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2592583 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29804376 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 28245911 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 28245911 — Biomarker: UCN mRNA
Type: Predictive Biomarker (PRD)
Genes: UCN
Study 21498674 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 19080708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1671884 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31825025 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 29576447 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 23235967 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20659762 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 10615220 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 26756278 — Biomarker: MAVS mRNA
Type: Predictive Biomarker (PRD)
Genes: MAVS; IPS1; KIAA1271; VISA
Study 24713402 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 20109071 — Biomarker: RAF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAF1; RAF
Study 20109071 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 20109071 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 1303482 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24403492 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24403492 — Biomarker: TIMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TIMP2
Study 24403492 — Biomarker: MMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP2; CLG4A
Study 24403492 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 24403492 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8750569 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 28852318 — Biomarker: CHM mRNA
Type: Predictive Biomarker (PRD)
Genes: CHM; REP1; TCD
Study 23630307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9427885 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 9427885 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3504725 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29067749 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 16553274 — Biomarker: RP9 mRNA
Type: Predictive Biomarker (PRD)
Genes: RP9
Study 2481787 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2481787 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25795285 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22473395 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 15111524 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 15111524 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30264480 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 28886437 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 28886437 — Biomarker: SLC5A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A1; NAGT; SGLT1
Study 20809859 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 19298319 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 1703237 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 18046434 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18046434 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18046434 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26888112 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 26888112 — Biomarker: ADRB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB3; ADRB3R; B3AR
Study 21037456 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21037456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17882161 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 17882161 — Biomarker: REEP5 mRNA
Type: Predictive Biomarker (PRD)
Genes: REEP5; C5orf18; DP1; TB2
Study 24290781 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17129220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20191820 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 12525736 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study 10978246 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10978246 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8421798 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 16184544 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25190617 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 19464001 — Biomarker: TMEM37 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMEM37; PR
Study 7953888 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29154814 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29154814 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29154814 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2212394 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 346042 — Biomarker: EMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EMP2; XMP
Study 28146397 — Biomarker: LHB mRNA
Type: Predictive Biomarker (PRD)
Genes: LHB
Study 24355450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19204412 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 19204412 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19204412 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8133020 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21629200 — Biomarker: CARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARS1; CARS
Study 17723076 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 9702445 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25259546 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25259546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29462733 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29462733 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 29462733 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30007544 — Biomarker: Bacteroidetes phylum
Type: Safety Biomarker (SAF)
Study 16364860 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7482648 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30276532 — Biomarker: PHC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PHC1; EDR1; PH1
Study 24976429 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24976429 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17950791 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 14769724 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 10714084 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 1389192 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24286801 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 24286801 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 18641189 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18641189 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 18641189 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18641189 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8848258 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 1411403 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 1411403 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 3318897 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)