AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 15602823 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27770188 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27770188 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 24490949 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17689142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26927249 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22332914 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10978986 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1610863 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24626733 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24626733 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21053992 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 23614849 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16549465 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31146305 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19894656 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11405344 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study 28838583 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 23335369 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 23335369 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 23335369 — Biomarker: BCL6 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 6144266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29867230 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23440143 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23440143 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26152757 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22465650 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 20565999 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 17629719 — Biomarker: GDNF mRNA
Type: Predictive Biomarker (PRD)
Genes: GDNF
Study 30393104 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 10501246 — Biomarker: HEXIM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: HEXIM2; L3
Study 8689808 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 30366115 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 21805588 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 30730896 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 25139195 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21628399 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 9314346 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 3521767 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30307466 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 30307466 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30307466 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 22544891 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 6151343 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28744111 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 21730017 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 18946429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30791735 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 2541159 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2541159 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 31561272 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 25759378 — Biomarker: CLDN7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLDN7; CEPTRL2; CPETRL2
Study 21947374 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11585004 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25742888 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 23004926 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 1571205 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15829577 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25736283 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 25736283 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25736283 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23444983 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 10975476 — Biomarker: Complement factor D
Type: Safety Biomarker (SAF)
Genes: CFD; DF; PFD
Study 12716487 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12716487 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11134132 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15157751 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15157751 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15157751 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9305603 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2423807 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31975638 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 26072289 — Biomarker: PSMB7 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSMB7; Z
Study 26072289 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 18789492 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 18789492 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18789492 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18789492 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 16305570 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 9708557 — Biomarker: SLC2A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A1; GLUT1
Study 2225366 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 2225366 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23985260 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30170956 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 31590924 — Biomarker: Fatty acid amide hydrolase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: FAAH; FAAH1
Study 25661195 — Biomarker: CXCR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR2; IL8RB
Study 23417515 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 11232592 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 11232592 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18000094 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12796135 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12796135 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31620886 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31620886 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24857206 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20357732 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20357732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15616085 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15616085 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15616085 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2231883 — Biomarker: STUB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STUB1; CHIP; PP1131
Study 26303520 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 12919178 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 12919178 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 813053 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23355629 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23355629 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17710816 — Biomarker: FAS mRNA
Type: Predictive Biomarker (PRD)
Genes: FAS; APT1; FAS1; TNFRSF6
Study 6321674 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22845337 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 16940886 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 15236618 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9379661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21654755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21654755 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16949481 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9180240 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9180240 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26154338 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16541243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12704403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9283061 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29373432 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 26522923 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24439972 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20212299 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8942420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27084855 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 27084855 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 24799054 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22814329 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2524360 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 2524360 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 27582078 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27582078 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 16882163 — Biomarker: CYP1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A1
Study 16882163 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 16882163 — Biomarker: CYP1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1B1
Study 16882163 — Biomarker: CYP2C18 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C18
Study 16882163 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 16882163 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 16882163 — Biomarker: CYP26A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP26A1; CYP26; P450RAI1
Study 16882163 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 12928710 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 11211541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6829481 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6829481 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15887009 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9799756 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28588021 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25881936 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2198211 — Biomarker: SULT1A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SULT1A3; STM
Study 333869 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28012035 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 19786646 — Biomarker: CYP4F2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP4F2
Study 19786646 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9099655 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30111294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26692193 — Biomarker: PTGDR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 22421745 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 15070939 — Biomarker: TNFRSF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1A; TNFAR; TNFR1
Study 15070939 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29431520 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29431520 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29431520 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 27611858 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 27611858 — Biomarker: AZGP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AZGP1; ZAG; ZNGP1
Study 27611858 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25281710 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 8903111 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 8903111 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 31794512 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 19531929 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19531929 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15465622 — Biomarker: Amyloid beta peptide (1-40)
Type: Pharmacodynamic Biomarker (PDY)
Genes: APP; A4; AD1
Study 11204435 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 11204435 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7905730 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 1463155 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23945905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10891823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8937963 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 8937963 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2868748 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30388041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20074276 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 17609872 — Biomarker: RAPGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 12229137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7752567 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 15166130 — Biomarker: Mitochondrial membrane potential
Type: Pharmacodynamic Biomarker (PDY)
Study 7974375 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 7974375 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 4580022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15540297 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19271169 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19271169 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16620350 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15006431 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9184265 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9184265 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 9184265 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9184265 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 30326764 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28455782 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 23379741 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15543449 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 3052167 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31785175 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 15288411 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 28689453 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26537218 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 14977817 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 20545993 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20545993 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12067917 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 31464525 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24666696 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 23082701 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 14680343 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14680343 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14680343 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24631057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22588047 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22588047 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18391640 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 1659253 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 31364872 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 3108355 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 3108355 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 1833897 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 26674998 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19852292 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19852292 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 791319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29348183 — Biomarker: Neuromedin-U
Type: Predictive Biomarker (PRD)
Genes: NMU
Study 27912875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24462735 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 21122701 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18294814 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16796928 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 16796928 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11126231 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)