AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 22814125 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19397632 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 15050905 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7502628 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11590482 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 11590482 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 31455229 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18637168 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9376575 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9376575 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24848838 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 18058480 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18058480 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12135223 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12135223 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21191361 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 19054806 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12359410 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 16913261 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 9051544 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16424842 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16424842 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16424842 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 16424842 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 16424842 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 16424842 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 1847704 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1847704 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 12947272 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19294953 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 29621660 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 26453914 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22228118 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15811481 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 21714585 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 21714585 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21714585 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2339203 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25791863 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21801476 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12196498 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7778543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7778543 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20034629 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20034629 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29266965 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 26440923 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26591679 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23180950 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 15793094 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 11934246 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 11934246 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 17179509 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14600553 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 14600553 — Biomarker: Succinate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: SDHD
Study 9366278 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9366278 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9366278 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 12225436 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 10223773 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 680588 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 680588 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 25596939 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23414585 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 23505176 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23505176 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17009533 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25626738 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25626738 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 25626738 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 2563321 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 23950589 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 14724157 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14724157 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18434902 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16215921 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7828379 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 22871888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18242616 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 18242616 — Biomarker: Macrophage inflammatory protein 1-alpha
Type: Monitoring Biomarker (MOI)
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 18242616 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8861689 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8861689 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 11512369 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3508329 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24630840 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 30074288 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 27513640 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19839000 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19839000 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19839000 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19839000 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15998749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10388246 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8671813 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31955859 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 31618331 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31125186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29578858 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 29578858 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 10221717 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 10221717 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8519717 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29295829 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20739842 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18467618 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 31335802 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27372432 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27372432 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 23356505 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12679359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23496861 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 15012688 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15012688 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 15012688 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15012688 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 24582071 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 15168040 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 15168040 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11248360 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 7585753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25823991 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 21151012 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7838916 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 28720079 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26174719 — Biomarker: NR1I2
Type: Predictive Biomarker (PRD)
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 26174719 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 26174719 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 9142590 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31783127 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study 17190414 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 14708047 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 14708047 — Biomarker: MLH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MLH1; COCA2
Study 14708047 — Biomarker: DNA mismatch repair protein MSH2
Type: Predictive Biomarker (PRD)
Genes: MSH2
Study 14708047 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 14708047 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 29299989 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28892496 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 25809413 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 25809413 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23496265 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20833549 — Biomarker: LGI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LGI1; EPT; UNQ775/PRO1569
Study 10728742 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3158674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29333721 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 12502672 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19270469 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19270469 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 2530384 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 29346597 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 29346597 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 24290606 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23662522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15989703 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11875707 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 11875707 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 9833957 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9833957 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 7621844 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 2143062 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 2143062 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26447155 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21812266 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 21812266 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17976096 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31490251 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 25601535 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18641208 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 10896881 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 27230727 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21373300 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21373300 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16634993 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16634993 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8877596 — Biomarker: BLVRA mRNA
Type: Predictive Biomarker (PRD)
Genes: BLVRA; BLVR; BVR
Study 8877596 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26142227 — Biomarker: AXL mRNA
Type: Predictive Biomarker (PRD)
Genes: AXL; UFO
Study 22701683 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8541200 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9529260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2534464 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11295026 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9399608 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29672567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26887645 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24749354 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23194103 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 9445494 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7599909 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 31511044 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21266669 — Biomarker: Macrophage inflammatory protein 1-alpha
Type: Monitoring Biomarker (MOI)
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 21266669 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 15217941 — Biomarker: CDH3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDH3; CDHP
Study 15217941 — Biomarker: Dihydrothymine dehydrogenase
Type: Safety Biomarker (SAF)
Genes: DPYD
Study 11263297 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 17290150 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 17290150 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29618459 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 20670842 — Biomarker: UCN mRNA
Type: Predictive Biomarker (PRD)
Genes: UCN
Study 20670842 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 20670842 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 18690760 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18690760 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15621120 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15621120 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11273951 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8388583 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 8388583 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 26832834 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 10813593 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 1899945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24965218 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24965218 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 2172402 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 26906703 — Biomarker: LGI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LGI1; EPT; UNQ775/PRO1569
Study 21028969 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21028969 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21028969 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17318893 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12008859 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 12008859 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28536308 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19524839 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 8917241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1842943 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6626441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25581388 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 18798083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1960234 — Biomarker: Hydroxyphenylpyruvate dioxygenase
Type: Safety Biomarker (SAF)
Genes: HPD; PPD
Study 31246713 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31246713 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 26432913 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15036669 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 26914134 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17981854 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 9752816 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23043965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10557001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7132728 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 7132728 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 27046445 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)