AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 25131305 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 25131305 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25131305 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18978624 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20518950 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20518950 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18090405 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6427057 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24850754 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 22133305 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 17496463 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17496463 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11783681 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11783681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31242517 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 23456778 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 16469989 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 10686210 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 9139617 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1536625 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 1536625 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6388305 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 24050577 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24050577 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11753809 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 9289303 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 2879969 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 21540740 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 18438830 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16284225 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14519177 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9185029 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30354579 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27433887 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 16045185 — Biomarker: WT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WT1
Study 9843458 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 19185772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15200448 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31900231 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15030297 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15030297 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30887844 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19890250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18327510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11394391 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 2500068 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 28708072 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24089379 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 21777745 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 17505029 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 15452837 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 15452837 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9669262 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23527561 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 23527561 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 15700744 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 1312769 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 1312769 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 2029499 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2029499 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22810046 — Biomarker: CSF1R mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF1R; FMS
Study 17103169 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15188945 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 23733668 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12948063 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 1857725 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26755682 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23529834 — Biomarker: DRG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRG2
Study 21739267 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 21739267 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 19125322 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 7638127 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21854192 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 16476042 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 16476042 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29808711 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23996482 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12009014 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2110411 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 24988118 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21777268 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 16937604 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23163146 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23163146 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17051504 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29414272 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23134222 — Biomarker: TNS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNS3; TEM6; TENS1; TPP
Study 20130603 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20130603 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 16706649 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12830461 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28780512 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 28780512 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 11046202 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 11046202 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8375360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25581217 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17135810 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 12071899 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 19234828 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7995781 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22132809 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12834519 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31427751 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31427751 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 31427751 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 20584263 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 28779269 — Biomarker: HHIP mRNA
Type: Predictive Biomarker (PRD)
Genes: HHIP; HIP; UNQ5825/PRO19644
Study 27129315 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24367008 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11887047 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 11887047 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10094221 — Biomarker: Th2 cell
Type: Safety Biomarker (SAF)
Study 27267403 — Biomarker: RIGI mRNA
Type: Predictive Biomarker (PRD)
Genes: RIGI; DDX58
Study 24512527 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15663545 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 15663545 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 2523870 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2523870 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31069457 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30481720 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27743855 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26907087 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11804984 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11804984 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 27475283 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27475283 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26202179 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 19651272 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 19651272 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9630000 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 10836913 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8770972 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28985109 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 7003391 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12927226 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12927226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31825895 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27921992 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 25102685 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 9639218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21292168 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 17186295 — Biomarker: PDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PDK4; PDHK4
Study 17186295 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 15248230 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8611664 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 19468742 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 7988249 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 21445680 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17249520 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11808059 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 23601499 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 23601499 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20625264 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20625264 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 16325777 — Biomarker: AQP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP7; AQP7L; AQP9
Study 20495438 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15985573 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 15985573 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 8902989 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 6275987 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 27217703 — Biomarker: TBC1D17 mRNA
Type: Predictive Biomarker (PRD)
Genes: TBC1D17
Study 27217703 — Biomarker: CCL3L3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL3L1; D17S1718; G0S19-2; SCYA3L1; CCL3L3
Study 27217703 — Biomarker: CYFIP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYFIP2; KIAA1168; PIR121
Study 27217703 — Biomarker: CD6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD6
Study 27217703 — Biomarker: STAT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT4
Study 27217703 — Biomarker: IGFBP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP7; MAC25; PSF
Study 19114869 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30242234 — Biomarker: PCSK7 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK7; LPC; PC7; PC8; SPC7
Study 19209987 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 29176684 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 21937420 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 12702550 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9952363 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7294770 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 7294770 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21668975 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30885256 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 30885256 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 23493898 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 19692680 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 15566590 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11130223 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15924982 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12486284 — Biomarker: HLA-DQB1
Type: Safety Biomarker (SAF)
Genes: IDDM1; CELIAC1
Study 8670319 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24836312 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22614874 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 22614874 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19739124 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 10704165 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 10704165 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12743150 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15730366 — Biomarker: SPARC mRNA
Type: Predictive Biomarker (PRD)
Genes: SPARC; ON
Study 27523814 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 23869585 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 8983613 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27902622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31356878 — Biomarker: Tropomyosin-related kinase A
Type: Pharmacodynamic Biomarker (PDY)
Genes: NTRK1; MTC; TRK; TRKA
Study 20472865 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 20472865 — Biomarker: Nasal potential difference
Type: Pharmacodynamic Biomarker (PDY)
Study 15886380 — Biomarker: Arachidonate 5-lipoxygenase activating protein
Type: Safety Biomarker (SAF)
Genes: ALOX5AP; FLAP
Study 15886380 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8704419 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 2360920 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 2360920 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30917842 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 29402332 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24203065 — Biomarker: MYOD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYOD1; BHLHC1; MYF3; MYOD
Study 24203065 — Biomarker: Growth/differentiation factor 8
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: MSTN; GDF8
Study 24203065 — Biomarker: FST mRNA
Type: Predictive Biomarker (PRD)
Genes: FST
Study 24203065 — Biomarker: FOXO3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXO3; FKHRL1; FOXO3A
Study 24203065 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 16087950 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 1449389 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 2869574 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 2869574 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23800880 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 6399891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14708444 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14708444 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8145430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27758064 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27758064 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22209967 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22209967 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2790538 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12928047 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11192361 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25604111 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25604111 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9152566 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9152566 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 29353543 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 29353543 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 17851566 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 17851566 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 8934367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10586091 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 10586091 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26449338 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 29913528 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27074340 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 22385586 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17198742 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 2609138 — Biomarker: Vitamin K-dependent protein C
Type: Safety Biomarker (SAF)
Genes: PROC
Study 25868877 — Biomarker: EMP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EMP1; B4B; TMP
Study 23991206 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 23991206 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 23991206 — Biomarker: CD47 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD47; MER6
Study 19248193 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19248193 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9543148 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 12088943 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9488197 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)