AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 9313596 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9313596 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8198055 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8198055 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23656707 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 3027905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25835002 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25835002 — Biomarker: CALD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CALD1; CAD; CDM
Study 25835002 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 25835002 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29713156 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 30107904 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26784323 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 25045936 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 25045936 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 22086300 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 19292654 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19292654 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19292654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17485599 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2527534 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 184377 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 25466509 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21689393 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 21689393 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 9140801 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9140801 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2142246 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 2142246 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 28825348 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 26831333 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25233668 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12077765 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 12077765 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 23226223 — Biomarker: CALD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CALD1; CAD; CDM
Study 15469651 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 3555650 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 17591020 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27102490 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20618247 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28122717 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28122717 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 28122717 — Biomarker: TLR2
Type: Predictive Biomarker (PRD)
Genes: TIL4; CD282
Study 19150378 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 9218185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29895491 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29895491 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1575006 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29171139 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 27643296 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23136163 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 2067505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26426636 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2285640 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30651130 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 22612913 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 19528286 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14674937 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 14674937 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18210765 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7486097 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26189118 — Biomarker: FBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBP1; FBP
Study 17374703 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15719220 — Biomarker: PRCP mRNA
Type: Predictive Biomarker (PRD)
Genes: PRCP; PCP
Study 9814462 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7665802 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 26895618 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26895618 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26895618 — Biomarker: VEGF
Type: Predictive Biomarker (PRD)
Genes: VEGFA; VEGF-A; VPF
Study 17461726 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 16602632 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 10456462 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 7604799 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 452941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30114658 — Biomarker: EXO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EXO1; EXOI; HEX1
Study 30114658 — Biomarker: DCLRE1A mRNA
Type: Predictive Biomarker (PRD)
Genes: DCLRE1A; KIAA0086; SNM1; SNM1A
Study 12719203 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22431582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12214151 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 26646828 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 14687360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8873503 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 1516840 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30362280 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 25670530 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25670530 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23418947 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 23418947 — Biomarker: FBXO32 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FBXO32
Study 11306778 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7942164 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2904754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2904754 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28628884 — Biomarker: Small-inducible cytokine A11
Type: Predictive Biomarker (PRD)
Genes: CCL11; SCYA11
Study 16144849 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9174467 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 9174467 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 9174467 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 30624598 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29739634 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 26993331 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 24495158 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 8949690 — Biomarker: PAAT mRNA
Type: Predictive Biomarker (PRD)
Genes: PAAT; C10orf88
Study 2044395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6796714 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16860698 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12664518 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10326070 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25074698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12149661 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 12149661 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 30824956 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study 19574102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2575369 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26156651 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23774238 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23774238 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10967698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8790198 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 27368882 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 10522131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1321859 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 27516476 — Biomarker: PPARG mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARG; NR1C3
Study 27516476 — Biomarker: NRF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRF1
Study 27516476 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 27516476 — Biomarker: AKT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT2
Study 27516476 — Biomarker: PTPN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPN1; PTP1B
Study 27516476 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16386524 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 16386524 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12048292 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 7608861 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 29096835 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25862777 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21498149 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19249153 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 19249153 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 19249153 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 9383182 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29556903 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20226890 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12584366 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12584366 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31957555 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 31515191 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 22933501 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21495900 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21495900 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11180010 — Biomarker: CXCR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR2; IL8RB
Study 11180010 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 11180010 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 11180010 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11180010 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11180010 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 10865416 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 10865416 — Biomarker: CD7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD7
Study 21869730 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 20569064 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16172596 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 9020535 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20195744 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17919634 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 1632166 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31539267 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28215413 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23270444 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 8600888 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 15157948 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15157948 — Biomarker: CSF1R mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF1R; FMS
Study 7920875 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31789711 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20505750 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19081890 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 29073785 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27091717 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21039933 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 18560524 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9189045 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 30457433 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 25306591 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10669150 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10669150 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 8797400 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 21906546 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21906546 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16214825 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 16214825 — Biomarker: ITPA mRNA
Type: Predictive Biomarker (PRD)
Genes: ITPA; C20orf37; My049; OK/SW-cl.9
Study 31203726 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27403645 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 24606097 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 19825207 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23349102 — Biomarker: Nqo1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: NQO1; DIA4; NMOR1
Study 23349102 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 27595528 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27595528 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 12872610 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 6113479 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28544128 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 25869284 — Biomarker: BTLA mRNA
Type: Predictive Biomarker (PRD)
Genes: BTLA
Study 23677919 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7944416 — Biomarker: ALPK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALPK1; KIAA1527; LAK
Study 7944416 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 27711048 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 15539964 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25560227 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 343181 — Biomarker: SHB mRNA
Type: Predictive Biomarker (PRD)
Genes: SHB
Study 15114770 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 11590384 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 15933856 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26400874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23755867 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10096047 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12707127 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29049611 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 2526271 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 23257734 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 16407508 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16407508 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16407508 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11320566 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24804364 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29420997 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18822620 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31522159 — Biomarker: ADAM8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM8; MS2
Study 23673091 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10993031 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1349485 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25399975 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 8167383 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8167383 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31664959 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 26362286 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 23870300 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 15516942 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 19577936 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18922381 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 12458654 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12458654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10520057 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 1791485 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18001210 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 10213125 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 393299 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7924466 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3057036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23624215 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23624215 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9527083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30551730 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 30551730 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 3440634 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 21621993 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 21621993 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12659241 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 20499131 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 15277317 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11896110 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2