AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 14975456 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 28813433 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 25573400 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12513914 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 12513914 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17611340 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 12052481 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 31222796 — Biomarker: CYP2E1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2E1; CYP2E
Study 31222796 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 17650790 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 14738236 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 9695720 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 21457668 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29167485 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 21680781 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 15200445 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8500917 — Biomarker: Trefoil factor 3
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TFF3; ITF; TFI
Study 28090293 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 22084312 — Biomarker: DAND5 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DAND5; CER2; CKTSF1B3; GREM3; SP1
Study 8873694 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28726810 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 27316679 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27316679 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17522603 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 2422744 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 26508298 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11961025 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7553634 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 7553634 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7553634 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7553634 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 23452523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14618645 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 14618645 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 1320259 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30964750 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27456983 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22310542 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7734104 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31469816 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 28492860 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28492860 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9763798 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7812072 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20693809 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10192656 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10192656 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 12480822 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 16139123 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2189903 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24113783 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 24113783 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11106884 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 6129933 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 6129933 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31471504 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29137107 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 29137107 — Biomarker: MGP mRNA
Type: Predictive Biomarker (PRD)
Genes: MGP; MGLAP; GIG36
Study 29137107 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29137107 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22552048 — Biomarker: CYP17A1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CYP17A1; CYP17; S17AH
Study 22552048 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 31314967 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10195319 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 10195319 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 6656327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31442936 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26864309 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 26864309 — Biomarker: UST mRNA
Type: Predictive Biomarker (PRD)
Genes: UST; DS2ST
Study 17268215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7477167 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7013060 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31163212 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30053031 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 30053031 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 30053031 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 30053031 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 6795049 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 22257523 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22257523 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22257523 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 12238823 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 7914733 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7914733 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 24766732 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18668408 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 18668408 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28125168 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 23312881 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9151028 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 7903975 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3153025 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3513667 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 26857646 — Biomarker: ACSM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACSM1; BUCS1; LAE; MACS1
Study 26857646 — Biomarker: AMACR mRNA
Type: Predictive Biomarker (PRD)
Genes: AMACR
Study 26857646 — Biomarker: CACNA1D mRNA
Type: Predictive Biomarker (PRD)
Genes: CACNA1D; CACH3; CACN4; CACNL1A2; CCHL1A2
Study 26857646 — Biomarker: DLX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DLX1
Study 26857646 — Biomarker: KLK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLK3; APS
Study 26857646 — Biomarker: PLA2G7 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G7; PAFAH
Study 26857646 — Biomarker: RHOU mRNA
Type: Predictive Biomarker (PRD)
Genes: RHOU; ARHU; CDC42L1; G28K; WRCH1; SB128
Study 26857646 — Biomarker: SPINK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPINK1; PSTI
Study 26857646 — Biomarker: TMPRSS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMPRSS2; PRSS10
Study 26857646 — Biomarker: TDRD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TDRD1
Study 12218725 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12218725 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12218725 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7557852 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 21288121 — Biomarker: ENPP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ENPP2; ATX; PDNP2
Study 15088884 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 12208482 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12208482 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12208482 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 12208482 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 1858760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21246575 — Biomarker: LIF mRNA
Type: Predictive Biomarker (PRD)
Genes: LIF; HILDA
Study 10739631 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 24641941 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24641941 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24641941 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19693550 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 17959861 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10613628 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 7159883 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25185754 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31286728 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 10608948 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30789386 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 9424977 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30256919 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 30256919 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19297430 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11161898 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16093403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16093403 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 7792016 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 26487585 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 8959628 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 8959628 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 18062586 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 10574605 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 10574605 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 19536889 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11770031 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 11770031 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2829953 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15692069 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 10068658 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 31913961 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 27125966 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 27125966 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20668324 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 16320974 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16363278 — Biomarker: PRF1
Type: Predictive Biomarker (PRD)
Genes: PFP; P1; HPLH2
Study 16363278 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11573666 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 1586105 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1586105 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 1586105 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31783900 — Biomarker: STAR mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAR; STARD1
Study 6420959 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17660154 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15855335 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 24513094 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22452789 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 22452789 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 2178643 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27759898 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 26423650 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23507186 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 19418213 — Biomarker: CHRM2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CHRM2
Study 25118597 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23554756 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19410716 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 15127083 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 28629318 — Biomarker: CDS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDS1; CDS
Study 9219211 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17323547 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10922234 — Biomarker: TNFR1B
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 10922234 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1506791 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25344520 — Biomarker: HDGFL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: HDGFL2; HDGF2; HDGFRP2; HRP2; UNQ785/PRO1604
Study 25135348 — Biomarker: NOTCH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOTCH2
Study 25135348 — Biomarker: C2CD4B mRNA
Type: Predictive Biomarker (PRD)
Genes: C2CD4B; FAM148B; NLF2
Study 25135348 — Biomarker: SLC30A8 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC30A8; ZNT8
Study 25135348 — Biomarker: SEC61A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEC61A2
Study 10977126 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28327140 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27701496 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 24067879 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14703417 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 3921279 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31007691 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26636393 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 26636393 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2007326 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2007326 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31420350 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28829488 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28829488 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28829488 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28481761 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15526380 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 15526380 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 10740417 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 10740417 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1778192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31029154 — Biomarker: WT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WT1
Study 26698157 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 25239028 — Biomarker: Hypoxia-inducible factor 1-alpha
Type: Predictive Biomarker (PRD)
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 23114134 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17721099 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22885913 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 21850690 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 19644398 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 12575553 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 9597406 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25541227 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8675921 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6396365 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 6396365 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 6396365 — Biomarker: Glutamate dehydrogenase
Type: Safety Biomarker (SAF)
Study 26825278 — Biomarker: MALT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MALT1; MLT
Study 24657991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11463590 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 173124 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19207889 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 9677811 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 7793393 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19602786 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9825973 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 656270 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 16955801 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 29996127 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23730881 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18394060 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16152824 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 12211224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10761326 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG