AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 15930482 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 10513801 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 19484170 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1395117 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27569734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15800921 — Biomarker: IGFBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP1; IBP1
Study 15800921 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 8954302 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 1772813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21351399 — Biomarker: SMPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMPD1; ASM
Study 21351399 — Biomarker: ABCC6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC6; ARA; MRP6
Study 10576139 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10576139 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 1986565 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 1986565 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 25065668 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 11338314 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22585886 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22585886 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22297687 — Biomarker: CDS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDS1; CDS
Study 22297687 — Biomarker: PRCP mRNA
Type: Predictive Biomarker (PRD)
Genes: PRCP; PCP
Study 12442921 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26669417 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24906585 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 24906585 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 16038456 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16038456 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16510610 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9298513 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 7914737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23246022 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23246022 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 20622656 — Biomarker: PDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PDK4; PDHK4
Study 20622656 — Biomarker: FOXO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXO1; FKHR; FOXO1A
Study 20622656 — Biomarker: Metallothionein-1A
Type: Predictive Biomarker (PRD)
Genes: MT1A; MT1S
Study 20622656 — Biomarker: MT1A mRNA
Type: Predictive Biomarker (PRD)
Genes: MT1A; MT1S
Study 18783301 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18783301 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18783301 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18783301 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16635593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16635593 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16635593 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14616319 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8521205 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19909427 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10701730 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9347592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2190251 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 31683483 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 21725881 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 16790652 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25044383 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10471824 — Biomarker: PRTN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRTN3; MBN
Study 14716800 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 23625113 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23625113 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23625113 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23625113 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 23625113 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9387348 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 2857212 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2857212 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 20153039 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 17512638 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2649120 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26815593 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 26815593 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 21474517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31439579 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 31439579 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 31439579 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31439579 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 11348605 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 11348605 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11348605 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9517940 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22255101 — Biomarker: FGA mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGA
Study 16797329 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19897063 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18414411 — Biomarker: Ribonucleoside-diphosphate reductase large subunit
Type: Predictive Biomarker (PRD)
Genes: RRM1; RR1
Study 18414411 — Biomarker: RRM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RRM2; RR2
Study 31772611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26068576 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24938526 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12200465 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 26226029 — Biomarker: PHAX mRNA
Type: Predictive Biomarker (PRD)
Genes: PHAX; RNUXA
Study 26226029 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19589241 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 19589241 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10197085 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20202489 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4048835 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 28683283 — Biomarker: TBK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TBK1; NAK
Study 21545459 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19701647 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27480840 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27480840 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 27480840 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11339912 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 11339912 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3894872 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21518220 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21518220 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21518220 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17068306 — Biomarker: TPI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPI1; TPI
Study 1442589 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22593231 — Biomarker: CXADR mRNA
Type: Predictive Biomarker (PRD)
Genes: CXADR; CAR
Study 21195290 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 8669676 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11533267 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 31350540 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 31350540 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 31350540 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27164830 — Biomarker: ABCC6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC6; ARA; MRP6
Study 23677794 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19953916 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 19953916 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 15071125 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 15071125 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24223352 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 23328189 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12612157 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 10960369 — Biomarker: CENPJ mRNA
Type: Predictive Biomarker (PRD)
Genes: CENPJ; CPAP; LAP; LIP1
Study 25828037 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21163921 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21163921 — Biomarker: STXBP5 mRNA
Type: Predictive Biomarker (PRD)
Genes: STXBP5; LLGL3
Study 21163921 — Biomarker: SCARA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SCARA5; UNQ2938/PRO28700
Study 21163921 — Biomarker: STAB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAB2; FEEL2; FELL; FEX2; HARE
Study 21163921 — Biomarker: STX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: STX2; EPIM; STX2A; STX2B; STX2C
Study 21163921 — Biomarker: TC2N mRNA
Type: Predictive Biomarker (PRD)
Genes: TC2N; C14orf47; MTAC2D1
Study 21163921 — Biomarker: CLEC4M mRNA
Type: Predictive Biomarker (PRD)
Genes: CLEC4M; CD209L; CD209L1; CD299
Study 17823443 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 17823443 — Biomarker: FADS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS1; FADSD5
Study 17823443 — Biomarker: FADS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS2
Study 17823443 — Biomarker: DGAT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DGAT2; HMFN1045; UNQ738/PRO1433
Study 11213870 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11213870 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 8675565 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 31052277 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 31052277 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 31052277 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 26115520 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23527597 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30010081 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 19531688 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 15157952 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15157952 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9591438 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 7887824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15450049 — Biomarker: TNFR1B
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 15450049 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15450049 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15450049 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24022373 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 21967830 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19757980 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19757980 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19757980 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3053896 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24184274 — Biomarker: MYL9 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MYL9; MLC2; MRLC1; MYRL2
Study 8882904 — Biomarker: CPE mRNA
Type: Predictive Biomarker (PRD)
Genes: CPE
Study 26995372 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17494885 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16334026 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 9935014 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 8678248 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31016887 — Biomarker: MYH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYH1
Study 31016887 — Biomarker: MYH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYH2; MYHSA2
Study 31016887 — Biomarker: MYH4 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYH4
Study 31016887 — Biomarker: TRIM63 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 31016887 — Biomarker: TRIM62 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM62
Study 31016887 — Biomarker: FBXO32 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FBXO32
Study 24989842 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 24989842 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 24989842 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 24989842 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 24989842 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 24989842 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2680866 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 25534960 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19804594 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 19804594 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 16735702 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15556150 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 9123740 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 21733304 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18388160 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 30633368 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 30633368 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 30633368 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 26274827 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23253886 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19786383 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 19786383 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 19786383 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 19786383 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11773988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8139472 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 26354678 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15367100 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21122851 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 21122851 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 17188883 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 17188883 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 9331000 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9331000 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7503183 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2196946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21592295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18089891 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18285358 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12723743 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1662325 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24923232 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 1092276 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 9438978 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8175973 — Biomarker: GAD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD2; GAD65
Study 2773967 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31408137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24367678 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17113831 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17113831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24742955 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12375668 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 27181565 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 23235363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12269790 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 10025924 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26306566 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26306566 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23429675 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 9891830 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 22044987 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 17197849 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 14747230 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14747230 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 14747230 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11133899 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 8141279 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 8141279 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26092311 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 22752050 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20964572 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 20964572 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 16418760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14593356 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT