AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 30900158 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 10892523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8808432 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 8403157 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26818228 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 26818228 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20448287 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1826095 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 1826095 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30683848 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 30683848 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 30683848 — Biomarker: IL1RN mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RN; IL1F3; IL1RA
Study 29524536 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 27377073 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30476963 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 28209169 — Biomarker: VIT mRNA
Type: Predictive Biomarker (PRD)
Genes: VIT; UNQ647/PRO1277
Study 20107201 — Biomarker: NR1I2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1I2; PXR
Study 19736596 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12768117 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10705267 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 27270872 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22014381 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22014381 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 22014381 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 22014381 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12621741 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12621741 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7582060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2476039 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17597037 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17597037 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11799368 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 11799368 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 31053570 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 29089038 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29089038 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 23350584 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 19223168 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8076921 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2676651 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25797356 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11726433 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29257028 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 27322401 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 18723437 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12830992 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9591486 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31418989 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25808980 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 23506356 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21679977 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18507878 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18507878 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15327191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8218764 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 31675478 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31675478 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 18217460 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11207173 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 7872728 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 29635505 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 22927555 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15869351 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 10598762 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1936753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26432128 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 23567660 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9500689 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2186630 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 2186630 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12796126 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12796126 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12796126 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10666136 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 31212365 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 29425373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27529510 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 17397435 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 17719472 — Biomarker: PRCP mRNA
Type: Predictive Biomarker (PRD)
Genes: PRCP; PCP
Study 14764771 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 14764771 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15019739 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 9486679 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23564803 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6123760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31054140 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 26086066 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 26086066 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23841265 — Biomarker: FGG mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGG; PRO2061
Study 19339779 — Biomarker: DCN mRNA
Type: Predictive Biomarker (PRD)
Genes: DCN; SLRR1B
Study 19339779 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 7911921 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 7911921 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25451890 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 25451890 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 22061864 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12921554 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9383256 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 28317149 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 28317149 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28317149 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 28317149 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 28317149 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 28317149 — Biomarker: MSR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MSR1; SCARA1
Study 28317149 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24105694 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 24105694 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 3685399 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 3289598 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23457535 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23457535 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23457535 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21273177 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 19446148 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7021992 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29508046 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 28692723 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 16681480 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 15566420 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 11406907 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11406907 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3277436 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27993154 — Biomarker: MIA mRNA
Type: Predictive Biomarker (PRD)
Genes: MIA
Study 27993154 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 24872223 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 24324573 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18929735 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 20182022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20182022 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18303097 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 2170963 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1091391 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 25581612 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19930853 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27501928 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20586028 — Biomarker: SERPINB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINB3; SCCA; SCCA1
Study 20586028 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20586028 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 10516450 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 7492123 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1958445 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 1958445 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 31868632 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23734250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7589011 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 7589011 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7589011 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1771612 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17261960 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11772811 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2672898 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15975314 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27403931 — Biomarker: FMO3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMO3
Study 27403931 — Biomarker: UGT2B15 mRNA
Type: Predictive Biomarker (PRD)
Genes: UGT2B15; UGT2B8
Study 27403931 — Biomarker: CYP51A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP51A1; CYP51
Study 16460244 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 8354894 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 8354894 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 30891654 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 25992488 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25992488 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 25992488 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 16960515 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7948054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28192629 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 15232813 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9609271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7611580 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2794058 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 11680667 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27702747 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study 27702747 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24500611 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19777316 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10098761 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 22997780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16350718 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 10438352 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2253196 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7114512 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7114512 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 30933867 — Biomarker: CARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARS1; CARS
Study 26375599 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 25086636 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25086636 — Biomarker: miR-21
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR21
Study 25086636 — Biomarker: miR-210
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR210
Study 17244786 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 11706524 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11706524 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 3591644 — Biomarker: TNFSF14 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF14; HVEML; LIGHT; UNQ391/PRO726
Study 27746370 — Biomarker: PDPN mRNA
Type: Predictive Biomarker (PRD)
Genes: PDPN; GP36; PSEC0003; PSEC0025
Study 8581790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21334033 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17721096 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17721096 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 14994390 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11773161 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30442551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24378475 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 22765978 — Biomarker: CPOX mRNA
Type: Predictive Biomarker (PRD)
Genes: CPOX; CPO; CPX
Study 18066957 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11907350 — Biomarker: ACAD8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAD8; ARC42; IBD
Study 28844508 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22647413 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10471565 — Biomarker: DHFR mRNA
Type: Predictive Biomarker (PRD)
Genes: DHFR
Study 10471565 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 10471565 — Biomarker: DHFR
Type: Safety Biomarker (SAF)
Genes: DHFR1
Study 8853530 — Biomarker: HDC mRNA
Type: Predictive Biomarker (PRD)
Genes: HDC
Study 31877117 — Biomarker: Mitochondrial frataxin
Type: Monitoring Biomarker (MOI)
Genes: FXN; FRDA; X25
Study 26543357 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23601899 — Biomarker: RYR1
Type: Safety Biomarker (SAF)
Genes: RYR; PPP1R137
Study 16990660 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7899678 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19806358 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19806358 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14658397 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9853926 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 7863813 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 2488472 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 26641099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23595161 — Biomarker: PICALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PICALM; CALM
Study 23595161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16950175 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16950175 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12161769 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 12161769 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 10450540 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 7759275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31411516 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 9112351 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 1547684 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 3157577 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24560760 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15503293 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 28431480 — Biomarker: HMBS mRNA
Type: Predictive Biomarker (PRD)
Genes: HMBS; PBGD; UPS
Study 22514211 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19460770 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15577621 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15577621 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 3133712 — Biomarker: MIA mRNA
Type: Predictive Biomarker (PRD)
Genes: MIA
Study 30335073 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 25387888 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 23157654 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9923569 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8067223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31216547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25925999 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15770435 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 8389738 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8389738 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17409909 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8784310 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341