AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 21664068 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 21664068 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 10737166 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9186317 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 30374129 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 27171324 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 20191257 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18360047 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18360047 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12638278 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 7288877 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 27097389 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 20882405 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20882405 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12419572 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27097156 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 27097156 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27421051 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21989330 — Biomarker: CCND1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND1; BCL1; PRAD1
Study 21989330 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 15750041 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 15750041 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 20696047 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12882706 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 12882706 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 12882706 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10999794 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21883497 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15207950 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9710873 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3241870 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 30204280 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 8010457 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31821667 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21508170 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19052126 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 8400608 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29664663 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 29664663 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24812434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22921287 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19321990 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 15362205 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 11848262 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10437260 — Biomarker: PLEK mRNA
Type: Predictive Biomarker (PRD)
Genes: PLEK; P47
Study 3279578 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29221470 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 19671875 — Biomarker: NANOS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS3; NOS3
Study 19671875 — Biomarker: Nqo1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: NQO1; DIA4; NMOR1
Study 19671875 — Biomarker: NQO2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NQO2; NMOR2
Study 19671875 — Biomarker: CBR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CBR3; SDR21C2
Study 9135704 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 7963510 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 7963510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2252171 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31259 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31259 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26080370 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9727571 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2140663 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 24100786 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24100786 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24100786 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24100786 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21757515 — Biomarker: GPSM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPSM2; LGN
Study 15477049 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11926203 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11926203 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7989900 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1233216 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31486684 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26195078 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 25205516 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 4469040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28000180 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 25583994 — Biomarker: ADCY9 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADCY9; KIAA0520
Study 25583994 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22947258 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17602078 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 9420397 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 29404806 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29404806 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 18996856 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11040224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31504526 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8297739 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7975663 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 7975663 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 378671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28039187 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 26028098 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 24382103 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11427642 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 3386845 — Biomarker: CARD16 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARD16; COP; COP1
Study 31512258 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 21534244 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21534244 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21534244 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16548084 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9931882 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 24005546 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 9432196 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 22692758 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20210368 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 6387286 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 25675560 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 21917634 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 7305784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28273933 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 22257422 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19463133 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19463133 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17963316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15359902 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7862918 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2570604 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 79761 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study 23672672 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17086470 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9217756 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9217756 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8424508 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27090436 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27090436 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21849206 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18353618 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 16249698 — Biomarker: ABCC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC1; MRP; MRP1
Study 16249698 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 21967254 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19567088 — Biomarker: GJB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GJB2
Study 9669421 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21931019 — Biomarker: Calgranulin B
Type: Predictive Biomarker (PRD)
Genes: S100A9; CAGB; CFAG; MRP14
Study 10589889 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25675559 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10812288 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 31757794 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 29733520 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19965540 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 19965540 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 19965540 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 15864137 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 12645717 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24392491 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 19253522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16012079 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 28067075 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22011265 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16089138 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16089138 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16089138 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 16089138 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 29874199 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29874199 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17461854 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15351193 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2504171 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 28712113 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28712113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28712113 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26158605 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 22067312 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 22103452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10420149 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 8076658 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11340104 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 30203440 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30203440 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24231272 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 7808833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2573295 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29561428 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28205449 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 28205449 — Biomarker: NTRK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NTRK2; TRKB
Study 28205449 — Biomarker: NTRK
Type: Predictive Biomarker (PRD)
Study 17716779 — Biomarker: BLM mRNA
Type: Predictive Biomarker (PRD)
Genes: BLM; RECQ2; RECQL3
Study 15533546 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15533546 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1741639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29433682 — Biomarker: SRM mRNA
Type: Predictive Biomarker (PRD)
Genes: SRM; SPS1; SRML1
Study 25706622 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25706622 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25706622 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8936492 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29808819 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 22385548 — Biomarker: RYR1
Type: Safety Biomarker (SAF)
Genes: RYR; PPP1R137
Study 22385548 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22385548 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1305042 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30872116 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 23764683 — Biomarker: FGFR1
Type: Predictive Biomarker (PRD)
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 8989196 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 29602140 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29602140 — Biomarker: Urokinase plasminogen activator surface receptor
Type: Monitoring Biomarker (MOI)
Genes: PLAUR; MO3; UPAR
Study 29602140 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28606915 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 23830392 — Biomarker: CASP9
Type: Predictive Biomarker (PRD)
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 16781218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9844098 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7536619 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 6993253 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28835058 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28835058 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 28835058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21425738 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21425738 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 23048018 — Biomarker: ENPP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ENPP2; ATX; PDNP2
Study 10336576 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 7482386 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31368282 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31368282 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 31368282 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 21085635 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21085635 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 18635912 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22302887 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 402275 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20353858 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 26385164 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18417739 — Biomarker: BSG mRNA
Type: Predictive Biomarker (PRD)
Genes: BSG; UNQ6505/PRO21383
Study 12534646 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 31018921 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 31018921 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 26766564 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2820626 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25258014 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20722556 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12823127 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 28665937 — Biomarker: TLR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR7; UNQ248/PRO285
Study 28665937 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 9205017 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9205017 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28679683 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 28679683 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 28679683 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 23505198 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23505198 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23505198 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 14987325 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26659934 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 21869712 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16865869 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 10853878 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9115000 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20144066 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25824543 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)