AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 15998708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12023684 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 12023684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31240591 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 31240591 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 8406151 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 27173100 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 24997182 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12767566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10877197 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8892714 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8892714 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8892714 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21636735 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21636735 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21636735 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 1255322 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24941787 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18206569 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7876659 — Biomarker: MAX mRNA
Type: Predictive Biomarker (PRD)
Genes: MAX; BHLHD4
Study 2227816 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 15507062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9722036 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31206301 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 19951602 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7844605 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25400681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17940860 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17940860 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 1366265 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1366265 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 3888836 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24246407 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 22124042 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 15389231 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15389231 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25664602 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 23388208 — Biomarker: RTN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RTN1; NSP
Study 28126360 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28126360 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 21429452 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 19479183 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 19479183 — Biomarker: KIT
Type: Predictive Biomarker (PRD)
Genes: CD117; SCFR; C-Kit
Study 19479183 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 19479183 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 19479183 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 19479183 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19479183 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19479183 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 9745404 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 9745404 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 21982663 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30914464 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 22608783 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22608783 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 10638770 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10638770 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23286246 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19480654 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19480654 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12536625 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 29882635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29952159 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29952159 — Biomarker: Nuclear factor erythroid 2-related factor 2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: NFE2L2; NRF2
Study 29952159 — Biomarker: PRKAA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKAA1; AMPK1
Study 29952159 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22098272 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22098272 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 22098272 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21286411 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1651993 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 1443864 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 18450803 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7495344 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 26154851 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17379122 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15613678 — Biomarker: CYP19A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 15613678 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11875051 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 11875051 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 11875051 — Biomarker: MMP12 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP12; HME
Study 8669887 — Biomarker: TAOK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 475947 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 30915462 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30915462 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 30915462 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 23414745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16800964 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 16800964 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 12240665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8305640 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30725015 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 7495392 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 27289009 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12459934 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27593709 — Biomarker: CDS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDS1; CDS
Study 20479948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20479948 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15925862 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 10516393 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 10516393 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1934440 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6366135 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18272912 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 18272912 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18272912 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 9531231 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30818931 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17490918 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11524308 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 27057866 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 27057866 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19090407 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 16632022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9387731 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 2991478 — Biomarker: MERTK mRNA
Type: Predictive Biomarker (PRD)
Genes: MERTK; MER
Study 30010061 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20577119 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20577119 — Biomarker: SCNN1A mRNA
Type: Predictive Biomarker (PRD)
Genes: SCNN1A; SCNN1
Study 2551622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31812289 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23547848 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23547848 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10986540 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10986540 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25588664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25397825 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 22915053 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22915053 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20860546 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 12444307 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6107057 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28969715 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24029871 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15187504 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 10937036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10937036 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2517718 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 2517718 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24862395 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 7625348 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27922453 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23079864 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 23079864 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 23079864 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21646646 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 19888785 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16920896 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 16920896 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 8114057 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8114057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2951019 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29450827 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 29450827 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22851563 — Biomarker: CRLF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CRLF2; CRL2; ILXR; TSLPR
Study 22851563 — Biomarker: CDKN2A mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2A; CDKN2; MTS1
Study 22851563 — Biomarker: IKZF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IKZF1; IK1; IKAROS; LYF1; ZNFN1A1
Study 22851563 — Biomarker: PAX5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAX5
Study 22851563 — Biomarker: ETV6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV6; TEL; TEL1
Study 22851563 — Biomarker: Retinoblastoma-associated protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: RB1
Study 22851563 — Biomarker: BTG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BTG1
Study 22851563 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 22851563 — Biomarker: P2RY8 mRNA
Type: Predictive Biomarker (PRD)
Genes: P2RY8
Study 19186329 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19186329 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19186329 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12606734 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 30347425 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 23104856 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10602891 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 10602891 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24103528 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 21438171 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 31106835 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19864407 — Biomarker: TCF7L2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCF7L2; TCF4
Study 15856361 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 15856361 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10482176 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7661176 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 7661176 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 25122430 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 8590551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20368909 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16044002 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10622646 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8620717 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8620717 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 6257941 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 19879035 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 1403033 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25660356 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20525942 — Biomarker: NE
Type: Predictive Biomarker (PRD)
Study 20573584 — Biomarker: SPN mRNA
Type: Predictive Biomarker (PRD)
Genes: SPN; CD43
Study 21545398 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11850304 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9988956 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31707634 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25857500 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14971716 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26928677 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 21796252 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29661196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28478972 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 28478972 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 16859226 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 16859226 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10389044 — Biomarker: SMC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMC2; CAPE; SMC2L1; PRO0324
Study 8912804 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26378561 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23283370 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9626919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7532742 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2894747 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6712450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9792282 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9792282 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 319326 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 319326 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16594930 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3390997 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 8256213 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 24773263 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19569965 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19569965 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 19569965 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19569965 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17289576 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 15356502 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 12195694 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 12195694 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 2808261 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27533964 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27533964 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21332798 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)