AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 20524719 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20524719 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20524719 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20524719 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18581961 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 16463989 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 7565455 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27236602 — Biomarker: POR mRNA
Type: Predictive Biomarker (PRD)
Genes: POR; CYPOR
Study 24697948 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 11680663 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31664441 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23062489 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23062489 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23062489 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 23062489 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23062489 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 18572351 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 12436372 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 3988967 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24763885 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27613719 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26350550 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24156306 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 21335007 — Biomarker: HFE mRNA
Type: Predictive Biomarker (PRD)
Genes: HFE; HLAH
Study 19352198 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 29579195 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 23539933 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15892271 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15892271 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 15892271 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 2258063 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 8420442 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8420442 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8420442 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20536518 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20536518 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20536518 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29239988 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 29239988 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29239988 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 31652875 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 19812445 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 15593395 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 15593395 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 15593395 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12730746 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2680843 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 16463847 — Biomarker: PCLO mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLO; ACZ; KIAA0559
Study 7594443 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7594443 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 23345623 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 18663500 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18663500 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1335539 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8527690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30144887 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 24585900 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9829449 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26633571 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26633571 — Biomarker: Proliferation marker protein Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67
Study 25272582 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22517399 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 12409967 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11256901 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24836758 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 22402971 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1574768 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 1574768 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 10506854 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 10506854 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 10506854 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8947397 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1911676 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6240831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6240831 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 29941498 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 17611310 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 24505102 — Biomarker: LSR mRNA
Type: Predictive Biomarker (PRD)
Genes: LSR; ILDR3; LISCH
Study 10460070 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10460070 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22541248 — Biomarker: Interleukin 4 receptor alpha
Type: Predictive Biomarker (PRD)
Genes: IL4R; IL4RA; 582J2.1
Study 31727675 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30835950 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14501546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10391658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2000739 — Biomarker: SKIC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SKIC2; DDX13; SKI2W; SKIV2; SKIV2L; W
Study 8918277 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2011945 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2011945 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 2011945 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 2011945 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 2011945 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 25137425 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 9797484 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9797484 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9797484 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25892016 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20034232 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 20034232 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 8205299 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8205299 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23490288 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23490288 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17698328 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 15309547 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 11145854 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8161479 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29991140 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 24798484 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 24798484 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 24798484 — Biomarker: Bacterial beta-glucuronidase
Type: Safety Biomarker (SAF)
Genes: uidA; gurA; gusA; b1617; JW1609
Study 1444724 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 1444724 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29514721 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 22569995 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 15808404 — Biomarker: CYP1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1B1
Study 15808404 — Biomarker: GSTA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTA1
Study 15808404 — Biomarker: Nqo1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: NQO1; DIA4; NMOR1
Study 15808404 — Biomarker: SLC38A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 10511370 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 8758241 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 25669986 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25669986 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25669986 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 18510696 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 18510696 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31195354 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19398935 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 17822820 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 15641045 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31261494 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 26470637 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8401500 — Biomarker: ZFY mRNA
Type: Predictive Biomarker (PRD)
Genes: ZFY
Study 29198060 — Biomarker: SLC6A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 1446958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18708731 — Biomarker: TAOK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 26490493 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 26490493 — Biomarker: HTRA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HTRA1; HTRA; PRSS11
Study 26490493 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 26490493 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 26490493 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 26490493 — Biomarker: COL8A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL8A1; C3orf7
Study 26490493 — Biomarker: RAD51B mRNA
Type: Predictive Biomarker (PRD)
Genes: RAD51B; RAD51L1; REC2
Study 9291414 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 29793800 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29793800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26730183 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 26730183 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2297344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2297344 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2297344 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23929521 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 19628206 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11678862 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 27582175 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18975322 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18975322 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 16021197 — Biomarker: ALPI mRNA
Type: Predictive Biomarker (PRD)
Genes: ALPI
Study 17383818 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 12574184 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12574184 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 10477245 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 14506621 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10385131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8895240 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 20537376 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27903520 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27903520 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20631407 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 20631407 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 16441928 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16441928 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16441928 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16511633 — Biomarker: Cathepsin S
Type: Pharmacodynamic Biomarker (PDY)
Genes: CTSS
Study 11127843 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11127843 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3304473 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 20820456 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 8927235 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 8927235 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20386325 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20386325 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 18672194 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 18672194 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18672194 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 12742805 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9689551 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9689551 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 9689551 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 7737258 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 28603225 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 28603225 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28603225 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 28603225 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28603225 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27399077 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 18797304 — Biomarker: SLC10A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC10A3; DXS253E; P3
Study 16189173 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10657578 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 10657578 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10657578 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10657578 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 8866634 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 1593512 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29923286 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22398753 — Biomarker: IPP mRNA
Type: Predictive Biomarker (PRD)
Genes: IPP; KLHL27
Study 22398753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30906562 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 30906562 — Biomarker: DDR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 30906562 — Biomarker: Synuclein alpha
Type: Pharmacodynamic Biomarker (PDY)
Genes: SNCA; NACP; PARK1
Study 30906562 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 21669016 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31434809 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26267590 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21222064 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21222064 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21222064 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21222064 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21222064 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16533286 — Biomarker: NAAA mRNA
Type: Predictive Biomarker (PRD)
Genes: NAAA; ASAHL; PLT
Study 29387874 — Biomarker: POU5F1 mRNA
Type: Predictive Biomarker (PRD)
Genes: POU5F1; OCT3; OCT4; OTF3
Study 20593350 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20593350 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20593350 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 16689755 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15558071 — Biomarker: DDC mRNA
Type: Predictive Biomarker (PRD)
Genes: DDC; AADC
Study 25362163 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20449538 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14738209 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29239867 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25549485 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25549485 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 25549485 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30856652 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 23363643 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 23363643 — Biomarker: MEA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MEA1; MEA
Study 19476583 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31678224 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 31678224 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)