AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 18332401 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16520350 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23249766 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23249766 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27368881 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27368881 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27368881 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 7669311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2279253 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 876918 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19638505 — Biomarker: MAP2K4 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K4; JNKK1; MEK4; MKK4; PRKMK4; SEK1; SERK1; SKK1
Study 11095445 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 3533025 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26823602 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26823602 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 26823602 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26823602 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 26823602 — Biomarker: Carbonic anhydrase IX
Type: Predictive Biomarker (PRD)
Genes: CA9; G250; MN
Study 26823602 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 22496207 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 22496207 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19085342 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1656517 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1656517 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 25311333 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 25311333 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 15969777 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6961762 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12324991 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2560283 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2560283 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 26436470 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 23599357 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 12196361 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2649124 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21947813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20696980 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11590519 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9453529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29366744 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29366744 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29366744 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 24685829 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 7692110 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 26679552 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 22119930 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 15078741 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 27575546 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15063399 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31599479 — Biomarker: GAS6 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAS6; AXLLG
Study 31599479 — Biomarker: AXL mRNA
Type: Predictive Biomarker (PRD)
Genes: AXL; UFO
Study 30672256 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26887115 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21922934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16749407 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16749407 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22682553 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 7781752 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7781752 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 7781752 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2194264 — Biomarker: SLC22A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A4; ETT; OCTN1; UT2H
Study 619948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6360431 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 6360431 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30323581 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 17506781 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17506781 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15945343 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 15945343 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 2082945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17953336 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16034041 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 10077414 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30262813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7944415 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7818111 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20104156 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 17328057 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17328057 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17328057 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 17328057 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 17328057 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15316583 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2653386 — Biomarker: CRYM mRNA
Type: Predictive Biomarker (PRD)
Genes: CRYM; THBP
Study 17356003 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9798343 — Biomarker: HLA-DQB1
Type: Safety Biomarker (SAF)
Genes: IDDM1; CELIAC1
Study 30745014 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31290727 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 18081859 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 29318418 — Biomarker: ERCC8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC8; CKN1; CSA
Study 18698280 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30680547 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28697211 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 21111685 — Biomarker: GSS mRNA
Type: Predictive Biomarker (PRD)
Genes: GSS
Study 11375342 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9163658 — Biomarker: SPX mRNA
Type: Predictive Biomarker (PRD)
Genes: SPX; C12orf39
Study 23011683 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16809727 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19932542 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2527543 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2527543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25930952 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 22027666 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 19910808 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10730020 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10730020 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29688139 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15967846 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21515866 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 18246390 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29423372 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18319306 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15944074 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15944074 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15944074 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 15944074 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 10073863 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1798006 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19605967 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 17890871 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15388575 — Biomarker: DUSP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DUSP2; PAC1
Study 21189109 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25363381 — Biomarker: Apolipoprotein A-IV
Type: Monitoring Biomarker (MOI)
Genes: APOA4
Study 11223117 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 11223117 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 21306285 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18769080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23155514 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23155514 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16358163 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16358163 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7815676 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 28399076 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25808741 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19125855 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19125855 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16959151 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9176747 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 3697832 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29074964 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 834966 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11583826 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30030480 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23665883 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24016546 — Biomarker: RHD mRNA
Type: Predictive Biomarker (PRD)
Genes: RHD
Study 18704555 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9351616 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9351616 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 9351616 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 9351616 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21036834 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26003642 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22289020 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 10950800 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10950800 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31900843 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31900843 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26139005 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23833852 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21092287 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 16628153 — Biomarker: CR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR2; C3DR
Study 12884193 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 29660425 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27096428 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study 27096428 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21846661 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 12556541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1653671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25370155 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25370155 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 23288881 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19421684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19421684 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12575569 — Biomarker: CHM mRNA
Type: Predictive Biomarker (PRD)
Genes: CHM; REP1; TCD
Study 7848794 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3243913 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3243913 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19319941 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 11111813 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11111813 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 11111813 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 11111813 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 24622426 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 24622426 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 24622426 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18236300 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7971477 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 27402560 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 749854 — Biomarker: CBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CBX1; CBX
Study 26611120 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22094449 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 19539099 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19539099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16432050 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9158080 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 31634178 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 22706623 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 19169336 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6369883 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6369883 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 29343012 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 30525226 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 30525226 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 30525226 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 27809345 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21914365 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 20456838 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20456838 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 17157857 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11789243 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1734794 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20547017 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15531566 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 15531566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17311305 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 17311305 — Biomarker: Retinoblastoma-associated protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: RB1
Study 7921429 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25499302 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 23446962 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11464255 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22781642 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 2434802 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 2434802 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30963205 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15577135 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15577135 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2888736 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22565005 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22565005 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12128107 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 30663593 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 29448072 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29448072 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 10830255 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 1727807 — Biomarker: RAB8A mRNA
Type: Predictive Biomarker (PRD)
Genes: RAB8A; MEL; RAB8
Study 1727807 — Biomarker: ELK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELK3; NET; SAP2
Study 16101180 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF