AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT02529670 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00297128 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01531361 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study NCT01531361 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT01531361 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01531361 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT01531361 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT01531361 — Biomarker: ROS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROS1; MCF3; ROS
Study NCT01728727 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT03006796 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03261570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01191281 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT03857607 — Biomarker: ATP1A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATP1A3
Study NCT05022043 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study NCT05022043 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04366713 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02639923 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study NCT02639923 — Biomarker: miR-16
Type: Safety Biomarker (SAF)
Study NCT00441480 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT00138229 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study NCT00138229 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT02919410 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study NCT03770780 — Biomarker: SAGE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAGE1; SAGE
Study NCT01489267 — Biomarker: ATXN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATXN1; ATX1; SCA1
Study NCT01302691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02177812 — Biomarker: KDM1A mRNA
Type: Predictive Biomarker (PRD)
Genes: KDM1A; AOF2; KDM1; KIAA0601; LSD1
Study NCT03938012 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT03938012 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study NCT03938012 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study NCT02920450 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study NCT01921452 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study NCT02822157 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study NCT01756430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01112982 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00927758 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study NCT03080051 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01627223 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT00003408 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT03251872 — Biomarker: PARP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PARP1; ADPRT; PPOL
Study NCT00126672 — Biomarker: TSC2
Type: Predictive Biomarker (PRD)
Genes: tuberin; LAM; PPP1R160
Study NCT01600794 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT02732223 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04083794 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01386567 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study NCT02540876 — Biomarker: CDKN2A mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2A; CDKN2; MTS1
Study NCT00228189 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study NCT01847079 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study NCT04227210 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT00212758 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03381625 — Biomarker: BMX mRNA
Type: Predictive Biomarker (PRD)
Genes: BMX
Study NCT01582958 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study NCT00722098 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT00722098 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT00801346 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03550365 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT03550365 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study NCT04367311 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study NCT04016987 — Biomarker: Serum hemoglobin A1C
Type: Surrogate Endpoint (SUR)
Study NCT00901589 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01819441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01819441 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT00005061 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02537223 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study NCT02537223 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02597192 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study NCT03628066 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03628066 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT02579902 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03385525 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02896192 — Biomarker: POMC mRNA
Type: Predictive Biomarker (PRD)
Genes: POMC
Study NCT02896192 — Biomarker: PCSK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK1; NEC1
Study NCT03290794 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT05906667 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00318370 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study NCT05655650 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study NCT05655650 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT02480504 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00703404 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00646555 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study NCT00646555 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT01090674 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study NCT01090674 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT00936793 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT05136040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03878381 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT00019214 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT02997462 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study NCT02001688 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT04328753 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study NCT02919917 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04572698 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT00321438 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study NCT02262338 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study NCT03152396 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04583969 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01194414 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT02480062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04545034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05204758 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05204758 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT02163772 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT03622541 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study NCT03212599 — Biomarker: ADAM10 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM10; KUZ; MADM
Study NCT01985711 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03009149 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT01603979 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study NCT01326676 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03732521 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02959853 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01126684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01234519 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT03696446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03696446 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03696446 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00666536 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02868255 — Biomarker: SIRPA mRNA
Type: Predictive Biomarker (PRD)
Genes: SIRPA; BIT; MFR; MYD1; PTPNS1; SHPS1; SIRP
Study NCT02868255 — Biomarker: CD47 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD47; MER6
Study NCT02547519 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT02936336 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03127553 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01956994 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04827615 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00390429 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01729663 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT04950660 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00535444 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01952288 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01603212 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT04212546 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study NCT01570062 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03914521 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00608881 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study NCT03892525 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study NCT03892525 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00343057 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study NCT02539719 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00412113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00412113 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02557334 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03077243 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study NCT03077243 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study NCT03269136 — Biomarker: TNFRSF17 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF17; BCM; BCMA
Study NCT01099098 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT01217879 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT03590093 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study NCT00001319 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00001319 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT03209011 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04717648 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02109328 — Biomarker: Aurora kinase A
Type: Predictive Biomarker (PRD)
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT02023918 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT02023918 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT01769625 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study NCT02699125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02376478 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00044993 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study NCT04518722 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02159339 — Biomarker: GFRA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GFRA1; GDNFRA; RETL1; TRNR1
Study NCT01674660 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00826371 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT03655301 — Biomarker: SLC47A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC47A2; MATE2
Study NCT03800498 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01363336 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT01363336 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02024477 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT02024477 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT02245464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04572893 — Biomarker: MYH7 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYH7; MYHCB
Study NCT04572893 — Biomarker: TTN mRNA
Type: Predictive Biomarker (PRD)
Genes: TTN
Study NCT01544478 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study NCT00000608 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02019745 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study NCT01316809 — Biomarker: MTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study NCT03891615 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02842541 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT01896661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00159380 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study NCT00477139 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02593461 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT02028234 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT00625014 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study NCT03946852 — Biomarker: MANF mRNA
Type: Predictive Biomarker (PRD)
Genes: MANF; ARMET; ARP
Study NCT03946852 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study NCT01547689 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT01042054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01718613 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study NCT03111589 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study NCT01226641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01994850 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study NCT00420342 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01855945 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study NCT00253929 — Biomarker: ADORA2A
Type: Safety Biomarker (SAF)
Genes: RDC8
Study NCT03082807 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03082807 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02945319 — Biomarker: SH3PXD2A mRNA
Type: Predictive Biomarker (PRD)
Genes: SH3PXD2A; FISH; KIAA0418; SH3MD1; TKS5
Study NCT04103905 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT04103905 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT01520285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02136550 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03185468 — Biomarker: UBC mRNA
Type: Predictive Biomarker (PRD)
Genes: UBC
Study NCT02947490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01212679 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study NCT03904576 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study NCT02106104 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT01695525 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02132598 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT03383913 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00173199 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01989572 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01346020 — Biomarker: SH3PXD2A mRNA
Type: Predictive Biomarker (PRD)
Genes: SH3PXD2A; FISH; KIAA0418; SH3MD1; TKS5
Study NCT00338260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01858597 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study NCT01858597 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study NCT01858597 — Biomarker: KLB mRNA
Type: Predictive Biomarker (PRD)
Genes: KLB
Study NCT02062476 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02062476 — Biomarker: Histone acetylation
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02062476 — Biomarker: miR-21
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR21
Study NCT00405236 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study NCT02345044 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00223912 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study NCT00223912 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04379323 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01337518 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study NCT02028676 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00185172 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00544804 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02302755 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study NCT03456830 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study NCT05154643 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study NCT02608697 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study NCT03230110 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03314233 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study NCT03800264 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02423252 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2