AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31016613 — Biomarker: ABCG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 31016613 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 23706433 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30695288 — Biomarker: GRAMD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRAMD4; DIP; KIAA0767
Study 29383596 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19604092 — Biomarker: ADRA2A mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRA2A; ADRA2R; ADRAR
Study 11403730 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9717054 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9717054 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2488099 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28690088 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9415540 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9415540 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 9415540 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 9415540 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 8214746 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21123447 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 20630505 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 15899653 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15899653 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 9523214 — Biomarker: FMR1
Type: Predictive Biomarker (PRD)
Genes: FMRP; FRAXA; MGC87458
Study 11009291 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8629306 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 1424170 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 29307093 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7508065 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7508065 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25515398 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20459697 — Biomarker: T-cell specific protein RANTES
Type: Safety Biomarker (SAF)
Genes: CCL5; D17S136E; SCYA5
Study 20459697 — Biomarker: Small-inducible cytokine A11
Type: Predictive Biomarker (PRD)
Genes: CCL11; SCYA11
Study 16146552 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 16146552 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29044707 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 29044707 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 24667664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24667664 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24667664 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24201169 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 24201169 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 24201169 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 17398194 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17398194 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17398194 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8722747 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 1818543 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22415888 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 22415888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19855266 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 19855266 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 7586113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24768112 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 20455705 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20455705 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17039265 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2146060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23635771 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 12001178 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 30053863 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11022056 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21289522 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 9663178 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 30720697 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26585940 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 24251363 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 24251363 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 18182665 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 26875003 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25400472 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18397680 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 18397680 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 11879258 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 19836995 — Biomarker: GAL3ST1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAL3ST1; CST
Study 17082240 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17082240 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15021839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7924757 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2867260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25692350 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 20042475 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 22049171 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20464816 — Biomarker: CFI mRNA
Type: Predictive Biomarker (PRD)
Genes: CFI; IF
Study 26919870 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24060523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15766828 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12183711 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21175981 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21175981 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21175981 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15095806 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11407078 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 9921004 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9480464 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 9480464 — Biomarker: PIR mRNA
Type: Predictive Biomarker (PRD)
Genes: PIR
Study 9480464 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9480464 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 30409085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30905230 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 22101698 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11317194 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3362176 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3362176 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9231892 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9231892 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30571562 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30571562 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25251676 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25251676 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21164045 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 29463098 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27064030 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20521348 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 16826020 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12792513 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 6377884 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24717919 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 19158225 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19158225 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10979879 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23757126 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 18685605 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30299473 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 30299473 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 18366642 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10573236 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31771375 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 28679741 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 20674309 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20674309 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1100535 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24084510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8603261 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25237124 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 10069193 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10069193 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29049868 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 25627090 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 25627090 — Biomarker: HTRA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HTRA1; HTRA; PRSS11
Study 2134545 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 31729976 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26441396 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 31868850 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 28012977 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 24285276 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14977339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10707788 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29137895 — Biomarker: TMPRSS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMPRSS13; MSP; TMPRSS11
Study 25517279 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27327441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15931612 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15931612 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15931612 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7473798 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 30373651 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24850606 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20669672 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12859378 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26429522 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23052890 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 9894716 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31944250 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 30958348 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 24393856 — Biomarker: RNF43 mRNA
Type: Predictive Biomarker (PRD)
Genes: RNF43
Study 24393856 — Biomarker: TOMM34 mRNA
Type: Predictive Biomarker (PRD)
Genes: TOMM34; URCC3
Study 24393856 — Biomarker: FOXM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXM1; FKHL16; HFH11; MPP2; WIN
Study 24393856 — Biomarker: MELK mRNA
Type: Predictive Biomarker (PRD)
Genes: MELK; KIAA0175
Study 24393856 — Biomarker: HJURP mRNA
Type: Predictive Biomarker (PRD)
Genes: HJURP; FAKTS; FLEG1; URLC9
Study 24393856 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 24393856 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 14557884 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 31802059 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 31802059 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12231575 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12231575 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12231575 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 10090187 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 7581096 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24318688 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21904901 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 17440020 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7983959 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 970902 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21388938 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 21388938 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21388938 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9198716 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 8464952 — Biomarker: C1QL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 31385000 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31385000 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29255930 — Biomarker: Amyloid beta peptide (1-40)
Type: Pharmacodynamic Biomarker (PDY)
Genes: APP; A4; AD1
Study 27060461 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 25292137 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22378727 — Biomarker: ABCG8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG8
Study 16422247 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19185633 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16733496 — Biomarker: ARID3B mRNA
Type: Predictive Biomarker (PRD)
Genes: ARID3B; BDP; DRIL2
Study 7955813 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 25675558 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 23754711 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8688261 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1840038 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 1840038 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 1840038 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 1840038 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15821920 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 28846563 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22311517 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22311517 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12163427 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12163427 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12163427 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 12163427 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30153598 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30153598 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27427877 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17719303 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 17719303 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15212623 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9604941 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25171664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1510645 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6611245 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28119757 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 28119757 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 20080470 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 18595261 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18595261 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11678968 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11678968 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7526753 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24998105 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21494228 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21494228 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18175740 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14649310 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26497857 — Biomarker: EHF mRNA
Type: Predictive Biomarker (PRD)
Genes: EHF; ESE3; ESE3B; ESEJ
Study 22834417 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 17662759 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7562887 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20236174 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 19560968 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST