AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 29446817 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 19081418 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19081418 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8942424 — Biomarker: SLC26A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC26A3; DRA
Study 29324776 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29324776 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10094216 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 2134116 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 30368018 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 24804272 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 10784382 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26963724 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26963724 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19258384 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19258384 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19258384 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15308521 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11355895 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9743816 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 11336165 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 26970723 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 16766587 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10404768 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 10404768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26200164 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17164979 — Biomarker: Dermal blood flow
Type: Pharmacodynamic Biomarker (PDY)
Study 3627579 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31919539 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26378118 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19172341 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 27545848 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23060506 — Biomarker: STT3A mRNA
Type: Predictive Biomarker (PRD)
Genes: STT3A; ITM1; TMC
Study 2822334 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27450392 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27450392 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16970100 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 11854874 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25900353 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11491421 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7625111 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 22959905 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 10595696 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2982491 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30962094 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 17920338 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12842242 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12842242 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30677788 — Biomarker: BMP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: BMP6; VGR
Study 10569656 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10569656 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10569656 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6856646 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27488327 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27488327 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11789207 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10937982 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31943768 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7664216 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1071694 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 14561539 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14561539 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11961238 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25755079 — Biomarker: Metallothionein-1A
Type: Predictive Biomarker (PRD)
Genes: MT1A; MT1S
Study 25755079 — Biomarker: SLC39A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC39A1; IRT1; ZIP1; ZIRTL; CGI-08; CGI-71
Study 19924786 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 10522995 — Biomarker: MENT mRNA
Type: Predictive Biomarker (PRD)
Genes: MENT; C1orf56; UNQ547/PRO1104
Study 19864219 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 17533210 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17533210 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25346373 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 20664274 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 20664274 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 20664274 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11910665 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 11910665 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 30550174 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 22294737 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18802718 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 8775573 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25005331 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 18631246 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 7554308 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 1974505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21048041 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 21048041 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 9124202 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8268729 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22464164 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9733272 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 9194649 — Biomarker: MENT mRNA
Type: Predictive Biomarker (PRD)
Genes: MENT; C1orf56; UNQ547/PRO1104
Study 9194649 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 30732920 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 24522623 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19008149 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 10423659 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8888660 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8888660 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 1848131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1848131 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 1848131 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6844367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20020622 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9062865 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3720569 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30340813 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 18339798 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 1839759 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26575696 — Biomarker: SLIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLIT1; KIAA0813; MEGF4; SLIL1
Study 26575696 — Biomarker: SLIT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLIT2; SLIL3
Study 26575696 — Biomarker: SLIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLIT3; KIAA0814; MEGF5; SLIL2; UNQ691/PRO1336
Study 20963638 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 20963638 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17351950 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 16278618 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7318359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26949703 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 26949703 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8684799 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 27787873 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 25421427 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11003358 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 26059337 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19663668 — Biomarker: FCER2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FCER2; CD23A; CLEC4J; FCE2; IGEBF
Study 19663668 — Biomarker: CRHR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CRHR1; CRFR; CRFR1; CRHR
Study 31064014 — Biomarker: NME1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NME1; NDPKA; NM23
Study 21492926 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10795728 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2061566 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 3842545 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24607708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22437792 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18333888 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 30219772 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 30219772 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 22377796 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18355324 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 15821191 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10802002 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1800760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27167369 — Biomarker: DDN mRNA
Type: Predictive Biomarker (PRD)
Genes: DDN; KIAA0749
Study 318952 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31177924 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18511165 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18511165 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26212719 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 26212719 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15838366 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31454159 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 28804048 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6312008 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31856714 — Biomarker: CORIN mRNA
Type: Predictive Biomarker (PRD)
Genes: CORIN; CRN; TMPRSS10
Study 357764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30327302 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 22679249 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22679249 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16600928 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1397716 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 29692005 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 24582046 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18779444 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 24213216 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20554120 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 31371810 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31371810 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29431535 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 17511759 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10070908 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10070908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28851320 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21466991 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15030537 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11486253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11486253 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1992551 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30677175 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26315303 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24393852 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2147637 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 2147637 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21378348 — Biomarker: Dihydrothymine dehydrogenase
Type: Safety Biomarker (SAF)
Genes: DPYD
Study 17389005 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17389005 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12915681 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8735854 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1720846 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6816333 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7970999 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 26947059 — Biomarker: RANGAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RANGAP1; KIAA1835; SD
Study 21510830 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11481401 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 25166623 — Biomarker: RGR mRNA
Type: Predictive Biomarker (PRD)
Genes: RGR
Study 16054887 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7609574 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 27991432 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 16153271 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16153271 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 12514672 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31599775 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 23062767 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 23062767 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 23062767 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12415583 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9836028 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9836028 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31012238 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 27874292 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15115421 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22938651 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 20531094 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16051518 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16051518 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8848409 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 8848409 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 8848409 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 2425204 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2425204 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 28881341 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 18513512 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11982444 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25131978 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16020923 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6928183 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22670856 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 18818309 — Biomarker: ICOS mRNA
Type: Predictive Biomarker (PRD)
Genes: ICOS; AILIM
Study 12355995 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12355995 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10648305 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 8551788 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 8551788 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31560580 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 31560580 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 29123208 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 29123208 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8389559 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8389559 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 24556095 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 12106837 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 28803710 — Biomarker: NPC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NPC1
Study 24191673 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4