AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 17682090 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 1974143 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10080158 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31500661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25897676 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 17278974 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17278974 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 24296423 — Biomarker: SLC38A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC38A3; G17; NAT1; SN1; SNAT3
Study 15703774 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11836455 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1959686 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6367380 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25425308 — Biomarker: USH1C mRNA
Type: Predictive Biomarker (PRD)
Genes: USH1C; AIE75
Study 11860914 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1432027 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30876946 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 30876946 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29854085 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 29854085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22852055 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19254123 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 17448057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26763917 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 24240777 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22093005 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 9163287 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 8424580 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31751317 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 27473187 — Biomarker: CYP2R1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2R1
Study 19448211 — Biomarker: Alpha-glutathione S-transferase
Type: Safety Biomarker (SAF)
Study 19448211 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24814382 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24814382 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24814382 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3306291 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3306291 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25821098 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study 16162683 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24614112 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22587593 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 22587593 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 22587593 — Biomarker: CCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR4; CMKBR4
Study 22587593 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22587593 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 22587593 — Biomarker: Macrophage inflammatory protein 1-alpha
Type: Monitoring Biomarker (MOI)
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 22587593 — Biomarker: C-C motif chemokine 4
Type: Monitoring Biomarker (MOI)
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 6994771 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12162603 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6465510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27672108 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 27672108 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 27672108 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 19880803 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 18945992 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12634581 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11314239 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8070823 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29280076 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 16444910 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16444910 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12750868 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 10496201 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1676246 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30015250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25160013 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31415883 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18272933 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 1473445 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31680600 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31680600 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 23810881 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 23810881 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19597054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7706609 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31373782 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 27699890 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 21766512 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18848434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18848434 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18240698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18240698 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18240698 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30400876 — Biomarker: ABCD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCD2; ALD1; ALDL1; ALDR; ALDRP
Study 18173144 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 18173144 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 15711601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11801552 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 10422932 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11300425 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8322777 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8322777 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18422590 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 18422590 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 18422590 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 18422590 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14976882 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 14976882 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14976882 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 14976882 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 3609849 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 30701878 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 8501142 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3687038 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23077042 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 15746650 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15746650 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 15746650 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 23720950 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21890226 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21890226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21890226 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 2523660 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2523660 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 848803 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21252704 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11049104 — Biomarker: PCLAF mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 9350846 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 29406835 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 23613810 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 23613810 — Biomarker: ANKK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANKK1; PKK2; SGK288
Study 31373648 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27666380 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23532097 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18227766 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16595356 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26085515 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 9207618 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9207618 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21700944 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8639796 — Biomarker: CLEC4D mRNA
Type: Predictive Biomarker (PRD)
Genes: CLEC4D; CLECSF8; MCL
Study 27650051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18347544 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 10652047 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10652047 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24667140 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 28489775 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study 21565138 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 15117407 — Biomarker: FGF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF4; HST; HSTF1; KS3
Study 9241103 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22079391 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 18386567 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18386567 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15723737 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15723737 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 8340155 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3032537 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28033130 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23819344 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25596179 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 24449105 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15043687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25780062 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23304686 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 23304686 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 17341565 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 15761754 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 15761754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10207208 — Biomarker: VCP mRNA
Type: Predictive Biomarker (PRD)
Genes: VCP
Study 2140961 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2140961 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23894865 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21646599 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16410677 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 28830428 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 28830428 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 9223734 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9223734 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 3072419 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3072419 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 3072419 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30324975 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2285641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29146139 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17704027 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12602532 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12602532 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22966894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16195478 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 16195478 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24806033 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23257888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21329495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19253124 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 6310241 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6310241 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 20135645 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 16046714 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 11783152 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26689707 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 16139403 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3061400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29709643 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 29709643 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28933961 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 28933961 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28933961 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 28933961 — Biomarker: Proliferation marker protein Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67
Study 19956091 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 11320369 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11320369 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10322821 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 8494577 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8494577 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 25829142 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20005355 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22329591 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7760888 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 7760888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 85937 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21851461 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21851461 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21851461 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17239888 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17239888 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27161750 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 8606813 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8606813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26899019 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 26899019 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 22608107 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20573633 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 6191948 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 25376639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11597376 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30012391 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27618090 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27618090 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25172950 — Biomarker: CACNA1C mRNA
Type: Predictive Biomarker (PRD)
Genes: CACNA1C; CACH2; CACN2; CACNL1A1; CCHL1A1
Study 10319076 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8732324 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8517385 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8517385 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26860807 — Biomarker: CHM mRNA
Type: Predictive Biomarker (PRD)
Genes: CHM; REP1; TCD
Study 25130788 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25130788 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25130788 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25130788 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 25130788 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 19342701 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 23477205 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20942666 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2164204 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 17565634 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 19237249 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 26486702 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26486702 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 24199974 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24199974 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 8557971 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8657524 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 1632391 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31375452 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 27236883 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15861352 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15861352 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)