AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 22930049 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 9498441 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21300930 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 12913194 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8461269 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 28796885 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 26903255 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17302253 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 14502840 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 22096031 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 22096031 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 18815445 — Biomarker: DCC mRNA
Type: Predictive Biomarker (PRD)
Genes: DCC; IGDCC1
Study 26771522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22785114 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 29989171 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 19382890 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9669786 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9669786 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9669786 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7915090 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18505169 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18505169 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16783561 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 16783561 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 14666027 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 29869556 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 29869556 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29869556 — Biomarker: MYD88 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYD88
Study 29869556 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 18792100 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 6148005 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10382080 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10382080 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18412989 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11187414 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9536540 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11837758 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 31481504 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 21950653 — Biomarker: DMA mRNA
Type: Predictive Biomarker (PRD)
Genes: DMA; HLA-DMA; hCG_2001572
Study 10651170 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 7666090 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 26041862 — Biomarker: CHKA mRNA
Type: Predictive Biomarker (PRD)
Genes: CHKA; CHK; CKI
Study 10029243 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19387398 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19387398 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 19387398 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7835116 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 21496064 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 21496064 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 30703190 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 25482300 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17408310 — Biomarker: KCNH2
Type: Safety Biomarker (SAF)
Genes: Kv11.1; HERG; erg1
Study 15012622 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 11710890 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 11710890 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 11710890 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 7949808 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28950757 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24562444 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24562444 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24562444 — Biomarker: Carbonic anhydrase IX
Type: Predictive Biomarker (PRD)
Genes: CA9; G250; MN
Study 17114205 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 14574343 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22232535 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 20576462 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 20576462 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 20576462 — Biomarker: LGI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LGI1; EPT; UNQ775/PRO1569
Study 31246976 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8768057 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 24789859 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 24789859 — Biomarker: WAP four-disulfide core domain protein 2
Type: Predictive Biomarker (PRD)
Genes: WFDC2; HE4; WAP5
Study 22252020 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 1685667 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7913731 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7913731 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 31190322 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27322592 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 23040783 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 23040783 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7541190 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 7541190 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 18591167 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23622019 — Biomarker: HBE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HBE1; HBE
Study 20589679 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 19526158 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17502045 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23633524 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 1488663 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 29878043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27281699 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15879361 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 12569213 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8634167 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30922327 — Biomarker: GPC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPC3; OCI5
Study 19951570 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19951570 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19951570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30593882 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 26849270 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21920532 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17254923 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7737228 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 23271901 — Biomarker: FMOD mRNA
Type: Predictive Biomarker (PRD)
Genes: FMOD; FM; SLRR2E
Study 19827649 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19827649 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 19827649 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26843390 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 24595630 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 19514558 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 31995812 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 29047145 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 21078806 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 21078806 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study 15806416 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15806416 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 15806416 — Biomarker: Interleukin 1 alpha
Type: Safety Biomarker (SAF)
Genes: IL1A; IL1F1
Study 15806416 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 15806416 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 17391168 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8571077 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16822110 — Biomarker: GAL3ST1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAL3ST1; CST
Study 11948003 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 26149189 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26149189 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21659360 — Biomarker: ACOX3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACOX3; BRCOX; PRCOX
Study 21659360 — Biomarker: CENPF mRNA
Type: Predictive Biomarker (PRD)
Genes: CENPF
Study 21659360 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 21659360 — Biomarker: IL22RA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL22RA2; UNQ5793/PRO19598/PRO19822
Study 18022303 — Biomarker: SIGLEC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIGLEC1; SN
Study 12013322 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20806988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17851996 — Biomarker: PPOX
Type: Safety Biomarker (SAF)
Genes: HCRT; OX
Study 2180271 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 2180271 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 453982 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20962614 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1642023 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6403965 — Biomarker: CPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPZ
Study 23526980 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11113401 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3297472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3297472 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 29211295 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 27350298 — Biomarker: MMD mRNA
Type: Predictive Biomarker (PRD)
Genes: MMD; PAQR11
Study 27350298 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 27350298 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25006069 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 23880340 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 20577753 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 17664372 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 665565 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31455295 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25940230 — Biomarker: TCF7L2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCF7L2; TCF4
Study 25940230 — Biomarker: APOA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOA2
Study 25940230 — Biomarker: MLXIPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MLXIPL; BHLHD14; MIO; WBSCR14
Study 25940230 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 25940230 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 25940230 — Biomarker: GCKR mRNA
Type: Predictive Biomarker (PRD)
Genes: GCKR
Study 25940230 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 7522283 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2891533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12830458 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 12830458 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10390406 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 30856025 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21737561 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 31062731 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 18212314 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 10642232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7506580 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7506580 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 7506580 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7506580 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31925317 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 31925317 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 23953523 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8258676 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30675708 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 18833861 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 28497265 — Biomarker: Cytoplasmic malate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: MDH1; MDHA
Study 30623568 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 24300544 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24300544 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19710187 — Biomarker: EBF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF3; COE3
Study 19710187 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10586916 — Biomarker: MTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MTM1; CG2
Study 28604824 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27206951 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17268695 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15470329 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 26624824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12700622 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12700622 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12700622 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12700622 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 20152050 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 18230015 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 23116213 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 335093 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27427555 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 26011919 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16624773 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11411461 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9236426 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2890525 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20447934 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20447934 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 20447934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18166815 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18166815 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14632754 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14632754 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 8721025 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 19434815 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15447921 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17429083 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 17429083 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17429083 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26288120 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 12502673 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2321506 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25522302 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 30893159 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 11056095 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 8712118 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8712118 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1827000 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1827000 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24947112 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 22710369 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22710369 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9715777 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26223493 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 8380185 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 8380185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8380185 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3953429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27920513 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22618094 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 28668575 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 26714417 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26714417 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 18828959 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17007384 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17007384 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 17007384 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 14508195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14508195 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 27378312 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4028627 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)