AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 21818634 — Biomarker: TNFRSF1A
Type: Predictive Biomarker (PRD)
Genes: TNF-R; TNFAR; TNFR60; TNF-R-I; CD120a; TNF-R55
Study 6364879 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12092742 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12092742 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12092742 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 26021226 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 26021226 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 26021226 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 26021226 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9544865 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31518640 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 31518640 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 28329334 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18043700 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 3404500 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21929307 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 8292702 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8292702 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 24430787 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10852458 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 8449049 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24878942 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24878942 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24878942 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20190383 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21868730 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19154802 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 19154802 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 28110412 — Biomarker: IGFBP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP7; MAC25; PSF
Study 8070497 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8070497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15578470 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 15578470 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11453957 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9209724 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28268074 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 26536057 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 17012141 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 7015795 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20717875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20717875 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12851876 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 8740244 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 28209040 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 19573637 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 23388527 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 17012419 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9235470 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 1604411 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 22867101 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7553405 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7553405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27241125 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 27241125 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27241125 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27241125 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24935272 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 22343498 — Biomarker: BAD mRNA
Type: Predictive Biomarker (PRD)
Genes: BAD; BBC6; BCL2L8
Study 16224157 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 21088595 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15470213 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 28190788 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16504957 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15575830 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 6439759 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 6439759 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 10657535 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 10657535 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 8527287 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 8527287 — Biomarker: OMD mRNA
Type: Predictive Biomarker (PRD)
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 30835822 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 22232815 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 1540729 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1540729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30429415 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 21832111 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 15289792 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 31786810 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 28715540 — Biomarker: Dihydrothymine dehydrogenase
Type: Safety Biomarker (SAF)
Genes: DPYD
Study 28715540 — Biomarker: MACF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MACF1; KIAA0754
Study 28715540 — Biomarker: SPRY2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPRY2
Study 28715540 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15898218 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28543873 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 28543873 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22832429 — Biomarker: IRF7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRF7
Study 9072600 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 27207965 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22944873 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15377472 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9590570 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9590570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24656288 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 22410401 — Biomarker: AOX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AOX1; AO
Study 15723993 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 11137103 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11137103 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8059505 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 27468867 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27468867 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 26233572 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 19110788 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 8471818 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3402353 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28097295 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17299064 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17299064 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17299064 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17299064 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7750429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31883223 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 30509771 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 30509771 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30292279 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 26808474 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24471979 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 16297748 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9705040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24095239 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21970555 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21970555 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 21970555 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21970555 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 21970555 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10868823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8844349 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 1321186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1321186 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 23770470 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 16553675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2853764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12769163 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12769163 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16099715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20067609 — Biomarker: TGFB1
Type: Safety Biomarker (SAF)
Genes: CED; TGFbeta
Study 21945258 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study 11896424 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11896424 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 3178370 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16035956 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12514674 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17963865 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 15987488 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 15987488 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 2545454 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2545454 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8345497 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 3453186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27091810 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22108774 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 22108774 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 15516364 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 14533141 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31051056 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 11113721 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24838809 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 24838809 — Biomarker: SGCA mRNA
Type: Predictive Biomarker (PRD)
Genes: SGCA; ADL; DAG2
Study 10430348 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 22643131 — Biomarker: SLC12A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC12A2; NKCC1
Study 9503102 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25948437 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18946064 — Biomarker: CD52 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD52; CDW52; HE5
Study 8986493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2172535 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 30957213 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 11588409 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11588409 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11588409 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9632325 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 2574084 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 31533093 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26468478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8269183 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 8269183 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2994988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25925484 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23049590 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 14624393 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14624393 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8260371 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 25436661 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 20732526 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 20732526 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20732526 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 16192766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12814476 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10385641 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 10385641 — Biomarker: RNASE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RNASE2; EDN; RNS2
Study 11818522 — Biomarker: Fatty acid amide hydrolase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: FAAH; FAAH1
Study 2117147 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 26204331 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 26204331 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23709289 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11253161 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11253161 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9200286 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 30993861 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 9630109 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 28407408 — Biomarker: FMR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMR1
Study 12894480 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 8508009 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24728578 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24728578 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 20185595 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 20185595 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28760693 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 27237598 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21691934 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 17356308 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 8125421 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8125421 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23848184 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9814449 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9814449 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2574045 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18380771 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18380771 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 14620923 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14620923 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8630662 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8630662 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16317760 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 9140705 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23951825 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 21914162 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10354218 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10354218 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8877260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8877260 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7113575 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8834645 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 24440167 — Biomarker: LTB mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB; TNFC; TNFSF3
Study 24440167 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16389742 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 9052903 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8306902 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21593349 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16965910 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 16965910 — Biomarker: Cyclin-dependent kinase inhibitor 1
Type: Safety Biomarker (SAF)
Genes: CDKN1A
Study 16965910 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 10899363 — Biomarker: AMPH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMPH; AMPH1
Study 29329233 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 29329233 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 21354549 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)