AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31364286 — Biomarker: COL4A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL4A3
Study 31364286 — Biomarker: COL4A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL4A4
Study 31364286 — Biomarker: COL4A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL4A5
Study 31364286 — Biomarker: NPHS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NPHS1; NPHN
Study 31364286 — Biomarker: EYA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EYA1
Study 31364286 — Biomarker: CLCN5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLCN5; CLCK2
Study 31364286 — Biomarker: LAMC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMC1; LAMB2
Study 27085434 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 22219414 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20432816 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20432816 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17980248 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17980248 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15063404 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16750985 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11081782 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11081782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30823944 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 30823944 — Biomarker: Th2 cell
Type: Safety Biomarker (SAF)
Study 25852208 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15189958 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15189958 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 2551397 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 31441419 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31441419 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 31441419 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25175554 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 23908318 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23908318 — Biomarker: TNFRSF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1A; TNFAR; TNFR1
Study 23908318 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 11551575 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8330828 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30250241 — Biomarker: GHR mRNA
Type: Predictive Biomarker (PRD)
Genes: GHR
Study 30250241 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 30250241 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 30250241 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 12944209 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 12944209 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12944209 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27930408 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21455087 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8259746 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25760277 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 23551956 — Biomarker: MAOB mRNA
Type: Predictive Biomarker (PRD)
Genes: MAOB
Study 10673512 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8862237 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6394516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18502109 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18502109 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 6138009 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 25413313 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 15179210 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31226721 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 22460183 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3706373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15897362 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15897362 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14570950 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27724992 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 23597332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16800987 — Biomarker: GCA mRNA
Type: Predictive Biomarker (PRD)
Genes: GCA; GCL
Study 28056202 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15540688 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11583866 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 18445674 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 24891317 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26083408 — Biomarker: RRAD mRNA
Type: Predictive Biomarker (PRD)
Genes: RRAD; RAD
Study 23816410 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19434235 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25810849 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11454885 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11454885 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 11454885 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 7921311 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 31608934 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 24942170 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 10389775 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11791035 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7470518 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31654268 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 24413845 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 9667603 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 8208596 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23298603 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 20839290 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26211411 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 7963709 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 31772064 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26654101 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 18419825 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14984503 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 14984503 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 14984503 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2868657 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16507515 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 16507515 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 8291370 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 31096162 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21220480 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 21220480 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 21220480 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28323947 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 20177421 — Biomarker: AOX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AOX1; AO
Study 17044952 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 14578921 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21712736 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21712736 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 21712736 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7814158 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22869943 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 31240388 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26025630 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22947355 — Biomarker: CYP11B1 mRNA
Type: Safety Biomarker (SAF)
Genes: CYP11B1; S11BH
Study 2274431 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28703124 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 28703124 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 28703124 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20670096 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15327190 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2975554 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 31433717 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 22382665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31074005 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 15225149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21739234 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 9178340 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 9178340 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26959652 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11874387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6136936 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31892489 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31892489 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23511299 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23511299 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 30170781 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30170781 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30170781 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25809236 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 25809236 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 21751435 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31486158 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31486158 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22082677 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22082677 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 20538833 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 20538833 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12915697 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 22315948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7506675 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 7506675 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2574766 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2574766 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26156625 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26156625 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21971374 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9226735 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 29059139 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 18327010 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11044230 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11044230 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27779461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12398965 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12398965 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 7752918 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27292104 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study 22300739 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 22300739 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 19543205 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 31838924 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 25898203 — Biomarker: GARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GARS1; GARS
Study 19786221 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 9199118 — Biomarker: DBH mRNA
Type: Predictive Biomarker (PRD)
Genes: DBH
Study 9199118 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 9199118 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1672698 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1672698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18981951 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17244766 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 12428688 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 23178794 — Biomarker: Mothers against decapentaplegic homolog 2
Type: Predictive Biomarker (PRD)
Genes: SMAD2; MADH2; MADR2
Study 23178794 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 23178794 — Biomarker: SOCS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOCS3; CIS3; SSI3
Study 9950098 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28716357 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11006427 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 11006427 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 11006427 — Biomarker: Serum antibody concentration
Type: Surrogate Endpoint (SUR)
Study 9206240 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 6692650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22318394 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 14985677 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22735866 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17653691 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 15774493 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10405985 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10405985 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24290960 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22658931 — Biomarker: SPSB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPSB1; SSB1
Study 22658931 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 11988933 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 28219610 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23289969 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 23289969 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 10954887 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20979731 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 18832293 — Biomarker: AKR1C1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKR1C1; DDH; DDH1
Study 18832293 — Biomarker: AKR1C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKR1C2; DDH2
Study 18832293 — Biomarker: AKR1C3 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKR1C3; DDH1; HSD17B5; KIAA0119; PGFS
Study 12934402 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 6298047 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 22959886 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22959886 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22959886 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22959886 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 17446340 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17446340 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17446340 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9756554 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9756554 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 9756554 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 26725391 — Biomarker: PLIN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLIN1; PERI; PLIN
Study 26725391 — Biomarker: PLIN4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PLIN4; KIAA1881
Study 8867395 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8867395 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24255061 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 24255061 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22894911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12842237 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2060564 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2060564 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16091635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29535047 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 27548212 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24724616 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 24724616 — Biomarker: ANKK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANKK1; PKK2; SGK288
Study 24724616 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 22012257 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 22012257 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10