AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24711067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7836734 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24675911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29457538 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25319187 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25319187 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 20403637 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 2187002 — Biomarker: DIAPH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DIAPH2; DIA
Study 30500981 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28972083 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11766084 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18443762 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8782754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1352363 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6424580 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30173303 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 31434390 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 31434390 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7872170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26083546 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21592994 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21592994 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21592994 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 21592994 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21592994 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21592994 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21592994 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 21592994 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 15007110 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9868115 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2904757 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2904757 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27228002 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 21716297 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17134628 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 25164709 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 20191258 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18400837 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 12584669 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12584669 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28653377 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28653377 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 26362831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23232993 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23232993 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11110875 — Biomarker: PDXP mRNA
Type: Predictive Biomarker (PRD)
Genes: PDXP; CIN; PLP; PLPP
Study 29067834 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10781481 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8635674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1425867 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 9017770 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8300456 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30681971 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30681971 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28659346 — Biomarker: AMY1A mRNA
Type: Predictive Biomarker (PRD)
Genes: AMY1A; AMY1
Study 20104985 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 11865364 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 17077058 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 25840952 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12631177 — Biomarker: MAEA mRNA
Type: Predictive Biomarker (PRD)
Genes: MAEA; EMP; HLC10; PIG5
Study 11085964 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1352732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15041568 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11719730 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 9322139 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8432299 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30617247 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16406721 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 12922956 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31504608 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30133134 — Biomarker: ABHD14B mRNA
Type: Predictive Biomarker (PRD)
Genes: ABHD14B; CIB
Study 25129333 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20605898 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 10225243 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10225243 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 1693732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23446733 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 23446733 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 3259087 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31885286 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 22858559 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 10788542 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23901264 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14610048 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 16468060 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16468060 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 1478035 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 29506562 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26599983 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 16463837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24856748 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22562540 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22562540 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12421195 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 12421195 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12421195 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12421195 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 25761503 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 21415357 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 26952590 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23396551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20061429 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20061429 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 20061429 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20061429 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11994349 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 9705044 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 688256 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31324214 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 23456731 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23456731 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11888226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 353464 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 21932579 — Biomarker: OMD mRNA
Type: Predictive Biomarker (PRD)
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 11566454 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 11566454 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29071556 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29071556 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29071556 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 29071556 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27784336 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 27784336 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 27784336 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26084979 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7949636 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 28121915 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19346845 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 11743460 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21939972 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21939972 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21939972 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 21939972 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 21939972 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 18312071 — Biomarker: Fibroblast growth factor 1
Type: Safety Biomarker (SAF)
Genes: FGF1
Study 6666215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31615840 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 30223252 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 25653511 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8641482 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 23219537 — Biomarker: SEPTIN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEPTIN3; SEP3; SEPT3
Study 23219537 — Biomarker: SEPTIN6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEPTIN6; KIAA0128; SEP2; SEPT6
Study 19081791 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9058683 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28654629 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16254428 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 14605511 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14605511 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21165861 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10414418 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2129490 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 27486122 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9846847 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9846847 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1060744 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 1060744 — Biomarker: POMP mRNA
Type: Predictive Biomarker (PRD)
Genes: POMP; C13orf12; UMP1; HSPC014; HSPC036; PNAS-110
Study 30637662 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29774682 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 23452344 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 7646097 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10671187 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 21054754 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 19145785 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2606855 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30649238 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23271170 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26305528 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 26305528 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 26305528 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 26305528 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 9556010 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31154664 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18285545 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18285545 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9080244 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3472450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30688673 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 19946034 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 19946034 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 10501652 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 30286300 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30286300 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 30286300 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12939852 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3296637 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 24851679 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18622504 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12451430 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 12451430 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 8938548 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 1752602 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 22772951 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 9443770 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9443770 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27520090 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20877623 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 14510719 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 14510719 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 30017407 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 30017407 — Biomarker: WAP four-disulfide core domain protein 2
Type: Predictive Biomarker (PRD)
Genes: WFDC2; HE4; WAP5
Study 19126248 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29991034 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 27681865 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 27681865 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 27681865 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 27681865 — Biomarker: NOTCH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOTCH1; TAN1
Study 27681865 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 12740532 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10994885 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 30470592 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 19837920 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 30655198 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 26717354 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 26717354 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 24050803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20574413 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 20574413 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17967602 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8432776 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 8432776 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29212825 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24827969 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study 26343552 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 31720257 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31720257 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31720257 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31720257 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12184060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6753911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28712074 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 28712074 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30446894 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 18652757 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17068384 — Biomarker: CDCA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDCA3; C8; GRCC8; TOME1
Study 12664247 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10560170 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 27163519 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21459785 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18089701 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16929710 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67