AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 14673985 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29102571 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 22295826 — Biomarker: REST mRNA
Type: Predictive Biomarker (PRD)
Genes: REST; NRSF; XBR
Study 10190653 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10190653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19101227 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19101227 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9669009 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17199098 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 9138543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8709213 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22535269 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19433070 — Biomarker: CPOX mRNA
Type: Predictive Biomarker (PRD)
Genes: CPOX; CPO; CPX
Study 26547109 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 11001892 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 6141051 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6141051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27375066 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 17659942 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11861267 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 31831574 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22875659 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15333723 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30613999 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21747002 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 28743247 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26158573 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 7575710 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 7575710 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 16052108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19793378 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 2818394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 46963 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25577471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21726916 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14559317 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14559317 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10812331 — Biomarker: CPD mRNA
Type: Predictive Biomarker (PRD)
Genes: CPD
Study 1509401 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1509401 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 1962599 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 26651453 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19680279 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 16421365 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30102965 — Biomarker: FGFR1
Type: Predictive Biomarker (PRD)
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 24901463 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10698385 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 17490928 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11833827 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11833827 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8625624 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 24135509 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 23901023 — Biomarker: S100A12 mRNA
Type: Predictive Biomarker (PRD)
Genes: S100A12
Study 23901023 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 23901023 — Biomarker: ADAM10 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM10; KUZ; MADM
Study 20948453 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 18303408 — Biomarker: Plasma DNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25024070 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22967970 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 22967970 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 22967970 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 1693173 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25801761 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 23480506 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 23480506 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26043651 — Biomarker: FST mRNA
Type: Predictive Biomarker (PRD)
Genes: FST
Study 12209517 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 12209517 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12209517 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16869933 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2053453 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26930571 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15896247 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 31486004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16634952 — Biomarker: CPE mRNA
Type: Predictive Biomarker (PRD)
Genes: CPE
Study 16634952 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12632341 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 31869430 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 31869430 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 27733219 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 24534763 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18564806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10957661 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 6383692 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18503492 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17687925 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 11673813 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29405635 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20392617 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 20392617 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20392617 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 19346113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19346113 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19346113 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19346113 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24267040 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17577103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31605113 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 27756788 — Biomarker: TNFRSF9 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF9; CD137; ILA
Study 12742981 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 12742981 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10694896 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29524621 — Biomarker: SIGLEC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIGLEC1; SN
Study 24446590 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24446590 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9625686 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9509822 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 4054138 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26852290 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 26852290 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20438539 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 2013178 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 29203355 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 9186538 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2418302 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21570659 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 18812844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17181880 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 12709722 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 20377476 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21133303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22470539 — Biomarker: NANOS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS3; NOS3
Study 10839585 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9175045 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3921124 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2853194 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 26289682 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 21936956 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21936956 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 21936956 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25644388 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 25644388 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25644388 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9292253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29166130 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 27190009 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 27190009 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 20375907 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8733877 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 1706531 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 21798863 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 16964364 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9394314 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9312762 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9312762 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 9312762 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 9312762 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 7589029 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 24398649 — Biomarker: STAT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT4
Study 22568596 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19710188 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 802071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26529159 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21809439 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 21809439 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21809439 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8755685 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1389702 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29678772 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29678772 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27126487 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25159234 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22479327 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 22479327 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 28338180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24167370 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 12577420 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 9264433 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8221271 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 29663363 — Biomarker: TAFA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAFA4; FAM19A4
Study 18662629 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 30586113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30586113 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30586113 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 30586113 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23139215 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 23139215 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 23139215 — Biomarker: SIGIRR mRNA
Type: Predictive Biomarker (PRD)
Genes: SIGIRR; UNQ301/PRO342
Study 18386615 — Biomarker: DDT mRNA
Type: Predictive Biomarker (PRD)
Genes: DDT
Study 18386615 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18386615 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 6222710 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 6222710 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27457968 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24468081 — Biomarker: PAG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAG1; CBP; PAG
Study 11008920 — Biomarker: CYP1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A1
Study 11008920 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 23430667 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18029165 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 10800878 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30579763 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 27825009 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21180275 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22029980 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 11598313 — Biomarker: Neuromodulin
Type: Pharmacodynamic Biomarker (PDY)
Genes: GAP43
Study 21968267 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 16864930 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9416409 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 21041815 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 2636645 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24817417 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20298399 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16621879 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1937993 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30607616 — Biomarker: CAMP mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMP; CAP18; FALL39; HSD26
Study 11789275 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 11789275 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 1312233 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 1312233 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24637789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10344365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7047170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21946121 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 10052667 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 10052667 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 26585118 — Biomarker: 2-hydroxyglutarate
Type: Pharmacodynamic Biomarker (PDY)
Study 8141177 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31047956 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25468387 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 25468387 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 20957342 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16912060 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 26270341 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 11023927 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10677983 — Biomarker: IL17RD mRNA
Type: Predictive Biomarker (PRD)
Genes: IL17RD; IL17RLM; SEF; UNQ6115/PRO20026
Study 10677983 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 7699214 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24782115 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 19957031 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12957441 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 12957441 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12957441 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12957441 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 29193350 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29193350 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27508851 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15673390 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10549839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8524727 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8524727 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1837120 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7073460 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27737408 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 22708952 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28452620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19308439 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)