AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 29929537 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1333781 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27452372 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22121923 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 19723695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9667263 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 8138256 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 24570387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7015797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8497553 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30790724 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 24521695 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 20653608 — Biomarker: FOXO3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXO3; FKHRL1; FOXO3A
Study 16710858 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16710858 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15273831 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 25780462 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10438709 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 10438709 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 17559729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15613407 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15613407 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 15613407 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 15613407 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 15613407 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10101627 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19670975 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17443369 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 17443369 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24619865 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14557561 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 8631039 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1687407 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30497093 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 14984727 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14984727 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 14984727 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11590517 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30945740 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23190794 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23190794 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 1740938 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 23713245 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15185466 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12047395 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12047395 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8172113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29082824 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 29082824 — Biomarker: MZB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MZB1; MEDA7; PACAP; HSPC190
Study 17375982 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 17375982 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17375982 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 16045526 — Biomarker: MEA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MEA1; MEA
Study 7788826 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25714016 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 9176645 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8222166 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8222166 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2871333 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20624511 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16036503 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 12585170 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9312759 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 25006770 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 12777952 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 12777952 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9843104 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9843104 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3517250 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 29908669 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29908669 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 26527782 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 26135348 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14578367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11445478 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 19900054 — Biomarker: LARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LARS1; KIAA1352; LARS
Study 15570922 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 9311544 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28938325 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 23797810 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 20820174 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 28159703 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 21601197 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21601197 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19751797 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 19751797 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 12661911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1363508 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 1363508 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 25499341 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 1899852 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 30252057 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 29176264 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19066934 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 19066934 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 17909376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10980585 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27845859 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12859696 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12859696 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9352040 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26179891 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12142559 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11981006 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10386509 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10386509 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21775558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9416721 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8495702 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30035621 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26142300 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 12655445 — Biomarker: Plasma methotrexate
Type: Surrogate Endpoint (SUR)
Study 11078293 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 1596307 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29489895 — Biomarker: Auditory steady-state response
Type: Pharmacodynamic Biomarker (PDY)
Study 27009101 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 17980884 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 17980884 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 16226024 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 16226024 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7480566 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30835152 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 19724023 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19724023 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8402658 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 8684872 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 1516602 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 6408669 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 24845183 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18029338 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21749017 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1763796 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 6130077 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 23197976 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23197976 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 16806875 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9871843 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 2398244 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 24389597 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 12110024 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 8998247 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15385735 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29244528 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29244528 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29244528 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 26630680 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 19026303 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19026303 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19026303 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16140027 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 31754882 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 25249405 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25249405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25249405 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21263343 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11479164 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20010618 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9240887 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 31529406 — Biomarker: TNFSF13 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 19633827 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8491068 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7785682 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31882564 — Biomarker: DLGAP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DLGAP2
Study 15133343 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 26599219 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 26599219 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26599219 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 22371898 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17355729 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 17355729 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 10521382 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 20454993 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 17363405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10226245 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31496244 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 28321001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26445302 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21538174 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10524688 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 24300751 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22705428 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15842138 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15842138 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15842138 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 15842138 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12578487 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18400939 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18400939 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8567042 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22925832 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22925832 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15568149 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 15568149 — Biomarker: TET1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET1; CXXC6; KIAA1676; LCX
Study 7527327 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 31659803 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 29868915 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29868915 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24056269 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20739447 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18288087 — Biomarker: PDE4D mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE4D; DPDE3
Study 18288087 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23379539 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 23379539 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 22204724 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19367154 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15247960 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15247960 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 30717153 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 30717153 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 25961136 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22613418 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 11861354 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 28575534 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 28575534 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28575534 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 19376321 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 24727254 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24727254 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18565801 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11919122 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 11919122 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2035280 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 7038858 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 31276165 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 27559855 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8877075 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8877075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31146701 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26251312 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17493194 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12099976 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14602361 — Biomarker: SLC10A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC10A3; DXS253E; P3
Study 24879494 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 24879494 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16280447 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12123334 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11498911 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9691864 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 9691864 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 29231344 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26231378 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14623801 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 14623801 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 1424413 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 11420782 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27287612 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD