AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 30371283 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 23612435 — Biomarker: OPRD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OPRD1; OPRD
Study 16488335 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12422907 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7724390 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26791678 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 26791678 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26791678 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 18375896 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18375896 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 16683008 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 30352580 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27220960 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 27220960 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27220960 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 27220960 — Biomarker: VEGFC mRNA
Type: Predictive Biomarker (PRD)
Genes: VEGFC
Study 27220960 — Biomarker: EPGN mRNA
Type: Predictive Biomarker (PRD)
Genes: EPGN; UNQ3072/PRO9904
Study 22524549 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 19937133 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 19937133 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 15711353 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 1484945 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1484945 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14551237 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14551237 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27151222 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 19678756 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19678756 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19678756 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19390223 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19390223 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 29921161 — Biomarker: PCSK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK5; PC5; PC6
Study 24934276 — Biomarker: ORMDL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ORMDL3
Study 24934276 — Biomarker: GSDMB mRNA
Type: Predictive Biomarker (PRD)
Genes: GSDMB; GSDML; PP4052; PRO2521
Study 24934276 — Biomarker: FADS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS2
Study 24934276 — Biomarker: F13A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: F13A1; F13A
Study 7560599 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 25994603 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21640424 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15040544 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9713731 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9713731 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 9713731 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 18305079 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11319567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11319567 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21652220 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 21652220 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17554581 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12584837 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24289591 — Biomarker: REG3A mRNA
Type: Predictive Biomarker (PRD)
Genes: REG3A; HIP; PAP; PAP1
Study 3555898 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 17199580 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2547560 — Biomarker: TAC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAC1; NKA; NKNA; TAC2
Study 23794107 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 21183746 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 31876643 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10506601 — Biomarker: AFM mRNA
Type: Predictive Biomarker (PRD)
Genes: AFM; ALB2; ALBA
Study 10506601 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 10506601 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 1855763 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1855763 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27069360 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27069360 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25304727 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 22789797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22789797 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15499224 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 15499224 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 15499224 — Biomarker: Plasma testosterone level
Type: Surrogate Endpoint (SUR)
Study 21693699 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21693699 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21693699 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18300746 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 18300746 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 16608780 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 14600575 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14600575 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8782296 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 31903773 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31903773 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 21031578 — Biomarker: SGCA mRNA
Type: Predictive Biomarker (PRD)
Genes: SGCA; ADL; DAG2
Study 21031578 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 12368364 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 322921 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24704626 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 24704626 — Biomarker: APOA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOA1
Study 24704626 — Biomarker: Apolipoprotein C-II
Type: Monitoring Biomarker (MOI)
Genes: APOC2; APC2
Study 24704626 — Biomarker: APOB mRNA
Type: Predictive Biomarker (PRD)
Genes: APOB
Study 24704626 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12814810 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8973752 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 30229683 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 30229683 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 20038730 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 11804991 — Biomarker: ELK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELK3; NET; SAP2
Study 11804991 — Biomarker: NE
Type: Predictive Biomarker (PRD)
Study 11804991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8566936 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8566936 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2884856 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12218723 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9468457 — Biomarker: CPA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA6; CPAH
Study 9468457 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11171824 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 18035193 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16303729 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9527194 — Biomarker: GRAMD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRAMD4; DIP; KIAA0767
Study 30879908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28399624 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 28399624 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11271083 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 31470599 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28449232 — Biomarker: SARM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARM1; KIAA0524; SAMD2; SARM
Study 26381232 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 21723443 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21723443 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21723443 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20017932 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2839628 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2839628 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31870692 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 15254884 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15254884 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7944835 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30352838 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 25248814 — Biomarker: IGFBP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP7; MAC25; PSF
Study 19883392 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19883392 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19883392 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16118090 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 16118090 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20212029 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17392142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12488154 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 2141494 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 30398382 — Biomarker: RRAD mRNA
Type: Predictive Biomarker (PRD)
Genes: RRAD; RAD
Study 24209894 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 24209894 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 24209894 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 20881877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15390214 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 20844543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17715031 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16042670 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 30965389 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 22207676 — Biomarker: ACKR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACKR1; DARC; FY; GPD
Study 15889519 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12364422 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12658930 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 20618675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10519433 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7195230 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30921340 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30921340 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18611341 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 25338198 — Biomarker: CD79A mRNA
Type: Predictive Biomarker (PRD)
Genes: CD79A; IGA; MB1
Study 15488878 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 15488878 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 3276279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31657167 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 25413223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25413223 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11113718 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29529169 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29529169 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 23190359 — Biomarker: PROCR mRNA
Type: Predictive Biomarker (PRD)
Genes: PROCR; EPCR
Study 12709682 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12709682 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 8793451 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 6388897 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6388897 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8743516 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8743516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1656826 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1656826 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29261566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25480930 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31299655 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25904586 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 25904586 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 25904586 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23552179 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16100235 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25074283 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 19732445 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2216994 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26577455 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 15668637 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 27258567 — Biomarker: NKX2-1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NKX2-1; NKX2A; TITF1; TTF1
Study 18936475 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18936475 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 14518526 — Biomarker: PCLO mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLO; ACZ; KIAA0559
Study 29112461 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28290847 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21058198 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15660667 — Biomarker: RGS4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RGS4
Study 25671766 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19447425 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 25873370 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 21296768 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8154167 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 6123330 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 6758746 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29516853 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 15637138 — Biomarker: STIL mRNA
Type: Predictive Biomarker (PRD)
Genes: STIL; SIL
Study 15637138 — Biomarker: TAL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAL1; BHLHA17; SCL; TCL5
Study 15637138 — Biomarker: PICALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PICALM; CALM
Study 15637138 — Biomarker: MLLT10 mRNA
Type: Predictive Biomarker (PRD)
Genes: MLLT10; AF10
Study 15637138 — Biomarker: TLX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLX1; HOX11; TCL3
Study 15637138 — Biomarker: TLX3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLX3; HOX11L2
Study 12236426 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21604824 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 19444092 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17584199 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 29030456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18495694 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 14561241 — Biomarker: NANOS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS3; NOS3
Study 14561241 — Biomarker: CYBA mRNA
Type: Predictive Biomarker (PRD)
Genes: CYBA
Study 9122287 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 9122287 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26019334 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 22030228 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22030228 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10714858 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10714858 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10516448 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 10516448 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 8818434 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1408685 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 1408685 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 1408685 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31029534 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 24226057 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1545080 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1545080 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 30254071 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 22231041 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2271366 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21357275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21357275 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 17335962 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study 14764129 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 3311054 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23566943 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20931100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8846291 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)