AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 20533245 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20533245 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18240282 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18240282 — Biomarker: FOXP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 12828793 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12828793 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10751234 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24240315 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 16154486 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21608215 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21608215 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 21608215 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23041990 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 23041990 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 16153509 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 27312989 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 11329107 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8673477 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 31689748 — Biomarker: PERP mRNA
Type: Predictive Biomarker (PRD)
Genes: PERP; KCP1; KRTCAP1; PIGPC1; THW
Study 31689748 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 23797608 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 11449079 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9683204 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28224926 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18929284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16470820 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 11604980 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18796620 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18796620 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 18796620 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10433305 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7717819 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 7717819 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7717819 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28682422 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 25932899 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 25932899 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25932899 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17515464 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11275935 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11275935 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9666011 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9666011 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 24016864 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15191344 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15191344 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 15191344 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 15191344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9233740 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9233740 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8423228 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 28067719 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 28067719 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 30348101 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 30348101 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 20881283 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19031508 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 19031508 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10425010 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 19417610 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19417610 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19417610 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 19417610 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 19417610 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 29380956 — Biomarker: FADD mRNA
Type: Predictive Biomarker (PRD)
Genes: FADD; MORT1; GIG3
Study 29380956 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 29380956 — Biomarker: BAD mRNA
Type: Predictive Biomarker (PRD)
Genes: BAD; BBC6; BCL2L8
Study 29380956 — Biomarker: CASP9
Type: Predictive Biomarker (PRD)
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 23292674 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 10502079 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10502079 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 12915593 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24938562 — Biomarker: GNAQ mRNA
Type: Predictive Biomarker (PRD)
Genes: GNAQ; GAQ
Study 24938562 — Biomarker: MAP2K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K1; MEK1; PRKMK1
Study 24938562 — Biomarker: MAP2K2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K2; MEK2; MKK2; PRKMK2
Study 23136545 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 10483952 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8963892 — Biomarker: SHD mRNA
Type: Predictive Biomarker (PRD)
Genes: SHD
Study 8963892 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12544868 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 16734607 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24755339 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 18004285 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 2189551 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 25912560 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19129278 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19129278 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17285888 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 14583440 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 10682134 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2492741 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30455077 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 11923809 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9934939 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 2110575 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 19939874 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 7948449 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 7948449 — Biomarker: PTK7 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTK7; CCK4
Study 7948449 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24076594 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24076594 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24076594 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 16009883 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 8603942 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 22065199 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 24687927 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 7000243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23672349 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 23672349 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 29752869 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 22913889 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22913889 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7846197 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3132360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23289728 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 12952249 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12952249 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 12952249 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 1576067 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 1576067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11439738 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8458096 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10754428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27756097 — Biomarker: ME1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ME1
Study 26764966 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 22847212 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22847212 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22847212 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28115830 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 25697431 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19406886 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12686336 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8905804 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 20720259 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 12182251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8974212 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23589565 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9175967 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 4014015 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30925958 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30925958 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30925958 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30925958 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17414346 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9871930 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 27030648 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 24886225 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15724142 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 15724142 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 10645192 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30765407 — Biomarker: LSS mRNA
Type: Predictive Biomarker (PRD)
Genes: LSS; OSC
Study 10840537 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10840537 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31764468 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12145009 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 12145009 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 19675744 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19675744 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17170202 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 11470011 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4051323 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19295225 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 16886936 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 11740417 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 11740417 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 11740417 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 11740417 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20395857 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 20395857 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 8735778 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 7038076 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30909877 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30909877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24245880 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 22955227 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19838098 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19838098 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25647646 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 23339726 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23339726 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23339726 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 21401585 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 22494856 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 20236216 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 17916949 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15613422 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10404946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28472315 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6962709 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6962709 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12047481 — Biomarker: PGP mRNA
Type: Predictive Biomarker (PRD)
Genes: PGP
Study 1703602 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26261902 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 20437580 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20437580 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20437580 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 20437580 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 31045465 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25853236 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21290145 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 21290145 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 8607394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2006246 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 26324089 — Biomarker: HNF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: HNF1A; TCF1
Study 23151017 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21873490 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 18294116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18294116 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15293527 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3319637 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27245928 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20360753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15998652 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 19345451 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 19345451 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 14981006 — Biomarker: EDNRA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDNRA; ETA; ETRA
Study 3133924 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22018299 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 8736266 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30165858 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30165858 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 30165858 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 30165858 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10389286 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7035184 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29045610 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 24678280 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24678280 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 24678280 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12084522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7867870 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17093179 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 27195814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15683479 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 12586452 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 16586308 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 7491881 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 16998094 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12151034 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 12151034 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 23768612 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 22439807 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22439807 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22439807 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)