AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 21752726 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12798881 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 1475511 — Biomarker: KCNN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNN1; SK
Study 6383615 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6383615 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 27491226 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18574391 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 18574391 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 18574391 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 18574391 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 20453626 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 20453626 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29262841 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26427627 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 8989740 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26733011 — Biomarker: Nuclear factor erythroid 2-related factor 2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: NFE2L2; NRF2
Study 17429836 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 17429836 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 16338283 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 12380231 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 28449368 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 21225090 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21225090 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8844442 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1321198 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23661492 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24423369 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 14632678 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 9197949 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 15889392 — Biomarker: Vitamin K-dependent protein C
Type: Safety Biomarker (SAF)
Genes: PROC
Study 11938860 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 3426824 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 25257752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25346595 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15087294 — Biomarker: Histone acetylation
Type: Pharmacodynamic Biomarker (PDY)
Study 15087294 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15087294 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15087294 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 9309457 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 20164363 — Biomarker: APOA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOA1
Study 20164363 — Biomarker: Apolipoprotein A-IV
Type: Monitoring Biomarker (MOI)
Genes: APOA4
Study 18682511 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27722092 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 12766967 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10631440 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2256719 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 25284266 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15673408 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 26073353 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22089106 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9010697 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 18502300 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12972476 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31660706 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 31660706 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 31660706 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 27571889 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 23312069 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 23312069 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 15286547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29543566 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29543566 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 15585311 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15585311 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 8689881 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 30866943 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 25577869 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 25577869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25577869 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 21295843 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 17686164 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 3428346 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8860097 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1512524 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 1512524 — Biomarker: TBX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TBX2
Study 30803503 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30803503 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25823387 — Biomarker: TEF mRNA
Type: Predictive Biomarker (PRD)
Genes: TEF; KIAA1655
Study 10648311 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8712329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29300100 — Biomarker: PICALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PICALM; CALM
Study 29300100 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 24169242 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21915866 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18249219 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 18249219 — Biomarker: ADRB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB3; ADRB3R; B3AR
Study 18249219 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18249219 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18249219 — Biomarker: IGF1R mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1R
Study 18249219 — Biomarker: LIPC mRNA
Type: Predictive Biomarker (PRD)
Genes: LIPC; HTGL
Study 18249219 — Biomarker: LEPROT mRNA
Type: Predictive Biomarker (PRD)
Genes: LEPROT; LEPR; OBR
Study 11128360 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11128360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31146772 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 31146772 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 28032641 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 26444022 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 23660094 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23660094 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23660094 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23660094 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 17350370 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21725053 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 21725053 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 12638099 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 23503652 — Biomarker: E2F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: E2F3; KIAA0075
Study 23503652 — Biomarker: miR-125b
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20600025 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 8874257 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15310639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11781224 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 28911141 — Biomarker: FOXO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXO1; FKHR; FOXO1A
Study 23638898 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 21195942 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30530462 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17336254 — Biomarker: PAFAH1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study 8726096 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6795915 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28045958 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 17358099 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9809620 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 20561878 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19231245 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2728827 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24672937 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15959616 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 214866 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22703536 — Biomarker: CPE mRNA
Type: Predictive Biomarker (PRD)
Genes: CPE
Study 26039911 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26039911 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 26039911 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 19065655 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 19065655 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 23221984 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23221984 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 19712983 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17848804 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC
Study 17848804 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 17848804 — Biomarker: C-C motif chemokine 4
Type: Monitoring Biomarker (MOI)
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 17848804 — Biomarker: Th2 cell
Type: Safety Biomarker (SAF)
Study 6794075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29030692 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15990669 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 15990669 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 21540202 — Biomarker: MAF mRNA
Type: Predictive Biomarker (PRD)
Genes: MAF
Study 14729239 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2649864 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 17873305 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11518846 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22134388 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30206618 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27690741 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 27690741 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 14668709 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6308996 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6308996 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30454724 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 30615489 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30615489 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 21733988 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21733988 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 17089153 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 12215207 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12215207 — Biomarker: Mitochondrial membrane potential
Type: Pharmacodynamic Biomarker (PDY)
Study 10786501 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 27480383 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 23926586 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 23926586 — Biomarker: FGG mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGG; PRO2061
Study 21068351 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26321469 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 26321469 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 25168637 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21029014 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10619581 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10619581 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31125701 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25546556 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 11516602 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31003735 — Biomarker: PPP3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPP3CA; CALNA; CNA
Study 9346997 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 3098950 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 30345850 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24050764 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 24050764 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18083065 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 2045530 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 2045530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24907403 — Biomarker: DSP mRNA
Type: Predictive Biomarker (PRD)
Genes: DSP
Study 9192239 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26231133 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8878342 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 1447078 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1447078 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 24038028 — Biomarker: APAF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APAF1; KIAA0413
Study 24038028 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 24038028 — Biomarker: BAD mRNA
Type: Predictive Biomarker (PRD)
Genes: BAD; BBC6; BCL2L8
Study 24038028 — Biomarker: Induced myeloid leukemia cell differentiation protein Mcl-1
Type: Predictive Biomarker (PRD)
Genes: MCL1; BCL2L3
Study 24038028 — Biomarker: XIAP mRNA
Type: Predictive Biomarker (PRD)
Genes: XIAP; API3; BIRC4; IAP3
Study 24038028 — Biomarker: BCL2L1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCL2L1; BCL2L; BCLX
Study 24038028 — Biomarker: ENDOG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENDOG
Study 24038028 — Biomarker: YWHAB mRNA
Type: Predictive Biomarker (PRD)
Genes: YWHAB
Study 24038028 — Biomarker: YWHAQ mRNA
Type: Predictive Biomarker (PRD)
Genes: YWHAQ
Study 20028946 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1330434 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 25262260 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 10980827 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7669490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7026073 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 19278844 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19278844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31092142 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 26374448 — Biomarker: ADIPOQ mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 22269592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10690132 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21704242 — Biomarker: SLC38A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC38A3; G17; NAT1; SN1; SNAT3
Study 21704242 — Biomarker: SLC38A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 21704242 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19428083 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 19428083 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 15948098 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 12841537 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 2693691 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 12426514 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 12426514 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 12426514 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 30471795 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 30471795 — Biomarker: TLR6 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR6
Study 30471795 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 30471795 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 11096166 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31726485 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28137609 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28137609 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8336864 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3528119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21050796 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16596114 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 16596114 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16596114 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 12575402 — Biomarker: SKI mRNA
Type: Predictive Biomarker (PRD)
Genes: SKI
Study 29119483 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 24600214 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20435291 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20435291 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20435291 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11046211 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)