AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT02147002 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04061382 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT02225509 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study NCT02225509 — Biomarker: 14-3-3 protein sigma
Type: Predictive Biomarker (PRD)
Genes: SFN; HME1
Study NCT03812263 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study NCT03812263 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study NCT03812263 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT03512990 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study NCT00002719 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01037166 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT01919879 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00121173 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study NCT00721266 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00721266 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT00781508 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study NCT03908073 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01407822 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01543737 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT03851679 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study NCT02401256 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study NCT03110744 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study NCT03110744 — Biomarker: CDKN2A mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2A; CDKN2; MTS1
Study NCT01165203 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT03303885 — Biomarker: SDC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SDC1; SDC
Study NCT03303885 — Biomarker: FGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF2; FGFB
Study NCT03303885 — Biomarker: FGF18 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF18; UNQ420/PRO856
Study NCT05913557 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03531034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03997539 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02105766 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT00389506 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study NCT00498862 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03768921 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00654485 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03313505 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study NCT04329975 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study NCT04574427 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT02005133 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00508586 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00508586 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT02234934 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT04223648 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03486431 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study NCT02188121 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03640767 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02739984 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03742492 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00717353 — Biomarker: UGT2B7 mRNA
Type: Predictive Biomarker (PRD)
Genes: UGT2B7; UGTB2B9
Study NCT01616303 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study NCT01437878 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study NCT02044471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04341844 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study NCT04497246 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT03558932 — Biomarker: PKM mRNA
Type: Predictive Biomarker (PRD)
Genes: PKM; OIP3; PK2; PK3; PKM2
Study NCT05007171 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT04664244 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04664244 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00988169 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02154269 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01428011 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01708083 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT01429012 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT02826135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00974883 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00198159 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00198159 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT01892527 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01892527 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT01892527 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT02874651 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02874651 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT03732222 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study NCT03732222 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT04035122 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00686179 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study NCT03349333 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT04121416 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01087203 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study NCT01387373 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00829166 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00829166 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT01119560 — Biomarker: MYCN mRNA
Type: Predictive Biomarker (PRD)
Genes: MYCN; BHLHE37; NMYC
Study NCT04471597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00101309 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT00718861 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00186329 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study NCT00666874 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03505697 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT01183416 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00461266 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT02333240 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00858702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02143518 — Biomarker: TLR9
Type: Predictive Biomarker (PRD)
Genes: CD289
Study NCT01654081 — Biomarker: ISG15 mRNA
Type: Predictive Biomarker (PRD)
Genes: ISG15; G1P2; UCRP
Study NCT01136226 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study NCT04515927 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study NCT01583582 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT01583582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02538666 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT03743428 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03043963 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04641481 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT01167920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00337298 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04095390 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04095390 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study NCT00362037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00395096 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study NCT02717221 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02430363 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study NCT02909166 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study NCT02020603 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study NCT05712967 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study NCT02398396 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study NCT04286399 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study NCT00628914 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT01934998 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study NCT03139097 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01266707 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT01266707 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study NCT01266707 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT04452812 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT00291278 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00204126 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT04130152 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT04130152 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04130152 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT04130152 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03828838 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01377363 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01756300 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03230253 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT03230253 — Biomarker: ASPSCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study NCT03230253 — Biomarker: ZMYM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZMYM2; FIM; RAMP; ZNF198
Study NCT03230253 — Biomarker: Platelet-derived growth factor B
Type: Pharmacodynamic Biomarker (PDY)
Genes: PDGFB; PDGF2; SIS
Study NCT02951546 — Biomarker: PNPLA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PNPLA3; ADPN; C22orf20
Study NCT02951546 — Biomarker: TM6SF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TM6SF2
Study NCT00001461 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT03785197 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03780972 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study NCT02948777 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study NCT03799003 — Biomarker: TNFRSF18 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF18; AITR; GITR; UNQ319/PRO364
Study NCT01105741 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01450514 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study NCT00341952 — Biomarker: RTEL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RTEL1; C20orf41; KIAA1088; NHL
Study NCT04366479 — Biomarker: Nuclear factor erythroid 2-related factor 2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: NFE2L2; NRF2
Study NCT04366479 — Biomarker: NRF2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: NFE2L2; NRF2
Study NCT04366479 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02325505 — Biomarker: TSC1
Type: Predictive Biomarker (PRD)
Genes: KIAA0243; LAM; hamartin
Study NCT02325505 — Biomarker: TSC2
Type: Predictive Biomarker (PRD)
Genes: tuberin; LAM; PPP1R160
Study NCT00116636 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT03185494 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT03185494 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study NCT01709864 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT01146834 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01982487 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study NCT02022007 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT02022007 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT02992470 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study NCT00703326 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00703326 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03988816 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03988816 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study NCT03053089 — Biomarker: IDUA mRNA
Type: Predictive Biomarker (PRD)
Genes: IDUA
Study NCT01748396 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT01496573 — Biomarker: Crk-like protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CRKL
Study NCT01234402 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01234402 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT01234402 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT05174143 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT02919475 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03935477 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02407574 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03907722 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study NCT04872426 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study NCT02089386 — Biomarker: SOX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOX2
Study NCT02089386 — Biomarker: CDX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDX2; CDX3
Study NCT03438942 — Biomarker: SLC46A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC46A1; G21; HCP1; PCFT
Study NCT02916979 — Biomarker: VSIR mRNA
Type: Predictive Biomarker (PRD)
Genes: VSIR; C10orf54; SISP1; VISTA; PP2135; UNQ730/PRO1412
Study NCT02916979 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05201443 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study NCT05201443 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study NCT03942510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03775356 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02849704 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study NCT03016468 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT01696318 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01716611 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study NCT03077945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04386967 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00187707 — Biomarker: SLC22A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A5; OCTN2
Study NCT01417780 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study NCT00493116 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT01730677 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01208558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01608009 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00227825 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00663377 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT03012516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00471861 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00471861 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study NCT01411267 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study NCT03215173 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03432520 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study NCT02024282 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03034200 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study NCT00594152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02788916 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study NCT00526045 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00897520 — Biomarker: EGR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: EGR3; PILOT
Study NCT00443612 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00443612 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT04012918 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT00315718 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01797120 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT01797120 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT02878824 — Biomarker: EDA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDA; ED1; EDA2
Study NCT01108809 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02874716 — Biomarker: PPIA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPIA; CYPA
Study NCT00935077 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03722199 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00182871 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02703623 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study NCT04024462 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02054533 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2