AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 19352324 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9438781 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9438781 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 9438781 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 26648706 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 21621929 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 1998281 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1998281 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9736437 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9736437 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9736437 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9736437 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8422204 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8422204 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20431394 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study 20431394 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 28389217 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25731939 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 21788663 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17126775 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17126775 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10690882 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9350365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16359823 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 16359823 — Biomarker: PIPOX mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PIPOX; LPIPOX; PSO
Study 16359823 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9265931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8396082 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31045455 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 28028730 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 19325186 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 16462503 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 11744593 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9734737 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 18096843 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1516676 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31884313 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 31884313 — Biomarker: VIM mRNA
Type: Predictive Biomarker (PRD)
Genes: VIM
Study 24297946 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 24297946 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 21484793 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 12566675 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 7815178 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 7073802 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 24256483 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18544145 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12955684 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21627741 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 28693594 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 25294611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2136968 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12418395 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 7791267 — Biomarker: LTB mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB; TNFC; TNFSF3
Study 1942284 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27094558 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 16360449 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11465651 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11465651 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17097957 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17097957 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17097957 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28514601 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 26289355 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 24121755 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24121755 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24121755 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24121755 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23073140 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 12044300 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10350219 — Biomarker: CAMP mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMP; CAP18; FALL39; HSD26
Study 8983878 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 4076325 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 4076325 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22446490 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 20811348 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 10694618 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10694618 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 10694618 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 10694618 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1476278 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6097521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31246237 — Biomarker: GAL3ST1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAL3ST1; CST
Study 31246237 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31246237 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29306517 — Biomarker: PRKD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKD1; PKD; PKD1; PRKCM
Study 28003221 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24271647 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 15554580 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 9152688 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 20969662 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26833223 — Biomarker: LMX1A mRNA
Type: Predictive Biomarker (PRD)
Genes: LMX1A
Study 2656340 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 29374054 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29374054 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 19318632 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 16525578 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 12598488 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10766888 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 20676027 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 15866088 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9118296 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 11882746 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 8907208 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8907208 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29173690 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29173690 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 21615691 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 16804739 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12637702 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 10818061 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29846435 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29846435 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25312396 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 25312396 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 12021625 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 10071518 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 1705193 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 1705193 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1705193 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28714526 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 28714526 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20390483 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17634459 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17634459 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28975998 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28975998 — Biomarker: miR-106a
Type: Predictive Biomarker (PRD)
Genes: MIR106A
Study 26341987 — Biomarker: CXCR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR2; IL8RB
Study 26341987 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10638893 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9162612 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 17592349 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16298774 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 21719530 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 21719530 — Biomarker: XPC mRNA
Type: Predictive Biomarker (PRD)
Genes: XPC; XPCC
Study 21719530 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 21719530 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 21719530 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 11423055 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 9290362 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 2890806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29489078 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 28124381 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28124381 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2000798 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20522536 — Biomarker: CCN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 20522536 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 16906395 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16906395 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8658221 — Biomarker: TAOK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 31415087 — Biomarker: TACR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TACR3; NK3R; TAC3R
Study 10930153 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2436011 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 18433921 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 18433921 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 18433921 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 20076952 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9670875 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18464752 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 15894962 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15894962 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9346691 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27296819 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24532007 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 15908835 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 10917210 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 3083712 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3083712 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31698336 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31608549 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7011163 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 6338889 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 20102884 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 20102884 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 2649300 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37848 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 10812378 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10812378 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 4006252 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27907814 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25701561 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24030410 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16556417 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16556417 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 1421063 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16115394 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12796125 — Biomarker: HSPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPD1; HSP60
Study 12796125 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10802126 — Biomarker: GRAMD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRAMD4; DIP; KIAA0767
Study 26849784 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21753160 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 21753160 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19210142 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 19210142 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 16714386 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 10567624 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 10567624 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 10567624 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10567624 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8704426 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 8704426 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8704426 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 8704426 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 8704426 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 22517646 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 22517646 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 22517646 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16391376 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16391376 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9057565 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15988707 — Biomarker: PDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PDK4; PDHK4
Study 28143867 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28143867 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 27506549 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 15117041 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22827974 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 20346518 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 20346518 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 18656769 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12544629 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22132997 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 15911190 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 1986440 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6833040 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6833040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28577938 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 25761743 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 24107284 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24107284 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24107284 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12712784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10714624 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 27242220 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21594234 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 21594234 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 20658810 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 15088991 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7978470 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7978470 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 31058797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25196993 — Biomarker: Sclerostin
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: SOST; UNQ2976/PRO7455/PRO7476