AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 528285 — Biomarker: CAMP mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMP; CAP18; FALL39; HSD26
Study 30156030 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30156030 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21718536 — Biomarker: CAMP mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMP; CAP18; FALL39; HSD26
Study 9022529 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9022529 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30130712 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21913862 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 21913862 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 18984493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28283026 — Biomarker: CCL20 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL20; LARC; MIP3A; SCYA20
Study 16371294 — Biomarker: NES mRNA
Type: Predictive Biomarker (PRD)
Genes: NES; Nbla00170
Study 1464896 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20558628 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 17355300 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16285944 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 31935779 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21874538 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21874538 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19673654 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11770034 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22644708 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 18177922 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10925684 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 1397244 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 24444221 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18509970 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 16210963 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10422019 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7545380 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 7545380 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 30353743 — Biomarker: Sodium/hydrogen exchanger 3
Type: Safety Biomarker (SAF)
Genes: SLC9A3; NHE3
Study 30353743 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9702614 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 30536129 — Biomarker: LARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LARS1; KIAA1352; LARS
Study 23553154 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16954359 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3132225 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 28835238 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 29742746 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 28698075 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 28698075 — Biomarker: FBXO8 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBXO8; FBS; FBX8; DC10; UNQ1877/PRO4320
Study 25573882 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 19165198 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17956455 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10946808 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 8100421 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30786829 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27282852 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 10350666 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28618772 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22975753 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22975753 — Biomarker: CXCL13 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL13; BCA1; BLC; SCYB13
Study 22975753 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 22975753 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 21251383 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11296098 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 19697301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17898344 — Biomarker: GRIA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIA3; GLUR3; GLURC
Study 14698135 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12405649 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 12405649 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 29066159 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26287149 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23003110 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 30820429 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 16877490 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 16877490 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31938818 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22318468 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 22318468 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 23865591 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study 16335787 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12464091 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 2302053 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2302053 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20207952 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 20207952 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 20207952 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 20207952 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 20207952 — Biomarker: ABCG2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 7768254 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2283645 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26429974 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26429974 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26429974 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 19550210 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 9003220 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9003220 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8492965 — Biomarker: DPEP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DPEP1; MDP; RDP
Study 11424018 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 10268818 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22192409 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 30360970 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 30360970 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 30360970 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23360100 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 19153534 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 19153534 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17125829 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 8400675 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29703528 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 29703528 — Biomarker: NANOS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS3; NOS3
Study 29703528 — Biomarker: PPARG mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARG; NR1C3
Study 29703528 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29703528 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26321018 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 20237499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23414626 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 2807359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28608804 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 28608804 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 28608804 — Biomarker: SH2D1A mRNA
Type: Predictive Biomarker (PRD)
Genes: SH2D1A; DSHP; SAP
Study 28608804 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 25882987 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 25882987 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 24384588 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24384588 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15007746 — Biomarker: AZIN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AZIN2; ADC; KIAA1945; ODCP
Study 24881803 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 15136063 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11214732 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11214732 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24275775 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24275775 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16603428 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 3531295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28708420 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 28708420 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 8045961 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 2648890 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23680241 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 28891084 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10190788 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 31460771 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 31460771 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23353631 — Biomarker: NEDD4L mRNA
Type: Predictive Biomarker (PRD)
Genes: NEDD4L; KIAA0439; NEDL3
Study 16984385 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 15259289 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15259289 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15259289 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9071565 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9071565 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8379858 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 8379858 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29354970 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 29354970 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 23305118 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23305118 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18054621 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 14559846 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 14559846 — Biomarker: TFF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TFF1; BCEI; PS2
Study 14559846 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 14559846 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2856766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28419217 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16490580 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 15085170 — Biomarker: TEF mRNA
Type: Predictive Biomarker (PRD)
Genes: TEF; KIAA1655
Study 20560169 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20560169 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20560169 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 20560169 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 20560169 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 1325853 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 29804882 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27007793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27007793 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8081560 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 23888001 — Biomarker: FGA mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGA
Study 16729916 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23165810 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23165810 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15842525 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 15842525 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 31707329 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25042661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3802928 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 17613583 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16236107 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 16236107 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11095442 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8720425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28350537 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8173688 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27203715 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10717755 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 30512084 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 12486437 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 29768301 — Biomarker: CDKAL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKAL1
Study 25482371 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 24081186 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 24081186 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 1773136 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21919984 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11435050 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22823583 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 11440285 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11440285 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11440285 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28820857 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 23727631 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26505573 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 19961836 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 18316153 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12798827 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26647918 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10235417 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 8946232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31690988 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 31187612 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31187612 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26350816 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26350816 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26350816 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23334063 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19244376 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19244376 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12767421 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12767421 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8400077 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3081081 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 29049890 — Biomarker: RUNX3 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX3; AML2; CBFA3; PEBP2A3
Study 29049890 — Biomarker: Nicotinamide phosphoribosyltransferase
Type: Safety Biomarker (SAF)
Genes: NAMPT; PBEF; PBEF1
Study 29049890 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22421983 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19962701 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 12826783 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8782726 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1627943 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7572708 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15539725 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 24169807 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 10069685 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7628131 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1838693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26558544 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18068828 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 15194018 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15194018 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9568167 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8041179 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 17039460 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 17039460 — Biomarker: MUC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MUC2; SMUC
Study 9328361 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2