AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 15459602 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1569973 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27511476 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21655990 — Biomarker: PDE3B mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE3B
Study 21655990 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 21655990 — Biomarker: SSR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SSR3; TRAPG
Study 21655990 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 21655990 — Biomarker: CCDC14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCDC14
Study 21655990 — Biomarker: TNFRSF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1A; TNFAR; TNFR1
Study 21655990 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 21655990 — Biomarker: MAP3K1
Type: Predictive Biomarker (PRD)
Genes: MEKK; MAPKKK1
Study 21655990 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 21655990 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 14601275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10854683 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8388918 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 17209695 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 17209695 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 10341854 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 10341854 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 10341854 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10341854 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 26459421 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20463260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24296715 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 20339479 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 9365356 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 6119097 — Biomarker: DBH mRNA
Type: Predictive Biomarker (PRD)
Genes: DBH
Study 11309635 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8557525 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8557525 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 8557525 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 24913571 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 22386829 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9066353 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 22500386 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20573778 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17516992 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17516992 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11465936 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30412905 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 16567357 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18568696 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8834648 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 21247457 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 21247457 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21247457 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28138830 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 23318497 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23318497 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18259012 — Biomarker: NE
Type: Predictive Biomarker (PRD)
Study 18259012 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11500187 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10197170 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 10197170 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 8119015 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 28817199 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 26225130 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24188672 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 16480472 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11272605 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27502721 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12730085 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 31270136 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 29567358 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15878752 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study 15878752 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 2864849 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27108476 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27108476 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24675394 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 20508941 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 20508941 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 10381807 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 8682138 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1986659 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19732303 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 30049309 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19156973 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 17000947 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 17000947 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12594136 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9004102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25382404 — Biomarker: GK mRNA
Type: Predictive Biomarker (PRD)
Genes: GK
Study 26264543 — Biomarker: REST mRNA
Type: Predictive Biomarker (PRD)
Genes: REST; NRSF; XBR
Study 24478320 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9808381 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31348351 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25367222 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 23794414 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 25585263 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25585263 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 25585263 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23294670 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23294670 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 23294670 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 23294670 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 23294670 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12921985 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8677737 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 6691892 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22689807 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22689807 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 1968355 — Biomarker: ASPRV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASPRV1; SASP
Study 7258124 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31800880 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26338040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26338040 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26338040 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22040533 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18596686 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 17692354 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 22520250 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 22076546 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 2160495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29976188 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25626409 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 10894281 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6346848 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26282583 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 26282583 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26282583 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29982509 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18658112 — Biomarker: RSAD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RSAD2; CIG5
Study 12486431 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3163879 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 3163879 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17548731 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9539304 — Biomarker: Urine free cortisol
Type: Surrogate Endpoint (SUR)
Study 30942510 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20226444 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 31324663 — Biomarker: SAGE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAGE1; SAGE
Study 17451692 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11158948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3606869 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27590017 — Biomarker: INPP5K mRNA
Type: Predictive Biomarker (PRD)
Genes: INPP5K; PPS; SKIP
Study 25918759 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 23769121 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 23769121 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 23769121 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23769121 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 23769121 — Biomarker: JUN mRNA
Type: Predictive Biomarker (PRD)
Genes: JUN
Study 23769121 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23769121 — Biomarker: c-Jun N-terminal kinase
Type: Safety Biomarker (SAF)
Study 19403877 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 26580691 — Biomarker: MAX mRNA
Type: Predictive Biomarker (PRD)
Genes: MAX; BHLHD4
Study 19211941 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8071049 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29253463 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28084056 — Biomarker: OPRD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OPRD1; OPRD
Study 28084056 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 28084056 — Biomarker: OPRK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OPRK1; OPRK
Study 10696631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10696631 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31331582 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11059861 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19543195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17292412 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17292412 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 17292412 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 17292412 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 17292412 — Biomarker: KIR3DL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KIR3DL1; CD158E; NKAT3; NKB1
Study 17292412 — Biomarker: KLRD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRD1; CD94
Study 9088814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17020971 — Biomarker: GNAS mRNA
Type: Predictive Biomarker (PRD)
Genes: GNAS; GNAS1
Study 1405316 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1405316 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 30823952 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 30823952 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25366866 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17490862 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12133054 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 30612325 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 30612325 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30612325 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20945114 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19877063 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19877063 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9233591 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 9233591 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26045533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12398952 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1722834 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 30779119 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 15966882 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 12806591 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12806591 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22984128 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 18497320 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 24569690 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 20329654 — Biomarker: ETV6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV6; TEL; TEL1
Study 20329654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27620990 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 14691039 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28830875 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 26255512 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26255512 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25145323 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23610100 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23610100 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 16579697 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 7942580 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24946155 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 23349733 — Biomarker: CPT1B mRNA
Type: Predictive Biomarker (PRD)
Genes: CPT1B; KIAA1670
Study 23349733 — Biomarker: HLA-DQB1
Type: Safety Biomarker (SAF)
Genes: IDDM1; CELIAC1
Study 23349733 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 1499145 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31489188 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23669062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29096836 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16935795 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 25141100 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 25141100 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16350386 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12135589 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7631051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7631051 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30610657 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15564706 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15564706 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11460004 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 7999471 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 27881559 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18296324 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16049208 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 10383011 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 10383011 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 10383011 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 10383011 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 29546669 — Biomarker: FOXO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXO1; FKHR; FOXO1A
Study 29546669 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 24284444 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16314642 — Biomarker: MYCN mRNA
Type: Predictive Biomarker (PRD)
Genes: MYCN; BHLHE37; NMYC
Study 11923692 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 11923692 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 11923692 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 11923692 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2404087 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 326847 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26222126 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16332417 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11103221 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8267433 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 27188329 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27188329 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15675976 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)