AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 26971164 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16482467 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16440364 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12580664 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12580664 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 8462205 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 23339958 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11216935 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29548848 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29548848 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29548848 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29548848 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 27144849 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 27144849 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27144849 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15546135 — Biomarker: MYCN mRNA
Type: Predictive Biomarker (PRD)
Genes: MYCN; BHLHE37; NMYC
Study 10420071 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 10420071 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 7048338 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17414235 — Biomarker: NE
Type: Predictive Biomarker (PRD)
Study 15808325 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25959989 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25959989 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25959989 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25959989 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19567540 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15235317 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3305460 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 3305460 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 26938813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17227729 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 17227729 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17227729 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9376578 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31648883 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31648883 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31648883 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31333778 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31333778 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16507855 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24034178 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16822627 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25054452 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 25054452 — Biomarker: UCP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP3; SLC25A9
Study 22243363 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22243363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22243363 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17947724 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 9747912 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8155207 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3076795 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 28258828 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25881117 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31558345 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 31558345 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 31558345 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 31558345 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25886386 — Biomarker: EIF2AK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: EIF2AK3; PEK; PERK
Study 25886386 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 25886386 — Biomarker: HSPA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA5; GRP78
Study 25886386 — Biomarker: HYOU1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HYOU1; GRP170; ORP150
Study 25886386 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19748656 — Biomarker: PTGDR mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGDR
Study 14701888 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10099062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29231585 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29231585 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29231585 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16850002 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 12605431 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 10670908 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10670908 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10670908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16437736 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30656404 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7572757 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 2344298 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30943832 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26238707 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 22989086 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 22989086 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22989086 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19028052 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9626838 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 26857949 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 25659589 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21223712 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 18371487 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18371487 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 31871045 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 6345374 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29336388 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27574437 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27574437 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27574437 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 848704 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 19330241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26509984 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 23028039 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19493408 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19493408 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19493408 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 19493408 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 1979092 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25022125 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 25022125 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20878849 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 11442535 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9879412 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 7986713 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11327191 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 7514874 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 7514874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29769203 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 27124177 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 25703119 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10494457 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 1848169 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 31675538 — Biomarker: PPARG mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARG; NR1C3
Study 31675538 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 29604599 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29604599 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 19721013 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 17352516 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 11157138 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9626844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23899829 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23899829 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19651674 — Biomarker: Lysosomal alpha-glucosidase
Type: Safety Biomarker (SAF)
Genes: GAA
Study 21723781 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 14747423 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14747423 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11392657 — Biomarker: SOAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOAT1; ACACT; ACACT1; ACAT; ACAT1; SOAT; STAT
Study 10367611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8889266 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 25349333 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23786930 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21784046 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 13679494 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 13679494 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20137091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17432674 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 17432674 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 17432674 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 17432674 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7742723 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 31870424 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3312933 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31189655 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27609846 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27609846 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 18400709 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1748037 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 7258126 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31173468 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22264599 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 22264599 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 17211096 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17211096 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9784078 — Biomarker: LARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LARS1; KIAA1352; LARS
Study 28985328 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25352300 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23314393 — Biomarker: AMPH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMPH; AMPH1
Study 17186003 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17186003 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11928585 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12669132 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 12669132 — Biomarker: FMOD mRNA
Type: Predictive Biomarker (PRD)
Genes: FMOD; FM; SLRR2E
Study 10550467 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27367723 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23484910 — Biomarker: MTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 23484910 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 17512232 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17512232 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 26655163 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 26655163 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20130660 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11193281 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 9033197 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1670744 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6138086 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 30944048 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 28355198 — Biomarker: Osteopontin
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SPP1; BNSP; OPN; PSEC0156
Study 16586188 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28185708 — Biomarker: RUNX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX2; AML3; CBFA1; OSF2; PEBP2A
Study 28185708 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28185708 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23712068 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 18196202 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24792735 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21707914 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 17693145 — Biomarker: SLC22A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A5; OCTN2
Study 14684587 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15762 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21971743 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19463339 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 1277749 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 31423869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15223402 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15223402 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15223402 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31536766 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 22152079 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9583482 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7657029 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28677982 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 28677982 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24617605 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 24617605 — Biomarker: SLCO1B3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 17470740 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17470740 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17470740 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 15697102 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 24218517 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 24218517 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 21753226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19164401 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 17086095 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 26303694 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26303694 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21451458 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19483355 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9517371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7527104 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7527104 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27936084 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25607702 — Biomarker: LSR mRNA
Type: Predictive Biomarker (PRD)
Genes: LSR; ILDR3; LISCH
Study 3745103 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 3745103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26679060 — Biomarker: High-frequency oscillations
Type: Pharmacodynamic Biomarker (PDY)
Study 24879495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15994038 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 12585143 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 6788282 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 30188800 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 30188800 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 15803263 — Biomarker: CALD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CALD1; CAD; CDM
Study 9643568 — Biomarker: PGP mRNA
Type: Predictive Biomarker (PRD)
Genes: PGP
Study 9643568 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 9643568 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 3063328 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24885377 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 20359612 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 2662100 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 23840043 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23840043 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 23532240 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18761646 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 10457270 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 10457270 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)