AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 2283644 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2283644 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25424121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25424121 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22876543 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7671364 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7009103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24780643 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 24780643 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19703317 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19549743 — Biomarker: GHR mRNA
Type: Predictive Biomarker (PRD)
Genes: GHR
Study 19549743 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2971473 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29880069 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 23549975 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8430681 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26184257 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26184257 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26184257 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26184257 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12932111 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 8466726 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8466726 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16422913 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 6426828 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 27077693 — Biomarker: OTP mRNA
Type: Predictive Biomarker (PRD)
Genes: OTP
Study 7723681 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 7723681 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25745496 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22089970 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 11224833 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 15064583 — Biomarker: MSTN mRNA
Type: Predictive Biomarker (PRD)
Genes: MSTN; GDF8
Study 24666558 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 18390799 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study 19395131 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 9818688 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9818688 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 2653593 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24809261 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11174617 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18465329 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 18465329 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 16572117 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25351237 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23551935 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23551935 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 21327593 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 18685945 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25064769 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12453950 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10362210 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27550914 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25994549 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 23220732 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17942579 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 10811074 — Biomarker: ETV5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV5; ERM
Study 16171663 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30040033 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 17920256 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15197114 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9589354 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 9589354 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 9589354 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 7920882 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 30711862 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 20452196 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 20452196 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 20452196 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 22799613 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17278987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17278987 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 17278987 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10964037 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 6095322 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6095322 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22540269 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 25129551 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 22711428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20562609 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 12092746 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27344103 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 24588117 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17523968 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28538644 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 23438677 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 19380382 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 15700749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21073760 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 18674741 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 18674741 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9345419 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 24717258 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24717258 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 24717258 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30337315 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7835550 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25211369 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 16235184 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 16235184 — Biomarker: DHFR
Type: Safety Biomarker (SAF)
Genes: DHFR1
Study 9928752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9928752 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28865890 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 21502860 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15567095 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11149033 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11149033 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9489083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20583919 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 20583919 — Biomarker: TKT mRNA
Type: Predictive Biomarker (PRD)
Genes: TKT
Study 12370838 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 10077140 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26540210 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1706562 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6765509 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 11168303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8200946 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 8200946 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 30001903 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 24497828 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24497828 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24497828 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 24497828 — Biomarker: CCR2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCR2; CMKBR2
Study 24497828 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24349532 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 18237588 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18237588 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 9507235 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 9507235 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9507235 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31814476 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21047923 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21047923 — Biomarker: TNFRSF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1A; TNFAR; TNFR1
Study 21047923 — Biomarker: TNFRSF1B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1B; TNFBR; TNFR2
Study 21047923 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14714578 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14714578 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1357924 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 30857448 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 26938218 — Biomarker: Carbamoyl-phosphate synthetase I
Type: Safety Biomarker (SAF)
Genes: CPS1
Study 2105638 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30887496 — Biomarker: Mitochondrial frataxin
Type: Monitoring Biomarker (MOI)
Genes: FXN; FRDA; X25
Study 9039155 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8577634 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 332438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27049354 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26211623 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 22024276 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 9635947 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8162627 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28167660 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23121681 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18753738 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15487810 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9804594 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25190615 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 17218552 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15367512 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9554820 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9554820 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8060471 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3137765 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30920593 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 25196721 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 15571635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31931137 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 28866140 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 22520526 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 16681880 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 11784351 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 11784351 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 8249557 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18581440 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 1920009 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 31519283 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31519283 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25555385 — Biomarker: FTCD mRNA
Type: Predictive Biomarker (PRD)
Genes: FTCD
Study 25555385 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 25555385 — Biomarker: CHRNA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA5; NACHRA5
Study 25555385 — Biomarker: CPD mRNA
Type: Predictive Biomarker (PRD)
Genes: CPD
Study 23816271 — Biomarker: C-X-C motif chemokine 5
Type: Safety Biomarker (SAF)
Genes: CXCL5; ENA78; SCYB5
Study 23816271 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 23816271 — Biomarker: C-X-C motif chemokine 11
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 23816271 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 23816271 — Biomarker: CXCL13 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL13; BCA1; BLC; SCYB13
Study 23816271 — Biomarker: CXCL16 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL16; SCYB16; SRPSOX; UNQ2759/PRO6714
Study 21238470 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 21238470 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 21238470 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 17917321 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15536109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7942779 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7942779 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 3330987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21166828 — Biomarker: DSP mRNA
Type: Predictive Biomarker (PRD)
Genes: DSP
Study 7934491 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7934491 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23886756 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 21729166 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27798329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19828470 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 17286233 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17286233 — Biomarker: IL1RN mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RN; IL1F3; IL1RA
Study 17286233 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16128937 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 16128937 — Biomarker: IL1RN mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RN; IL1F3; IL1RA
Study 16128937 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 9929085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27679519 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 27679519 — Biomarker: Urinary total protein
Type: Safety Biomarker (SAF)
Study 24910383 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12516830 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 31116151 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11464687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28042082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26187617 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 28617540 — Biomarker: TSLP mRNA
Type: Predictive Biomarker (PRD)
Genes: TSLP
Study 15534246 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 9314428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3946248 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26890894 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 19080566 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16719171 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 16719171 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 2067212 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2067212 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2067212 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 26822613 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26822613 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22280514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9291 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30616461 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29798418 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29798418 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study 21649812 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11157688 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1