AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 8127531 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2758778 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 23083114 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 15530629 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28620891 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 1568518 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26244389 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12783630 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1312853 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10398549 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7769811 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7769811 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7769811 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1905672 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30312214 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24266733 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24266733 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24266733 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23300664 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23300664 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 23300664 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23300664 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 15791520 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2215985 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24659022 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 7835898 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26138736 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 23391845 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16475056 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 16475056 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 16475056 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9166129 — Biomarker: ALAD mRNA
Type: Predictive Biomarker (PRD)
Genes: ALAD
Study 25369444 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25369444 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26439052 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26439052 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 26439052 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17074147 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11588526 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31858865 — Biomarker: FANCC
Type: Predictive Biomarker (PRD)
Genes: FAC; FA3
Study 18650223 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 28158579 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28158579 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28158579 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28158579 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 18640378 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 18640378 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18640378 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 12667032 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12667032 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9101936 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 26792391 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8297448 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 3105906 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 30287704 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28159816 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24152375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24152375 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21918593 — Biomarker: Urinary total protein
Type: Safety Biomarker (SAF)
Study 31674641 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27003948 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27003948 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 14524580 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10739167 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 24892763 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18549331 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 28934782 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 22873657 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 20528206 — Biomarker: IGFBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP4; IBP4
Study 17761231 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15801959 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 581636 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 31851321 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31851321 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 31851321 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31444050 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 31444050 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 25380275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25380275 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25380275 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19836774 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17097943 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17097943 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9351879 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26936426 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 18540252 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 15723890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12204500 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 599107 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12172954 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2240504 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10933100 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8822346 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25509262 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25509262 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25509262 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25509262 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16259547 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 1829401 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6365468 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30006778 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 28835229 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 28835229 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21383650 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 21383650 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 21383650 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 17010798 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 14685865 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 9043728 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18325725 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18325725 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 18325725 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 18325725 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 31221870 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31221870 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26130070 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17023730 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 17023730 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 17023730 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 15492298 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15492298 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15492298 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15492298 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30617139 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22113345 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 12410192 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12410192 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 1308699 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1308699 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31780038 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31780038 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31780038 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31780038 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29493868 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 15569820 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 1832906 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 24555753 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 8627066 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8627066 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 26463708 — Biomarker: CYP19A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 24708204 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20426797 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 10470743 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 2350476 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 94176 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 31975479 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25497262 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9095076 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27281813 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 29634749 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 27038614 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23547084 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 12816726 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 1349301 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 3933893 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22364818 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15179411 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 27473326 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 25649025 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 25649025 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25649025 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 25649025 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25649025 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17705052 — Biomarker: METTL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: METTL5; DC3; HSPC133
Study 17705052 — Biomarker: TBK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TBK1; NAK
Study 15122753 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 9595363 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23037619 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23037619 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 31484539 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11422030 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 11422030 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 9716113 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9716113 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 9716113 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 18155704 — Biomarker: SLPI mRNA
Type: Predictive Biomarker (PRD)
Genes: SLPI; WAP4; WFDC4
Study 16580907 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 12742558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12742558 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 12742558 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 8221821 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3767522 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 3767522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27561827 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 27561827 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 20826250 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19383827 — Biomarker: SGK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SGK1; SGK
Study 19383827 — Biomarker: DUSP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DUSP1; CL100; MKP1; PTPN10; VH1
Study 12780397 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12780397 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16102557 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7512356 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25699397 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17591530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16046102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30943313 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 26871794 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25135040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17198906 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11565518 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11565518 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2732067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23490168 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21464685 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18317875 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18317875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15519938 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9284856 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 9284856 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9284856 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9284856 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9284856 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11388814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9094765 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2880689 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30889454 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17175489 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 17876019 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11831621 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2149913 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 2149913 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 2149913 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29065142 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29065142 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 17919378 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 22429362 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 8678366 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 27993166 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7614530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3759744 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27926473 — Biomarker: Growth/differentiation factor 15
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 18234565 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18234565 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18234565 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 18234565 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 18234565 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 6407502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15274037 — Biomarker: TPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH1; TPH; TPRH; TRPH
Study 30875961 — Biomarker: PGR mRNA
Type: Predictive Biomarker (PRD)
Genes: PGR; NR3C3
Study 30875961 — Biomarker: PRPH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRPH2; PRPH; RDS; TSPAN22
Study 7651456 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 22219100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19805643 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16943683 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 16943683 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 25948863 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 25948863 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 25948863 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25948863 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 25948863 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38