AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23857036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22633423 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17678487 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27781388 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20820817 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17869297 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 8111799 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27823800 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26056336 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15113814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9150899 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 3500051 — Biomarker: Plasma methotrexate
Type: Surrogate Endpoint (SUR)
Study 19259830 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24531602 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22374408 — Biomarker: FFAR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FFAR1; GPR40
Study 11015237 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31175052 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 24872326 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17852827 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 17852827 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8879847 — Biomarker: Alpha-glutathione S-transferase
Type: Safety Biomarker (SAF)
Study 22392817 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22392817 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15855258 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 15855258 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 10374456 — Biomarker: STC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STC1; STC
Study 7837152 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7837152 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 3534593 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18098237 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7040955 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 30069803 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 24387048 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 17237312 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10368879 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10368879 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7046434 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31092172 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29223955 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29223955 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25339309 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 14713325 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 14713325 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9118514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8419392 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30866659 — Biomarker: CHRNA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA3; NACHRA3
Study 17381970 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14980936 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11446564 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30646422 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 30646422 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 30646422 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9834590 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28902073 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28902073 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 26168736 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 26168736 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 26168736 — Biomarker: Macrophage inflammatory protein 1-alpha
Type: Monitoring Biomarker (MOI)
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 26168736 — Biomarker: C-C motif chemokine 4
Type: Monitoring Biomarker (MOI)
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 26168736 — Biomarker: Small-inducible cytokine A11
Type: Predictive Biomarker (PRD)
Genes: CCL11; SCYA11
Study 21600129 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 21600129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12904840 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 12904840 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 4103276 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 7503838 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17679044 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17679044 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15385805 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9829346 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9829346 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 29335039 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 29335039 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 19067474 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 2442538 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14604194 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9148240 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 29713800 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29713800 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 29713800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27658756 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 26351027 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15129927 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11304901 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 9345339 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9345339 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 27742728 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17716953 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8860007 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 31058762 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27251974 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 21053621 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15848571 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15848571 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9620309 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29051306 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14739801 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 14739801 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3150824 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 28816509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7748214 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7748214 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7748214 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 24218952 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 11460891 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 30527263 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30527263 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22728482 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 19941906 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19941906 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study 2280233 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2280233 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27055960 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27055960 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27055960 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20845101 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20845101 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12573788 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 2000792 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2000792 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2000792 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 26137952 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28421240 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 26136593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26136593 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 11834646 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7618675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17308528 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17308528 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15179180 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15179180 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 17059015 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 15546231 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3295034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31618456 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 26572609 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study 31951771 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 29354930 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29354930 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29354930 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29354930 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29354930 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27631719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26586732 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 26586732 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23444204 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 2081608 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 25123170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18688814 — Biomarker: PLG mRNA
Type: Predictive Biomarker (PRD)
Genes: PLG
Study 18688814 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18688814 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 3559982 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20102300 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15914552 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2650734 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2650734 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2650734 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26282654 — Biomarker: IRF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRF4; MUM1
Study 26282654 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 26282654 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 26282654 — Biomarker: MAX mRNA
Type: Predictive Biomarker (PRD)
Genes: MAX; BHLHD4
Study 26282654 — Biomarker: H1-4 mRNA
Type: Predictive Biomarker (PRD)
Genes: H1-4; H1F4; HIST1H1E
Study 26282654 — Biomarker: Retinoblastoma-associated protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: RB1
Study 26282654 — Biomarker: EGR1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: EGR1; KROX24; ZNF225
Study 26282654 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 26282654 — Biomarker: TRAF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRAF3; CAP-1; CRAF1; TRAFAMN
Study 26282654 — Biomarker: TENT5C mRNA
Type: Predictive Biomarker (PRD)
Genes: TENT5C; FAM46C
Study 26282654 — Biomarker: DIS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DIS3; KIAA1008; RRP44
Study 23692303 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20562170 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 9538975 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4558903 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11929404 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 7978397 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28449690 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20021666 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 11265776 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 27146814 — Biomarker: ABCG2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 19702471 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 2507321 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 45463 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31302338 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 23280225 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 21056418 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 21056418 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17073812 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8336224 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8336224 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 26928670 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 26928670 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 26928670 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24572997 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20306554 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26474541 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 11374763 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8060581 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15242697 — Biomarker: TGFB1
Type: Safety Biomarker (SAF)
Genes: CED; TGFbeta
Study 15242697 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15242697 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 11095487 — Biomarker: SERPINA7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA7; TBG
Study 11095487 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9050018 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24292894 — Biomarker: EDA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDA; ED1; EDA2
Study 20637377 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 16703004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31331574 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17152004 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 25362864 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 25692840 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17456124 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 15081625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2559485 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 29195999 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29195999 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29195999 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 25520280 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25520280 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 9002079 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8240880 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27017611 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31641325 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22359978 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 22359978 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11329232 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11329232 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 29216947 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16758078 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8390795 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 27051354 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 23824870 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 22566583 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22566583 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16631259 — Biomarker: CD24 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD24; CD24A
Study 8741040 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29048765 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 29048765 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 24439313 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22625863 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 13680141 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)