AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 29352831 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16810542 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31558549 — Biomarker: HNF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: HNF1A; TCF1
Study 31558549 — Biomarker: HNF4A mRNA
Type: Predictive Biomarker (PRD)
Genes: HNF4A; HNF4; NR2A1; TCF14
Study 7534966 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 16365065 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9372795 — Biomarker: EMP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EMP1; B4B; TMP
Study 2861311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3121830 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9669456 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 7822066 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 29856651 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12747344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30457088 — Biomarker: PKD2L1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PKD2L1; PKD2L; PKDL; TRPP3
Study 22305836 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11811936 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 27687824 — Biomarker: UCN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCN3; SPC
Study 22388798 — Biomarker: SELE mRNA
Type: Predictive Biomarker (PRD)
Genes: SELE; ELAM1
Study 22388798 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 22388798 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study 22388798 — Biomarker: GNAS mRNA
Type: Predictive Biomarker (PRD)
Genes: GNAS; GNAS1
Study 22388798 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 22388798 — Biomarker: Coagulation factor Va
Type: Safety Biomarker (SAF)
Genes: F5
Study 22388798 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 22388798 — Biomarker: PDE4D mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE4D; DPDE3
Study 22388798 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 17689196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19252247 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19834806 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 30510410 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 17641457 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11798458 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11798458 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9716140 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 30971225 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 19387330 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 30387043 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 8600865 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 6844301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24798657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20350135 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 20350135 — Biomarker: ANKK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANKK1; PKK2; SGK288
Study 16006728 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27325862 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 27325862 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24225325 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18296421 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18296421 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 15756004 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15756004 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25688638 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17712655 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 31848757 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31035478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18431498 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18431498 — Biomarker: TNFRSF1B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1B; TNFBR; TNFR2
Study 18431498 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 18431498 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 27997877 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 27997877 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17955771 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15886538 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8705091 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15632335 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15632335 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15632335 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10401916 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 7593425 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7593425 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23323897 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15975277 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15975277 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8912771 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 1655261 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1655261 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30669665 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26873498 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26873498 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17081540 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31816038 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12871402 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 11908577 — Biomarker: LIF mRNA
Type: Predictive Biomarker (PRD)
Genes: LIF; HILDA
Study 839327 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 31743617 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 31743617 — Biomarker: HDAC4 mRNA
Type: Predictive Biomarker (PRD)
Genes: HDAC4; KIAA0288
Study 31743617 — Biomarker: MEF2C mRNA
Type: Predictive Biomarker (PRD)
Genes: MEF2C
Study 31743617 — Biomarker: FST mRNA
Type: Predictive Biomarker (PRD)
Genes: FST
Study 24621355 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15280147 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27859410 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12972442 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 2819522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16682309 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 14996470 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 14996470 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 3327930 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15599642 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 28865249 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 7589023 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 225750 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24480113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22763473 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17962596 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1934003 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1934003 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12114041 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12114041 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 12114041 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 12114041 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 10220224 — Biomarker: GRIN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIN1; NMDAR1
Study 10220224 — Biomarker: GRIN2A mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIN2A; NMDAR2A
Study 2191584 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 381954 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 24494790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27305912 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 20136764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12432838 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 9167559 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8466725 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29964324 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 7783099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7783099 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 18572029 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 10599715 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 10599715 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30805617 — Biomarker: FXYD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FXYD1; PLM
Study 17374660 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15098169 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11216756 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 9798655 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7886971 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 26188380 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 20386359 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 20386359 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 10808698 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 1599986 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1746997 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 1746997 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26656144 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 26656144 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24288691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23017309 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23017309 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23017309 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17620054 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 11673342 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29077146 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26243579 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 23847491 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 23847491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19223284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29644962 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29644962 — Biomarker: TJP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TJP1; ZO1
Study 18505083 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9257199 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3706190 — Biomarker: PDXP mRNA
Type: Predictive Biomarker (PRD)
Genes: PDXP; CIN; PLP; PLPP
Study 26722670 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 22803768 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 22803768 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7875147 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 22753402 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 31725787 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31725787 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16386890 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 30673028 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 30442354 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 30442354 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 11788558 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 11788558 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 2576246 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31520543 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 30204517 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 26083409 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26083409 — Biomarker: CCR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 26083409 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 19293261 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12918546 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 1294196 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1294196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24483103 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 24189463 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 24189463 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24189463 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8402803 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 8402803 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 27863807 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25009196 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 25009196 — Biomarker: KLRK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRK1; D12S2489E; NKG2D
Study 2101781 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28449709 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 21434338 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 21434338 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 21434338 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 9691229 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 7918062 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7918062 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 7918062 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 7918062 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 28196256 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21159786 — Biomarker: C1QTNF9 mRNA
Type: Predictive Biomarker (PRD)
Genes: C1QTNF9; C1QTNF9A; UNQ6503/PRO21380
Study 21159786 — Biomarker: PPBP mRNA
Type: Predictive Biomarker (PRD)
Genes: PPBP; CTAP3; CXCL7; SCYB7; TGB1; THBGB1
Study 21159786 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31860959 — Biomarker: DNMT3A mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMT3A
Study 31860959 — Biomarker: ZEB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZEB1; AREB6; TCF8
Study 31860959 — Biomarker: MMP13 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP13
Study 31860959 — Biomarker: CTNNB1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CTNNB1; CTNNB; OK/SW-cl.35; PRO2286
Study 31860959 — Biomarker: miR-200c
Type: Safety Biomarker (SAF)
Genes: MIR200C
Study 26716877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17351383 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16351772 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11181473 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 30578714 — Biomarker: CDKN2A mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2A; CDKN2; MTS1
Study 30578714 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 15641601 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20947098 — Biomarker: CXCL13 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL13; BCA1; BLC; SCYB13
Study 20947098 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC
Study 20947098 — Biomarker: CCL20 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL20; LARC; MIP3A; SCYA20
Study 25319074 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 10853298 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 8704111 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1793331 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25139539 — Biomarker: PDPN mRNA
Type: Predictive Biomarker (PRD)
Genes: PDPN; GP36; PSEC0003; PSEC0025
Study 22464259 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 22079192 — Biomarker: SLC39A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC39A2; ZIP2
Study 29779821 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27210234 — Biomarker: FMOD mRNA
Type: Predictive Biomarker (PRD)
Genes: FMOD; FM; SLRR2E
Study 2268740 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2268740 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 23770157 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 22303710 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22303710 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 10708256 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1283590 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29364489 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 27005405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16485047 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3606739 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17371478 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 12928050 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8378100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23575741 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12912805 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11176015 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1