AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05127096 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study NCT03950245 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT03677648 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study NCT00255398 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT00237692 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02795260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02795260 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT04301882 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study NCT00086658 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study NCT01017653 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT02561351 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study NCT00732069 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study NCT06398678 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study NCT02223247 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study NCT01319591 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT01181518 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study NCT01181518 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT01181518 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study NCT03062566 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study NCT03062566 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study NCT02362893 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01919333 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT02227784 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00212979 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT00212979 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study NCT00974519 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT02891733 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02891733 — Biomarker: NTS mRNA
Type: Predictive Biomarker (PRD)
Genes: NTS
Study NCT02891733 — Biomarker: NTSR1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: NTSR1; NTRR
Study NCT02891733 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT02144012 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04586894 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04586894 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study NCT03225183 — Biomarker: ID1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ID1; BHLHB24; ID
Study NCT03673488 — Biomarker: P4HB mRNA
Type: Predictive Biomarker (PRD)
Genes: P4HB; ERBA2L; PDI; PDIA1; PO4DB
Study NCT00018252 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study NCT04157088 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study NCT02664584 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT02664584 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02664584 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01988922 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study NCT03179306 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study NCT04480788 — Biomarker: CD7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD7
Study NCT01830361 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study NCT01830361 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study NCT01152567 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT03164720 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study NCT02480764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03030196 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study NCT03030196 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study NCT01594281 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01594281 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT00201019 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02778516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00914134 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01735149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01735149 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01735149 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04215601 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study NCT00076934 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study NCT04423640 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT04423640 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02283775 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study NCT01264809 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03411746 — Biomarker: Osteopontin
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SPP1; BNSP; OPN; PSEC0156
Study NCT01193283 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT01523171 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study NCT01523171 — Biomarker: JAK2
Type: Predictive Biomarker (PRD)
Genes: JTK10
Study NCT02156999 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03899194 — Biomarker: PRKCB mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKCB; PKCB; PRKCB1
Study NCT02745223 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00004244 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study NCT00824265 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT02125266 — Biomarker: PTGDS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGDS; PDS
Study NCT01749137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02598544 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study NCT01230580 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT03832400 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT03605043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04598984 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03392909 — Biomarker: COL7A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL7A1
Study NCT03558854 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study NCT03558854 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study NCT00039273 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03700775 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01964742 — Biomarker: ITPA mRNA
Type: Predictive Biomarker (PRD)
Genes: ITPA; C20orf37; My049; OK/SW-cl.9
Study NCT02325271 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02325271 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT01411332 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study NCT03308019 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study NCT04397107 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT01028651 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study NCT01028651 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study NCT02843334 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study NCT01405898 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02320110 — Biomarker: UCP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP1; SLC25A7; UCP
Study NCT04344405 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04344405 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04344405 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT04005664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03056859 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04258111 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study NCT03819413 — Biomarker: AQP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP4
Study NCT02066532 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04271514 — Biomarker: CCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR4; CMKBR4
Study NCT02857270 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study NCT02857270 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00738452 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study NCT04125706 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT00500786 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03132792 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study NCT03132792 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT03178084 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT02349724 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study NCT00056784 — Biomarker: CCN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCN2; CTGF; HCS24; IGFBP8
Study NCT02689336 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02689336 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02689336 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study NCT01226628 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT00001296 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00001296 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT03341650 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04301726 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study NCT02902016 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study NCT03783117 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00387972 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT01329770 — Biomarker: FMR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMR1
Study NCT01089062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05117437 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study NCT05217147 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT05217147 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study NCT02002442 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study NCT03841214 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study NCT04390178 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT02268344 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT03977987 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT03990363 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study NCT02119741 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT03476980 — Biomarker: DCC mRNA
Type: Predictive Biomarker (PRD)
Genes: DCC; IGDCC1
Study NCT01223612 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00515645 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02997800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00300469 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00300469 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03136185 — Biomarker: KDM1A mRNA
Type: Predictive Biomarker (PRD)
Genes: KDM1A; AOF2; KDM1; KIAA0601; LSD1
Study NCT04485078 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study NCT01697800 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study NCT01247220 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01247220 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT04013490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04013490 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02310971 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study NCT01030016 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03402373 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT02274649 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study NCT01688622 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study NCT02610218 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02610218 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study NCT01627067 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study NCT01627067 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT00682799 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study NCT00682799 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT03532893 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00019006 — Biomarker: RAS peptides
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03449537 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT01728805 — Biomarker: CCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR4; CMKBR4
Study NCT01644474 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study NCT01644474 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03320460 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03837821 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study NCT01822548 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT03387514 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03607903 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03799679 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study NCT00904150 — Biomarker: PGR mRNA
Type: Predictive Biomarker (PRD)
Genes: PGR; NR3C3
Study NCT00904150 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT00904150 — Biomarker: SYNE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SYNE1; C6orf98; KIAA0796; KIAA1262; KIAA1756; MYNE1
Study NCT04466085 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT01751321 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT00876512 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT05744076 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00904826 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study NCT03820167 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT00975221 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study NCT03613714 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03319030 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study NCT02037828 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study NCT03145805 — Biomarker: Alpha-1-acid glycoprotein 1
Type: Monitoring Biomarker (MOI)
Genes: ORM1; AGP1
Study NCT03000140 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03002545 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00783471 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02951910 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT02171429 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01657669 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT03443375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02037802 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00303238 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01949194 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT03365375 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study NCT00289237 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00505726 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study NCT03055247 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT04023409 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study NCT00005200 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01677780 — Biomarker: MDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM2
Study NCT00975572 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study NCT00005763 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01957423 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04367402 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885
Study NCT00005207 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study NCT05515926 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02256189 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT02720510 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT02766153 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT02013973 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT02487537 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT01013376 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT02316691 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT02316691 — Biomarker: CXCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR5; BLR1; MDR15
Study NCT04127084 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT04127084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04215185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01565200 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03668665 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT02684578 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT03663777 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00956280 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT01554943 — Biomarker: TNNT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNNT1; TNT
Study NCT01201070 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study NCT01968096 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study NCT04386564 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT04386564 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT01291329 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT03071224 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU