AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23416349 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10404948 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study 7356683 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30237250 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 27001444 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20856830 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12842524 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31563947 — Biomarker: TLR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR1; KIAA0012
Study 31563947 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 31563947 — Biomarker: TLR6 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR6
Study 31563947 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 31563947 — Biomarker: RORC mRNA
Type: Predictive Biomarker (PRD)
Genes: RORC; NR1F3; RORG; RZRG
Study 31563947 — Biomarker: TBX21 mRNA
Type: Predictive Biomarker (PRD)
Genes: TBX21; TBET; TBLYM
Study 31563947 — Biomarker: CXCR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR3; GPR9
Study 31563947 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31563947 — Biomarker: CASP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CASP1; IL1BC; IL1BCE
Study 26882921 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22795099 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18806043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10411851 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28286249 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18848765 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 16427852 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 8222684 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8222684 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31413010 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31413010 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25429531 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20951323 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10919591 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27978511 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27978511 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27881458 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22004765 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 19496921 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 19496921 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 16914600 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16914600 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 16914600 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15362523 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 7943463 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 3148039 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20800102 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 10663450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23118302 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 23118302 — Biomarker: APOC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOC1
Study 23118302 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 23118302 — Biomarker: PLA2G7 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G7; PAFAH
Study 23118302 — Biomarker: ABCG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 23118302 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23087401 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20564914 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 18460663 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16368822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23873118 — Biomarker: ADRA2A mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRA2A; ADRA2R; ADRAR
Study 15519006 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25212234 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22795340 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 22795340 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 22795340 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20601740 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8535541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8535541 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 1966794 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 1966794 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 9485128 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 9485128 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2539714 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 778569 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28583116 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 26037632 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20108779 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 15283931 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study 23361105 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11338300 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 9390107 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 30093449 — Biomarker: MYCN mRNA
Type: Predictive Biomarker (PRD)
Genes: MYCN; BHLHE37; NMYC
Study 24227801 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 18619772 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18619772 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18619772 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 8780339 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1361083 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19237002 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19237002 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2545721 — Biomarker: SSB mRNA
Type: Predictive Biomarker (PRD)
Genes: SSB
Study 24279904 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 24279904 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 19108937 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17207719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 336052 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12138347 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20010459 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 28371205 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 28371205 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 28371205 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 21344271 — Biomarker: Hypoxia-inducible factor 1-alpha
Type: Predictive Biomarker (PRD)
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 21344271 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 19057513 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study 19057513 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19057513 — Biomarker: AGTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study 20535927 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20535927 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20535927 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 15574127 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15574127 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 7786833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12086366 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12086366 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30047538 — Biomarker: KCNK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNK3; TASK; TASK1
Study 18574771 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 18574771 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10412920 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31530556 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 22772319 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11471577 — Biomarker: SP9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP9
Study 8060627 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25960104 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 15123336 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 8160983 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3128465 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 30303980 — Biomarker: CXCR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR3; GPR9
Study 30303980 — Biomarker: CXCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR5; BLR1; MDR15
Study 30303980 — Biomarker: CCR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 26545149 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26545149 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26253520 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 26253520 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18563311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24737712 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 24737712 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24737712 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24737712 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10589610 — Biomarker: Alpha-glutathione S-transferase
Type: Safety Biomarker (SAF)
Study 2239719 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31842993 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28969350 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 12572707 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9498726 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 2131867 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 217271 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30040523 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 30040523 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27763932 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19923501 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 19923501 — Biomarker: Alpha-glutathione S-transferase
Type: Safety Biomarker (SAF)
Study 19923501 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 19923501 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 17574511 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2974791 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 15864235 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15864235 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15864235 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30089729 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 30089729 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 26384407 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 1329475 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1329475 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27520015 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 1336212 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6231418 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 17660728 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12200770 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7750308 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 25164908 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 25164908 — Biomarker: UIMC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: UIMC1; RAP80; RXRIP110
Study 8051620 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16981102 — Biomarker: HGD mRNA
Type: Predictive Biomarker (PRD)
Genes: HGD; HGO
Study 10470326 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24820653 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 21930149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8536121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17199237 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 19619705 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 12957683 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12957683 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9816131 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 21910335 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18303965 — Biomarker: CNTF mRNA
Type: Predictive Biomarker (PRD)
Genes: CNTF
Study 12939735 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12939735 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 10689152 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 31392213 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24937024 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24937024 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31376167 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 30277655 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 29241909 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study 2304407 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2304407 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 31626654 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 12891225 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 10374861 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 10374861 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 2065470 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25120110 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17213873 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17213873 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 105656 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 26880570 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 10585387 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7538555 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27977473 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17222848 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29941520 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 29941520 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29941520 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 29941520 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 25033919 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 20728565 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 31900148 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 3813189 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 23041092 — Biomarker: ADAMTS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 23041092 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21474219 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 17947225 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 15106359 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18426457 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12634260 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 11388815 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9252945 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 3326920 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3326920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31683617 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 25799208 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21235822 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 15205083 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25986600 — Biomarker: CYP4F2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP4F2
Study 25986600 — Biomarker: CYP2J2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2J2
Study 25986600 — Biomarker: EPHX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPHX2
Study 19228414 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9203932 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 7869908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7869908 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 367576 — Biomarker: MERTK mRNA
Type: Predictive Biomarker (PRD)
Genes: MERTK; MER
Study 31629881 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 28089917 — Biomarker: DICER1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DICER1; DICER; HERNA; KIAA0928
Study 28089917 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1