AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 21239636 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 7964947 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 10870746 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 26830098 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 26830098 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 26830098 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 26830098 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 26830098 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26830098 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 24274379 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24274379 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24274379 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24274379 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 24274379 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 22227851 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12665916 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 8074071 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21482217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3691557 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 27522247 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 25479285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20028815 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18360262 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28658431 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26071836 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19729908 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 19729908 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14760893 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30648524 — Biomarker: WNT16 mRNA
Type: Predictive Biomarker (PRD)
Genes: WNT16
Study 30648524 — Biomarker: CCL20 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL20; LARC; MIP3A; SCYA20
Study 30648524 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 30576794 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 22250063 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17284910 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 28224232 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 28224232 — Biomarker: Macrophage inflammatory protein 1-alpha
Type: Monitoring Biomarker (MOI)
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 28224232 — Biomarker: C-C motif chemokine 4
Type: Monitoring Biomarker (MOI)
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 28224232 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 799551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25474080 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 15136071 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 2830189 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2830189 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30963177 — Biomarker: EED mRNA
Type: Predictive Biomarker (PRD)
Genes: EED
Study 23491407 — Biomarker: NIBAN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NIBAN1; C1orf24; FAM129A; NIBAN; GIG39
Study 23491407 — Biomarker: SYNPO2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SYNPO2
Study 20153492 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 9220217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9220217 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9220217 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25074756 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 25074756 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 23089925 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23089925 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18398079 — Biomarker: ADAM17 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM17; CSVP; TACE
Study 21067347 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10820175 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 1514338 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29943100 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 11980869 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 6982270 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 31192515 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 26950019 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 26878318 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 25392505 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 17980044 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 8562236 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 30605396 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30605396 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30605396 — Biomarker: Angiopoietin-1
Type: Monitoring Biomarker (MOI)
Genes: ANGPT1; KIAA0003
Study 21317789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14665887 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 25364081 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19140845 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17717439 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 17592908 — Biomarker: CPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPZ
Study 9342601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8518523 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 2545640 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30973001 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30973001 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 30973001 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29025845 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 22939927 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 19863177 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 6402075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19112278 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19112278 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 17309328 — Biomarker: PAFAH1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study 15517671 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 8056006 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28681366 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 21455728 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 16507605 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12601267 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 7683800 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 26573041 — Biomarker: POR mRNA
Type: Predictive Biomarker (PRD)
Genes: POR; CYPOR
Study 23840403 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23840403 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 23840403 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23840403 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 23840403 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 16493496 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 16493496 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 10211848 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8874330 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17076775 — Biomarker: PCLAF mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 11504824 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11504824 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9116394 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6657002 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 23429593 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 14505296 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 22184366 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16277783 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16277783 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2110972 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 21514017 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12145008 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2110336 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 382381 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29284183 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 29284183 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26867046 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12752488 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10218722 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29273007 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 26333499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11297596 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31606265 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 31651370 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24052362 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24052362 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7535990 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 7535990 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30662331 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study 23711188 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 21850387 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 12191965 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12191965 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 19917367 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15049991 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 21786177 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18609080 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18609080 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18609080 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 16869719 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 2142633 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1420010 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15946834 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 10344294 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8559498 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 26717057 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26717057 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 8740302 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 8740302 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 26721259 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12139647 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8001304 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8001304 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8001304 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24288395 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 24288395 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24288395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15289996 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 10442212 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24341511 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24341511 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10950448 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9018408 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 9018408 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 22084404 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22084404 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 18991094 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 16466167 — Biomarker: BSG mRNA
Type: Predictive Biomarker (PRD)
Genes: BSG; UNQ6505/PRO21383
Study 16466167 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16466167 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22081618 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22081618 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9663812 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31652195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25280085 — Biomarker: SYK mRNA
Type: Predictive Biomarker (PRD)
Genes: SYK
Study 23459567 — Biomarker: CD52 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD52; CDW52; HE5
Study 21831004 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21831004 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16871129 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 10952230 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 17233546 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15618034 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 10458007 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28854085 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25925203 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 16446400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10598608 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 23813620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8101550 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29502373 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28582403 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28582403 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 28582403 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 28582403 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 19386814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11157316 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18795972 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10437215 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 30549489 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30549489 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24703391 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 24703391 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 28315568 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30839100 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 24474034 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 7523775 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30694699 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 20473047 — Biomarker: SEMG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEMG1; SEMG
Study 11049910 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 11049910 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 2485273 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 21196441 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 7636641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 336116 — Biomarker: CLYBL mRNA
Type: Predictive Biomarker (PRD)
Genes: CLYBL; CLB
Study 27633965 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 3925888 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 23245621 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23245621 — Biomarker: Osteopontin
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SPP1; BNSP; OPN; PSEC0156
Study 17672828 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11000340 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1363497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2877644 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31362691 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 28152655 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28152655 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 26081016 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26081016 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26081016 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26081016 — Biomarker: Plasma DNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12743862 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1486738 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)