AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24579364 — Biomarker: Osteopontin
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SPP1; BNSP; OPN; PSEC0156
Study 24579364 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 12456509 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 29710212 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 20646412 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31809403 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31809403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12637460 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 12637460 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26073878 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23224687 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12562833 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 12562833 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2865417 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 26847108 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23370085 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 21983154 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 20482275 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12357148 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 18035192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12189228 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 10449886 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 370586 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27817766 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27817766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11119398 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27769282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16293984 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 16293984 — Biomarker: ADAMTS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 8017448 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8017448 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8017448 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26525562 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 19280938 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19280938 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 10890482 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 9351079 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30224390 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30224390 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 30224390 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 30224390 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 24129948 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 15608430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15608430 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27015911 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 27015911 — Biomarker: OGG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OGG1; MMH; MUTM; OGH1
Study 27015911 — Biomarker: MDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM2
Study 27015911 — Biomarker: APEX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 27015911 — Biomarker: XPC mRNA
Type: Predictive Biomarker (PRD)
Genes: XPC; XPCC
Study 11213068 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26614597 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 26614597 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26775516 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 20643699 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16754836 — Biomarker: CHRNA7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA7; NACHRA7
Study 2178941 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 2178941 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 2178941 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 23193746 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 1922206 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22372774 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17263634 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15106814 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15106814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9746884 — Biomarker: SPINK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPINK1; PSTI
Study 9746884 — Biomarker: SLPI mRNA
Type: Predictive Biomarker (PRD)
Genes: SLPI; WAP4; WFDC4
Study 16420280 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15087583 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 11168457 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11168457 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9355889 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9355889 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 25820842 — Biomarker: TRIM32 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM32; HT2A
Study 19278589 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19278589 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15030978 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 15030978 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15030978 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11795467 — Biomarker: Heat shock 70 kDa
Type: Safety Biomarker (SAF)
Study 21148517 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16570004 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18312763 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18312763 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8731519 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18664593 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16200596 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 29480202 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 18928633 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 1071665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26312576 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15257176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7997386 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3348162 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30108107 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 30108107 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 24736773 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15486010 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8622045 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 30192638 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 30192638 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28064380 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21135547 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21135547 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9481597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15066461 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15066461 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 15066461 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15066461 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9569566 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8059778 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8059778 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8059778 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30817982 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 27902529 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 25931293 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25931293 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7237920 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19922127 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 15049459 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11493282 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 9489907 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 25771294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18466681 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16527165 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2938923 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 31735618 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30253968 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 27427876 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20337610 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10711744 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25796858 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study 1592541 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30401001 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 8928847 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8928847 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27175799 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26703923 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22699446 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 10049268 — Biomarker: EMB mRNA
Type: Predictive Biomarker (PRD)
Genes: EMB
Study 2176098 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 2176098 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 2176098 — Biomarker: SLC4A7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC4A7; BT; NBC2; NBC2B; NBC3; NBCn1; SBC2; SLC4A6
Study 30580857 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15978969 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 22500387 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16236169 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 8563848 — Biomarker: FST mRNA
Type: Predictive Biomarker (PRD)
Genes: FST
Study 24415446 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 23200590 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 15342839 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 3054433 — Biomarker: HGD mRNA
Type: Predictive Biomarker (PRD)
Genes: HGD; HGO
Study 10227067 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 27658925 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24717427 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22076595 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18495964 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 30254212 — Biomarker: SEPTIN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEPTIN3; SEP3; SEPT3
Study 26409670 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3770869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3770869 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22767199 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21607581 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 12935406 — Biomarker: CPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPB1; CPB; PCPB
Study 8090095 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30756274 — Biomarker: PELI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PELI1; PRISM
Study 8818067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25250780 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7589766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27346393 — Biomarker: SPR mRNA
Type: Predictive Biomarker (PRD)
Genes: SPR
Study 25861836 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 25861836 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 25861836 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 28727639 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 16206603 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12431323 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7737712 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27807887 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24121143 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24121143 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 7575694 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7575694 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2403063 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 29340678 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29340678 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20438534 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20438534 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18356633 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19251872 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 19251872 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18061058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21712261 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 22995323 — Biomarker: CXCR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR2; IL8RB
Study 22995323 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22995323 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 11498896 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 11498896 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8068472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8068472 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8068472 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 3181276 — Biomarker: PCLAF mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 21174610 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 18339132 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 9365042 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 9365042 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 27183909 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 19892414 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19892414 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16198248 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12391509 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 1962805 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17367707 — Biomarker: APOB mRNA
Type: Predictive Biomarker (PRD)
Genes: APOB
Study 11777296 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11777296 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3295935 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26745101 — Biomarker: BCAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCAT1; BCT1; ECA39
Study 26745101 — Biomarker: IKZF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IKZF1; IK1; IKAROS; LYF1; ZNFN1A1
Study 21668963 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 15298240 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 12959269 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 25951630 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25951630 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25951630 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17322150 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7603218 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 2665884 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 391427 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 31994720 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 9663813 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 29241890 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 29241890 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24231479 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19175892 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 19175892 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3276824 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 31564697 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 17633358 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14999518 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26116711 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26116711 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 26116711 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 23411128 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11069188 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3011891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)