AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 12753271 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 8712091 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 8338943 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8338943 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18076250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 407056 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31365188 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 31365188 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21302487 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12059064 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18657146 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 29451696 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8607100 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 8607100 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 26620682 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15973830 — Biomarker: LDHA mRNA
Type: Predictive Biomarker (PRD)
Genes: LDHA; PIG19
Study 15973830 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27720505 — Biomarker: ETV6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV6; TEL; TEL1
Study 27720505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16633088 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20159703 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30684710 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 25662857 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23308361 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21127274 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19149269 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16534180 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 30474929 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22690943 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 22293584 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22293584 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19927132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2128475 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26123388 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23804517 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 1283192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30372582 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 29122196 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 27373347 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 10758465 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23905576 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 10648452 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 22629160 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 22629160 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22629160 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22629160 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 22629160 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 16706150 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30249940 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28411114 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 25627664 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 20139391 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 20139391 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 16147905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1391736 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 9220214 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 8345495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11557910 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24938502 — Biomarker: NDRG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NDRG1; CAP43; DRG1; RTP
Study 22800889 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 17698695 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17698695 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 7002427 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7002427 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 30410041 — Biomarker: CTLA4
Type: Predictive Biomarker (PRD)
Genes: CD152; CD; GSE; CTLA-4
Study 28992296 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19426116 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 19426116 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 17539025 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18512710 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17023704 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8400756 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31078666 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21244590 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 19631303 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27614458 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20413518 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12882849 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9206242 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3329516 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 3329516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29782218 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29782218 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 20728082 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9468008 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 356792 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26124351 — Biomarker: VEGFC mRNA
Type: Predictive Biomarker (PRD)
Genes: VEGFC
Study 26124351 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 26124351 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26124351 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11078841 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 7514156 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7514156 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30021626 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30021626 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20307245 — Biomarker: MLH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MLH1; COCA2
Study 20307245 — Biomarker: DNA mismatch repair protein MSH2
Type: Predictive Biomarker (PRD)
Genes: MSH2
Study 18250501 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 12797703 — Biomarker: EMB mRNA
Type: Predictive Biomarker (PRD)
Genes: EMB
Study 29519283 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 29519283 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29519283 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27614450 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27614450 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21389794 — Biomarker: CTLA4
Type: Predictive Biomarker (PRD)
Genes: CD152; CD; GSE; CTLA-4
Study 18484971 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6441544 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31612844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27577516 — Biomarker: XRCC1
Type: Safety Biomarker (SAF)
Genes: RCC
Study 17426069 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23483 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 23579036 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16330517 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30499426 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 27600862 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 27600862 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18760124 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 8813907 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22562731 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22562731 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 18564805 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17893574 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11474662 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11474662 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 9727378 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9727378 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 7508536 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2837830 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 23622913 — Biomarker: PTMA mRNA
Type: Predictive Biomarker (PRD)
Genes: PTMA; TMSA
Study 7802981 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24274213 — Biomarker: FMN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMN1; FMN; LD
Study 18469018 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12565082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20151970 — Biomarker: PTGDS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGDS; PDS
Study 11195030 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30098076 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 30098076 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30098076 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30098076 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27767991 — Biomarker: Beta-secretase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: BACE1; BACE; KIAA1149
Study 15591651 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15591651 — Biomarker: Interleukin 1 alpha
Type: Safety Biomarker (SAF)
Genes: IL1A; IL1F1
Study 15591651 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 15591651 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8100910 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21872935 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 21872935 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 21872935 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 12546311 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 10051936 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7981577 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23353795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14707020 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7936476 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7936476 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2847567 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26151924 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 23541756 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10027660 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 8746863 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23349882 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 21592048 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 18708299 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 11043056 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27633651 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 25057201 — Biomarker: Auditory steady-state response
Type: Pharmacodynamic Biomarker (PDY)
Study 15678245 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 15678245 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 15678245 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 10037839 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 10037839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8385284 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8385284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29345113 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 22278627 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20507582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15667660 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 12195131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2135068 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6306388 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27711083 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27711083 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27711083 — Biomarker: EGFR
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ERBB1; ERRP
Study 27711083 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 24702135 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22226086 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 8528053 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31856760 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21593283 — Biomarker: SLCO2B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 18073779 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18073779 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11418458 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11418458 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 19735512 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 27348908 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 17980364 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 26786710 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 23241328 — Biomarker: SPHK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPHK1; SK1; SPHK; SPK
Study 3960242 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3960242 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29555665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24999799 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22884058 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31574157 — Biomarker: DSP mRNA
Type: Predictive Biomarker (PRD)
Genes: DSP
Study 31248390 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 28347919 — Biomarker: ATG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATG3; APG3; APG3L
Study 28347919 — Biomarker: UVRAG mRNA
Type: Predictive Biomarker (PRD)
Genes: UVRAG
Study 20381654 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19126117 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 14749693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3125352 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 23593205 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 24128861 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 24128861 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 16508640 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 14631835 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 14631835 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14631835 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8436780 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26184986 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25236509 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 30900194 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 28544071 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 17404163 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17404163 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7554709 — Biomarker: MAOB mRNA
Type: Predictive Biomarker (PRD)
Genes: MAOB
Study 7797748 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26242730 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24217313 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12720535 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 3513531 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24601174 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 24601174 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12730857 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12730857 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 25609562 — Biomarker: TEF mRNA
Type: Predictive Biomarker (PRD)
Genes: TEF; KIAA1655
Study 18498809 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 18498809 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 18498809 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 18498809 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 18498809 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 10648376 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 26597598 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 1360145 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27052530 — Biomarker: ABCG5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG5
Study 27052530 — Biomarker: DHCR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: DHCR7; D7SR