AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 2140346 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30652973 — Biomarker: P4HB mRNA
Type: Predictive Biomarker (PRD)
Genes: P4HB; ERBA2L; PDI; PDIA1; PO4DB
Study 30652973 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28912129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17581195 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 17581195 — Biomarker: CCR3 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CCR3; CMKBR3
Study 17581195 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 15363825 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9387298 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 29851998 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31485457 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31485457 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17521300 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 17521300 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 17521300 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 17521300 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 17521300 — Biomarker: CYP2E1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2E1; CYP2E
Study 15363813 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15363813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7577850 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7033744 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15573713 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15573713 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27603954 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24620447 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22503212 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 22503212 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9663484 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 9663484 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9663484 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9663484 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 2883990 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21486801 — Biomarker: NANOS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS3; NOS3
Study 16916336 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15518756 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23419987 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17184491 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 11864854 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 465276 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24356622 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 24356622 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 15619071 — Biomarker: FABP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FABP4
Study 15619071 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 15619071 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 24714934 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18027255 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 30678709 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18701270 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 18701270 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18701270 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 8139136 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3524181 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28589472 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20076850 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15821396 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 8577017 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8577017 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31950384 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31950384 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 30771790 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 30771790 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 30771790 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 28166118 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12556011 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12556011 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 8849475 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31278280 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25497362 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 20031380 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20031380 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12226038 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 2670019 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2670019 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2670019 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 2670019 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 2670019 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 2670019 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 29710336 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 29710336 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25247897 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16114087 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16114087 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 31280470 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19896082 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 28393633 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 18420099 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18420099 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18420099 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17063993 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 20416290 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 29800466 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9019639 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9019639 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 9019639 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9019639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28264983 — Biomarker: PAG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAG1; CBP; PAG
Study 7863489 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 11090727 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9180665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31972657 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 29803816 — Biomarker: MNT mRNA
Type: Predictive Biomarker (PRD)
Genes: MNT; BHLHD3; ROX
Study 18041735 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 8625493 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 8625493 — Biomarker: CYP2E1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2E1; CYP2E
Study 3894277 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 16729229 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16729229 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 7801618 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 21770897 — Biomarker: CYBB mRNA
Type: Predictive Biomarker (PRD)
Genes: CYBB; NOX2
Study 21770897 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 19716456 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 11059223 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 22995802 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22995802 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19080096 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 3550098 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21914062 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 19783710 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 27704313 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20457540 — Biomarker: CYP19A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 10560994 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 11102590 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 8165591 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 3080694 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 28628707 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22466697 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16815137 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16815137 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16815137 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 29703978 — Biomarker: MYRF mRNA
Type: Predictive Biomarker (PRD)
Genes: MYRF; C11orf9; KIAA0954; MRF
Study 23857798 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 17361524 — Biomarker: CBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CBX1; CBX
Study 17361524 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 1725447 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 1725447 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6617205 — Biomarker: ELK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELK3; NET; SAP2
Study 30719589 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30719589 — Biomarker: New morphometric vertebral fractures
Type: Surrogate Endpoint (SUR)
Study 24703722 — Biomarker: CD6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD6
Study 19775046 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11148432 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 9517944 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26253568 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26253568 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21300709 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11772239 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 11772239 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 11772239 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 26343780 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 21701326 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 19225210 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15650459 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15650459 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 23725518 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18328360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31072395 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29949494 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 26176644 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31257405 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29134891 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15943824 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15943824 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 8722350 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 6362846 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 31201197 — Biomarker: TICAM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TICAM2; TIRAP3; TIRP; TRAM
Study 20497522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2563314 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10678500 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30689703 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29031002 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29031002 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29031002 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27920508 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2233283 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 20180330 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 18220025 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18220025 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18220025 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21413846 — Biomarker: COPE mRNA
Type: Predictive Biomarker (PRD)
Genes: COPE
Study 11158283 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8421475 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8421475 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 31702047 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22176029 — Biomarker: DSPP mRNA
Type: Predictive Biomarker (PRD)
Genes: DSPP
Study 22176029 — Biomarker: DMP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DMP1
Study 22176029 — Biomarker: GAPDH mRNA
Type: Predictive Biomarker (PRD)
Genes: GAPDH; GAPD; CDABP0047; OK/SW-cl.12
Study 12594304 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11783226 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27876583 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 21897859 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 8310507 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 24457911 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23307525 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19032914 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16204287 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study 8099978 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29767793 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 29767793 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 29767793 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 29767793 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 29767793 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18671864 — Biomarker: LTB4R mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 15941372 — Biomarker: STC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STC1; STC
Study 25940724 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 25940724 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24015698 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17094387 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 29078256 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27580595 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 15672210 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10048795 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 10048795 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 10048795 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 10048795 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 6360689 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29140444 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study 24768130 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 19709893 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8946434 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 8946434 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 2014928 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30935317 — Biomarker: MMD mRNA
Type: Predictive Biomarker (PRD)
Genes: MMD; PAQR11
Study 1778878 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29945396 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 12627352 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10487307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1321194 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29693035 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15711607 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 15711607 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19143666 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 15200755 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23321403 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23321403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12173800 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7614501 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 7614501 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 29267553 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 24052035 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10401023 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)