AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31549625 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8986929 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27080318 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 18486458 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24347430 — Biomarker: Carbonic anhydrase IX
Type: Predictive Biomarker (PRD)
Genes: CA9; G250; MN
Study 24347430 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 17520382 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 15122056 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 15122056 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 15122056 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15122056 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15122056 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 9846800 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 21320923 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21320923 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study 12215593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28296334 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 28296334 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 25220215 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 25220215 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 23298335 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23298335 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16865577 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11128344 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11128344 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 11128344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26598744 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 23887684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1609034 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 29544607 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 1975246 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31411768 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26505596 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 22962287 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 6614894 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31083015 — Biomarker: FMOD mRNA
Type: Predictive Biomarker (PRD)
Genes: FMOD; FM; SLRR2E
Study 17701094 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24336012 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 24336012 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23888318 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7837144 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 16483884 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16483884 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10885423 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29695500 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 22928363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15955035 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 31937341 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 30651032 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 30651032 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 17056973 — Biomarker: PTN mRNA
Type: Predictive Biomarker (PRD)
Genes: PTN; HBNF1; NEGF1
Study 10933082 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 18612151 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 8908382 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8908382 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 26803913 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 17548203 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15322742 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7828295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2006662 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 2006662 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29156910 — Biomarker: HS1BP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: HS1BP3
Study 29156910 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 29156910 — Biomarker: Urokinase plasminogen activator surface receptor
Type: Monitoring Biomarker (MOI)
Genes: PLAUR; MO3; UPAR
Study 23884353 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 23884353 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21091270 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11773175 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11773175 — Biomarker: DUSP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DUSP3; VHR
Study 25038874 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23271905 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 23271905 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2966546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2966546 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 21498915 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12684357 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11022850 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23104212 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 23104212 — Biomarker: SMAD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMAD4; DPC4; MADH4
Study 23104212 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 18514618 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9039715 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2579801 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 2579801 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 22897901 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11498311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10884648 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 10884648 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9605251 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 28161387 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 23451243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1413847 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 1413847 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 31497011 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 31497011 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 31497011 — Biomarker: Complement factor D
Type: Safety Biomarker (SAF)
Genes: CFD; DF; PFD
Study 26935357 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26935357 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20634754 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15780117 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12372680 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12372680 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11887892 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11887892 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 11887892 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29606547 — Biomarker: NAPA mRNA
Type: Predictive Biomarker (PRD)
Genes: NAPA; SNAPA
Study 21511276 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17199766 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17199766 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10979640 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1593573 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1593573 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 25249697 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 16928714 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 16119522 — Biomarker: Urinary total protein
Type: Safety Biomarker (SAF)
Study 12108850 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 12108850 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7547016 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24956042 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 941075 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28793042 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28793042 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28793042 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21623465 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21623465 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8998256 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22363056 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 19952403 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19952403 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 19952403 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 16613264 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16613264 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 16613264 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 16613264 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 16613264 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 24080287 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 25794203 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22230406 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22230406 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19799138 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11096006 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 4055985 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21826881 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 17093155 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14687901 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14687901 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 9028935 — Biomarker: ETV6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV6; TEL; TEL1
Study 21590739 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19100110 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 16540953 — Biomarker: CENPJ mRNA
Type: Predictive Biomarker (PRD)
Genes: CENPJ; CPAP; LAP; LIP1
Study 8881951 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 1411281 — Biomarker: FGFR1
Type: Predictive Biomarker (PRD)
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 27535783 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 27535783 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 24958563 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 22678051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11319711 — Biomarker: MMD mRNA
Type: Predictive Biomarker (PRD)
Genes: MMD; PAQR11
Study 22540417 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 4911774 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31709970 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 19276838 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11485076 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 6108780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28343975 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26430724 — Biomarker: INPP5F mRNA
Type: Predictive Biomarker (PRD)
Genes: INPP5F; KIAA0966; SAC2; MSTP007; MSTP047
Study 26430724 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 16102623 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 16102623 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16102623 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 1462277 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15723869 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15723869 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9866433 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17156591 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29168427 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29168427 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24729102 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24729102 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 21106264 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15768050 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 12465429 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29380013 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23435876 — Biomarker: CYP24A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP24A1; CYP24
Study 18458207 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 14990264 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9052890 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9052890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7639352 — Biomarker: PCLAF mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 23010608 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21781652 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15961217 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 30113633 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22648836 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22648836 — Biomarker: LTB mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB; TNFC; TNFSF3
Study 14564334 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10981255 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 8888380 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24509027 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11131271 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11131271 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 11131271 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11131271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1433739 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25223172 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 17679728 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17679728 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 29045529 — Biomarker: MKNK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MKNK1; MNK1
Study 15310780 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7945617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25537011 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 25537011 — Biomarker: Beta-secretase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: BACE1; BACE; KIAA1149
Study 12826500 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28629243 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 27232378 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 27232378 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 12656935 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 12656935 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 12656935 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 12656935 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8739020 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8739020 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22257685 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22257685 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22257685 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22257685 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 21743374 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 11400186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24944136 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12882850 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10995003 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10995003 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 10995003 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 8630632 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24752311 — Biomarker: PAX4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAX4
Study 21741883 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 6144241 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31738483 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18632258 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28626140 — Biomarker: ABCC6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC6; ARA; MRP6
Study 17140552 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17140552 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 17140552 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 6103680 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27751654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21135204 — Biomarker: SLC2A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A1; GLUT1
Study 17369118 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8775569 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21