AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 16189291 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 31133472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23019948 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 20404423 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20404423 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20404423 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20404423 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20404423 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 9785761 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27391857 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27391857 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 2951826 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28231078 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28231078 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 28231078 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18065202 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16253974 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1906239 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 24929624 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8550252 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 6133104 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30381311 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 29129600 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17669707 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11893781 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11893781 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30948254 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28257752 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 25981401 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 25981401 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11323730 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9468460 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29174109 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21092137 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 29962050 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 29962050 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24884501 — Biomarker: FCGR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR2A; CD32; FCG2; FCGR2A1; IGFR2
Study 24884501 — Biomarker: FCGR3A mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 24884501 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 15963119 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 11393207 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29753374 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29753374 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27124410 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27124410 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 21360537 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 21360537 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 21299684 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 14740177 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 24488582 — Biomarker: LYN mRNA
Type: Predictive Biomarker (PRD)
Genes: LYN; JTK8
Study 23082173 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24901128 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17015055 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 14523294 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27116921 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19512937 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19512937 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19512937 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26398184 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 18054420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10996361 — Biomarker: TGFB1
Type: Safety Biomarker (SAF)
Genes: CED; TGFbeta
Study 29133365 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25346026 — Biomarker: PCSK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK5; PC5; PC6
Study 19667500 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 1771401 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30686103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30686103 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26881208 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22095057 — Biomarker: BSG mRNA
Type: Predictive Biomarker (PRD)
Genes: BSG; UNQ6505/PRO21383
Study 18047925 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18047925 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12395333 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25641925 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 22092962 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 7930726 — Biomarker: FCGR2A
Type: Predictive Biomarker (PRD)
Genes: CD32; CD32A; IGFR2; CDw32; Fc-gamma-RIIa; FcgammaRIIa
Study 6415735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20953746 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 11296939 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 4776883 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 28293624 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1438110 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3914805 — Biomarker: RAPGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 1712206 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 2871818 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26719492 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 10950051 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20880642 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 2474109 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2474109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19745175 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 26910108 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 25135744 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 28826727 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 26764322 — Biomarker: CENPJ mRNA
Type: Predictive Biomarker (PRD)
Genes: CENPJ; CPAP; LAP; LIP1
Study 15514725 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2805771 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1103708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21825259 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 16700816 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31732485 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10671664 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 9174182 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 8642235 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6375329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22901557 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24372304 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 24372304 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16125536 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16125536 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16125536 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7496561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21488802 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 21488802 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 6209506 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22071199 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18563969 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 16018851 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10335764 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10335764 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27895542 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27895542 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12037657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25772548 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 11696916 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11967825 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29748907 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 29748907 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 29748907 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 29748907 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 24670828 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 12127382 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9667590 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 9667590 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9667590 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 30508156 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 30508156 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 30508156 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30508156 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 30508156 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 17109685 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12915289 — Biomarker: CDS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDS1; CDS
Study 8776187 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 8776187 — Biomarker: NELFCD mRNA
Type: Predictive Biomarker (PRD)
Genes: NELFCD; NELFD; TH1; TH1L; HSPC130
Study 27491533 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 26591355 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20506254 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 9243044 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19933822 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 24063860 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9301442 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 8359098 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23725851 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 23725851 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23725851 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 23725851 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 19040589 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19040589 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21974764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11867177 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 9517989 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14595471 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 1680135 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1680135 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 1680135 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15552533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11208882 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 11208882 — Biomarker: Cyclin-dependent kinase inhibitor 1
Type: Safety Biomarker (SAF)
Genes: CDKN1A
Study 12482798 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30049849 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 2340539 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 2340539 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 7282615 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 22568178 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10102254 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10102254 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22155531 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 9360028 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3009050 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 12937228 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12937228 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12937228 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12937228 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 27755159 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 27755159 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 24148194 — Biomarker: PDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PDK4; PDHK4
Study 20542963 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19288904 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 17054466 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 12576315 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12576315 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 7933324 — Biomarker: Major prion protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRNP; ALTPRP; PRIP; PRP
Study 3064604 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29520889 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29520889 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2204432 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 31812472 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 21812357 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19376184 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 16434589 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 6336600 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6336600 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 6336600 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 29467885 — Biomarker: NDP mRNA
Type: Predictive Biomarker (PRD)
Genes: NDP; EVR2
Study 17171884 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 29581202 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 18178097 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 18178097 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18178097 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 18178097 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12640085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28169885 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17578859 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 17578859 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 17578859 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 24498399 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18219959 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11940545 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2693918 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2693918 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25627186 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study 30967597 — Biomarker: CYP19A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 30967597 — Biomarker: UGT2B17 mRNA
Type: Predictive Biomarker (PRD)
Genes: UGT2B17
Study 30967597 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28697504 — Biomarker: PLXNB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLXNB1; KIAA0407; PLXN5; SEP
Study 23627832 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1694945 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1694945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 41475 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23870127 — Biomarker: GPSM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPSM2; LGN
Study 22613099 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 12787319 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 10918646 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8872727 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31479116 — Biomarker: LAMB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMB2; LAMS
Study 8092094 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21412424 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19110158 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17227995 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9736420 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 7914888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 779390 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31981777 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 18037776 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18037776 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 18037776 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 16116345 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 16116345 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2