AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23175769 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19047814 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 8478043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1831083 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 7066289 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30586691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17489898 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 30987917 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 25698492 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25698492 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11526203 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17443000 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 17443000 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31461400 — Biomarker: CDON mRNA
Type: Predictive Biomarker (PRD)
Genes: CDON; CDO
Study 21314329 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 21314329 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14604059 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 29767728 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 25252254 — Biomarker: NBN mRNA
Type: Predictive Biomarker (PRD)
Genes: NBN; NBS; NBS1; P95
Study 15747897 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 24256097 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14984435 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22563210 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 7589012 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 7146823 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 7146823 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 26508309 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 22131224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18419350 — Biomarker: HFE mRNA
Type: Predictive Biomarker (PRD)
Genes: HFE; HLAH
Study 8665532 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 22331954 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16973657 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15815820 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11223695 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7896386 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 3630961 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26043884 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19190553 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 15313947 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8935811 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 10331442 — Biomarker: CLTB mRNA
Type: Predictive Biomarker (PRD)
Genes: CLTB
Study 10331442 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21873710 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18640686 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10230950 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10230950 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 10230950 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 31087200 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21658141 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 23167953 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21706269 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 21706269 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21706269 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8640163 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30297397 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 26358120 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22451451 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 22451451 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 19121416 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31977865 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31977865 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 31977865 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 23921860 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 26252526 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 26252526 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11479157 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 11479157 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11479157 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 11751721 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3327654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30165438 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 23996969 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 22330261 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 9638984 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 30951497 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26313133 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 26313133 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 8757381 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8757381 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8757381 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8757381 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1682907 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6807681 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 27358067 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 22990854 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22990854 — Biomarker: Plasma sitosterol and campesterol
Type: Surrogate Endpoint (SUR)
Study 17201457 — Biomarker: SLC35A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC35A2; UGALT; UGT; UGTL
Study 17201457 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16263350 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31241992 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31241992 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 31241362 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31241362 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28472976 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 28472976 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 9375889 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3929513 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 25763921 — Biomarker: UST mRNA
Type: Predictive Biomarker (PRD)
Genes: UST; DS2ST
Study 23736807 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16395725 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 16395725 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11564035 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 7817797 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25263372 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19274909 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 30761523 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 30761523 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 23264537 — Biomarker: SLC16A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC16A4; MCT4; MCT5
Study 23264537 — Biomarker: MCTS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCTS1; MCT1
Study 19035876 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10225812 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8876346 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 8876346 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 29498469 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 29498469 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 26888258 — Biomarker: PGR mRNA
Type: Predictive Biomarker (PRD)
Genes: PGR; NR3C3
Study 7658599 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 791331 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21982529 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14661817 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3884122 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3884122 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 20033907 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 26383695 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 24126796 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 21788373 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 15855970 — Biomarker: HGD mRNA
Type: Predictive Biomarker (PRD)
Genes: HGD; HGO
Study 11932564 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29978417 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10636265 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10636265 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 10636265 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31433919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9422295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15911730 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15911730 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27164866 — Biomarker: PICALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PICALM; CALM
Study 12058997 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 9862248 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9862248 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27027462 — Biomarker: KCNJ6 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNJ6; GIRK2; KATP2; KCNJ7
Study 27027462 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 22921680 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 18503929 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 18503929 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 30739911 — Biomarker: STK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: STK4; KRS2; MST1
Study 24613543 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22384088 — Biomarker: STAT5A mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT5A; STAT5
Study 18251141 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15734253 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 29046015 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25929192 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16899830 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 7841973 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7841973 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3180489 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18771605 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 31753727 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27073205 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27073205 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12919710 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9004094 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24581948 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24581948 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15730052 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10911770 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 28276743 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15369420 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15369420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15369420 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11514487 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9344704 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9344704 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 9344704 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 9344704 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 9344704 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 9344704 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22721873 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11060814 — Biomarker: GCSAM mRNA
Type: Predictive Biomarker (PRD)
Genes: GCSAM; GAL; GCET2
Study 1484852 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25168098 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 19293693 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22404431 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22404431 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 20515418 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18541083 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 10486670 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25670364 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 25670364 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25670364 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23033926 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 23033926 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23033926 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 25765965 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21784351 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 18027048 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 18027048 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18027048 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7991068 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 17124720 — Biomarker: HSPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPD1; HSP60
Study 31971279 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31971279 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 30585257 — Biomarker: UGT1A1
Type: Safety Biomarker (SAF)
Genes: UGT1A
Study 25980699 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22068444 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7777109 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2131899 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30878623 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15257742 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 30851442 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 24301237 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 30358109 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30358109 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30358109 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 30358109 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30358109 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 19058981 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6849746 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31344451 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 31344451 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23886675 — Biomarker: SV2C mRNA
Type: Predictive Biomarker (PRD)
Genes: SV2C; KIAA1054
Study 17909087 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 29325658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27695785 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 22033034 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 11593504 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 8911885 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31608454 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31608454 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 31608454 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 22159910 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20565296 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 3073868 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 30553700 — Biomarker: Survival motor neuron protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 7700071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)