AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT02434861 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT02434861 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT02434861 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study NCT02434861 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study NCT02434861 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study NCT01434303 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02520791 — Biomarker: ICOS mRNA
Type: Predictive Biomarker (PRD)
Genes: ICOS; AILIM
Study NCT02590081 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01037530 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT03002844 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03465007 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00852618 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study NCT01776294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03237702 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study NCT02965716 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01300637 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT01300637 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01300637 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02733913 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT02809300 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03142646 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT04168619 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01342666 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01847248 — Biomarker: HSPA12B mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA12B; C20orf60
Study NCT00241930 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT01863004 — Biomarker: DYSF mRNA
Type: Predictive Biomarker (PRD)
Genes: DYSF; FER1L1
Study NCT02715063 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01138722 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT03372616 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03626233 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03626233 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study NCT02093533 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study NCT02454244 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02454244 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04293614 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04306926 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00220090 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study NCT03094052 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04388826 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT00001934 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT02437318 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02437318 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT02437318 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study NCT02437318 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT03851705 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study NCT03851705 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01066845 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT01066845 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00641381 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04180267 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03243461 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03781063 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT03979651 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study NCT04782921 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study NCT00136721 — Biomarker: PINK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PINK1
Study NCT00136721 — Biomarker: Leucine-rich repeat kinase 2
Type: Pharmacodynamic Biomarker (PDY)
Genes: LRRK2; PARK8
Study NCT01086527 — Biomarker: SLCO2B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study NCT00883597 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study NCT01486732 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT02144935 — Biomarker: AFM mRNA
Type: Predictive Biomarker (PRD)
Genes: AFM; ALB2; ALBA
Study NCT03308487 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT03308487 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03308487 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04810884 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03132142 — Biomarker: TPRA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPRA1; GPR175; TMEM227; PP6566
Study NCT03132142 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study NCT00788112 — Biomarker: HDAC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HDAC1; RPD3L1
Study NCT00788112 — Biomarker: HDAC6 mRNA
Type: Predictive Biomarker (PRD)
Genes: HDAC6; KIAA0901; JM21
Study NCT00799565 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study NCT00529048 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT00902044 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00902044 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study NCT03971747 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study NCT03492632 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT01192256 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study NCT02573493 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study NCT02573493 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02573493 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00185341 — Biomarker: CCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR1; CMKBR1; CMKR1; SCYAR1
Study NCT02709343 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT01316666 — Biomarker: NE
Type: Predictive Biomarker (PRD)
Study NCT02503722 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01236989 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study NCT04226469 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study NCT04116684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01787994 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00049543 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT02296125 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00159016 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01435161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03775447 — Biomarker: Leucine-rich repeat kinase 2
Type: Pharmacodynamic Biomarker (PDY)
Genes: LRRK2; PARK8
Study NCT02313844 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT02280655 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04075708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00746811 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT05374616 — Biomarker: TANGO2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TANGO2; C22orf25
Study NCT02057354 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT02057354 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT00768131 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01563055 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT03132467 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03132467 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT03132467 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT02912949 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02912949 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study NCT02912949 — Biomarker: NRG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study NCT02116829 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03369353 — Biomarker: CXADR mRNA
Type: Predictive Biomarker (PRD)
Genes: CXADR; CAR
Study NCT02887313 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study NCT02740270 — Biomarker: TNFRSF18 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF18; AITR; GITR; UNQ319/PRO364
Study NCT00626041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03447873 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04175886 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT04008394 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study NCT01007344 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03227523 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT02580448 — Biomarker: CYP17A1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CYP17A1; CYP17; S17AH
Study NCT03730519 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05967754 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT05967754 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study NCT03955445 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study NCT01581424 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study NCT04033640 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study NCT00683735 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT01749761 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02601053 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT02197858 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00569179 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT02499614 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT02499614 — Biomarker: ROS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROS1; MCF3; ROS
Study NCT02499614 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study NCT01318681 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study NCT00565747 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT02940548 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01459120 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04498546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02974192 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study NCT04768244 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT04089410 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT01636284 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01862003 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01862003 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01862003 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study NCT04023019 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study NCT02867137 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study NCT02867137 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study NCT02183584 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT04435158 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04435158 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT02735200 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study NCT00267176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03093714 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study NCT04069988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03265184 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study NCT03692520 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03744390 — Biomarker: IDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH2
Study NCT00152438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03620396 — Biomarker: Trefoil factor 3
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TFF3; ITF; TFI
Study NCT04630483 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study NCT04630483 — Biomarker: Platelet to lymphocyte
Type: Safety Biomarker (SAF)
Study NCT00175279 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT02752542 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04962854 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03557190 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03557190 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study NCT03497377 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01642888 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT03606577 — Biomarker: Minimal residual disease response rate
Type: Surrogate Endpoint (SUR)
Study NCT02229617 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study NCT00344162 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03379974 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study NCT02418091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02482233 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study NCT06037135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01069549 — Biomarker: AGTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study NCT01069549 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT01069549 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study NCT02862093 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study NCT00095550 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04076033 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03994146 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00806585 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT01109095 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01109095 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study NCT00637910 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03809299 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01924780 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study NCT01071967 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00003604 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT03505099 — Biomarker: Survival motor neuron protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT03755193 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03563547 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study NCT03563547 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02341924 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT02341924 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02341924 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04439266 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT02898948 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study NCT04220359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00961142 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT04520165 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study NCT04520165 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT04520165 — Biomarker: TSLP mRNA
Type: Predictive Biomarker (PRD)
Genes: TSLP
Study NCT04520165 — Biomarker: IL5RA mRNA
Type: Predictive Biomarker (PRD)
Genes: IL5RA; IL5R
Study NCT03467802 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study NCT03089294 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study NCT01276951 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00031733 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00031733 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study NCT00646386 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01968980 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03147456 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT03490994 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT03904160 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03552770 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03552770 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT04546789 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study NCT01897233 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study NCT02594215 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study NCT02520778 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02520778 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study NCT02520778 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00697814 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT05386446 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT04117451 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03313206 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01072357 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01072357 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT03573791 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study NCT03713801 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT00920686 — Biomarker: NXN mRNA
Type: Predictive Biomarker (PRD)
Genes: NXN; NRX
Study NCT02540421 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study NCT04231864 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study NCT04272801 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1