AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 18195160 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 18195160 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 18195160 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 15538568 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 10774589 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30684674 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 26710216 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18594319 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 6616153 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 24080099 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24080099 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 12505543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10508285 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 10508285 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19477400 — Biomarker: SULT1E1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SULT1E1; STE
Study 2397553 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 15713724 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 20876366 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2886822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23009573 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16169319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8671908 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 8671908 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 1660550 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1660550 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26218411 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23159479 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 14586743 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14586743 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10756223 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 1563463 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 1563463 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 23188130 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21194898 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 7905217 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22177374 — Biomarker: POR mRNA
Type: Predictive Biomarker (PRD)
Genes: POR; CYPOR
Study 22177374 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 9247766 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9247766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3568582 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 3568582 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22677046 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22677046 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18618738 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15984601 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 2046054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31171039 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2037703 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31943216 — Biomarker: MALT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MALT1; MLT
Study 31943216 — Biomarker: LTB mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB; TNFC; TNFSF3
Study 31943216 — Biomarker: STAT5A mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT5A; STAT5
Study 26864369 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 17937567 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 15834296 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9425914 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31053945 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31053945 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 24849545 — Biomarker: IGF1R mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1R
Study 8762729 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 8762729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6813952 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 6813952 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 20714138 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 3247253 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 24885921 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22269899 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 18403448 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15813712 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 6139572 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 31797034 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31797034 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 23406994 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19735557 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8422824 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 3568947 — Biomarker: PIR mRNA
Type: Predictive Biomarker (PRD)
Genes: PIR
Study 3568947 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 22682149 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22682149 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 28029063 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25448247 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16537679 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 16296700 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30975584 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 25944854 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19552659 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11462061 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 11462061 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 24759040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16741040 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16741040 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 16741040 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15578258 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 30962676 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study 28850308 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15316335 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10204815 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19293594 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7599447 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19667564 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2057468 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21744011 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 16167254 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16167254 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30998824 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15157383 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8161862 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22366105 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 29637282 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16229114 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10470991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7890074 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27932278 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12140794 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 1053432 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23985254 — Biomarker: CCND1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND1; BCL1; PRAD1
Study 18214709 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2892499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16874157 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16874157 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11015164 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1459387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30109735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30109735 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27504006 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24323034 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 24323034 — Biomarker: TMPRSS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMPRSS2; PRSS10
Study 24323034 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 10611554 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31567943 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 25785452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19106795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15259283 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 22647439 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 19605829 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 17445898 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16113430 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12575211 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 2088462 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 28641642 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 28641642 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 21883103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15221991 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 15221991 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12149107 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2674067 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7618457 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 16238908 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 1769643 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31628482 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26307030 — Biomarker: AHRR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHRR; BHLHE77; KIAA1234
Study 24520101 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24520101 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17767476 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 17767476 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17767476 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12231497 — Biomarker: DEFA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DEFA1; DEF1; DEFA2; MRS; DEFA1B
Study 10100062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6305183 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 6305183 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11726414 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11726414 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9394699 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9394699 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28393781 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28393781 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 10889125 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8957147 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27397441 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27397441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17073850 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16338276 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 16338276 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 16338276 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 7720343 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25753895 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25753895 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23817692 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 9834769 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21945511 — Biomarker: LTB mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB; TNFC; TNFSF3
Study 21945511 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15102865 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2491521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19603054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17338790 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15132303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25589782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30779531 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 20593354 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18372584 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12824978 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8891498 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 31150063 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 30572923 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 23224336 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23224336 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6342359 — Biomarker: TNR mRNA
Type: Predictive Biomarker (PRD)
Genes: TNR
Study 31797710 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 31797710 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16390770 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2668524 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23683667 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 23683667 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 23683667 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10899481 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 8362773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8362773 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30741868 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30741868 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 28965176 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 26676059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20934601 — Biomarker: PRF1
Type: Predictive Biomarker (PRD)
Genes: PFP; P1; HPLH2
Study 15800559 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15800559 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15800559 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12803510 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12803510 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12803510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28806366 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18614724 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15863986 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 15863986 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 489772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21881539 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21881539 — Biomarker: NR1D1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1D1; EAR1; HREV; THRAL
Study 21881539 — Biomarker: NR1D2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1D2
Study 21881539 — Biomarker: PER1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PER1; KIAA0482; PER; RIGUI
Study 21881539 — Biomarker: BMAL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BMAL1; ARNTL; BHLHE5; MOP3; PASD3
Study 14980943 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11686857 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18614981 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 9010698 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 9010698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31356985 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 27812717 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22713768 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22713768 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14522571 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 14522571 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 14522571 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17666472 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 24304551 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26483333 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 23672993 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 18490279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19679578 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 24004887 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12127125 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29698772 — Biomarker: PRKRA mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKRA; PACT; RAX; HSD-14; HSD14
Study 26111129 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 10738706 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 10738706 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 10738706 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 8466728 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3993534 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20731529 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 20731529 — Biomarker: PLTP mRNA
Type: Predictive Biomarker (PRD)
Genes: PLTP
Study 20731529 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)