AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 20210645 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20210645 — Biomarker: CXCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR5; BLR1; MDR15
Study 20210645 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 20210645 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 20214479 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20214479 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 20214479 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 20214479 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20214527 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20214798 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 20219965 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 20221623 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 20225395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20225395 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20228610 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 20228610 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 20233136 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 20233444 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 20233444 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 20233444 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 20233444 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 20233444 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 20233444 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 20233976 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 20236700 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20298558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20298558 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20298564 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20298923 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 20299634 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 20299634 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20307398 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20335221 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 20335221 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 20339536 — Biomarker: CLMN mRNA
Type: Predictive Biomarker (PRD)
Genes: CLMN; KIAA1188
Study 20339536 — Biomarker: APOC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOC1
Study 20339536 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 20345222 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 20347684 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 20350136 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 20350136 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 20350190 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 20350302 — Biomarker: Amyloid beta peptide (1-40)
Type: Pharmacodynamic Biomarker (PDY)
Genes: APP; A4; AD1
Study 20350831 — Biomarker: OPA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: OPA3
Study 20354183 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 20362723 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20368649 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20369375 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 20370777 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20374273 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 20374273 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 20375178 — Biomarker: AQP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP1; CHIP28
Study 20375178 — Biomarker: PLIN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLIN2; ADFP
Study 20375733 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 20378407 — Biomarker: Histone acetylation
Type: Pharmacodynamic Biomarker (PDY)
Study 20378559 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20378927 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 20380712 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 20382691 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 20383216 — Biomarker: BMF mRNA
Type: Predictive Biomarker (PRD)
Genes: BMF
Study 20384962 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 20390419 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20390419 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study 20391423 — Biomarker: SSB mRNA
Type: Predictive Biomarker (PRD)
Genes: SSB
Study 20395557 — Biomarker: SMAD3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMAD3; MADH3
Study 20395557 — Biomarker: HMGA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: HMGA2; HMGIC
Study 20395557 — Biomarker: ACTA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACTA2; ACTSA; ACTVS; GIG46
Study 20395557 — Biomarker: S100A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: S100A4; CAPL; MTS1
Study 20395557 — Biomarker: SFTPC mRNA
Type: Predictive Biomarker (PRD)
Genes: SFTPC; SFTP2
Study 20400682 — Biomarker: WT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WT1
Study 20400682 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20400682 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 20406267 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 20408846 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 20410100 — Biomarker: Clusterin
Type: Safety Biomarker (SAF)
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 20410100 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 20410100 — Biomarker: TNFRSF10B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9; UNQ160/PRO186
Study 20410100 — Biomarker: MSR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MSR1; SCARA1
Study 20413039 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20413436 — Biomarker: PKHD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PKHD1; FCYT; TIGM1
Study 20413658 — Biomarker: WT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WT1
Study 20413658 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 20413687 — Biomarker: DHODH mRNA
Type: Predictive Biomarker (PRD)
Genes: DHODH
Study 20413733 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 20413733 — Biomarker: HMGCR mRNA
Type: Predictive Biomarker (PRD)
Genes: HMGCR
Study 20418798 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20420675 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 20420675 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20421061 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20421061 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 20421061 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20421452 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 20421455 — Biomarker: IDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH2
Study 20421455 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 20422738 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20424554 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20424554 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 20427509 — Biomarker: UCP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP2; SLC25A8
Study 20427701 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 20429821 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 20430469 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20430905 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 20431360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20432813 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 20432813 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 20433539 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20433546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20435200 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 20435659 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20439622 — Biomarker: CCL18 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 20439622 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20439622 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20442368 — Biomarker: WT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WT1
Study 20442368 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 20442368 — Biomarker: CD96 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD96
Study 20442368 — Biomarker: SNRPN mRNA
Type: Predictive Biomarker (PRD)
Genes: SNRPN; HCERN3; SMN
Study 20442368 — Biomarker: INSR mRNA
Type: Predictive Biomarker (PRD)
Genes: INSR
Study 20442368 — Biomarker: IRS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRS2
Study 20442368 — Biomarker: PRKAA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKAA1; AMPK1
Study 20442368 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20442365 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 20442365 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20442365 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20444270 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20446946 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 20446946 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20446946 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 20447528 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 20447528 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20448073 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 20448073 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 20448094 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20457766 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 20457766 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 20457975 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20458050 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20458050 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20458050 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 20458050 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 20458532 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 20461780 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20463041 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20463041 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20463041 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20466783 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20471725 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20471725 — Biomarker: T-cell specific protein RANTES
Type: Safety Biomarker (SAF)
Genes: CCL5; D17S136E; SCYA5
Study 20472746 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20472746 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20478057 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20478057 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20484443 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20484485 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 20487048 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 20489056 — Biomarker: AIRE mRNA
Type: Predictive Biomarker (PRD)
Genes: AIRE; APECED
Study 20489620 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 20489620 — Biomarker: PDGFRA mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 20491780 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study 20501469 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 20507945 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20510210 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 20511445 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20511662 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 20519658 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 20519658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20519661 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 20521331 — Biomarker: SRM mRNA
Type: Predictive Biomarker (PRD)
Genes: SRM; SPS1; SRML1
Study 20524979 — Biomarker: LTBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LTBP1
Study 20528299 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 20529243 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20529243 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20529243 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20530034 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 20530034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20530034 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 20530048 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 20534736 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 20538956 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 20545713 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20546561 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20547978 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20547978 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 20547978 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20550691 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20550701 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20550701 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20553600 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20557308 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 20558556 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 20559034 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20560883 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20562120 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20564750 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20564750 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20566896 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20573151 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 20581689 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20581689 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20585012 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 20585012 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20597081 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 20597081 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 20598843 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 20599337 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20605360 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 20608766 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 20609468 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 20609468 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 20609706 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20616163 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 20620717 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 20625116 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 20625116 — Biomarker: IDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH2
Study 20625390 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20627920 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 20630061 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 20630061 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 20630061 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 20633428 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 20634483 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20634719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20634785 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20634785 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 20638196 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 20647561 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20650435 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5