AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 20583949 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 12527674 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 8898763 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6325994 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30476104 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30476104 — Biomarker: POMC mRNA
Type: Predictive Biomarker (PRD)
Genes: POMC
Study 30476104 — Biomarker: CYB5A mRNA
Type: Predictive Biomarker (PRD)
Genes: CYB5A; CYB5
Study 30476104 — Biomarker: FURIN mRNA
Type: Predictive Biomarker (PRD)
Genes: FURIN; FUR; PACE; PCSK3
Study 30476104 — Biomarker: GPX4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPX4
Study 30476104 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 30476104 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 30476104 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 30476104 — Biomarker: PCSK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK2; NEC2
Study 22840353 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 19792989 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 17719559 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11345374 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 21613310 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21613310 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16958291 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 15193480 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 9373765 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 30833486 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 20662716 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20662716 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12172314 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7605708 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31577041 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19683429 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19317165 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19317165 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1879030 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26503370 — Biomarker: MHC class I polypeptide-related sequence A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MICA; PERB11.1
Study 23317171 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8110564 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 8110564 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28784453 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11186221 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11186221 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28329315 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 28329315 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 20924095 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12409965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12409965 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12409965 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16796078 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 16796078 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16796078 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11259986 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 3103158 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19473822 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19473822 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 19473822 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7272178 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31036468 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31036468 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31036468 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 21884007 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19538242 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 10598600 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25180876 — Biomarker: NFIC mRNA
Type: Predictive Biomarker (PRD)
Genes: NFIC; NFI
Study 22056021 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 21123578 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 17613279 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17613279 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12005153 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 26162521 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15502721 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15502721 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11684376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7888289 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3285878 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28537581 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28537581 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25380149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20197560 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 12732395 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12732395 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12732395 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12732395 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10372217 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 10372217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9082342 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 27348904 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17950182 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20389106 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 2059758 — Biomarker: CD6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD6
Study 6851564 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 28229275 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 20962623 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20962623 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 22695185 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 22695185 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 11726264 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11421505 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15177518 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30974993 — Biomarker: NES mRNA
Type: Predictive Biomarker (PRD)
Genes: NES; Nbla00170
Study 25201887 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17062648 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 10493673 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 8757423 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19589010 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19589010 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 7713273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28902127 — Biomarker: MZB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MZB1; MEDA7; PACAP; HSPC190
Study 23708326 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23708326 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9041098 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9041098 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30431378 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9238624 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9238624 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11253316 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 11281052 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19548439 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 19548439 — Biomarker: TIMM8A mRNA
Type: Predictive Biomarker (PRD)
Genes: TIMM8A; DDP; DDP1; TIM8A
Study 19548439 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19548439 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31303147 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31303147 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 31303147 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26756114 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26756114 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15848577 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7597378 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28847152 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23890317 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11915777 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7908501 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31647139 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 29232314 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 20584129 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 27560676 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 19875309 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15642550 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15642550 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19283791 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17616536 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 17616536 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15775731 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 30219249 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30219249 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3591604 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21118366 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 10793878 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9387527 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 27287856 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 12571693 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23348933 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7640328 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 31809601 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28234053 — Biomarker: PTGDR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 25980351 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 23963546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17877953 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15753494 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2548548 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2548548 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27410480 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27410480 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8562975 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8562975 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8562975 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8562975 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17955229 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 17955229 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8701878 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6636913 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 27734232 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17954173 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 17954173 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11825344 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11825344 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9828635 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 30851066 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16963035 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 1518122 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 27278933 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26637482 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16540840 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16540840 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12959740 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 12959740 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 30304141 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22309404 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26178495 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26178495 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26178495 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17581594 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9445498 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 31132978 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31132978 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19057451 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11597377 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9816659 — Biomarker: PTGDS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGDS; PDS
Study 26080850 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23010883 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12529661 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 30585388 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 18390968 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 18390968 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 18390968 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 24996807 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17692153 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 17692153 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26647373 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 24961493 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24961493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2617243 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 28159196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23076431 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15799170 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15799170 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15799170 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23583566 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 23577078 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 18547996 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18547996 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31331699 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31331699 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 31331699 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 18654123 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11310690 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31206225 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31206225 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23791894 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 14528504 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22859346 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8885114 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 27056776 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 17908710 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 8317392 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23090161 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12200985 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP