AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 8748192 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7282519 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26098004 — Biomarker: CGAS mRNA
Type: Predictive Biomarker (PRD)
Genes: CGAS; C6orf150; MB21D1
Study 23535987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2532458 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22746542 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6146164 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 29970184 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 30835956 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 15681524 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 15681524 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12017317 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 12017317 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 3094 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3094 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 28403018 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3517076 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28421628 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28421628 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 25550228 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 16202394 — Biomarker: NOS1AP mRNA
Type: Predictive Biomarker (PRD)
Genes: NOS1AP; CAPON; KIAA0464
Study 10541929 — Biomarker: Succinate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: SDHD
Study 21290835 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15767642 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25677920 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22791802 — Biomarker: MEA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MEA1; MEA
Study 22791802 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 23874575 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21267804 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16902841 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 26213156 — Biomarker: SLCO2B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 20546945 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12559781 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 12559781 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 1659189 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30745183 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 30742122 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 23499440 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 16758944 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 16758944 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16758944 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 16758944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15089784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11274311 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 11274311 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11274311 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9278199 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 8350363 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 15262458 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29951915 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25221948 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28834259 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26291335 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 21188521 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 21188521 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18334913 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 18334913 — Biomarker: Cholinesterase
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: BCHE; CHE1
Study 20016927 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 15562907 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 11329798 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 7962672 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26171380 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21812891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16623961 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 25782319 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23059151 — Biomarker: TREH mRNA
Type: Predictive Biomarker (PRD)
Genes: TREH; TREA
Study 17568325 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27561823 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 23002126 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18171294 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18171294 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 10764713 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 25898404 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29652273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20045196 — Biomarker: HTR2C mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2C; HTR1C
Study 16926775 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10769437 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 10769437 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8315266 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22693269 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1958764 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 20519962 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 20519962 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10435374 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 10435374 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 10435374 — Biomarker: TET1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET1; CXXC6; KIAA1676; LCX
Study 7482625 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7482625 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 6135874 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 27592180 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 20426913 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9590494 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 22175429 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 21046773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15891319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1989427 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11349937 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9589236 — Biomarker: Insulin receptor substrate 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IRS1
Study 15141270 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12972969 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12972969 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12972969 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 1829368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23682433 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18580415 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17823083 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17823083 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16200917 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16200917 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 27557302 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 29471865 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27177316 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28779304 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study 7928850 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 28637922 — Biomarker: CFI mRNA
Type: Predictive Biomarker (PRD)
Genes: CFI; IF
Study 28637922 — Biomarker: Complement factor D
Type: Safety Biomarker (SAF)
Genes: CFD; DF; PFD
Study 15758246 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15758246 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18482144 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9010373 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 8093291 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28741134 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 17284750 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 16124970 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25885280 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19665588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19139391 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16086932 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 282069 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21562092 — Biomarker: ADIPOQ mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 14711021 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30052729 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 23627026 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12458653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29796934 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 20937186 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1971991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 375690 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 29857165 — Biomarker: DDN mRNA
Type: Predictive Biomarker (PRD)
Genes: DDN; KIAA0749
Study 28279168 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 25885732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11336164 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11336164 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30581161 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 26160997 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 8624267 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 23964387 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18928387 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9088811 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3528891 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 3528891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29737802 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29737802 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27130723 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 15685254 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 29655971 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19223546 — Biomarker: CYP1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A1
Study 19223546 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 19223546 — Biomarker: CYP1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1B1
Study 19223546 — Biomarker: GSTA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTA1
Study 19223546 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 19223546 — Biomarker: GSTM3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM3; GST5
Study 19223546 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 19223546 — Biomarker: SULT1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SULT1A1; STP; STP1; OK/SW-cl.88
Study 19223546 — Biomarker: SULT1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SULT1A2; STP2
Study 21511219 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 8309562 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 2468912 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25898343 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 20939913 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20939913 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6148312 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27644138 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 9247510 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27840374 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10853566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2312774 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 2312774 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 22534669 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 12952837 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 2073484 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 6366148 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 10025472 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27623133 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 21903893 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 25683748 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23808298 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12963561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30892820 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30892820 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 27117038 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23525418 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 12851527 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 2830968 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31937915 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28277432 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28277432 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 21744744 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 30123970 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 30123970 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 30123970 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30123970 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30123970 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 1352828 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6371693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30021759 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 24577847 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 28595236 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 25217488 — Biomarker: MPG mRNA
Type: Predictive Biomarker (PRD)
Genes: MPG; AAG; ANPG; MID1
Study 1636917 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22865603 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 22865603 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22865603 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14602215 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 10912657 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 30790160 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 25083614 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17077928 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9186381 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 3880687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30209858 — Biomarker: ADH1B mRNA
Type: Predictive Biomarker (PRD)
Genes: ADH1B; ADH2
Study 25644856 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31319234 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15326084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31773165 — Biomarker: A2M mRNA
Type: Predictive Biomarker (PRD)
Genes: A2M; CPAMD5; FWP007
Study 25823768 — Biomarker: TYRO3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TYRO3; BYK; DTK; RSE; SKY; TIF
Study 16625008 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7959537 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23897949 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 6704647 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30364933 — Biomarker: POU4F1 mRNA
Type: Predictive Biomarker (PRD)
Genes: POU4F1; BRN3A; RDC1
Study 30364933 — Biomarker: MCM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCM2; BM28; CCNL1; CDCL1; KIAA0030
Study 30364933 — Biomarker: SMC1B mRNA
Type: Predictive Biomarker (PRD)
Genes: SMC1B; SMC1L2
Study 30364933 — Biomarker: CXCL6 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL6; GCP2; SCYB6
Study 30364933 — Biomarker: MMP12 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP12; HME
Study 30364933 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 17095559 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 2782273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 786662 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15464333 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 15464333 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 2690225 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2690225 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 17923591 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17923591 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17923591 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 2109531 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 7324924 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30312135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24112444 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 24112444 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21857901 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29249774 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19094535 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 25707 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25707 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)