AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 17986525 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10524687 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 8523876 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29723896 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 28182863 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9605897 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2608693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18446392 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29310653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9568553 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3055074 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30715100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28398499 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 28398499 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 15295613 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15295613 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11306743 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 26030423 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 26030423 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 26030423 — Biomarker: NKRF mRNA
Type: Predictive Biomarker (PRD)
Genes: NKRF; ITBA4; NRF
Study 23562361 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19622708 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15582080 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 29301585 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 21792863 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17244770 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 7894551 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31618863 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 27829249 — Biomarker: TNFRSF6B
Type: Predictive Biomarker (PRD)
Genes: DcR3; DCR3; TR6; M68
Study 27829249 — Biomarker: Trefoil factor 3
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TFF3; ITF; TFI
Study 21673045 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 19843683 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 2439808 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2439808 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29861725 — Biomarker: Angiopoietin-related protein 4
Type: Predictive Biomarker (PRD)
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 15987865 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7546498 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7546498 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 43950 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28618005 — Biomarker: Beta-secretase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: BACE1; BACE; KIAA1149
Study 25243731 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23534542 — Biomarker: miR-122
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR122
Study 16519546 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30101300 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20646599 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18700689 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12418497 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 31804580 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31804580 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16969894 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 5411446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2790695 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30796973 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 27557955 — Biomarker: MIA mRNA
Type: Predictive Biomarker (PRD)
Genes: MIA
Study 23825422 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 23825422 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 21707983 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23595408 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 17043614 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 9249230 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9249230 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29505744 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 18035196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 327758 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 20101512 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20101512 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10421219 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10421219 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26574566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9564795 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9564795 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2275909 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25828038 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21434334 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 15231854 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 31714573 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22480099 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9786163 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 9786163 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25545196 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 20875492 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20875492 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 16824833 — Biomarker: ACAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAT1; ACAT; MAT
Study 29984912 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19385713 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 2096487 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 2096487 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 361201 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 24267042 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24267042 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24267042 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28592386 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28592386 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 1316885 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20108040 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29896813 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29896813 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 29896813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27289122 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22089534 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20435205 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17368974 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10485423 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 17573736 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6734051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31490959 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31490959 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29297472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27141838 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 21313901 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 28739766 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 23161902 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21606190 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21050483 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14741065 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8406655 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23095630 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 15896585 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12169868 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12169868 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12169868 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9802752 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 9802752 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 31227804 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 31227804 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31227804 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27461166 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 27461166 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 10595697 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28887907 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 22249353 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 16128596 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 16128596 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 16128596 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 10194083 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8789567 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 8789567 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 6803692 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 6803692 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 6803692 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 17822748 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 2871952 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 31127363 — Biomarker: CTLA4
Type: Predictive Biomarker (PRD)
Genes: CD152; CD; GSE; CTLA-4
Study 15041612 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9006882 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9006882 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 9006882 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8485071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30298202 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30298202 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16300166 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 2508850 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31845191 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 31845191 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 28483015 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 15316867 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 4006240 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22025606 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 1384845 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 26772193 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26772193 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 18509786 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 18509786 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 18509786 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9609358 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 2797920 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25275318 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 25275318 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 25275318 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25275318 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17978591 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17978591 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9627359 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9627359 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26848570 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26848570 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 26472571 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22078985 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29117576 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 16115731 — Biomarker: Leucine-rich repeat kinase 2
Type: Pharmacodynamic Biomarker (PDY)
Genes: LRRK2; PARK8
Study 12106929 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 2555105 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 2555105 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2555105 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 10694109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1912554 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 17543680 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 17543680 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 28843974 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26836910 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 10425301 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2138974 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 111275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30615024 — Biomarker: SGCA mRNA
Type: Predictive Biomarker (PRD)
Genes: SGCA; ADL; DAG2
Study 26298619 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 7503516 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7503516 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31703648 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 31703648 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25377269 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24088225 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study 24088225 — Biomarker: RAS pathway
Type: Safety Biomarker (SAF)
Study 20196388 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8088068 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8088068 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16029627 — Biomarker: GAPDH mRNA
Type: Predictive Biomarker (PRD)
Genes: GAPDH; GAPD; CDABP0047; OK/SW-cl.12
Study 10452405 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27593381 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 12585146 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30264918 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 21042763 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 14740952 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 11167770 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21329027 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 241598 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26089332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24725967 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 11705788 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 9626922 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 7829693 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 3050188 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 27243353 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 24111258 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17535867 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 10195532 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2405108 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31776782 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31566579 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31566579 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 23331559 — Biomarker: LTB mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB; TNFC; TNFSF3
Study 22353410 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 16400056 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15380045 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 15380045 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23523222 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 19920426 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 19920426 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16512478 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 16512478 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 10943872 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 10943872 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 10943872 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 10943872 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10943872 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 10943872 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 9301427 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3275752 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29401246 — Biomarker: WAP four-disulfide core domain protein 2
Type: Predictive Biomarker (PRD)
Genes: WFDC2; HE4; WAP5
Study 26738271 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 26738271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)