AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 30918967 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26087472 — Biomarker: SPARC mRNA
Type: Predictive Biomarker (PRD)
Genes: SPARC; ON
Study 24740208 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21149672 — Biomarker: ERCC8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC8; CKN1; CSA
Study 21149672 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 6122752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28699032 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 21044933 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12894958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8507812 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31218477 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 20856123 — Biomarker: MT2A mRNA
Type: Predictive Biomarker (PRD)
Genes: MT2A; CES1; MT2
Study 30025397 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 30025397 — Biomarker: CD24 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD24; CD24A
Study 30025397 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 30025397 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 27720506 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25082565 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 15586364 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 29573665 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29573665 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 24639042 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19383060 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 15159491 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 9828914 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31901246 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31901246 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23382484 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 23382484 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11006178 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31630870 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 31630870 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30378591 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 24430407 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16105425 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10597336 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17968979 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 28026901 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23433446 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 22340792 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 22340792 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 16757701 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 11255519 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31346621 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21692613 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 1877599 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23652897 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 23093401 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 23093401 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20145447 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18634163 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 12816624 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26371518 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26371518 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26371518 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21443446 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 21443446 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11495672 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9754980 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 30793466 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30793466 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30793466 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20378005 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 20378005 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 23168014 — Biomarker: EDNRA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDNRA; ETA; ETRA
Study 23168014 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 23168014 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 23168014 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 23168014 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17217741 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17217741 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1513113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31444162 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 28125093 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 24591332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16800833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3889027 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3889027 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 22417870 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22417870 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 14551174 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14551174 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10958766 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 8793612 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8793612 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27189028 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23742222 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23742222 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20211036 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 10522983 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 23175270 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 16552403 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 16552403 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16552403 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 14636839 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3917315 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 25237670 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 23348814 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 20492047 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9625541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30968604 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 25387260 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 7962336 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 7962336 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 10365642 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 1645768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28853202 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 28853202 — Biomarker: HSPA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA5; GRP78
Study 28853202 — Biomarker: BAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAK1; BAK; BCL2L7; CDN1
Study 28853202 — Biomarker: BAX mRNA
Type: Predictive Biomarker (PRD)
Genes: BAX; BCL2L4
Study 28853202 — Biomarker: miR-34a
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR34A
Study 19841330 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 11894174 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 646248 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11294130 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24555913 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 24555913 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22241059 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22241059 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 9656196 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 24560287 — Biomarker: AIFM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AIFM1; AIF; PDCD8
Study 19349586 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 17189867 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19125899 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19125899 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19125899 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29505517 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16373244 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16373244 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1978612 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 64653 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 23719582 — Biomarker: Carbonic anhydrase IX
Type: Predictive Biomarker (PRD)
Genes: CA9; G250; MN
Study 19273696 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 23193016 — Biomarker: DLX5 mRNA
Type: Predictive Biomarker (PRD)
Genes: DLX5
Study 23193016 — Biomarker: IGF2-AS
Type: Predictive Biomarker (PRD)
Study 23193016 — Biomarker: TP73 mRNA
Type: Predictive Biomarker (PRD)
Genes: TP73; P73
Study 22352262 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26363312 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 21915572 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14687899 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31141104 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 27126239 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 16135173 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 30971277 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8177478 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 8177478 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 30677319 — Biomarker: AFM mRNA
Type: Predictive Biomarker (PRD)
Genes: AFM; ALB2; ALBA
Study 2856769 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29251010 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 29251010 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26351087 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23910392 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 16412037 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24072699 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16809937 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 9208533 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9208533 — Biomarker: STIL mRNA
Type: Predictive Biomarker (PRD)
Genes: STIL; SIL
Study 19995098 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19995098 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27723261 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 23504220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8041534 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2537333 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2537333 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 1125586 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30641096 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30641096 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23062021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18653546 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 18653546 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29957279 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15780536 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 10521549 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21845038 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 21845038 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7649593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19852293 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 15730812 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 15730812 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9928566 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 7851270 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16554313 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 16114784 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16114784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10517426 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 25043337 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 15010183 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7835358 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16818033 — Biomarker: Gamma-Histone H2AX
Type: Pharmacodynamic Biomarker (PDY)
Genes: H2AX; H2AFX
Study 26903486 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15757851 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15757851 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15757851 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15757851 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24720928 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 12694346 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1992306 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 6362210 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 17323183 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1631861 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 6708394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31382822 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31382822 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15232503 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 15232503 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29044968 — Biomarker: DUT mRNA
Type: Predictive Biomarker (PRD)
Genes: DUT
Study 24520784 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 24520784 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24520784 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24520784 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18029492 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 30264170 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30264170 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 22288893 — Biomarker: Fatty acid amide hydrolase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: FAAH; FAAH1
Study 22288893 — Biomarker: CNR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNR1; CNR
Study 17394959 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8795770 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9736552 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7802178 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10681809 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7244391 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 26274346 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 22546623 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28035541 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10329884 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 1725198 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25304723 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 25304723 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25304723 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 10210023 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 24253534 — Biomarker: DPP10 mRNA
Type: Predictive Biomarker (PRD)
Genes: DPP10; DPRP3; KIAA1492
Study 24253534 — Biomarker: NPSR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NPSR1; GPR154; GPRA; PGR14
Study 24253534 — Biomarker: ADAM33 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM33; C20orf153; UNQ873/PRO1891
Study 23006968 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 12585141 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27270348 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 21624418 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 9603657 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 3415798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29242294 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 23021013 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 23021013 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 8635429 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study 16270403 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 76223 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 25792206 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 8467568 — Biomarker: ATP-binding cassette sub-family C member 11
Type: Predictive Biomarker (PRD)
Genes: ABCC11; MRP8
Study 8467568 — Biomarker: Calgranulin B
Type: Predictive Biomarker (PRD)
Genes: S100A9; CAGB; CFAG; MRP14
Study 8467568 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68