AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24084500 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 20738227 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 18219298 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12908569 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3902911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29228369 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28940820 — Biomarker: MYRF mRNA
Type: Predictive Biomarker (PRD)
Genes: MYRF; C11orf9; KIAA0954; MRF
Study 23135529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22992449 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7579506 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23800503 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9579769 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 9579769 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9579769 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7666079 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 29066877 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31879812 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31879812 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31879812 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18557720 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 18557720 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3521619 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 3521619 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22932944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17646564 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12526280 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15585144 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25028375 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20819415 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study 15882537 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27899759 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8138828 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8138828 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 27264120 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 12441222 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12441222 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27811309 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17950796 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12110818 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 6165255 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28947390 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24606094 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10408592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31905410 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19499845 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1385586 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 30808670 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 29278896 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 29278896 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 29278896 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25186922 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19618659 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19618659 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11642085 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2723121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2723121 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 27696393 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 22963131 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17540215 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 15384808 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7285499 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 28857336 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22976263 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22976263 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 22976263 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 9261032 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16705719 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11501728 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18583261 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18583261 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10217372 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 10217372 — Biomarker: PLTP mRNA
Type: Predictive Biomarker (PRD)
Genes: PLTP
Study 19969423 — Biomarker: DHDDS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHDDS; HDS
Study 17590368 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15452586 — Biomarker: HSPA8 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA8; HSC70; HSP73; HSPA10
Study 27860460 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 17475960 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 26812050 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26812050 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18422391 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12519437 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12519437 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 18419349 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 31163519 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 28893134 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 27808277 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 27808277 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 21483000 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 21483000 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 31937026 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18599554 — Biomarker: CD93 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD93; C1QR1; MXRA4
Study 18599554 — Biomarker: CDKN2A mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2A; CDKN2; MTS1
Study 18599554 — Biomarker: CDKN2B mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2B; MTS2
Study 7021412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30190369 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30190369 — Biomarker: Carbonic anhydrase IX
Type: Predictive Biomarker (PRD)
Genes: CA9; G250; MN
Study 30190369 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30190369 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 27908967 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 17519152 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 15219640 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 15219640 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 15219640 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11579345 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30037818 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 30037818 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 30037818 — Biomarker: CYP17A1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CYP17A1; CYP17; S17AH
Study 28182502 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 24094463 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 18086050 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15537681 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15537681 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9632998 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28627793 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 28627793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16253026 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 16253026 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 16253026 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 29246219 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 29246219 — Biomarker: MMP13 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP13
Study 29246219 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 25937516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22097612 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 16537846 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 11203813 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 26955982 — Biomarker: CPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPZ
Study 12777360 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10857365 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11835027 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 11835027 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3034034 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3034034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24398888 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24398888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15919007 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1920782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8005815 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10953 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28395180 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18840027 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 12574793 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12574793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27520400 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27520400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27520400 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27520400 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22425507 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19024795 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28597302 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19350266 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16458092 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15303255 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9813876 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 31821741 — Biomarker: ACAD8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAD8; ARC42; IBD
Study 23061976 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 25411740 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 3082257 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 31520633 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 21296957 — Biomarker: ALOX5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALOX5; LOG5
Study 19467834 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 17088135 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 17088135 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 16368340 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16368340 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12600870 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 29659116 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 27572136 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 24699248 — Biomarker: GPR119 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPR119
Study 24699248 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 24699248 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 21337116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8904257 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9322826 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16834839 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 10693734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9490144 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 9490144 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 18682410 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15591298 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12616317 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 12616317 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28514624 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 28514624 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21542721 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 17205817 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10966540 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1713484 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 31725942 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 31050355 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 23389112 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17540191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11451215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15602503 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 5320590 — Biomarker: CPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPZ
Study 5320590 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30753377 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19034493 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 9240877 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24282608 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 14561238 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10971167 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21616737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15882280 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 11172138 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2455099 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 14680665 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24118885 — Biomarker: DGAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DGAT1; AGRP1; DGAT
Study 24118885 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 20409605 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 18331385 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12582393 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 10684406 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6404404 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28743343 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 25567758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19623782 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 22189199 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 22189199 — Biomarker: NR1H3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1H3; LXRA
Study 22189199 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19958238 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study 19958238 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19958238 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 17400672 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 17400672 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9471040 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 2375235 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 31298405 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 24981180 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24981180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7611822 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 7611822 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 31441893 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 27683185 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 27683185 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 27683185 — Biomarker: CYP27B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 15532847 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15532847 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 21076278 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16290928 — Biomarker: TAC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAC1; NKA; NKNA; TAC2
Study 16290928 — Biomarker: ARID3B mRNA
Type: Predictive Biomarker (PRD)
Genes: ARID3B; BDP; DRIL2
Study 19735754 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 19735754 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21880792 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1