AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 10423075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1796409 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 1796409 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 11122727 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29412521 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26483047 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 18683781 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 6510013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8637302 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 22245235 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20968113 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2169701 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20395129 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 18356684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12839658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31717505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11798370 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1912739 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 7094972 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 12915640 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 10555031 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 7044932 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16923452 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16923452 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16923452 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2565329 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31757033 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26069290 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 31256014 — Biomarker: ZMYM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZMYM2; FIM; RAMP; ZNF198
Study 22446171 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 22446171 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 16646004 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11381289 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30016335 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 30016335 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22522403 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 22522403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30318065 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20415638 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6367368 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 6367368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19778661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8141172 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8141172 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30160543 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16527863 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 16527863 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 16527863 — Biomarker: SPR mRNA
Type: Predictive Biomarker (PRD)
Genes: SPR
Study 10965516 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 26674992 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23524367 — Biomarker: DPT mRNA
Type: Predictive Biomarker (PRD)
Genes: DPT
Study 12642710 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28891251 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 22178274 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 11704586 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 11704586 — Biomarker: CCR3 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CCR3; CMKBR3
Study 11704586 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 12810925 — Biomarker: NOD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOD2; CARD15; IBD1
Study 7847434 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27458060 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14739797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3357722 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24753831 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 21769731 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 19329822 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19329822 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14704596 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3081148 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 3081148 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 9497790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19209184 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19209184 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9543170 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23456697 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19665275 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9271481 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31237187 — Biomarker: SMPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMPD1; ASM
Study 20145786 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16768551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15076173 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15076173 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11126502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9333514 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 9333514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9333514 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8475234 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28185407 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19651171 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 9854507 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24732290 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 21848172 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 14976881 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 14976881 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 14976881 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8633187 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 8633187 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2568838 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31378394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24647908 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 19944392 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11858491 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 24020372 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 15502050 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28987470 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 28987470 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 9440743 — Biomarker: LSS mRNA
Type: Predictive Biomarker (PRD)
Genes: LSS; OSC
Study 2914540 — Biomarker: SSB mRNA
Type: Predictive Biomarker (PRD)
Genes: SSB
Study 4736626 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 31776293 — Biomarker: DGAT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DGAT2; HMFN1045; UNQ738/PRO1433
Study 19927026 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 19927026 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7639505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7639505 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 736633 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 15023936 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 15023936 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11772257 — Biomarker: PDE4D mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE4D; DPDE3
Study 11772257 — Biomarker: PDE4A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE4A; DPDE2
Study 26489030 — Biomarker: KCNE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNE1
Study 16390351 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 11174009 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11174009 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8299431 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8299431 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27040132 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27040132 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27040132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20861207 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20861207 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11789208 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20152239 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1719708 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 1719708 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 25872972 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19462498 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17261454 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15161690 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 15161690 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15161690 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9872248 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31912780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19342206 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11593098 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24659472 — Biomarker: SLC25A21 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A21; ODC
Study 17701685 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14980748 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9524044 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9524044 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31785830 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25969453 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 22339103 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 22339103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8736278 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25877812 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 20671330 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 28564127 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 10686803 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6125181 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15326115 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 15326115 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 9690480 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 27403851 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 27403851 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 27403851 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 25060669 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 26734954 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26734954 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26734954 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26734954 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22848584 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16045013 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 16045013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27225338 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18616780 — Biomarker: GSS mRNA
Type: Predictive Biomarker (PRD)
Genes: GSS
Study 7519032 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 20644943 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20644943 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 15140780 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9821562 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 23368826 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 23368826 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 20579847 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 19279365 — Biomarker: P4HB mRNA
Type: Predictive Biomarker (PRD)
Genes: P4HB; ERBA2L; PDI; PDIA1; PO4DB
Study 11463988 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 22550196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15744147 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 27681572 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6357901 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17484872 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 31036580 — Biomarker: GNE mRNA
Type: Predictive Biomarker (PRD)
Genes: GNE; GLCNE
Study 22196270 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 15682684 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 15682684 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 29191585 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10671339 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 22901955 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20536619 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12145999 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 30677646 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 19196111 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 8352424 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 3112727 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 27192969 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 27192969 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 20570883 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20570883 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 12803737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15886669 — Biomarker: Platelet-derived growth factor B
Type: Pharmacodynamic Biomarker (PDY)
Genes: PDGFB; PDGF2; SIS
Study 12097537 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27183922 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27183922 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22855206 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22855206 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 19661927 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2282920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22083873 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12529549 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 12529549 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 12529549 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 12529549 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 10949811 — Biomarker: PHEX mRNA
Type: Predictive Biomarker (PRD)
Genes: PHEX; PEX
Study 4072599 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26575158 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 25063191 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 18360068 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12593493 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12593493 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10593132 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 30328108 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 28078862 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28078862 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28078862 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28078862 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28078862 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17413560 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29202488 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29202488 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 29202488 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 29202488 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29202488 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22027699 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 9188761 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 9188761 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 8442581 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27622723 — Biomarker: UGT2B15 mRNA
Type: Predictive Biomarker (PRD)
Genes: UGT2B15; UGT2B8
Study 18575626 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 16042882 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31077181 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21360715 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3