AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 29866645 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27501153 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 27501153 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 27501153 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 17483103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16841666 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 10493671 — Biomarker: DMA mRNA
Type: Predictive Biomarker (PRD)
Genes: DMA; HLA-DMA; hCG_2001572
Study 10493671 — Biomarker: HLA-DMB mRNA
Type: Predictive Biomarker (PRD)
Genes: HLA-DMB; DMB; RING7
Study 15973062 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 12595862 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 8701398 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 8701398 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25006719 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 25006719 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 25006719 — Biomarker: Th2 cell
Type: Safety Biomarker (SAF)
Study 15471837 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 9263614 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30644785 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30644785 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9835498 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21684281 — Biomarker: TPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH1; TPH; TPRH; TRPH
Study 28399902 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28399902 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28399902 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 10688394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15545047 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15545047 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15545047 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21968126 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21968126 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18721079 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 25893955 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21563505 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25041791 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19474141 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29850873 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24492839 — Biomarker: COX4I1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COX4I1; COX4
Study 24492839 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 24492839 — Biomarker: MAPK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK1; ERK2; PRKM1; PRKM2
Study 24492839 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 20533969 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12853535 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 27660650 — Biomarker: KY mRNA
Type: Predictive Biomarker (PRD)
Genes: KY
Study 17537770 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 17537770 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9443925 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31821071 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 31821071 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 30244144 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 26443829 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26686359 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25262636 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 22549092 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 20569714 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20569714 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12471316 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30439452 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25772806 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23527358 — Biomarker: CPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPB1; CPB; PCPB
Study 11463596 — Biomarker: SIGLEC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIGLEC1; SN
Study 30019653 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 20102855 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14872148 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25851895 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 25851895 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 25851895 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 12584036 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9086359 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30795753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30795753 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18325918 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 23548570 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18826865 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17396041 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15711571 — Biomarker: CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR1; C3BR
Study 31256870 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25138265 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 25138265 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 3534901 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 30895460 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30895460 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28696415 — Biomarker: STAC mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAC; STAC1
Study 28696415 — Biomarker: ZNF385D mRNA
Type: Predictive Biomarker (PRD)
Genes: ZNF385D; ZNF659
Study 28696415 — Biomarker: NCAM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NCAM1; NCAM
Study 28696415 — Biomarker: KMT2E mRNA
Type: Predictive Biomarker (PRD)
Genes: KMT2E; MLL5
Study 23212150 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 23212150 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 12656658 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 3946946 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 29878870 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 22797673 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21129229 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 21215382 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21215382 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18661524 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 12439651 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28229374 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 28229374 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 28229374 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 28229374 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 28229374 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 20024739 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17901665 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17901665 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 18800454 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18800454 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29380563 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 22108921 — Biomarker: Complement factor D
Type: Safety Biomarker (SAF)
Genes: CFD; DF; PFD
Study 2660750 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 27664274 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 24577383 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9825367 — Biomarker: RFC1
Type: Safety Biomarker (SAF)
Genes: A1; PO-GA; RFC140; MHCBFB
Study 2562233 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2562233 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 29538243 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 27513406 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23701571 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22868522 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20602006 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20602006 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12819247 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30175792 — Biomarker: XG mRNA
Type: Predictive Biomarker (PRD)
Genes: XG; PBDX
Study 25037750 — Biomarker: LHX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LHX2; LH2
Study 16048137 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8534781 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 8534781 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31580931 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30149898 — Biomarker: WAP four-disulfide core domain protein 2
Type: Predictive Biomarker (PRD)
Genes: WFDC2; HE4; WAP5
Study 30149898 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 26123137 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 26123137 — Biomarker: Dihydrothymine dehydrogenase
Type: Safety Biomarker (SAF)
Genes: DPYD
Study 24971988 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 26932132 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7877544 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30171497 — Biomarker: HRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: HRAS; HRAS1
Study 30171497 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 25486372 — Biomarker: CGAS mRNA
Type: Predictive Biomarker (PRD)
Genes: CGAS; C6orf150; MB21D1
Study 23759749 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23759749 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 23759749 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 16883907 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 16883907 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16883907 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22170364 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8950879 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8950879 — Biomarker: New morphometric vertebral fractures
Type: Surrogate Endpoint (SUR)
Study 6783861 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2476624 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26114854 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16702369 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 11742880 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11742880 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15342298 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15342298 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 22006202 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22006202 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18049022 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18049022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18049022 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11004845 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11004845 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 11004845 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 11004845 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 11004845 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 1618361 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15964386 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30506227 — Biomarker: NOVA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOVA2; ANOVA; NOVA3
Study 18324566 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18324566 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15944869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8872291 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8872291 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 8872291 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 8872291 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27030325 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 27030325 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 25351025 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22583627 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 19915976 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28846633 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26244985 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22891564 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 22891564 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 22891564 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30265563 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27927679 — Biomarker: ALPI mRNA
Type: Predictive Biomarker (PRD)
Genes: ALPI
Study 11114960 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11114960 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8264873 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 17897465 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9793844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2558817 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23257975 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23257975 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11704081 — Biomarker: LTB4R mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 9606848 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 29606517 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20802351 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19054833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10348802 — Biomarker: CYP2E1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2E1; CYP2E
Study 10348802 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 1777376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6519740 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6519740 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27566633 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20399240 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 31022932 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31022932 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22206712 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study 22206712 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 23532145 — Biomarker: MTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 8261880 — Biomarker: MAOB mRNA
Type: Predictive Biomarker (PRD)
Genes: MAOB
Study 24201230 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21613553 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19549290 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 19549290 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19549290 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11231700 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7912123 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9094875 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9094875 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22627991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10574621 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 2935737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29893769 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 29893769 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 29893769 — Biomarker: CCND1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND1; BCL1; PRAD1
Study 29893769 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 29893769 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 29893769 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29893769 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29893769 — Biomarker: CCNE2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCNE2
Study 29893769 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 9892860 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 24859203 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21390056 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30939905 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 10898125 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10898125 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9360001 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9360001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2879292 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29856470 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 10382902 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29126178 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29126178 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)