AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 22556172 — Biomarker: 14-3-3 protein sigma
Type: Predictive Biomarker (PRD)
Genes: SFN; HME1
Study 20053692 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3075649 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17893629 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17893629 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 17893629 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 29225332 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29225332 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16865075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31626906 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 31626906 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27397921 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18756885 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 10722237 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30157532 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15331124 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15331124 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9442423 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 3232799 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23558598 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21108561 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21108561 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 8124904 — Biomarker: GCA mRNA
Type: Predictive Biomarker (PRD)
Genes: GCA; GCL
Study 21769850 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16879825 — Biomarker: WT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WT1
Study 27655755 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27655755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27655755 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 24548977 — Biomarker: PLTP mRNA
Type: Predictive Biomarker (PRD)
Genes: PLTP
Study 24548977 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15990174 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 17898405 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 31129617 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 22573127 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25986854 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21247480 — Biomarker: NOD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOD2; CARD15; IBD1
Study 26645254 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20369615 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20369615 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 26829251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17106274 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17106274 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2534412 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 25109699 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 21999662 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 16803911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22367794 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12480497 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12480497 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12480497 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 30238636 — Biomarker: TRPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPA1; ANKTM1
Study 21226818 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 1417632 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23573950 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 11224624 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16936704 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 15238771 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9408700 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18565884 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 16043985 — Biomarker: IRAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRAK1; IRAK
Study 16043985 — Biomarker: TRAF6 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRAF6; RNF85
Study 16043985 — Biomarker: DPEP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DPEP1; MDP; RDP
Study 7718459 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 7718459 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study 7718459 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 2381302 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30911274 — Biomarker: TNFRSF10B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9; UNQ160/PRO186
Study 27451030 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 12089223 — Biomarker: ABCG2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 30707970 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 22354743 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18030230 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16219012 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 25379688 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22546837 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 22546837 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 19046909 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15138163 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30590827 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 20884178 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 9493577 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 27935240 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25452012 — Biomarker: LSS mRNA
Type: Predictive Biomarker (PRD)
Genes: LSS; OSC
Study 24326421 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 24326421 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15763716 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25627076 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 25627076 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12873621 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10416877 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31149869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31149869 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22156352 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7495240 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 388395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 388395 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 388395 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 388395 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29352654 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29628560 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25385729 — Biomarker: BCL6 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 25385729 — Biomarker: IRF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRF4; MUM1
Study 25385729 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 25385729 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 16238909 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16238909 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31556454 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22878802 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 17532398 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 11552002 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19422337 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 16934051 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 16934051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1363221 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 1363221 — Biomarker: Coagulation factor Va
Type: Safety Biomarker (SAF)
Genes: F5
Study 1363221 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30804464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23357150 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19874992 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19874992 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28177671 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 28177671 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 3304386 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31566845 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 18376691 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18376691 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11004031 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11004031 — Biomarker: Interleukin 1 alpha
Type: Safety Biomarker (SAF)
Genes: IL1A; IL1F1
Study 11004031 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 11004031 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8400072 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24382064 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15781736 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8663853 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8663853 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8663853 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 6479183 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19765954 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15782288 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31740368 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31740368 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26040499 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study 26040499 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26040499 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 26040499 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22142711 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 11413894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26485913 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3401524 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 31077827 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31077827 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31077827 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18993165 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18993165 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17473825 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 9665110 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9665110 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 29166829 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 28131786 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 3416848 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25913848 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 29020995 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26093812 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8160789 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 8160789 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 28987930 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 28583653 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26304935 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 1313549 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20647096 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 16028466 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2161058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7392541 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7392541 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18570561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16092057 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6840159 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31292965 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25746039 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 19364966 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20525211 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20525211 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15148337 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 11389423 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9247759 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3954127 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11445756 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11445756 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11445756 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 29458447 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26804607 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 26755382 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26755382 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25266967 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 16392436 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1284345 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 24972708 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17650661 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 12234851 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 30729456 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27021357 — Biomarker: GNS mRNA
Type: Predictive Biomarker (PRD)
Genes: GNS
Study 25566618 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 22233522 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 16245354 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28889792 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 18167644 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 24499830 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24499830 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12904518 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24578471 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29383408 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 29383408 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18425398 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16607097 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9665269 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 3278434 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25769330 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25769330 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25769330 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12797397 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24525553 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 25588 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 26940151 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 17293706 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17293706 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28832441 — Biomarker: MVK mRNA
Type: Predictive Biomarker (PRD)
Genes: MVK
Study 23714653 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18451231 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 12153962 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 6767404 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6767404 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 24926949 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23441533 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20212395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)