AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31468673 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 31468673 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 31468673 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31468673 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31468673 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 20621377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18416220 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 9639442 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 18349403 — Biomarker: MYCN mRNA
Type: Predictive Biomarker (PRD)
Genes: MYCN; BHLHE37; NMYC
Study 10762214 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8272478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3802705 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20413522 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7757354 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 30681939 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27951450 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 26154930 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 26154930 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26154930 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26154930 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 26154930 — Biomarker: Angiopoietin-1
Type: Monitoring Biomarker (MOI)
Genes: ANGPT1; KIAA0003
Study 22166738 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15224273 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 11423921 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 11423921 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9243749 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 9243749 — Biomarker: HLA-DQB1
Type: Safety Biomarker (SAF)
Genes: IDDM1; CELIAC1
Study 7961239 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3591419 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3591419 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20444849 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19040592 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19040592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2591463 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2591463 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21903021 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12754885 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8815481 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21523325 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 18204476 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 16055956 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10469339 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10469339 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 10469339 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 10469339 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 2186579 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 37747 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 37747 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21551506 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17164314 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 30398646 — Biomarker: GLO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLO1
Study 20447925 — Biomarker: MCM6 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCM6
Study 7124311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28743816 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28743816 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 26729441 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 14750091 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14750091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16585662 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25891453 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25891453 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25891453 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20938444 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 8922355 — Biomarker: HLA-DQB1
Type: Safety Biomarker (SAF)
Genes: IDDM1; CELIAC1
Study 30887760 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 14712431 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 7986302 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 7986302 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28371685 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28371685 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23635604 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 23635604 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 10768435 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 11548874 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 11548874 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11548874 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11548874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30929250 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 30929250 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21797975 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 16772388 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 11523071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8380631 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 28128223 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 26200619 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26200619 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1533941 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 2908814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27271183 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11383326 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 11383326 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8067227 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23298135 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23298135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27780504 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20826964 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 14619332 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28139626 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 12798823 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6178592 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 6178592 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 19922896 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10423601 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10423601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7943382 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28215316 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28215316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23811808 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10872898 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26932345 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26932345 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26932345 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18272891 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 16204792 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 8390084 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31674093 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 10619534 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 616209 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16303780 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16303780 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15504192 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2467137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28148474 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23680036 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23680036 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23680036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16271817 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 6337405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30286797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24648302 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24648302 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24648302 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 19660897 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15538130 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 15538130 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 26585287 — Biomarker: PNOC mRNA
Type: Predictive Biomarker (PRD)
Genes: PNOC; OFQ
Study 26585287 — Biomarker: NOL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOL3; ARC; NOP
Study 23767831 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23767831 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23767831 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study 24708917 — Biomarker: SELENOP mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENOP; SELP; SEPP1
Study 24708917 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20555331 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20555331 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 8910175 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 8910175 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8910175 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6359947 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29666026 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29666026 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29666026 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 29666026 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28972045 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 28972045 — Biomarker: ERCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC2; XPD; XPDC
Study 28972045 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 28972045 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 17690191 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31429629 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20942668 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 18219181 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16845627 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 16845627 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 7989949 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7989949 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24799100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16368883 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 11739159 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 26813432 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26813432 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 26813432 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 23797426 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 16328487 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9131955 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8383769 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8383769 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 28470118 — Biomarker: miR-124
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28470118 — Biomarker: miR-375-3p
Type: Safety Biomarker (SAF)
Genes: MIR375
Study 28470118 — Biomarker: miR-375
Type: Safety Biomarker (SAF)
Genes: MIR375
Study 28470118 — Biomarker: miR-150
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR150
Study 28470118 — Biomarker: miR-31
Type: Predictive Biomarker (PRD)
Genes: MIR31
Study 11531679 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8315260 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8315260 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 2894218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23746559 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 30842392 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27739325 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 27739325 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 23490598 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23490598 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 11967790 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3914572 — Biomarker: ERCC8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC8; CKN1; CSA
Study 30940692 — Biomarker: Phosphatidylinositol-trisphosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 30144891 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30144891 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 7857734 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 7857734 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7857734 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24744152 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22113951 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19134277 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1720217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1720217 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 29754649 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29754649 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17911647 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12364969 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2142577 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2142577 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25636048 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25636048 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21280197 — Biomarker: MTX3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MTX3
Study 16776933 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9754589 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7836943 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21302486 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26464454 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 21472530 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21472530 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21472530 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 16551312 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9640082 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29542334 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 29542334 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26534969 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23109251 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16458213 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14613739 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30570839 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 21727201 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 21727201 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 17179200 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9678311 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 9678311 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 30504715 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 21158963 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 9534293 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30676838 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 27157293 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30