AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT01075373 — Biomarker: DISC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DISC1; KIAA0457
Study NCT01075373 — Biomarker: NRG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study NCT01075373 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study NCT01075373 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study NCT01075373 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study NCT01075373 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02758444 — Biomarker: EED mRNA
Type: Predictive Biomarker (PRD)
Genes: EED
Study NCT01048034 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01733680 — Biomarker: SLC9A9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC9A9; NHE9; Nbla00118
Study NCT01315262 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study NCT01315262 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01391533 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT02100696 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03400722 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT01651403 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT00339196 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00080899 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study NCT01260532 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study NCT01260532 — Biomarker: CTLA4
Type: Predictive Biomarker (PRD)
Genes: CD152; CD; GSE; CTLA-4
Study NCT01260532 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study NCT01260532 — Biomarker: ICOS mRNA
Type: Predictive Biomarker (PRD)
Genes: ICOS; AILIM
Study NCT01260532 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00173849 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study NCT01818674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00684515 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04145232 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04145232 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00492128 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03789058 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00720460 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00743938 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02417584 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03285425 — Biomarker: CLN6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLN6
Study NCT00006033 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT00530439 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01570569 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study NCT01570569 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study NCT01570569 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT01570569 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study NCT01658449 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT00859703 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT04507984 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study NCT04236258 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02272686 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study NCT01396070 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study NCT01960894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00504959 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT00983047 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00983047 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03370497 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT03370497 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study NCT02095743 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02053376 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02053376 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01742286 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT02400385 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study NCT00000921 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00751868 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00217178 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT00441857 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study NCT03233854 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT03233854 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study NCT00017862 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study NCT00017862 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT01490489 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT03706287 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03706287 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT03706287 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT03706287 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04059588 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study NCT03329937 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03329937 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00003280 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT04170595 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04170595 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02258360 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00709007 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04106362 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT03718143 — Biomarker: WEE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WEE1
Study NCT00132470 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01512511 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00990704 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study NCT01465126 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT00004661 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study NCT02476539 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02476539 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03056508 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03056508 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03056508 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT03056508 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03204734 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03204734 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT03204734 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT04753398 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00360659 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00005601 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT01082315 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01082315 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT04082819 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02656693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05446818 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01197170 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT01534364 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT01285908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02163473 — Biomarker: Hypoxia-inducible factor 1-alpha
Type: Predictive Biomarker (PRD)
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study NCT01184482 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01184482 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00000511 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01905358 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT00437645 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03951818 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01791712 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01791712 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT02225002 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study NCT02225002 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01180582 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02955030 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT01065974 — Biomarker: HFE mRNA
Type: Predictive Biomarker (PRD)
Genes: HFE; HLAH
Study NCT03320577 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00818701 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study NCT01131195 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02437162 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00737815 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03013296 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT00120419 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT03693157 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02574637 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03380299 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study NCT04311086 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04374942 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT01420146 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00430508 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00509483 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT00485368 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT02074410 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study NCT04504552 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01441570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04335136 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT03122834 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT01489696 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01655004 — Biomarker: UGT2B17 mRNA
Type: Predictive Biomarker (PRD)
Genes: UGT2B17
Study NCT03144466 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03675880 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT04208178 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04208178 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study NCT02906176 — Biomarker: SLCO2B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study NCT02906176 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT00311467 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT04958356 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study NCT01383889 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02238080 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02238080 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT03777683 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01276236 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study NCT01110200 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00011453 — Biomarker: Nqo1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: NQO1; DIA4; NMOR1
Study NCT02322450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00325624 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00810017 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01288092 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01288092 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study NCT01288092 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT01288092 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT03369145 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study NCT03369145 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study NCT05178875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03146533 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT01209702 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01209702 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT00508404 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT01500356 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01500356 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02315365 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04708314 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study NCT03291366 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT05066490 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT00295373 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study NCT00295373 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03542786 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04608695 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT04608695 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study NCT02841371 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT02841371 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study NCT02780882 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT02780882 — Biomarker: Urine free cortisol
Type: Surrogate Endpoint (SUR)
Study NCT03891901 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT03674827 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT04536883 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study NCT02913456 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03400800 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study NCT03400800 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02543255 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study NCT01425112 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01425112 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT03491410 — Biomarker: PI3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PI3; WAP3; WFDC14
Study NCT01776216 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00776516 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT03572556 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT03572556 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study NCT02677155 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00931489 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study NCT02858076 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02858076 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT01063283 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00862082 — Biomarker: AKR1C3 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKR1C3; DDH1; HSD17B5; KIAA0119; PGFS
Study NCT01866267 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study NCT01050400 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study NCT00083720 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00083720 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT04536870 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study NCT03382574 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT04083768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01521793 — Biomarker: RPE65 mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE65
Study NCT01521793 — Biomarker: LRAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LRAT
Study NCT02897479 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT01518764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01420211 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study NCT01420211 — Biomarker: SLCO1B3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study NCT02727335 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT01265524 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study NCT02667080 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study NCT02093819 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study NCT00500682 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)