AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 21878067 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12525260 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 30583542 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23327881 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 23327881 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16189764 — Biomarker: HGD mRNA
Type: Predictive Biomarker (PRD)
Genes: HGD; HGO
Study 11823664 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study 23843881 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 18952082 — Biomarker: MTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 11213534 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3969876 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26773737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12383815 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 794022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28235493 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 17894896 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3291529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22563215 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 19017764 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 25407798 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25407798 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16159809 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16159809 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31159750 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 31159750 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 26012783 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9390335 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 9390335 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 12522893 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30340505 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30340505 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30340505 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 18417963 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18417963 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12431854 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 30167807 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15579724 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 7607199 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18547287 — Biomarker: MUC5AC mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MUC5AC; MUC5
Study 18547287 — Biomarker: MUC5B mRNA
Type: Predictive Biomarker (PRD)
Genes: MUC5B; MUC5
Study 18547287 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 18547287 — Biomarker: MUC4 mRNA
Type: Predictive Biomarker (PRD)
Genes: MUC4
Study 22170807 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 19875277 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10232443 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 27631091 — Biomarker: New morphometric vertebral fractures
Type: Surrogate Endpoint (SUR)
Study 27631091 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26458336 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 25675721 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25303096 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 8308716 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29746376 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16309684 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 12775735 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 29767743 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 29767743 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 29767743 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31565781 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22745272 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 24016248 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24016248 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18596116 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 15764730 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 15764730 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15764730 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 22136711 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24675910 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 22089177 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 16645532 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 6762167 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29370424 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29370424 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25559494 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 25559494 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 25559494 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 25559494 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16601362 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 10754612 — Biomarker: PPIA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPIA; CYPA
Study 3908125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3908125 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 3908125 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 15957830 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7552524 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 7552524 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25381629 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25381629 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 25381629 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10883412 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10883412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24720919 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24720919 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11641310 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9588696 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31113932 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 31113932 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 25433580 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 25433580 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25433580 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25433580 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25433580 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 25433580 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 25015740 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 10880799 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10880799 — Biomarker: KCNH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNH2; ERG; ERG1; HERG
Study 6106148 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24613434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24613434 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24613434 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22804104 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8948610 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 7768073 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 2382605 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31898874 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19779491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30792342 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 29086478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29086478 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 25637602 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 25637602 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25637602 — Biomarker: MYH6 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYH6; MYHCA
Study 25637602 — Biomarker: ATP2A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATP2A2; ATP2B
Study 25637602 — Biomarker: PLN mRNA
Type: Predictive Biomarker (PRD)
Genes: PLN; PLB
Study 25637602 — Biomarker: RYR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RYR2
Study 25637602 — Biomarker: ADRA1D mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRA1D; ADRA1A
Study 25637602 — Biomarker: ADRB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB1; ADRB1R; B1AR
Study 25637602 — Biomarker: MYL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYL3
Study 25637602 — Biomarker: PDHX mRNA
Type: Predictive Biomarker (PRD)
Genes: PDHX; PDX1
Study 25637602 — Biomarker: CPT1B mRNA
Type: Predictive Biomarker (PRD)
Genes: CPT1B; KIAA1670
Study 16962720 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25053587 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 9086127 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 29361981 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 22969845 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17713431 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15075539 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11838566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9483586 — Biomarker: Th2 cell
Type: Safety Biomarker (SAF)
Study 23886280 — Biomarker: PITRM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PITRM1; KIAA1104; MP1; PREP
Study 12716689 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1574976 — Biomarker: PCLAF mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 29576369 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25077916 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 25077916 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 19535219 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 12909505 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6349668 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17397305 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 15086925 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15086925 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15086925 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15086925 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19189 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 31911130 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26406293 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 21540233 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 23296097 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 8489354 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 28007133 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 25876338 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21557265 — Biomarker: DMA mRNA
Type: Predictive Biomarker (PRD)
Genes: DMA; HLA-DMA; hCG_2001572
Study 20536517 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 19856616 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3293872 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28220486 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 25332252 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 25332252 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 21478777 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18855558 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 30239830 — Biomarker: FUT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FUT2; SEC2
Study 11149624 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20822968 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 20822968 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 20822968 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15848713 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 28618724 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12877903 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12877903 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 12877903 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25968470 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17003295 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17003295 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15302082 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18299694 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9366102 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9366102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 416322 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2147909 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28183547 — Biomarker: PSG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSG1; B1G1; PSBG1; PSGGA
Study 28183547 — Biomarker: PSG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSG2; PSBG2
Study 28183547 — Biomarker: PSG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSG3
Study 2845349 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 31675124 — Biomarker: SOCS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOCS1; SSI1; TIP3
Study 31675124 — Biomarker: INPP5D mRNA
Type: Predictive Biomarker (PRD)
Genes: INPP5D; SHIP; SHIP1
Study 31675124 — Biomarker: miR-155
Type: Safety Biomarker (SAF)
Genes: MIR155
Study 6467800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27052122 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 22415232 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 25521275 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 19885944 — Biomarker: PCSK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK5; PC5; PC6
Study 19885944 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 8923850 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 3888229 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3888229 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16317014 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 14528069 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31170926 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19488607 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19488607 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15832031 — Biomarker: SLBP mRNA
Type: Predictive Biomarker (PRD)
Genes: SLBP; HBP
Study 6351148 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25918755 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1500686 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 30536163 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 9054246 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15545877 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9450166 — Biomarker: ARID3B mRNA
Type: Predictive Biomarker (PRD)
Genes: ARID3B; BDP; DRIL2
Study 9450166 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29322434 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 23141812 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 23141812 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 2140489 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2140489 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 17023769 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22535754 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22535754 — Biomarker: TNFRSF1A
Type: Predictive Biomarker (PRD)
Genes: TNF-R; TNFAR; TNFR60; TNF-R-I; CD120a; TNF-R55
Study 22535754 — Biomarker: TNFR1B
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 22535754 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 14745756 — Biomarker: CNR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNR1; CNR
Study 11756577 — Biomarker: GAD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD2; GAD65
Study 27317093 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 10952840 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 10952840 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9062836 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27450552 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 27450552 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27450552 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10674617 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10674617 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6382172 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19121921 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19121921 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 28566194 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28566194 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26202097 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11918129 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2