AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 26374825 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12929752 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12929752 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 30445008 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21160226 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 15587094 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11522968 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 23759267 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24118860 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15802769 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6123837 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 840125 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 29440016 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24447343 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 24447343 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24447343 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 24447343 — Biomarker: Platelet to lymphocyte
Type: Safety Biomarker (SAF)
Study 24447343 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17576071 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 11952432 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9615498 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2649022 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23296464 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 7930473 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 25505230 — Biomarker: POLE mRNA
Type: Predictive Biomarker (PRD)
Genes: POLE; POLE1
Study 24713545 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 20151839 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 15896918 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 3932499 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 29543938 — Biomarker: ADAM17 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM17; CSVP; TACE
Study 12389268 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29898171 — Biomarker: LSS mRNA
Type: Predictive Biomarker (PRD)
Genes: LSS; OSC
Study 22332827 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 20688574 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15642074 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7755658 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 7755658 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 7755658 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31162140 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25606478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23835693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28246005 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 20553856 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 10812530 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 16181237 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10073874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31034640 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26930244 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22702540 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15070956 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30905725 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 26001837 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 9403805 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 12727577 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31564118 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11174383 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11174383 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11174383 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 28642082 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28642082 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18258620 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 18258620 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 14562857 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6097377 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30665383 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 27127325 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27127325 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 25444588 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 21956486 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17313701 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 31837640 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31837640 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 30232789 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23781882 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 23781882 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 8785393 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6666222 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30231074 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28110894 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28110894 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 9070551 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12959317 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 3772833 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 31758920 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 31758920 — Biomarker: SULT1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SULT1A1; STP; STP1; OK/SW-cl.88
Study 23770788 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23770788 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 23770788 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 18485028 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 14553956 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11061364 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2439798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31306389 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31306389 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31306389 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31306389 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24313546 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24313546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24313546 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12022620 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 24916555 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 18415809 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 25790673 — Biomarker: DOCK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DOCK3; KIAA0299; MOCA
Study 23521816 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23521816 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15063428 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20503397 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12645716 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10389911 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10389911 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31594635 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 26754625 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 26754625 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 17536453 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 9542322 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 9542322 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24266960 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24266960 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17194902 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 8143399 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28526381 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23731242 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19885781 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 19885781 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 16456024 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16456024 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 16456024 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 23764734 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 17641003 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12532161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17434899 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12927020 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12927020 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 9174500 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20807460 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18537939 — Biomarker: OPRD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OPRD1; OPRD
Study 18537939 — Biomarker: OPRK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OPRK1; OPRK
Study 17010738 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7047173 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27454528 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 18710605 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17617307 — Biomarker: DDT mRNA
Type: Predictive Biomarker (PRD)
Genes: DDT
Study 17617307 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 14983420 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 11607801 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9699761 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26273138 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23732551 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 19643572 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 7798822 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29621201 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 29621201 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 29621201 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 29621201 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 29621201 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 29621201 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 18029476 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18029476 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18029476 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 7607280 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 26160210 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 26160210 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22997212 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16554455 — Biomarker: Urine free cortisol
Type: Surrogate Endpoint (SUR)
Study 12713767 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3969861 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20973735 — Biomarker: Serum hemoglobin A1C
Type: Surrogate Endpoint (SUR)
Study 20973735 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20973735 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11145325 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 21164548 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21164548 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21164548 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3896555 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22215656 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22215656 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22215656 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 28158151 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 18467721 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 27973684 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 27973684 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26359007 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23829159 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 19074546 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 8190572 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 30051222 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 22853847 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20929124 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18761785 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17906162 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 17906162 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30585458 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 17628686 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26549704 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 15159685 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9792567 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 834152 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31354089 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 17516972 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26302093 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21318601 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 17389292 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17389292 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15009002 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 3102991 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 26511012 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 24374901 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24374901 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24374901 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 22745145 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 22745145 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22745145 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 17427172 — Biomarker: ADAM17 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM17; CSVP; TACE
Study 15583702 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 7843752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7843752 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2192572 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30792343 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 17542407 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14718904 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 8516521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26158245 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19827055 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20184589 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25425220 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 17608679 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 8168806 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 3285215 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19401349 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 14751655 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30843141 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29176462 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 23313603 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 22137068 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19005996 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19005996 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31832789 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7965483 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 30355202 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 24645944 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)