AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 15669554 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23713299 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23713299 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23713299 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 16600816 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 16600816 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 16600816 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 16600816 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 10867111 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 10867111 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 9263770 — Biomarker: PGM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PGM1
Study 30368939 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12404273 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9633494 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15381116 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 15381116 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8506191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22617279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28062595 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 23896980 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23896980 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23896980 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22321594 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18927241 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 11206684 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11206684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28392436 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28392436 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28392436 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 21109557 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11300383 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 1725023 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1725023 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29575637 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29575637 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 29575637 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23652351 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 23652351 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 2685177 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24039738 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9330023 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 24453831 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 13678872 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10202683 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 540459 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31851556 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 31851556 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 17101560 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 17101560 — Biomarker: DBI mRNA
Type: Predictive Biomarker (PRD)
Genes: DBI
Study 23607773 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 20521988 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16182833 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1505563 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16421366 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1505293 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 30809971 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18288274 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 18288274 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18288274 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 378509 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 30010923 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 25642918 — Biomarker: TPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH1; TPH; TPRH; TRPH
Study 25642918 — Biomarker: SLC6A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 25642918 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 25642918 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 25642918 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 7541916 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7541916 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30223023 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 28341759 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 28341759 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 28341759 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26667367 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 23745525 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 22768976 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22768976 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 14712427 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14712427 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29368152 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29368152 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 22377563 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 16555577 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16555577 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10528960 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 6168837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31088856 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 8199724 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31971474 — Biomarker: CRYAB mRNA
Type: Predictive Biomarker (PRD)
Genes: CRYAB; CRYA2; HSPB5
Study 31971474 — Biomarker: HSPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPB1; HSP27; HSP28
Study 26251666 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 26251666 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7849541 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21884028 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12663271 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 10052405 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 31665115 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15006256 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1421710 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 24586292 — Biomarker: COTL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COTL1; CLP
Study 7076881 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24990880 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20222106 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16959304 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 9745993 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9745993 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11962062 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 26908625 — Biomarker: SLC39A8 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC39A8; BIGM103; ZIP8; PP3105
Study 26908625 — Biomarker: POC1B mRNA
Type: Predictive Biomarker (PRD)
Genes: POC1B; WDR51B
Study 26908625 — Biomarker: GALNT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GALNT4
Study 26908625 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 22914601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17148569 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 17148569 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 16311459 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2186854 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 2186854 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22678100 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 20966605 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18387222 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 11841418 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 28177133 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28177133 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12751274 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16613263 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 16613263 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 1827010 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24385387 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19056706 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15026402 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 3056505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20846961 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16879679 — Biomarker: SPARC mRNA
Type: Predictive Biomarker (PRD)
Genes: SPARC; ON
Study 12911659 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 9108457 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20808854 — Biomarker: Survival motor neuron protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 20808854 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 10449882 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 24120550 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19808134 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 30453599 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8600545 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2010560 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26309133 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26309133 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23208319 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 23208319 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23208319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16972973 — Biomarker: TTN mRNA
Type: Predictive Biomarker (PRD)
Genes: TTN
Study 15610084 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 30858012 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23930160 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30862667 — Biomarker: TRPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPA1; ANKTM1
Study 23698063 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21372309 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 11142481 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 26527417 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 19094432 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19094432 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 15663590 — Biomarker: NFIC mRNA
Type: Predictive Biomarker (PRD)
Genes: NFIC; NFI
Study 2350208 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 31478799 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23866850 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 23866850 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 19120333 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 19120333 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16829185 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 11096237 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 31733985 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20632084 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26273264 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 31183514 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26493267 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 26493267 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 19491536 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14763917 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 11248662 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27194175 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20377585 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12503692 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12503692 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 12503692 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 335867 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3890279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12843799 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 12843799 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11007235 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 6494011 — Biomarker: RTN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RTN1; NSP
Study 26250966 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26250966 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 23915885 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10883872 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 29925930 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 29925930 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19183127 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 19183127 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9215520 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28139405 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 16263817 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 16263817 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 31710134 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24059116 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 21868346 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 7486185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28471950 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 23398944 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21290392 — Biomarker: NES mRNA
Type: Predictive Biomarker (PRD)
Genes: NES; Nbla00170
Study 19118130 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 17185355 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 16761192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8408940 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19020919 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3363288 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 30351172 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3045113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31023863 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31023863 — Biomarker: EPHA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPHA5; BSK; EHK1; HEK7; TYRO4
Study 31023863 — Biomarker: EPHA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPHA6; EHK2; HEK12
Study 31023863 — Biomarker: EPHA8 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPHA8; EEK; HEK3; KIAA1459
Study 26099758 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 21142269 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 21142269 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9022117 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7910235 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29985964 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27129624 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 24803825 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24803825 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22044195 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20488410 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 15951469 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 7854523 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30295721 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 26380437 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 26380437 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26380437 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26380437 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26380437 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8039530 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 2688711 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)