AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 21738622 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 12507707 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31618540 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15277331 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 8301727 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 23415171 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16948481 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27757803 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 11477202 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 7978176 — Biomarker: NELFCD mRNA
Type: Predictive Biomarker (PRD)
Genes: NELFCD; NELFD; TH1; TH1L; HSPC130
Study 23593327 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20621562 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24798767 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20362710 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20362710 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8847861 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1562095 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 6320945 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27042750 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24201089 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24201089 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24201089 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24201089 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22454414 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12490735 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 1938279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28360116 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 24038736 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 22004512 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 27865566 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 15309445 — Biomarker: OGG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OGG1; MMH; MUTM; OGH1
Study 2318105 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12118266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19231545 — Biomarker: STC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STC1; STC
Study 19231545 — Biomarker: NTS mRNA
Type: Predictive Biomarker (PRD)
Genes: NTS
Study 15179026 — Biomarker: DMTN mRNA
Type: Predictive Biomarker (PRD)
Genes: DMTN; DMT; EPB49
Study 16218198 — Biomarker: CR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR2; C3DR
Study 10471456 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18535115 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11103752 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 26062785 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 24940052 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 30844053 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 30844053 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 23184565 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2949585 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29624463 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 19432501 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9745150 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11403539 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 15840681 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 2112184 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 100129 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21910947 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9506749 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30169980 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 30987551 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 30987551 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30987551 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 26802793 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 25942341 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 7719894 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7719894 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 7719894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26955912 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 11209104 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 3398697 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 31920008 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24797760 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24192751 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 7769049 — Biomarker: Proliferation marker protein Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67
Study 19285833 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19285833 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11463772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9879155 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 31028038 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 12002198 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 11422108 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 11422108 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28645949 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28645949 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 21445287 — Biomarker: SELENOW mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENOW; SELW; SEPW1
Study 19419670 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 11509081 — Biomarker: DDC mRNA
Type: Predictive Biomarker (PRD)
Genes: DDC; AADC
Study 26834211 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22176998 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21519359 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21519359 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16278367 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 12709719 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 23043563 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9737475 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 7921469 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 23230135 — Biomarker: NCOA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NCOA3; AIB1; BHLHE42; RAC3; TRAM1
Study 23230135 — Biomarker: PAX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAX2
Study 30712740 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 1357152 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1357152 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 29566934 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 29566934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26272586 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 24819761 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 11801426 — Biomarker: SNAP25 mRNA
Type: Predictive Biomarker (PRD)
Genes: SNAP25; SNAP
Study 15374060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30753625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18987053 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8616760 — Biomarker: PGR mRNA
Type: Predictive Biomarker (PRD)
Genes: PGR; NR3C3
Study 22708917 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 10364997 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 1911428 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 1911428 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 29099947 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22776430 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 28398692 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9042130 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2835964 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25645567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25645567 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25645567 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23870798 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23870798 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18855244 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29968686 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29968686 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22953754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25277459 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 19201295 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 9536833 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2397544 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 23787550 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 29317896 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 29317896 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 23590265 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 21149654 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 18348888 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 18348888 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 10866914 — Biomarker: Alpha-glutathione S-transferase
Type: Safety Biomarker (SAF)
Study 2876573 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 2876573 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22622452 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8773915 — Biomarker: Interleukin 1 alpha
Type: Safety Biomarker (SAF)
Genes: IL1A; IL1F1
Study 8773915 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8773915 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 6560420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20167702 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 20167702 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20167702 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7655833 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24588789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8730431 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 27068631 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27068631 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17916078 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10322043 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 9086318 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9086318 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9086318 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2019135 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31841599 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 31841599 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 21211560 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 18753466 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 11353965 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11353965 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 31300879 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 31300879 — Biomarker: FGG mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGG; PRO2061
Study 18458163 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11191537 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21664286 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19403950 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 12401850 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9832182 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15233837 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9241548 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9241548 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 24806568 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25810595 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 29526457 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29526457 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 10606935 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 1501967 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 27143319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23726630 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14759617 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 9778666 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 28342967 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12816748 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 20629630 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31675621 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 23895631 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 19153263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12684362 — Biomarker: CNTF mRNA
Type: Predictive Biomarker (PRD)
Genes: CNTF
Study 30109404 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 18751689 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 17900462 — Biomarker: ADCY10 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADCY10; SAC
Study 15006018 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 27113485 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 27113485 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 27113485 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24168514 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 18343261 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16299878 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 12572927 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8521118 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 30969260 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 29716784 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 19641360 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 17469136 — Biomarker: PTK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTK2; FAK; FAK1
Study 17469136 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 17469136 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 26921523 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 26921523 — Biomarker: ITFG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITFG1; LNKN-1; TIP; CDA08
Study 25117466 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18019394 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 22673937 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22673937 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22673937 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 17634479 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17634479 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 17634479 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 17634479 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22398088 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20196149 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20196149 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9348446 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 15081453 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19722799 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 11572292 — Biomarker: TPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH1; TPH; TPRH; TRPH
Study 9280178 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 9280178 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8393884 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3089519 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16298441 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16298441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9109757 — Biomarker: INVS mRNA
Type: Predictive Biomarker (PRD)
Genes: INVS; INV; NPHP2
Study 25540298 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 12571159 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 8174967 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 8174967 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 25398288 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25398288 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17577462 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12542882 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 31301293 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 31301293 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25329681 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 7539635 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7539635 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 7539635 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 18563062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)