AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 28089080 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7810174 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 26271331 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2412037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10870980 — Biomarker: KCNN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNN1; SK
Study 31200092 — Biomarker: OXTR mRNA
Type: Predictive Biomarker (PRD)
Genes: OXTR
Study 28403972 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25450717 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 16186262 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10769584 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6496919 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 16754631 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8793794 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 8793794 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 8793794 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8793794 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8793794 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 20713433 — Biomarker: OGG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OGG1; MMH; MUTM; OGH1
Study 20713433 — Biomarker: NUDT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUDT1; MTH1
Study 20713433 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 2151518 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31667917 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 31667917 — Biomarker: OSBPL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: OSBPL5; KIAA1534; OBPH1; ORP5
Study 21297567 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16720746 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10406241 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 2119897 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 7228446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26022813 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 26022813 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26022813 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21173357 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12602423 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 10430816 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25029675 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19056578 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 9535429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29436337 — Biomarker: TNFRSF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1A; TNFAR; TNFR1
Study 29436337 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26241700 — Biomarker: CYP24A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP24A1; CYP24
Study 26241700 — Biomarker: CYP27B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 11736860 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 11736860 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 22661750 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 22661750 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22070095 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22070095 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 26717361 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21416235 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 19196218 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 19196218 — Biomarker: TNFA
Type: Predictive Biomarker (PRD)
Genes: TNF; TNFSF2; DIF; TNF-alpha
Study 12575494 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 25823271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21484319 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 15104658 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31678965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30137352 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21292633 — Biomarker: RXRA mRNA
Type: Predictive Biomarker (PRD)
Genes: RXRA; NR2B1
Study 21292633 — Biomarker: CDC25C mRNA
Type: Predictive Biomarker (PRD)
Genes: CDC25C
Study 21292633 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 12975720 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2856708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30507829 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22688651 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18397971 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14714551 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 14714551 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 10579151 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 8610720 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23452436 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 22295830 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22295830 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20103782 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 16191743 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 16191743 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 30400939 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 11607795 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11607795 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9893735 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7223302 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22313514 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17660026 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11799102 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 11799102 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11799102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7144067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31958286 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31958286 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 20573086 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 20573086 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 16266457 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 2097149 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 31797578 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 31797578 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 16041547 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 16041547 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 16041547 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 16041547 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 12366605 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 20701024 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 20701024 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 20701024 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 8908525 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24265330 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15179645 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 7829634 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 22633793 — Biomarker: SCN8A mRNA
Type: Predictive Biomarker (PRD)
Genes: SCN8A; MED
Study 22633793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17019548 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 28643056 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 20724647 — Biomarker: C12orf57 mRNA
Type: Predictive Biomarker (PRD)
Genes: C12orf57; C10
Study 20724647 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 15709187 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 12566371 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12566371 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12566371 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 6414822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9204360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24626975 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 31604654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31604654 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24619062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24619062 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10441974 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8527276 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21234550 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17095973 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31449829 — Biomarker: MZB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MZB1; MEDA7; PACAP; HSPC190
Study 24227738 — Biomarker: MAP3K10 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP3K10; MLK2; MST
Study 19922129 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12599012 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 3534847 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30174281 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30174281 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 30174281 — Biomarker: PON3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON3
Study 30174281 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 29933529 — Biomarker: CHM mRNA
Type: Predictive Biomarker (PRD)
Genes: CHM; REP1; TCD
Study 12012078 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25069199 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19958429 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15320674 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15320674 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 3103436 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29924041 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19853454 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 19056618 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 17697359 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17697359 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 17697359 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 9745419 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9745419 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 4043604 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30480640 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 29433578 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29433578 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 15130084 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 30217958 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21092710 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21092710 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21092710 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2302870 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 19282350 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 3472436 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10952095 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 21693723 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19625240 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2773832 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31407195 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23756230 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 23756230 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17059385 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28661435 — Biomarker: EMP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EMP1; B4B; TMP
Study 23900048 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 18978612 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21276534 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10992369 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 7671058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18498003 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 15114776 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15114776 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28590143 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28590143 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 8369100 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 29743087 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 11590509 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28560782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11451214 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31048638 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 14972421 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11519636 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9762776 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 31650181 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31650181 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24126646 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 12975595 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1587378 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 3983885 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24851869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18593851 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18593851 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 18593851 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18593851 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 12445027 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 30701554 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30701554 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30701554 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29021123 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 25439709 — Biomarker: PRKRA mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKRA; PACT; RAX; HSD-14; HSD14
Study 15356039 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15356039 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16636217 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16636217 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16636217 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29097056 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23257680 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 23257680 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 23257680 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11800416 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17374659 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25596571 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23275387 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 23275387 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study 15168386 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26606887 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 22042368 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22042368 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 15834298 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25721698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23874597 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7933819 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2952091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29807477 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 12359039 — Biomarker: MAOB mRNA
Type: Predictive Biomarker (PRD)
Genes: MAOB
Study 10427455 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29852877 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 28255797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22933442 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8256898 — Biomarker: HRC mRNA
Type: Predictive Biomarker (PRD)
Genes: HRC; HCP
Study 25516481 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 20338978 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19001206 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16308009 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 10553845 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 10553845 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8875693 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 8875693 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 8875693 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29032393 — Biomarker: VHL mRNA
Type: Predictive Biomarker (PRD)
Genes: VHL
Study 29032393 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR