AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 26901353 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 25105388 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 15115259 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 15115259 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15115259 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 22099889 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10637255 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10637255 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29094434 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29094434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16417414 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16417414 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 16417414 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16417414 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 9489309 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22290668 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31465307 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 18375410 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 9129845 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29990442 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 29934046 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 29934046 — Biomarker: Mitochondrial membrane potential
Type: Pharmacodynamic Biomarker (PDY)
Study 25151398 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 25151398 — Biomarker: ADGRE5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADGRE5; CD97
Study 25151398 — Biomarker: TNFRSF9 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF9; CD137; ILA
Study 18403130 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10100083 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10100083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6439360 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31369593 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24172160 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 22038336 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 19270108 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23141748 — Biomarker: IFIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFIT1; G10P1; IFI56; IFNAI1; ISG56
Study 23141748 — Biomarker: IFI44 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFI44; MTAP44
Study 17160910 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 17160910 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 9058494 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 21934521 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 18600212 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11898913 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 11898913 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18532873 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15378284 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8570977 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2240627 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9041945 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3503941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8919897 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 8919897 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7051805 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 7051805 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 27704143 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21878488 — Biomarker: RHD mRNA
Type: Predictive Biomarker (PRD)
Genes: RHD
Study 7923304 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31465093 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 31465093 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29113664 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 25350224 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 24267513 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17187417 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 26077412 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26077412 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15367067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10879554 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 30487976 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23899653 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23899653 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10426331 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 19185400 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 19185400 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 6786825 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23770110 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 8908377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6126126 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8137435 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 8137435 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21155616 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21155616 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21155616 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12490768 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 25480461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17570513 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12187208 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 22820210 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 19083502 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16562817 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29528443 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 24760645 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20231783 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 20231783 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 31504417 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 31504417 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20171327 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 21871624 — Biomarker: KIF6 mRNA
Type: Predictive Biomarker (PRD)
Genes: KIF6; C6orf102
Study 15097153 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10696916 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 10696916 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10696916 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 10696916 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 30871349 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 22015082 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 7527106 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20962664 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 20962664 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 15541248 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11853286 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22615116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20666265 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 20666265 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 11804978 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 31375380 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31375380 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 20054294 — Biomarker: KCNJ11 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNJ11
Study 20054294 — Biomarker: TCF7L2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCF7L2; TCF4
Study 1414144 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 28294535 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 17577460 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10326113 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10326113 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 7653825 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2551088 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11277173 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 11277173 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9863499 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9863499 — Biomarker: A1CF mRNA
Type: Predictive Biomarker (PRD)
Genes: A1CF; ACF; ASP
Study 31619234 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27221864 — Biomarker: SULT1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SULT1A1; STP; STP1; OK/SW-cl.88
Study 27221864 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31604589 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 31604589 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 18981188 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 15335180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6387613 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31659655 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10362894 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 14624403 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 22134152 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22134152 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15827896 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15827896 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24124428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19221039 — Biomarker: WT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WT1
Study 19221039 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 19221039 — Biomarker: CEBPA mRNA
Type: Predictive Biomarker (PRD)
Genes: CEBPA; CEBP
Study 19221039 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8181024 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28766349 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20732799 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20732799 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16776849 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 30099402 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 17610527 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17610527 — Biomarker: Alpha-glutathione S-transferase
Type: Safety Biomarker (SAF)
Study 11115156 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9154995 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 8425695 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8425695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3322166 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 3322166 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30243294 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8972000 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 2861219 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24391822 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 24391822 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 7052613 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 25200559 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17725934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12186124 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 100866 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 15131431 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 9649661 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8021472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8021472 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18379218 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 18379218 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 10532588 — Biomarker: CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR1; C3BR
Study 19679580 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7424927 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31699052 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 30113724 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 30113724 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 30113724 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 11594643 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9855387 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16758733 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 10556117 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8561059 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1927294 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 28241822 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 28241822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15031131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31515704 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2943752 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 23752109 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8671965 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 8671965 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1834065 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7134845 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27096878 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24937669 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22190136 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22190136 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20567133 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 20567133 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11130129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18925510 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 8882074 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 1430301 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 3005756 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18319697 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18319697 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 18661258 — Biomarker: Cyclin-dependent kinase inhibitor 1
Type: Safety Biomarker (SAF)
Genes: CDKN1A
Study 27173814 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12552351 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 7546496 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24123094 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 20200041 — Biomarker: KIT
Type: Predictive Biomarker (PRD)
Genes: CD117; SCFR; C-Kit
Study 1415200 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 3905211 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24823465 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 20144231 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20144231 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 18394099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12722398 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 8116037 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8116037 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8116037 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 8116037 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8116037 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 1069551 — Biomarker: MERTK mRNA
Type: Predictive Biomarker (PRD)
Genes: MERTK; MER
Study 30021394 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30021394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30021394 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12492612 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2790218 — Biomarker: RARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RARS1; RARS
Study 21827215 — Biomarker: NR1I2
Type: Predictive Biomarker (PRD)
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 21827215 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 14736787 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 11776596 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 6151506 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23535809 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 15914049 — Biomarker: SRM mRNA
Type: Predictive Biomarker (PRD)
Genes: SRM; SPS1; SRML1
Study 11106307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24519039 — Biomarker: ITPA mRNA
Type: Predictive Biomarker (PRD)
Genes: ITPA; C20orf37; My049; OK/SW-cl.9
Study 10577621 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 3034017 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3034017 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27665708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19567528 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)