AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 29313746 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24122760 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22514150 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 22514150 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18403272 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 26729277 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22851577 — Biomarker: TBC1D4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TBC1D4; AS160; KIAA0603
Study 11879715 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11879715 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7575120 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19279300 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17250692 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7521090 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29664896 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21051493 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9627304 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 14641260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8184807 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28742880 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21710615 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 14764230 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14764230 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31241519 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26260043 — Biomarker: Zinc finger protein GLI1
Type: Predictive Biomarker (PRD)
Genes: GLI1; GLI
Study 19921355 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9672165 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 7729237 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15230999 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8392903 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30807663 — Biomarker: C1QL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 22177371 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 27498098 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 23848972 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 23848972 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20121889 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20121889 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 20121889 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20121889 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6333182 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 31132578 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 29045997 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 29045997 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 25973934 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 22841452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7816383 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 30119757 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24384584 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 8365829 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31833849 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31833849 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31002213 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 16290015 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16290015 — Biomarker: Interleukin 1 alpha
Type: Safety Biomarker (SAF)
Genes: IL1A; IL1F1
Study 16290015 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 16290015 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16290015 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15636308 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15636308 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11376633 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18294484 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8471696 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 20435187 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 20435187 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16335887 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11910308 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20335831 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 11990441 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 1991261 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27290982 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10188789 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 29186759 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29186759 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 26159452 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 23864583 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15262244 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 8993254 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8993254 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8993254 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 8993254 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8993254 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8993254 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25375979 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8691512 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 7049708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7049708 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 30413379 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30413379 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 17460710 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11583728 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11583728 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21700924 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 28708863 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28708863 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 28708863 — Biomarker: ENTPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ENTPD1; CD39
Study 28708863 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 23922114 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 6731327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29187594 — Biomarker: SLC2A9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A9; GLUT9
Study 29187594 — Biomarker: ABCG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 22527829 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16140974 — Biomarker: CCND1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND1; BCL1; PRAD1
Study 16140974 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 16140974 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31956660 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31956660 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26975818 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26975818 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 26975818 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 26975818 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26975818 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 26975818 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 26975818 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 17617283 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17617283 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17617283 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17617283 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23365148 — Biomarker: SGCG mRNA
Type: Predictive Biomarker (PRD)
Genes: SGCG
Study 19127197 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19127197 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29395424 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 9704200 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 20848538 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19194270 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19194270 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 19194270 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 19194270 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 19194270 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 17533020 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 17533020 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9741224 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 2647291 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 18486782 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 17000189 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14558436 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20107199 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2521816 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27299675 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25976063 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31968400 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27600055 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 8833557 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8833557 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8833557 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3886357 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30137218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30137218 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30137218 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30137218 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30137218 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 17045796 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 14751652 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14751652 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9324165 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 12771323 — Biomarker: Apolipoprotein A-IV
Type: Monitoring Biomarker (MOI)
Genes: APOA4
Study 10470628 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8544269 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 31379269 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31379269 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 21586234 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18363087 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 14581419 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 6547563 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 27950666 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 14974922 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10826408 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6149772 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 18407386 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 15764631 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12365325 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2644749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 766574 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15204248 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15204248 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 11579243 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11579243 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8250311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30511959 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 30511959 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23522121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23522121 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25168918 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 9506325 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28875327 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 28390695 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28390695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26301484 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 18499604 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20876734 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 18284057 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 28853509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26378246 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 17558730 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30935545 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25990355 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18752430 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15895329 — Biomarker: C6orf15 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6orf15; STG; UNQ1840/PRO3566
Study 1697836 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 19207321 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 17161821 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 17161821 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 31640794 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 2157313 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29513111 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27003645 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 21556746 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14601477 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 14601477 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 20686486 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18939907 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14515443 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 14515443 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 8879341 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28912447 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17699388 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15507176 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8072077 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 25887660 — Biomarker: ASPSCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 8988823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31892574 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 31892574 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 25736126 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23263721 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 12487852 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 9793223 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 29668990 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 22785552 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 10930484 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23220798 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23220798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23220798 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16544177 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9185636 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9185636 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2969912 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 27525532 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 10353861 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10353861 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 29081179 — Biomarker: ILK mRNA
Type: Predictive Biomarker (PRD)
Genes: ILK; ILK1; ILK2
Study 29081179 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 23438054 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 24669841 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12602460 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26621261 — Biomarker: MMP28 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP28; MMP25; UNQ1893/PRO4339
Study 18082488 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17081360 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 12843739 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4