AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 29142243 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20518178 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 19294863 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 1930916 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6890761 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 31623223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28441856 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28441856 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28441856 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21777884 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 19622627 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16700848 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 2083195 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2083195 — Biomarker: FER mRNA
Type: Predictive Biomarker (PRD)
Genes: FER; TYK3
Study 2083195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30678029 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 25123755 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22190065 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 11994341 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25424464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23029716 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31781682 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31781682 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17113170 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15066944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10921031 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10921031 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 10921031 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 10921031 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25732157 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 17619911 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29382797 — Biomarker: TNFRSF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1A; TNFAR; TNFR1
Study 29382797 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29382797 — Biomarker: TNFRSF1B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1B; TNFBR; TNFR2
Study 25049001 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 21909820 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16380670 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 7037502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21299408 — Biomarker: IMPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IMPA1; IMPA
Study 3312789 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31425480 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31394768 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31394768 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31394768 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31394768 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28607336 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 18513463 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18513463 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 16263768 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 9720838 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 9720838 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 2902379 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31012819 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 10944136 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8100611 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2880655 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 29479645 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23535509 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10978402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21029662 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21029662 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 21029662 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21029662 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21029662 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8934215 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 8934215 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 27471803 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 14578611 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14578611 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31765046 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 15376499 — Biomarker: Ribonucleoside-diphosphate reductase large subunit
Type: Predictive Biomarker (PRD)
Genes: RRM1; RR1
Study 11576376 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11576376 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26137916 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 11410122 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 9390695 — Biomarker: LGSN mRNA
Type: Predictive Biomarker (PRD)
Genes: LGSN; GLULD1; LGS
Study 7829623 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23051740 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21887284 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 21887284 — Biomarker: MMP12 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP12; HME
Study 12846708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1826285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9115060 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1490503 — Biomarker: OMD mRNA
Type: Predictive Biomarker (PRD)
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 27021606 — Biomarker: Vitamin K-dependent protein C
Type: Safety Biomarker (SAF)
Genes: PROC
Study 19952781 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26567123 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 26391130 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26391130 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26391130 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 26391130 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20571360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16614408 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 24621069 — Biomarker: RTN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RTN1; NSP
Study 1720012 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 16439468 — Biomarker: TLR5
Type: Predictive Biomarker (PRD)
Genes: TIL3; FLJ10052; MGC126430; MGC126431
Study 6439286 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6439286 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31714453 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20460227 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31697873 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 9368551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22827512 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15619390 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11871954 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10190266 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 22340428 — Biomarker: GPR119 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPR119
Study 20090397 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 31916571 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 15203290 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 9568752 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3229340 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 3229340 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29514224 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 24691410 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20371584 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 20371584 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8743497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30894658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28835586 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24362944 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19386059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4348345 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4348345 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 27633880 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 27633880 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 11281614 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11281614 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11281614 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7994784 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 15037882 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 10910003 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 23929260 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 8387084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30446405 — Biomarker: PTN mRNA
Type: Predictive Biomarker (PRD)
Genes: PTN; HBNF1; NEGF1
Study 27118620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24572702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11061578 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 8393389 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28947569 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12477620 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12477620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8963482 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 31362531 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30830724 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26469986 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21864886 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 21864886 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19645779 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9141914 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9141914 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7944696 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24144615 — Biomarker: ST8SIA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ST8SIA4; PST; PST1; SIAT8D
Study 18949961 — Biomarker: EHF mRNA
Type: Predictive Biomarker (PRD)
Genes: EHF; ESE3; ESE3B; ESEJ
Study 20977501 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15731987 — Biomarker: BNIP3L mRNA
Type: Predictive Biomarker (PRD)
Genes: BNIP3L; BNIP3A; BNIP3H; NIX
Study 23372145 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20801010 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16177446 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 10664826 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 10664826 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 8863759 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8863759 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 3899672 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 3899672 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 3899672 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3899672 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22287757 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15468717 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15468717 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31543378 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 28178209 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28178209 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28178209 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28178209 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24847155 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 15801953 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 2652176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25781235 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25781235 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25781235 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17100936 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 8090608 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8090608 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 23358966 — Biomarker: Serum asparaginase
Type: Surrogate Endpoint (SUR)
Study 8793703 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8793703 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1465059 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15663123 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 3585450 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 11421896 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 19751115 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9284731 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29537647 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11576319 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11576319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3154680 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27665372 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17879117 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 11039202 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 11039202 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 1603897 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3932142 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 31523892 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 31523892 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 16721398 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16721398 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11167171 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 8361220 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 30104327 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 17338717 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15284015 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 15916853 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 15916853 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 6787909 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29296854 — Biomarker: ADAMTS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 31275597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10866044 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 3033182 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3033182 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22147786 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10886233 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8644400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24058089 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24058089 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 15540744 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 9286889 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 23463656 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8064580 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 3330115 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27503659 — Biomarker: REL mRNA
Type: Predictive Biomarker (PRD)
Genes: REL
Study 22094037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21606948 — Biomarker: CHRNB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNB2
Study 16191054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10684018 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 26024743 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20105189 — Biomarker: GHR mRNA
Type: Predictive Biomarker (PRD)
Genes: GHR
Study 15972580 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8556225 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)