AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 9695717 — Biomarker: CYP2E1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2E1; CYP2E
Study 29721714 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18697911 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 18697911 — Biomarker: RAPGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 9931535 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 26290749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15225192 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 15225192 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15225192 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7838444 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 31974825 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26205910 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 23527521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1947729 — Biomarker: HDC mRNA
Type: Predictive Biomarker (PRD)
Genes: HDC
Study 20050759 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20050759 — Biomarker: FXYD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FXYD1; PLM
Study 9849446 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 365391 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15347709 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15347709 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9504354 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9504354 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9504354 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27488859 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 8977510 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 8977510 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 3912182 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25115616 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25825336 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19574322 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 17726081 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17726081 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21514398 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 21514398 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 12835516 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 30669280 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19175929 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19175929 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17984247 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 19302559 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 29710111 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 27151508 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 20805273 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18579510 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 18579510 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 11833023 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 1703909 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 1703909 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 1703909 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28724962 — Biomarker: NOD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOD2; CARD15; IBD1
Study 28724962 — Biomarker: GBP5 mRNA
Type: Predictive Biomarker (PRD)
Genes: GBP5; UNQ2427/PRO4987
Study 28724962 — Biomarker: IFITM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFITM1; CD225; IFI17
Study 28724962 — Biomarker: TNIP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNIP1; KIAA0113; NAF1
Study 25755034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25755034 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3929308 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29521661 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 8441895 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 25148049 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 20101593 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 20101593 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 20101593 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 3768929 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3768929 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 18565100 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 18565100 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 28683994 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 25712416 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 25767372 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11431228 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9731682 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21085983 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9644320 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 22430270 — Biomarker: TET2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET2; KIAA1546; Nbla00191
Study 20332125 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 8933850 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6992822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6992822 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6992822 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 11056094 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22458601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28987237 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25552526 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17612946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19538486 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 21438413 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 10426383 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 10426383 — Biomarker: PLTP mRNA
Type: Predictive Biomarker (PRD)
Genes: PLTP
Study 10426383 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23381694 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 17522388 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11350844 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3582478 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 31188232 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 19201696 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 10895373 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8777471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30845829 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 19368581 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 15044507 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 15044507 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 6778754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29803838 — Biomarker: STING1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STING1; ERIS; MITA; STING; TMEM173
Study 15707560 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15707560 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1662376 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30724002 — Biomarker: SLC5A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A1; NAGT; SGLT1
Study 30724002 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 29871676 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 27100457 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 2468913 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25853591 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25853591 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 25853591 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 25853591 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 22621750 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 12575377 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12575377 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28408655 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 28408655 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24278992 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 24278992 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24278992 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 17015551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25604900 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 16518347 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 16518347 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1333962 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23246445 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10697395 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10697395 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21918905 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18156033 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 7867676 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21625085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23698160 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 15998758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10574652 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10574652 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1715450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30527555 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19462490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22781864 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 15206496 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15206496 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8207039 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 21296261 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16579706 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16579706 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 16579706 — Biomarker: NANOS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS1; NOS1
Study 16579706 — Biomarker: NANOS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS3; NOS3
Study 16579706 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16579706 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 12928471 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24324045 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19417110 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19417110 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19417110 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 12599230 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 12599230 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10674229 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 8456474 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 3531033 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3531033 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28035345 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 28035345 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 22892813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27630318 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 25158772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12796154 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10860897 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3006981 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 20143382 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 3545579 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3545579 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3545579 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 29664001 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 30807853 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29902295 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29902295 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24840756 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 18931201 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20974558 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 9428493 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 788722 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 24710470 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16103383 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11839141 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7821198 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 7821198 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26749533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20518225 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17505694 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17505694 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27998241 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17974502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10995520 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6437575 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27653164 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27653164 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25483553 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23242248 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9817475 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9817475 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25792492 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 25792492 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23275593 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 21984584 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 16501248 — Biomarker: PRDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRDM2; KMT8; RIZ
Study 16501248 — Biomarker: EHMT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EHMT2; BAT8; C6orf30; G9A; KMT1C; NG36
Study 10894313 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29518488 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29518488 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18622280 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16135476 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16135476 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 16135476 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11812507 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11812507 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11812507 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 10624328 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1935152 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 27804204 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26452988 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 17084252 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8302412 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 30883516 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27093702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24930728 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24930728 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21697747 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21697747 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21697747 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1657799 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1657799 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7041943 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 31603565 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 24975467 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 16083704 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 16083704 — Biomarker: ABCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 16083704 — Biomarker: ABCB4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCB4; MDR3; PGY3
Study 16083704 — Biomarker: ABCC4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC4; MOATB; MRP4
Study 10347293 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10347293 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 24724887 — Biomarker: DBH mRNA
Type: Predictive Biomarker (PRD)
Genes: DBH