AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 30767788 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30767788 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10321444 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21091100 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15144908 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 11977322 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 11977322 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9701895 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 9701895 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 2528983 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19429721 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8750275 — Biomarker: AFM mRNA
Type: Predictive Biomarker (PRD)
Genes: AFM; ALB2; ALBA
Study 27663365 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 27663365 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24785761 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 12406021 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 2139175 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17324285 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 15220185 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12457389 — Biomarker: FURIN mRNA
Type: Predictive Biomarker (PRD)
Genes: FURIN; FUR; PACE; PCSK3
Study 10413652 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10413652 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 29512121 — Biomarker: CXCL1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 29512121 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 21309476 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12088304 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 31950604 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 28283797 — Biomarker: Nqo1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: NQO1; DIA4; NMOR1
Study 28283797 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 21681118 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 10858346 — Biomarker: STAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT1
Study 10858346 — Biomarker: IRF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRF1
Study 10858346 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 10858346 — Biomarker: IRF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRF2
Study 10858346 — Biomarker: PIAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PIAS1; DDXBP1
Study 9200356 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 29733995 — Biomarker: LIPC mRNA
Type: Predictive Biomarker (PRD)
Genes: LIPC; HTGL
Study 16356358 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16356358 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16356358 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8346593 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8346593 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 8346593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27513312 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27513312 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20920126 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16116958 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 24240575 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18302711 — Biomarker: FGFR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR3; JTK4
Study 12462290 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 12462290 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9156883 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9156883 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24907435 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24907435 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22294470 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 22294470 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 9527740 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 19056600 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 15657470 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7962322 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 16652321 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12791811 — Biomarker: NOTCH3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOTCH3
Study 18045712 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18045712 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18045712 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18045712 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2673437 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2931024 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18503891 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 18503891 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 18503891 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 30654925 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9409295 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 9409295 — Biomarker: Vitamin K-dependent protein C
Type: Safety Biomarker (SAF)
Genes: PROC
Study 9409295 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9409295 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 9409295 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8287641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31287236 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 31287236 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 29503060 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 28383434 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28383434 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28383434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17894033 — Biomarker: CPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPB1; CPB; PCPB
Study 17894033 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 15646240 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 11740389 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11740389 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30808949 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30808949 — Biomarker: miR-155
Type: Safety Biomarker (SAF)
Genes: MIR155
Study 23190017 — Biomarker: SYK mRNA
Type: Predictive Biomarker (PRD)
Genes: SYK
Study 16527796 — Biomarker: CTSC mRNA
Type: Predictive Biomarker (PRD)
Genes: CTSC; CPPI
Study 12743003 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15694946 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15694946 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9000657 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 21092506 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 28325070 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 28325070 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21736003 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20137477 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 823586 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 823586 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 26408873 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26408873 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19426396 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 16434264 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 16434264 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15296810 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 31957953 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 31957953 — Biomarker: HPGDS mRNA
Type: Predictive Biomarker (PRD)
Genes: HPGDS; GSTS; PGDS; PTGDS2
Study 28274234 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 3139019 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 25850462 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11171825 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28895981 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17497438 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14767720 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 31467115 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 12839661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12839661 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9374151 — Biomarker: TICAM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TICAM2; TIRAP3; TIRP; TRAM
Study 27025241 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 27025241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17217715 — Biomarker: CHD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHD2
Study 17217715 — Biomarker: CHD3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHD3
Study 1583434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29480324 — Biomarker: SLCO1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 29480324 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20969457 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20969457 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 20969457 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 20969457 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11348882 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11348882 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 8392282 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8392282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20832103 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19062727 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8554224 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 6129951 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30439785 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 30439785 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28549319 — Biomarker: FGG mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGG; PRO2061
Study 27083334 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 11349825 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23276469 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23276469 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23276469 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 14985966 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9438269 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 16940452 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16940452 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21295363 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 12100223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15477790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26489704 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24964689 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 24964689 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12195170 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 30496493 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 30496493 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 21998121 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8938674 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30690930 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 25632744 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 17221296 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12201354 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9989963 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2156343 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 2156343 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7030636 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2844641 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31743131 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 26193861 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26193861 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12627316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11114637 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 26923987 — Biomarker: BMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BMP2; BMP2A
Study 26923987 — Biomarker: BMP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: BMP7; OP1
Study 25529979 — Biomarker: SLC5A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A1; NAGT; SGLT1
Study 25529979 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 26615369 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25295770 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11584376 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 3279350 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 29426379 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 24112810 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18029109 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18029109 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10592457 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 15753541 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29843467 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 11450476 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31710844 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31106548 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31106548 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31106548 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31106548 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21161263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20031019 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 3396574 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30305115 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30305115 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30305115 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 30305115 — Biomarker: Epithelial cadherin
Type: Predictive Biomarker (PRD)
Genes: CDH1; CDHE; UVO
Study 30305115 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 30305115 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 30305115 — Biomarker: LAMA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA2; LAMM
Study 30305115 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 30305115 — Biomarker: MAP3K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP3K1; MAPKKK1; MEKK; MEKK1
Study 28973220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23427068 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17106197 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27656713 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21675061 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 14767999 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 11416710 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25675385 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17944658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15887898 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6388253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29324864 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 29324864 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 29324864 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24186565 — Biomarker: CFI mRNA
Type: Predictive Biomarker (PRD)
Genes: CFI; IF
Study 2681675 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 31419272 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12675873 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8812622 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25335327 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 16252735 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8954418 — Biomarker: KY mRNA
Type: Predictive Biomarker (PRD)
Genes: KY
Study 26783095 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 26783095 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 19376789 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 9747866 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 9747866 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25614597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)