AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 3993558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10546234 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28802789 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 21211004 — Biomarker: AMPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMPD1
Study 19122556 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17223209 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17223209 — Biomarker: APLNR mRNA
Type: Predictive Biomarker (PRD)
Genes: APLNR; AGTRL1; APJ
Study 3202400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29167951 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 23146410 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31590967 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8069190 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 25162916 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21904641 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17942871 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 14506092 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 14506092 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31059974 — Biomarker: TK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TK1
Study 27856267 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24642580 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 21748722 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21748722 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25730649 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 10735784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22455412 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 15679722 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8774258 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18047871 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 1300856 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31362729 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9880451 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7720346 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7720346 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 2187723 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23077973 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20693243 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18825368 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 17052901 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 15288384 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 15288384 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 21079803 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 8993764 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 23775007 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 23775007 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 8896099 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 2050831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25299501 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 25299501 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 16832133 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23497032 — Biomarker: SP9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP9
Study 3528612 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 29370120 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29370120 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 27196148 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12692753 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12692753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10750754 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10750754 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 8959161 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 2933253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8260897 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 28060360 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 28060360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23348981 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 17973947 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 17973947 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12862363 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6889218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20028707 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10506666 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 26254087 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18513638 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18513638 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12556736 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10898419 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1331023 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20520820 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12455077 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25557316 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 27902833 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 25804495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25804495 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 21389626 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21389626 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21389626 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 15552163 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15257184 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9814456 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9814456 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 24621836 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 3240634 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 3240634 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 31621251 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 23305349 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23305349 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2894980 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26320403 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 6338693 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6338693 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30762895 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 30762895 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 21900844 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9708659 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31924513 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25315667 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9160916 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8105773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3114306 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3114306 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 8623945 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 6378105 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29373753 — Biomarker: TARBP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TARBP2; TRBP
Study 23106878 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 19811509 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 18626271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16143742 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 31554388 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 7850816 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24377221 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 24377221 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21278214 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study 15542278 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 2258782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19615653 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 7925510 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7925510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2810673 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2810673 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31089256 — Biomarker: PRPH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRPH2; PRPH; RDS; TSPAN22
Study 12238845 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12238845 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26409698 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 24129363 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21693504 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15580194 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9201877 — Biomarker: PPIH mRNA
Type: Predictive Biomarker (PRD)
Genes: PPIH; CYP20; CYPH
Study 18261537 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18261537 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study 18261537 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15842584 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 8462363 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8462363 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 26911132 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20147968 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20147968 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9383694 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9122864 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9351684 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8222740 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 29617180 — Biomarker: TPSG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPSG1; PRSS31; TMT
Study 30412147 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 26891754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12507361 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 9771950 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 25526495 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 18665360 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 15095035 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8788313 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 8788313 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 20031834 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31434552 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24812894 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15939067 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 15939067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11788467 — Biomarker: NOS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOS2; NOS2A
Study 11788467 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30893292 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 18047518 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 29308759 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7532763 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31410659 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31410659 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28492898 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 2913892 — Biomarker: STC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STC1; STC
Study 27908689 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 31804005 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 16652130 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10207236 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 7882472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21372490 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24835842 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12176948 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 18632210 — Biomarker: CPD mRNA
Type: Predictive Biomarker (PRD)
Genes: CPD
Study 11061779 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11061779 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27933703 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 27933703 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 23049087 — Biomarker: DTL mRNA
Type: Predictive Biomarker (PRD)
Genes: DTL; CDT2; CDW1; DCAF2; L2DTL; RAMP
Study 23049087 — Biomarker: LGI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LGI1; EPT; UNQ775/PRO1569
Study 15186955 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15186955 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 15186955 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 9000658 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30124473 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26702772 — Biomarker: CACNA1G mRNA
Type: Predictive Biomarker (PRD)
Genes: CACNA1G; KIAA1123
Study 26702772 — Biomarker: IGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF2; PP1446
Study 26702772 — Biomarker: RUNX3 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX3; AML2; CBFA3; PEBP2A3
Study 26702772 — Biomarker: SOCS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOCS1; SSI1; TIP3
Study 22418243 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 1878587 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27134249 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24373927 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22775078 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31128958 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15940046 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11899820 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8590154 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30970655 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23839583 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16888272 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8844019 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8844019 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1636624 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31296491 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 21775563 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19957549 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15386934 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15386934 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31590930 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26424549 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18824930 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7710444 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29096631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20309694 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8891888 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 8891888 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 8891888 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6603074 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31101732 — Biomarker: ADCY10 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADCY10; SAC
Study 16126804 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15071015 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8044782 — Biomarker: DNA topoisomerase I
Type: Pharmacodynamic Biomarker (PDY)
Genes: TOP1
Study 27816302 — Biomarker: ELF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELF4; ELFR; MEF
Study 27816302 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24788581 — Biomarker: MAP3K10 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP3K10; MLK2; MST
Study 17062365 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17062365 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 17062365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2124470 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31022160 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31022160 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31022160 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 24419562 — Biomarker: SLCO1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 24419562 — Biomarker: SLCO2B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 9918907 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20306476 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 10084467 — Biomarker: ARID3B mRNA
Type: Predictive Biomarker (PRD)
Genes: ARID3B; BDP; DRIL2
Study 9738692 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20051692 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 10225069 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8952812 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8519216 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31140940 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1