AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23037494 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 17312305 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28367845 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 28367845 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23537071 — Biomarker: UCP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP2; SLC25A8
Study 10849265 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 30093216 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28612668 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27481077 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 16478747 — Biomarker: MDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM2
Study 16478747 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 19720877 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19720877 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17251533 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 11743591 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8573808 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28295931 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23537330 — Biomarker: TRAPPC9 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 23537330 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 23537330 — Biomarker: SCN8A mRNA
Type: Predictive Biomarker (PRD)
Genes: SCN8A; MED
Study 23537330 — Biomarker: RRAD mRNA
Type: Predictive Biomarker (PRD)
Genes: RRAD; RAD
Study 15327406 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 15327406 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7950181 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16167916 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12763376 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 8843176 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8843176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8843176 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8843176 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30626611 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 30335579 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24810491 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2974715 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2974715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22794117 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22794117 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 20829713 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20829713 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26271677 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 22474401 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16229850 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 16229850 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6608419 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 31951305 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1405328 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 1405328 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 27468542 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27468542 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27468542 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17556425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16224653 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16224653 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9467547 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17705694 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23218821 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 23218821 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 21777702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21777702 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15497363 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 2360388 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 222145 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11728761 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9205018 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 21712498 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18279940 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 29523823 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 27388012 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 24973281 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 11999456 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 788907 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30531382 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 30531382 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 30531382 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30531382 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30531382 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30531382 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 24013702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20019909 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8061262 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 779920 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15627814 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 15627814 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10480519 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 10480519 — Biomarker: PTPRN mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRN; ICA3; ICA512
Study 31627905 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 28805045 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23286405 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 16286871 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12077712 — Biomarker: TAP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAP2; ABCB3; PSF2; RING11; Y1
Study 12077712 — Biomarker: HLA-DQB1
Type: Safety Biomarker (SAF)
Genes: IDDM1; CELIAC1
Study 12077712 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 30015059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19230172 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19230172 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 19230172 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 348614 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25289713 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 22948944 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11228485 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11228485 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7846210 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7846210 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31642331 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 31642331 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 14624184 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28760425 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23731375 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 20090566 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 16364710 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2151046 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29380232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26655582 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 22253252 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 11981352 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 28401821 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28401821 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 20175799 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 20175799 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27027916 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 24410738 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7535443 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7535443 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 29329484 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24525954 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19887114 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18413220 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15707470 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10639526 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 1332988 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 27187898 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 26458126 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 14740954 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14740954 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 14740954 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 14740954 — Biomarker: GZMB mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: GZMB; CGL1; CSPB; CTLA1; GRB
Study 3007250 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30420291 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 23913440 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 22773704 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22773704 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11908555 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 28838276 — Biomarker: ZBTB7A mRNA
Type: Predictive Biomarker (PRD)
Genes: ZBTB7A; FBI1; LRF; ZBTB7; ZNF857A
Study 27391795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7560247 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30370658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11430394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14607663 — Biomarker: PCBD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCBD1; DCOH; PCBD
Study 9502522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31218636 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30538533 — Biomarker: LSS mRNA
Type: Predictive Biomarker (PRD)
Genes: LSS; OSC
Study 22863164 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9177613 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28093466 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25887580 — Biomarker: STC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STC1; STC
Study 9661616 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 31375426 — Biomarker: HDAC9 mRNA
Type: Predictive Biomarker (PRD)
Genes: HDAC9; HDAC7; HDAC7B; HDRP; KIAA0744; MITR
Study 8187303 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 8187303 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17059437 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 17059437 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 27142044 — Biomarker: PLXNA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 17852781 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 23680334 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16540959 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16540959 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 16540959 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 24285687 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 24285687 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22966824 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19921083 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22364258 — Biomarker: miR-34a
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR34A
Study 22364258 — Biomarker: miR-9
Type: Safety Biomarker (SAF)
Study 22364258 — Biomarker: miR-132
Type: Pharmacodynamic Biomarker (PDY)
Genes: MIR132
Study 22364258 — Biomarker: miR-181a
Type: Safety Biomarker (SAF)
Study 12182261 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30113919 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30113919 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 30113919 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 30113919 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 24816724 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 12136612 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 2181860 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31461138 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 30892045 — Biomarker: Apolipoprotein A-IV
Type: Monitoring Biomarker (MOI)
Genes: APOA4
Study 30892045 — Biomarker: Apolipoprotein C-II
Type: Monitoring Biomarker (MOI)
Genes: APOC2; APC2
Study 30892045 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 28731882 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25559798 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25559798 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18771979 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 10202365 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 447034 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20650652 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19812228 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10975586 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 10975586 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 20832963 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 28911155 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28911155 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 23326188 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23326188 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 17614029 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 16931511 — Biomarker: RAPSN mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPSN; RNF205
Study 28911092 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28911092 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28911092 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 20579848 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20579848 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18226768 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20102347 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 20102347 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20102347 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31611264 — Biomarker: Neurofilament light polypeptide
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: NEFL; NF68; NFL
Study 25595138 — Biomarker: C-C motif chemokine 7
Type: Predictive Biomarker (PRD)
Genes: CCL7; MCP3; SCYA6; SCYA7
Study 25595138 — Biomarker: C-C motif chemokine 4
Type: Monitoring Biomarker (MOI)
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 25595138 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25595138 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 25595138 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 7587605 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25749543 — Biomarker: DSP mRNA
Type: Predictive Biomarker (PRD)
Genes: DSP
Study 24535377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15807926 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 10447136 — Biomarker: EMB mRNA
Type: Predictive Biomarker (PRD)
Genes: EMB
Study 25751300 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25751300 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25751300 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 25751300 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24121698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17099514 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17099514 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 14715354 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1802636 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 8606066 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1533606 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 1533606 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16221550 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 16221550 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1