AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 26376093 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 23650408 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23868287 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 24415868 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 23111478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24224448 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19540392 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19540392 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 9550641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30291011 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 30291011 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 24375223 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 8831596 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30916161 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30916161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28451529 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 23046735 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23046735 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11736864 — Biomarker: CYP2E1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2E1; CYP2E
Study 11736864 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 9431858 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30415082 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25441015 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23530962 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23530962 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 21784145 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21784145 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15310688 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9627297 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3229297 — Biomarker: L-acetylcarnitine
Type: Safety Biomarker (SAF)
Study 28944646 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26674200 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 26674200 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25459392 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 20730060 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20730060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20730060 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 16183682 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10391093 — Biomarker: Alpha-glutathione S-transferase
Type: Safety Biomarker (SAF)
Study 8873228 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 24584876 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 22965699 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19575284 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18845709 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10202165 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30703643 — Biomarker: FTL mRNA
Type: Predictive Biomarker (PRD)
Genes: FTL
Study 23553151 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22162988 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30045595 — Biomarker: LSS mRNA
Type: Predictive Biomarker (PRD)
Genes: LSS; OSC
Study 30045595 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 11849795 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 11849795 — Biomarker: Cyclin-dependent kinase inhibitor 1
Type: Safety Biomarker (SAF)
Genes: CDKN1A
Study 30639581 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 27966572 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27966572 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21371681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19265544 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15173725 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15173725 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 15173725 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 15173725 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30789855 — Biomarker: AOX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AOX1; AO
Study 22921446 — Biomarker: AOX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AOX1; AO
Study 18496812 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 9852408 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 29877679 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29877679 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 24849105 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 20367667 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 9803985 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8056004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31315733 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7932194 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31980416 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 24662296 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26884557 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 22268183 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9809926 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 2692838 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31145281 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31145281 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27008585 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23637279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12819323 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12819323 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25308300 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 17164728 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9407377 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 3309901 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 21449914 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 21449914 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 16390852 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16390852 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16390852 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29941296 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 29941296 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23378456 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 19350339 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18242076 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 8576842 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2909202 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30703258 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19514864 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31517745 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 31517745 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 26384014 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28923751 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20530934 — Biomarker: SLC22A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A5; OCTN2
Study 15111485 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9041099 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 8282745 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 17374416 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11427637 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9531074 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20031846 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17802891 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 14977388 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24585100 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 23801303 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23801303 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 23801303 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23801303 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19038708 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 12822744 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10693711 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8794412 — Biomarker: ALPK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALPK1; KIAA1527; LAK
Study 8794412 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 3522507 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 18588760 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 12069285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7830033 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7830033 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7830033 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 31915696 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26048342 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8489054 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2442553 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26525271 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12885371 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12885371 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12885371 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1796634 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 30153634 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 30153634 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 11453889 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9509448 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 3183367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26554758 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 26554758 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26554758 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 26554758 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26554758 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26333496 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 21613574 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 1552057 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 22149257 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 22149257 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 22149257 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 18794727 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 12127877 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12127877 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8545872 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28928048 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26193635 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1442581 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20087375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11799500 — Biomarker: TBP mRNA
Type: Predictive Biomarker (PRD)
Genes: TBP; GTF2D1; TF2D; TFIID
Study 10624956 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 28975821 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29148893 — Biomarker: ETV6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV6; TEL; TEL1
Study 29148893 — Biomarker: RUNX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX1; AML1; CBFA2
Study 28025434 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20567999 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31657594 — Biomarker: MME mRNA
Type: Predictive Biomarker (PRD)
Genes: MME; EPN
Study 23650792 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23650792 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23650792 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11123499 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 14641990 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 1686851 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1686851 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30047502 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11407649 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 7528949 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29495908 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19715976 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19715976 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11021450 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31120674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15276091 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15162466 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 10985600 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10985600 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19541594 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19541594 — Biomarker: COL1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL1A1
Study 19541594 — Biomarker: CDKN1C mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN1C; KIP2
Study 19541594 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 19541594 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10321661 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 7840824 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 7840824 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27575584 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18680695 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study 29075780 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 29075780 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29075780 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 29075780 — Biomarker: Epiregulin
Type: Safety Biomarker (SAF)
Genes: EREG
Study 29075780 — Biomarker: Amphiregulin
Type: Safety Biomarker (SAF)
Genes: AREG; AREGB; SDGF
Study 25060415 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12870120 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12870120 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 12870120 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17597711 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 11783195 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 27398918 — Biomarker: Lysosomal alpha-glucosidase
Type: Safety Biomarker (SAF)
Genes: GAA
Study 25375311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12757534 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 12757534 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 11509470 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30457060 — Biomarker: FKBP5 mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: FKBP5; AIG6; FKBP51
Study 28431559 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 26562755 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 20708858 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8394538 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22948897 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14602541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10448261 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 10448261 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 31557067 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 18263674 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 16816559 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11068941 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 11068941 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 11068941 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11068941 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2441163 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2441163 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 2441163 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26242149 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23108194 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23108194 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 23108194 — Biomarker: VCAM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VCAM1
Study 23108194 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 20530282 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 20530282 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 20530282 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 18222261 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 14688950 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA