AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 20478035 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12909392 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 1858191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17359515 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12040967 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12040967 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1699337 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 1699337 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 25748830 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 17520465 — Biomarker: CPOX mRNA
Type: Predictive Biomarker (PRD)
Genes: CPOX; CPO; CPX
Study 10221357 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14615471 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 1541787 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 1541787 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 3872835 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28961380 — Biomarker: ALPP mRNA
Type: Predictive Biomarker (PRD)
Genes: ALPP; PLAP
Study 21492764 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21492764 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8889317 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1824585 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6407438 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 1832344 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1832344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20658820 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 15557136 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1686784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29882087 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 29882087 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23075703 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20574412 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9932566 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31298337 — Biomarker: SOX11 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOX11
Study 31298337 — Biomarker: miR-31
Type: Predictive Biomarker (PRD)
Genes: MIR31
Study 8063651 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 11529248 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 11529248 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17766699 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 10634921 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 10634921 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 30795731 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 25564476 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 20939064 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16710253 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16710253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29504258 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 29504258 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21092504 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10543576 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22100966 — Biomarker: ADAM11 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ADAM11; MDC
Study 22100966 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 16298235 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 10757578 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19954777 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19954777 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19954777 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8996129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27436668 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 22677927 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22677927 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22677927 — Biomarker: Hypoxia-inducible factor 1-alpha
Type: Predictive Biomarker (PRD)
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 18262758 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18262758 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16874160 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 16874160 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27412942 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27412942 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27412942 — Biomarker: miR-155
Type: Safety Biomarker (SAF)
Genes: MIR155
Study 27412942 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 27412942 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17565578 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 17565578 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 12466345 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8533868 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2148278 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31117100 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC
Study 1824654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22168752 — Biomarker: C-X-C motif chemokine 11
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 22168752 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 22168752 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 20156896 — Biomarker: NRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRP1; NRP; VEGF165R
Study 11840224 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11840224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30473033 — Biomarker: DCC mRNA
Type: Predictive Biomarker (PRD)
Genes: DCC; IGDCC1
Study 26681677 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11512193 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 318493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19214120 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1915428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31409515 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 31409515 — Biomarker: ABCG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG1; ABC8; WHT1
Study 23359232 — Biomarker: SPTB mRNA
Type: Predictive Biomarker (PRD)
Genes: SPTB; SPTB1
Study 21546436 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 15554358 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study 7965282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29149349 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study 18277180 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18277180 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18277180 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18277180 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 1348916 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21552672 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11704374 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22852059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29435729 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 8875971 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31336654 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 31336654 — Biomarker: SLC6A7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A7; PROT
Study 31336654 — Biomarker: FMOD mRNA
Type: Predictive Biomarker (PRD)
Genes: FMOD; FM; SLRR2E
Study 12434648 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9884251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9884251 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7640495 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 7640495 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 19494484 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18037816 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 8131770 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25336745 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 18606901 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18606901 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1352050 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 3540025 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 29126396 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 29126396 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 24157432 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18510068 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16513672 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 16513672 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11983727 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 9806692 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 22475819 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2044648 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29460509 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 20042191 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 20042191 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 20042191 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16043121 — Biomarker: CXCR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR3; GPR9
Study 28131045 — Biomarker: TRAF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRAF3; CAP-1; CRAF1; TRAFAMN
Study 28131045 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 28131045 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 28131045 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24961021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20074751 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 20074751 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 3306508 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 12840859 — Biomarker: CLYBL mRNA
Type: Predictive Biomarker (PRD)
Genes: CLYBL; CLB
Study 12840859 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 30794304 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28130552 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 28130552 — Biomarker: MAPK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK1; ERK2; PRKM1; PRKM2
Study 28130552 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 28130552 — Biomarker: RUNX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX2; AML3; CBFA1; OSF2; PEBP2A
Study 28130552 — Biomarker: MAPK7 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK7; BMK1; ERK5; PRKM7
Study 28130552 — Biomarker: NFKB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NFKB1
Study 28130552 — Biomarker: ITGB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB1; FNRB; MDF2; MSK12
Study 28130552 — Biomarker: PPARG mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARG; NR1C3
Study 28130552 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 28130552 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2205379 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19158369 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 26656981 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 8223165 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24962666 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 9877147 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8560416 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 8560416 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 31862312 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31862312 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 31862312 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30690191 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 26644202 — Biomarker: LINGO2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LINGO2; LERN3; LRRN6C; UNQ9234/PRO31993
Study 26644202 — Biomarker: IMPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IMPA1; IMPA
Study 26644202 — Biomarker: DUSP26 mRNA
Type: Predictive Biomarker (PRD)
Genes: DUSP26; DUSP24; LDP4; MKP8; NATA1; SKRP3
Study 26644202 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23459854 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19394034 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11550168 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 11550168 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 27627981 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17711908 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 7968874 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7968874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27770114 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27770114 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22116817 — Biomarker: STAT5A mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT5A; STAT5
Study 20858400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11253476 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 30904178 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30904178 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1358118 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31465088 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31465088 — Biomarker: VEGF
Type: Predictive Biomarker (PRD)
Genes: VEGFA; VEGF-A; VPF
Study 31465088 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23122916 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 19351753 — Biomarker: FGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF2; FGFB
Study 19351753 — Biomarker: FGFR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 19351753 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30678199 — Biomarker: MGP mRNA
Type: Predictive Biomarker (PRD)
Genes: MGP; MGLAP; GIG36
Study 27127102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22904136 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 20399059 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20399059 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15800995 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15800995 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12876093 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12876093 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12876093 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8681494 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2071560 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 26138292 — Biomarker: CXCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR5; BLR1; MDR15
Study 26138292 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9177364 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 8463521 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 29864418 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 29864418 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 20049951 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 18720362 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18720362 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16253102 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 12381079 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20577130 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17434094 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16315822 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 19925464 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17884451 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 17884451 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17884451 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 31340979 — Biomarker: PLA2R1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2R1; CLEC13C
Study 31340979 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 19884620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15279619 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15279619 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11157183 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25573751 — Biomarker: SLC22A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A2; OCT2
Study 22244715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1443704 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31992758 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31992758 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31992758 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23636469 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 18334144 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 16799817 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30371283 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3