AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31362785 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 31362785 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10210340 — Biomarker: ADAM17 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM17; CSVP; TACE
Study 1905474 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1905474 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 27857189 — Biomarker: KCNQ1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNQ1; KCNA8; KCNA9; KVLQT1
Study 24075865 — Biomarker: VIT mRNA
Type: Predictive Biomarker (PRD)
Genes: VIT; UNQ647/PRO1277
Study 20082624 — Biomarker: GLS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS2; GA
Study 10915227 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24811095 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 7843758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 406627 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30379568 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28802596 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 28802596 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 12680858 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 15147076 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19435959 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19435959 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17898698 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 17112804 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 17112804 — Biomarker: ABCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 17112804 — Biomarker: MRP2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ABCC2; DJS; cMRP
Study 17112804 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 28302271 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12906063 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12906063 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10562579 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 10562579 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 6351988 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 22944060 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22944060 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22944060 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20710084 — Biomarker: ABCD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCD1; ALD
Study 11915378 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 31788995 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31788995 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 31788995 — Biomarker: Homologous recombination deficiency
Type: Predictive Biomarker (PRD)
Study 23141780 — Biomarker: Carbonic anhydrase IX
Type: Predictive Biomarker (PRD)
Genes: CA9; G250; MN
Study 12745614 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 1329477 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22274951 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19099009 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9430449 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 31666688 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30354399 — Biomarker: IGFBP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP7; MAC25; PSF
Study 30354399 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 22931620 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22931620 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 17240625 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 17240625 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 17240625 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17240625 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17240625 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study 8861742 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8861742 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1703769 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 23356210 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 23356210 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 18196620 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12143454 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30285092 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20458441 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22708798 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 22708798 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 21698545 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10216089 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 28457318 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20647959 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16435613 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10588996 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 8948369 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9402176 — Biomarker: VHL mRNA
Type: Predictive Biomarker (PRD)
Genes: VHL
Study 9402176 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 9402176 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24996416 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16184439 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 12637464 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8931083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21364487 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23331844 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 21241828 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16042028 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 18278987 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 1714018 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20235087 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 16091636 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 26884344 — Biomarker: GAPDH mRNA
Type: Predictive Biomarker (PRD)
Genes: GAPDH; GAPD; CDABP0047; OK/SW-cl.12
Study 26884344 — Biomarker: ACTB mRNA
Type: Predictive Biomarker (PRD)
Genes: ACTB
Study 26884344 — Biomarker: RPLP0 mRNA
Type: Predictive Biomarker (PRD)
Genes: RPLP0
Study 26884344 — Biomarker: IGF1R mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1R
Study 26884344 — Biomarker: Amphiregulin
Type: Safety Biomarker (SAF)
Genes: AREG; AREGB; SDGF
Study 15136218 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8094114 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29373476 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 29373476 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 26395174 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8863236 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1321655 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3453169 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30169969 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 22851700 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18427418 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7562679 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7562679 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20552094 — Biomarker: CPE mRNA
Type: Predictive Biomarker (PRD)
Genes: CPE
Study 31610021 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25885668 — Biomarker: SRCIN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SRCIN1; KIAA1684; P140; SNIP
Study 30624952 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 30624952 — Biomarker: DOCK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DOCK3; KIAA0299; MOCA
Study 11504276 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 9737352 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 9737352 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9495218 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31842969 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 23871490 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 7990079 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30213849 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 8465360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20565454 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 2564834 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2564834 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16778712 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 9264477 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3040923 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 26525188 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17591031 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22159017 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 1455910 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 25039544 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21238825 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26366481 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 26366481 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 26366481 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26366481 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26366481 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 26366481 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17175305 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22571978 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 16268751 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6781157 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26955895 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26955895 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30716200 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 22453547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1526735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30108104 — Biomarker: miR-31
Type: Predictive Biomarker (PRD)
Genes: MIR31
Study 28836054 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 11672449 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 29804377 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 29804377 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23715641 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 17399814 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 24429320 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 23568851 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18492315 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14650580 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 23688265 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 10765004 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 27657477 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16603634 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 10423634 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21055143 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21055143 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 21055143 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1595849 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1457432 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 24623718 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24623718 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24623718 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 8611450 — Biomarker: CD52 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD52; CDW52; HE5
Study 2285631 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 26303352 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 26303352 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 19927630 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 15167457 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15167457 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31397488 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 26216500 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11032589 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22464408 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22464408 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8017639 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 8017639 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25932549 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9447850 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9447850 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7545256 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 7545256 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 25408222 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 20628825 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15644588 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 15644588 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15644588 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29066219 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22968743 — Biomarker: CALD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CALD1; CAD; CDM
Study 22968743 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18250616 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18250616 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16358997 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16358997 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30203750 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25246338 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 25246338 — Biomarker: FUT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FUT1; H; HSC
Study 25246338 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20102716 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17907108 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17907108 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17907108 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10194424 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study 17531001 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17531001 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 2838288 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 31705746 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 31705746 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28470591 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 21653691 — Biomarker: ACTB mRNA
Type: Predictive Biomarker (PRD)
Genes: ACTB
Study 21653691 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 12853380 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12853380 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12853380 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27121185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22513879 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 2678834 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 8971298 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31653510 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 31653510 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 11834876 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18323719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15569875 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 9388801 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7695927 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12217282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2652029 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 21584942 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29222227 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12475833 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 7921214 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 30625189 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26298226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26298226 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7899583 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)