AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 27224553 — Biomarker: WAP four-disulfide core domain protein 2
Type: Predictive Biomarker (PRD)
Genes: WFDC2; HE4; WAP5
Study 27227701 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27230813 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 27232186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27232579 — Biomarker: LOXL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LOXL2
Study 27232917 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27232917 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 27233802 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 27233802 — Biomarker: ABCG2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 27233802 — Biomarker: SLCO1B3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 27234335 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27235137 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 27235137 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 27235137 — Biomarker: NOTCH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOTCH1; TAN1
Study 27235137 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 27235137 — Biomarker: IL21
Type: Predictive Biomarker (PRD)
Genes: Za11; IL-21
Study 27236390 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27242521 — Biomarker: Beta-secretase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: BACE1; BACE; KIAA1149
Study 27244882 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 27245312 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 27245312 — Biomarker: 2-hydroxyglutarate
Type: Pharmacodynamic Biomarker (PDY)
Study 27245663 — Biomarker: AIP mRNA
Type: Predictive Biomarker (PRD)
Genes: AIP; XAP2
Study 27246604 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 27246604 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 27246911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27249553 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 27251684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27251684 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27253664 — Biomarker: AIP mRNA
Type: Predictive Biomarker (PRD)
Genes: AIP; XAP2
Study 27253664 — Biomarker: CUL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CUL1
Study 27255499 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 27255499 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 27255499 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 27255499 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 27255499 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 27255678 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 27257978 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 27258098 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27258647 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27260636 — Biomarker: TRPM8 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPM8; LTRPC6; TRPP8
Study 27260636 — Biomarker: TRPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPA1; ANKTM1
Study 27261237 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27262736 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 27262736 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27266507 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27266702 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27266721 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 27267549 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27267549 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27267942 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27268271 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 27269295 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27269940 — Biomarker: RTL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RTL1; MAR1; MART1; PEG11
Study 27269940 — Biomarker: IL21
Type: Predictive Biomarker (PRD)
Genes: Za11; IL-21
Study 27270177 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 27270177 — Biomarker: CARTPT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CARTPT; CART
Study 27270475 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 27271157 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 27276561 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 27276561 — Biomarker: IDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH2
Study 27281556 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27281556 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27281556 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27281556 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 27281773 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27281773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27281793 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 27282141 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27282141 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27282141 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 27282141 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27282998 — Biomarker: FCGR3A mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 27282998 — Biomarker: FCGR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR2A; CD32; FCG2; FCGR2A1; IGFR2
Study 27285281 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 27285295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27285295 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27285295 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27286790 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 27287231 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27287512 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27289552 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 27294305 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27294768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27296315 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 27296315 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 27296397 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27296397 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27296397 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 27297790 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27300170 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 27300170 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27300475 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 27300572 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 27300572 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27300572 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 27300572 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27302659 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 27307294 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 27307294 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 27307294 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 27309906 — Biomarker: RARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RARS1; RARS
Study 27312051 — Biomarker: SPAG5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPAG5
Study 27312804 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27313852 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27314177 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 27316444 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 27317257 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 27318133 — Biomarker: TSPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPO; BZRP; MBR
Study 27319305 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27325334 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 27325334 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 27325334 — Biomarker: XIST
Type: Predictive Biomarker (PRD)
Study 27325685 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27325685 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 27325856 — Biomarker: MLH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MLH1; COCA2
Study 27325856 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 27328699 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27329247 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 27329247 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27329447 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27330001 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 27330024 — Biomarker: FGG mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGG; PRO2061
Study 27330808 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 27330808 — Biomarker: MAGEA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAGEA3; MAGE3
Study 27330808 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27333947 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 27334557 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27334671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27335060 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27336786 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27336786 — Biomarker: ICOS mRNA
Type: Predictive Biomarker (PRD)
Genes: ICOS; AILIM
Study 27336786 — Biomarker: CXCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR5; BLR1; MDR15
Study 27338143 — Biomarker: TNF-related weak inducer of apoptosis
Type: Predictive Biomarker (PRD)
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study 27338143 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27338191 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 27340749 — Biomarker: SMPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMPD1; ASM
Study 27342580 — Biomarker: IGFBP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP7; MAC25; PSF
Study 27342748 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 27347680 — Biomarker: CCR2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCR2; CMKBR2
Study 27347680 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 27347680 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 27347680 — Biomarker: T-cell specific protein RANTES
Type: Safety Biomarker (SAF)
Genes: CCL5; D17S136E; SCYA5
Study 27350064 — Biomarker: CHEK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHEK1; CHK1
Study 27350064 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 27352953 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27354021 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 27354274 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27354477 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27354477 — Biomarker: Plasma DNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27354481 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 27355533 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 27355865 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 27355865 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 27356482 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27357090 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27357108 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 27357468 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 27357468 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27357840 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27358078 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27358088 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 27358088 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27358490 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 27369488 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 27371698 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 27371698 — Biomarker: PDGFRA mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 27371698 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 27374464 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 27374464 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 27375040 — Biomarker: RPE65 mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE65
Study 27376543 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27378554 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 27378554 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 27381904 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 27382096 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 27384242 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27384242 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 27384242 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27388672 — Biomarker: STAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT1
Study 27389402 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 27389402 — Biomarker: Neurofilament light polypeptide
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: NEFL; NF68; NFL
Study 27389402 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study 27390845 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27390845 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 27392483 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 27396777 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 27398025 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 27398025 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27400222 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27400814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27400896 — Biomarker: LMNA mRNA
Type: Predictive Biomarker (PRD)
Genes: LMNA; LMN1
Study 27400896 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27400898 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27402060 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 27402391 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 27402854 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 27402890 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 27403291 — Biomarker: PEPD mRNA
Type: Predictive Biomarker (PRD)
Genes: PEPD; PRD
Study 27403334 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27403996 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 27403996 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 27404941 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 27404941 — Biomarker: T-cell surface glycoprotein CD3 epsilon
Type: Predictive Biomarker (PRD)
Genes: CD3E; T3E
Study 27405442 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27405963 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27405963 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27406645 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27408945 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 27408945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27411053 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 27411053 — Biomarker: UBC mRNA
Type: Predictive Biomarker (PRD)
Genes: UBC
Study 27411053 — Biomarker: RPL30 mRNA
Type: Predictive Biomarker (PRD)
Genes: RPL30
Study 27411053 — Biomarker: RPL37A mRNA
Type: Predictive Biomarker (PRD)
Genes: RPL37A
Study 27411053 — Biomarker: RPLP0 mRNA
Type: Predictive Biomarker (PRD)
Genes: RPLP0
Study 27411053 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 27411053 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 27411053 — Biomarker: OAZ1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OAZ1; OAZ
Study 27411053 — Biomarker: DUSP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DUSP1; CL100; MKP1; PTPN10; VH1
Study 27411053 — Biomarker: Protein S100-P
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: S100P; S100E
Study 27411452 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27411452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27411683 — Biomarker: SPARC mRNA
Type: Predictive Biomarker (PRD)
Genes: SPARC; ON
Study 27412114 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27412386 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 27412526 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 27412889 — Biomarker: TNFRSF17 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF17; BCM; BCMA
Study 27413040 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27413040 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27414521 — Biomarker: TNXB mRNA
Type: Predictive Biomarker (PRD)
Genes: TNXB; HXBL; TNX; TNXB1; TNXB2; XB
Study 27415006 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27418050 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 27418632 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27418646 — Biomarker: CCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR4; CMKBR4
Study 27418929 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)