AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 17697915 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16141420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9772936 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9772936 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 7531877 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 7531877 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17594856 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17594856 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29511807 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 26370220 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20073227 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15269070 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 3078426 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 27018313 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23956183 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 21713704 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2067362 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 2067362 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29030065 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23785427 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 11672580 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26329656 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26329656 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26686682 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26686682 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24317556 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24317556 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24317556 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18602824 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11195715 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 27259714 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 7230728 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30411377 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10601178 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 8554931 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 28251402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18240879 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 16531896 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16531896 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10411250 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10411250 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 10411250 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 6990861 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22763465 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22763465 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 22763465 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22763465 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22790267 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 19446151 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15042010 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 12958723 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12958723 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 1990794 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31267524 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31267524 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28850021 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 20303788 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 14730323 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25738345 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 22571552 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 22571552 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22571552 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22571552 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18175550 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11533570 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11533570 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28125158 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 22046961 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11152850 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9539282 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 8088918 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8088918 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25982297 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 25982297 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 25982297 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27122490 — Biomarker: NOTCH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOTCH1; TAN1
Study 27122490 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27122490 — Biomarker: PGR mRNA
Type: Predictive Biomarker (PRD)
Genes: PGR; NR3C3
Study 27122490 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 27122490 — Biomarker: ACTA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACTA2; ACTSA; ACTVS; GIG46
Study 10835439 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 10835439 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8225149 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8225149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25509236 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25509236 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12812866 — Biomarker: Amyloid beta peptide (1-40)
Type: Pharmacodynamic Biomarker (PDY)
Genes: APP; A4; AD1
Study 12812866 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 10827410 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 10656954 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 10656954 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10656954 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 19846181 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 8137272 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 7014104 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18842788 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10487375 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 10487375 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10487375 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 16142748 — Biomarker: IL15 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL15
Study 16142748 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 16142748 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 10363725 — Biomarker: MINK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MINK1; B55; MAP4K6; MINK; YSK2; ZC3
Study 10363725 — Biomarker: TNFRSF25 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF25; APO3; DDR3; DR3; TNFRSF12; WSL; WSL1; UNQ455/PRO779
Study 10363725 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 2028004 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31014702 — Biomarker: ETV5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV5; ERM
Study 28415943 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23574969 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23574969 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9165176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31760132 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8664034 — Biomarker: TAOK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 6847424 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 19056555 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 11586485 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 913863 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26083701 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 29578578 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18360782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10051701 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 26365444 — Biomarker: FADS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS2
Study 8430713 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25006070 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 20552353 — Biomarker: Hydroxyphenylpyruvate dioxygenase
Type: Safety Biomarker (SAF)
Genes: HPD; PPD
Study 2884853 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21617527 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 21617527 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 18158312 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 14521738 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9407509 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9407509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1362778 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 1362778 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2862808 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 27497716 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 22045413 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17651149 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17651149 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 29943271 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29943271 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 29943271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28740376 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20955266 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 17240287 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 2112634 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 496555 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28698947 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 21882343 — Biomarker: PDCD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PDCD4; H731
Study 21882343 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21882343 — Biomarker: miR-21
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR21
Study 16113431 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9734729 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31722404 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31722404 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 31722404 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 28843241 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 28843241 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28843241 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25791025 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25791025 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25791025 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23795788 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 23795788 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 19001519 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 10904459 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22829267 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 18206738 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26786921 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 22040870 — Biomarker: PPARG mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARG; NR1C3
Study 22040870 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 22040870 — Biomarker: ADIPOQ mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 22040870 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 19169239 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 11345366 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11345366 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16125523 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12123399 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12123399 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12123399 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17317857 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 17317857 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 15159317 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 3895761 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30679315 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24659622 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 24659622 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24659622 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 10200837 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 314759 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 8980871 — Biomarker: GSS mRNA
Type: Predictive Biomarker (PRD)
Genes: GSS
Study 16790651 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22799766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26308174 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24050855 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19142758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 648737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21203888 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9493258 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28952798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16423119 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25423960 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 11755562 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29962032 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29962032 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 11208687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24528179 — Biomarker: RARA mRNA
Type: Predictive Biomarker (PRD)
Genes: RARA; NR1B1
Study 17123473 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 25992914 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19458107 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 19458107 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 11403509 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11403509 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18006539 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18006539 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10700598 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 31282129 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30100904 — Biomarker: PRCP mRNA
Type: Predictive Biomarker (PRD)
Genes: PRCP; PCP
Study 30100904 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 26879651 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 17598895 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21491012 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 12072872 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 10321438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29986745 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 27778191 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 17343981 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10021954 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27613946 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9649160 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 24835760 — Biomarker: TRIM63 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 24835760 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 20530281 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 28267900 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 15170918 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9663183 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27565841 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 1950542 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 23537492 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11177202 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9296413 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8400098 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF