AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT03786692 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03786692 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT03786692 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT01601028 — Biomarker: TLR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR7; UNQ248/PRO285
Study NCT01394042 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02552394 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00720304 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00573430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01918007 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01505621 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT01755442 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT01755442 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00741416 — Biomarker: CALD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CALD1; CAD; CDM
Study NCT04322773 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04322773 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT04322773 — Biomarker: Macrophage inflammatory protein 1-alpha
Type: Monitoring Biomarker (MOI)
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study NCT04322773 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT00520481 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT00102141 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01970696 — Biomarker: DICER1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DICER1; DICER; HERNA; KIAA0928
Study NCT00595998 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT00074997 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT04046848 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study NCT02163616 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00876187 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study NCT04437875 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT03525678 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study NCT03724487 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01243502 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study NCT02416531 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT02416531 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study NCT02416531 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study NCT00528203 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03745612 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02115373 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT04824560 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04024852 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05063318 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT04599933 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01256788 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT03890627 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study NCT03422315 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study NCT03258385 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT04130594 — Biomarker: Neutralizing antibody response
Type: Surrogate Endpoint (SUR)
Study NCT04130594 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT00696072 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00696072 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT03321695 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03321695 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT03321695 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT02384239 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study NCT02384239 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT01033175 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study NCT04799834 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885
Study NCT04116359 — Biomarker: BRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRD4; HUNK1
Study NCT00730067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00967746 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study NCT02851615 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03629535 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04390100 — Biomarker: FGG mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGG; PRO2061
Study NCT04390100 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT04003467 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03056092 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01942837 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study NCT02521532 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01848236 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00745680 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT01238172 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study NCT03357575 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT00464646 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00192309 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study NCT02501291 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03088280 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study NCT03038100 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02138630 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT02138630 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01261702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00872651 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01705171 — Biomarker: SLC2A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A5; GLUT5
Study NCT04317287 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03350685 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04008810 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study NCT04008810 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT00747851 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT01455688 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04186429 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT04186429 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT04051164 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT03187990 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00140738 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00935480 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study NCT00949546 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03956901 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT00267137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02970890 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04189068 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT04785131 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01023971 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03734796 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study NCT04135274 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study NCT00542269 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03546894 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT02926053 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT05518097 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study NCT02796170 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT02796170 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study NCT02796170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01753232 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03864107 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00732758 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study NCT03540303 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00402948 — Biomarker: CCR3 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CCR3; CMKBR3
Study NCT00402948 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00947336 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03906292 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT03906292 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT03514628 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02133599 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT02152852 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04414800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01553981 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT01553981 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study NCT01208714 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01394796 — Biomarker: DYRK1A mRNA
Type: Predictive Biomarker (PRD)
Genes: DYRK1A; DYRK; MNB; MNBH
Study NCT01424384 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study NCT04237805 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT04237805 — Biomarker: ROS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROS1; MCF3; ROS
Study NCT00926770 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04481191 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT03497624 — Biomarker: ROS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROS1; MCF3; ROS
Study NCT03125395 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study NCT03909789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01875653 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT04564287 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04018937 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01885767 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study NCT01885767 — Biomarker: NF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF2; SCH
Study NCT00389610 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00214370 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01499940 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study NCT02289950 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study NCT03198052 — Biomarker: GPC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPC3; OCI5
Study NCT03198052 — Biomarker: GUCY2C mRNA
Type: Predictive Biomarker (PRD)
Genes: GUCY2C; GUC2C; STAR
Study NCT03198052 — Biomarker: PSCA mRNA
Type: Predictive Biomarker (PRD)
Genes: PSCA; UNQ206/PRO232
Study NCT03198052 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03198052 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study NCT03198052 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03198052 — Biomarker: AXL mRNA
Type: Predictive Biomarker (PRD)
Genes: AXL; UFO
Study NCT03198052 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01352715 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study NCT02481674 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study NCT03850756 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study NCT00813670 — Biomarker: DNA repair endonuclease XPF
Type: Predictive Biomarker (PRD)
Genes: ERCC4; ERCC11; XPF
Study NCT03951675 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study NCT03944577 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study NCT03944577 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02830646 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study NCT00342797 — Biomarker: Retinoblastoma-associated protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: RB1
Study NCT02420821 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03919526 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT03919526 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study NCT03224429 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01941836 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00106912 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study NCT01186744 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study NCT02434848 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT02911844 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT00664833 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study NCT03711578 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study NCT06276829 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT04025853 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03524859 — Biomarker: CFTR
Type: Predictive Biomarker (PRD)
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study NCT04575389 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study NCT03718286 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study NCT03718286 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03708432 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03708432 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT03708432 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT00936208 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03490331 — Biomarker: COL17A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL17A1; BP180; BPAG2
Study NCT02651675 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study NCT02651675 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01605526 — Biomarker: MDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM2
Study NCT03332602 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT02875431 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study NCT02372474 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT03656289 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study NCT01477853 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01981343 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03729674 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01705600 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study NCT01705600 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study NCT00387504 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study NCT00921375 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT02168205 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study NCT00783783 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study NCT02275039 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study NCT00928408 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study NCT04594590 — Biomarker: SLC25A46 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A46; TB1
Study NCT03171220 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01761292 — Biomarker: LTBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: LTBP4
Study NCT00379652 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01323413 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00174187 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00063765 — Biomarker: CNTF mRNA
Type: Predictive Biomarker (PRD)
Genes: CNTF
Study NCT04489173 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02236520 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03173248 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study NCT02023463 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT00580814 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study NCT02081534 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03834961 — Biomarker: Tropomyosin-related kinase A
Type: Pharmacodynamic Biomarker (PDY)
Genes: NTRK1; MTC; TRK; TRKA
Study NCT04454853 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study NCT02124382 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study NCT00939874 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00330174 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study NCT01734213 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00323440 — Biomarker: MEFV mRNA
Type: Predictive Biomarker (PRD)
Genes: MEFV; MEF; TRIM20
Study NCT01896869 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00940082 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00940082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00940082 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01928355 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00633295 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT00633295 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study NCT03080766 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study NCT03888664 — Biomarker: Mitochondrial frataxin
Type: Monitoring Biomarker (MOI)
Genes: FXN; FRDA; X25
Study NCT03888664 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT03694444 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study NCT01677533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01486927 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study NCT04075721 — Biomarker: PSMB8 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSMB8; LMP7; PSMB5i; RING10; Y2
Study NCT03384615 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH