AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 25122150 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 11707563 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19344226 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 15601638 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25966138 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25966138 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7950469 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30549271 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30549271 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 30549271 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 30549271 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30549271 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 30549271 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23843375 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9893589 — Biomarker: KCNMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNMA1; KCNMA; SLO
Study 8594942 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 8594942 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10634176 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 27980008 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 4085468 — Biomarker: IRS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRS2
Study 29997249 — Biomarker: CRTC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CRTC1; KIAA0616; MECT1; TORC1; WAMTP1
Study 30450637 — Biomarker: SLC52A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC52A2; GPR172A; PAR1; RFT3
Study 19116919 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11212971 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25011982 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 25011982 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 25011982 — Biomarker: CYP17A1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CYP17A1; CYP17; S17AH
Study 25011982 — Biomarker: CYP19A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 11313303 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9141002 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 3343933 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 28633089 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 26297704 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26297704 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12883662 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 12372124 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 12372124 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 10449884 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28797783 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 28797783 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 26694073 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8776210 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 1730080 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 6085363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25238062 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 14694177 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 14694177 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30739519 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25407559 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 24267123 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 19711612 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 30646209 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30646209 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28449631 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28449631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21084567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15325680 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9564804 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 25716880 — Biomarker: SPART mRNA
Type: Predictive Biomarker (PRD)
Genes: SPART; KIAA0610; SPG20; TAHCCP1
Study 19967581 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 16645152 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 16645152 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30116124 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 22202972 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16296572 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2223342 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 30935866 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 22226275 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 19687024 — Biomarker: ALKBH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALKBH1; ABH; ABH1; ALKBH
Study 17596064 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 23925396 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 23925396 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 19309415 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 13129740 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12186343 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 10568044 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8923571 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2009366 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 7171417 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31348298 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 30477832 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20226040 — Biomarker: AKAP11 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKAP11; AKAP220; KIAA0629
Study 20226040 — Biomarker: BMPR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BMPR2; PPH1
Study 20226040 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 25012183 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 20877394 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20877394 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1637767 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 20443719 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 20443719 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17355218 — Biomarker: MTLN mRNA
Type: Predictive Biomarker (PRD)
Genes: MTLN; LEMP; LINC00116; MOXI; MPM; NCRNA00116; SMIM37
Study 16287371 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 2260727 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15897799 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12201833 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 12201833 — Biomarker: IGFBP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP2; BP2; IBP2
Study 2540786 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21745357 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 8095854 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 3094207 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22183484 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 411668 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 411668 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1713930 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 31358336 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 30530975 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 27339779 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12033702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1976051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29150250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19084088 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 9342579 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2878607 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17925589 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 11702012 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8988921 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8988921 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24716215 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 20864862 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 1292337 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 1292337 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 29954931 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25847557 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22615029 — Biomarker: PPP1R13L mRNA
Type: Predictive Biomarker (PRD)
Genes: PPP1R13L; IASPP; NKIP1; PPP1R13BL; RAI
Study 9377132 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 3297468 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31912695 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 31912695 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 16258165 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 16258165 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21215143 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20415152 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 17938383 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17938383 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 15739120 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 3049876 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 27612501 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16861942 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22474419 — Biomarker: PDGFRB
Type: Predictive Biomarker (PRD)
Genes: JTK12; CD140b; PDGFR1
Study 17634484 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 30664816 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25421981 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25421981 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23171375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7952357 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 27254034 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 17891480 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16025736 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16025736 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 10423597 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10423597 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3665737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30043749 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 30043749 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 20339969 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20339969 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 30706792 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30706792 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26014294 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22013796 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17284923 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11900820 — Biomarker: Auditory mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 11900820 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 28052977 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21546102 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 21546102 — Biomarker: MEA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MEA1; MEA
Study 26565690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17570262 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 8665540 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27236884 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27236884 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24872682 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 11978287 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29357894 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23037612 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 21235330 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19207276 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 7975357 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7975357 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17848650 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9355669 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23963046 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15785088 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 10716202 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 2220013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25938681 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 31425456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30040140 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25322607 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17593932 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16720676 — Biomarker: SNAP25 mRNA
Type: Predictive Biomarker (PRD)
Genes: SNAP25; SNAP
Study 16720676 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 10470219 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 21084767 — Biomarker: SLC15A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC15A2; PEPT2
Study 22697581 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 17178264 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17178264 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 17178264 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12812863 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 29506460 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 18981503 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 1145988 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31385202 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31385202 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 27217412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20040338 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 20040338 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 20040338 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 17976224 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 3147477 — Biomarker: CPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPZ
Study 21157106 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21157106 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19118120 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15166558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28450350 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28450350 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3912621 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30954261 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30954261 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 30954261 — Biomarker: KIT
Type: Predictive Biomarker (PRD)
Genes: CD117; SCFR; C-Kit
Study 30954261 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24300266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15734615 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12899316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1723378 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 28526225 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 17317931 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11193249 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3887847 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20071701 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 20071701 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7594088 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1988576 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 23856660 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 23856660 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 17513706 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 17513706 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 17513706 — Biomarker: Insulin receptor substrate 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IRS1
Study 11427221 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11427221 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11427221 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 11427221 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 9732339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9732339 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22773551 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 26968644 — Biomarker: INPP5D mRNA
Type: Predictive Biomarker (PRD)
Genes: INPP5D; SHIP; SHIP1
Study 20087332 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES