AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT02352974 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study NCT03887182 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study NCT03407196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00171405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04263220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03499626 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study NCT03499626 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03499626 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03499626 — Biomarker: ERBB4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB4; HER4
Study NCT03093441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03437538 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study NCT04571814 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00252915 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01204580 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03159156 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02206659 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01910857 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03052491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01835678 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT02383511 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study NCT00442234 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT00934089 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00799383 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03677921 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT04682041 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885
Study NCT04682041 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT04682041 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT00265759 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT02602314 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT02602314 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT03649893 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02235025 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT02576002 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT00004067 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00320788 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00959283 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study NCT00347542 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00347542 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04326777 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study NCT01443065 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01443065 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00189982 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study NCT04324255 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study NCT04324255 — Biomarker: ADAMTS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT04324255 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study NCT04185311 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04185311 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT03066830 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00003805 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT02070744 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study NCT04121026 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04314349 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04549636 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT04568044 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT03857893 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study NCT04944251 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study NCT00204230 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00925249 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04447651 — Biomarker: U2AF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: U2AF1; U2AF35; U2AFBP; FP793
Study NCT02098967 — Biomarker: MDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM2
Study NCT03048734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01249664 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03131908 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study NCT03131908 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study NCT02509273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00791570 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT00791570 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study NCT00791570 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT03187275 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT01423201 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT04069715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02197247 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT02197247 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02197247 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT01819298 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study NCT05946148 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT02476526 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT00962676 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT01940601 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study NCT01202812 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT05517915 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04425512 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT02191683 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02191683 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT00633750 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00633750 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT01471678 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00105417 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT03773263 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02728596 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT02728596 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT04036019 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT04036019 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT01018563 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study NCT02210767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03482544 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT03320174 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study NCT00844129 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study NCT00626223 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02258464 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02258464 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT02258464 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03082781 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03082781 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00932646 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT05206578 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study NCT01096381 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00636558 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study NCT03765632 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT03765632 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study NCT03765632 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study NCT03128411 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT02030184 — Biomarker: SSTR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SSTR2
Study NCT00384566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03717259 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT03179657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03179657 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01969357 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT02499822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04499339 — Biomarker: SLAMF7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLAMF7; CS1; UNQ576/PRO1138
Study NCT02738593 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02738593 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00237094 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00001872 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT02578511 — Biomarker: POMP mRNA
Type: Predictive Biomarker (PRD)
Genes: POMP; C13orf12; UMP1; HSPC014; HSPC036; PNAS-110
Study NCT04217720 — Biomarker: ASPH mRNA
Type: Predictive Biomarker (PRD)
Genes: ASPH; BAH
Study NCT03164135 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study NCT03164135 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT04769804 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study NCT02379156 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04755543 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01275885 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03663998 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study NCT01794117 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study NCT01795794 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT02959723 — Biomarker: BMPR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BMPR2; PPH1
Study NCT04888468 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT00008203 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT00008203 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT00402415 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03130257 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03148132 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03148132 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT00899574 — Biomarker: TLR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR7; UNQ248/PRO285
Study NCT02733432 — Biomarker: CD101 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD101; EWI101; IGSF2; V7
Study NCT04380896 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT00195715 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03673852 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01921387 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study NCT01018706 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study NCT01151007 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT02155985 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT01096082 — Biomarker: Ataxin-3
Type: Pharmacodynamic Biomarker (PDY)
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study NCT01096082 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT01124669 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT01124669 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03113110 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT03113110 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01625026 — Biomarker: NR1H4 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT04726800 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study NCT00172757 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study NCT00172757 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study NCT00172757 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study NCT01744925 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01744925 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03027687 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02019693 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT02019693 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02019693 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study NCT02019693 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT03758066 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT01734187 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01734187 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01734187 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02338076 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study NCT00237549 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00678509 — Biomarker: TTK mRNA
Type: Predictive Biomarker (PRD)
Genes: TTK; MPS1; MPS1L1
Study NCT00678509 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT04876378 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT02739594 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT00786890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00514046 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT00514046 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study NCT04407221 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT01456481 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03225846 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study NCT02369042 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT02908360 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00796822 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT06611904 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT01878370 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00638599 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00148915 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01302756 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT03675477 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study NCT03675477 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study NCT00249756 — Biomarker: MHC class I polypeptide-related sequence A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MICA; PERB11.1
Study NCT02855164 — Biomarker: NR1H4 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT03135704 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study NCT00238810 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study NCT00493025 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04454294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00001849 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00005378 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01695109 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT03416192 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study NCT03416192 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study NCT01461733 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00342056 — Biomarker: ABCG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study NCT04114695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04071600 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study NCT01462214 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT01462214 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study NCT03084939 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04282590 — Biomarker: Tropomyosin-related kinase A
Type: Pharmacodynamic Biomarker (PDY)
Genes: NTRK1; MTC; TRK; TRKA
Study NCT04367662 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT01234766 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study NCT03918954 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01613261 — Biomarker: Aurora kinase A
Type: Predictive Biomarker (PRD)
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT00634907 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study NCT00634907 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study NCT02192736 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT00269048 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT03095612 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT02984111 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study NCT00405171 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00330512 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)