AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 29490310 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24472084 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 17907112 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28887690 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 28887690 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 21456017 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30694011 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29044764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25116230 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19761536 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15990127 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7821124 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 26476943 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 23775260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22841432 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8684686 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1904892 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 29171848 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29171848 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 16636540 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 12559795 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8987040 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8427660 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30665819 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24856575 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21199306 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 11854123 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11898768 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 10211862 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10211862 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 10211862 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 27273879 — Biomarker: PI3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PI3; WAP3; WFDC14
Study 7892259 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 7892259 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31469710 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27584910 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 27584910 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 19075260 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9413962 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9413962 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29635492 — Biomarker: RBM46 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBM46
Study 29635492 — Biomarker: PEG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PEG3; KIAA0287; ZSCAN24
Study 29635492 — Biomarker: IGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF2; PP1446
Study 29635492 — Biomarker: GRB10 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRB10; GRBIR; KIAA0207
Study 29635492 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 29635492 — Biomarker: GRIN3B mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIN3B
Study 29635492 — Biomarker: OPCML mRNA
Type: Predictive Biomarker (PRD)
Genes: OPCML; IGLON1; OBCAM
Study 29635492 — Biomarker: Apolipoprotein C-II
Type: Monitoring Biomarker (MOI)
Genes: APOC2; APC2
Study 18729811 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12535810 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10232562 — Biomarker: Glutamate dehydrogenase
Type: Safety Biomarker (SAF)
Study 8553333 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24372302 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 22622108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29178891 — Biomarker: SHC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SHC1; SHC; SHCA
Study 3158243 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22769423 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 9358963 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7685452 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 29764793 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 29764793 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 29764793 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 25867538 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1465288 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 25022107 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 19884549 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 19884549 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19884549 — Biomarker: MLH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MLH1; COCA2
Study 18326980 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18326980 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8758853 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28578639 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 17201848 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 1890860 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31936767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24114668 — Biomarker: Amphiregulin
Type: Safety Biomarker (SAF)
Genes: AREG; AREGB; SDGF
Study 16938913 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23318050 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 18753745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17081355 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14692654 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 14692654 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 14692654 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 29495655 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 21311362 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15954914 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 11602855 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22017520 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 20537751 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26013003 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26013003 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26013003 — Biomarker: Interleukin 1 alpha
Type: Safety Biomarker (SAF)
Genes: IL1A; IL1F1
Study 26013003 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 26013003 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16969009 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 14748820 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24986773 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22621684 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22621684 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31754048 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 26175059 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study 26175059 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22966789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15190802 — Biomarker: ZP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZP3; ZP3A; ZP3B; ZPC
Study 11309009 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 31411975 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 8915402 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8915402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24975596 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 18467543 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 10451911 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 15166654 — Biomarker: Plasma testosterone level
Type: Surrogate Endpoint (SUR)
Study 15166654 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9832603 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 396111 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28112533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19925617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31096941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23398953 — Biomarker: FCGR2B
Type: Predictive Biomarker (PRD)
Genes: CD32; CD32B; FcgammaRIIb; FcGRIIB
Study 23398953 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 17142146 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17142146 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12663600 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 10873879 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25901734 — Biomarker: ITGA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGA2; CD49B
Study 25901734 — Biomarker: F2R mRNA
Type: Predictive Biomarker (PRD)
Genes: F2R; CF2R; PAR1; TR
Study 25901734 — Biomarker: P2RY12 mRNA
Type: Predictive Biomarker (PRD)
Genes: P2RY12; HORK3
Study 24189254 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 16331754 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23302662 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6387210 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30139835 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 26333375 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 1424027 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 22870185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7737713 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6248010 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24088993 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 21958068 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8985103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1728157 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 25319597 — Biomarker: BCAR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCAR1; CAS; CASS1; CRKAS
Study 23243245 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 21308291 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 14564686 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11697754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16776681 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 27109816 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 22215473 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7572689 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10848048 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10525558 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8675251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20021458 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 12562110 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 786670 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 29308523 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29308523 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 29308523 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29308523 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 23668634 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 17766923 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30372126 — Biomarker: OPRM1
Type: Safety Biomarker (SAF)
Genes: MOR1; MOP
Study 29699021 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 26873242 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24444545 — Biomarker: EEF1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EEF1A2; EEF1AL; STN
Study 17785618 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 15932791 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 9616263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30222051 — Biomarker: REG1A mRNA
Type: Predictive Biomarker (PRD)
Genes: REG1A; PSPS; PSPS1; REG
Study 20471706 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19480865 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 28532406 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 28532406 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27128001 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 21146637 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 30586694 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 30586694 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 28765326 — Biomarker: CDKN2A mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2A; CDKN2; MTS1
Study 28765326 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 28765326 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 26621626 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8553906 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7058754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11804663 — Biomarker: CYP2E1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2E1; CYP2E
Study 7190495 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23547240 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7967349 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 26129694 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 19819688 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24023786 — Biomarker: FNDC5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FNDC5; FRCP2
Study 24023786 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 19002384 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 19002384 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19002384 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 11740820 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 11740820 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11029398 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 11029398 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 3543234 — Biomarker: Tropomyosin-related kinase A
Type: Pharmacodynamic Biomarker (PDY)
Genes: NTRK1; MTC; TRK; TRKA
Study 26042037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23816723 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23816723 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23816723 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23816723 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22137686 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22137686 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 24008122 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20036363 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31738228 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 31738228 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 31738228 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 31738228 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 31738228 — Biomarker: HTR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2A; HTR2
Study 28160545 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 28160545 — Biomarker: SQSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SQSTM1; ORCA; OSIL
Study 26162657 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 18405442 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18405442 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10101926 — Biomarker: MAX mRNA
Type: Predictive Biomarker (PRD)
Genes: MAX; BHLHD4
Study 10101926 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 15957833 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 7669306 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2160490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 433814 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29961138 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 29961138 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 21646287 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 21646287 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 11906445 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9477042 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28628003 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 18926439 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16735174 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10466240 — Biomarker: TICAM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TICAM2; TIRAP3; TIRP; TRAM
Study 8626878 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 120078 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11320586 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 11320586 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 8971305 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 2996310 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24991045 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD