AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 3011834 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17694505 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 30844812 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study 20228401 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17355281 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 2240675 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2240675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10548198 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 22857721 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 25029806 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 17721997 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 9661596 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12359676 — Biomarker: NE
Type: Predictive Biomarker (PRD)
Study 27457818 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 20413040 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20413040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11286371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8803961 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3892676 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30344180 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31841795 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 31841795 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12392588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18308753 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 1833682 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1833682 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25225000 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 23249810 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 16136646 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 31809985 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31809985 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31809985 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 18543100 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16440357 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 8421182 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8421182 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 24989060 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24989060 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 10229311 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 6574528 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 30371190 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23357715 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 1101614 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15995958 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 15995958 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27225334 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17587389 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17587389 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7547368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7284971 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 30740695 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 15897583 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 8452271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15716665 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25854593 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 25854593 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 23723410 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study 23723410 — Biomarker: ROPN1L mRNA
Type: Predictive Biomarker (PRD)
Genes: ROPN1L; ASP; RSPH11
Study 19562253 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19562253 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 17415706 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 25413896 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21353463 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 15497369 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 22000423 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 19324483 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 16964676 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 1570887 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29948863 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24505249 — Biomarker: CCN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 24505249 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24505249 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8119688 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 1092516 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 27706121 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 31787369 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27832260 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27832260 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 23595134 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 16824986 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 12624284 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 12624284 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 2943594 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25366952 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17641591 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 14503056 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 9346990 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 23803593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22463944 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18953177 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 18953177 — Biomarker: SERPINA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 18953177 — Biomarker: Vitamin K-dependent protein C
Type: Safety Biomarker (SAF)
Genes: PROC
Study 18953177 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 18953177 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 1997518 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31446992 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 26844688 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26844688 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 1641292 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 1641292 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 26316741 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 6310996 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24888488 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20530973 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 18613793 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18613793 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16485513 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8949568 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31072023 — Biomarker: NOCT mRNA
Type: Predictive Biomarker (PRD)
Genes: NOCT; CCR4; CCRN4L; NOC
Study 25710276 — Biomarker: BAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAK1; BAK; BCL2L7; CDN1
Study 21570522 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21570522 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17623345 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15580811 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7989939 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 28314744 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 22959395 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 21982664 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 21982664 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21982664 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12709465 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 12709465 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12709465 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3003298 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 3003298 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3003298 — Biomarker: ABCD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCD1; ALD
Study 3003298 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31510831 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31510831 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24317794 — Biomarker: PPARGC1A mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1
Study 24317794 — Biomarker: PPARGC1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARGC1B; PERC; PGC1; PGC1B; PPARGC1
Study 30785496 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 29392288 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25731901 — Biomarker: Glutamate dehydrogenase
Type: Safety Biomarker (SAF)
Study 21058473 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17558118 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2291868 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31112385 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 24447181 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 15636619 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 25733246 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16508637 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 11095480 — Biomarker: STK11 mRNA
Type: Predictive Biomarker (PRD)
Genes: STK11; LKB1; PJS
Study 28634217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21350366 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18637980 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15569067 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 23664208 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23664208 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1280735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30366815 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 30366815 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 27132170 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 21082868 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 21082868 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21082868 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11431944 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 22840421 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 15877873 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24488610 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 10839333 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 24470557 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24470557 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 24470557 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 15507508 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1518261 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 30557128 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18647851 — Biomarker: MMP13 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP13
Study 26429571 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 11686867 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 9197292 — Biomarker: Alpha-glutathione S-transferase
Type: Safety Biomarker (SAF)
Study 9197292 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19427680 — Biomarker: ADAMTS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 31778439 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 11686808 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 28825891 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 15725986 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10376694 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 10376694 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 30938809 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 11471515 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30553555 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9404441 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 9404441 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3126455 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24060588 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 12812689 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10565607 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 6110188 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31047819 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 25723140 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15202047 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 26892413 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 17400977 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17400977 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17400977 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 17400977 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 30619887 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 10391070 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 10391070 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20104935 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17604563 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7999408 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 31040088 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22250032 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22250032 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24993458 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24993458 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28860019 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 28860019 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17409767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17409767 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21502567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18931204 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18931204 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 18931204 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 18931204 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12826159 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 7067470 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7067470 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 24569459 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24569459 — Biomarker: PHEX mRNA
Type: Predictive Biomarker (PRD)
Genes: PHEX; PEX
Study 25831464 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25831464 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21094951 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 14985229 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 14985229 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19398603 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 3501274 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 8607936 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28137517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7595182 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 7595182 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 7595182 — Biomarker: PLTP mRNA
Type: Predictive Biomarker (PRD)
Genes: PLTP
Study 7595182 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 11517739 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11517739 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 30980923 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10