AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 21149931 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9605674 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7908864 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 10878692 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10878692 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10878692 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 19175893 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28963591 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 12756602 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12756602 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10566921 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1845926 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31828274 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 25138171 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17295721 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10803937 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 3533562 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31255349 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study 27720066 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20185740 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20185740 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 6751705 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6751705 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28328713 — Biomarker: GAL3ST1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAL3ST1; CST
Study 23057323 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 17698897 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12361192 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12361192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6995617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23646470 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17844693 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18195316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12440177 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28625806 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 25875387 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 14517708 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 11063909 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28832630 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28832630 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28832630 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28832630 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 28832630 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 28832630 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25879343 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 23290547 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21088675 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21088675 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 21088675 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21088675 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 19720764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11161394 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9788689 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 31900997 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17006839 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 9085509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1676891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10682152 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1888046 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30236042 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 18834244 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 8912502 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 7705006 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26031901 — Biomarker: GLT1D1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLT1D1
Study 20217115 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 20217115 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 20217115 — Biomarker: TBC1D4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TBC1D4; AS160; KIAA0603
Study 18387391 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 18387391 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7840730 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28249084 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 23746666 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 11473855 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19596188 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18333866 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 23564205 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12047397 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 12047397 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 31728681 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31728681 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 18565968 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18565968 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18565968 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1590574 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19628211 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 12740676 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16129365 — Biomarker: MYCN mRNA
Type: Predictive Biomarker (PRD)
Genes: MYCN; BHLHE37; NMYC
Study 8778905 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26011816 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26011816 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 26011816 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 22260834 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10468801 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10468801 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30359763 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23958473 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 21030684 — Biomarker: GLS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS2; GA
Study 1761364 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27153942 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 15886446 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15886446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 416763 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22035131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17956153 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17956153 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10350494 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 7851558 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 29653550 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28199752 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 28199752 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28199752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26233509 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26233509 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26233509 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 15323062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27528062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25483635 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 15795438 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12846271 — Biomarker: CYP19A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 12846271 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10975887 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3915317 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17898990 — Biomarker: PPARG mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARG; NR1C3
Study 11567990 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 7880511 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28586262 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23262750 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 16196417 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16196417 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 16196417 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 9542208 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 326593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10099655 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31557380 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 29519921 — Biomarker: ELK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELK3; NET; SAP2
Study 26346638 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24940656 — Biomarker: ZMYM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZMYM2; FIM; RAMP; ZNF198
Study 12389594 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 9649908 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 9649908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26783978 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 17928803 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11304505 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11304505 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 9282547 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 8512659 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3805544 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 31053954 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 31053954 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 31053954 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24510471 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 21261107 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11243072 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 30382270 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18227370 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18227370 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24801367 — Biomarker: TMPRSS6 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMPRSS6; UNQ354/PRO618
Study 7494611 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7494611 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 552657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27591988 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 27591988 — Biomarker: Cytokine ML-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IL17F
Study 15983290 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12270981 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12270981 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 10097934 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10097934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8947977 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31615021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22435835 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22435835 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17884359 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8950071 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 8950071 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28316174 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24379072 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 14747225 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31013550 — Biomarker: Fatty acid amide hydrolase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: FAAH; FAAH1
Study 31013550 — Biomarker: CNR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNR1; CNR
Study 26450601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26450601 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 19348600 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11565669 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3074299 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26725385 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31329901 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 31329901 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24604886 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 15865226 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9651635 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 31103412 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31103412 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 3089467 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 15916998 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15916998 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 15916998 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29932518 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 19915736 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 6528617 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31377477 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31377477 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19833273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10595814 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 10595814 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29094998 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 21906521 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 21906521 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 17584010 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 16139813 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 3890049 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22686944 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7618647 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 30214066 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 19960001 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 19960001 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 28697780 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16222900 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16222900 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25942482 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 21505361 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19740297 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 16782975 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8833208 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26024293 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 17668564 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15189781 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15189781 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11349017 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 31873788 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29664983 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29664983 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19082803 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19082803 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10862636 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2862223 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 27146650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15936184 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9094892 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3541168 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30134847 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 27780198 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 24285284 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 10430720 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 6381007 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24709780 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24709780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22450429 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19