AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 8391756 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26571012 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27929530 — Biomarker: DCC mRNA
Type: Predictive Biomarker (PRD)
Genes: DCC; IGDCC1
Study 18719760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24026142 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24026142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8571194 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6886033 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31797473 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 31797473 — Biomarker: OLR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OLR1; CLEC8A; LOX1
Study 31797473 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 31797473 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 27693003 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 27693003 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 27693003 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 27693003 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 23113833 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 23113833 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18845960 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 18845960 — Biomarker: CCR2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCR2; CMKBR2
Study 18845960 — Biomarker: CX3CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CX3CR1; CMKBRL1; GPR13
Study 18845960 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 12621013 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 1462984 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30640988 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 30371759 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29846606 — Biomarker: MAX mRNA
Type: Predictive Biomarker (PRD)
Genes: MAX; BHLHD4
Study 3307307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27029960 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25564396 — Biomarker: RHD mRNA
Type: Predictive Biomarker (PRD)
Genes: RHD
Study 25739904 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24517060 — Biomarker: Urinary total protein
Type: Safety Biomarker (SAF)
Study 16963658 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 3654034 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 31724349 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22101876 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22101876 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9631802 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7874838 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31366977 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 25948208 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 25948208 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25948208 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17069814 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28382618 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23647281 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 16482646 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16948927 — Biomarker: CARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARS1; CARS
Study 16948927 — Biomarker: CGAS mRNA
Type: Predictive Biomarker (PRD)
Genes: CGAS; C6orf150; MB21D1
Study 14503797 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 10895224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28432157 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28432157 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 28432157 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 20690864 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15315625 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 9076589 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30478089 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 22334769 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 26659384 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25149384 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23129602 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 23129602 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6374931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28046032 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 28046032 — Biomarker: SMPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMPD1; ASM
Study 23469685 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 23469685 — Biomarker: ABCG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 23469685 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 23469685 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 23469685 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 10912746 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22699418 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 22699418 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 9988803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17926612 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15178812 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15178812 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20446945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21392096 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21392096 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15126524 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 26252751 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 20886231 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 9088654 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11044464 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 24423366 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23301470 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 23301470 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 7529522 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 7529522 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 727423 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26525549 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 26525549 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26525549 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 24225205 — Biomarker: NR4A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR4A1; GFRP1; HMR; NAK1
Study 10790574 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 7755939 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26158441 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 26158441 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 26158441 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 9314427 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3524465 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 3524465 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 20675691 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 20675691 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 20675691 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 15761945 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22187590 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 29474712 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 29474712 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24229565 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 20131262 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 18467621 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 21306829 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17578485 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17578485 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 14969424 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 31852916 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31852916 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15817850 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 12613519 — Biomarker: ESD mRNA
Type: Predictive Biomarker (PRD)
Genes: ESD
Study 12613519 — Biomarker: UBR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: UBR5; EDD; EDD1; HYD; KIAA0896
Study 9750444 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 7625419 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2778913 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31805256 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 20007431 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20007431 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20007431 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 20007431 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 20007431 — Biomarker: C-X-C motif chemokine 11
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 20007431 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC
Study 20007431 — Biomarker: CCL22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 20007431 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 17622279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15908667 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 484753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30979559 — Biomarker: AXL mRNA
Type: Predictive Biomarker (PRD)
Genes: AXL; UFO
Study 25170012 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 22669546 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11779724 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 21055142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21055142 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 12886670 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1336516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29537447 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 18559703 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 26310261 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26310261 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 26310261 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 19685943 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 6861846 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20169359 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 20169359 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 16393332 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10385012 — Biomarker: NSMAF mRNA
Type: Predictive Biomarker (PRD)
Genes: NSMAF; FAN
Study 16160131 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 2355103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2355103 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30927200 — Biomarker: CA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA4
Study 8754956 — Biomarker: CEACAM6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CEACAM6; NCA
Study 27157472 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8702053 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 8702053 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1687130 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 1687130 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10559514 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17804334 — Biomarker: ZP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZP3; ZP3A; ZP3B; ZPC
Study 16035374 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 332218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31494015 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 28344197 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19808130 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 19808130 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11711507 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29354988 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 23595153 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21166598 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18359215 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 26985905 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10703776 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8963728 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24824197 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 10487502 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8598593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29121975 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25557658 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31486833 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31486833 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 22252217 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 12915604 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 10485635 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 6653642 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30637907 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29683755 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 27687887 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18769356 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7428802 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 28586162 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 10660238 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8346818 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2871945 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 25511185 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 25511185 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 21046232 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 7933491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2851177 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 23064980 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15876900 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 1578946 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31478290 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19246733 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17122621 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10505743 — Biomarker: IFNAR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNAR1; IFNAR
Study 8726600 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12484804 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1909810 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 6666842 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 20880345 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20880345 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20880345 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8746601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28560832 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 10780760 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26276501 — Biomarker: HDC mRNA
Type: Predictive Biomarker (PRD)
Genes: HDC
Study 26276501 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 21442611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16962881 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25205142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8507417 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24403477 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8487326 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3031714 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22387758 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 18217157 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 18217157 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 10811451 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study 1808368 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25691036 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 25691036 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 7989637 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 21870174 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23046525 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 23046525 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16164451 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 15848504 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL