AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 25863779 — Biomarker: MMP13 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP13
Study 25863779 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 23211475 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 23211475 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 23211475 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21255472 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 15798546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1631878 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24614605 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24614605 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24614605 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24614605 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 25298575 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21134821 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12578781 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10547209 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 1801688 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30842213 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 17507365 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 17507365 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16327033 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 282084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23332366 — Biomarker: NEB mRNA
Type: Predictive Biomarker (PRD)
Genes: NEB
Study 19498438 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19498438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17201277 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1775603 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10220835 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 10220835 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 7604787 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7604787 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31503048 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23758736 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 20053471 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20053471 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 20053471 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 30183583 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 30183583 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9504817 — Biomarker: HSP90B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSP90B1; GRP94; TRA1
Study 9504817 — Biomarker: HSPA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA5; GRP78
Study 9504817 — Biomarker: HSPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPD1; HSP60
Study 9504817 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 3786603 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19713950 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18652113 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15975300 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 1406078 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3902912 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27846344 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 27846344 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20820916 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 20820916 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 18549466 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18549466 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 11292011 — Biomarker: DMTN mRNA
Type: Predictive Biomarker (PRD)
Genes: DMTN; DMT; EPB49
Study 11292011 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3221745 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3221745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22642937 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 2645120 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6769666 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 11793634 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 799561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31483155 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15238773 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15238773 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8363210 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3534801 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3534801 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30890817 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30890817 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10423078 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2580164 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2580164 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30827252 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23128163 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 23128163 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16632842 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26224543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22658688 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 22658688 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 12732880 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 12732880 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 10199772 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 1723456 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1723456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22431131 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11999569 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 24993098 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11788225 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7211734 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7211734 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7211734 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 31983312 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25828601 — Biomarker: SLBP mRNA
Type: Predictive Biomarker (PRD)
Genes: SLBP; HBP
Study 19280831 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 2551204 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28614905 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 19298202 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19298202 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19298202 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11276502 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 29104121 — Biomarker: ISG15 mRNA
Type: Predictive Biomarker (PRD)
Genes: ISG15; G1P2; UCRP
Study 19807952 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9284852 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 1329673 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 1329673 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 31605792 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 30442122 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26369526 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 24481719 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24481719 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 2732023 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10852983 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28986703 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12633543 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10687671 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3299394 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12865480 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 17218573 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 21701528 — Biomarker: ARHGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARHGEF5; TIM
Study 19433694 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16675323 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 16124647 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 30778667 — Biomarker: KLK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLK3; APS
Study 29395188 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 27872863 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 24136652 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 12425849 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31227872 — Biomarker: ARID5B mRNA
Type: Predictive Biomarker (PRD)
Genes: ARID5B; DESRT; MRF2
Study 19770393 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17324738 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24120216 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 14555558 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 26257209 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 9796636 — Biomarker: SLC25A21 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A21; ODC
Study 24477618 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15992517 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15992517 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31154309 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22179079 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17693888 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 17693888 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 15177064 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 7597693 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 23570863 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 17881750 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12548591 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 12548591 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study 12548591 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8780281 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1293241 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 31014399 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15014007 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 27656054 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 27656054 — Biomarker: MAF mRNA
Type: Predictive Biomarker (PRD)
Genes: MAF
Study 22747899 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 14582037 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22529265 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 18480825 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1337459 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1337459 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29772111 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 27578477 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 24573184 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 12574183 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12574183 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10645516 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6772302 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6550482 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24347426 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 24347426 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 24347426 — Biomarker: IGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF2; PP1446
Study 21098449 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 21098449 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18295412 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 20929599 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 8869674 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 12532366 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 12532366 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12532366 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23719148 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20499312 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 21757334 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22451449 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25877748 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17893579 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15591955 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7943835 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7943835 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3508193 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25185593 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25185593 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31648461 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 28533226 — Biomarker: IGF1R mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1R
Study 25643353 — Biomarker: FBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBP1; FBP
Study 25643353 — Biomarker: CNR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNR1; CNR
Study 21316089 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19635156 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 19635156 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19635156 — Biomarker: IMPDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IMPDH1; IMPD1
Study 29339649 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 29339649 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 10929163 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 25403903 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24771706 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14769778 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 12365087 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7983527 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 3142412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16803844 — Biomarker: TAOK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 12717216 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 28982517 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15933977 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15933977 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12856119 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 6153057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26482279 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26482279 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22827783 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29653858 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 21812797 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17640853 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 17640853 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 31739848 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29851204 — Biomarker: ISG15 mRNA
Type: Predictive Biomarker (PRD)
Genes: ISG15; G1P2; UCRP
Study 29851204 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9497787 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7930694 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29863451 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18061705 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 26777745 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26777745 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23842100 — Biomarker: Complement factor D
Type: Safety Biomarker (SAF)
Genes: CFD; DF; PFD
Study 12788993 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12788993 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12788993 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31420399 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27586837 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17391154 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23135976 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23135976 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20551485 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15240609 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15240609 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11816513 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 2880804 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23227315 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28939581 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28939581 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 21685235 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 21685235 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21685235 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 21685235 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21685235 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105