AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 30720004 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 25182660 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 25182660 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 25182660 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 16799799 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 29275583 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29275583 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 25171115 — Biomarker: LARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LARS1; KIAA1352; LARS
Study 23919441 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23919441 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23919441 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21701083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18307781 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18307781 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28485264 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28485264 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25472864 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 22537843 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2181841 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31837008 — Biomarker: CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR1; C3BR
Study 1602945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22301066 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10450299 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25239849 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11933550 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30016393 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 15071276 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2262216 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2262216 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 377932 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26615376 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 17983379 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9456999 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28780222 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26188020 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21969502 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 18335584 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 15589194 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 26421385 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 20818716 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 20818716 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 20818716 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 17666475 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17666475 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7865162 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 7046900 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 24760536 — Biomarker: PPARGC1A mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1
Study 24760536 — Biomarker: PRKAA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKAA2; AMPK; AMPK2
Study 24760536 — Biomarker: PRKAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKAG3; AMPKG3
Study 24760536 — Biomarker: NDUFS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NDUFS1
Study 24760536 — Biomarker: SDHA mRNA
Type: Predictive Biomarker (PRD)
Genes: SDHA; SDH2; SDHF
Study 24760536 — Biomarker: UQCRC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: UQCRC1
Study 24760536 — Biomarker: COX5B mRNA
Type: Predictive Biomarker (PRD)
Genes: COX5B
Study 24760536 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 24760536 — Biomarker: CPT1B mRNA
Type: Predictive Biomarker (PRD)
Genes: CPT1B; KIAA1670
Study 24760536 — Biomarker: HADH mRNA
Type: Predictive Biomarker (PRD)
Genes: HADH; HAD; HAD1; HADHSC; SCHAD
Study 10096255 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 29458401 — Biomarker: POR mRNA
Type: Predictive Biomarker (PRD)
Genes: POR; CYPOR
Study 29458401 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 22738299 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 20088810 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 18564199 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1604872 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 16390760 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10725861 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 1623678 — Biomarker: PDP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PDP1; PDP; PPM2C
Study 31046521 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 29755598 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 14560766 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 30349198 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study 27069169 — Biomarker: PPOX
Type: Safety Biomarker (SAF)
Genes: HCRT; OX
Study 24008819 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 23872591 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23872591 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17143000 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 17143000 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17143000 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 12809171 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19373973 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14746532 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 2204594 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 24502766 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 24502766 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 10048900 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 26220734 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26220734 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 19671303 — Biomarker: PCSK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK5; PC5; PC6
Study 19671303 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 19671303 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 9581727 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 7994817 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12846625 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 6492943 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6492943 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30206110 — Biomarker: Retinoblastoma-associated protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: RB1
Study 30206110 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 30206110 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17707382 — Biomarker: P2RY12 mRNA
Type: Predictive Biomarker (PRD)
Genes: P2RY12; HORK3
Study 31987371 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 31987371 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 31987371 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 28425253 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 28425253 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21760636 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9269759 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9269759 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 9269759 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26438518 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28579423 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 15085362 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 23159547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9756242 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2693499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27974308 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24002121 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24002121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24002121 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10779449 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 8622077 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 22318492 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22318492 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 11410120 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 29660936 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12829890 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 12829890 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9048263 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25766724 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 25766724 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 12360152 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 7538547 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30316907 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 26822324 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 23597077 — Biomarker: ENPP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ENPP2; ATX; PDNP2
Study 22333484 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 8784096 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25599737 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8865524 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6090020 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8370371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22561357 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 19886384 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15064097 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 15064097 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 23726433 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23726433 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 29141241 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 29141241 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24646100 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 8813039 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6399927 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 30188798 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 27319812 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 18243335 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 16012274 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 8653868 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 24178631 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 15955470 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2265368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26306400 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 26306400 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 26306400 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 9306168 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 8124120 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29275373 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23006063 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 29611221 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 19912315 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17351280 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 16324168 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2405804 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2405804 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30920620 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23360819 — Biomarker: LPIN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LPIN1; KIAA0188
Study 7921860 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 25204974 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 24634330 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 24634330 — Biomarker: ANGPTL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 24634330 — Biomarker: Angiopoietin-related protein 4
Type: Predictive Biomarker (PRD)
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 22582483 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22582483 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 12134253 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31551228 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23897424 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21768280 — Biomarker: N-acetylneuraminic acid
Type: Safety Biomarker (SAF)
Study 29435760 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 20856131 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20856131 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3662543 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 3662543 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 20952020 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31663986 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10584978 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30844804 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30844804 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22525206 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22525206 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22525206 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20581787 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20581787 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10487657 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26521100 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 19874179 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 9028057 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1506125 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 23541513 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 27585605 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 27585605 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 27585605 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 2979066 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22856504 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29112701 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23467946 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 12899584 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29937301 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15055472 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 6611603 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24225126 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12544508 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10481831 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 10481831 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10481831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8526782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31617025 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 31617025 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21228335 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 3277912 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21317163 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2149389 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18721344 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18721344 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10475304 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6528619 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 6528619 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 27359058 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 16446681 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 17895883 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15996602 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15482535 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12133355 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7620696 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26267747 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 26267747 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26267747 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26267747 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15051600 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 18083355 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG