AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 22046977 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30976888 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3904378 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3904378 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27498268 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20835904 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20835904 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23275364 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 23275364 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 26756540 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 18331218 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 11487258 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30157896 — Biomarker: MMD mRNA
Type: Predictive Biomarker (PRD)
Genes: MMD; PAQR11
Study 22785264 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 15942292 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 15942292 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 27000391 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21121983 — Biomarker: GSS mRNA
Type: Predictive Biomarker (PRD)
Genes: GSS
Study 18950932 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 18950932 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 18950932 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 17335331 — Biomarker: CGAS mRNA
Type: Predictive Biomarker (PRD)
Genes: CGAS; C6orf150; MB21D1
Study 21600518 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21600518 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21600518 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17908726 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31712768 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25488124 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25488124 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22730366 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16501017 — Biomarker: CHRM2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CHRM2
Study 15489091 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2786751 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 23429258 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 23429258 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14575730 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 9727892 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22615342 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20231684 — Biomarker: HSPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPB1; HSP27; HSP28
Study 15959668 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 2681593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12661806 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 9366582 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2439780 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2439780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27431654 — Biomarker: ADIPOQ mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 24855350 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21761341 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 15547086 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 11182190 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 10549446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2679978 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1252881 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8632537 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 25155608 — Biomarker: CEBPA mRNA
Type: Predictive Biomarker (PRD)
Genes: CEBPA; CEBP
Study 25155608 — Biomarker: ADIPOQ mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 25155608 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 25155608 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 22289222 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 25591433 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 25591433 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 25591433 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 17339748 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 11678486 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27458809 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20838060 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9403034 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 24252583 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20595155 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 20595155 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 18327093 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18327093 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6754210 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28585932 — Biomarker: REST mRNA
Type: Predictive Biomarker (PRD)
Genes: REST; NRSF; XBR
Study 25266695 — Biomarker: PAG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAG1; CBP; PAG
Study 21190079 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17068892 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12607650 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10665127 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1649575 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23241003 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19843671 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 19843671 — Biomarker: MTRR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTRR
Study 19843671 — Biomarker: EHMT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EHMT2; BAT8; C6orf30; G9A; KMT1C; NG36
Study 19843671 — Biomarker: PRDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRDM2; KMT8; RIZ
Study 19843671 — Biomarker: MLH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MLH1; COCA2
Study 19843671 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 11534420 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 26016859 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 26016859 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22456691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22456691 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16928979 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31067131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27564409 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25829346 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16652380 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 1691403 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1691403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28453740 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26319423 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 1511045 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 24709495 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24709495 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 24709495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15449975 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28501343 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28501343 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23582589 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 23582589 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20081225 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7484516 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 7484516 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 1851683 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 7177292 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 27286961 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 24984823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18561516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30246883 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 30246883 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 30246883 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 6985560 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 6985560 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24326780 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study 24030946 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21173180 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 21173180 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 27707440 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27707440 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26277173 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11590492 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26632428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1539851 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 7918310 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 14519051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22430266 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 22430266 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 12480610 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 13679496 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3880775 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 28145050 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 28145050 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 28145050 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 12620436 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 19995932 — Biomarker: Alpha-1-acid glycoprotein 1
Type: Monitoring Biomarker (MOI)
Genes: ORM1; AGP1
Study 24670704 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 12468337 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 12468337 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 29156909 — Biomarker: Ataxin-2
Type: Pharmacodynamic Biomarker (PDY)
Genes: ATXN2; ATX2; SCA2; TNRC13
Study 29156909 — Biomarker: AOAH mRNA
Type: Predictive Biomarker (PRD)
Genes: AOAH
Study 29156909 — Biomarker: GBGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GBGT1; UNQ2513/PRO6002
Study 19884468 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9869347 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 8018978 — Biomarker: N-acetylneuraminic acid
Type: Safety Biomarker (SAF)
Study 2685599 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2685599 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2685599 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15627789 — Biomarker: CGN mRNA
Type: Predictive Biomarker (PRD)
Genes: CGN; KIAA1319
Study 27126851 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 27126851 — Biomarker: FKBP5 mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: FKBP5; AIG6; FKBP51
Study 27126851 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 27126851 — Biomarker: ANKK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANKK1; PKK2; SGK288
Study 8327595 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 3755281 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 27234671 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23291317 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23291317 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10946527 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10946527 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9063919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29119331 — Biomarker: CRAT mRNA
Type: Predictive Biomarker (PRD)
Genes: CRAT; CAT1
Study 24974817 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 10852597 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23301476 — Biomarker: C4A mRNA
Type: Predictive Biomarker (PRD)
Genes: C4A; CO4; CPAMD2
Study 8698446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24700342 — Biomarker: STAT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT4
Study 18724827 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16622803 — Biomarker: Mitochondrial membrane potential
Type: Pharmacodynamic Biomarker (PDY)
Study 12670840 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 20708715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16782924 — Biomarker: RTL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RTL1; MAR1; MART1; PEG11
Study 16782924 — Biomarker: MAGEA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAGEA3; MAGE3
Study 9534750 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9534750 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 10999790 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 10999790 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31601493 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 24742498 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21614479 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 19580461 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19506174 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19506174 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21402547 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21402547 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 10871909 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8508996 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27602508 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 25341478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17289483 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17289483 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17289483 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 12574871 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 12574871 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3781985 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30238915 — Biomarker: NE
Type: Predictive Biomarker (PRD)
Study 23519822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20386016 — Biomarker: MAP2K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K1; MEK1; PRKMK1
Study 12897739 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 8855830 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8855830 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19414584 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9134274 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9134274 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 25889222 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7810816 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2853765 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2853765 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15642557 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 15642557 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15642557 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30599367 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 16724678 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 24293166 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 9169747 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9169747 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 29328860 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 27206939 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 25052061 — Biomarker: MEST mRNA
Type: Predictive Biomarker (PRD)
Genes: MEST; PEG1
Study 9715790 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 9715790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7866465 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7866465 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30925951 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30925951 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 30925951 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25788492 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25788492 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 23688546 — Biomarker: SPR mRNA
Type: Predictive Biomarker (PRD)
Genes: SPR
Study 17904221 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 17904221 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9653567 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9653567 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9989682 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 2183733 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31468659 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26484767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)