AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 11046211 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 3024826 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 30913065 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 28391875 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 28391875 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28391875 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19111610 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15259281 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31872213 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31872213 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25601933 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16287453 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16287453 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 16287453 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29902061 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23924446 — Biomarker: GLI2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLI2; THP
Study 29532734 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29532734 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29436152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22773291 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 19965548 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 8675360 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1677616 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 25008950 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25008950 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25008950 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25008950 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 25008950 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31248843 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 24996030 — Biomarker: DSP mRNA
Type: Predictive Biomarker (PRD)
Genes: DSP
Study 24996030 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20473067 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 11874442 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11874442 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2185342 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 6938013 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 28880609 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18438718 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18438718 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11314834 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9388088 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19515542 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 24895339 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 24895339 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20833266 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25626066 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 9924466 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3041248 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3041248 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 23652778 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23652778 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19074543 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25733317 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25733317 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 11373411 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11373411 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3319111 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24737678 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 11429337 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9531030 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 9531030 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30472196 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24968500 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16520405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24312450 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20299470 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 3932077 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 3932077 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 26642301 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 9287967 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 21692299 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3739357 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11470697 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7921444 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 20473630 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20473630 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20305926 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 20305926 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 17985505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23182947 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 15809819 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11179831 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 16598851 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 8304709 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 23591255 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10912543 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10912543 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10912543 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8793024 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 6228459 — Biomarker: CLYBL mRNA
Type: Predictive Biomarker (PRD)
Genes: CLYBL; CLB
Study 26332605 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9769871 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6786115 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22995971 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 11851660 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11851660 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2965227 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31955619 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12161047 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6393417 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31536101 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 11932276 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9795409 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 26072330 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 16504645 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16504645 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16504645 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 15246125 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 8358980 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27167103 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24309322 — Biomarker: PCDH10 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCDH10; KIAA1400
Study 24309322 — Biomarker: SPARC mRNA
Type: Predictive Biomarker (PRD)
Genes: SPARC; ON
Study 24309322 — Biomarker: UCHL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCHL1
Study 24309322 — Biomarker: PCDH10
Type: Predictive Biomarker (PRD)
Genes: OL-PCDH; KIAA1400
Study 18037940 — Biomarker: HDC mRNA
Type: Predictive Biomarker (PRD)
Genes: HDC
Study 10390385 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 31368057 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19534023 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17024220 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9643274 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9643274 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9643274 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 3414729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28606731 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17881183 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 12213869 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9810030 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9810030 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2667311 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2667311 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 2667311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24152981 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 15246460 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11734428 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 7695928 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 30482135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28225050 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25166221 — Biomarker: Urine free cortisol
Type: Surrogate Endpoint (SUR)
Study 27765726 — Biomarker: POU2F1 mRNA
Type: Predictive Biomarker (PRD)
Genes: POU2F1; OCT1; OTF1
Study 21987386 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18824714 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18824714 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11874164 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26214887 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 23953056 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20687305 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 19090877 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19090877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9076210 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26111104 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26111104 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 21246188 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 19906504 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25711323 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8625134 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23348071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19147457 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16490090 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 26619202 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26619202 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23871259 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 11753267 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 23098170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6828614 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16822563 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16249527 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11878059 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11878059 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11878059 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29601904 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 18296554 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9225069 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 27245042 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16715189 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 15278206 — Biomarker: CNR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNR1; CNR
Study 29643323 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 9267667 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12809965 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11182393 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 323023 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22551950 — Biomarker: PNPLA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PNPLA2; ATGL; FP17548
Study 22551950 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10521742 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29138226 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 29138226 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 25060690 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10516540 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 24359456 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 24359456 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 24359456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19786805 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 19786805 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 17442226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9689424 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25594355 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16514482 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 22173570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19906800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2792112 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29153546 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 29153546 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9808550 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23154577 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21632504 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17101607 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9203190 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24598116 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 12575587 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 12575587 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11747061 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28287413 — Biomarker: GHR mRNA
Type: Predictive Biomarker (PRD)
Genes: GHR
Study 28287413 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 24483106 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19903376 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19903376 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19903376 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15491387 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15491387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6137231 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28902116 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28902116 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 30591380 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26228536 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 21982411 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 21982411 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 11029965 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 11029965 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 9095122 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 29128682 — Biomarker: MUC5AC mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MUC5AC; MUC5
Study 24022270 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 24022270 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8931343 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3956056 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3956056 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27681755 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 22992240 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 27362956 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25230867 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19291790 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 16218176 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12117728 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12117728 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 388053 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400