AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 10727924 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 8772689 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 21962090 — Biomarker: NSMAF mRNA
Type: Predictive Biomarker (PRD)
Genes: NSMAF; FAN
Study 28666310 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17761977 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24236646 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16689181 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 20406241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10580197 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7593700 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 21130513 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 15066879 — Biomarker: SDC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SDC1; SDC
Study 9863994 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 9863994 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29354913 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18978388 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8727868 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 8727868 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24370761 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15199366 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 11383595 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11383595 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31005374 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16402242 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 9363870 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 1586618 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 3839679 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31704907 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29310138 — Biomarker: MMD mRNA
Type: Predictive Biomarker (PRD)
Genes: MMD; PAQR11
Study 12494803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12494803 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 2920500 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1082383 — Biomarker: FUT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FUT1; H; HSC
Study 16469601 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 11295378 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 29289540 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 9050631 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9050631 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 29074542 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 26333723 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 30194492 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 30245148 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28531784 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28531784 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 9714995 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 9714995 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9714995 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12783289 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19464064 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 22353804 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 22353804 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 14687173 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 2683921 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2683921 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23224298 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 22089305 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 8732376 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 2009146 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2009146 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28798999 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 9020454 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8481587 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25791185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15596634 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15596634 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15596634 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15596634 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12606735 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 29352723 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22251482 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22251482 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 17192289 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 7706983 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 11167663 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11167663 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7488463 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6996483 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 9006811 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6376209 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31085948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24643119 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 24643119 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 22295813 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 22295813 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 20814848 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17491103 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 14983409 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 21410033 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 15830009 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 15830009 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 22429354 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 21890085 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19052047 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 15762970 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 339214 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23593633 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 19820017 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19820017 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 16829029 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15277409 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15277409 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 23743162 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14610641 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31566309 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 19553931 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 19553931 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15015147 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 17415030 — Biomarker: CLNK mRNA
Type: Predictive Biomarker (PRD)
Genes: CLNK; MIST
Study 31859245 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 17376548 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30672196 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 30672196 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 20472253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29972000 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 12077684 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 8749880 — Biomarker: MAF mRNA
Type: Predictive Biomarker (PRD)
Genes: MAF
Study 8749880 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 2522723 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10720278 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 30474909 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11136913 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30829679 — Biomarker: EED mRNA
Type: Predictive Biomarker (PRD)
Genes: EED
Study 24294684 — Biomarker: UCN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCN3; SPC
Study 18270751 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16487947 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 11051235 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11051235 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 2863676 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31345167 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12391054 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12391054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21541815 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 11870241 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 11870241 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 46021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25138607 — Biomarker: NRF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRF1
Study 25138607 — Biomarker: SLC27A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC27A4; ACSVL4; FATP4
Study 25138607 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 25138607 — Biomarker: miR-29a
Type: Monitoring Biomarker (MOI)
Genes: MIR29A
Study 15087948 — Biomarker: Serum asparaginase
Type: Surrogate Endpoint (SUR)
Study 11840364 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30898984 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 30898984 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 30898984 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 24002370 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24002370 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21924874 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 31673364 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 25672513 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16115944 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 16115944 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 16115944 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16115944 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11849865 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11849865 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10094146 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 6142645 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6142645 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25306749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20139221 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 15635619 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10208247 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6318545 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8535536 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8535536 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21271793 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21271793 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19432566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11747872 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 9413765 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 18753925 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18753925 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15961987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15961987 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22217192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16259286 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 7479227 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 7479227 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7479227 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2205694 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 9779838 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 9779838 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 7512131 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 28318077 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23011321 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 23011321 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18261121 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 30293689 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 30293689 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 29931076 — Biomarker: TLR8 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR8; UNQ249/PRO286
Study 18648963 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9432038 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 23653149 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20691795 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30488542 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15943593 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 12680748 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28708126 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26068295 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24727329 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24727329 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 20671333 — Biomarker: AARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AARS1; AARS
Study 11548847 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 11548847 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 7799246 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 9198713 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19064562 — Biomarker: CYP19A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 10657837 — Biomarker: LTB mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB; TNFC; TNFSF3
Study 30084103 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 30084103 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 16107949 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 4412442 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30883861 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20795924 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2569857 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26222725 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11147785 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 7503064 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11881128 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2149513 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25557347 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23591713 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19669785 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19669785 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 8198020 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10026395 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 1853306 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 27511899 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 27511899 — Biomarker: miR-155
Type: Safety Biomarker (SAF)
Genes: MIR155
Study 28318619 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21594560 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 17211242 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9692813 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 20146674 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20146674 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20146674 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20146674 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26352164 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22025372 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17492948 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 11499745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29504468 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25709408 — Biomarker: Carbonic anhydrase IX
Type: Predictive Biomarker (PRD)
Genes: CA9; G250; MN
Study 23510162 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 16574032 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 2951925 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17585405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16297553 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16297553 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12066254 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8749950 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25740264 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4