AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23537462 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 14712421 — Biomarker: RCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RCN1; RCN
Study 14712421 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21902686 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 21902686 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8726152 — Biomarker: MMD mRNA
Type: Predictive Biomarker (PRD)
Genes: MMD; PAQR11
Study 31655296 — Biomarker: CDK6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK6; CDKN6
Study 31655296 — Biomarker: RBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBL2; RB2
Study 31655296 — Biomarker: Retinoblastoma-associated protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: RB1
Study 31655296 — Biomarker: Aurora kinase A
Type: Predictive Biomarker (PRD)
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 22181685 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 22181685 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19907002 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 19907002 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 19907002 — Biomarker: TFAM mRNA
Type: Predictive Biomarker (PRD)
Genes: TFAM; TCF6; TCF6L2
Study 19907002 — Biomarker: NKRF mRNA
Type: Predictive Biomarker (PRD)
Genes: NKRF; ITBA4; NRF
Study 8583019 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 28027911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25692980 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 31262847 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25582279 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 30958572 — Biomarker: Ataxin-2
Type: Pharmacodynamic Biomarker (PDY)
Genes: ATXN2; ATX2; SCA2; TNRC13
Study 25314964 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study 15111142 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27402556 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 1942470 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 1942470 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 24102416 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17552881 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15919731 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15919731 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14526208 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8893678 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 8893678 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study 8893678 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8393589 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27977392 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27977392 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25496294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31027457 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31027457 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31027457 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 24858870 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 24858870 — Biomarker: DSE mRNA
Type: Predictive Biomarker (PRD)
Genes: DSE; SART2
Study 22067410 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 22067410 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 22067410 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 9815203 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7813605 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 2700321 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30955978 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 30955978 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28525305 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 28525305 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 28525305 — Biomarker: BCL6 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 23187956 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23187956 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23187956 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23187956 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23187956 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 16530578 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 3332119 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29306057 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29306057 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 12139873 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 31044748 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 30616740 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 30616740 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 18842668 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 3311119 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25615445 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 6423063 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 27049176 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 27049176 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 27049176 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22377540 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 20350990 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 8622076 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24657555 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24657555 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17319791 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3094355 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3094355 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10382190 — Biomarker: INPP5D mRNA
Type: Predictive Biomarker (PRD)
Genes: INPP5D; SHIP; SHIP1
Study 8730971 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23360820 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 18025996 — Biomarker: SLPI mRNA
Type: Predictive Biomarker (PRD)
Genes: SLPI; WAP4; WFDC4
Study 7737631 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 19690618 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 9041214 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9041214 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 26061222 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 23884332 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 12324677 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 12324677 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 8963481 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 18421281 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 18421281 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18421281 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18421281 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12640069 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 29617523 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26721833 — Biomarker: HDGFL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: HDGFL2; HDGF2; HDGFRP2; HRP2; UNQ785/PRO1604
Study 10571797 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 1428437 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 20473737 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20473737 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20473737 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14990557 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 25727860 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22048712 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11379675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3606929 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23988791 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 23988791 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23988791 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 15481651 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10343151 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 10343151 — Biomarker: OMD mRNA
Type: Predictive Biomarker (PRD)
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 7498102 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 18533934 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9715775 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9715775 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 28472101 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 14999204 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11707555 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14605518 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10394887 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26164864 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26164864 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23657083 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 23657083 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 23657083 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19628934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29650764 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 29650764 — Biomarker: SNN mRNA
Type: Predictive Biomarker (PRD)
Genes: SNN
Study 29650764 — Biomarker: TXNDC11 mRNA
Type: Predictive Biomarker (PRD)
Genes: TXNDC11; EFP1
Study 29650764 — Biomarker: CHD9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHD9; KIAA0308; KISH2; PRIC320; AD-013; x0008
Study 29650764 — Biomarker: GHR mRNA
Type: Predictive Biomarker (PRD)
Genes: GHR
Study 29650764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20467269 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10759875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30789801 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10837289 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 1671471 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6468768 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 30253712 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26620123 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 17617807 — Biomarker: CCL18 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 8876936 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8876936 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 1524654 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 30745277 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 18625518 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 10429977 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10429977 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 10429977 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 10429977 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7481190 — Biomarker: MAP3K10 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP3K10; MLK2; MST
Study 18850387 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 14535021 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 22551036 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 22551036 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 19703824 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17038243 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17038243 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12812018 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 3299016 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28624696 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9034258 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30700946 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 30376755 — Biomarker: INPP5K mRNA
Type: Predictive Biomarker (PRD)
Genes: INPP5K; PPS; SKIP
Study 10559703 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 18001178 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 805050 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28617807 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19713654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17908769 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17908769 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17908769 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 17908769 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 17908769 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 21663696 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21663696 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 19067057 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19067057 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 3912001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22265923 — Biomarker: DCC mRNA
Type: Predictive Biomarker (PRD)
Genes: DCC; IGDCC1
Study 22265923 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31654328 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 28026912 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 9072981 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29482662 — Biomarker: LTB4R mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 26215765 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16549077 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 16549077 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 1957404 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31393225 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27785737 — Biomarker: SYK mRNA
Type: Predictive Biomarker (PRD)
Genes: SYK
Study 27785737 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 27785737 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21742400 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21742400 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21742400 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 16772765 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7769367 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 7769367 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 2178657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11713439 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 6372133 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21368391 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19357525 — Biomarker: L-acetylcarnitine
Type: Safety Biomarker (SAF)
Study 15159241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3098772 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 20843737 — Biomarker: SLC10A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC10A3; DXS253E; P3
Study 18946458 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 12673143 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8842828 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 8471375 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8471375 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 30275282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27130973 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24351072 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 24351072 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8982555 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8982555 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31539378 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31539378 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 12082590 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 7595759 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17634167 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 17634167 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 17634167 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 17634167 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17634167 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 26695077 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 8538187 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 38678 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21857276 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 8076486 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 11136688 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28025372 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)