AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24396625 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 24398331 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 24398331 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24398331 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24400847 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24406779 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24407191 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 24410126 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 24410943 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24414130 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24414130 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24416138 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 24416138 — Biomarker: PDGFRA
Type: Predictive Biomarker (PRD)
Genes: CD140a; PDGFR2; GAS9
Study 24417980 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24418731 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24419411 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24420643 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 24420643 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 24420643 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 24420643 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 24420643 — Biomarker: CD24 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD24; CD24A
Study 24420643 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 24420643 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24422672 — Biomarker: KIAA1549 mRNA
Type: Predictive Biomarker (PRD)
Genes: KIAA1549
Study 24422672 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 24422672 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 24422672 — Biomarker: CDKN2A mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2A; CDKN2; MTS1
Study 24422782 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 24423045 — Biomarker: POR mRNA
Type: Predictive Biomarker (PRD)
Genes: POR; CYPOR
Study 24423476 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24423745 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24429311 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24429337 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 24430093 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24431228 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 24431909 — Biomarker: Hemoglobin response rate
Type: Surrogate Endpoint (SUR)
Study 24433481 — Biomarker: ABCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 24433481 — Biomarker: MRP2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ABCC2; DJS; cMRP
Study 24435003 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24436111 — Biomarker: ATP1A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATP1A3
Study 24438342 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24438342 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24439297 — Biomarker: CHM mRNA
Type: Predictive Biomarker (PRD)
Genes: CHM; REP1; TCD
Study 24440112 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24440279 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24443277 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 24444339 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 24444339 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 24445353 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 24445353 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24446519 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24446656 — Biomarker: GIPR mRNA
Type: Predictive Biomarker (PRD)
Genes: GIPR
Study 24446656 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 24446656 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24446658 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24452746 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 24452753 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 24456358 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 24456358 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24456695 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 24457244 — Biomarker: BRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRD4; HUNK1
Study 24457379 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24457379 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24458353 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 24458953 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24458953 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24458953 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24458953 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 24459219 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 24459612 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24459612 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 24460746 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 24461715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24463454 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 24464121 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 24464355 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 24464355 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24464597 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 24464944 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 24465572 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24467603 — Biomarker: PTGES2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGES2; C9orf15; PGES2
Study 24467603 — Biomarker: PTGER4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGER4; PTGER2
Study 24467979 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 24470004 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24470004 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24470398 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 24472814 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 24472814 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 24472814 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 24474568 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 24475922 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 24475922 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24476740 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 24477042 — Biomarker: GCKR mRNA
Type: Predictive Biomarker (PRD)
Genes: GCKR
Study 24477042 — Biomarker: PNPLA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PNPLA3; ADPN; C22orf20
Study 24480627 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 24481647 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24484754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24484754 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 24487484 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24488560 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 24488798 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 24490070 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 24492296 — Biomarker: CD70 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD70; CD27L; CD27LG; TNFSF7
Study 24492296 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 24493150 — Biomarker: FMOD mRNA
Type: Predictive Biomarker (PRD)
Genes: FMOD; FM; SLRR2E
Study 24493150 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 24493157 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24493157 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 24493287 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 24493287 — Biomarker: LAMC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMC2; LAMB2T; LAMNB2
Study 24493717 — Biomarker: Zinc finger protein GLI1
Type: Predictive Biomarker (PRD)
Genes: GLI1; GLI
Study 24495202 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 24495442 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24497495 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 24498123 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 24499022 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24499098 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24499496 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24500145 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 24500155 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24501009 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24501009 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24501009 — Biomarker: ERBB4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB4; HER4
Study 24501009 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 24504442 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 24504737 — Biomarker: DMRT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DMRT2; DSXL2
Study 24504737 — Biomarker: TP53I13 mRNA
Type: Predictive Biomarker (PRD)
Genes: TP53I13; DSCP1
Study 24506412 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 24506509 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 24507585 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24508104 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 24508104 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 24508104 — Biomarker: CCND1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND1; BCL1; PRAD1
Study 24508104 — Biomarker: FGFR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 24508104 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24508104 — Biomarker: MDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM2
Study 24508104 — Biomarker: FGFR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR2; BEK; KGFR; KSAM
Study 24508104 — Biomarker: AKT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT2
Study 24508104 — Biomarker: IGF1R mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1R
Study 24508104 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 24508444 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24508444 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 24508444 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 24508444 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 24508444 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24515598 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 24515598 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 24515598 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24516013 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 24520093 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24522446 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24523212 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 24523241 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 24524285 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 24524285 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 24525446 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 24528219 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24529158 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 24529163 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24529291 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24529936 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24530759 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24531550 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24533707 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 24534286 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24535278 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24535278 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 24535278 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24535278 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24535655 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 24552750 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24554062 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 24555130 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 24555723 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 24558979 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 24559067 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24559465 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 24559465 — Biomarker: IGFBP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP7; MAC25; PSF
Study 24559843 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24561125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24564178 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24564178 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24566706 — Biomarker: ALK
Type: Predictive Biomarker (PRD)
Genes: CD246; ALK1
Study 24566706 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24566706 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24566706 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 24566733 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 24566733 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 24567804 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24567804 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24567843 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 24568177 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24568177 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24568177 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24568613 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 24569099 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 24571752 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 24571916 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 24573552 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24573552 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 24574344 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 24574344 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 24574344 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 24574344 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 24576876 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24577164 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24577164 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24577164 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 24577164 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 24577564 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 24577748 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 24579662 — Biomarker: VHL mRNA
Type: Predictive Biomarker (PRD)
Genes: VHL
Study 24582005 — Biomarker: SGSH mRNA
Type: Predictive Biomarker (PRD)
Genes: SGSH; HSS
Study 24582673 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 24585716 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24590637 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 24590653 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 24590653 — Biomarker: DCX mRNA
Type: Predictive Biomarker (PRD)
Genes: DCX; DBCN; LISX
Study 24593248 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24594870 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 24595221 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24595221 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24595454 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 24597865 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 24597865 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24599770 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24600548 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24600548 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24600548 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 24600548 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 24603195 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 24604476 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 24604486 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1