AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24924232 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24924232 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19767812 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19767812 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7756106 — Biomarker: SLC38A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC38A3; G17; NAT1; SN1; SNAT3
Study 21763472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15603203 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2884860 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30371278 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25996101 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 23213070 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 19880460 — Biomarker: STAR mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAR; STARD1
Study 8333814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26286128 — Biomarker: PICALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PICALM; CALM
Study 23743161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23743161 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 23743161 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23743161 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16856623 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16856623 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31755803 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 28643618 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 23306828 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 6233093 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25057809 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25057809 — Biomarker: SOD2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SOD2
Study 25057809 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 25057809 — Biomarker: GPX4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPX4
Study 25057809 — Biomarker: TXN mRNA
Type: Predictive Biomarker (PRD)
Genes: TXN; TRDX; TRX; TRX1
Study 25057809 — Biomarker: TXNRD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TXNRD1; GRIM12; KDRF
Study 22761409 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 20465650 — Biomarker: MITF mRNA
Type: Predictive Biomarker (PRD)
Genes: MITF; BHLHE32
Study 20465650 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 18703472 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15851913 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15851913 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15851913 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12576957 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9804518 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 197800 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9771208 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8116547 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8116547 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28350328 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28350328 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17690547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15161435 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15702625 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15702625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9352972 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29239893 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28145966 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26637993 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12952111 — Biomarker: CAMP mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMP; CAP18; FALL39; HSD26
Study 10372699 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7237025 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 27525817 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15682483 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10598660 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20375791 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 6837242 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 29336387 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29336387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19643620 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2338698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19236805 — Biomarker: CBR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CBR1; CBR; CRN; SDR21C1
Study 2733576 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27743738 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 24614165 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19996728 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19167590 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19167590 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 15500196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30398957 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 24837466 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 24837466 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 15101020 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12234946 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12234946 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25928131 — Biomarker: UBXN11 mRNA
Type: Predictive Biomarker (PRD)
Genes: UBXN11; SOC; UBXD5; PP2243
Study 22089773 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11316896 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31206613 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 28729158 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28729158 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study 23732643 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 21823280 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20082923 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27058753 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 22770683 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20043983 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11895470 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2644151 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 21705552 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12771320 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 8175200 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 26718095 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1826253 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 1826253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29793488 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29793488 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29793488 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15121020 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18840641 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27955995 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 27955995 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19528362 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27933720 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 7502282 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 6256422 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 24723075 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19708636 — Biomarker: SLMAP mRNA
Type: Predictive Biomarker (PRD)
Genes: SLMAP; KIAA1601; SLAP; UNQ1847/PRO3577
Study 17417700 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9589688 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29182708 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27140797 — Biomarker: FFAR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FFAR1; GPR40
Study 31090592 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 23354282 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20658564 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20658564 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 165029 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28723333 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21603894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2439568 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 25617503 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 25617503 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 18928094 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18928094 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 18928094 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18928094 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 8547558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8547558 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 24445757 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 24445757 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19638648 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 17289479 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6604469 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 28143739 — Biomarker: Angiopoietin-1
Type: Monitoring Biomarker (MOI)
Genes: ANGPT1; KIAA0003
Study 28143739 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8385478 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26264387 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 23053255 — Biomarker: CDK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK5; CDKN5; PSSALRE
Study 23053255 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 16059590 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 7733040 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1682593 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 21249385 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21249385 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27951511 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 25709428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20962290 — Biomarker: Synuclein alpha
Type: Pharmacodynamic Biomarker (PDY)
Genes: SNCA; NACP; PARK1
Study 2070108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21354370 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19406658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25296725 — Biomarker: CHEK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHEK1; CHK1
Study 25296725 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 17544264 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8035028 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30372675 — Biomarker: L1CAM mRNA
Type: Predictive Biomarker (PRD)
Genes: L1CAM; CAML1; MIC5
Study 30372675 — Biomarker: NRGN mRNA
Type: Predictive Biomarker (PRD)
Genes: NRGN
Study 30372675 — Biomarker: Neuromodulin
Type: Pharmacodynamic Biomarker (PDY)
Genes: GAP43
Study 11872674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21144505 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21144505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18083781 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 8241095 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2862810 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31881614 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 26630547 — Biomarker: SERPINA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA2; ARGS; ATR; PIL; SERPINA2P
Study 26541842 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 31907186 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 22206795 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22206795 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 22206795 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12364632 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29975270 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 10502590 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9712239 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 9712239 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 26195265 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 21348806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14614218 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 4082295 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 21265353 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15591305 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 6365409 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28602779 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 25989338 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24099474 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 17000930 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17000930 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3116132 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26599376 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 23820669 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 23820669 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 23820669 — Biomarker: c-Jun N-terminal kinase
Type: Safety Biomarker (SAF)
Study 19238075 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12602908 — Biomarker: DCT mRNA
Type: Predictive Biomarker (PRD)
Genes: DCT; TYRP2
Study 8350342 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22987918 — Biomarker: SLC4A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC4A5; NBC4
Study 22987918 — Biomarker: GRK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRK4; GPRK2L; GPRK4
Study 18949104 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10849524 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 28724547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25538178 — Biomarker: BTC mRNA
Type: Predictive Biomarker (PRD)
Genes: BTC
Study 23161001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19238452 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16918945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23569311 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23569311 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23569311 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19500335 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28535076 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 23122652 — Biomarker: CD52 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD52; CDW52; HE5
Study 18075302 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18075302 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 18075302 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 15625138 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12163426 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8942423 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8942423 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8942423 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7950459 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30387374 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 20470671 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20470671 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20470671 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15998268 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 11094001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9010701 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 28106552 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 21931077 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19145932 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8941507 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8941507 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30796338 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15019892 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11260155 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 11260155 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9731049 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20