AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31299352 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 26378687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15001195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15001195 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2873440 — Biomarker: PCLAF mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 31802559 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29760009 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 6407047 — Biomarker: SPR mRNA
Type: Predictive Biomarker (PRD)
Genes: SPR
Study 6407047 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 31254340 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 31254340 — Biomarker: NANOS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS3; NOS3
Study 31254340 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20590736 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 16270633 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 24766179 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17261462 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12593999 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 28942094 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 28942094 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 19524176 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 3132428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26475802 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 7804386 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31799628 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 24047763 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16741261 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8404942 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3027601 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12842988 — Biomarker: RARA mRNA
Type: Predictive Biomarker (PRD)
Genes: RARA; NR1B1
Study 12842988 — Biomarker: RUNX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX1; AML1; CBFA2
Study 12842988 — Biomarker: RUNX1T1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study 12842988 — Biomarker: MYH11 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MYH11; KIAA0866
Study 8741364 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8741364 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26297029 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9891197 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2454355 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27875516 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8334339 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 30129815 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 24022919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17446206 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28276001 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16525816 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 16525816 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 16525816 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 12740037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10740549 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1577399 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22314458 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17587394 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17587394 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7634283 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2454357 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25792708 — Biomarker: BET1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BET1
Study 17379979 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8720348 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2565841 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3093 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21663648 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 16728452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17396618 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 7725883 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19409578 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 19409578 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 26912543 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 20646510 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17959591 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 17959591 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14617323 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 14617323 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 23019944 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19318455 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11599198 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31712617 — Biomarker: CA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA4
Study 31712617 — Biomarker: CA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA1
Study 31712617 — Biomarker: CA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA2
Study 22003869 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 8312032 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18000162 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18000162 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15882894 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8873580 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 8873580 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 1526086 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26924381 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20536790 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 20536790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9426022 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2469711 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 26352813 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21836088 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16758644 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7587254 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31715161 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23124798 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 21044166 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 17531578 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17531578 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17531578 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15768732 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9740159 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27939076 — Biomarker: LOXL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LOXL2
Study 25545744 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 17580441 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27695978 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27695978 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29797695 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 29797695 — Biomarker: miR-223
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR223
Study 29797695 — Biomarker: miR-135a
Type: Predictive Biomarker (PRD)
Study 16647506 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 2857087 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17512795 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 16138333 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 16138333 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7791814 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30531419 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 30531419 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27004301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 332100 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31281056 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 28011155 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28011155 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28011155 — Biomarker: Vascular endothelial cadherin
Type: Safety Biomarker (SAF)
Genes: CDH5
Study 9151915 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30346850 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31146493 — Biomarker: SDC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SDC1; SDC
Study 27356547 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24785136 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21288350 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18849016 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12423518 — Biomarker: Protein AMBP
Type: Safety Biomarker (SAF)
Genes: AMBP; HCP; ITIL
Study 12423518 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 30006305 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23942869 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17369807 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31590286 — Biomarker: MMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP2; CLG4A
Study 28697789 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28697789 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 28697789 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 28697789 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21989078 — Biomarker: SLC22A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A2; OCT2
Study 21989078 — Biomarker: SLC47A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC47A1; MATE1
Study 21989078 — Biomarker: SLC29A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC29A4; ENT4; PMAT; PSEC0113
Study 8727681 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 6119558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31806191 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 7937272 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17465700 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 17465700 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 16810279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9476862 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 9476862 — Biomarker: Nasal potential difference
Type: Pharmacodynamic Biomarker (PDY)
Study 27072880 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 19079943 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 19079943 — Biomarker: RUNX1T1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study 15179192 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 26534930 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 8179048 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31932084 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 31932084 — Biomarker: APOB mRNA
Type: Predictive Biomarker (PRD)
Genes: APOB
Study 27632197 — Biomarker: ALDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH2; ALDM
Study 16084803 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16084803 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12451009 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8384659 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 30666367 — Biomarker: SMO mRNA
Type: Predictive Biomarker (PRD)
Genes: SMO; SMOH
Study 19372524 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16761194 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26860879 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 9485066 — Biomarker: ATXN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATXN1; ATX1; SCA1
Study 28251152 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 27504739 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 27504739 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24997826 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 24997826 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 20863330 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7733026 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30878017 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 16983507 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 16276165 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30068285 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 28064113 — Biomarker: SRM mRNA
Type: Predictive Biomarker (PRD)
Genes: SRM; SPS1; SRML1
Study 14671407 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10193729 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 1975526 — Biomarker: HINT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HINT1; HINT; PKCI1; PRKCNH1
Study 31495497 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 20887370 — Biomarker: SV2A mRNA
Type: Predictive Biomarker (PRD)
Genes: SV2A; KIAA0736; PSEC0174
Study 19371826 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15155310 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 11686425 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 11686425 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 11686425 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 8290386 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 8290386 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 8290386 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 2845769 — Biomarker: CAMP mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMP; CAP18; FALL39; HSD26
Study 21332970 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 16312168 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 25043636 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24526136 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24526136 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20140250 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20140250 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 14721990 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14721990 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10982756 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8736279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22917623 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 21791470 — Biomarker: MAGEC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAGEC1
Study 21791470 — Biomarker: MAGEB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAGEB2
Study 21791470 — Biomarker: MAGEA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAGEA6; MAGE6
Study 21791470 — Biomarker: NUF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUF2; CDCA1; NUF2R
Study 21791470 — Biomarker: MAGEA9 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAGEA9; MAGE9; MAGEA9A; MAGEA9B
Study 21791470 — Biomarker: CTAG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CTAG2; ESO2; LAGE1
Study 16846539 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12766755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31339403 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 27544584 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24871666 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22365947 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 22365947 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12174378 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 17519642 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 15471832 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 8094168 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25605843 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 25605843 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 25605843 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 23263176 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16797388 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 16797388 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 6429229 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 10445600 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30579966 — Biomarker: NRM mRNA
Type: Predictive Biomarker (PRD)
Genes: NRM; NRM29; UNQ555/PRO1112
Study 30579966 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20435238 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18544168 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14715345 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 11689803 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 9297428 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 31942840 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26811103 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24812309 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 22102701 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28659293 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21835957 — Biomarker: NOTCH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOTCH1; TAN1
Study 21835957 — Biomarker: BAALC mRNA
Type: Predictive Biomarker (PRD)
Genes: BAALC