AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 19164269 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2492674 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 26010632 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 15166883 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 9630024 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25123562 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21914136 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 1439640 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31615996 — Biomarker: MMP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP7; MPSL1; PUMP1
Study 22582911 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 17155971 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11856461 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 11856461 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 28071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7729044 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 21860000 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 17925885 — Biomarker: PIGA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIGA
Study 17925885 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 15514875 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 31079555 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31079555 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31079555 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19555037 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17004893 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30144099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18159148 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18486419 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 12775312 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20209619 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 10748449 — Biomarker: PRLR mRNA
Type: Predictive Biomarker (PRD)
Genes: PRLR
Study 29342453 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29342453 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29342453 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 29342453 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 29342453 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 29342453 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 29342453 — Biomarker: TLR2
Type: Predictive Biomarker (PRD)
Genes: TIL4; CD282
Study 29342453 — Biomarker: miR-21-5p
Type: Predictive Biomarker (PRD)
Genes: MIR21
Study 29342453 — Biomarker: miR-187
Type: Predictive Biomarker (PRD)
Genes: MIR187
Study 29342453 — Biomarker: miR-146a
Type: Safety Biomarker (SAF)
Genes: MIR146A
Study 16186434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28074798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12784100 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 24456362 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 25095746 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25095746 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25095746 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 25095746 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25095746 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 19363969 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 19363969 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 2462943 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28254959 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 23529704 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23529704 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21948693 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study 21597981 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11928041 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11928041 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11928041 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20886228 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 17035446 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10373062 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8901839 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 8901839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21478189 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21478189 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23630950 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30636547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30215466 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26579834 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22408779 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12120883 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 7790606 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 29220533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22271072 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22271072 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 498698 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 29100199 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24794093 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15204794 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 27981552 — Biomarker: Succinate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: SDHD
Study 25071075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10493664 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 10493664 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8670596 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8670596 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 2872795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30176543 — Biomarker: EPHA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPHA2; ECK
Study 25352653 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21402550 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21402550 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 19858379 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 19858379 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 28389218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25591836 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25591836 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 12658367 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 19890249 — Biomarker: SLCO1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 19890249 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 19890249 — Biomarker: SLCO1B3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 11896506 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 58196 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 31324360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11509799 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23564914 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 25003117 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 25003117 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 1450626 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1450626 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 26549533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24672940 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17326083 — Biomarker: Ataxin-2
Type: Pharmacodynamic Biomarker (PDY)
Genes: ATXN2; ATX2; SCA2; TNRC13
Study 15147247 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28659181 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 28659181 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 17010568 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 17010568 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 17010568 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17010568 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17010568 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2195054 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 25092886 — Biomarker: Cyclin-dependent kinase inhibitor 1
Type: Safety Biomarker (SAF)
Genes: CDKN1A
Study 17692112 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 15351853 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15351853 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 21545991 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11348956 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2468896 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21292873 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 17541211 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 17541211 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11932280 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 11932280 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2550046 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 779587 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1578912 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3935869 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 3935869 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29560543 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24675955 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12383044 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10597550 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15215813 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15215813 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10974371 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8136092 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20526694 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7930659 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31350828 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15647189 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2090821 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 25761434 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24311451 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22445437 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 22445437 — Biomarker: PLG mRNA
Type: Predictive Biomarker (PRD)
Genes: PLG
Study 22445437 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15373008 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 2905879 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 17103080 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31354252 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 27140710 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27140710 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24438754 — Biomarker: HFE mRNA
Type: Predictive Biomarker (PRD)
Genes: HFE; HLAH
Study 24438754 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8771231 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20975106 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20735823 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 20735823 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 18370541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28606961 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28606961 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11668420 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 31607205 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31607205 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25539895 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11252881 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2551988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2551988 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2551988 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 2551988 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31175747 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21644085 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18355812 — Biomarker: UPK1B mRNA
Type: Predictive Biomarker (PRD)
Genes: UPK1B; TSPAN20
Study 18355812 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 23939394 — Biomarker: CPPED1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPPED1; CSTP1
Study 23939394 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 19491872 — Biomarker: LARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LARS1; KIAA1352; LARS
Study 10884455 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 9356091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21251896 — Biomarker: NEB mRNA
Type: Predictive Biomarker (PRD)
Genes: NEB
Study 21251896 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 9007717 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 1829918 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 28624486 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22562389 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10205747 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10205747 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 31470444 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 30223728 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28827258 — Biomarker: ACAD8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAD8; ARC42; IBD
Study 25618566 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 14644857 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10400415 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26388707 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 12435255 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12435255 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7373255 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22154243 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 22154243 — Biomarker: SERPINA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 22154243 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 22154243 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28096034 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 23135962 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 23135962 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23135962 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 23135962 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 17316373 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27412317 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 22657586 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20674983 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 20674983 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 29661486 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25042995 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21136039 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 9627377 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2778240 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 2778240 — Biomarker: RNASE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RNASE2; EDN; RNS2
Study 25039412 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25039412 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 25039412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21963936 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21963936 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31580506 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28073036 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21801246 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 21801246 — Biomarker: C-X-C motif chemokine 11
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 21801246 — Biomarker: CCL22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 21801246 — Biomarker: CCL18 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 21801246 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC