AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 2850904 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27661661 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 11026517 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 2110603 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29872922 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 14757848 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 25982053 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23690582 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21486960 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 12757345 — Biomarker: ADCY10 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADCY10; SAC
Study 10883664 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 9339548 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 30464407 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 20231857 — Biomarker: CHRNA7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA7; NACHRA7
Study 41550 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11372675 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 9505918 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3346087 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27444642 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 19317164 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19317164 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11707687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10892526 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 30024539 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30024539 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7614504 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16826097 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31439215 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 31439215 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26261033 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 26261033 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19249432 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 19249432 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7923660 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23999454 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17335542 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9215845 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21677073 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19699832 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19780243 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 26492775 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 26492775 — Biomarker: PEBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PEBP1; PBP; PEBP
Study 26492775 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22710021 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22710021 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22157475 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 9404828 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8121866 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29659529 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24177413 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2162239 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17765364 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 30607677 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 28376235 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 15281518 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11497396 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29733106 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 26541729 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 11736673 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27862898 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 26365758 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 31487739 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30640362 — Biomarker: Insulin receptor substrate 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IRS1
Study 21946897 — Biomarker: AZIN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AZIN1; OAZI; OAZIN
Study 9481276 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3552360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1266667 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31811645 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 10197673 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 7767539 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 7767539 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30076843 — Biomarker: HGD mRNA
Type: Predictive Biomarker (PRD)
Genes: HGD; HGO
Study 30076843 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 2108889 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 7001332 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 21367761 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 15126148 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 11217092 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 26996268 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 25758370 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 23628045 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 9597571 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 2890903 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 27737393 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 27737393 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19671656 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17472001 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12086555 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 19341122 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 11557681 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 11557681 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 3293875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3293875 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31518645 — Biomarker: ELN mRNA
Type: Predictive Biomarker (PRD)
Genes: ELN
Study 26601156 — Biomarker: IGHMBP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGHMBP2; SMBP2; SMUBP2
Study 8659761 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 8659761 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 3984771 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29343509 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24980662 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16042774 — Biomarker: SFTPB mRNA
Type: Predictive Biomarker (PRD)
Genes: SFTPB; SFTP3
Study 12443741 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8952600 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7852490 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30939085 — Biomarker: TKTL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TKTL1; TKR; TKT2
Study 21544313 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 21544313 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21544313 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 23122650 — Biomarker: CD52 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD52; CDW52; HE5
Study 7759273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22087680 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 848618 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28138158 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22112682 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9524901 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20104178 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16393321 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16393321 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 10497008 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21163116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31928690 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 31928690 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 31928690 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 26328497 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26328497 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 26328497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19825328 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 16715914 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16715914 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11465652 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11465652 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11465652 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8276045 — Biomarker: Glutamate dehydrogenase
Type: Safety Biomarker (SAF)
Study 2880692 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 12814161 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 8857916 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8857916 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 27766771 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17955358 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 11907945 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22491708 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12732859 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3904393 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28916603 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23940221 — Biomarker: RUNX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX1; AML1; CBFA2
Study 16424846 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 31346968 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 20951491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7917912 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7917912 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7917912 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 2844088 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24285491 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23645236 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23645236 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9356537 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9356537 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10321658 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10321658 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8755119 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 8755119 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1722793 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 7042699 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17230055 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 17230055 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 14715560 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30219460 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 15953681 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 7727330 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28483221 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 24832461 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24832461 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16739327 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8585042 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31859911 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 19358783 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19358783 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15207399 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8076623 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 1103606 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24504937 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22325984 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22325984 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22325984 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 10367822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24952577 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 24952577 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 24952577 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 24952577 — Biomarker: IDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH2
Study 22265810 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22265810 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16210721 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 23713218 — Biomarker: RRAD mRNA
Type: Predictive Biomarker (PRD)
Genes: RRAD; RAD
Study 23713218 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 8973788 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15801579 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8080348 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31142530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28839339 — Biomarker: SLC18A2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC18A2; SVMT; VMAT2
Study 17350367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7884017 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21279976 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14595564 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7685442 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 8365747 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 3060889 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10546924 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 28146065 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28819835 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 10617948 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 1512337 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1512337 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24889137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22863159 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12908893 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 2550646 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21939942 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 21939942 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 23660738 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22545106 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 22545106 — Biomarker: CASP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CASP4; ICH2
Study 22545106 — Biomarker: NAIP mRNA
Type: Predictive Biomarker (PRD)
Genes: NAIP; BIRC1
Study 22545106 — Biomarker: SORL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SORL1; C11orf32
Study 22545106 — Biomarker: ANAPC5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANAPC5; APC5
Study 22545106 — Biomarker: RHOB mRNA
Type: Predictive Biomarker (PRD)
Genes: RHOB; ARH6; ARHB
Study 2574728 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30689903 — Biomarker: E2F1 mRNA
Type: Predictive Biomarker (PRD)
Genes: E2F1; RBBP3
Study 19826110 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15467219 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 4018470 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28708766 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 23863960 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1750429 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1750429 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31778601 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 31778601 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 31778601 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 18756743 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8868980 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24802413 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 1665493 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30037426 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 27618825 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22334121 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 17932908 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15804733 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15804733 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15804733 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 15804733 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 7191779 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 30343508 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21833823 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1