AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 21844885 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21844885 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25645325 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22052313 — Biomarker: FGF7 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF7; KGF
Study 22052313 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 12231656 — Biomarker: VCP mRNA
Type: Predictive Biomarker (PRD)
Genes: VCP
Study 19390585 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11313175 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 3131387 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 17266689 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 15519189 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25753493 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25753493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17940987 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 31240310 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 22017530 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 22017530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24762259 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17949786 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 17949786 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 17949786 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17949786 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 7491373 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 8729093 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30882234 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 24582547 — Biomarker: CNR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNR1; CNR
Study 17494881 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17494881 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1092420 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 31425700 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31425700 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31425700 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 26728611 — Biomarker: RUNX1T1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study 22230651 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 7648705 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7648705 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24386952 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 18372700 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 565418 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29315160 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18440702 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 16188050 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 10435730 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 28639118 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19347033 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11052441 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 3164442 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 30262148 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12816263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19463517 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23214247 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 17515572 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 16135575 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10458713 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7541660 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31087723 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 31087723 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 28871440 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 26475215 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26475215 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26475215 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 14569279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2437789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1769635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31479003 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 26470711 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 16965680 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 8993241 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 31944310 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31944310 — Biomarker: Dermal blood flow
Type: Pharmacodynamic Biomarker (PDY)
Study 12792297 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1459154 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 1459154 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 6695853 — Biomarker: TNR mRNA
Type: Predictive Biomarker (PRD)
Genes: TNR
Study 29550383 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 29550383 — Biomarker: MAPK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK1; ERK2; PRKM1; PRKM2
Study 24625583 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20214755 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15814544 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12351331 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12351331 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9527962 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 9527962 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 9527962 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31837393 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 23835291 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16751820 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22110219 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11530275 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 18450829 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18450829 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16642224 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 16642224 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20172072 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 12150618 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 10541947 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 10541947 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7599840 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 340492 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 31566307 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15494915 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29154277 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 11994339 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9920063 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31812227 — Biomarker: COL1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL1A1
Study 31812227 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9817605 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8164053 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8164053 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 30196031 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1334284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30595357 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 28971986 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 22450257 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 21414045 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11485143 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8988911 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8988911 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2880903 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 22519907 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 22519907 — Biomarker: MAEA mRNA
Type: Predictive Biomarker (PRD)
Genes: MAEA; EMP; HLC10; PIG5
Study 16422854 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 16422854 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 324723 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30998643 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23585192 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23680059 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 21646925 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 16550731 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8981304 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8981304 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 8981304 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8981304 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29690924 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 29690924 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 26199465 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14604715 — Biomarker: DLK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DLK1; DLK
Study 28275132 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 28275132 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28275132 — Biomarker: INSR mRNA
Type: Predictive Biomarker (PRD)
Genes: INSR
Study 28275132 — Biomarker: NEGR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NEGR1; IGLON4; UNQ2433/PRO4993
Study 28275132 — Biomarker: POMC mRNA
Type: Predictive Biomarker (PRD)
Genes: POMC
Study 28275132 — Biomarker: ADIPOQ mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 28275132 — Biomarker: FAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FAT1; CDHF7; FAT
Study 28275132 — Biomarker: Fatty acid binding protein 1
Type: Safety Biomarker (SAF)
Genes: FABP1; FABPL
Study 28275132 — Biomarker: MC3R mRNA
Type: Predictive Biomarker (PRD)
Genes: MC3R
Study 25850750 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 23944767 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17223112 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17223112 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17223112 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17223112 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17106926 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23609838 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17060064 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17060064 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10936118 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 28158932 — Biomarker: FGR mRNA
Type: Predictive Biomarker (PRD)
Genes: FGR; SRC2
Study 26009829 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26009829 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 26009829 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26009829 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21846551 — Biomarker: KCNN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNN3; K3
Study 19308727 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19308727 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 11520725 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 28416171 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 27920516 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 20084314 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20084314 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11461949 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28219329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9597213 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29697274 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29697274 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22222177 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22222177 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26621361 — Biomarker: Mitochondrial frataxin
Type: Monitoring Biomarker (MOI)
Genes: FXN; FRDA; X25
Study 26621361 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12181183 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 1936476 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19699071 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15738285 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 29103664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8025983 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30773266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25371534 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20714991 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 31187203 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 23460709 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 15494637 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9741730 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 3198299 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 26637922 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24431895 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 3585679 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24739800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7841897 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 7841897 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 31899823 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31899823 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 31899823 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 28207497 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3534201 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31834099 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 24866870 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23139359 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23139359 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23139359 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20980412 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 1347763 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3896701 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 19920806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14583180 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14583180 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 21114605 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17599426 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9802965 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9802965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9802965 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 2681580 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30742386 — Biomarker: MALT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MALT1; MLT
Study 26279411 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24912462 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 20212016 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 20212016 — Biomarker: IGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF2; PP1446
Study 15811138 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11759109 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 31627728 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 23886531 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 23886531 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 23886531 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23886531 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 23886531 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1