AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 17304143 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 8620046 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 31842962 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31842962 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 19056078 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 17599420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17599420 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17599420 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15691617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8560527 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 6104973 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9597414 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3302342 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 29581161 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 21151978 — Biomarker: AQP5 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP5
Study 8596757 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 8582499 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 635480 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 31769596 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26404912 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 21495198 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study 21495198 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28965280 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23883378 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 21816062 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 8480900 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8480900 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12884458 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 13130389 — Biomarker: RRAD mRNA
Type: Predictive Biomarker (PRD)
Genes: RRAD; RAD
Study 13130389 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 13130389 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 10535718 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10535718 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1745340 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 21823969 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19152452 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19152452 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 19152452 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 2272708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24253250 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 24253250 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 24253250 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 24253250 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 24253250 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7924126 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 531993 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 31867908 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31867908 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19427810 — Biomarker: ASPSCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 15100514 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12714834 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27502307 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 16315242 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 31724191 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 29739385 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29931852 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 31482193 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25677355 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 15097245 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3122919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30516328 — Biomarker: MYCN mRNA
Type: Predictive Biomarker (PRD)
Genes: MYCN; BHLHE37; NMYC
Study 19383110 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 16772451 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 7957481 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 29728201 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18503806 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10893357 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 9042260 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27487437 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17396118 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7994791 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 2623077 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 24127622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19690081 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15526248 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11474540 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9506192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29501740 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27259675 — Biomarker: SRY mRNA
Type: Predictive Biomarker (PRD)
Genes: SRY; TDF
Study 20130841 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18070142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9235072 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9235072 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9235072 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31358540 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 31358540 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24532394 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 10804328 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 8778696 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 8065177 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28068165 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24243632 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 25534331 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25534331 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 25534331 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 1844749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29134635 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 1380411 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6873004 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 11952586 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22672107 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11151749 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 16024863 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 1837496 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6122652 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 24152604 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 21781598 — Biomarker: MIA mRNA
Type: Predictive Biomarker (PRD)
Genes: MIA
Study 11355930 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29673375 — Biomarker: SLC25A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A3; PHC; OK/SW-cl.48
Study 24810476 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1596903 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 25292404 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 24874483 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 24874483 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 20933301 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 20860505 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 28693985 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16014056 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 26466804 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26466804 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19644045 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27516541 — Biomarker: Succinate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: SDHD
Study 26543236 — Biomarker: CD2AP mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2AP
Study 26543236 — Biomarker: SORL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SORL1; C11orf32
Study 26543236 — Biomarker: FERMT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FERMT2; KIND2; MIG2; PLEKHC1
Study 26543236 — Biomarker: NECTIN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NECTIN2; HVEB; PRR2; PVRL2
Study 26543236 — Biomarker: TOMM40 mRNA
Type: Predictive Biomarker (PRD)
Genes: TOMM40; C19orf1; PEREC1; TOM40
Study 26543236 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 20705785 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12393590 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31978689 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31791637 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31791637 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25141360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19910177 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10900277 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 10900277 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8922661 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30847930 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 22318199 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 12975409 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9032849 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31142081 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2844546 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 31276454 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 7986390 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25924668 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8339215 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27637335 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 27637335 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 24378525 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 23043944 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 28882471 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 26133666 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12464983 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9475259 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9475259 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8529851 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8529851 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28841649 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28841649 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24235105 — Biomarker: COL1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL1A1
Study 18957613 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 18957613 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 9890856 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7783051 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 24094768 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24094768 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18179503 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 3901535 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 3901535 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 31615181 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28825508 — Biomarker: MEST mRNA
Type: Predictive Biomarker (PRD)
Genes: MEST; PEG1
Study 26066525 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23239968 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 17845256 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29447737 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 28668412 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8702050 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31026384 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25439136 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22739142 — Biomarker: SLC5A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A1; NAGT; SGLT1
Study 22739142 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 22739142 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 22739142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11187914 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 1283570 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1283570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28623849 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16921051 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 29317418 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7740021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26261640 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21436337 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 16646673 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16646673 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 8890945 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 27298569 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 27298569 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 27298569 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 25330631 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 18775608 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 12879220 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11694861 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3351300 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23307511 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21768905 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 27133033 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 27133033 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 22344575 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20620742 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 20620742 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 20620742 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7572771 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 64803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 64803 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30793440 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24462960 — Biomarker: RAPGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 16084882 — Biomarker: Insulin receptor substrate 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IRS1
Study 31605515 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 25844619 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19508653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25384603 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25384603 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 11212970 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28645713 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21612749 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 21612749 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 17925114 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 15089817 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1286640 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17845588 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12488405 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 9798529 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9798529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20537740 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 20537740 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 2423794 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24241787 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 21178084 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21178084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10634672 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30012431 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30012431 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21707679 — Biomarker: TLR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR7; UNQ248/PRO285
Study 14685870 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 2121104 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 26332798 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24796339 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 16566082 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10409573 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31643039 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 21719902 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 19944359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15155466 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)