AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 20716842 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 20716842 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15168720 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2780876 — Biomarker: CPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPZ
Study 31180512 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 25468945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21795553 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 21795553 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 11122838 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 11122838 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study 11122838 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11122838 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 28767552 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15343354 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10574584 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2156886 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 2156886 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 538766 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 27806969 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 19696660 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 10475182 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 6175803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21898040 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18822413 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17996517 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17996517 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17996517 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9614767 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 31250285 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 21241520 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 21241520 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 1740541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6377291 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24823671 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 11317199 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9344701 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 9344701 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 26773777 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25262522 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22475545 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 1823905 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1823905 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 1823905 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 6119182 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6119182 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22010913 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17414228 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11850771 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11850771 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11850771 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 11850771 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31443226 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17336181 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 15181565 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15181565 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11352127 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19231043 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 19231043 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 16768834 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 16768834 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16768834 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 7451917 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 31060602 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 31060602 — Biomarker: Tumor-infiltrating lymphocyte
Type: Predictive Biomarker (PRD)
Study 27794137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19293796 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 16674782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15560811 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 11742907 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 7973107 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 21247529 — Biomarker: CCR2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCR2; CMKBR2
Study 21247529 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21247529 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 2210808 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6151553 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31348732 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 20962312 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20962312 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20962312 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9933797 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9933797 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7398005 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29561188 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 29561188 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 29561188 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 29561188 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29561188 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17379124 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10640160 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2287705 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 19282782 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2656070 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 29547447 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19966072 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30325117 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30325117 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26381515 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 21670455 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27655039 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 21366847 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21069378 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3263243 — Biomarker: HDC mRNA
Type: Predictive Biomarker (PRD)
Genes: HDC
Study 3263243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29756459 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27506739 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25609264 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15685244 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10574413 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6834243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21166630 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18046975 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18046975 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9186075 — Biomarker: RAPGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 9186075 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2413300 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22399518 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 7906300 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25056158 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23263204 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19243712 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25149549 — Biomarker: IRF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRF4; MUM1
Study 25149549 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 19417195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7712526 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 30816665 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 30816665 — Biomarker: Mitochondrial membrane potential
Type: Pharmacodynamic Biomarker (PDY)
Study 19243324 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 19243324 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7977713 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 26130740 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23623280 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11912281 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2189448 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20039806 — Biomarker: IVNS1ABP mRNA
Type: Predictive Biomarker (PRD)
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068
Study 1733432 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 31730458 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 23787544 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 23787544 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 23787544 — Biomarker: Serum phosphate
Type: Surrogate Endpoint (SUR)
Study 16430539 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15577771 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30646291 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20152243 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20152243 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8775644 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8775644 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 29577324 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21935705 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 17438307 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17438307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9923581 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 25466664 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25466664 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17166332 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 3083718 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21604211 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1683336 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31862762 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31862762 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18458872 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 10155556 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 10155556 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 26252875 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 18623043 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9448150 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 328034 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 27381900 — Biomarker: PRKAG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKAG2
Study 27381900 — Biomarker: DCC mRNA
Type: Predictive Biomarker (PRD)
Genes: DCC; IGDCC1
Study 27381900 — Biomarker: EPHX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPHX2
Study 15840042 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10063787 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7586339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 375959 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30735751 — Biomarker: NFE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NFE2
Study 30735751 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 28795473 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 28795473 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 28795473 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 18156171 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9647412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29705218 — Biomarker: NANOS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS3; NOS3
Study 22492370 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9657623 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9657623 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31276312 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 31299617 — Biomarker: DMA mRNA
Type: Predictive Biomarker (PRD)
Genes: DMA; HLA-DMA; hCG_2001572
Study 25888263 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 22159929 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19806797 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16915750 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16915750 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19737963 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 15572534 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 12955551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29262859 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 21487851 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 16549964 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16549964 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 16549964 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 16549964 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12704305 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 10924705 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 24438512 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 22984506 — Biomarker: G6PC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: G6PC2; IGRP
Study 22984506 — Biomarker: GCKR mRNA
Type: Predictive Biomarker (PRD)
Genes: GCKR
Study 22984506 — Biomarker: ADCY5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADCY5
Study 19448234 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17092845 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 14653084 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 14653084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1908864 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1908864 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10613615 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22466329 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 16112720 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12161475 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 12161475 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7575695 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7575695 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 7575695 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7823520 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 28327893 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 28327893 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 24170102 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 14551147 — Biomarker: Vitamin K-dependent protein C
Type: Safety Biomarker (SAF)
Genes: PROC
Study 11216928 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24703167 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24703167 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24703167 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 24703167 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15131005 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15131005 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11588449 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 11588449 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11588449 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11588449 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 19770386 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 17803818 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26062880 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23385647 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21248328 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 17125603 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 14512778 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26077795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20969601 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 19004202 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3518384 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15930018 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 10965085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1996588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23272061 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 20386343 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8621010 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO