AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 16365183 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16365183 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 16365183 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12809966 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 24552888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24552888 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11916781 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11916781 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31262691 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 9373733 — Biomarker: SMARCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMARCA2; BAF190B; BRM; SNF2A; SNF2L2
Study 18481113 — Biomarker: ERCC8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC8; CKN1; CSA
Study 31091754 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 29300387 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 22234928 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22234928 — Biomarker: ZGPAT mRNA
Type: Predictive Biomarker (PRD)
Genes: ZGPAT; GPATC6; GPATCH6; KIAA1847; ZC3H9; ZC3HDC9; ZIP
Study 17875084 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10100994 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10100994 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 31532959 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31532959 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31076466 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 27618363 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 24089671 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11374602 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12427146 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27754427 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23488280 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 23488280 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23488280 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15516696 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15516696 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15516696 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21926427 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 21926427 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 20395869 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18315579 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10327193 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 31454045 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 19610264 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9520629 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 9520629 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18974448 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16550299 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11107867 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26140541 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26140541 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 26140541 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11525272 — Biomarker: SERPINA7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA7; TBG
Study 11525272 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18163011 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30382308 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27289174 — Biomarker: ARSA mRNA
Type: Predictive Biomarker (PRD)
Genes: ARSA
Study 24715381 — Biomarker: GPER1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPER1; CEPR; CMKRL2; DRY12; GPER; GPR30
Study 24715381 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24715381 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 16780390 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30853012 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24432670 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 24432670 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19638231 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12457031 — Biomarker: GRN mRNA
Type: Predictive Biomarker (PRD)
Genes: GRN
Study 12457031 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 22101218 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19037197 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 17151339 — Biomarker: Lysosomal alpha-glucosidase
Type: Safety Biomarker (SAF)
Genes: GAA
Study 15096906 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25854575 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25854575 — Biomarker: Th2 cell
Type: Safety Biomarker (SAF)
Study 25854575 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19583607 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19583607 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 27316539 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24600660 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 10096580 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21251162 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 21849264 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10928231 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 3908332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23587660 — Biomarker: ALDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH2; ALDM
Study 20456545 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 16581897 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11687774 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21280316 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15855323 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 1506600 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1506600 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29443767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9592327 — Biomarker: PLG mRNA
Type: Predictive Biomarker (PRD)
Genes: PLG
Study 9592327 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1649720 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3935120 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 29590326 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20437207 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20437207 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 15818745 — Biomarker: PTN mRNA
Type: Predictive Biomarker (PRD)
Genes: PTN; HBNF1; NEGF1
Study 29695772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25081390 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24091318 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 1427652 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 15803929 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31845065 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 26158178 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 23071718 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23071718 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9260729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16159849 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 3113957 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28933582 — Biomarker: TRPM8 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPM8; LTRPC6; TRPP8
Study 23525529 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 9316554 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9316554 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24401022 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 22874517 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20555135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10360660 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27064975 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22301477 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20584070 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20584070 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20584070 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17675590 — Biomarker: HINT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HINT1; HINT; PKCI1; PRKCNH1
Study 17675590 — Biomarker: FOXM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXM1; FKHL16; HFH11; MPP2; WIN
Study 12401533 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27423381 — Biomarker: miR-31
Type: Predictive Biomarker (PRD)
Genes: MIR31
Study 24977688 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22315014 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6790805 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 16680561 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 30934894 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 21809909 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10227413 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8707278 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 28570603 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25078946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22492501 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22492501 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17202798 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3535621 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27018532 — Biomarker: MAOA mRNA
Type: Predictive Biomarker (PRD)
Genes: MAOA
Study 20438514 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20438514 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18640108 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 12665540 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 19895590 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 12460865 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31775696 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 29246256 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29246256 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24825180 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17538639 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 17538639 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 22187510 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9886446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7792793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19463125 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29250545 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 29250545 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29250545 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 29250545 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29250545 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 8405631 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8405631 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2945332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23297844 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 16977507 — Biomarker: CXCL1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 14749454 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11705818 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 24947792 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24947792 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8310508 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28919708 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 28919708 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 28919708 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9549739 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3190999 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3190999 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22884136 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10215671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10215671 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30418227 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30165610 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26304967 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26304967 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23210563 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18453793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23253744 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16441950 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8764120 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 6282434 — Biomarker: MERTK mRNA
Type: Predictive Biomarker (PRD)
Genes: MERTK; MER
Study 30536595 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26574019 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26574019 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 15087598 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9003479 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 8622389 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8622389 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 31877631 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 25027821 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 20667082 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20667082 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17993041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15541408 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 8995749 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 27143690 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 27004344 — Biomarker: OAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OAS1; OIAS
Study 24078509 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21360491 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10970994 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 10970994 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26520396 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 19606690 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23604689 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 21476064 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 8017327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8017327 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30875390 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 30875390 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 20458210 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20458210 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 14559383 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10710555 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 10710555 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 9181268 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19590158 — Biomarker: LTB mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB; TNFC; TNFSF3
Study 16327030 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9784543 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9784543 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 9784543 — Biomarker: C4BPA mRNA
Type: Predictive Biomarker (PRD)
Genes: C4BPA; C4BP
Study 9784543 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7664863 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7664863 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 20386125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18436117 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 18436117 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16950753 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16950753 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12759881 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET