AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 11211198 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2663319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29129436 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8907587 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 28421384 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26031321 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 19176684 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19176684 — Biomarker: CCR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 21087399 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11453955 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11453955 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 16467096 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 16467096 — Biomarker: DHFR
Type: Safety Biomarker (SAF)
Genes: DHFR1
Study 27879499 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11795343 — Biomarker: ELF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELF3; ERT; ESX; JEN
Study 21605000 — Biomarker: FABP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FABP4
Study 16487434 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 16487434 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16487434 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27554378 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 22205309 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 22205309 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 10339734 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30885522 — Biomarker: miR-9
Type: Safety Biomarker (SAF)
Study 27636018 — Biomarker: TACR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TACR3; NK3R; TAC3R
Study 24831288 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15965309 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 15965309 — Biomarker: OMD mRNA
Type: Predictive Biomarker (PRD)
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 10822319 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10822319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15564986 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30173287 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30173287 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 26700585 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 26700585 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 26700585 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18556337 — Biomarker: PTPN22 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPN22; PTPN8
Study 18556337 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 18556337 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 18556337 — Biomarker: HLA-DQB1
Type: Safety Biomarker (SAF)
Genes: IDDM1; CELIAC1
Study 19687359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14759614 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11334895 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 9220209 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18845330 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11954942 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2209320 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24668358 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 20080287 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20080287 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23761378 — Biomarker: MAOA mRNA
Type: Predictive Biomarker (PRD)
Genes: MAOA
Study 18622251 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18622251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26682780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22846643 — Biomarker: EDA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDA; ED1; EDA2
Study 22846643 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19996308 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19996308 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19996308 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 31389599 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 28299764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23723317 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23723317 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17689948 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 11205921 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9698139 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7992446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7992446 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25599284 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 25599284 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30690825 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 22031518 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22031518 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 22031518 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 22031518 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19189517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8661977 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20438307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11910262 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 10327575 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 30376747 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 26664304 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19903982 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19903982 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12916666 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 27709360 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14607573 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 8018144 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10070170 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10070170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31517505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25622599 — Biomarker: ACY3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACY3; ASPA2
Study 25622599 — Biomarker: NPHS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NPHS1; NPHN
Study 25622599 — Biomarker: ALDH1A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH1A3; ALDH6
Study 25622599 — Biomarker: CLIC5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLIC5
Study 9286238 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31563820 — Biomarker: VARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VARS1; G7A; VARS; VARS2
Study 15974489 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 12324914 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 7862660 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6115104 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28415975 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23117205 — Biomarker: VASH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VASH1; KIAA1036; VASH
Study 15802775 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29108091 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24417761 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 24417761 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 24417761 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 22650767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12525719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8730607 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25979975 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 23417317 — Biomarker: SNAP25 mRNA
Type: Predictive Biomarker (PRD)
Genes: SNAP25; SNAP
Study 11548448 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7921924 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21531233 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11581068 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 7888231 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7888231 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 3345623 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23901664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23901664 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14660990 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 2663164 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18496196 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 18496196 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 9167099 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 27557561 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 27557561 — Biomarker: Osteopontin
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SPP1; BNSP; OPN; PSEC0156
Study 10418841 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2048514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24128075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18092260 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21916908 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19673711 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 9407512 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8100152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22976604 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 19470037 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10448289 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 373100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 373100 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 373100 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 373100 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 373100 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 373100 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 17543781 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15480108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26240957 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23396206 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17679043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17679043 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15060258 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 15060258 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17447116 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26423649 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19142802 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11257560 — Biomarker: RRAD mRNA
Type: Predictive Biomarker (PRD)
Genes: RRAD; RAD
Study 23719547 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19449238 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 8458113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28238045 — Biomarker: ACTG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACTG1; ACTG
Study 18554243 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 1392698 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 19648781 — Biomarker: CRABP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CRABP2
Study 19648781 — Biomarker: HBEGF mRNA
Type: Predictive Biomarker (PRD)
Genes: HBEGF; DTR; DTS; HEGFL
Study 11916359 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11916359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2904881 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9692538 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 25563714 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20199815 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 27817096 — Biomarker: NR3C1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR3C1; GRL
Study 11915588 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 1830287 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22093775 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 22093775 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10404423 — Biomarker: DMTN mRNA
Type: Predictive Biomarker (PRD)
Genes: DMTN; DMT; EPB49
Study 10404423 — Biomarker: TCHH mRNA
Type: Predictive Biomarker (PRD)
Genes: TCHH; THH; THL; TRHY
Study 26372211 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26372211 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28087807 — Biomarker: LAMB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMB2; LAMS
Study 19765449 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19765449 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19765449 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19765449 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 19765449 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14984856 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 28821686 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 28821686 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 28821686 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17106267 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 29429057 — Biomarker: PTN mRNA
Type: Predictive Biomarker (PRD)
Genes: PTN; HBNF1; NEGF1
Study 29429057 — Biomarker: ZDHHC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZDHHC2; REAM; REC; ZNF372
Study 24448757 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24448757 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 21900941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18954260 — Biomarker: PPARG mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARG; NR1C3
Study 18954260 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12488271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20088738 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20088738 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10225478 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10225478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 95728 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21256308 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7828793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30113526 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30113526 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25516338 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22951014 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22951014 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18256841 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18256841 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7491837 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 7491837 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 7491837 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28031424 — Biomarker: ALK
Type: Predictive Biomarker (PRD)
Genes: CD246; ALK1
Study 28031424 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 8960715 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26702991 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 12634965 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 1888238 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31892609 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25376940 — Biomarker: RAPGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 12860772 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 24374073 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 24374073 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23529990 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 12212923 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25481791 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 25481791 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 19004023 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 9589245 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9589245 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2644175 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30826452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17052581 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10381854 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10381854 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 10381854 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7037664 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28412650 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 28412650 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 25416687 — Biomarker: TEF mRNA
Type: Predictive Biomarker (PRD)
Genes: TEF; KIAA1655
Study 24554598 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24554598 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2