AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT01042158 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study NCT00172224 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01427218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02336815 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study NCT04128319 — Biomarker: CD7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD7
Study NCT03658928 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02879513 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study NCT00125970 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT05067881 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT02480088 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study NCT01466465 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT00153569 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00951379 — Biomarker: PPARG mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARG; NR1C3
Study NCT05940506 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study NCT01281163 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02877069 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT00664404 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study NCT00820144 — Biomarker: CTBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CTBS; CTB
Study NCT04101968 — Biomarker: Lysosomal acid glucosylceramidase
Type: Pharmacodynamic Biomarker (PDY)
Genes: GBA1; GBA; GC; GLUC
Study NCT04101968 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01144468 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02466516 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study NCT00390793 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT00390793 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT04780035 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT04261465 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT04261465 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study NCT00003868 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study NCT03134625 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT02731755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01635192 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study NCT01635192 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study NCT01288469 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01670968 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study NCT01670968 — Biomarker: SREBF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SREBF2; BHLHD2; SREBP2
Study NCT01689844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03231722 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05346978 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study NCT05346978 — Biomarker: Nqo1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: NQO1; DIA4; NMOR1
Study NCT05346978 — Biomarker: FOXO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXO1; FKHR; FOXO1A
Study NCT05346978 — Biomarker: FOXO3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXO3; FKHRL1; FOXO3A
Study NCT05346978 — Biomarker: FOXO6 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXO6
Study NCT03381820 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03966846 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00194974 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02654496 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study NCT00912574 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT03011749 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT00617331 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT01673516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02759913 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study NCT02275377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03000842 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00338650 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00265200 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study NCT01701960 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04169178 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT04169178 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study NCT00947453 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study NCT01865253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00329251 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT05188781 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00591500 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study NCT02995655 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study NCT02995655 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study NCT02995655 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study NCT02995655 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study NCT02995655 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study NCT02995655 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study NCT02995655 — Biomarker: TLR2
Type: Predictive Biomarker (PRD)
Genes: TIL4; CD282
Study NCT02093715 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study NCT03950778 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT02538276 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study NCT03264443 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00126646 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study NCT02324010 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03963336 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT01672879 — Biomarker: LOXL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LOXL2
Study NCT03926442 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03926442 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT03926442 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study NCT03051165 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03631953 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study NCT00675831 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study NCT00675831 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT02092116 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01309789 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study NCT04643847 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04643847 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00825695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03150147 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study NCT03150147 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study NCT00422643 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT00137995 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT03423433 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03279861 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00546754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05600335 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study NCT00005363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01833923 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study NCT01833923 — Biomarker: FLT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT4; VEGFR3
Study NCT03943290 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT03571360 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT01839526 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT02698813 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT00807937 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study NCT01823380 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT02235792 — Biomarker: High-frequency oscillations
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01840488 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study NCT01619293 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study NCT02502708 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study NCT04380467 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT03427307 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study NCT03608995 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT02540408 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study NCT02540408 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT03204565 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT01402479 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT04345510 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT02036307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03097770 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT00109642 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02789085 — Biomarker: PAG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAG1; CBP; PAG
Study NCT02001818 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT02001818 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT01767714 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01767714 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT03837990 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study NCT00860626 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT00613782 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study NCT00613782 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03262935 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00141349 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study NCT01634893 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study NCT01634893 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01634893 — Biomarker: RAF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAF1; RAF
Study NCT03336086 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study NCT01960244 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study NCT03109795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02811120 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study NCT02054039 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study NCT01831245 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study NCT01708798 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT00572104 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01266330 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01266330 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01001936 — Biomarker: SKI mRNA
Type: Predictive Biomarker (PRD)
Genes: SKI
Study NCT00152945 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT02084849 — Biomarker: PRKD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKD1; PKD; PKD1; PRKCM
Study NCT02191319 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04554732 — Biomarker: FGF7 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF7; KGF
Study NCT01610297 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study NCT02639910 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study NCT00204113 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study NCT03278587 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT03549338 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03549338 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT04593251 — Biomarker: CALY mRNA
Type: Predictive Biomarker (PRD)
Genes: CALY; DRD1IP
Study NCT01020045 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study NCT01765231 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT02191098 — Biomarker: Undetectable plasma HIV RNA
Type: Surrogate Endpoint (SUR)
Study NCT00921115 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT02290613 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT03433586 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study NCT02270658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03599518 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03884153 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00951704 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00422006 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study NCT00068601 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT00068601 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT00532129 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT01625234 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT03761472 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT02948764 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study NCT03372473 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study NCT05798273 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02035670 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03373708 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT03373708 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03373708 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study NCT02880111 — Biomarker: DMBT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DMBT1; GP340
Study NCT03069313 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT04244240 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01340222 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study NCT01340222 — Biomarker: CCR2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCR2; CMKBR2
Study NCT01340222 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT01340222 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study NCT00876863 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study NCT04113798 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT04113798 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT00957242 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT02701036 — Biomarker: ZFYVE9 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZFYVE9; MADHIP; SARA; SMADIP
Study NCT01519037 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study NCT00847834 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00737724 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT02348957 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT02348957 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT00338572 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00338572 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00338572 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00338572 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT00338572 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study NCT03527160 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study NCT03527160 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT03909412 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01583114 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT03197610 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study NCT00040313 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03133234 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03133234 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03827369 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04297371 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT04544254 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT00358033 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03584347 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT01599104 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06224946 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT06224946 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT03050814 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study NCT02438904 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT01239758 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT01239758 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study NCT04364139 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01294215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01005641 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01005641 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT01933802 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT01331681 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF