AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 10232563 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 28541802 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 15502736 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15502736 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 21904088 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 19121433 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 27457511 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 21813223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2758453 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28851784 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21062790 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17096501 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 3514202 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31394948 — Biomarker: PRPH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRPH2; PRPH; RDS; TSPAN22
Study 24204067 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24204067 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24204067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18640826 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16612448 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12531630 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study 10951629 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 1426513 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 28691417 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 19620517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8360732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22210925 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 21351255 — Biomarker: EXOG mRNA
Type: Predictive Biomarker (PRD)
Genes: EXOG; ENDOGL1; ENDOGL2; ENGL
Study 21351255 — Biomarker: MT1G mRNA
Type: Predictive Biomarker (PRD)
Genes: MT1G; MT1K; MT1M
Study 16286438 — Biomarker: Amyloid beta peptide (1-40)
Type: Pharmacodynamic Biomarker (PDY)
Genes: APP; A4; AD1
Study 8043977 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 8043977 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8043977 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8043977 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 29174310 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 11057854 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23439301 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 11262572 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8204876 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 30350337 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23681683 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8860730 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31753900 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9935018 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 365537 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29463627 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28078857 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28078857 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 27871846 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 27871846 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 27871846 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27021566 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17552048 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 17552048 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 17552048 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9611008 — Biomarker: POMP mRNA
Type: Predictive Biomarker (PRD)
Genes: POMP; C13orf12; UMP1; HSPC014; HSPC036; PNAS-110
Study 25887378 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9702436 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 31102331 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 11289700 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 11289700 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 29289531 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 26551986 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26381715 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 16627794 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14596362 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6540581 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6540581 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26012640 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 26012640 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15093878 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11251731 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16446318 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12582945 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 30267357 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 16351593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21062778 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 18430053 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18430053 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18430053 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15030296 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15030296 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1586398 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24500432 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 24500432 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 27803006 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 27803006 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27803006 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19670959 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 15121119 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 3473681 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 23344474 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9802618 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 18637053 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 2665546 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25675557 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 22471559 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22471559 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 14512295 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11673750 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9826861 — Biomarker: DSP mRNA
Type: Predictive Biomarker (PRD)
Genes: DSP
Study 25185971 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 21852581 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21852581 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 21852581 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16713439 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 16713439 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2202853 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6104255 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6104255 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 17868728 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3814462 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9578184 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 9578184 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 11092233 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1334101 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 1334101 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6418295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28646860 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 19483295 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 16920648 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10639191 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 31837959 — Biomarker: Aurora kinase A
Type: Predictive Biomarker (PRD)
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 21389855 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 14748999 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8973979 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 8973979 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 24375082 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC
Study 18331610 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 8308962 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26209642 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 26209642 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19139031 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 17713165 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 15126801 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21375019 — Biomarker: SP8 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP8
Study 21375019 — Biomarker: SP9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP9
Study 1299500 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 6432001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27651882 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 19123156 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 15970715 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15970715 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7895538 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 27515478 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 23582934 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 11739137 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 8424427 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3687269 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28735368 — Biomarker: TRIM32 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM32; HT2A
Study 10037314 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10037314 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 48835 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31139687 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 24187864 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 3556192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29239148 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 27110823 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 23687780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9228496 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 15097237 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29494423 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 29494423 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 27016718 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 23852294 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9273207 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1518258 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 30176897 — Biomarker: CPQ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPQ; LCH1; PGCP
Study 18580611 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18580611 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9345406 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 21593784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18820280 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 18820280 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18820280 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8796137 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8796137 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 22137494 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 8526788 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31685553 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 31685553 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 3653758 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 31957889 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 29721623 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22251828 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 12850874 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30580469 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22516265 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 12417543 — Biomarker: NE
Type: Predictive Biomarker (PRD)
Study 12417543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28891024 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study 28891024 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 28891024 — Biomarker: ACLY mRNA
Type: Predictive Biomarker (PRD)
Genes: ACLY
Study 28891024 — Biomarker: SLC5A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A1; NAGT; SGLT1
Study 28891024 — Biomarker: SLC2A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A2; GLUT2
Study 27228369 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 28073198 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 24351403 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24351403 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 24351403 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18249325 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 18249325 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18249325 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 18249325 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 18249325 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 12756219 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19889807 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19889807 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16952782 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16952782 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8861666 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 25475196 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23268365 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19931080 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 19931080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19931080 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12401731 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12401731 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29273027 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29273027 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19448381 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 17854445 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 2142576 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 489921 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 28090798 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 20945090 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 19756164 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14667741 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 10826311 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24732441 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 20074348 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18175773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28039406 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 28039406 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 8728346 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1996576 — Biomarker: RAPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPH1; ALS2CR18; ALS2CR9; KIAA1681; LPD; PREL2; RMO1
Study 10202876 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 10202876 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 393356 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22092168 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 22092168 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18825612 — Biomarker: UCP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP3; SLC25A9
Study 18825612 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18825612 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11587994 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 3294067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)