AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31369355 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31369355 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24858257 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 24858257 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 11158042 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11158042 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11158042 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11158042 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9764965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15531006 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29091527 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23683266 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23683266 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7425697 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 27375714 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26242117 — Biomarker: BSG mRNA
Type: Predictive Biomarker (PRD)
Genes: BSG; UNQ6505/PRO21383
Study 26242117 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19302901 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 15449752 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 15449752 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15449752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 189333 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19114797 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 11739308 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1565758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16036492 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30614616 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30614616 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12192890 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 7898521 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 2716162 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28182127 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22145448 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19451819 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12637461 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 8898515 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 1381024 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6387631 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 30786187 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7786657 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9072885 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21438412 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21438412 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12107665 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26124797 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26124797 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23791619 — Biomarker: CXCR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR2; IL8RB
Study 16169314 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10577444 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11397963 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11397963 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7904930 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 20169461 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15321934 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 20563833 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 8959115 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 28982882 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11165422 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 2892430 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2892430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30121291 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 30121291 — Biomarker: CCL18 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 30121291 — Biomarker: CCL22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 30121291 — Biomarker: CCL20 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL20; LARC; MIP3A; SCYA20
Study 30121291 — Biomarker: DEFB4A mRNA
Type: Predictive Biomarker (PRD)
Genes: DEFB4A; DEFB102; DEFB2; DEFB4; DEFB4B
Study 16678543 — Biomarker: PTGS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGS1; COX1
Study 16678543 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 15217657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16598777 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1346172 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 12611766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8732695 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 27502850 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 20697803 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18318083 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 25645978 — Biomarker: CYBB mRNA
Type: Predictive Biomarker (PRD)
Genes: CYBB; NOX2
Study 24685998 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30217513 — Biomarker: CGN mRNA
Type: Predictive Biomarker (PRD)
Genes: CGN; KIAA1319
Study 24446238 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 24446238 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12419087 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31655788 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 27997064 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21054770 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27117004 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 19865105 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 19865105 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31388185 — Biomarker: POLE mRNA
Type: Predictive Biomarker (PRD)
Genes: POLE; POLE1
Study 31388185 — Biomarker: CD8A mRNA
Type: Predictive Biomarker (PRD)
Genes: CD8A; MAL
Study 24499136 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 20709302 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17547799 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 16362147 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26360825 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20878389 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17182805 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1583252 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 18090458 — Biomarker: ELOVL6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELOVL6; FACE; LCE
Study 31874050 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29891272 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 23299716 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 18283386 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 16093267 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 16093267 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8793613 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16105050 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15157949 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9478090 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24597534 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16973692 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 556111 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19447369 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 19447369 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 2531184 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2531184 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 2531184 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31556131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23845522 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29133549 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 25105458 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 18714238 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18714238 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8410924 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3011885 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29029053 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 23648372 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11712308 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 31594062 — Biomarker: TAL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAL1; BHLHA17; SCL; TCL5
Study 31594062 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29451912 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 29451912 — Biomarker: Cyclin-dependent kinase inhibitor 1
Type: Safety Biomarker (SAF)
Genes: CDKN1A
Study 29451912 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 29451912 — Biomarker: E2F1 mRNA
Type: Predictive Biomarker (PRD)
Genes: E2F1; RBBP3
Study 29451912 — Biomarker: MDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM2
Study 29451912 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 29451912 — Biomarker: Retinoblastoma-associated protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: RB1
Study 29451912 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 29451912 — Biomarker: PDGFRA mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 29451912 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 22252353 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 11872654 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 11872654 — Biomarker: Insulin receptor substrate 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IRS1
Study 10195381 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 10195381 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25888343 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28450193 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 28450193 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24898537 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30265045 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 26885819 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 12131074 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7573997 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15824055 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10220741 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 110211 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 27328681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22340793 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study 22340793 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 15716195 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 31073737 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 22260080 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16891677 — Biomarker: CFL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CFL1; CFL
Study 6487947 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26751765 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 23585666 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 20937051 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18384418 — Biomarker: CACNA1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CACNA1A; CACH4; CACN3; CACNL1A4
Study 18384418 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 16730418 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14680611 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 14680611 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26332311 — Biomarker: ACAD8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAD8; ARC42; IBD
Study 20579405 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16182039 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23039030 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23039030 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21142812 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21142812 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21142812 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12953850 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12953850 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10703679 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7870914 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29574518 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18356403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2056262 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2056262 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 15175435 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11753186 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11753186 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 29471124 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23147684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24959618 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15832830 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12875727 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 12875727 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2145212 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 30755574 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22814367 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22814367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22814367 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10446945 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10446945 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28082335 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25474535 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 3092610 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29622823 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29622823 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3978827 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 26339899 — Biomarker: OPRM1
Type: Safety Biomarker (SAF)
Genes: MOR1; MOP
Study 17083352 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17083352 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 14660453 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 14660453 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7938556 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3130175 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11296186 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26029985 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15024300 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15024300 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11122839 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 11122839 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 22889406 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22889406 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22889406 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 22889406 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 8872133 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1518317 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22784777 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 7935654 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16003735 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 28832393 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 18208600 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 10883868 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 1580284 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1580284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29340321 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 29340321 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 24127838 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 8582783 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17489733 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 25159300 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21771722 — Biomarker: CYP19A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 16371604 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 2225558 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 25762165 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15270367 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15270367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27444039 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 18523316 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18523316 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12849766 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 9509074 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL