AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24628577 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21848848 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 19647866 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15223897 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11880014 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 2226911 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2226911 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30001712 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 23319466 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 12042618 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 22729966 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16860174 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3063798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31053766 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 31053766 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 18425402 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 10792338 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 26658900 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26658900 — Biomarker: NR1H2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1H2; LXRB; NER; UNR
Study 26658900 — Biomarker: CXCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR1; CMKAR1; IL8RA
Study 26658900 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15080356 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16949487 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10972169 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 25305179 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 22492374 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 20388073 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19954060 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7681510 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7681510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31721089 — Biomarker: IDE mRNA
Type: Predictive Biomarker (PRD)
Genes: IDE
Study 26201085 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26201085 — Biomarker: Complement C4
Type: Monitoring Biomarker (MOI)
Study 26201085 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26201085 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26201085 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 26201085 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 20225994 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 27859478 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 26255012 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12577391 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 2439781 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21169260 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 26869678 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17825197 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19151286 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19151286 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 19151286 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11923552 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 175146 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 17988379 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17988379 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17988379 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17988379 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28727955 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30897303 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24736801 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 22304968 — Biomarker: PICALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PICALM; CALM
Study 22304968 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 25716777 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25716777 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 25716777 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25716777 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 23475700 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14633525 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 27058233 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 17882870 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10451015 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 31937528 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26251920 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26251920 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26251920 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26251920 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 23433768 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 23433768 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6611576 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 17696230 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 27095187 — Biomarker: PPP1R13L mRNA
Type: Predictive Biomarker (PRD)
Genes: PPP1R13L; IASPP; NKIP1; PPP1R13BL; RAI
Study 19515739 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19515739 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25287156 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20063135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22868657 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10845879 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 10845879 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10845879 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 26238113 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26238113 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 26238113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18837771 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18837771 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17076223 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28678111 — Biomarker: SLC4A7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC4A7; BT; NBC2; NBC2B; NBC3; NBCn1; SBC2; SLC4A6
Study 16649881 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 10895397 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 1378685 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31752756 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 24889731 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 9928856 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 31385880 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31385880 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 23760160 — Biomarker: Mitochondrial membrane potential
Type: Pharmacodynamic Biomarker (PDY)
Study 9254071 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9254071 — Biomarker: EVA1A mRNA
Type: Predictive Biomarker (PRD)
Genes: EVA1A; FAM176A; TMEM166; SP24
Study 31552541 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 27565230 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 27565230 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25473210 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19337387 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 3361170 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 3361170 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 22616770 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 12665684 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11024374 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 25550188 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 19692688 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 3912335 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17159456 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 17159456 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 11487379 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11487379 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 9763328 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 21820084 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18075221 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9150779 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3323648 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29473353 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 29473353 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 29477262 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 29477262 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 29477262 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 27393697 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 20420943 — Biomarker: Osteopontin
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SPP1; BNSP; OPN; PSEC0156
Study 26265727 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22522786 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11861264 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 30540657 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30540657 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 30540657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24643755 — Biomarker: UCP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP2; SLC25A8
Study 24643755 — Biomarker: UCP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP3; SLC25A9
Study 24643755 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 24643755 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23219310 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 9418642 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 28029114 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25011384 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19190821 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 15158621 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 15158621 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 15158621 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 15158621 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 15158621 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27670154 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 23701202 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 16542207 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study 11180036 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9597123 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8199179 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2452393 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 19615804 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11741827 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11741827 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26561628 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1699088 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31896121 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 17179108 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11076325 — Biomarker: NBN mRNA
Type: Predictive Biomarker (PRD)
Genes: NBN; NBS; NBS1; P95
Study 3908782 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 31941260 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31941260 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18479353 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 8949315 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31780765 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 31780765 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 26350480 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21823222 — Biomarker: Nicotinamide phosphoribosyltransferase
Type: Safety Biomarker (SAF)
Genes: NAMPT; PBEF; PBEF1
Study 27310328 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 22653713 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11318020 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11318020 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 8487059 — Biomarker: SRM mRNA
Type: Predictive Biomarker (PRD)
Genes: SRM; SPS1; SRML1
Study 3122629 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14679493 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 3396546 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 19110600 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8347899 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28988341 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 28988341 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27529317 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22154769 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 17682988 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24232701 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7774989 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19157547 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 17086362 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15150954 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28237426 — Biomarker: RPE65 mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE65
Study 25812482 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 29725975 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27430216 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10660004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1353642 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6650492 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 22917555 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29197871 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 29197871 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23589672 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9623424 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30394153 — Biomarker: AFM mRNA
Type: Predictive Biomarker (PRD)
Genes: AFM; ALB2; ALBA
Study 21458598 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10893367 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 24725763 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22340556 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 20930431 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22106246 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10338322 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 10338322 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7796076 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 2326330 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16924006 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 11057790 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 31490424 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 20588058 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16887213 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10594527 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 10594527 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 10594527 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 2085344 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 17453591 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15212115 — Biomarker: Ataxin-2
Type: Pharmacodynamic Biomarker (PDY)
Genes: ATXN2; ATX2; SCA2; TNRC13
Study 10857213 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 9088884 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 3899418 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29587770 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29587770 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29587770 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24315979 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 2526824 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28407722 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24684808 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 31468214 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28831954 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 16313817 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 6184562 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6184562 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17529914 — Biomarker: EDA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDA; ED1; EDA2
Study 17529914 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3317338 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28399981 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 20824894 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT