AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 14734123 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 14734123 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11452711 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11452711 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29389738 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29389738 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29389738 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 29389738 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29389738 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29389738 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 27437724 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 25743829 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 1335012 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15813810 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 15813810 — Biomarker: GNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNL3; E2IG3; NS
Study 15813810 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 12154417 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 11800061 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17304419 — Biomarker: SLC22A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A4; ETT; OCTN1; UT2H
Study 11140366 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 30646140 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 27282261 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 18815815 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 26912554 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10051494 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 2147377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28574779 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 25651246 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 24280470 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21453540 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9618753 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 9098473 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 3741249 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16629292 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24597619 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 18842771 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 16102616 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 11847518 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 8908381 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8908381 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 31969184 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16236038 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 10431944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2152233 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26245756 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8318561 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 28757912 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28757912 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 24162448 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 29457221 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22624993 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 16841679 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 10983905 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 3855724 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 16338260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7662241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15589004 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29231587 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 25208859 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 17070426 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8941101 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29319935 — Biomarker: Beta-secretase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: BACE1; BACE; KIAA1149
Study 12110497 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12110497 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10220012 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 26968101 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11895146 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11895146 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11895146 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8040669 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 22381427 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 17667193 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 1253812 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31533195 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29042490 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26252642 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26252642 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26252642 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22071711 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19893201 — Biomarker: GLS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS2; GA
Study 17111195 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 17111195 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 17111195 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 17111195 — Biomarker: ADGRE5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADGRE5; CD97
Study 17111195 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17111195 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 15317270 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 15317270 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30021580 — Biomarker: DCC mRNA
Type: Predictive Biomarker (PRD)
Genes: DCC; IGDCC1
Study 30021580 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 10222388 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 31440235 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31440235 — Biomarker: IRF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRF5
Study 31440235 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 25902655 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19675482 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11304102 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11304102 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29655928 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11834946 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 21211865 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16083782 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 28027282 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 28027282 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28027282 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31035775 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24472799 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29412045 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 23204156 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 23204156 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 23204156 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 20954968 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 18408362 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 12414883 — Biomarker: NE
Type: Predictive Biomarker (PRD)
Study 31332099 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 23835365 — Biomarker: CXADR mRNA
Type: Predictive Biomarker (PRD)
Genes: CXADR; CAR
Study 18199798 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18199798 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 10745279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17174559 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12483170 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9665357 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7647542 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 7647542 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27646937 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27646937 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 27941730 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 19173749 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 19173749 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 15479125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7588920 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2285255 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31122901 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 31122901 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 28538025 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20493642 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9243350 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 24199224 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 17022368 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 6124083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28617530 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21292169 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 9517598 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3050006 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 1545086 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26944728 — Biomarker: LARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LARS1; KIAA1352; LARS
Study 15781539 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28203695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23683444 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12761586 — Biomarker: DNER mRNA
Type: Predictive Biomarker (PRD)
Genes: DNER; BET; UNQ262/PRO299
Study 7519691 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7519691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7957523 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7957523 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 7957523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21545947 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19466436 — Biomarker: Lysosomal acid glucosylceramidase
Type: Pharmacodynamic Biomarker (PDY)
Genes: GBA1; GBA; GC; GLUC
Study 19466436 — Biomarker: SPTLC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPTLC2; KIAA0526; LCB2
Study 19466436 — Biomarker: SMPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMPD1; ASM
Study 19466436 — Biomarker: ALOX12B mRNA
Type: Predictive Biomarker (PRD)
Genes: ALOX12B
Study 19466436 — Biomarker: ALOXE3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALOXE3
Study 19466436 — Biomarker: HMGCS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HMGCS1; HMGCS
Study 19466436 — Biomarker: PPARG mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARG; NR1C3
Study 19466436 — Biomarker: ACACB mRNA
Type: Predictive Biomarker (PRD)
Genes: ACACB; ACC2; ACCB
Study 19466436 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31894491 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25643895 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19015590 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31236143 — Biomarker: Urokinase plasminogen activator surface receptor
Type: Monitoring Biomarker (MOI)
Genes: PLAUR; MO3; UPAR
Study 22164810 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22302034 — Biomarker: Amyloid beta peptide (1-40)
Type: Pharmacodynamic Biomarker (PDY)
Genes: APP; A4; AD1
Study 1383592 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25174283 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22815653 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16103233 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16103233 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16103233 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16103233 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11967028 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21152040 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 24304099 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 17981316 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9665010 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8297546 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20098455 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 18003764 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15182393 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 22828553 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20819493 — Biomarker: NDP mRNA
Type: Predictive Biomarker (PRD)
Genes: NDP; EVR2
Study 2782734 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31169883 — Biomarker: CYP11B1 mRNA
Type: Safety Biomarker (SAF)
Genes: CYP11B1; S11BH
Study 31169883 — Biomarker: CYP17A1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CYP17A1; CYP17; S17AH
Study 31169883 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 31169883 — Biomarker: HSD17B12 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSD17B12; SDR12C1
Study 31169883 — Biomarker: WNT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: WNT4; UNQ426/PRO864
Study 23139262 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 18438705 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18438705 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 14679377 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14679377 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3285829 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 9382659 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8322563 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2868656 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2868656 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23301475 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 20506356 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 12621135 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 12621135 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26647926 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 15484172 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15484172 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8996166 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 8996166 — Biomarker: Dihydrothymine dehydrogenase
Type: Safety Biomarker (SAF)
Genes: DPYD
Study 29053933 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 29053933 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 29053933 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15699766 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6354932 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20830534 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 12469360 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 2594822 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17462541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16496609 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16496609 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 16496609 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 16496609 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 2183868 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26044442 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7011964 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16222404 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7589028 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 28202004 — Biomarker: CHEK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHEK1; CHK1
Study 15252191 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15252191 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 10758467 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8649652 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 6731015 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 31081924 — Biomarker: F10 mRNA
Type: Predictive Biomarker (PRD)
Genes: F10
Study 28462519 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23801842 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12180581 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7741773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1970370 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1970370 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30256671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24472614 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 18087004 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 11585312 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 31856576 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4