AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 20586923 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 7614641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19433757 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19433757 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19433757 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 14651947 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29525970 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24527578 — Biomarker: RAPGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 22182482 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22182482 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19933991 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26123142 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 20051465 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2970360 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 2970360 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 9267668 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 8488991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29475197 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 29475197 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29475197 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 27619632 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23134522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19026302 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19026302 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19026302 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14506330 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 14506330 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2650581 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2650581 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10654038 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 8345004 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 22658359 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22658359 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18681789 — Biomarker: Serine/threonine-protein kinase STK11
Type: Safety Biomarker (SAF)
Genes: STK11
Study 11927515 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11927515 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26769332 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 26769332 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 17618427 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 28006991 — Biomarker: Insulin receptor substrate 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IRS1
Study 15560702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27687613 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12113286 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27128606 — Biomarker: MBTPS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBTPS1; KIAA0091; S1P; SKI1
Study 27128606 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30784673 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 30784673 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 30784673 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 15184278 — Biomarker: NE
Type: Predictive Biomarker (PRD)
Study 15184278 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7211892 — Biomarker: MPG mRNA
Type: Predictive Biomarker (PRD)
Genes: MPG; AAG; ANPG; MID1
Study 26905220 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19618317 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11978136 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 18089983 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1677015 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2893636 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17699358 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 7755647 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7755647 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9931170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17671281 — Biomarker: STAR mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAR; STARD1
Study 1521362 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30450551 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 30450551 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30450551 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 3731680 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 27821598 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19587388 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10347337 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10347337 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15082469 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 15082469 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9690714 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31916662 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 28057872 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 28057872 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 28057872 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28057872 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 25534580 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12654706 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10780101 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25943368 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 18246677 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 2744062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31207126 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26022912 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23860021 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23860021 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23860021 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20112482 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 15186658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15186658 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26966058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19926782 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 19926782 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 19926782 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 19926782 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17351377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11846190 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 7562885 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 31393397 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 16470128 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29722833 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 27168163 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 18202561 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 18202561 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 18202561 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17628127 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30195946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29659178 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 24930044 — Biomarker: CX3CL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CX3CL1; FKN; NTT; SCYD1; A-152E5.2
Study 24930044 — Biomarker: CX3CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CX3CR1; CMKBRL1; GPR13
Study 7915963 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 18083636 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 12767649 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 10920611 — Biomarker: NFIC mRNA
Type: Predictive Biomarker (PRD)
Genes: NFIC; NFI
Study 10920611 — Biomarker: EHF mRNA
Type: Predictive Biomarker (PRD)
Genes: EHF; ESE3; ESE3B; ESEJ
Study 8751518 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23571688 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3155318 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30137607 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 30137607 — Biomarker: HTR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2A; HTR2
Study 30137607 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 23849501 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 22416440 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22416440 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16735696 — Biomarker: CD81 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD81; TAPA1; TSPAN28
Study 16735696 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16735696 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 10128359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23899039 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3749007 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3749007 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3749007 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25847979 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19773098 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 8482933 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30528676 — Biomarker: Fatty acid amide hydrolase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: FAAH; FAAH1
Study 28049937 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28049937 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 10758454 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29668978 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29668978 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26663715 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24559218 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 11796444 — Biomarker: ARID3B mRNA
Type: Predictive Biomarker (PRD)
Genes: ARID3B; BDP; DRIL2
Study 29287749 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 2566825 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 25274038 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 25274038 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 25274038 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 24144057 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 24144057 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 24144057 — Biomarker: SOD2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SOD2
Study 24144057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24144057 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 9570378 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 8447244 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3533265 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18772860 — Biomarker: DDAH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDAH2; DDAH; G6A; NG30
Study 25314578 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21667042 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28521867 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 28521867 — Biomarker: PRKD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKD1; PKD; PKD1; PRKCM
Study 28521867 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study 24406481 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21971125 — Biomarker: SFPQ mRNA
Type: Predictive Biomarker (PRD)
Genes: SFPQ; PSF
Study 19582880 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 19582880 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 7416061 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24586897 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 11932294 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 20135885 — Biomarker: CPD mRNA
Type: Predictive Biomarker (PRD)
Genes: CPD
Study 15144469 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23793449 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11751182 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 21592480 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11078237 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22271411 — Biomarker: KLB mRNA
Type: Predictive Biomarker (PRD)
Genes: KLB
Study 22271411 — Biomarker: FGFR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR4; JTK2; TKF
Study 22271411 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study 18925641 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31079535 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25040503 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3415207 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27703346 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27703346 — Biomarker: Mothers against decapentaplegic homolog 2
Type: Predictive Biomarker (PRD)
Genes: SMAD2; MADH2; MADR2
Study 25215556 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 25215556 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 20031551 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 20031551 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 20031551 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31606860 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31606860 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 29368594 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22386229 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 16350679 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16350679 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10232529 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 1926985 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1926985 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29341471 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12472369 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7604808 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7604808 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26802969 — Biomarker: Platelet-derived growth factor B
Type: Pharmacodynamic Biomarker (PDY)
Genes: PDGFB; PDGF2; SIS
Study 12016098 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 27632069 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 17456571 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17456571 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20846920 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20846920 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 20846920 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 30290775 — Biomarker: TMEM37 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMEM37; PR
Study 24299021 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 14509153 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14509153 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10204589 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2671247 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24254557 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 19091331 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 31682461 — Biomarker: APOA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOA1
Study 9219047 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30047584 — Biomarker: Dihydrothymine dehydrogenase
Type: Safety Biomarker (SAF)
Genes: DPYD
Study 12114432 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 7850941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25500935 — Biomarker: PER1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PER1; KIAA0482; PER; RIGUI
Study 25500935 — Biomarker: PER2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PER2; KIAA0347
Study 25500935 — Biomarker: BMAL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BMAL1; ARNTL; BHLHE5; MOP3; PASD3
Study 22890582 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 26798983 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 17903073 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17903073 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16131023 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26721648 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 26721648 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 23173697 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 20438867 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12574218 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31964380 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 19299790 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19299790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10357955 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG