AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 26481764 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 12097688 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12097688 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12097688 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10424318 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24428733 — Biomarker: CHRNA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA4; NACRA4
Study 17636280 — Biomarker: TMEM37 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMEM37; PR
Study 17636280 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 14657616 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 3401284 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 29165355 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 29165355 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 29165355 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29165355 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 24304733 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16983180 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 23546172 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 19608589 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22188532 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1899365 — Biomarker: TIE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TIE1; TIE
Study 31051504 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 26802147 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20236788 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 20236788 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20236788 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17639302 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 9649710 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 9649710 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 28836279 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 24163397 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15450559 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9832480 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9832480 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31642586 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31642586 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31272568 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 31272568 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25681059 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 25681059 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 25681059 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8148217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2659002 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 23213101 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19887477 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 19887477 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 19887477 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19887477 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 19887477 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 11421999 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8482046 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20171424 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18394874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22729307 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 15875154 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 15875154 — Biomarker: PLTP mRNA
Type: Predictive Biomarker (PRD)
Genes: PLTP
Study 12519867 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12519867 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31928076 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 31928076 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 31928076 — Biomarker: IL16 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL16
Study 31928076 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 31928076 — Biomarker: IL16
Type: Safety Biomarker (SAF)
Genes: LCF; IL-16; prIL-16; HsT19289; FLJ42735; FLJ16806
Study 30630783 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 6410898 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29871849 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 9279199 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12971419 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 8917741 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 26382279 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 24510496 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 20064185 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 20950940 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 17084249 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 17084249 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17084249 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17084249 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9280206 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21520588 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18623165 — Biomarker: CTLA4
Type: Predictive Biomarker (PRD)
Genes: CD152; CD; GSE; CTLA-4
Study 8157946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25106447 — Biomarker: DARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DARS1; DARS; PIG40
Study 11850090 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2660893 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 30676666 — Biomarker: HADHA mRNA
Type: Predictive Biomarker (PRD)
Genes: HADHA; HADH
Study 30676666 — Biomarker: QDPR mRNA
Type: Predictive Biomarker (PRD)
Genes: QDPR; DHPR; SDR33C1
Study 29911772 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 3096633 — Biomarker: EED mRNA
Type: Predictive Biomarker (PRD)
Genes: EED
Study 3096633 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 3096633 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3096633 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21919543 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19883295 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 19883295 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11734672 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 11734672 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11734672 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8060578 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8060578 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 2054714 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 24450390 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24450390 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21714897 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14992872 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 6148868 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30717815 — Biomarker: NR3C1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR3C1; GRL
Study 21505910 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11323536 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 7909525 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9442429 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 3339790 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26958799 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23110878 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 21612625 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 11741555 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7587599 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31013820 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 9443459 — Biomarker: CNTF mRNA
Type: Predictive Biomarker (PRD)
Genes: CNTF
Study 9443459 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17329276 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 17329276 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 17329276 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9893219 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27865949 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 27865949 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27865949 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 23594787 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27594122 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10434235 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7607582 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21545485 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9037324 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22569889 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20975026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12543884 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12543884 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12959304 — Biomarker: Hypoxanthine-guanine phosphoribosyltransferase
Type: Safety Biomarker (SAF)
Genes: HPRT1; HPRT
Study 19267711 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19267711 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21092030 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21092030 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 10472341 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 24935879 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 22548646 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 10353069 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10353069 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30520566 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 30520566 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23040570 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20020412 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15053242 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10561336 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31727687 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30725411 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 12622925 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21974699 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8346826 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 22330753 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15990003 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 29898788 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 27840257 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 23598957 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23598957 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20863432 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 20863432 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 20863432 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15883431 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9174874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22409295 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 24499010 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10583435 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 10583435 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 8904612 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1678925 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28395936 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 23748507 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 29849032 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20520293 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 16192477 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16192477 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 17595259 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study 17595259 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 17595259 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 14734000 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9810957 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 21651908 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 21651908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19288084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1881978 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 6578752 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 6578752 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30544716 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20660224 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 16132323 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16132323 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24382030 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24382030 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22039165 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19131212 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10609905 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 16182162 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7657740 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 31109313 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 28236981 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 23403268 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 23403268 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14510624 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9074702 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9074702 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 9074702 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 16482073 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 8426204 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 20026784 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 20026784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20026784 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12649629 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2427840 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25151098 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10385633 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8689882 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 8689882 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study 8689882 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 8689882 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8689882 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 30460483 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 2181565 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28418102 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 9744982 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26364276 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 24267039 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24267039 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24267039 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 17996819 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17996819 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 7657008 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 26401986 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 12215958 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 23290835 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11357021 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11357021 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29235659 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29235659 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25145693 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17092242 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 25173199 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20691689 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 20691689 — Biomarker: FGFR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR4; JTK2; TKF