AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 16477089 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10150534 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 23783643 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16928807 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9440663 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3263868 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27121901 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 25013367 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31138316 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27176631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8390511 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8390511 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3720365 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16917901 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11751712 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29960156 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 25640020 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 21199294 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10699324 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 23171880 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23171880 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 21607987 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19489765 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9525336 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 9525336 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28929400 — Biomarker: FADS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS1; FADSD5
Study 22958105 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 20670400 — Biomarker: HFE mRNA
Type: Predictive Biomarker (PRD)
Genes: HFE; HLAH
Study 11029348 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11029348 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 12374449 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 9931196 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 11113068 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 24447085 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 20134408 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20134408 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 18800994 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2291870 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28596452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11870117 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25369277 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21859489 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 8029191 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15321623 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8170529 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 23171639 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 10805207 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24769011 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24769011 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17106718 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15741989 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12067941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12067941 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12067941 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12067941 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2374566 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 361463 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28619061 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 28619061 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12472796 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8478661 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 26526702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22032285 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 17971716 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21596364 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21596364 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2505269 — Biomarker: TTPA mRNA
Type: Predictive Biomarker (PRD)
Genes: TTPA; TPP1
Study 20199786 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20199786 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11973215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25239479 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11773293 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27524498 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 15452182 — Biomarker: ZBTB7A mRNA
Type: Predictive Biomarker (PRD)
Genes: ZBTB7A; FBI1; LRF; ZBTB7; ZNF857A
Study 9098477 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 9098477 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 8082875 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 8082875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31023432 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9870472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21911723 — Biomarker: PLXNA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 17900778 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 24767603 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 20339354 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18823460 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7595953 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31625020 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 31625020 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27256706 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 11531952 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11531952 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12965981 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26903712 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 26903712 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25062420 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25062420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25062420 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17574819 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17574819 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25672274 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 17168431 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 8889855 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20236990 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 31843638 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29727043 — Biomarker: Serum asparaginase
Type: Surrogate Endpoint (SUR)
Study 24928586 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24928586 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7789631 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7789631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17470864 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17470864 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17470864 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23601264 — Biomarker: EMB mRNA
Type: Predictive Biomarker (PRD)
Genes: EMB
Study 3341391 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3341391 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 3341391 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 3341391 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31424957 — Biomarker: SOX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOX2
Study 26814847 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 23754758 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21472664 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21472664 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9080918 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30485450 — Biomarker: CEMIP mRNA
Type: Predictive Biomarker (PRD)
Genes: CEMIP; KIAA1199
Study 12912807 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 12912807 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24755206 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15353973 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15353973 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15353973 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9870830 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27940188 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 23818981 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 19436136 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 19436136 — Biomarker: GGCX mRNA
Type: Predictive Biomarker (PRD)
Genes: GGCX; GC
Study 12844212 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10993791 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8996468 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31034598 — Biomarker: CD248 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD248; CD164L1; TEM1
Study 23375525 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 23375525 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 23375525 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23375525 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23375525 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23375525 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23375525 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21410828 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9824345 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2532184 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 26297701 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 26297701 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 31260526 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 23810874 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23810874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28606620 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 25809853 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25809853 — Biomarker: Plasma sitosterol and campesterol
Type: Surrogate Endpoint (SUR)
Study 25809853 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 10631214 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16086559 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 7827843 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 26678630 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21550084 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21550084 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 6381166 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27081016 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12351377 — Biomarker: CEBPA mRNA
Type: Predictive Biomarker (PRD)
Genes: CEBPA; CEBP
Study 12351377 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 24089227 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8205303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31228031 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 10993032 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24709487 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24709487 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 12745799 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 8340983 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12556405 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 12556405 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 956557 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21647703 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21647703 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11140385 — Biomarker: HPGDS mRNA
Type: Predictive Biomarker (PRD)
Genes: HPGDS; GSTS; PGDS; PTGDS2
Study 7950179 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 28811158 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 21128879 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 21128879 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21128879 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16983056 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11044422 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29713889 — Biomarker: FGG mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGG; PRO2061
Study 10931808 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 10931808 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 31732851 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31732851 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21668768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14699021 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14699021 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19001202 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19001202 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 19001202 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19001202 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19001202 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19001202 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 2985395 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30207079 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26663540 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 25126867 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25126867 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18360659 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 16737046 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16737046 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 16737046 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 10688158 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 24119856 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 21917299 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 21917299 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21917299 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17157442 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7549418 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 31344386 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 27150460 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 27150460 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 21511526 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 15231010 — Biomarker: New morphometric vertebral fractures
Type: Surrogate Endpoint (SUR)
Study 31578273 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31578273 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 27027204 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 19952780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19069453 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 19069453 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 16809906 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 29369166 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 29369166 — Biomarker: CCL24 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL24; MPIF2; SCYA24
Study 29369166 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 29369166 — Biomarker: PCOLCE mRNA
Type: Predictive Biomarker (PRD)
Genes: PCOLCE; PCPE1
Study 28698390 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 21535040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16547619 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 16547619 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)