AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 20492655 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20492655 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19167588 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19167588 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15278749 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7863047 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25073921 — Biomarker: VGF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: VGF
Study 22442773 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 17511155 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15625210 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10357349 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10357349 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31762338 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25885095 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7562888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17175037 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 9287241 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 18728266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18728266 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 6435703 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 28386694 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27862178 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27862178 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 1430286 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 11036470 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20210615 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18329126 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 15949731 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19158197 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 9395005 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 8179173 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28959911 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 28959911 — Biomarker: FAU mRNA
Type: Predictive Biomarker (PRD)
Genes: FAU
Study 16532017 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study 10749297 — Biomarker: PTRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTRH1; C9orf115
Study 29490101 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 28628702 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30543598 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30543598 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16133961 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 11864514 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7805900 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 1952472 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1952472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1952472 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31770287 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 31770287 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 19847078 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 20107198 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18046669 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2208013 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21606537 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21606537 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19117121 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16076380 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 10072008 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23729801 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 19398651 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10088066 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15465986 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 11145479 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 11145479 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 7989902 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 17563401 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 17563401 — Biomarker: HMGCR mRNA
Type: Predictive Biomarker (PRD)
Genes: HMGCR
Study 16274919 — Biomarker: GLS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS2; GA
Study 7729640 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2188772 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2188772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6771173 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 6771173 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 30560679 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 16060911 — Biomarker: SSTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SSTR1
Study 16060911 — Biomarker: SSTR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SSTR2
Study 14607681 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 29166140 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29166140 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26494833 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24346757 — Biomarker: ELK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELK3; NET; SAP2
Study 20631210 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 18167173 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18167173 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18167173 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 18167173 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10982347 — Biomarker: EIF2AK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EIF2AK2; PKR; PRKR
Study 1462021 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1462021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28617537 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28617537 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22676856 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23649042 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18268858 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 11790928 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10216073 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10216073 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 8682055 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8682055 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8682055 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2184556 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31688650 — Biomarker: MMD mRNA
Type: Predictive Biomarker (PRD)
Genes: MMD; PAQR11
Study 29034644 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 22269963 — Biomarker: CEBPA mRNA
Type: Predictive Biomarker (PRD)
Genes: CEBPA; CEBP
Study 9422299 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30367991 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 30367991 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31929371 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 31929371 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31929371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18981464 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 17125606 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10589000 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 30964435 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 23994882 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23994882 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22314980 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14769678 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 14769678 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2953865 — Biomarker: C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: C9
Study 10165114 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27258294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24943285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22564271 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 20629812 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12020302 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9792383 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2541397 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 1958436 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 616212 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17803344 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17803344 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8959154 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 26644241 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 26644241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1952269 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18286351 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17132537 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14529881 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1532534 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1532534 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1532534 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3921597 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 30293878 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30390684 — Biomarker: CRHR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CRHR1; CRFR; CRFR1; CRHR
Study 30390684 — Biomarker: NR3C1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR3C1; GRL
Study 30390684 — Biomarker: FKBP5 mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: FKBP5; AIG6; FKBP51
Study 20932411 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 12386644 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7748969 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30033879 — Biomarker: MTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 17451796 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 7542473 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 30602032 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30602032 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26430694 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3132868 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3089490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29330911 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 26820653 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26820653 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26820653 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 25547247 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25547247 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22459636 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 17135854 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25453395 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25453395 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23218100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23218100 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23218100 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21949049 — Biomarker: PPARG mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARG; NR1C3
Study 21949049 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11704601 — Biomarker: Proliferation marker protein Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67
Study 21794899 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 9377855 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7794289 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20721516 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3140687 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 3140687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30999110 — Biomarker: Derived neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 30999110 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 30999110 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25432415 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 25432415 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17017486 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30353590 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 30353590 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 15937294 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15937294 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 7272161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30429050 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 26685691 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 31227278 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25710943 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25710943 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 25710943 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25710943 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25710943 — Biomarker: IL1B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL1F2; IL-1B; IL1-BETA
Study 16260422 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 9799029 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7900700 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 2793707 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 367713 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 29297443 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16483659 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 16304259 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10213219 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 26418025 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26007637 — Biomarker: KCNQ2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNQ2
Study 11684212 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7833220 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31815661 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 21631570 — Biomarker: Nicotinamide phosphoribosyltransferase
Type: Safety Biomarker (SAF)
Genes: NAMPT; PBEF; PBEF1
Study 21631570 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21631570 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12661619 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 21386830 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 21386830 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21386830 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19564877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17178091 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 11736720 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 27927936 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25548848 — Biomarker: CFL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CFL1; CFL
Study 23426761 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 21420111 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 9296641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9296641 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15262604 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9101427 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9101427 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 8468114 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29911495 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29911495 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 2523664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27315439 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 22051153 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 22051153 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 17230618 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15039245 — Biomarker: COMMD3 mRNA
Type: Predictive Biomarker (PRD)
Genes: COMMD3; BUP; C10orf8
Study 15039245 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11755834 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31042340 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28387927 — Biomarker: Plasma DNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28387927 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 14985690 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 9185038 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24893332 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18341596 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 8922653 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1352717 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF