AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 26621631 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26621631 — Biomarker: TLR2
Type: Predictive Biomarker (PRD)
Genes: TIL4; CD282
Study 22075942 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 12900342 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12900342 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 12900342 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 27633250 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21673083 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21673083 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16528977 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9432405 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1576046 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12771007 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 7287240 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26484902 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 22963378 — Biomarker: ID1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ID1; BHLHB24; ID
Study 15305311 — Biomarker: LARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LARS1; KIAA1352; LARS
Study 8062521 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29325660 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 22512264 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20810376 — Biomarker: COPE mRNA
Type: Predictive Biomarker (PRD)
Genes: COPE
Study 30125457 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21733177 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21733177 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21733177 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16704986 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 7555530 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7555530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2340615 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15058157 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 29866583 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20129356 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 18392690 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18392690 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31765604 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 19996335 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18446021 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12881451 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6398983 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30550982 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30550982 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30550982 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22261578 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7152443 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 15705733 — Biomarker: PPARGC1A mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1
Study 9854508 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 329291 — Biomarker: DMTN mRNA
Type: Predictive Biomarker (PRD)
Genes: DMTN; DMT; EPB49
Study 31472930 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23816493 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3666661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25515553 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25515553 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 22901969 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 7669483 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31862174 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7996800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24508036 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22730850 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11249891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25724847 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 10671676 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 10671676 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29726280 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27546373 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22689417 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11177300 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9076203 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9076203 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8360066 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24384495 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 30982983 — Biomarker: PIAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PIAS1; DDXBP1
Study 30982983 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 25281223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23812296 — Biomarker: LRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LRP1; A2MR; APR
Study 23812296 — Biomarker: Urokinase plasminogen activator surface receptor
Type: Monitoring Biomarker (MOI)
Genes: PLAUR; MO3; UPAR
Study 23812296 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1416164 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22212113 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 6779371 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20826553 — Biomarker: GNB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNB3
Study 8239101 — Biomarker: GSC mRNA
Type: Predictive Biomarker (PRD)
Genes: GSC
Study 18579283 — Biomarker: TPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH1; TPH; TPRH; TRPH
Study 12006956 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 7473451 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 7473451 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 7473451 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 1685182 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 6315329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1611649 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30561059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26582633 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26582633 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26582633 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9869598 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 9869598 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9869598 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9869598 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9869598 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 20298820 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 15764039 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 7805972 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23511556 — Biomarker: NCOA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NCOA3; AIB1; BHLHE42; RAC3; TRAM1
Study 23511556 — Biomarker: E2F1 mRNA
Type: Predictive Biomarker (PRD)
Genes: E2F1; RBBP3
Study 19081393 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8440931 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 3619219 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28350401 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9021437 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7940144 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31246714 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 16927920 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 12830439 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 14639559 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2442506 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28315068 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28315068 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 26508749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26508749 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14606508 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16820373 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16820373 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16820373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15585141 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24630293 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 15764959 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15764959 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29666071 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 8190534 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3296979 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3296979 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 20097461 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20097461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8701396 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 8701396 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 8701396 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 1521779 — Biomarker: Connecting peptide
Type: Safety Biomarker (SAF)
Genes: AHSG; FETUA; PRO2743
Study 1521779 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1521779 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 31964428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23040657 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22185726 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22185726 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 22185726 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24219814 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 20880093 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 18926162 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 14756461 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 31092019 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31092019 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23169362 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23169362 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16014845 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10193779 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 26109814 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 26109814 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26109814 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8021573 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2561594 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2561594 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16152600 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 8744166 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 31002147 — Biomarker: ADIPOQ mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 18538118 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10229733 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17571284 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 355958 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19458605 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16317423 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 16317423 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 16317423 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3302148 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27209269 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 25189358 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 15630733 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12021690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8547380 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 30989966 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 28419834 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26814106 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26814106 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23014927 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 16796836 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18192132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16169353 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 10229296 — Biomarker: PLK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLK2; SNK
Study 26681630 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21481265 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21975580 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 21975580 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 21975580 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 16019368 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 8027217 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 8027217 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 26473986 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26473986 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22211402 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 22211402 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 7670342 — Biomarker: MERTK mRNA
Type: Predictive Biomarker (PRD)
Genes: MERTK; MER
Study 25526906 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25526906 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23648344 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1551748 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31618127 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 24772445 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24772445 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20159245 — Biomarker: CAMP mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMP; CAP18; FALL39; HSD26
Study 20159245 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 20159245 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 20159245 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11821721 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31779925 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21130977 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17984166 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17984166 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7931739 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19470154 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 17894335 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 15041714 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 11585606 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 9823478 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 19897470 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19453396 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 27005463 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study 27005463 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 6128451 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22526529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1847023 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1847023 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 24572590 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 22525773 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22525773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15760426 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15760426 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12409657 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 26659706 — Biomarker: BOC mRNA
Type: Predictive Biomarker (PRD)
Genes: BOC; UNQ604/PRO1190
Study 10550566 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29469022 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 29469022 — Biomarker: GNB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNB3
Study 17492590 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 16198334 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12195347 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4