AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 16618363 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 24685604 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24685604 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11090788 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11090788 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20491360 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11835037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12523874 — Biomarker: NE
Type: Predictive Biomarker (PRD)
Study 29173603 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14555261 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31685212 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 31685212 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 31685212 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16195034 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12012138 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 7557813 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 2149728 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31445061 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17186282 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 24183981 — Biomarker: IVNS1ABP mRNA
Type: Predictive Biomarker (PRD)
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068
Study 12379622 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9579768 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9579768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7543956 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 28244612 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28244612 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28244612 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10202747 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 24218041 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24218041 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 24218041 — Biomarker: Angiopoietin-1
Type: Monitoring Biomarker (MOI)
Genes: ANGPT1; KIAA0003
Study 24218041 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17252567 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 23373541 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17302058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12765886 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 12765886 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12765886 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 8675231 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24975366 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 11208843 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 28272164 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19286582 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19286582 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10451042 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 8665993 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22215335 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22215335 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22215335 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 4091997 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30813546 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 19215336 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17270090 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17270090 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 14709952 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8112372 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26406397 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26406397 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 14654535 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 14654535 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 1589555 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 3896595 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26732017 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23460233 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 18403668 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 18403668 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18403668 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 17488461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17488461 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11897280 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31841026 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 26095142 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 24125150 — Biomarker: ARID3B mRNA
Type: Predictive Biomarker (PRD)
Genes: ARID3B; BDP; DRIL2
Study 1785707 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28422864 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 28422864 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 24797262 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22633079 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22633079 — Biomarker: TNFSF10 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF10; APO2L; TRAIL
Study 1567626 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 19948872 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8645892 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 8645892 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1698429 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 1698429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24331773 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 7871107 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23601333 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28758951 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26040352 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15482074 — Biomarker: POLE mRNA
Type: Predictive Biomarker (PRD)
Genes: POLE; POLE1
Study 21450115 — Biomarker: SELENOP mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENOP; SELP; SEPP1
Study 9773794 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22858814 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11987981 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2691131 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2691131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2691131 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 10916106 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20237063 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 18537187 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 18537187 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 18537187 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18537187 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15893176 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 15893176 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10971545 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 22889573 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20179126 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20179126 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31366053 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 31366053 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31366053 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31366053 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 31366053 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 31366053 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 26503312 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27699493 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 27699493 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27699493 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 25367150 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23543666 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 20023348 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 20023348 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 17264975 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14984920 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 11686810 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 29803341 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 29715303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8768849 — Biomarker: PZP mRNA
Type: Predictive Biomarker (PRD)
Genes: PZP; CPAMD6
Study 8768849 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6637785 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25922614 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 17538537 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 16842478 — Biomarker: NPL mRNA
Type: Predictive Biomarker (PRD)
Genes: NPL; C1orf13
Study 16842478 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29858911 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 29858911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18003811 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16575382 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17198647 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10910446 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10910446 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 4093974 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31433997 — Biomarker: ITFG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITFG1; LNKN-1; TIP; CDA08
Study 11126523 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18444145 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12704501 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27152849 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 17912164 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 12045167 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 10073079 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24095220 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17566313 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12911367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2887192 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 12686409 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12686409 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12686409 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12686409 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 11078264 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 25091714 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17984125 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17984125 — Biomarker: TMPRSS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMPRSS13; MSP; TMPRSS11
Study 27576846 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 27576846 — Biomarker: MDM2
Type: Predictive Biomarker (PRD)
Genes: HDM2; MGC5370
Study 27576846 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 27576846 — Biomarker: MDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM2
Study 20151996 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 20151996 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12855261 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 2289410 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2289410 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31152468 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24916951 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24370303 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 24370303 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2682474 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12543892 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8011251 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20843978 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10871576 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 23752057 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 6414387 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30975599 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28327526 — Biomarker: NAIP mRNA
Type: Predictive Biomarker (PRD)
Genes: NAIP; BIRC1
Study 9233719 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2828818 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28591764 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 14642682 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14642682 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 14642682 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8977984 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 6204148 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6204148 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 19809363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14706762 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9926278 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23115341 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26948962 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20073212 — Biomarker: GCA mRNA
Type: Predictive Biomarker (PRD)
Genes: GCA; GCL
Study 15259516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2591060 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 2591060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31833226 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 11777191 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 4149613 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21526412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16505284 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3095503 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23995299 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 22935338 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22935338 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22935338 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 16164158 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 9538650 — Biomarker: ATP7B mRNA
Type: Predictive Biomarker (PRD)
Genes: ATP7B; PWD; WC1; WND
Study 8251842 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29301785 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29301785 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24593225 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24593225 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21751770 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 27655440 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 11758232 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 11758232 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 24635880 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22076708 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 22076708 — Biomarker: DNA repair endonuclease XPF
Type: Predictive Biomarker (PRD)
Genes: ERCC4; ERCC11; XPF
Study 22076708 — Biomarker: ERCC5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC5; ERCM2; XPG; XPGC
Study 22076708 — Biomarker: DNA mismatch repair protein MSH2
Type: Predictive Biomarker (PRD)
Genes: MSH2
Study 22076708 — Biomarker: XPAC mRNA
Type: Predictive Biomarker (PRD)
Genes: XPA; XPAC
Study 22076708 — Biomarker: ERCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC2; XPD; XPDC
Study 22076708 — Biomarker: XRCC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: XRCC3
Study 22076708 — Biomarker: DNMT3B mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMT3B
Study 22076708 — Biomarker: CCND1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND1; BCL1; PRAD1
Study 22076708 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 22076708 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1