AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 15359398 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 9709393 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26448381 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 7589035 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7589035 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 6930207 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31044463 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 22696863 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17393018 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 17393018 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9624598 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 7519693 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7519693 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7519693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28163068 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 28163068 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 14627865 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19892055 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19892055 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30025522 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 22475864 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 20417423 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18600492 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 12022177 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 29536389 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 24952693 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 17483542 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16305585 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 9794714 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21792066 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21792066 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18728037 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 9164988 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 29429464 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 18536787 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18536787 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12647275 — Biomarker: RETN mRNA
Type: Predictive Biomarker (PRD)
Genes: RETN; FIZZ3; HXCP1; RSTN; UNQ407/PRO1199
Study 12647275 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28390970 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 24866478 — Biomarker: PTGDR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 16255987 — Biomarker: SOBP mRNA
Type: Predictive Biomarker (PRD)
Genes: SOBP; JXC1
Study 16255987 — Biomarker: PTN mRNA
Type: Predictive Biomarker (PRD)
Genes: PTN; HBNF1; NEGF1
Study 11851659 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 31558473 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 31558473 — Biomarker: HRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: HRAS; HRAS1
Study 31558473 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 31558473 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25972054 — Biomarker: DCC mRNA
Type: Predictive Biomarker (PRD)
Genes: DCC; IGDCC1
Study 21253725 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11468543 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11468543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9721802 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16421011 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16421011 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 16421011 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16421011 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 2865677 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 29747966 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3135392 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 19262230 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31253162 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25564570 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 21981453 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27569438 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 27569438 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 18520598 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 8690823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1686814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8579030 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 1673284 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31689835 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 25546368 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 23433435 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 18971537 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10946911 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 28133908 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 28133908 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28133908 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 24312277 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12686329 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 12686329 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7573993 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 28951368 — Biomarker: ILK mRNA
Type: Predictive Biomarker (PRD)
Genes: ILK; ILK1; ILK2
Study 19939650 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19939650 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19729323 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 19729323 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 9027670 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 8312583 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 25005327 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23252007 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12817109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21799772 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 19489942 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 19489942 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23828329 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23828329 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23828329 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11349008 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 9462194 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9462194 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23890405 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study 2037387 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 28489464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22013957 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 20215461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12430779 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12430779 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8814371 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 1330574 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29903826 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 26999985 — Biomarker: NFIC mRNA
Type: Predictive Biomarker (PRD)
Genes: NFIC; NFI
Study 20932069 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8398496 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29847509 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 29847509 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 29847509 — Biomarker: SLC6A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 29847509 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 29847509 — Biomarker: PGR mRNA
Type: Predictive Biomarker (PRD)
Genes: PGR; NR3C3
Study 29847509 — Biomarker: HTR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2A; HTR2
Study 29847509 — Biomarker: HTR2B mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2B
Study 29847509 — Biomarker: HTR2C mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2C; HTR1C
Study 27418968 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 27418968 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 24079062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16126801 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9367476 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 1315121 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28980293 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27632909 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27632909 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20533217 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20533217 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16414385 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8379600 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24895799 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22935955 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18664026 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 6356899 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28361739 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 26518479 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 7713201 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 3372274 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15339999 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 11228382 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 1092210 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 28463756 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 28463756 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 28463756 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 26109992 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26109992 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 26109992 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9252712 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8325946 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27085126 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 27085126 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 27085126 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 24839206 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 18359186 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 12084809 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28559399 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25222091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19543909 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 19543909 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24252311 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 17643277 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15863650 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 15863650 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9535147 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7702050 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 2719498 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2719498 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18717761 — Biomarker: AEN mRNA
Type: Predictive Biomarker (PRD)
Genes: AEN; ISG20L1; SBBI58
Study 16210020 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 7854531 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 23529173 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21817186 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9777834 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27590372 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 20646533 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 20646533 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16350715 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 10594411 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31182139 — Biomarker: APOL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOL1; APOL
Study 31182139 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23551127 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 11158406 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11158406 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 7519005 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25707380 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 18635724 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17065274 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 10752747 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10752747 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 29354928 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29354928 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 29354928 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 20625263 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9643277 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24290290 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27879654 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 27879654 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 10215657 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 22453774 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15801015 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29378708 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27310327 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 27310327 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 21715138 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 21715138 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 18495607 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15677599 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 11240980 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 1361746 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28475670 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 23396736 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 23396736 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 15754082 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22151932 — Biomarker: SMG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMG1; ATX; KIAA0421; LIP
Study 16720126 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28407271 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 15320990 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3878905 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 3878905 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3878905 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 12069111 — Biomarker: Mitochondrial frataxin
Type: Monitoring Biomarker (MOI)
Genes: FXN; FRDA; X25
Study 15794869 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 12872394 — Biomarker: IL16
Type: Safety Biomarker (SAF)
Genes: LCF; IL-16; prIL-16; HsT19289; FLJ42735; FLJ16806
Study 10697624 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 971343 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28533305 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28533305 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28533305 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28533305 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16365070 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 16365070 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 10827226 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 10827226 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 1608903 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3885701 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3885701 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 3885701 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 26568577 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24798768 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 8523872 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 28176175 — Biomarker: WT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WT1
Study 28176175 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28176175 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 7946939 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1454657 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22958175 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2