AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 2006235 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 6344611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25166750 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 19293312 — Biomarker: CYP1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1B1
Study 2913769 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2913769 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10763145 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 31166081 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 31166081 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 24279026 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 9080151 — Biomarker: High-frequency oscillations
Type: Pharmacodynamic Biomarker (PDY)
Study 9080151 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9080151 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 24646311 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 16549945 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 9185751 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 17888202 — Biomarker: GPX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPX1
Study 17888202 — Biomarker: GCLC mRNA
Type: Predictive Biomarker (PRD)
Genes: GCLC; GLCL; GLCLC
Study 17888202 — Biomarker: Nqo1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: NQO1; DIA4; NMOR1
Study 9497213 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 9497213 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 7961545 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31755939 — Biomarker: Vitamin K-dependent protein C
Type: Safety Biomarker (SAF)
Genes: PROC
Study 20642550 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 20642550 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 31804424 — Biomarker: NTS mRNA
Type: Predictive Biomarker (PRD)
Genes: NTS
Study 26501782 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26501782 — Biomarker: SLC38A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 9648992 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 2537340 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 14988614 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 28350929 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 15138958 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8301432 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2500040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16883311 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16883311 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 27979046 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26028058 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 20220206 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 10188752 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10188752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2531153 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24997614 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24997614 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24997614 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8450243 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24805282 — Biomarker: RRAD mRNA
Type: Predictive Biomarker (PRD)
Genes: RRAD; RAD
Study 17703218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12422064 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8952580 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30329163 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 11546945 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22348983 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 22348983 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10563706 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1677822 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30007039 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 30201456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26787231 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 22166897 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22166897 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15015149 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15015149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15015149 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9645977 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26597211 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22371887 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 17537289 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11897434 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31390002 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 16769988 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21258804 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16377919 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 28003041 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28003041 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28003041 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 18302501 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 2021128 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8200988 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18164013 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 18164013 — Biomarker: LIPC mRNA
Type: Predictive Biomarker (PRD)
Genes: LIPC; HTGL
Study 31748594 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21969011 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11529585 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21551462 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12674333 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 12674333 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7372036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7372036 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 24798710 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20921939 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20921939 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 16624688 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12515871 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10428524 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1692687 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29354990 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 23417203 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 31770012 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17328356 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 8138330 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27282133 — Biomarker: TRPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPA1; ANKTM1
Study 27282133 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24722774 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19083404 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10518002 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30450601 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30450601 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23032205 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 23032205 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 16114163 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7587740 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7587740 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 7587740 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 7587740 — Biomarker: CD58 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD58; LFA3
Study 7188827 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 7052000 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 25377907 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20101013 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7488278 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26298832 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 9493932 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 23835824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20675956 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17283863 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12805334 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 31246895 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29902305 — Biomarker: CPD mRNA
Type: Predictive Biomarker (PRD)
Genes: CPD
Study 17852084 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29947099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27362794 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 19965915 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18340009 — Biomarker: ACAT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAT2; ACTL
Study 18340009 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 18340009 — Biomarker: APOE mRNA
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 7826828 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20629478 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17132757 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 20027108 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 16148457 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 16148457 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31838028 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 18645345 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17135607 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10735695 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26271204 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 23241227 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 14630840 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24894416 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 24894416 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 24894416 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10881265 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 6376207 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6376207 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31444995 — Biomarker: TERT mRNA
Type: Predictive Biomarker (PRD)
Genes: TERT; EST2; TCS1; TRT
Study 31444995 — Biomarker: STN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STN1; OBFC1
Study 31444995 — Biomarker: RTEL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RTEL1; C20orf41; KIAA1088; NHL
Study 26443018 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 26443018 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10395628 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 6941657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25369827 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22901562 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22901562 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17675054 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11328262 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9877109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2916485 — Biomarker: RAPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPH1; ALS2CR18; ALS2CR9; KIAA1681; LPD; PREL2; RMO1
Study 9630829 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 27462118 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8635384 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 30652260 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 16988133 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 12802915 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 12802915 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 12802915 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 12802915 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 28537508 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28537508 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27179104 — Biomarker: CLEC9A mRNA
Type: Predictive Biomarker (PRD)
Genes: CLEC9A; UNQ9341/PRO34046
Study 18084691 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11140880 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 11140880 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 21508389 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 21508389 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 21508389 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 16669956 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 7960013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26741384 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21080967 — Biomarker: PAG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAG1; CBP; PAG
Study 18207167 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6308068 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6308068 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26558729 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19342396 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 15133294 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15133294 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 15133294 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15133294 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15133294 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 12575588 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9782544 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9782544 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23160920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10512904 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7860749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6161534 — Biomarker: NAPA mRNA
Type: Predictive Biomarker (PRD)
Genes: NAPA; SNAPA
Study 31825471 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 28169450 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27151378 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 9649911 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 16998290 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 8513038 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 30704429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26860800 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26860800 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26860800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17545356 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 6378439 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 6378439 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 6378439 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20458350 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1643937 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 27964837 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 25942458 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24991090 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 22029869 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 15449576 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15449576 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 15449576 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 24646362 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 24646362 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24646362 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17531569 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9930484 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 25885807 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 22637738 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22008920 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22008920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16468059 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 8299527 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30989422 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30989422 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26273134 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 26273134 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 12656549 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31145713 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29550566 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 27865358 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21951325 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)