AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 28813214 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 28813214 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16941701 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12953339 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12953339 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12953339 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12953339 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 1390591 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 2861223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29469944 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 22316799 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 30741797 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23653426 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 23653426 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 21854068 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21854068 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21854068 — Biomarker: REN mRNA
Type: Predictive Biomarker (PRD)
Genes: REN
Study 19955890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8331198 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3013265 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29254067 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 19670459 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15155118 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15155118 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11238232 — Biomarker: CTBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CTBS; CTB
Study 11238232 — Biomarker: CLSTN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLSTN1; CS1; KIAA0911
Study 11238232 — Biomarker: CLSTN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLSTN2; CS2
Study 2543304 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 2543304 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 21557836 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study 29720378 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 29720378 — Biomarker: PCSK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK5; PC5; PC6
Study 27455316 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25424425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17587713 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15756035 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 7640431 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 7640431 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 7640431 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7640431 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31054159 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31054159 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25948166 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23541971 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20519697 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20519697 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11590500 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11590500 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8147960 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30883331 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 26707134 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29962254 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 29962254 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23518604 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3139285 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 3139285 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 3139285 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 26910333 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 26910333 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 16611715 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14606990 — Biomarker: TSTD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSTD1; KAT
Study 27447428 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 20561625 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30092952 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26896263 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 18618943 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31817080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27448761 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27448761 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 9848512 — Biomarker: Proliferation marker protein Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67
Study 31056306 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 31056306 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 21316752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17557211 — Biomarker: SRM mRNA
Type: Predictive Biomarker (PRD)
Genes: SRM; SPS1; SRML1
Study 26460661 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20130401 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 9749162 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2459514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12392830 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18586578 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19436039 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 12848875 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12848875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22180633 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 31369706 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 31369706 — Biomarker: A2M mRNA
Type: Predictive Biomarker (PRD)
Genes: A2M; CPAMD5; FWP007
Study 31369706 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 28066708 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 24423149 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 24423149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10098460 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 11812697 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 31017569 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19516185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9724682 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25035126 — Biomarker: SP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP2; KIAA0048
Study 15045502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29373148 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 29305130 — Biomarker: OGG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OGG1; MMH; MUTM; OGH1
Study 26599222 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 26599222 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20410835 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29685792 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29685792 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 17685675 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20537177 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 18566295 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27227933 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24703574 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10490792 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26094050 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 2108196 — Biomarker: HCG22 mRNA
Type: Predictive Biomarker (PRD)
Genes: HCG22; G2; PBMUCL2
Study 26519114 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26519114 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30556913 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 21292898 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 9296473 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21122057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11012557 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11012557 — Biomarker: DDR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 11012557 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 11012557 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31645472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28193176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22395672 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19775480 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 17213294 — Biomarker: UBXN11 mRNA
Type: Predictive Biomarker (PRD)
Genes: UBXN11; SOC; UBXD5; PP2243
Study 31729520 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19815243 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19815243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9917435 — Biomarker: ZMYM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZMYM2; FIM; RAMP; ZNF198
Study 31095461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26051163 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 11887037 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9170575 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9170575 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 21194608 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23622850 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 16671428 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27267710 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22678090 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12107216 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31768803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31768803 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31768803 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 2860990 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21178182 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 17705242 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 31764984 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31764984 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19533481 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 8294084 — Biomarker: Protein AMBP
Type: Safety Biomarker (SAF)
Genes: AMBP; HCP; ITIL
Study 8294084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31732448 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 28974102 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28028373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12190100 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11012554 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25933490 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25933490 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 371034 — Biomarker: OPN1SW mRNA
Type: Predictive Biomarker (PRD)
Genes: OPN1SW; BCP
Study 29576595 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 29576595 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 10890777 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 1835398 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 6119766 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 30261783 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30261783 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28973362 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 28973362 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21571547 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 18844760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 13680163 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6419958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21266513 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29304325 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 28070894 — Biomarker: TPI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPI1; TPI
Study 20981000 — Biomarker: HRH3 mRNA
Type: Predictive Biomarker (PRD)
Genes: HRH3; GPCR97
Study 15845499 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 11918735 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18552684 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12499279 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 12499279 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 7723402 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24165269 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24165269 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21897113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21897113 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20713790 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16001108 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 10614677 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19906103 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17293063 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17293063 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 17293063 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 17293063 — Biomarker: SOD2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SOD2
Study 17293063 — Biomarker: CXCL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL2; GRO2; GROB; MIP2A; SCYB2
Study 10023308 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 12719279 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8994512 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 8994512 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8994512 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8994512 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 8994512 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17408407 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 16061711 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 12429323 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 22610590 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 9250102 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 9250102 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8282290 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29982690 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 11414776 — Biomarker: PAG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAG1; CBP; PAG
Study 29805306 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29805306 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29805306 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27619215 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20484472 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 16648513 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 16648513 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 12970132 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 11191541 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9170041 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 1331788 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31582283 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 31582283 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26908041 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26908041 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17644545 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17644545 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1628722 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 14705236 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7665805 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 25740537 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 8273616 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28090203 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 18086800 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29793857 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 29793857 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 9695717 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3