AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23440253 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19524329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8546911 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 8546911 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 1884746 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31525174 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29370756 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 22045039 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 29190605 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 17473001 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 17473001 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7993161 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25434574 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25434574 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25434574 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14743580 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1349492 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1349492 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25135729 — Biomarker: PCSK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK5; PC5; PC6
Study 17912637 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17912637 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 2597598 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29805491 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 29805491 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12040355 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10069278 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30719237 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 25496958 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 20853602 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15338100 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 27662551 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 8757561 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8757561 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 1550481 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1550481 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16765589 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 1958387 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26258860 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 26258860 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11588120 — Biomarker: EDNRA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDNRA; ETA; ETRA
Study 11588120 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 31453902 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 31504139 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31504139 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 26409117 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 19173846 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29455305 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 27578220 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 23939415 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18257143 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8864317 — Biomarker: ASPRV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASPRV1; SASP
Study 8864317 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15653291 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 30106636 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30106636 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 27401244 — Biomarker: NRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRP1; NRP; VEGF165R
Study 31489650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28723843 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 25355640 — Biomarker: XRCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: XRCC2
Study 11291296 — Biomarker: ABCC6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC6; ARA; MRP6
Study 23782622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21346095 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 18501066 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18501066 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 18501066 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 17575805 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10894877 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 30077574 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11788642 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6785790 — Biomarker: CPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPZ
Study 21894690 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8393637 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 26901242 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26901242 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26901242 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12225549 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9857278 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 7883833 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 21609212 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 30191781 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 28225313 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 28225313 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 19114909 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10483132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2193640 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25919061 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 27187451 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27187451 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20184572 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 31427862 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31427862 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24526141 — Biomarker: STAR mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAR; STARD1
Study 23964444 — Biomarker: Interleukin 1 alpha
Type: Safety Biomarker (SAF)
Genes: IL1A; IL1F1
Study 23964444 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 23964444 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 20185666 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 17657838 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 15662503 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 11792748 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 22950641 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22950641 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22950641 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 22950641 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17517832 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11481357 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11481357 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28446376 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 26042933 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15617458 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11320384 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19586971 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9800180 — Biomarker: Hydroxyphenylpyruvate dioxygenase
Type: Safety Biomarker (SAF)
Genes: HPD; PPD
Study 24239156 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 3089491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11109313 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9195357 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30269900 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27327024 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 27327024 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 27327024 — Biomarker: PDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PDK4; PDHK4
Study 27327024 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 24293578 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24293578 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 24293578 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12822009 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 7867183 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 25828994 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23713032 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16733237 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16733237 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16733237 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25678098 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21921249 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 16978997 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16978997 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16978997 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 6859790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15893293 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 28915981 — Biomarker: SP8 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP8
Study 28915981 — Biomarker: CA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA1
Study 28915981 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 22836615 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 14648009 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31108918 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16447105 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1738926 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25060541 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16416642 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 10530413 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 31444180 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 1331443 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1331443 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18664303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12118026 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 12118026 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 8710065 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30277850 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11907491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1915205 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28490565 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 26062822 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study 19770395 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9566654 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 25955225 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 25955225 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25955225 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 19402938 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19402938 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19402938 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19402938 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9683400 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2974769 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 2974769 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28012242 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 16571285 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 9175690 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9175690 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 20347369 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9373766 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3894279 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15373933 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 21224289 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 16036075 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8738691 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 1540597 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20374034 — Biomarker: SOBP mRNA
Type: Predictive Biomarker (PRD)
Genes: SOBP; JXC1
Study 20374034 — Biomarker: RAB4A mRNA
Type: Predictive Biomarker (PRD)
Genes: RAB4A; RAB4
Study 20374034 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 16062074 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 11863244 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21977965 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 14638387 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 10883875 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 25038148 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12392343 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7503851 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30599109 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29030584 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 14686964 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 14686964 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7818958 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15812253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8576810 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 999987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30531488 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28419206 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31519167 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19464413 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31900758 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28615356 — Biomarker: Nuclear factor erythroid 2-related factor 2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: NFE2L2; NRF2
Study 26179616 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10770346 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28785986 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 26112745 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19273782 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28945992 — Biomarker: miR-192
Type: Safety Biomarker (SAF)
Genes: MIR192
Study 25759545 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 19127598 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 19127598 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 19127598 — Biomarker: Cyclin-dependent kinase inhibitor 1
Type: Safety Biomarker (SAF)
Genes: CDKN1A
Study 17455121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10220834 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 28425312 — Biomarker: SLC12A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC12A5; KCC2; KIAA1176
Study 28425312 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 28425312 — Biomarker: Tropomyosin-related kinase A
Type: Pharmacodynamic Biomarker (PDY)
Genes: NTRK1; MTC; TRK; TRKA
Study 25824475 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25824475 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 25824475 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25824475 — Biomarker: MMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP2; CLG4A
Study 25824475 — Biomarker: TIMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TIMP2
Study 25824475 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 24233255 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22660441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11401117 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 11401117 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 31654782 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 28372680 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 26148612 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8124838 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8124838 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26727743 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 25660340 — Biomarker: NES mRNA
Type: Predictive Biomarker (PRD)
Genes: NES; Nbla00170