AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 28012280 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 28012280 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28012280 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 20337221 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 20337221 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20337221 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10672977 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28090594 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28090594 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21741230 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 1357451 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 30348142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21993491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20178625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29947322 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 24664108 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 18803940 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2624617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2624617 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 11873073 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31076365 — Biomarker: Angiopoietin-1
Type: Monitoring Biomarker (MOI)
Genes: ANGPT1; KIAA0003
Study 19359148 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2670220 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28719834 — Biomarker: GHR mRNA
Type: Predictive Biomarker (PRD)
Genes: GHR
Study 24835417 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 19892540 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15976380 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 11350261 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 11350261 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 11350261 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 20473734 — Biomarker: Osteopontin
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SPP1; BNSP; OPN; PSEC0156
Study 6321195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29458237 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25005652 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 31382986 — Biomarker: SH2D1A mRNA
Type: Predictive Biomarker (PRD)
Genes: SH2D1A; DSHP; SAP
Study 21875209 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16455437 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12958610 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12958610 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9177404 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26387144 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 11737121 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11737121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8249784 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 24576196 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8141183 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8128938 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 17374708 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17374708 — Biomarker: RETN mRNA
Type: Predictive Biomarker (PRD)
Genes: RETN; FIZZ3; HXCP1; RSTN; UNQ407/PRO1199
Study 30280751 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27120177 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 27120177 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 27120177 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 27120177 — Biomarker: POR mRNA
Type: Predictive Biomarker (PRD)
Genes: POR; CYPOR
Study 7702024 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 7702024 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2503294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21342490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19724276 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19724276 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 226565 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19296248 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17768771 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 3631465 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11174292 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 9433426 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9433426 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8948741 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 795443 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9710300 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30578392 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 30578392 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22381428 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15356670 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11368462 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24535937 — Biomarker: DNMT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMT1; AIM; CXXC9; DNMT
Study 10841179 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 2873601 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24525155 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8282635 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 8282635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9049974 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 23530755 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21498906 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16325470 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16325470 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16325470 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12603413 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 29439650 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 25227833 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 25227833 — Biomarker: Ribonucleoside-diphosphate reductase large subunit
Type: Predictive Biomarker (PRD)
Genes: RRM1; RR1
Study 25227833 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 17852629 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 8907133 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 1696310 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 1696310 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 1696310 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study 1696310 — Biomarker: CD9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD9; MIC3; TSPAN29; GIG2
Study 1696310 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 1696310 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 17667021 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15565575 — Biomarker: DCC mRNA
Type: Predictive Biomarker (PRD)
Genes: DCC; IGDCC1
Study 15565575 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 7040493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11847411 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29490509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25575640 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18352997 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 9452847 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22752659 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21555294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11066029 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9337828 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 24014214 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 12865477 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12865477 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12865477 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31868694 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 23846354 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 23846354 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23846354 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 10831163 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30367238 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9602197 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2738909 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 28410886 — Biomarker: TDO2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TDO2; TDO
Study 26278649 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 26278649 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 23642944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21565322 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21565322 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9263186 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31539371 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27931053 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27931053 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 27931053 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19399262 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19399262 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17708625 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16787193 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 22692106 — Biomarker: MAX mRNA
Type: Predictive Biomarker (PRD)
Genes: MAX; BHLHD4
Study 18071079 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11099367 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 6086772 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 20811292 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study 20811292 — Biomarker: AGTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study 3280128 — Biomarker: OMD mRNA
Type: Predictive Biomarker (PRD)
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 30585267 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 30585267 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 30585267 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 28533148 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 16847290 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12704354 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 7249899 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 22914255 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22914255 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22914255 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3613407 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26189608 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 22918663 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18474764 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18474764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8617086 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 18981007 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 10482985 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 8144848 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 19167589 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19167589 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19167589 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15320851 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8029088 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 30629160 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29066163 — Biomarker: Anti-acetylcholine receptor antibody
Type: Predictive Biomarker (PRD)
Study 21520154 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 12764406 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23510450 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 20883866 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 18602599 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 18602599 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 18602599 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21723359 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 21723359 — Biomarker: SHMT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SHMT1
Study 21723359 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 17173248 — Biomarker: CCN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 17173248 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 12717205 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12717205 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27588932 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26061985 — Biomarker: PLXNB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLXNB1; KIAA0407; PLXN5; SEP
Study 23117015 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16426270 — Biomarker: NOTCH3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOTCH3
Study 15451899 — Biomarker: GAD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD2; GAD65
Study 12615747 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10850829 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24955739 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 15914346 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 27358159 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 22570370 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12487226 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 12487226 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 30825563 — Biomarker: c-Jun N-terminal kinase
Type: Safety Biomarker (SAF)
Study 30825563 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30825563 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 23572225 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 17904297 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 17904297 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 7851269 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 18511605 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2888302 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18196610 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 31340493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31340493 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 27725911 — Biomarker: NDP mRNA
Type: Predictive Biomarker (PRD)
Genes: NDP; EVR2
Study 3828955 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27510539 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 18752143 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 1347757 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1347757 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1347757 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2863220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8227863 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28148501 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 15531696 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9757152 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 3042356 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28173897 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 16930215 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 10894865 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 1589588 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 6747142 — Biomarker: KCNN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNN1; SK
Study 6747142 — Biomarker: RANGAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RANGAP1; KIAA1835; SD
Study 27856202 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25264877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19874572 — Biomarker: HFE mRNA
Type: Predictive Biomarker (PRD)
Genes: HFE; HLAH
Study 16386539 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16386539 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22941691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1836100 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31045798 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31045798 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31045798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26919177 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16392300 — Biomarker: CGN mRNA
Type: Predictive Biomarker (PRD)
Genes: CGN; KIAA1319
Study 16392300 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16392300 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 140029 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28595744 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 19112166 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19112166 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19112166 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19112166 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1