AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 28940709 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 26037798 — Biomarker: Derived neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 26037798 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 26037798 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23569146 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 21320331 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19165639 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7965266 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29082595 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27207917 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 15655130 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15655130 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12805489 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 8606643 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 28145073 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 2040035 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31069575 — Biomarker: MMRN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 26739742 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20179234 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 10199760 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23787155 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23787155 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14743544 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10877738 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15531675 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 31335733 — Biomarker: CCN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 25845224 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20718625 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 10563709 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18713921 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8117635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20448066 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 23901669 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17565326 — Biomarker: CD52 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD52; CDW52; HE5
Study 21348539 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 18509176 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18050628 — Biomarker: LSR mRNA
Type: Predictive Biomarker (PRD)
Genes: LSR; ILDR3; LISCH
Study 6834370 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31338545 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30428891 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 364615 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29654563 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 17040215 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 15124980 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 21655762 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21655762 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17276952 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3298752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3298752 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29807307 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 7848789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22968256 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22968256 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 21337878 — Biomarker: Tumor-infiltrating lymphocyte
Type: Predictive Biomarker (PRD)
Study 17032661 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28921935 — Biomarker: ADH1B mRNA
Type: Predictive Biomarker (PRD)
Genes: ADH1B; ADH2
Study 28921935 — Biomarker: CHRNA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA5; NACHRA5
Study 24841974 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24841974 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 19004511 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14514407 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 14514407 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 26511996 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20519376 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 20519376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1688495 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1688495 — Biomarker: CD7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD7
Study 1688495 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 1688495 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31063156 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23510984 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 16750696 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14508203 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10913471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10913471 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26392095 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21816786 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21816786 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 17023230 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24137215 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 16820589 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 16820589 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12759324 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25012288 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 16200817 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 16200817 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 484501 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19043151 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 31594719 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 31594719 — Biomarker: ABCG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 31594719 — Biomarker: ABCG2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 25583256 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17546381 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7995010 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26682747 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 21575292 — Biomarker: EMB mRNA
Type: Predictive Biomarker (PRD)
Genes: EMB
Study 22571902 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25114907 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 15249317 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9723435 — Biomarker: TRERF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRERF1; BCAR2; RAPA; TREP132
Study 23521115 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 10623692 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 18487480 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14768777 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10697397 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 10697397 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 21742514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21742514 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10404421 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29870591 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 29870591 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 21194357 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15727187 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29427024 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 29427024 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29427024 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25042737 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 16332235 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 12149667 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12149667 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11334905 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 22855038 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12463311 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 12463311 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10514159 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19095403 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16990966 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20124509 — Biomarker: CCND1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND1; BCL1; PRAD1
Study 20124509 — Biomarker: MAF mRNA
Type: Predictive Biomarker (PRD)
Genes: MAF
Study 20124509 — Biomarker: MAFB mRNA
Type: Predictive Biomarker (PRD)
Genes: MAFB; KRML
Study 11737044 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11737044 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 8292465 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22048714 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9293972 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8297841 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31997543 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 20626444 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15307543 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 10903236 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 10903236 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10903236 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 8110072 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 31023258 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 16825088 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16825088 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 30439793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27924398 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 21273893 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21273893 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21273893 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15257845 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9504568 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 26569545 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15747253 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24610312 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 22460142 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22460142 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 12420344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27852303 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27852303 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 27852303 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27852303 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 8251721 — Biomarker: NXN mRNA
Type: Predictive Biomarker (PRD)
Genes: NXN; NRX
Study 17697209 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 16123474 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16123474 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11852667 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10431553 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 30760581 — Biomarker: APC
Type: Safety Biomarker (SAF)
Genes: DP2; DP3; DP2.5; PPP1R46
Study 28381796 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 20718814 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20718814 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20718814 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17701048 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15970291 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15970291 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15970291 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28634822 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26445565 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15745291 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 3307390 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29150328 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 16034044 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16034044 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 16034044 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16034044 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16034044 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 16034044 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 10065905 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 24037998 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 22359979 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23380000 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 21725513 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 21725513 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 15025747 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 15025747 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 12423708 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24188161 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24188161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30277569 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 20399327 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9695714 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 9695714 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 30408155 — Biomarker: IGFBP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP2; BP2; IBP2
Study 30408155 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 30408155 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 25238251 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19641984 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17134892 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 20704642 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 20704642 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 15490268 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15490268 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28272402 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17057135 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 28043438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25904747 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 25904747 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25904747 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18825772 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10984077 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31620931 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30032191 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30032191 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27084589 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 14604567 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30368495 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 30368495 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 26857107 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22596166 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22596166 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22596166 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 22596166 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22596166 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 20634720 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20634720 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30909863 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22749917 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)