AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 26805435 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 7641409 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 7641409 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 21235821 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 15900307 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15900307 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 15900307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12802453 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9796889 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9796889 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 27965180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23477506 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 23477506 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21566054 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8989173 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 3318461 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 29540324 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 29540324 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 27042193 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 27042193 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 11095657 — Biomarker: Complement factor D
Type: Safety Biomarker (SAF)
Genes: CFD; DF; PFD
Study 11095657 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 9123711 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29921153 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27095306 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 8703646 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26403745 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26403745 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26403745 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7942668 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 22187388 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 22187388 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22187388 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 17805230 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17805230 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 2951823 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26227186 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24079283 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24079283 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29926514 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9651905 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29501590 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 29501590 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 29501590 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 26799247 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26799247 — Biomarker: Urokinase plasminogen activator surface receptor
Type: Monitoring Biomarker (MOI)
Genes: PLAUR; MO3; UPAR
Study 16002030 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25851383 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25851383 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 25851383 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 25851383 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20413454 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20413454 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18716761 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 18716761 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 10219066 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7484276 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 7484276 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2298863 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2298863 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27077673 — Biomarker: BOC mRNA
Type: Predictive Biomarker (PRD)
Genes: BOC; UNQ604/PRO1190
Study 27077673 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 27077673 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 22909899 — Biomarker: GAPDH mRNA
Type: Predictive Biomarker (PRD)
Genes: GAPDH; GAPD; CDABP0047; OK/SW-cl.12
Study 18076252 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11854873 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10400005 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16570894 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 16570894 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9510449 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29136336 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 29136336 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 29136336 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 29136336 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 29136336 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 29136336 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 29136336 — Biomarker: HTR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2A; HTR2
Study 29136336 — Biomarker: HTR2C mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2C; HTR1C
Study 24062546 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 24062546 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 15860348 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 15860348 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 15860348 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 12412210 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8810809 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 29192535 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 9495396 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9495396 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2463406 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 322547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24126948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11926625 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 19369318 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15522252 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 9314625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17505923 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30520976 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30520976 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30520976 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30520976 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28177745 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 31655801 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21870106 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 21870106 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 21870106 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 21870106 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 2694203 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 11129359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31476159 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22389080 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22389080 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 22389080 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 12453549 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11289568 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 10803803 — Biomarker: L-acetylcarnitine
Type: Safety Biomarker (SAF)
Study 29801061 — Biomarker: MC1R mRNA
Type: Predictive Biomarker (PRD)
Genes: MC1R; MSHR
Study 27590876 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27590876 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 10841227 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10367620 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2029011 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 28965435 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24260764 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21288804 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 9005368 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3893704 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24924991 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9551029 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22788525 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 9917047 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 9917047 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 9917047 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 20332352 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 7502281 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 2310576 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7002568 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30477816 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26087958 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26087958 — Biomarker: AIP mRNA
Type: Predictive Biomarker (PRD)
Genes: AIP; XAP2
Study 26087958 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26087958 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26087958 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16682725 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 31382028 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28808808 — Biomarker: CARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARS1; CARS
Study 23438101 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23438101 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23438101 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17060116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27555197 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25001159 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 22585883 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7598089 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27323792 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25085017 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22079554 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 22079554 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22079554 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21171669 — Biomarker: SLC38A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 17924869 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25470694 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 22130391 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 7988310 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22795519 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21275162 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15745936 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15745936 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15745936 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9163067 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 9163067 — Biomarker: PLG mRNA
Type: Predictive Biomarker (PRD)
Genes: PLG
Study 9163067 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 21806767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11545288 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 8558934 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 1921252 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1921252 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28137295 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 25567051 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2739575 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 2739575 — Biomarker: TEF mRNA
Type: Predictive Biomarker (PRD)
Genes: TEF; KIAA1655
Study 25922426 — Biomarker: MT2A mRNA
Type: Predictive Biomarker (PRD)
Genes: MT2A; CES1; MT2
Study 21382896 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 18027383 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 3758142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31756281 — Biomarker: CSF1R mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF1R; FMS
Study 31756281 — Biomarker: AWAT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AWAT2; DC4; DGAT2L4; MFAT; WS
Study 24732241 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24732241 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30730000 — Biomarker: GSC mRNA
Type: Predictive Biomarker (PRD)
Genes: GSC
Study 17925866 — Biomarker: CPE mRNA
Type: Predictive Biomarker (PRD)
Genes: CPE
Study 28159819 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23574713 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 18222275 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 30700328 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 9175044 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9175044 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29193677 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10323511 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 6344035 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6344035 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30160789 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 25112087 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19657398 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9869229 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 31337697 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25381051 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 21676221 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7990904 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27067259 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 20668047 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29092882 — Biomarker: EED mRNA
Type: Predictive Biomarker (PRD)
Genes: EED
Study 17483155 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 23612197 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18850765 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 25230559 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23773316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19394598 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 9437192 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 25348157 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20033055 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 20033055 — Biomarker: KLRC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRC1; NKG2A
Study 20033055 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 20033055 — Biomarker: KLRD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRD1; CD94
Study 20033055 — Biomarker: KLRC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRC2; NKG2C
Study 6702864 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6702864 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27863065 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20395941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19018919 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3292598 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18385499 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29951742 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 12072673 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11792284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17014560 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31058534 — Biomarker: NBPF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NBPF1; KIAA1693
Study 31058534 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 31058534 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 24316514 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 10634196 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7081040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20421333 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 18775846 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR