AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 27545119 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 21569380 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 21569380 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21569380 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 21569380 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 17974096 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14507293 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29138200 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16845626 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16845626 — Biomarker: Interleukin 7 receptor alpha
Type: Pharmacodynamic Biomarker (PDY)
Genes: IL7R
Study 1872925 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18373843 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 18373843 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9091027 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23842110 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23842110 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23842110 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9412256 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 8241226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25981560 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 9366100 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 9366100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9366100 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15476910 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8498314 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26559015 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 16126716 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21926097 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 7866603 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7866603 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31381364 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26129900 — Biomarker: SP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP4
Study 12975660 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 11079643 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8947886 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 650879 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 650879 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30649918 — Biomarker: TSTD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSTD1; KAT
Study 23558806 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 23558806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19944358 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14970962 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 10023644 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 10023644 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10023644 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10023644 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30973207 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26508675 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26508675 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 19383582 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17223540 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 29888582 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 27993811 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 18328842 — Biomarker: TPI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPI1; TPI
Study 17009230 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6376484 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27121115 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24520782 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 16398599 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 12087922 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10617243 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10617243 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8538903 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8538903 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31899122 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 27179796 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17146370 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12164804 — Biomarker: PHEX mRNA
Type: Predictive Biomarker (PRD)
Genes: PHEX; PEX
Study 31549356 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29341404 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 24915612 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9706062 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 30294974 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 18378859 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10877010 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 8193735 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8193735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15717211 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12760988 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3404814 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 21949643 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12111127 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 26517283 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 26517283 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 25288176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28479852 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 28479852 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 1729935 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29278428 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 26991619 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9681726 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9681726 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 2572699 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 23057058 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 8115195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 793706 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 793706 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28923573 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28923573 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 28923573 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 21784378 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21784378 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15487693 — Biomarker: Major prion protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRNP; ALTPRP; PRIP; PRP
Study 10024902 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10024902 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8002124 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30498758 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 16046716 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 16046716 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24362488 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20197194 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11857045 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 7564082 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 22091554 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 19284108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2879733 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28335697 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28335697 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27339453 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16276166 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16276166 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 16276166 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 23131078 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10622346 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 29890569 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22682022 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15894592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30633202 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18554182 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10617008 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 19017751 — Biomarker: ENPP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ENPP1; M6S1; NPPS; PC1; PDNP1
Study 11266197 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11266197 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 11266197 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7987882 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2547465 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26496720 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 23680766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11028740 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16464637 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 16464637 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 14500473 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 10710869 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8992904 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30530284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19840063 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 19840063 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15361517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6141317 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22864525 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 6848299 — Biomarker: DCT mRNA
Type: Predictive Biomarker (PRD)
Genes: DCT; TYRP2
Study 27649854 — Biomarker: miR-30c
Type: Safety Biomarker (SAF)
Study 27649854 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 23161305 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18780501 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 19859781 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19859781 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19859781 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 12414852 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 8961992 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1742507 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 31931762 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19757215 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8822535 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 1532613 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22960288 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 20456282 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17265078 — Biomarker: SLC6A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A1; GABATR; GABT1; GAT1
Study 24267043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24267043 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22384541 — Biomarker: ACTA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACTA1; ACTA
Study 11403751 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26968165 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28362562 — Biomarker: KIT
Type: Predictive Biomarker (PRD)
Genes: CD117; SCFR; C-Kit
Study 28362562 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 16736432 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 16736432 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 16736432 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10082852 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 10082852 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 10082852 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 23019939 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7005474 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27885763 — Biomarker: ACAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAT1; ACAT; MAT
Study 21437363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18035430 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 30597578 — Biomarker: PER2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PER2; KIAA0347
Study 30597578 — Biomarker: POMC mRNA
Type: Predictive Biomarker (PRD)
Genes: POMC
Study 27079717 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 22990330 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 16967682 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 3057674 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24354929 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24354929 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24354929 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22733462 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22733462 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 26062916 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 23588439 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20378504 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 20378504 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 17037284 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17037284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7575771 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7870911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24474396 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28077588 — Biomarker: SLA mRNA
Type: Predictive Biomarker (PRD)
Genes: SLA; SLAP; SLAP1
Study 24241092 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24241092 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19846849 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19846849 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17584910 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 9580247 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 9580247 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 9580247 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20530505 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 16608040 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16608040 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30452713 — Biomarker: RNASE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RNASE2; EDN; RNS2
Study 26868849 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 26868849 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 15836710 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10480285 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 8728306 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24463448 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 17646219 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15142875 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 11161543 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 27919627 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23475636 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16476851 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 15379272 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 8992351 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31978565 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24998617 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24998617 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 24998617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23163616 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 23163616 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 11390253 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 27393499 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27393499 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2