AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 30632413 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 6835735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18670735 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2883908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25388906 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 9458147 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 24799686 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19902046 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 16909188 — Biomarker: EMP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EMP1; B4B; TMP
Study 15072506 — Biomarker: Alpha-glutathione S-transferase
Type: Safety Biomarker (SAF)
Study 15072506 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23744513 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30699039 — Biomarker: LARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LARS1; KIAA1352; LARS
Study 2826066 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28629344 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23647406 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 16776894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12830438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1588829 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27061991 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12449158 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 21400790 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 25778445 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25778445 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 31015098 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 22313171 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22313171 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10480508 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30957443 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26003804 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 23172931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19366957 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 19366957 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8102918 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 25519029 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25519029 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 20025554 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15946554 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10388978 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11803613 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 7870633 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2846455 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12450711 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 2285584 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 31884320 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 10566550 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 6185788 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28107276 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 28107276 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26253567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18051724 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18051724 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 18051724 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16052334 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 11985388 — Biomarker: CACNA1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CACNA1A; CACH4; CACN3; CACNL1A4
Study 8545141 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 1901528 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19403719 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 15459610 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 10363944 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 26156073 — Biomarker: TSC2
Type: Predictive Biomarker (PRD)
Genes: tuberin; LAM; PPP1R160
Study 24447434 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 24447434 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 24447434 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 10211629 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 14680725 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17361522 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11712434 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 8805994 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19115636 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 11369627 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12881348 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27009515 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18534276 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18534276 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 18534276 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12459658 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 23285026 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 11807777 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 11807777 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 30043934 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 19819486 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16875159 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16875159 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 16875159 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 16875159 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12499050 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 17445831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2705441 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 30552937 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 30882476 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3524929 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 3524929 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 25796146 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9186252 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 4026357 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 26811189 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18390395 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18390395 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 18390395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12657405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11271340 — Biomarker: RAPGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 29504187 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 27599039 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 25409371 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15975977 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8828788 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 8828788 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 28084062 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20938662 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study 11398878 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8584300 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2127076 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 28681205 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8845601 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8845601 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 23748166 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22002336 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11751715 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11751715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2884059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29680006 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 18573839 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 16095053 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10599951 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30784924 — Biomarker: Activated leukocyte cell adhesionmolecule
Type: Predictive Biomarker (PRD)
Genes: ALCAM; MEMD
Study 15741208 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8491498 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30378311 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 30378311 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 12865102 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 10805059 — Biomarker: Amyloid beta peptide (1-40)
Type: Pharmacodynamic Biomarker (PDY)
Genes: APP; A4; AD1
Study 8644690 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 8644690 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27605407 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 16085556 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10707784 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 11836286 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11836286 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10094169 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23906938 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 23906938 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 19728118 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9692412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2468862 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30554386 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30554386 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 27832384 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 25963425 — Biomarker: Dihydrothymine dehydrogenase
Type: Safety Biomarker (SAF)
Genes: DPYD
Study 18038208 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 16839319 — Biomarker: MC3R mRNA
Type: Predictive Biomarker (PRD)
Genes: MC3R
Study 10636260 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25669177 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25669177 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18344711 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 11208501 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 27334434 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 27334434 — Biomarker: SLC2A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A1; GLUT1
Study 9141121 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29047215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18447091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7649339 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 1106204 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 1421390 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29767227 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 25719344 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25719344 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 20869358 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 17030751 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 15895715 — Biomarker: ALAS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALAS2; ALASE; ASB
Study 7699233 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 21633719 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 1790087 — Biomarker: PLAGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLAGL1; LOT1; ZAC
Study 1790087 — Biomarker: ERCC2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MAG; EM9; MGC102762; MGC126218; MGC126219
Study 20579524 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 1816597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23055587 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 15811060 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15811060 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 29726480 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 29726480 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 20670466 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20670466 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17695946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15805229 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7506172 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7506172 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7506172 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31268481 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 21660675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21660675 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 14751651 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3575022 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7974348 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7974348 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 2493869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30668274 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 28526798 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8772223 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 30459099 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26599332 — Biomarker: TLR2
Type: Predictive Biomarker (PRD)
Genes: TIL4; CD282
Study 21182345 — Biomarker: Undetectable plasma HIV RNA
Type: Surrogate Endpoint (SUR)
Study 12535809 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25277543 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19129262 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12684358 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12684358 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12684358 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 12684358 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 12684358 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1524994 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31587925 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29509769 — Biomarker: DPT mRNA
Type: Predictive Biomarker (PRD)
Genes: DPT
Study 18593651 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3989392 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31504118 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 28747330 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 28747330 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 15365277 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27137950 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22192144 — Biomarker: CXCR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR2; IL8RB
Study 20430947 — Biomarker: TNF-related weak inducer of apoptosis
Type: Predictive Biomarker (PRD)
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study 20430947 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 11966765 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 11966765 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30875097 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 30875097 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10451461 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 10451461 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 2141491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2141491 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 695649 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19690349 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15550144 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10404354 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7013510 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29723001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23422754 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19901115 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19901115 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 11079255 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 8844228 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8844228 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 29345398 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22845895 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 27659126 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27659126 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27029553 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT