AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT01607489 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT01009151 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02280369 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00809484 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT00809484 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03596866 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT05786703 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03236675 — Biomarker: EML4 mRNA
Type: Predictive Biomarker (PRD)
Genes: EML4; C2orf2; EMAPL4
Study NCT03236675 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT03236675 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01034605 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study NCT02090036 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study NCT01856868 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study NCT00148109 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00148109 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00503100 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study NCT00503100 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03269916 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT00495105 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04536545 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study NCT01269528 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study NCT03492762 — Biomarker: CCR2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCR2; CMKBR2
Study NCT02724098 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00659178 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study NCT01302860 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study NCT03111511 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT01775124 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT02440945 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02806648 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study NCT03071263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03702231 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study NCT04277182 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study NCT04277182 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03306589 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00001750 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT00973557 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00973557 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT02245633 — Biomarker: ADAMTS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT02245633 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study NCT02484053 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT02843906 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01588873 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study NCT01588873 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00653523 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02010853 — Biomarker: CA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA1
Study NCT03847844 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT02048332 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT02217124 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00001782 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study NCT03510572 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03403582 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03403582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02274571 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT02112136 — Biomarker: PRKD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKD1; PKD; PKD1; PRKCM
Study NCT02112136 — Biomarker: PKD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PKD2; TRPP2
Study NCT02112136 — Biomarker: Uromodulin
Type: Safety Biomarker (SAF)
Genes: UMOD
Study NCT03676075 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study NCT03592667 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00143676 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00143676 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00467285 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03599609 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03599609 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00159692 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04203095 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03593109 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT03593109 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study NCT00358176 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02314780 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study NCT02314780 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT01320059 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03319979 — Biomarker: DHFR mRNA
Type: Predictive Biomarker (PRD)
Genes: DHFR
Study NCT03319979 — Biomarker: DHFR
Type: Safety Biomarker (SAF)
Genes: DHFR1
Study NCT01015560 — Biomarker: CCR2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCR2; CMKBR2
Study NCT00000145 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT05899439 — Biomarker: IFIH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFIH1; MDA5; RH116
Study NCT05899439 — Biomarker: TYK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TYK2
Study NCT06443372 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study NCT04071197 — Biomarker: ATP8B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATP8B1; ATPIC; FIC1; PFIC
Study NCT00005377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00839904 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00113945 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study NCT00113945 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study NCT03505034 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT05170061 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04950452 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study NCT02096601 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study NCT03208777 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study NCT02984202 — Biomarker: NF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF2; SCH
Study NCT00285428 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT04657471 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT00964587 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03927573 — Biomarker: PSCA mRNA
Type: Predictive Biomarker (PRD)
Genes: PSCA; UNQ206/PRO232
Study NCT03057990 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study NCT04610541 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study NCT04782336 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT00204711 — Biomarker: SNAP25 mRNA
Type: Predictive Biomarker (PRD)
Genes: SNAP25; SNAP
Study NCT02919709 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT05661006 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT03146208 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT03146208 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT02587988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01104597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02875886 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00402376 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT04571359 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study NCT02934256 — Biomarker: NF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF2; SCH
Study NCT03629379 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02762695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04125446 — Biomarker: FGR mRNA
Type: Predictive Biomarker (PRD)
Genes: FGR; SRC2
Study NCT02870803 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study NCT00698009 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT01737827 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT00633971 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study NCT03689582 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04206891 — Biomarker: Epithelial cadherin
Type: Predictive Biomarker (PRD)
Genes: CDH1; CDHE; UVO
Study NCT03014076 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03014076 — Biomarker: GP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GP2
Study NCT03014076 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01835457 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01835457 — Biomarker: IL1RN mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RN; IL1F3; IL1RA
Study NCT01835457 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study NCT00003575 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT00003575 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study NCT00003575 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study NCT04039399 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06133400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02103244 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT04294927 — Biomarker: DNMBP mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMBP; ARHGEF36; KIAA1010; TUBA
Study NCT02086604 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study NCT00367250 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00367250 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02338973 — Biomarker: NR2E3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR2E3; PNR; RNR
Study NCT02338973 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT03374527 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04247763 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT05333692 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT02984293 — Biomarker: LILRB5 mRNA
Type: Predictive Biomarker (PRD)
Genes: LILRB5; LIR8
Study NCT03006146 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01244854 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02047903 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02047903 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03016312 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00506259 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study NCT03880292 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04196179 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study NCT02592408 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study NCT03986281 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04619251 — Biomarker: UGT2B17 mRNA
Type: Predictive Biomarker (PRD)
Genes: UGT2B17
Study NCT01852253 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study NCT00152880 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT00679029 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00679029 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT02022995 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02022995 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT02372578 — Biomarker: PDPN mRNA
Type: Predictive Biomarker (PRD)
Genes: PDPN; GP36; PSEC0003; PSEC0025
Study NCT02330406 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01421017 — Biomarker: TLR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR7; UNQ248/PRO285
Study NCT02401685 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT01711073 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT02537002 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT04678089 — Biomarker: TMEM37 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMEM37; PR
Study NCT04678089 — Biomarker: RANGAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RANGAP1; KIAA1835; SD
Study NCT02732457 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00701532 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study NCT01681888 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study NCT04750785 — Biomarker: CHM mRNA
Type: Predictive Biomarker (PRD)
Genes: CHM; REP1; TCD
Study NCT02938091 — Biomarker: LIPC mRNA
Type: Predictive Biomarker (PRD)
Genes: LIPC; HTGL
Study NCT00557765 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT01069692 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02842320 — Biomarker: IL1RAP mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RAP; C3orf13; IL1R3
Study NCT01052220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04447573 — Biomarker: TNFRSF17 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF17; BCM; BCMA
Study NCT04675385 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT02904031 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03573934 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT03932877 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study NCT03461003 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03458936 — Biomarker: RRAD mRNA
Type: Predictive Biomarker (PRD)
Genes: RRAD; RAD
Study NCT02648490 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03552432 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study NCT00551590 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT00551590 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT03958383 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT03781050 — Biomarker: STK11 mRNA
Type: Predictive Biomarker (PRD)
Genes: STK11; LKB1; PJS
Study NCT00690612 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00607685 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT03432507 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04034823 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04072042 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study NCT04397991 — Biomarker: TTN mRNA
Type: Predictive Biomarker (PRD)
Genes: TTN
Study NCT01325376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04082546 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study NCT02649140 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study NCT02663518 — Biomarker: CD47 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD47; MER6
Study NCT00353522 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study NCT02856477 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study NCT05379478 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT00626132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00003601 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study NCT03176823 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study NCT03176823 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00559390 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02989701 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT02989701 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01611805 — Biomarker: CCR9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR9; GPR28
Study NCT03421626 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT03421626 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT01583699 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study NCT00405925 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00005270 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01498159 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00305331 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study NCT03545503 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01683656 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01075802 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study NCT01075802 — Biomarker: CYP2D6
Type: Safety Biomarker (SAF)
Genes: CPD6; P450-DB1; CYP2D; P450C2D
Study NCT03704246 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study NCT01744392 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05468892 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00528736 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study NCT01556191 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01556191 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01556191 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study NCT01556191 — Biomarker: Ribonucleoside-diphosphate reductase large subunit
Type: Predictive Biomarker (PRD)
Genes: RRM1; RR1
Study NCT01151410 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03642925 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT02586025 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06722612 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02944136 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1