AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04140838 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study NCT04140838 — Biomarker: FKBP5 mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: FKBP5; AIG6; FKBP51
Study NCT04140838 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02000986 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02395666 — Biomarker: ODC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ODC1
Study NCT04449601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03947996 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02330965 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study NCT00552214 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT03904810 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03904810 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03904810 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT03904810 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04223583 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study NCT00877110 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT03516292 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study NCT03642015 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04516486 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT04516486 — Biomarker: C1QL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: C1QL1; C1QRF; CRF; CTRP14
Study NCT04603612 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT04603612 — Biomarker: ANXA10 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANXA10; ANX14
Study NCT04603612 — Biomarker: UPK1B mRNA
Type: Predictive Biomarker (PRD)
Genes: UPK1B; TSPAN20
Study NCT04603612 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study NCT04603612 — Biomarker: IGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF2; PP1446
Study NCT01925274 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT01925274 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study NCT00559754 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00559754 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00559754 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study NCT00559754 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT01543971 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT00145171 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03634644 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study NCT02150369 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT01792271 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study NCT03997747 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT03997747 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study NCT02219035 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study NCT02219035 — Biomarker: ADAMTS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT03238144 — Biomarker: MYRF mRNA
Type: Predictive Biomarker (PRD)
Genes: MYRF; C11orf9; KIAA0954; MRF
Study NCT04506749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00079768 — Biomarker: CD52 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD52; CDW52; HE5
Study NCT03130608 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT00547235 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study NCT02127047 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT02127047 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT03801083 — Biomarker: BTC mRNA
Type: Predictive Biomarker (PRD)
Genes: BTC
Study NCT02700022 — Biomarker: Aurora kinase A
Type: Predictive Biomarker (PRD)
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT02787551 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT03880279 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT00591266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01135212 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04408131 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT02207400 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study NCT00512967 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT02084095 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT05352373 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02368782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00761371 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04276337 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04276337 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT04276337 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study NCT00977769 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02338401 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study NCT03166839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02497833 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study NCT02280538 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT03629210 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03701802 — Biomarker: CD101 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD101; EWI101; IGSF2; V7
Study NCT02130024 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT02130024 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02130024 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT03219268 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03659955 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT01982578 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study NCT00810732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03979131 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study NCT03227328 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study NCT03227328 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT03951233 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03951233 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT00005490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02636127 — Biomarker: CX3CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CX3CR1; CMKBRL1; GPR13
Study NCT00195572 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study NCT02423811 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study NCT02423811 — Biomarker: CD24 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD24; CD24A
Study NCT02423811 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study NCT02423811 — Biomarker: ABCG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study NCT02423811 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT04443387 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study NCT02442206 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT01423019 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01891110 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01182818 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00002637 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT00002637 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT01874743 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study NCT01874743 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT01874743 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01874743 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study NCT00595465 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT02848599 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02848599 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT02479269 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00331864 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT00331864 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT03772951 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT03772951 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT02849886 — Biomarker: CASP9
Type: Predictive Biomarker (PRD)
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study NCT00119990 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03571308 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT03697980 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01062451 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT02254083 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00580996 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03098355 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study NCT03098355 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT03098355 — Biomarker: CASP9
Type: Predictive Biomarker (PRD)
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study NCT03098355 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT03644680 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT00887939 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study NCT02583542 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT06193525 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT00175695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02429427 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT03274232 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT00807131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05100758 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT05100758 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT05100758 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study NCT00528827 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00876876 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study NCT01865188 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02777710 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02777710 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02777710 — Biomarker: CSF1R mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF1R; FMS
Study NCT04315025 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT03919253 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03875768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00315146 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study NCT00176787 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study NCT01144208 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00179543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02768948 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study NCT02147184 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02268617 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study NCT03761693 — Biomarker: ACADM mRNA
Type: Predictive Biomarker (PRD)
Genes: ACADM
Study NCT02900612 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02900612 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03709290 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study NCT03709290 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study NCT03984955 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT02626767 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02626767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02734082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01497717 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03547258 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study NCT00082186 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT03442088 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study NCT04027179 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02617888 — Biomarker: Gamma-Histone H2AX
Type: Pharmacodynamic Biomarker (PDY)
Genes: H2AX; H2AFX
Study NCT00185835 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00185835 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00757120 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study NCT03064230 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03873610 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study NCT03873610 — Biomarker: NF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF2; SCH
Study NCT03605212 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study NCT01921270 — Biomarker: OMD mRNA
Type: Predictive Biomarker (PRD)
Genes: OMD; SLRR2C; UNQ190/PRO216
Study NCT06468761 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT00006334 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00616564 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00616564 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT01609231 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT02366988 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study NCT00493532 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01067066 — Biomarker: TPI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPI1; TPI
Study NCT01480531 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04193358 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT04151173 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT03090438 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study NCT03983993 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01161303 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00586651 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study NCT02401542 — Biomarker: FGFR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR3; JTK4
Study NCT04306900 — Biomarker: ENTPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ENTPD1; CD39
Study NCT02108782 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03104322 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT01355055 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03814473 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00224848 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00224848 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02004600 — Biomarker: COL7A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL7A1
Study NCT04822480 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04357782 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04357782 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study NCT00005673 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT01303783 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00302263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01008176 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01008176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01008176 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT01389271 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT02024555 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT03653195 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study NCT03866226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02685046 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT02685046 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study NCT03459261 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03459261 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03459261 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT03459261 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study NCT03459261 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study NCT03207204 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study NCT03207204 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study NCT01540565 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT01540565 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study NCT03177603 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT03177603 — Biomarker: RAS peptides
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01424709 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT01424709 — Biomarker: Ribonucleoside-diphosphate reductase large subunit
Type: Predictive Biomarker (PRD)
Genes: RRM1; RR1
Study NCT00736814 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study NCT00736814 — Biomarker: Ribonucleoside-diphosphate reductase large subunit
Type: Predictive Biomarker (PRD)
Genes: RRM1; RR1
Study NCT03141099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02167464 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study NCT02167464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00239304 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02837276 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT04439149 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study NCT01351142 — Biomarker: EIF2AK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EIF2AK2; PKR; PRKR
Study NCT01351142 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study NCT00371605 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10