AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 16415095 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 8799095 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31477280 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 9088584 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 31390907 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21724681 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 21724681 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 21724681 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21724681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21724681 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21724681 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 20605316 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 11057103 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19853704 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10421972 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2091171 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 31810731 — Biomarker: CALD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CALD1; CAD; CDM
Study 16449866 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25921849 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 21224369 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16868887 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16868887 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16868887 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 26951352 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23137503 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 23137503 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 31271585 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 2920497 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23935129 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 23935129 — Biomarker: CYP2R1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2R1
Study 17196132 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17196132 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15333417 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 15333417 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8388285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29576347 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11032592 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22893497 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22893497 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10642363 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1380721 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31444036 — Biomarker: GLRB mRNA
Type: Predictive Biomarker (PRD)
Genes: GLRB
Study 26775268 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 26775268 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 20200383 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 11836283 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 31578073 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 17094981 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 17094981 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17094981 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 26066736 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 19186958 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11260410 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8045978 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 8045978 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8045978 — Biomarker: POMC mRNA
Type: Predictive Biomarker (PRD)
Genes: POMC
Study 23615640 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 23615640 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23615640 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23615640 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15513442 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 29420150 — Biomarker: Succinate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: SDHD
Study 27716246 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27716246 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 20691830 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18240203 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14673036 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10069525 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 10069525 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 31359519 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31359519 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18160686 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27041263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23715407 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23221660 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21374895 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 9013219 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8736043 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 26568566 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26568566 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 26568566 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 22115984 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 22115984 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22115984 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 22115984 — Biomarker: Angiopoietin-1
Type: Monitoring Biomarker (MOI)
Genes: ANGPT1; KIAA0003
Study 22115984 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 22115984 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22115984 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19237716 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 18070474 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 11560871 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 11560871 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 27031165 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9892586 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 31704264 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 31826005 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28060837 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 28060837 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 28060837 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 20445533 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 20445533 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18349171 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10574592 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 10574592 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 31492716 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15921933 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 28881355 — Biomarker: CTSL mRNA
Type: Predictive Biomarker (PRD)
Genes: CTSL; CTSL1
Study 28881355 — Biomarker: GSK3B mRNA
Type: Predictive Biomarker (PRD)
Genes: GSK3B
Study 28881355 — Biomarker: MED12 mRNA
Type: Predictive Biomarker (PRD)
Genes: MED12; ARC240; CAGH45; HOPA; KIAA0192; TNRC11; TRAP230
Study 28881355 — Biomarker: LAMC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMC2; LAMB2T; LAMNB2
Study 22307566 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 17454195 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 10100275 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 25675650 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 23306000 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19058332 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 29800784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18796517 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 18796517 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 18796517 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12866745 — Biomarker: FGA mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGA
Study 27377675 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 31125079 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31125079 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 31125079 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29141858 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 29141858 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19926748 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22129522 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22129522 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6117392 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31217962 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20190646 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10086330 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 10086330 — Biomarker: CYP2E1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2E1; CYP2E
Study 10086330 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 10086330 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31952174 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23670958 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29501386 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25030039 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8722435 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8722435 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 1888693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31043095 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16389162 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16389162 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16389162 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30209017 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 27387743 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 10401802 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25407688 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21353462 — Biomarker: AWAT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AWAT2; DC4; DGAT2L4; MFAT; WS
Study 19692317 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 20118792 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20118792 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15676092 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25469804 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 25469804 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 8246577 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 8187026 — Biomarker: DDR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 8187026 — Biomarker: TAC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAC1; NKA; NKNA; TAC2
Study 6510453 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27770155 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12510800 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9049514 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12873574 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 29574075 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 29574075 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21858807 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 30768393 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 25727941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10612322 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10612322 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1647183 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1647183 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27484801 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 10543484 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 8912225 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19747623 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 17210735 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 4041332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27974693 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 15202794 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 2355813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16731290 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3963032 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27281061 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20175977 — Biomarker: TTMP mRNA
Type: Predictive Biomarker (PRD)
Genes: TTMP; C3orf52
Study 12524662 — Biomarker: GHR mRNA
Type: Predictive Biomarker (PRD)
Genes: GHR
Study 12524662 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12524662 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9031710 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10146939 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6835887 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2005231 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 29910030 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29910030 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29910030 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31050034 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 8039040 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8039040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23712109 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 23712109 — Biomarker: PTGDS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGDS; PDS
Study 21852403 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 3933736 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21081251 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 24947595 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 19459773 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15526045 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15526045 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15526045 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11724652 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 7895178 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28739134 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 20801941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9475575 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7624490 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 2196359 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23033246 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22470031 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28771018 — Biomarker: COPE mRNA
Type: Predictive Biomarker (PRD)
Genes: COPE
Study 27973414 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23908187 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 22749176 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22749176 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15540759 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21029642 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11341172 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 30440913 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 25180279 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19093057 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 16280177 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23373793 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12556074 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 12556074 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 12556074 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 7726669 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31714636 — Biomarker: HMGCR mRNA
Type: Predictive Biomarker (PRD)
Genes: HMGCR
Study 31714636 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 31714636 — Biomarker: NPC1L1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NPC1L1
Study 31714636 — Biomarker: APOB mRNA
Type: Predictive Biomarker (PRD)
Genes: APOB
Study 31714636 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26872721 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 26872721 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)