AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 27927683 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25765698 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23340440 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 23340440 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19386741 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 23855301 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 17467914 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17467914 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15179174 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 7872714 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 3337013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3337013 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15917194 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 12789036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9012300 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 2864857 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30753892 — Biomarker: miR-22
Type: Safety Biomarker (SAF)
Genes: MIR22
Study 30753892 — Biomarker: miR-19a
Type: Predictive Biomarker (PRD)
Genes: MIR19A
Study 1632390 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28795387 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 16361173 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7923305 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11811084 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 25830326 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 24246588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24246588 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16190390 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 10527998 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 7667814 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31274775 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31274775 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 31274775 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 17902062 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 7950508 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7950508 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25020104 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 28478399 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 28478399 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23563576 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21593649 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 21593649 — Biomarker: SYN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SYN1
Study 27734127 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20977851 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9456256 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9456256 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8903614 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11466696 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 10800872 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8822458 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 28146063 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23800784 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21297523 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 16964830 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9013400 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 3902238 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24858423 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15912390 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15912390 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2550244 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2550244 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28859672 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 28859672 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10902934 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 30699842 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 22694045 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 1501561 — Biomarker: OSM mRNA
Type: Predictive Biomarker (PRD)
Genes: OSM
Study 30120772 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19328269 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16874150 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10669155 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 10669155 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10669155 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 29350831 — Biomarker: MAS1L mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1L; MRG
Study 16052841 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10365650 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 10365650 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 10365650 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 6117682 — Biomarker: RFC1
Type: Safety Biomarker (SAF)
Genes: A1; PO-GA; RFC140; MHCBFB
Study 29884593 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18163509 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29753732 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29753732 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29753732 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29753732 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 29753732 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29753732 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29753732 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 29753732 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 25342100 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 20033066 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 9737555 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24280475 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 24280475 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24280475 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21691756 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19112586 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27323611 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 27323611 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 27323611 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27323611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24777981 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20600512 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20600512 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9920948 — Biomarker: TNFR1B
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 9920948 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15987428 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 15987428 — Biomarker: CYP1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1B1
Study 9464197 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 7842768 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22000747 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 20153888 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1643679 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 25185362 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16753318 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 23733374 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19015346 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 19015346 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 17210593 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9358616 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 24561488 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 20647773 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 15770976 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23501476 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19266265 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19266265 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10649155 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10649155 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28660498 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 21512399 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 31808709 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 26564598 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 26564598 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 26564598 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26564598 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24285618 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 16236039 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 7548979 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30777086 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 17530638 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 17530638 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17530638 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 15238592 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15238592 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3651528 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 11194979 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2981088 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26142345 — Biomarker: CHRNA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA5; NACHRA5
Study 15365622 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26416458 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 26416458 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23840296 — Biomarker: NR1I2
Type: Predictive Biomarker (PRD)
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 23840296 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 23840296 — Biomarker: NR1I2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1I2; PXR
Study 9024268 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9024268 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14637136 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 10757852 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29558953 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29558953 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22320186 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 22320186 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 12856480 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 12856480 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29671280 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 11795752 — Biomarker: BAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAK1; BAK; BCL2L7; CDN1
Study 31495389 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28130475 — Biomarker: ESR1
Type: Predictive Biomarker (PRD)
Genes: NR3A1; Era; ER-alpha
Study 19959692 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 125133 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28286189 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 17538539 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17538539 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11688766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29131285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16035144 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10037246 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 1823750 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31688513 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28684276 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 9513910 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 7652038 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 356078 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24814691 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 7826567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7826567 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30805908 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25675201 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 25675201 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18937820 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 7874855 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26354729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19017467 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24714415 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20369705 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 15687530 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27055107 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16093971 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 10969304 — Biomarker: Auditory steady-state response
Type: Pharmacodynamic Biomarker (PDY)
Study 20537151 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18662628 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 1889023 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30682445 — Biomarker: REG3A mRNA
Type: Predictive Biomarker (PRD)
Genes: REG3A; HIP; PAP; PAP1
Study 30682445 — Biomarker: TNC mRNA
Type: Predictive Biomarker (PRD)
Genes: TNC; HXB
Study 30682445 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 22569029 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17915162 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11491175 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 24736628 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24736628 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22581064 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22581064 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22581064 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 1693496 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20015525 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20015525 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6367617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26901812 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25281437 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22458343 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20147463 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 10410825 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28027638 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28027638 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25056567 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 22268365 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 22268365 — Biomarker: Hepatitis A virus cellular receptor 1
Type: Safety Biomarker (SAF)
Genes: HAVCR1; KIM1; TIM1; TIMD1
Study 24457404 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 20880335 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 9894374 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23297680 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 1681847 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 1681847 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16116005 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28968870 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7930740 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 16678893 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1580290 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1580290 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31408467 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22873117 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31368518 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 21704360 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 22090467 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22090467 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 22090467 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)