AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 22830016 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 7768497 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 24382970 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16673014 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1679661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18635497 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10627728 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10627728 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2537560 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2537560 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20438562 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 15988144 — Biomarker: RUNX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX1; AML1; CBFA2
Study 15988144 — Biomarker: RUNX1T1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study 2505642 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28639445 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 28639445 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16378790 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31476826 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 1282602 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1282602 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22790403 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22790403 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 22790403 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 22790403 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22790403 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 22790403 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19932167 — Biomarker: MUTYH mRNA
Type: Predictive Biomarker (PRD)
Genes: MUTYH; MYH
Study 19932167 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 17380213 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17380213 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15674307 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20632462 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20632462 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 20632462 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 8227917 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8227917 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23443332 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 23147689 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23147689 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23784346 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 25677679 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23305631 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15961340 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31896134 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 28324167 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18495735 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18495735 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18495735 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18495735 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16343085 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12475462 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 8944402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23648056 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 30720733 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 19018087 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 29959802 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 20947383 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18536386 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 15023658 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 26903143 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 21937520 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20040875 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 12028174 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 7879787 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7879787 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30635159 — Biomarker: NAGLU mRNA
Type: Predictive Biomarker (PRD)
Genes: NAGLU; UFHSD1
Study 19099160 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30120476 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 21211299 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10988281 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30523133 — Biomarker: ACAD8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAD8; ARC42; IBD
Study 15292314 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 11133904 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 29351791 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 14673725 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28921841 — Biomarker: L1CAM mRNA
Type: Predictive Biomarker (PRD)
Genes: L1CAM; CAML1; MIC5
Study 28921841 — Biomarker: Insulin receptor substrate 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IRS1
Study 26499146 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21325456 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 21325456 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21325456 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 21325456 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15040783 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15040783 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11828273 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27814282 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 27814282 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 25948027 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22954665 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29133605 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 29133605 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28195970 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28195970 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 23839771 — Biomarker: CSMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSMD1; KIAA1890; UNQ5952/PRO19863
Study 21447413 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22562554 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 16182674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8932548 — Biomarker: NAPA mRNA
Type: Predictive Biomarker (PRD)
Genes: NAPA; SNAPA
Study 6732679 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 6732679 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 31984508 — Biomarker: GDNF mRNA
Type: Predictive Biomarker (PRD)
Genes: GDNF
Study 31984508 — Biomarker: FGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF2; FGFB
Study 31984508 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20398352 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20398352 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 17357850 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 8412202 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 23527715 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16947783 — Biomarker: AMPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMPD1
Study 16947783 — Biomarker: ATIC mRNA
Type: Predictive Biomarker (PRD)
Genes: ATIC; PURH; OK/SW-cl.86
Study 16947783 — Biomarker: ITPA mRNA
Type: Predictive Biomarker (PRD)
Genes: ITPA; C20orf37; My049; OK/SW-cl.9
Study 16947783 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 16947783 — Biomarker: MTRR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTRR
Study 30194992 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 30194992 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC
Study 30194992 — Biomarker: CCL18 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 30194992 — Biomarker: CCL26 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL26; SCYA26; UNQ216/PRO242
Study 30194992 — Biomarker: ICOS mRNA
Type: Predictive Biomarker (PRD)
Genes: ICOS; AILIM
Study 30194992 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 30194992 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 30194992 — Biomarker: LORICRIN mRNA
Type: Predictive Biomarker (PRD)
Genes: LORICRIN; LOR; LRN
Study 22356267 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 22356267 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22356267 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 15895312 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 22744627 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17461735 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2066757 — Biomarker: MIOS mRNA
Type: Predictive Biomarker (PRD)
Genes: MIOS
Study 31347669 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 9315984 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 3533203 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 21458721 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 14513073 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14513073 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10904510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3712636 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3712636 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3712636 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31596971 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25583272 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17205821 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 25390761 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25390761 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6774674 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26317662 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 20725056 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3621989 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22079797 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 22079797 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22079797 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20044087 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 20044087 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 20044087 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 20044087 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 10516451 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10150489 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 27400374 — Biomarker: Cadherin-13
Type: Predictive Biomarker (PRD)
Genes: CDH13; CDHH
Study 27400374 — Biomarker: TFPI2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI2
Study 27400374 — Biomarker: FSTL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FSTL1; FRP
Study 24766239 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17233861 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 15782501 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 12149108 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12149108 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 27061732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25792627 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27515331 — Biomarker: TNFRSF17 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF17; BCM; BCMA
Study 22543981 — Biomarker: ADRA2C mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRA2C; ADRA2L2; ADRA2RL2
Study 22543981 — Biomarker: ADRB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB1; ADRB1R; B1AR
Study 22543981 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 22543981 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19556358 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 17402274 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17402274 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15613923 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 21989146 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 23176073 — Biomarker: MAOB mRNA
Type: Predictive Biomarker (PRD)
Genes: MAOB
Study 20885016 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20885016 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24412053 — Biomarker: miR-9
Type: Safety Biomarker (SAF)
Study 24412053 — Biomarker: miR-21
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR21
Study 24412053 — Biomarker: miR-31
Type: Predictive Biomarker (PRD)
Genes: MIR31
Study 24412053 — Biomarker: miR-34a
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR34A
Study 24412053 — Biomarker: miR-137
Type: Safety Biomarker (SAF)
Genes: MIR137
Study 21895939 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 3469982 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3469982 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 3469982 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31629353 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16619217 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 10966839 — Biomarker: GYPC mRNA
Type: Predictive Biomarker (PRD)
Genes: GYPC; GLPC; GPC
Study 22051419 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 8683251 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 30383670 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30383670 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30383670 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9199818 — Biomarker: REG3A mRNA
Type: Predictive Biomarker (PRD)
Genes: REG3A; HIP; PAP; PAP1
Study 9199818 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 9199818 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31131629 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 31131629 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28842727 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23897585 — Biomarker: SFTPB mRNA
Type: Predictive Biomarker (PRD)
Genes: SFTPB; SFTP3
Study 15315111 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11692092 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 28482877 — Biomarker: Epiregulin
Type: Safety Biomarker (SAF)
Genes: EREG
Study 17907228 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 17907228 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17907228 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 17907228 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 6995513 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25833066 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10469856 — Biomarker: Growth/differentiation factor 15
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 6577782 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30520691 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 16488299 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8409070 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21903895 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 21903895 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 16324850 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 1827086 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28242040 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 28242040 — Biomarker: MAOA mRNA
Type: Predictive Biomarker (PRD)
Genes: MAOA
Study 28242040 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 25762461 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 23650397 — Biomarker: SGK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SGK1; SGK
Study 9028540 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29920123 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21310284 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 28400200 — Biomarker: VIM mRNA
Type: Predictive Biomarker (PRD)
Genes: VIM
Study 14987306 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 8697308 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6141724 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26530743 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 24084072 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24084072 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 21961181 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 21961181 — Biomarker: SAT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT2; SSAT2
Study 10895372 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 25262434 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25262434 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15908647 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 12935395 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 11214769 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6343656 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31322833 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 20823391 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15805799 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 22231536 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 15110130 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)