AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 15861352 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10196731 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31513088 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21297287 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1531952 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26987589 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16146472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11246561 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11246561 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 11246561 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 9566100 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7827399 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 12540551 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 28514347 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 25560575 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25560575 — Biomarker: DEF6 mRNA
Type: Predictive Biomarker (PRD)
Genes: DEF6; IBP
Study 25560575 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23621161 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 6356628 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25697725 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 21434341 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 21434341 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 21434341 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21434341 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 9094151 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 3510088 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30054920 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 30054920 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30054920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25223724 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27804174 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 7391628 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 26721134 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 26721134 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 22405557 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 16311300 — Biomarker: Proliferation marker protein Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67
Study 16311300 — Biomarker: CASP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CASP3; CPP32
Study 16311300 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 16311300 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22535748 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 20685495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16503317 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16503317 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16503317 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12094185 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31483891 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21226820 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 21226820 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23337366 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20088416 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 20088416 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 7634504 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26343717 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 26343717 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23835687 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 10229297 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 3892794 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12888137 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2060557 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19816415 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10770345 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8914032 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8914032 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27788949 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 17272375 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31821506 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27102504 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17030687 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12747268 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 12747268 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8166061 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31792945 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 28400411 — Biomarker: FAU mRNA
Type: Predictive Biomarker (PRD)
Genes: FAU
Study 23519371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15289018 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 30659035 — Biomarker: ZDHHC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZDHHC2; REAM; REC; ZNF372
Study 30101851 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 30101851 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 25316503 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 2654171 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 9431839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31174535 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31174535 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28834553 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 23343686 — Biomarker: CFI mRNA
Type: Predictive Biomarker (PRD)
Genes: CFI; IF
Study 14713761 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 14713761 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 14713761 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 18955670 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 12795786 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 10969261 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 8771109 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28916304 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 18514906 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18514906 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12669270 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15754237 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28658126 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15379416 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 15379416 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15379416 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16924985 — Biomarker: PDXP mRNA
Type: Predictive Biomarker (PRD)
Genes: PDXP; CIN; PLP; PLPP
Study 15631892 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 15631892 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 15631892 — Biomarker: Complement C4
Type: Monitoring Biomarker (MOI)
Study 10092996 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10092996 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 10092996 — Biomarker: Peroxisome proliferator-activated receptor delta
Type: Safety Biomarker (SAF)
Genes: PPARD
Study 31568675 — Biomarker: AKR1C3 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKR1C3; DDH1; HSD17B5; KIAA0119; PGFS
Study 31568675 — Biomarker: 40S ribosomal protein S6
Type: Predictive Biomarker (PRD)
Genes: RPS6; OK/SW-cl.2
Study 31568675 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 25189222 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 25851052 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 20400652 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 20067974 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 15325831 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 9605982 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 30592963 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16131698 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 16131698 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16131698 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 17702654 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17561350 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 9654535 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 30589514 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 28752209 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 28752209 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28752209 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9283534 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 30587618 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 28862770 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16166818 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22375890 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20584695 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 10395842 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10395842 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 29609113 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 20504911 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 20504911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12003176 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12003176 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22245162 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22245162 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10379016 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30728339 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18004131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10202741 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25922302 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 23350696 — Biomarker: Zinc finger protein GLI1
Type: Predictive Biomarker (PRD)
Genes: GLI1; GLI
Study 19629292 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11511435 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9612361 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30929275 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 28960230 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25583412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26186566 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26186566 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19247655 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 15316165 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 3838401 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31612309 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31612309 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31612309 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 29969520 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study 29969520 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27287235 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29056008 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23809140 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15486377 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8320604 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 22234020 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17585031 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 17585031 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 9024174 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8843231 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10394407 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 8871870 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10585796 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29959901 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23789215 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11015169 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2580182 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30046837 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30046837 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18562739 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 386913 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 26967821 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 11889011 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10077394 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 10077394 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31284844 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25825410 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 25825410 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24642379 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22786569 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22786569 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 20012639 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12399289 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7477218 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2155751 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 7250475 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 27692491 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 16281465 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 1382217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3003305 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27848017 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 11351935 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 29549523 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28207287 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25867422 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21036772 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21036772 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10863716 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24709712 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 24709712 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 22416821 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22416821 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 22416821 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 9380238 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29874654 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 29874654 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 29874654 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29874654 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 12652226 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 2111249 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7457415 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16371019 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 16371019 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 30971593 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 30971593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11860948 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 16384692 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8857476 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1346790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31662555 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 15037536 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15037536 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15037536 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26797134 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26797134 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 15568599 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30672212 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30672212 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27336903 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27336903 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 24398786 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 17902730 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA