AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 25219639 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 25219639 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22910287 — Biomarker: ID3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ID3; 1R21; BHLHB25; HEIR1
Study 10640975 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 3330031 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18729245 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10340912 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 23859530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31665912 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study 17414229 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 21163722 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 14678008 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 2519937 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28624096 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28624096 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28624096 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23426718 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23426718 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23426718 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 23426718 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 12696562 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 7075649 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14669031 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14669031 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 22381072 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17204566 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16360356 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16360356 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9474617 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 7640234 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 28111966 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9058626 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9058626 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 29206647 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11815513 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 6118716 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27863480 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2107581 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30782027 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30269276 — Biomarker: ABCC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC3; CMOAT2; MLP2; MRP3
Study 30269276 — Biomarker: ABCC3
Type: Safety Biomarker (SAF)
Genes: MRP3; cMOAT2; EST90757; MLP2; MOAT-D
Study 30269276 — Biomarker: GGH mRNA
Type: Predictive Biomarker (PRD)
Genes: GGH
Study 30269276 — Biomarker: SLC46A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC46A1; G21; HCP1; PCFT
Study 30269276 — Biomarker: SLC19A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC19A1; FLOT1; RFC1
Study 21923839 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 15026873 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11675056 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25609231 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 26951379 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 24702886 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 12144817 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 18799365 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 17304525 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 15490824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9058440 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9058440 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9058440 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 29912844 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 24627290 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 16364831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10333097 — Biomarker: MAEA mRNA
Type: Predictive Biomarker (PRD)
Genes: MAEA; EMP; HLC10; PIG5
Study 10333097 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 2031819 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17531926 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 17531926 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17531926 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11684821 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 30655639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30655639 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18955451 — Biomarker: KIT
Type: Predictive Biomarker (PRD)
Genes: CD117; SCFR; C-Kit
Study 30724660 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30724660 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 30724660 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25912588 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23015654 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 15824468 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11523669 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9629947 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 24258498 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 24258498 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 24258498 — Biomarker: JAK2
Type: Predictive Biomarker (PRD)
Genes: JTK10
Study 24258498 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 14757326 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 9709744 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 3135010 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23725681 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 19878097 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 3071597 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 3071597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25873213 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25873213 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21425570 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8037337 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24015263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21327798 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15056989 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10028949 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10028949 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10028949 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21868743 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 21868743 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 21868743 — Biomarker: MAEA mRNA
Type: Predictive Biomarker (PRD)
Genes: MAEA; EMP; HLC10; PIG5
Study 20200926 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 7756099 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21482635 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 21482635 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 3752350 — Biomarker: LHB mRNA
Type: Predictive Biomarker (PRD)
Genes: LHB
Study 23863086 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22042952 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 25786714 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 9129064 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29490294 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 27957487 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 16199244 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 16199244 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 3936085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28599060 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 28599060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26975739 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 28749177 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25074436 — Biomarker: S100A12 mRNA
Type: Predictive Biomarker (PRD)
Genes: S100A12
Study 25074436 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 23829576 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21435016 — Biomarker: SLA mRNA
Type: Predictive Biomarker (PRD)
Genes: SLA; SLAP; SLAP1
Study 8977634 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 8977634 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 1418304 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24394343 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 15804153 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12126042 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25942474 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 22784287 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22784287 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22784287 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 22784287 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22784287 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 19960971 — Biomarker: Osteopontin
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SPP1; BNSP; OPN; PSEC0156
Study 27733248 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27733248 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20171784 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 14694042 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 28380132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9317068 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 27433065 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 24788377 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10357730 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10357730 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8770627 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1963191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1963191 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15771277 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9667257 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 9667257 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2687193 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17639095 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 17639095 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 17639095 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 17639095 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 1703598 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 1703598 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1703598 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 29985679 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 22247720 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22247720 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11158416 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 27513822 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23672928 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 23672928 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 23672928 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 12526313 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9395275 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19491335 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9438777 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22790107 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 10232438 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 10232438 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1909086 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29958706 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 29958706 — Biomarker: CCR2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCR2; CMKBR2
Study 29958706 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 29958706 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 29958706 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 29958706 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 19176240 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1827006 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21303402 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 21303402 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 19800722 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19800722 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12738464 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29568771 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29568771 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22442168 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 22442168 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 18706998 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 11039260 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 6394349 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6394349 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 23776431 — Biomarker: PDXP mRNA
Type: Predictive Biomarker (PRD)
Genes: PDXP; CIN; PLP; PLPP
Study 31551206 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17389707 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 17389707 — Biomarker: PDE3B mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE3B
Study 17389707 — Biomarker: UCP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP2; SLC25A8
Study 15466769 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27200393 — Biomarker: RHOJ mRNA
Type: Predictive Biomarker (PRD)
Genes: RHOJ; ARHJ; RASL7B; RHOI; TCL
Study 22330964 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9880379 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1771216 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 31977634 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28855077 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 28855077 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28855077 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26159458 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 26159458 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 19329835 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11444081 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31348334 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 28524025 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28524025 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28524025 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 30395878 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30395878 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15635849 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 9205634 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27686002 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 18485668 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18485668 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29122253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15599677 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11310517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9636952 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2765272 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27888416 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 23759474 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 21683485 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21683485 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23650301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)