AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24187095 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 25712760 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25712760 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 14698860 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 8339033 — Biomarker: ABCD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCD1; ALD
Study 24108237 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22287494 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 18164245 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3923833 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 23670305 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 27271657 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19793213 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 15066925 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 7534838 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7534838 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 17668562 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17668562 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 9586886 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7774334 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 28634748 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21122391 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study 9211627 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27589695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24160223 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16798303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27562743 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23736923 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23736923 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23736923 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 23736923 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 12716796 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12716796 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 9426079 — Biomarker: DDR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 9426079 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 30930132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12548304 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 12548304 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12548304 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28069279 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 28069279 — Biomarker: LYN mRNA
Type: Predictive Biomarker (PRD)
Genes: LYN; JTK8
Study 12941995 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11055467 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11055467 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27988356 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17926617 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 11204938 — Biomarker: ELK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELK3; NET; SAP2
Study 9603128 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 7530064 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 23743809 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21649813 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 18319586 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 29223479 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29223479 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 2543201 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4853634 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26437613 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 20346304 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31190621 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 31190621 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 31390590 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 15074084 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 2822879 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29862395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11121919 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9125681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3689613 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 28620941 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23786500 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3931943 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 27368012 — Biomarker: FBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBP1; FBP
Study 25053182 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30965275 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 30965275 — Biomarker: MBTPS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBTPS1; KIAA0091; S1P; SKI1
Study 30965275 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 26091197 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 23435530 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 11061530 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11061530 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11061530 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2573364 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 26049123 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16769471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12897375 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 2868573 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27863207 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 24190902 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24390887 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22848481 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22848481 — Biomarker: Plasma DNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19276983 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15359921 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study 11176735 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11176735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9608581 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 15486848 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26897130 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 25690407 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24136138 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20504977 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20504977 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20504977 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20504977 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15717460 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6342165 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 6342165 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12393661 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 12393661 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12393661 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 10214857 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24170325 — Biomarker: PLXNA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 2533187 — Biomarker: CARD16 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARD16; COP; COP1
Study 2533187 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 972133 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31174403 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 23588240 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 15618599 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10360370 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24354651 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 23001587 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8004839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25665096 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19413407 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 17892999 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14706203 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 14706203 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 11685384 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 31313547 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27928454 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 27928454 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27928454 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 19624730 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18370544 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29071946 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19563287 — Biomarker: TKT mRNA
Type: Predictive Biomarker (PRD)
Genes: TKT
Study 7797808 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2150640 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 533742 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30829609 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 15347773 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 15347773 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 2789447 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6721127 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 25084070 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 20506504 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 12547850 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12547850 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8618160 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20723636 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12358339 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 23416800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19568709 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 14753131 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 29909091 — Biomarker: UGT1A1
Type: Safety Biomarker (SAF)
Genes: UGT1A
Study 23833854 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18756940 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27378823 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16168630 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 12689685 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 12689685 — Biomarker: CYP19A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 12689685 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12689685 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18039987 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18039987 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30150014 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24679550 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24679550 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8878253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22466910 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9204220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7957457 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26585988 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study 26585988 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25581656 — Biomarker: GRIK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIK1; GLUR5
Study 10700443 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 27226182 — Biomarker: AIP mRNA
Type: Predictive Biomarker (PRD)
Genes: AIP; XAP2
Study 27226182 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22325903 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 17418730 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12572376 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 23298374 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 21572305 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19620495 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19620495 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19620495 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 19620495 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 9165550 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 1375485 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29703793 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 19261825 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 19261825 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 19261825 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 1103207 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12477995 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7701450 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 2634111 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2634111 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24690589 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28244897 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23721363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11583718 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29069370 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29069370 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 12527500 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12527500 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12527500 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 9703374 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 10702886 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 2009147 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2009147 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29027667 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 29027667 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 29027667 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29027667 — Biomarker: CD244 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD244; 2B4
Study 10636472 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 26520926 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26520926 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16891758 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16891758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30219823 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27630212 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 16843192 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16843192 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11164436 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 25154706 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19368899 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 19368899 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 16600924 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16600924 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 8725679 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15725943 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 15725943 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 29990690 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 27604335 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25439449 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23110676 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 22944145 — Biomarker: UBC mRNA
Type: Predictive Biomarker (PRD)
Genes: UBC
Study 16424843 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 12856386 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 10212170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31124147 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 28701288 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26664151 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29389692 — Biomarker: SUCO mRNA
Type: Predictive Biomarker (PRD)
Genes: SUCO; C1orf9; CH1; OPT; SLP1