AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT03372733 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00837148 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02906670 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02906670 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02906670 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study NCT02976857 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT03566030 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT02843048 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00470470 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study NCT00450593 — Biomarker: CDKN2A mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2A; CDKN2; MTS1
Study NCT04670328 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study NCT04670328 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT04371289 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04173507 — Biomarker: Serine/threonine-protein kinase STK11
Type: Safety Biomarker (SAF)
Genes: STK11
Study NCT04091516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04089579 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT01983579 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01983579 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT02586974 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02586974 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT02433132 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study NCT02433132 — Biomarker: Nasal potential difference
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03102606 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study NCT03102606 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study NCT04066452 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study NCT01522911 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study NCT03821233 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02500095 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT02465905 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study NCT02465905 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study NCT02465905 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT02152137 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study NCT00194441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01735461 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study NCT04517305 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02930499 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT00711087 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study NCT01334229 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT04881474 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04378972 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT04378972 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT04411147 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT00114140 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study NCT01368497 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT02816736 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study NCT03791112 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study NCT04429542 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00655993 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00926952 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study NCT02302417 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT00922441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02031861 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01518322 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study NCT04062669 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT00659711 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT00075816 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00075816 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT02845713 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03922321 — Biomarker: TSHR mRNA
Type: Predictive Biomarker (PRD)
Genes: TSHR; LGR3
Study NCT00155311 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study NCT02522689 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study NCT01511042 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study NCT01511042 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00396682 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT01472692 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03413540 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03214224 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT03509064 — Biomarker: 14-3-3 protein sigma
Type: Predictive Biomarker (PRD)
Genes: SFN; HME1
Study NCT03178149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04152135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04274933 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04274933 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study NCT04274933 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT04274933 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT04274933 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT01862978 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study NCT01862978 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03948763 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT01477346 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study NCT03726372 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT04256772 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study NCT03559972 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study NCT00529373 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT04201457 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study NCT02287181 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03268083 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT00247702 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study NCT00247702 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study NCT03857646 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT00087477 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT00162552 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00956501 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study NCT04444024 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04444024 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01530659 — Biomarker: CNTF mRNA
Type: Predictive Biomarker (PRD)
Genes: CNTF
Study NCT04057742 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study NCT00459563 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00118157 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00118157 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00118157 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03627975 — Biomarker: MMD mRNA
Type: Predictive Biomarker (PRD)
Genes: MMD; PAQR11
Study NCT01874353 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT01874353 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study NCT00372177 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04073537 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT04073537 — Biomarker: FGFR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study NCT01712620 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT01673295 — Biomarker: Complete renal response
Type: Surrogate Endpoint (SUR)
Study NCT02021981 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03307252 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study NCT03307252 — Biomarker: SLC22A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A2; OCT2
Study NCT04038905 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT04166786 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT03859167 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01692626 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03835923 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00455403 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00455403 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT00110396 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT00014430 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05669404 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03466450 — Biomarker: SHH mRNA
Type: Predictive Biomarker (PRD)
Genes: SHH
Study NCT02696343 — Biomarker: GLS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS2; GA
Study NCT03129724 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03684109 — Biomarker: 2-hydroxyglutarate
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00011648 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02389309 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT02389309 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study NCT01491763 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT04460911 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT04460911 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04460911 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT04460911 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT02570789 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00184886 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00184886 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study NCT03788850 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study NCT05570240 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT02641327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03103438 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT02471729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04298944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00968747 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study NCT00450879 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00450879 — Biomarker: VEGF
Type: Predictive Biomarker (PRD)
Genes: VEGFA; VEGF-A; VPF
Study NCT00450879 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT03903289 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01377948 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study NCT00688350 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03105180 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00494637 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT02687568 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01579773 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study NCT02277587 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03139474 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT00856492 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01938638 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01129557 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT03596957 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study NCT02242812 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01244438 — Biomarker: FGFR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT00151931 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01296776 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02504918 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02504918 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT03211676 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02847260 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT02847260 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study NCT01219816 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study NCT03383965 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study NCT02716961 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study NCT03631706 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03631706 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT03631706 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT02198170 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT03691701 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02942017 — Biomarker: SAGE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAGE1; SAGE
Study NCT00350207 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study NCT00350207 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT02772133 — Biomarker: PRCP mRNA
Type: Predictive Biomarker (PRD)
Genes: PRCP; PCP
Study NCT03473444 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study NCT02604342 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT02129231 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study NCT03981835 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study NCT01611727 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT02598635 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study NCT02598635 — Biomarker: Osteopontin
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SPP1; BNSP; OPN; PSEC0156
Study NCT02881398 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01723800 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study NCT04166838 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT01161069 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03312244 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00811733 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT06438614 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00273520 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT01904695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00518271 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT01139775 — Biomarker: CHEK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHEK1; CHK1
Study NCT00039559 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study NCT01622257 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study NCT02681861 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study NCT00155064 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT02352571 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04608487 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT03514524 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03514524 — Biomarker: SV2A mRNA
Type: Predictive Biomarker (PRD)
Genes: SV2A; KIAA0736; PSEC0174
Study NCT01071642 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT03926117 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04237376 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT04237376 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT06795841 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT06795841 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT06795841 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT06795841 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT02840474 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT02473627 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study NCT02473627 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study NCT02473627 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT02473627 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT00004495 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT03548818 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT01936844 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study NCT01936844 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03657875 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study NCT01486446 — Biomarker: DNA repair endonuclease XPF
Type: Predictive Biomarker (PRD)
Genes: ERCC4; ERCC11; XPF
Study NCT03023215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02869243 — Biomarker: BMP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: BMP4; BMP2B; DVR4
Study NCT04526028 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study NCT04526028 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT04526028 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL