AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 30150128 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27161894 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 27161894 — Biomarker: CYP27B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 27161894 — Biomarker: CYP24A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP24A1; CYP24
Study 27161894 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27161894 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27161894 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16042675 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 16042675 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 2124648 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 30039199 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 30039199 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 28616765 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23537332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25744115 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16856145 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21884013 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20580035 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 20580035 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 20580035 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20580035 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 16121967 — Biomarker: EDNRA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDNRA; ETA; ETRA
Study 11835038 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10999124 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3886566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27258230 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27258230 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27258230 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22240359 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 20650346 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20650346 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23159100 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 19178808 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25368541 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12605026 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 9147928 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 3975430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1388195 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1388195 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 4023620 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24762804 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 20174905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8828077 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11791032 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2205799 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2205799 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25616647 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 25616647 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 19299777 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14744921 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14744921 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11799264 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26167618 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29649996 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 29649996 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20139430 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20139430 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18672532 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14625133 — Biomarker: NPL mRNA
Type: Predictive Biomarker (PRD)
Genes: NPL; C1orf13
Study 11106203 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 11106203 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24251744 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22992267 — Biomarker: A1CF mRNA
Type: Predictive Biomarker (PRD)
Genes: A1CF; ACF; ASP
Study 16192735 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 16192735 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 16192735 — Biomarker: PLG mRNA
Type: Predictive Biomarker (PRD)
Genes: PLG
Study 16192735 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 3513670 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3513670 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31303349 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31303349 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1559334 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 29325289 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23490224 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9146850 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29212965 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27755389 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16368192 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 14600517 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30180236 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 27627073 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 22687788 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 20091113 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 20091113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17566094 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12192247 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 24322997 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17953808 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15359637 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 8123489 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 2678805 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1170119 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 28331291 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 24411753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18983947 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26104968 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 24714773 — Biomarker: MYL12A mRNA
Type: Predictive Biomarker (PRD)
Genes: MYL12A; MLCB; MRLC3; RLC
Study 10894871 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8507018 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3877474 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30301555 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30301555 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20136785 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20136785 — Biomarker: CCR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 1814866 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17605698 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15479314 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26369798 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26369798 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 26369798 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21328373 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 2184654 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2184654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26099241 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 18451385 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16921035 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 7919126 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 31790546 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 30287915 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 30287915 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30287915 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 30287915 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 18440674 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 18362295 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1425271 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24759827 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22531338 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22531338 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16136270 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7790471 — Biomarker: NSMAF mRNA
Type: Predictive Biomarker (PRD)
Genes: NSMAF; FAN
Study 30122341 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28248974 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24111288 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24111288 — Biomarker: ST8SIA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ST8SIA4; PST; PST1; SIAT8D
Study 24111288 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21327725 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21327725 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7969676 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 24710641 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 24710641 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 14634760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29464879 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29464879 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29464879 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22865548 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1851649 — Biomarker: FUT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FUT1; H; HSC
Study 31769619 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 9694068 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 25307511 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20826742 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20826742 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27856067 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26141466 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14510743 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 442223 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 22652468 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 12637609 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 12637609 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 18948412 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18075468 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 18075468 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 16441729 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6354933 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30779295 — Biomarker: FGR mRNA
Type: Predictive Biomarker (PRD)
Genes: FGR; SRC2
Study 21376385 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 14678901 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14678901 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 10148188 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16392280 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12356784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7787408 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 2338694 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31793171 — Biomarker: Arachidonate 5-lipoxygenase activating protein
Type: Safety Biomarker (SAF)
Genes: ALOX5AP; FLAP
Study 23324408 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11710407 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 11710407 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29629731 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 29629731 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 23975179 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30014565 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 28285617 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24051384 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 31375148 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 20630944 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8942407 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 24075527 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 21537491 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31652404 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 22844043 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6783519 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9819796 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30506451 — Biomarker: G0S2 mRNA
Type: Predictive Biomarker (PRD)
Genes: G0S2
Study 30506451 — Biomarker: ABHD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABHD5; NCIE2; CGI-58
Study 30506451 — Biomarker: PNPLA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PNPLA2; ATGL; FP17548
Study 26023905 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 26023905 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 8986487 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31425951 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 27619558 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 11800062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3340420 — Biomarker: TPI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPI1; TPI
Study 29650774 — Biomarker: CPA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA6; CPAH
Study 29650774 — Biomarker: PRPF31 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRPF31; PRP31
Study 29650774 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 27247177 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 11437473 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 7527100 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 4821036 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 23764639 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21940595 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11160635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3056073 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15660797 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16450017 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24107844 — Biomarker: LILRB4 mRNA
Type: Predictive Biomarker (PRD)
Genes: LILRB4; ILT3; LIR5
Study 24107844 — Biomarker: LILRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LILRB2; ILT4; LIR2; MIR10
Study 24107844 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24107844 — Biomarker: C-type lectin domain family 4 member C
Type: Pharmacodynamic Biomarker (PDY)
Genes: CLEC4C; BDCA2; CLECSF11; CLECSF7; DLEC; HECL; UNQ9361/PRO34150
Study 24107844 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 24107844 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 17336967 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17336967 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9853201 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21236483 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7554199 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28410510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16995587 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9292541 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 8038025 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12975635 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 8967706 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2983909 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31843269 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 16505196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25905441 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 6083688 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 30541098 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10655977 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 3884577 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 30153453 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30153453 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 15949725 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1