AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 25164513 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23325582 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23325582 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 23325582 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 23325582 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 23325582 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 23325582 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 23325582 — Biomarker: CTNNB1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CTNNB1; CTNNB; OK/SW-cl.35; PRO2286
Study 7666817 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15248853 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 15248853 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15635850 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 30895313 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 30895313 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 22216509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25787041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21699786 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 9356529 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8487564 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12900586 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12680882 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12680882 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8735864 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 25800756 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 29461600 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29461600 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27475262 — Biomarker: Urokinase plasminogen activator surface receptor
Type: Monitoring Biomarker (MOI)
Genes: PLAUR; MO3; UPAR
Study 24052631 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 6405773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25555562 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 25555562 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 21121927 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 31805134 — Biomarker: PCSK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK5; PC5; PC6
Study 20016796 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10221439 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7491855 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31409556 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 31409556 — Biomarker: CX3CL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CX3CL1; FKN; NTT; SCYD1; A-152E5.2
Study 31409556 — Biomarker: T-cell specific protein RANTES
Type: Safety Biomarker (SAF)
Genes: CCL5; D17S136E; SCYA5
Study 28698175 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16939514 — Biomarker: TRERF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRERF1; BCAR2; RAPA; TREP132
Study 16939514 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2161435 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2161435 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28442424 — Biomarker: TXN mRNA
Type: Predictive Biomarker (PRD)
Genes: TXN; TRDX; TRX; TRX1
Study 25655102 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 23551856 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12505865 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 12505865 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 12505865 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12505865 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 28936 — Biomarker: DBH mRNA
Type: Predictive Biomarker (PRD)
Genes: DBH
Study 15180757 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7640969 — Biomarker: FST mRNA
Type: Predictive Biomarker (PRD)
Genes: FST
Study 29747087 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 29747087 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 19635613 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8302148 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10361382 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 25150117 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19848199 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9424404 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 2972170 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 16871743 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 16871743 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 16871743 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26011507 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 23257347 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 23257347 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 15886245 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 15886245 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 10081536 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7593729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24104699 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 22449319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21094362 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21094362 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10907671 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 1418829 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1418829 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27207107 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 12623851 — Biomarker: CD52 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD52; CDW52; HE5
Study 12623851 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10599980 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30584292 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26960786 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19854729 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7117676 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31731368 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31731368 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 31731368 — Biomarker: Serum phosphate
Type: Surrogate Endpoint (SUR)
Study 31731368 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27490918 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 22813645 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21140357 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 21140357 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 21140357 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15501923 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11896120 — Biomarker: Dihydrothymine dehydrogenase
Type: Safety Biomarker (SAF)
Genes: DPYD
Study 8116715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30431499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12074253 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 19356621 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 19356621 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 17644511 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12358921 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 19770778 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17570265 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17570265 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17570265 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 382433 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 382433 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31335572 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 26192873 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30383458 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 21340377 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 18181252 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 18181252 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 11092517 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11092517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1957968 — Biomarker: FLNA mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FLNA; FLN; FLN1
Study 6274476 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25811674 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 9663476 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 9663476 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 9663476 — Biomarker: CDA
Type: Safety Biomarker (SAF)
Genes: CDD
Study 31188820 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 31188820 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31188820 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 16449030 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 4018467 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17637912 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10460529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30824825 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16733624 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16733624 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2872806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30458866 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 24377455 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24377455 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 22210566 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 22210566 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 22210566 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8949694 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 1827008 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31563697 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 25907781 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 25907781 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 6475754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6475754 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6475754 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25113081 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25113081 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 25113081 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 22190134 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21044831 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 16788927 — Biomarker: HGD mRNA
Type: Predictive Biomarker (PRD)
Genes: HGD; HGO
Study 12011968 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2666451 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27581812 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23278574 — Biomarker: DHFR
Type: Safety Biomarker (SAF)
Genes: DHFR1
Study 20016142 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 20016142 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 7889438 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19767074 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 3538945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30205371 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30205371 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24337154 — Biomarker: TLR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR3
Study 24337154 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 24337154 — Biomarker: TLR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR5; TIL3
Study 24337154 — Biomarker: MAP4K4 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP4K4; HGK; KIAA0687; NIK
Study 24337154 — Biomarker: MAP2K3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K3; MEK3; MKK3; PRKMK3; SKK2
Study 24337154 — Biomarker: CHUK mRNA
Type: Predictive Biomarker (PRD)
Genes: CHUK; IKKA; TCF16
Study 24337154 — Biomarker: CHUK
Type: Predictive Biomarker (PRD)
Genes: IKK1; IKK-alpha; IkBKA; NFKBIKA; IKKA
Study 24337154 — Biomarker: REL mRNA
Type: Predictive Biomarker (PRD)
Genes: REL
Study 24337154 — Biomarker: RELA mRNA
Type: Predictive Biomarker (PRD)
Genes: RELA; NFKB3
Study 11914161 — Biomarker: KCNIP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNIP3; CSEN; DREAM; KCHIP3
Study 19521070 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19521070 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11159234 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 8781301 — Biomarker: HGD mRNA
Type: Predictive Biomarker (PRD)
Genes: HGD; HGO
Study 1352496 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6496393 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6496393 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31601569 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31601569 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19491556 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 9428829 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8512094 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18698246 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 15713351 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9524014 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27503233 — Biomarker: FUT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FUT2; SEC2
Study 23620429 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 21679357 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 1377306 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1377306 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23018440 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23018440 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12564742 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11200748 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11200748 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25463450 — Biomarker: PHLDA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PHLDA2; BWR1C; HLDA2; IPL; TSSC3
Study 21232664 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 19235536 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 1020902 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31630117 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27469171 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 11746863 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11746863 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 23525499 — Biomarker: ALDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH2; ALDM
Study 18239561 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18239561 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8819106 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 8819106 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8819106 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 16793562 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16793562 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7472905 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 26255764 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9778719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7709944 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16464386 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16464386 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30236136 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 20042092 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16036076 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11451272 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 21407247 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 21407247 — Biomarker: Apolipoprotein A-IV
Type: Monitoring Biomarker (MOI)
Genes: APOA4
Study 17925087 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 30589600 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28322071 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28322071 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 14693409 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18068888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14693167 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 14693167 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 29351736 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17986525 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26