AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 21477901 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16779731 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12032393 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 25494974 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 22616628 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 15262456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15262456 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1631876 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 6431795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31968059 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 10707752 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10707752 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23070803 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 14606076 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14606076 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 14606076 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 14606076 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 14606076 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 14606076 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30666153 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 30666153 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30666153 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30928925 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26468074 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17507345 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17507345 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11229465 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 11229465 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 11229465 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 11229465 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 11229465 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 7908257 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29910837 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21628653 — Biomarker: TMPRSS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMPRSS13; MSP; TMPRSS11
Study 16969059 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 11867823 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11867823 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30541586 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 19346662 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19346662 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30926369 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 30926369 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 26870788 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 19262457 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15272899 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 9242341 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9242341 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 9242341 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8494702 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 15983288 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15983288 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 15983288 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11999911 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 11999911 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 11999911 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 11999911 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 10372975 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 10372975 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 25728846 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 25728846 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29073815 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 18756037 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11731729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9256187 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9256187 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 28129251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25585949 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 25585949 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 21350054 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11463545 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 9663723 — Biomarker: PLXNA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 27032074 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18672254 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30791079 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15367192 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 31839158 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 29329305 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31596518 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 31596518 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 23576043 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 19514093 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 15456623 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9237962 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27225988 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27225988 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 25256892 — Biomarker: HSPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPB1; HSP27; HSP28
Study 25256892 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25256892 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 10028374 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30143879 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23113934 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 1586375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26354383 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 20543706 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12527967 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22780937 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 20547990 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 12860863 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 28721992 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 21423021 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 21423021 — Biomarker: CYP4F2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP4F2
Study 21423021 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 17038251 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12355570 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 6159865 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 25981758 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 19375250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11584084 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 11584084 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 7886652 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7886652 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2190927 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12831591 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 9921711 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 8677862 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1984373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29291739 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24674234 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 20530518 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 16169400 — Biomarker: L-acetylcarnitine
Type: Safety Biomarker (SAF)
Study 12501022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1715478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29073347 — Biomarker: TNFSF13 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 22160637 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 22160637 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22160637 — Biomarker: TOP2A mRNA
Type: Predictive Biomarker (PRD)
Genes: TOP2A; TOP2
Study 15781339 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 12148881 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 12148881 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12148881 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 10589004 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 27981528 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 576887 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 31277784 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 30946207 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30946207 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27651331 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 27651331 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9230275 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18174609 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18174609 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 29940166 — Biomarker: CHM mRNA
Type: Predictive Biomarker (PRD)
Genes: CHM; REP1; TCD
Study 29940166 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 15730542 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 12538173 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 1623657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19307271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17595032 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 17595032 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17595032 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 10855738 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 10855738 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1288925 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 22839514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15983321 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 15983321 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 29927860 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 25005893 — Biomarker: GMCL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GMCL2; GCL; GMCL1L; GMCL1P1
Study 25005893 — Biomarker: PHLDA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PHLDA2; BWR1C; HLDA2; IPL; TSSC3
Study 19387899 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19387899 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17151807 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study 14674932 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9020283 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20510974 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 20510974 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12436219 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7699968 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2566284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27988297 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 23711530 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 17165022 — Biomarker: MMP12 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP12; HME
Study 9527417 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 30486682 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30486682 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17052779 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11552016 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 9722293 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10707032 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10707032 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9018517 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 20926006 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 16096169 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 8792730 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8792730 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 8792730 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 8792730 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1637513 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1637513 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29672821 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 27109860 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 27109860 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30541645 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 30541645 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28199143 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 28199143 — Biomarker: DHDDS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHDDS; HDS
Study 17228991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9004051 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 29618772 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19556519 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9139621 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1848567 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 18030515 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25150183 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25150183 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25150183 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 25150183 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 22097972 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 19638620 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 17941284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9622279 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 7841755 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 7841755 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9032182 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 28675520 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 26371168 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26371168 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25495720 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25495720 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25495720 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17555561 — Biomarker: TFF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TFF1; BCEI; PS2
Study 17555561 — Biomarker: CCND1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND1; BCL1; PRAD1
Study 17555561 — Biomarker: PDZK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PDZK1; CAP70; NHERF3; PDZD1
Study 17555561 — Biomarker: AGR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AGR2; AG2; UNQ515/PRO1030
Study 17555561 — Biomarker: LUM mRNA
Type: Predictive Biomarker (PRD)
Genes: LUM; LDC; SLRR2D
Study 17555561 — Biomarker: DCN mRNA
Type: Predictive Biomarker (PRD)
Genes: DCN; SLRR1B
Study 17555561 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17555561 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15223728 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15223728 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 15223728 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15223728 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22057896 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 22057896 — Biomarker: SOD2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SOD2
Study 16790625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15609652 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9600792 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31735362 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 16352794 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 17501760 — Biomarker: EIF2AK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EIF2AK2; PKR; PRKR
Study 31565242 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31565242 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1