AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 17406886 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7641661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26712187 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26712187 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24024499 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 24024499 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24024499 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24024499 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11846843 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 7138753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31268130 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 31268130 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 24420556 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 17312209 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 15353025 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3221375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17001471 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 9122013 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9122013 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 6615664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6615664 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 16950948 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 11374008 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25621429 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 20195575 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 26564024 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 24995191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17013567 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17013567 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17013567 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 15823826 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 10064759 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2318517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2318517 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 20162528 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20162528 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20162528 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 20162528 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 18219179 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18219179 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11391125 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 9886725 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26025798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22157768 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 31583921 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25773009 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 7798544 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 30424796 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 24723220 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 20842069 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12589712 — Biomarker: IGF2R mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF2R; MPRI
Study 1683249 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10364784 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24133059 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22493101 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 19070025 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 16335907 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 11995344 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 9701620 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1898841 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27492324 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27492324 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27492324 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27492324 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 19171951 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17224709 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 2059591 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26806917 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 19647623 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study 19647623 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 19647623 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17721395 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17721395 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31826360 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31826360 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 31323516 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 25193390 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study 23470209 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16837920 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 10951511 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29853660 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29853660 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 29853660 — Biomarker: FLT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT4; VEGFR3
Study 29853660 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 29853660 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 29853660 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27193748 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24525316 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20399945 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1773423 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 31675175 — Biomarker: PSD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSD4; EFA6B; TIC
Study 11996608 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11996608 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23958252 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 23958252 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23958252 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23958252 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17284629 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17284629 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17284629 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3311648 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25545821 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16816481 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11035314 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1454160 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 11135227 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 11135227 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11135227 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 11135227 — Biomarker: FasL mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: FASLG; APT1LG1; CD95L; FASL; TNFSF6
Study 20087377 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10381910 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study 29676592 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29676592 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29676592 — Biomarker: CXCR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR3; GPR9
Study 28573748 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 18046594 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18046594 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 8614301 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8614301 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23565815 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23565815 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23565815 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15201559 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3270664 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 27004411 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 27004411 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 23528159 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18584876 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 11821454 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study 29023829 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 16925285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8605592 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22849580 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22849580 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20417879 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18683667 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 15911947 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10574596 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 10574596 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 10574596 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 10574596 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 10574596 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12837046 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12837046 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24457472 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 24457472 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 17090635 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17090635 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9736816 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9736816 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28963124 — Biomarker: SLC7A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC7A5; CD98LC; LAT1; MPE16
Study 28963124 — Biomarker: SLC36A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC36A1; PAT1
Study 28963124 — Biomarker: SLC38A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC38A2; ATA2; KIAA1382; SAT2; SNAT2
Study 22664478 — Biomarker: LDHA mRNA
Type: Predictive Biomarker (PRD)
Genes: LDHA; PIG19
Study 22664478 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22664478 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 22664478 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 22664478 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22664478 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22664478 — Biomarker: Hypoxia-inducible factor 1-alpha
Type: Predictive Biomarker (PRD)
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 19337169 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3020692 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 11752037 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 7487504 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 30621764 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17899047 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30936633 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2882082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31464558 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 21394895 — Biomarker: HRG mRNA
Type: Predictive Biomarker (PRD)
Genes: HRG
Study 10356669 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 2696505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31912605 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 25664779 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23771193 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 22384546 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11729034 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2203486 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30975923 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 30975923 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 30975923 — Biomarker: HRG mRNA
Type: Predictive Biomarker (PRD)
Genes: HRG
Study 28118028 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17277040 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17277040 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10423639 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3297467 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3297467 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18467730 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 8620278 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8620278 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30115263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17548728 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17548728 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17548728 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11246058 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11246058 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 11246058 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 23333095 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 23333095 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 20687956 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18771406 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 18771406 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15048595 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10728943 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8807096 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 1381611 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 1381611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6208185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31271885 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27798510 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19528902 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17505157 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 17505157 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24838894 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24838894 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20649614 — Biomarker: PHEX mRNA
Type: Predictive Biomarker (PRD)
Genes: PHEX; PEX
Study 9927366 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6781156 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31583977 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 29480916 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 23168372 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23168372 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 23168372 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1623908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27869358 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23434617 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23434617 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 23434617 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23434617 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16970087 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7956632 — Biomarker: HLA-DQB1
Type: Safety Biomarker (SAF)
Genes: IDDM1; CELIAC1
Study 30805607 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19390517 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19390517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19390517 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15282264 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 15282264 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 15282264 — Biomarker: CYP3A7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A7
Study 22108915 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 22108915 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3