AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 9860036 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8589159 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 31510721 — Biomarker: PCSK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK5; PC5; PC6
Study 25890480 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 19414675 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19414675 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 29793869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28295143 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26252749 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 23718900 — Biomarker: FGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF2; FGFB
Study 23718900 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 22575988 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16541481 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28455318 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 24321183 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 24321183 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24321183 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24321183 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2459543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15784645 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27053195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9241285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26763851 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12574563 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21084403 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21084403 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 17289894 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 14563654 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24216034 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17694391 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 15774238 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9801994 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31938726 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31938726 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 30037817 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30037817 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 19942995 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14722206 — Biomarker: ITGAM mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGAM; CD11B; CR3A
Study 14722206 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 14722206 — Biomarker: LTB mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB; TNFC; TNFSF3
Study 21106086 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29703335 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 29703335 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 22229650 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20550223 — Biomarker: TOX mRNA
Type: Predictive Biomarker (PRD)
Genes: TOX; KIAA0808
Study 20550223 — Biomarker: REL mRNA
Type: Predictive Biomarker (PRD)
Genes: REL
Study 20234301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20234301 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19029270 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 19029270 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 12207568 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12207568 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8670315 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8670315 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 6135076 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22130425 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 17646413 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 17646413 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 12409716 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 7633141 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 3720570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19931756 — Biomarker: HYLS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HYLS1; HLS
Study 30773798 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30773798 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 30773798 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 30773798 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 30773798 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26833624 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 29567399 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 22781309 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16542392 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16542392 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 16542392 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 11910595 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1783919 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 25545238 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15048065 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 9149578 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 31697272 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31697272 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25937633 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23513399 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15523294 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 22184381 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22184381 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 17967221 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2373136 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 2373136 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 29460712 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 29460712 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 23883377 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 19650752 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 11368732 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 27715368 — Biomarker: RIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RIT1; RIBB; RIT; ROC1
Study 21123186 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 30609411 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 24123098 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22958580 — Biomarker: LSR mRNA
Type: Predictive Biomarker (PRD)
Genes: LSR; ILDR3; LISCH
Study 16307219 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16307219 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 16307219 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19390752 — Biomarker: TNFR1B
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 11446724 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28183047 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 28183047 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 28183047 — Biomarker: Cyclin-dependent kinase inhibitor 1
Type: Safety Biomarker (SAF)
Genes: CDKN1A
Study 28183047 — Biomarker: CTNNB1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CTNNB1; CTNNB; OK/SW-cl.35; PRO2286
Study 28183047 — Biomarker: CASP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CASP3; CPP32
Study 28183047 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 28183047 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 12065339 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7648772 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 7648772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30355322 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 22205311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15795448 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31171876 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28794054 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28794054 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28794054 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23514874 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 21199979 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 16004778 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16004778 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16004778 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2681508 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2681508 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28410617 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24069844 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 19699861 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 27199121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25701829 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 18193385 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17106142 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12612168 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1600852 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1600852 — Biomarker: Serum hemoglobin A1C
Type: Surrogate Endpoint (SUR)
Study 1600852 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22456954 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22456954 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15823640 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15823640 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10381769 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9345413 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28853210 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28853210 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17330681 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28648618 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16372588 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12225725 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10436103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7573844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31117236 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 26545369 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 26545369 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 21140269 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17016059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30321318 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26023212 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17897270 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17897270 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11912385 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 2128988 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 2128988 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 29235560 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29235560 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29235560 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 21029013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28379325 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15249716 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 7813219 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 7813219 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study 6319152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14763918 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14763918 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14763918 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 11346729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28821519 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 31161692 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19828561 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 15716196 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29378197 — Biomarker: TLR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR7; UNQ248/PRO285
Study 24153001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16707980 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 25151339 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 28600466 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 15159322 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 15159322 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 9726695 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9726695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22978318 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 19041041 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 8858671 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 17431604 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 22826271 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22826271 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29972759 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 29972759 — Biomarker: AXL mRNA
Type: Predictive Biomarker (PRD)
Genes: AXL; UFO
Study 29972759 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24382782 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 21993078 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9708644 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9708644 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 7893440 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30540337 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 30540337 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26923543 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 26061330 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 18789762 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18789762 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15231443 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15641767 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 363334 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 363334 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 20032538 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 21365405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18440341 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 8960574 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 1413942 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 27887597 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 9388311 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 9388311 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 31099300 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31099300 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31099300 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 27077879 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27077879 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27077879 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24622117 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 24622117 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24622117 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22914404 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 16001233 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA