AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 11821829 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30168613 — Biomarker: HOXA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HOXA1; HOX1F
Study 30168613 — Biomarker: EMX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EMX1
Study 30168613 — Biomarker: ECE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ECE1
Study 30168613 — Biomarker: PFKP mRNA
Type: Predictive Biomarker (PRD)
Genes: PFKP; PFKF
Study 30168613 — Biomarker: CLEC11A mRNA
Type: Predictive Biomarker (PRD)
Genes: CLEC11A; CLECSF3; LSLCL; SCGF
Study 30168613 — Biomarker: B3GALT6 mRNA
Type: Predictive Biomarker (PRD)
Genes: B3GALT6
Study 30168613 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 29849178 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 20582464 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 18048574 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18048574 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7757309 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1554276 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 31987248 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 12924540 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12924540 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 10607690 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18581184 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 11836010 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 8573621 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 21756523 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8163252 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8163252 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11579696 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2687336 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2687336 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31580707 — Biomarker: PCSK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK5; PC5; PC6
Study 19357529 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8573809 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 23489186 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 7854076 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1826454 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26471194 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9639376 — Biomarker: DDR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 9639376 — Biomarker: EDNRA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDNRA; ETA; ETRA
Study 9639376 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9639376 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 9639376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30969032 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 21527360 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 21527360 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 10759711 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 27974398 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 11283429 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11283429 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9431285 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8507125 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8507125 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20097702 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 20097702 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20097702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16162940 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 1804644 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27721230 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27721230 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27721230 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25509696 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18847425 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8255415 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23549522 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 21631324 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12477759 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10951534 — Biomarker: UCP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP2; SLC25A8
Study 10951534 — Biomarker: UCP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP3; SLC25A9
Study 8858463 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8858463 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 27357182 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 27357182 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22628490 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 12165396 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 7671361 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 7671361 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28476271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30715250 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28715532 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 28715532 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 1691287 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20739720 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 15941534 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30690866 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23104564 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 23104564 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 12505939 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19567163 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 19567163 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 1980660 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27935886 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27935886 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 27935886 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27935886 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 107908 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 107908 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 29735881 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20678684 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 2137653 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27283929 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 3289737 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 28478985 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 28478985 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 20601412 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 10234582 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23910226 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 21989186 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 1683559 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 1683559 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31475296 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19919396 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16890574 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 16890574 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 11742191 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 31037611 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 21691610 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17585313 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 24297940 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 10550151 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 7598070 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31266529 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 23585744 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23585744 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11176729 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11176729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29698447 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 29698447 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23719550 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 23719550 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17457338 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1653594 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24170718 — Biomarker: PICALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PICALM; CALM
Study 20961784 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17326029 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 16303295 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 11218985 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1315646 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 1315646 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22607938 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 25483480 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 24858755 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 2320558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19716960 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12231521 — Biomarker: KLRK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRK1; D12S2489E; NKG2D
Study 12231521 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 26350766 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 22860014 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22860014 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19010583 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 11290882 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 11290882 — Biomarker: DDC mRNA
Type: Predictive Biomarker (PRD)
Genes: DDC; AADC
Study 11290882 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28753863 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28869786 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 27278276 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24342775 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22321963 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21194249 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 21194249 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12682621 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10726921 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10726921 — Biomarker: Insulin receptor substrate 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IRS1
Study 8934373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8934373 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22072154 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10687258 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8701872 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9289524 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 9289524 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 9289524 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24504100 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24504100 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24504100 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 22854323 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22854323 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 20071999 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 17922014 — Biomarker: HMMR mRNA
Type: Predictive Biomarker (PRD)
Genes: HMMR; IHABP; RHAMM
Study 17922014 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 11953279 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 31511080 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 22539172 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17121868 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15060873 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15060873 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15060873 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28242866 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 12915429 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12915429 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21896540 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 21896540 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 19399887 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19399887 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12456429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1674835 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6110504 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27555505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23868103 — Biomarker: SHC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SHC1; SHC; SHCA
Study 11570641 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 8163319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29748315 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 30561744 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 25037012 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19155993 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15744902 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11991217 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11991217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7539853 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25404569 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19383732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11351770 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15296889 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25348274 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19786240 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 16684823 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 9236262 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 8237098 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3092363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21455255 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 24944393 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24944393 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3125973 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 3125973 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 3125973 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 30597771 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 28202779 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28202779 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28202779 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23036940 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21625929 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 21625929 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17022864 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17022864 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17022864 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1395118 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21194910 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21194910 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21194910 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20003299 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14605513 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27487914 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27487914 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27487914 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27487914 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22072741 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20487050 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29722251 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 19703948 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 10496523 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 10496523 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 30760421 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16296699 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31154425 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 30010353 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18318169 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28418213 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 25486090 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 21595743 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17242700 — Biomarker: Retinoblastoma-associated protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: RB1
Study 9456071 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)