AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 9553912 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7934767 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7934767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12437706 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26584195 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 24657803 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17143187 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7977146 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24513589 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20795385 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20795385 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 10028858 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 19826270 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19826270 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 19826270 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25509057 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25509057 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22166848 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19384953 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 19384953 — Biomarker: TYRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TYRP1; CAS2; TYRP; TYRRP
Study 19384953 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 19384953 — Biomarker: SLC24A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC24A5; JSX; NCKX5
Study 19384953 — Biomarker: SLC45A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC45A2; AIM1; MATP
Study 19384953 — Biomarker: POMC mRNA
Type: Predictive Biomarker (PRD)
Genes: POMC
Study 19384953 — Biomarker: ATRN mRNA
Type: Predictive Biomarker (PRD)
Genes: ATRN; KIAA0548; MGCA
Study 19384953 — Biomarker: MC1R mRNA
Type: Predictive Biomarker (PRD)
Genes: MC1R; MSHR
Study 9067498 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 28065453 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26239594 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27107066 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25060946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7729938 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 7729938 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 7027894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9151051 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 30527153 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26252788 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 26252788 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 25047139 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 15657372 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15657372 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15657372 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15657372 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 10789879 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3831144 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30661944 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 30661944 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30661944 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 30661944 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25151225 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20131030 — Biomarker: Vitamin K-dependent protein C
Type: Safety Biomarker (SAF)
Genes: PROC
Study 23264241 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23264241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18159027 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9797910 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9797910 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8586825 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8586825 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29262813 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29262813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23636255 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 19615907 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 28571996 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22064591 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 18636266 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 18636266 — Biomarker: CA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA4
Study 16959828 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31130722 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 31130722 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 26618455 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 30655182 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14760157 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11313304 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 11313304 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31873772 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21981454 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 21981454 — Biomarker: TRPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPA1; ANKTM1
Study 21981454 — Biomarker: MUC5B mRNA
Type: Predictive Biomarker (PRD)
Genes: MUC5B; MUC5
Study 21981454 — Biomarker: MUC5AC mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MUC5AC; MUC5
Study 21981454 — Biomarker: TRPM8 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPM8; LTRPC6; TRPP8
Study 8276050 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8276050 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21334854 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 17130431 — Biomarker: CCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR1; CMKBR1; CMKR1; SCYAR1
Study 18031294 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 12115321 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 10336919 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10336919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30789780 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 22613136 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11642510 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7882780 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 23314694 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20498403 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 14620390 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1465034 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 1465034 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29907581 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26465829 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11982742 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 3024869 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30858203 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 24648103 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 18555464 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 7586952 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31646414 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15569128 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15569128 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8154425 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 30153859 — Biomarker: Urokinase plasminogen activator surface receptor
Type: Monitoring Biomarker (MOI)
Genes: PLAUR; MO3; UPAR
Study 25220898 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23194489 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 23194489 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20162301 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20162301 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 7033946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19394503 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10775552 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3919803 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18569935 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8475869 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8475869 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30318515 — Biomarker: TGFBR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TGFBR1; ALK5; SKR4
Study 30318515 — Biomarker: Macrophage inflammatory protein 1-alpha
Type: Monitoring Biomarker (MOI)
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 30318515 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 21684626 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 15883316 — Biomarker: Amyloid beta peptide (1-40)
Type: Pharmacodynamic Biomarker (PDY)
Genes: APP; A4; AD1
Study 15883316 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 10734323 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28640770 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28640770 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 11163733 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8104270 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3943286 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24358145 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 31161196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23526069 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23526069 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23526069 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23526069 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9093237 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21925260 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21925260 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 2649308 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30923873 — Biomarker: BMAL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BMAL1; ARNTL; BHLHE5; MOP3; PASD3
Study 30923873 — Biomarker: PER2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PER2; KIAA0347
Study 30923873 — Biomarker: CRY1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CRY1; PHLL1
Study 30923873 — Biomarker: NR1D1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1D1; EAR1; HREV; THRAL
Study 28873749 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25936724 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23730991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15010556 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23298524 — Biomarker: ALOX5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALOX5; LOG5
Study 12558462 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28228428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9105569 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2294135 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2294135 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2294135 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9822508 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 535777 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 22434736 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22434736 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9620508 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22699287 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16115125 — Biomarker: ID1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ID1; BHLHB24; ID
Study 16115125 — Biomarker: FGFR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR3; JTK4
Study 16115125 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study 28622623 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 28622623 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 28622623 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21894446 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 19581537 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 17121785 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11996957 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11996957 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9583841 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7684524 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 2879832 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 22096040 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30565412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2179284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23789288 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 30148969 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27401638 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12700955 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29327055 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25265658 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 17167111 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22773302 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20127139 — Biomarker: MAP2K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K1; MEK1; PRKMK1
Study 8187320 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 8187320 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8187320 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 31969368 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 23500314 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16412796 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 29351490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12145076 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18513639 — Biomarker: ADORA2A
Type: Safety Biomarker (SAF)
Genes: RDC8
Study 12521654 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 12521654 — Biomarker: SERPINA7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA7; TBG
Study 12521654 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study 8733685 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24748637 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 11005561 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11005561 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 30202185 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 10579613 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 8729530 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 24289920 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 22344966 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22344966 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22344966 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 15970067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15970067 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15970067 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31803504 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31803504 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 24195949 — Biomarker: SH2D1A mRNA
Type: Predictive Biomarker (PRD)
Genes: SH2D1A; DSHP; SAP
Study 8095119 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 2876741 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24898426 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18690349 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15978306 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15978306 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15978306 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15978306 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10500023 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 22809163 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 22276821 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22276821 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 22276821 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 20858863 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20858863 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15848695 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10206381 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10206381 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10206381 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 10206381 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 30457436 — Biomarker: HDC mRNA
Type: Predictive Biomarker (PRD)
Genes: HDC