AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 20533764 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15867181 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8877074 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22446296 — Biomarker: FasL mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: FASLG; APT1LG1; CD95L; FASL; TNFSF6
Study 8601931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2004539 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23134084 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 18311687 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 18311687 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 18311687 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 1629381 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29385952 — Biomarker: ANKS4B mRNA
Type: Predictive Biomarker (PRD)
Genes: ANKS4B; HARP
Study 23911756 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23911756 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7480568 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30732732 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 23883736 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21911633 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1687852 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6366805 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6366805 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 29745095 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 29745095 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 29795283 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 1854361 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6717701 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 30281882 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20090550 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 2239569 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31039812 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15043515 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30901502 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 29141784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27342765 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 27342765 — Biomarker: MTRR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTRR
Study 27342765 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 21212155 — Biomarker: RAF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAF1; RAF
Study 21212155 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 21212155 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8181617 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 15926058 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15926058 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15926058 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 15926058 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 18953882 — Biomarker: CDH3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDH3; CDHP
Study 12939228 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19591010 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15463836 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 25913479 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17538878 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15031350 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 15031350 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21452293 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21452293 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16606972 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 9087387 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9087387 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 9087387 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 9087387 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 26811534 — Biomarker: CELF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CELF4; BRUNOL4
Study 26811534 — Biomarker: Cardiac troponin T
Type: Safety Biomarker (SAF)
Genes: TNNT2
Study 16124442 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12204875 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 12572374 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 12572374 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25870084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24473536 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 21885724 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 21885724 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15194332 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15194332 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9158829 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8480985 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2434787 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12357041 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7636936 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11854763 — Biomarker: REST mRNA
Type: Predictive Biomarker (PRD)
Genes: REST; NRSF; XBR
Study 9645184 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 3064775 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31451364 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 26123256 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19267255 — Biomarker: STAR mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAR; STARD1
Study 15493172 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 7930702 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7930702 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25716649 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20602089 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18845497 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 18845497 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 30661474 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27270263 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22270321 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 11543743 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 24113040 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 24113040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17870051 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 8776813 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 22647517 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22647517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22647517 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20621734 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20621734 — Biomarker: TNFSF10 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF10; APO2L; TRAIL
Study 11528582 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8169385 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 28623969 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28623969 — Biomarker: FGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF2; FGFB
Study 28623969 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 28623969 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28623969 — Biomarker: VEGFB mRNA
Type: Predictive Biomarker (PRD)
Genes: VEGFB; VRF
Study 28623969 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 11070146 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11070146 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23433403 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 23433403 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21875858 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15007086 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 12469051 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 9846593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23652274 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 21283158 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 18957534 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11982466 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 9619011 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 9619011 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9619011 — Biomarker: Succinate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: SDHD
Study 2502974 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 776351 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21666744 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 19927363 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 19927363 — Biomarker: ERCC8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC8; CKN1; CSA
Study 8077353 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31977000 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 21067382 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 15956965 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 10432325 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24922198 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12568207 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12568207 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12568207 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29777144 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 18814836 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study 12732586 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10821360 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29447770 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 26817879 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17651416 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 16329022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11917284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31880586 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 29231317 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 22942402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21485668 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15202297 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11552906 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 9559415 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7513981 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 17952589 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17952589 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 30759235 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30759235 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30759235 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20047560 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20047560 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23078984 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10453833 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 10453833 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 7788682 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7788682 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23422155 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23422155 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9717065 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27469583 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23798345 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 12445223 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 1696669 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31442599 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31442599 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15308069 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11217907 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 11217907 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 11069569 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 22621795 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20554983 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18612042 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29172992 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22695488 — Biomarker: CPD mRNA
Type: Predictive Biomarker (PRD)
Genes: CPD
Study 27381507 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 19078903 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25426808 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28244291 — Biomarker: CR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR2; C3DR
Study 24659208 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 725 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 31238370 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 21835288 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21835288 — Biomarker: Heart fatty acid-binding protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FABP3; FABP11; MDGI
Study 21835288 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19747247 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 16675905 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16675905 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16675905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8491393 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8491393 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 30350153 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25380167 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25380167 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 22082432 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 18450322 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 11833826 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11833826 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25205361 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study 20658483 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29453769 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 21116186 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17167159 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12585099 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10612483 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 10612483 — Biomarker: PLTP mRNA
Type: Predictive Biomarker (PRD)
Genes: PLTP
Study 10612483 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 10612483 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 7742423 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20880870 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 3312501 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30982743 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30982743 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 30982743 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25402418 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 25029619 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19478337 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 19478337 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17225918 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 9715861 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 28154006 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23784379 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 20017916 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20017916 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12488406 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21412846 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 19365587 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24956323 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29275880 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16990190 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24389433 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 19702079 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 25637294 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 8857071 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8857071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1387609 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)