AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 30862817 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22434095 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 17660173 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23751727 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19934290 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 19934290 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19934290 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 14724047 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 31648986 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 21318637 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15556053 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9105945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22908326 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18639771 — Biomarker: NPC1L1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NPC1L1
Study 18639771 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6817123 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21821813 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 21821813 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 16279283 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12390056 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6180050 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31730466 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 31730466 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 29362205 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25011661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17515403 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12619921 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25979833 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 25979833 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 25979833 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 23359491 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 2450234 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31338868 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23456732 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9589229 — Biomarker: PGR mRNA
Type: Predictive Biomarker (PRD)
Genes: PGR; NR3C3
Study 19433387 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 19433387 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19433387 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16772708 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22405251 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16291411 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31059697 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 23818121 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 16495695 — Biomarker: PLAT mRNA
Type: Predictive Biomarker (PRD)
Genes: PLAT
Study 12795812 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8248660 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8248660 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22090363 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22090363 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 22090363 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 22090363 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12379550 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 7181738 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7181738 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25847554 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25847554 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25847554 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23545664 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23545664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24721903 — Biomarker: STAT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT4
Study 24721903 — Biomarker: STAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT1
Study 12488953 — Biomarker: HLA-DQB1
Type: Safety Biomarker (SAF)
Genes: IDDM1; CELIAC1
Study 25956750 — Biomarker: MLH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MLH1; COCA2
Study 25956750 — Biomarker: DNA mismatch repair protein MSH2
Type: Predictive Biomarker (PRD)
Genes: MSH2
Study 25956750 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 17804473 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17804473 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 11950430 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11950430 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 10226398 — Biomarker: CPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPZ
Study 27055521 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 18474451 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9843762 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 28008145 — Biomarker: DNA mismatch repair protein MSH2
Type: Predictive Biomarker (PRD)
Genes: MSH2
Study 28008145 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 19708000 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 19708000 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22117083 — Biomarker: MOBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MOBP
Study 22117083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20420104 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16444435 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8252957 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30615231 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29573224 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 27480654 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22093109 — Biomarker: DEFA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DEFA1; DEF1; DEFA2; MRS; DEFA1B
Study 20407630 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17879544 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12142119 — Biomarker: KCNH2
Type: Safety Biomarker (SAF)
Genes: Kv11.1; HERG; erg1
Study 10442116 — Biomarker: FST mRNA
Type: Predictive Biomarker (PRD)
Genes: FST
Study 375433 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19541014 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11252073 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 9333879 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3551506 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 25387876 — Biomarker: SFR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SFR1; C10orf78; MEI5; MEIR5
Study 21681167 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 21681167 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 7877117 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 7877117 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 7877117 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 7877117 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29583066 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29583066 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21667009 — Biomarker: INPP5J mRNA
Type: Predictive Biomarker (PRD)
Genes: INPP5J; PIB5PA; PIPP
Study 15585987 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 15585987 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29637820 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 31502637 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 29571976 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 27994066 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 24285428 — Biomarker: MGP mRNA
Type: Predictive Biomarker (PRD)
Genes: MGP; MGLAP; GIG36
Study 12518180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12518180 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29091570 — Biomarker: Survival motor neuron protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 24853043 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 15097240 — Biomarker: RAPGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 15097240 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9286892 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9286892 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23139614 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 19465554 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 19465554 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19465554 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 2192018 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30003521 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19142106 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 17381399 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15133405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31089282 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study 2664522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18460483 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12754275 — Biomarker: PLTP mRNA
Type: Predictive Biomarker (PRD)
Genes: PLTP
Study 12754275 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 12754275 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 19065891 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10235449 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 396086 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19737321 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11500333 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 11500333 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 28444964 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12728160 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10810433 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 6506819 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30126775 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29587159 — Biomarker: MEST mRNA
Type: Predictive Biomarker (PRD)
Genes: MEST; PEG1
Study 29579327 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 28213365 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28213365 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 26453484 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26909888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20688033 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 17506001 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11721446 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 2301243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7436639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10652956 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 10652956 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9330124 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1534042 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16284466 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 12882907 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 1806186 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22047909 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 15705728 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 23832605 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 17030655 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9734743 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2538676 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31977371 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 21653735 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 21653735 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 19361304 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16997737 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9191528 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 18212288 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 11303311 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11303311 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11303311 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31688451 — Biomarker: PDE10A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE10A
Study 27271613 — Biomarker: miR-18a
Type: Safety Biomarker (SAF)
Genes: MIR18A
Study 17415555 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12669751 — Biomarker: OSM mRNA
Type: Predictive Biomarker (PRD)
Genes: OSM
Study 25566730 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24722500 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 7664433 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16317106 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11384023 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28005247 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26227087 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26227087 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26227087 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26227087 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 19657998 — Biomarker: ERCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC2; XPD; XPDC
Study 9610957 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 9610957 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 7527105 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21485024 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16818663 — Biomarker: CD58 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD58; LFA3
Study 16818663 — Biomarker: FCER1A mRNA
Type: Predictive Biomarker (PRD)
Genes: FCER1A; FCE1A
Study 16818663 — Biomarker: NFATC4 mRNA
Type: Predictive Biomarker (PRD)
Genes: NFATC4; NFAT3
Study 16818663 — Biomarker: NFRKB mRNA
Type: Predictive Biomarker (PRD)
Genes: NFRKB; INO80G
Study 16818663 — Biomarker: Inhibin beta B chain
Type: Safety Biomarker (SAF)
Genes: INHBB
Study 16818663 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14521653 — Biomarker: KCNQ1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNQ1; KCNA8; KCNA9; KVLQT1
Study 6380856 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24716713 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22933567 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 30624373 — Biomarker: PLB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLB1; PLB
Study 30624373 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23403474 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8359644 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 30866027 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29678193 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 24956865 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 8604657 — Biomarker: HGD mRNA
Type: Predictive Biomarker (PRD)
Genes: HGD; HGO
Study 26906014 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18455211 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 11022053 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31537812 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 31537812 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27739230 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 21764706 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 21764706 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 18385744 — Biomarker: Mitochondrial membrane potential
Type: Pharmacodynamic Biomarker (PDY)
Study 18385744 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8762212 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8762212 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8762212 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 8762212 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22321325 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 15598475 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 21278424 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 21278424 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9130032 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19023429 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 2876745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)