AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 19438927 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15649723 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 12424509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10090633 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 10090633 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10090633 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 7032828 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9208337 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9208337 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3794134 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14505773 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8466682 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8466682 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 1776803 — Biomarker: Protein AMBP
Type: Safety Biomarker (SAF)
Genes: AMBP; HCP; ITIL
Study 1776803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6132524 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28267790 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24387157 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25386736 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25386736 — Biomarker: Mitochondrial membrane potential
Type: Pharmacodynamic Biomarker (PDY)
Study 25386736 — Biomarker: CASP9
Type: Predictive Biomarker (PRD)
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 17371783 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15726550 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 12238905 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12238905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28682837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25504576 — Biomarker: SIRT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIRT3; SIR2L3
Study 25504576 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 22848080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9987698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7351286 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31152080 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31152080 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31152080 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28591543 — Biomarker: TLR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR7; UNQ248/PRO285
Study 15291499 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15291499 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11414349 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 11414349 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 15277374 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15277374 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8215672 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 29897544 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 22493913 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31711229 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 31261732 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 29036790 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29036790 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 29036790 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22938928 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19445546 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 17855758 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 11336083 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11336083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9660431 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9660431 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9660431 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15254883 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2490828 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1649840 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30262155 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 27495137 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19845991 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 15701187 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8314427 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26545320 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 1709239 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 20044312 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16014046 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19561014 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 17555006 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15811355 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23410714 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23410714 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14759591 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 14759591 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 14759591 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 14759591 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 2408425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27379625 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8584384 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 7682927 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 19289931 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19289931 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 30256215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22410389 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20307903 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 20307903 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 22349543 — Biomarker: LHB mRNA
Type: Predictive Biomarker (PRD)
Genes: LHB
Study 8925521 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8925521 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8925521 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 19510 — Biomarker: CPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPZ
Study 25001274 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21734423 — Biomarker: SH2D1A mRNA
Type: Predictive Biomarker (PRD)
Genes: SH2D1A; DSHP; SAP
Study 8653995 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 8653995 — Biomarker: CYP2C19
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: P450IIC19; CPCJ
Study 22325086 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9552059 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 15390234 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 1097143 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 28407660 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 15248139 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15248139 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24803523 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24803523 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 23474997 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 15374554 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9431832 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 3545744 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26886716 — Biomarker: Serum hemoglobin A1C
Type: Surrogate Endpoint (SUR)
Study 18457248 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18457248 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 18457248 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12229307 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 7915989 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19392579 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10602349 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8621850 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 29524000 — Biomarker: SLC2A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A2; GLUT2
Study 29441909 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24081158 — Biomarker: COL1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL1A1
Study 24081158 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 31799993 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 25248345 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25248345 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 21883001 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9791144 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9791144 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27099247 — Biomarker: C1QL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 22516692 — Biomarker: MCTS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCTS1; MCT1
Study 20444742 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8973709 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1282179 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20536366 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2994386 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15883262 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9607039 — Biomarker: CTBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CTBS; CTB
Study 7649608 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 23483198 — Biomarker: DRD3
Type: Safety Biomarker (SAF)
Study 21993434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16563397 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 3886023 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 12374512 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30499618 — Biomarker: DNA mismatch repair protein MSH2
Type: Predictive Biomarker (PRD)
Genes: MSH2
Study 30499618 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 21779819 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15826746 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8199810 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8199810 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31874497 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 31874497 — Biomarker: UGT2B7 mRNA
Type: Predictive Biomarker (PRD)
Genes: UGT2B7; UGTB2B9
Study 31874497 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 31874497 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 31874497 — Biomarker: OPRD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OPRD1; OPRD
Study 31874497 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 31874497 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 31874497 — Biomarker: P2RY12 mRNA
Type: Predictive Biomarker (PRD)
Genes: P2RY12; HORK3
Study 16115337 — Biomarker: IPP mRNA
Type: Predictive Biomarker (PRD)
Genes: IPP; KLHL27
Study 16115337 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16115337 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 3896455 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9279722 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 27351217 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 25189213 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23775961 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 31736187 — Biomarker: TNFRSF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1A; TNFAR; TNFR1
Study 31736187 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31736187 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31736187 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 27221874 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 24262967 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 24262967 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 24262967 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 7897158 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 7897158 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7897158 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15316750 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 11172188 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19543808 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 28207554 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 17086503 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 15483784 — Biomarker: LTB mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB; TNFC; TNFSF3
Study 7888537 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31200019 — Biomarker: CPD mRNA
Type: Predictive Biomarker (PRD)
Genes: CPD
Study 8275621 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 28681988 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 18795912 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26152773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8908222 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20195266 — Biomarker: PRKAR2B mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKAR2B
Study 20195266 — Biomarker: ADGRV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADGRV1; GPR98; KIAA0686; KIAA1943; MASS1; VLGR1
Study 20195266 — Biomarker: FMNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMNL3; FHOD3; FRL2; KIAA2014; WBP3
Study 20195266 — Biomarker: RNF144A mRNA
Type: Predictive Biomarker (PRD)
Genes: RNF144A; KIAA0161; RNF144; UBCE7IP4
Study 20195266 — Biomarker: ASTN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASTN2; KIAA0634
Study 20195266 — Biomarker: SOX5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOX5
Study 20195266 — Biomarker: ATF7IP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATF7IP2; MCAF2
Study 11223322 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24983748 — Biomarker: CIDEA mRNA
Type: Predictive Biomarker (PRD)
Genes: CIDEA
Study 22644026 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 22644026 — Biomarker: UGT2B7 mRNA
Type: Predictive Biomarker (PRD)
Genes: UGT2B7; UGTB2B9
Study 20394040 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20394040 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 20394040 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9546928 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2931840 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29808753 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 23017527 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19781896 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9414432 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 2065926 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 27677865 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 27677865 — Biomarker: C-C motif chemokine 4
Type: Monitoring Biomarker (MOI)
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 25122497 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 17907106 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29788293 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 24598584 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12597674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10334425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1721246 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30650480 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19852290 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 11589262 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28045625 — Biomarker: Proliferation marker protein Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67
Study 28045625 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 19539184 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15327558 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 28273855 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27411760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21884017 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11738688 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 8296748 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3046309 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29136037 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 21167685 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21167685 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19183414 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 9754723 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 31826326 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 31826326 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 31826326 — Biomarker: MMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP2; CLG4A
Study 31826326 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 30611722 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25563737 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 25563737 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 25563737 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 25563737 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)