AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT00895479 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT01288300 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01288300 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00831220 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03086694 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00824785 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00824785 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT04969562 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03625258 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study NCT03625258 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT03562182 — Biomarker: LPCAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LPCAT1; AYTL2; PFAAP3
Study NCT02722798 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT02621190 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study NCT01663662 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT05311072 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study NCT02349672 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study NCT01189656 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT03259165 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00736190 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT03065751 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study NCT01694758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04200833 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04391829 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT00844974 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT00844974 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT00903292 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00991796 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study NCT01852799 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study NCT01852799 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00258687 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00558402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00072111 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study NCT03669731 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02236000 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01891032 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study NCT04224584 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study NCT04224584 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study NCT02230267 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT02230267 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT00166634 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02011828 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT00845130 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT01041547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00950300 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03917758 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study NCT03917758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00365053 — Biomarker: Histone acetylation
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00112437 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03513211 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT03878550 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study NCT04604938 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study NCT01510405 — Biomarker: PLK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLK1; PLK
Study NCT01510405 — Biomarker: Aurora kinase A
Type: Predictive Biomarker (PRD)
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT00942916 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT02873975 — Biomarker: CHEK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHEK1; CHK1
Study NCT02873975 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT02873975 — Biomarker: CCNE1 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCNE1; CCNE
Study NCT00794664 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04198935 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04198935 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04198935 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01372930 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02167594 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03986463 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study NCT01215383 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study NCT01215383 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study NCT01215383 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02271035 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT02118324 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01947738 — Biomarker: Cathepsin S
Type: Pharmacodynamic Biomarker (PDY)
Genes: CTSS
Study NCT00107263 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03567551 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study NCT01939990 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00327587 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00001469 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study NCT00001469 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study NCT00109057 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00155649 — Biomarker: NOTCH4 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOTCH4; INT3
Study NCT00155649 — Biomarker: DISC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DISC1; KIAA0457
Study NCT00155649 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00155649 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study NCT00595348 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT00688844 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00688844 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study NCT00185120 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT00185120 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01834027 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03516565 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study NCT03786705 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02229084 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02229084 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT01224561 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study NCT04172480 — Biomarker: MPHOSPH8 mRNA
Type: Predictive Biomarker (PRD)
Genes: MPHOSPH8; MPP8
Study NCT04797936 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT00001763 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study NCT00001763 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT04322513 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01204138 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00685854 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00685854 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT00772408 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study NCT00059423 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00059423 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT02004769 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00901719 — Biomarker: APLNR mRNA
Type: Predictive Biomarker (PRD)
Genes: APLNR; AGTRL1; APJ
Study NCT01283763 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study NCT01192087 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01192087 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00746928 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00948480 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01507662 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03922750 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT03922750 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT02344849 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT01216020 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01019356 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT01951209 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study NCT00580190 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study NCT00580190 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT06516172 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01116791 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study NCT01116791 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01607970 — Biomarker: OXTR mRNA
Type: Predictive Biomarker (PRD)
Genes: OXTR
Study NCT00433745 — Biomarker: WT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WT1
Study NCT00812630 — Biomarker: MENT mRNA
Type: Predictive Biomarker (PRD)
Genes: MENT; C1orf56; UNQ547/PRO1104
Study NCT00812630 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04612309 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04612309 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT04612309 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study NCT01625403 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study NCT02414282 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01622764 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01622764 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT01167023 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01271647 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01312506 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT04163094 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT01828112 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT01827280 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT01243151 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study NCT01243151 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04054258 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02994836 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03021876 — Biomarker: SIRT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIRT3; SIR2L3
Study NCT01378962 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01378962 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT01736839 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT01736839 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study NCT00421863 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03317080 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study NCT04013763 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT03093363 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study NCT00646984 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00646984 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT04348422 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT00884819 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT02364258 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study NCT01887795 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01749085 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT00162929 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT04228484 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT00165152 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT00165152 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study NCT04731324 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT04731324 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study NCT03699150 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01719549 — Biomarker: FGFR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT01719549 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02169440 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study NCT00540358 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00540358 — Biomarker: Gamma-Histone H2AX
Type: Pharmacodynamic Biomarker (PDY)
Genes: H2AX; H2AFX
Study NCT00540358 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT02364869 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study NCT02364869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00385736 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02818751 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study NCT02337322 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04345822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02123823 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT02123823 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01282086 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01924286 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00236002 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT04152356 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study NCT01650857 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study NCT01317147 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study NCT00157521 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT02528019 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT02528019 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT00432952 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02046122 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study NCT00397657 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04314661 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT00579358 — Biomarker: TBX5 mRNA
Type: Predictive Biomarker (PRD)
Genes: TBX5
Study NCT00579358 — Biomarker: GATA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GATA4
Study NCT02093728 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT02093728 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT03985657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04402892 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00525330 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT03396354 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01965327 — Biomarker: Mitochondrial frataxin
Type: Monitoring Biomarker (MOI)
Genes: FXN; FRDA; X25
Study NCT01965327 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT00990574 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03174158 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study NCT00785603 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study NCT01720953 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT01720953 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT05909605 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04606888 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT04606888 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study NCT05021276 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study NCT00521508 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00664196 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00481169 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01781117 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study NCT02336633 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study NCT03425461 — Biomarker: SEMA4D mRNA
Type: Predictive Biomarker (PRD)
Genes: SEMA4D; C9orf164; CD100; SEMAJ
Study NCT00834353 — Biomarker: CYP2E1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2E1; CYP2E
Study NCT01165060 — Biomarker: ABCD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCD1; ALD
Study NCT05049200 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT00668395 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study NCT04459754 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT03637127 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT00860262 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02417571 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01806272 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01806272 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT02810223 — Biomarker: CARTPT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CARTPT; CART
Study NCT04007835 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1