AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 12832683 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12832683 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31218545 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27075909 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 22080632 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 22080632 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19535971 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12566894 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2363546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16410202 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8998092 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22447003 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22447003 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 22447003 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22447003 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 22447003 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 22447003 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12865611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2423800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24420549 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20872550 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17189550 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17189550 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10756219 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 27578134 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 23013806 — Biomarker: STAC mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAC; STAC1
Study 21964962 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 18569272 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 8559480 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26188541 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26188541 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17196810 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 17196810 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 15201546 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15201546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29845723 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 21529363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6639916 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28272464 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 3330988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24002086 — Biomarker: IL11 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL11
Study 24002086 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study 31235374 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 23076450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17086096 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 17086096 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1977708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31472039 — Biomarker: DPP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DPP3
Study 29600897 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28721700 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8686047 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1828764 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28235510 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17612359 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 7362504 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10208787 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7104154 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20041911 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 11874817 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10232362 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 31444972 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 31444972 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 31444972 — Biomarker: AXL mRNA
Type: Predictive Biomarker (PRD)
Genes: AXL; UFO
Study 31444972 — Biomarker: CCL18 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 31444972 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28958110 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8651549 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 6514178 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24915052 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22168345 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28370973 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28370973 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28370973 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23552127 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27311415 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 16448252 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 29712745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29712745 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24144761 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17522607 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17522607 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 17522607 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 29423715 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24558403 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 18410863 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30431398 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 20648661 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18931099 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 27730665 — Biomarker: FPR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FPR2; FPRH1; FPRL1; LXA4R
Study 22963235 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18339002 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18339002 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10862229 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 8180726 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8180726 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18366445 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8641115 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8641115 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 8641115 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24729586 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 24729586 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 24729586 — Biomarker: UGT2B7 mRNA
Type: Predictive Biomarker (PRD)
Genes: UGT2B7; UGTB2B9
Study 18476416 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 14600850 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29534465 — Biomarker: Bacteroidetes phylum
Type: Safety Biomarker (SAF)
Study 31984623 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 25233647 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19935427 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19935427 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19935427 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19935427 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 16883914 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8828744 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3933861 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 30385613 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30385613 — Biomarker: FLT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT4; VEGFR3
Study 28028723 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28028723 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28028723 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 21742306 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study 19919714 — Biomarker: ID1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ID1; BHLHB24; ID
Study 9416888 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3114203 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 24005959 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24005959 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24005959 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19131132 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 18199394 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18199394 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 18199394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16893641 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 11293237 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11293237 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1735313 — Biomarker: TAOK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 28891198 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28891198 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22490629 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 19436934 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 17697904 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 15716194 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 8613305 — Biomarker: DPT mRNA
Type: Predictive Biomarker (PRD)
Genes: DPT
Study 17296530 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 17296530 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31178155 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28215362 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28215362 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21624226 — Biomarker: AZIN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AZIN2; ADC; KIAA1945; ODCP
Study 9298736 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31005204 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 28656542 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28656542 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 28656542 — Biomarker: WAP four-disulfide core domain protein 2
Type: Predictive Biomarker (PRD)
Genes: WFDC2; HE4; WAP5
Study 12636463 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 10666187 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29215189 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22424722 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31384902 — Biomarker: FGG mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGG; PRO2061
Study 10541047 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10541047 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 10541047 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10541047 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 6433770 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26545199 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 26545199 — Biomarker: SLPI mRNA
Type: Predictive Biomarker (PRD)
Genes: SLPI; WAP4; WFDC4
Study 26845098 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 26845098 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26845098 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25418907 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16960445 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11476119 — Biomarker: CARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARS1; CARS
Study 26284153 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 17146380 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23660686 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23660686 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8068604 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8068604 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16331115 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6237116 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 6237116 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 29522979 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29522979 — Biomarker: CYP27B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 29522979 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 27305512 — Biomarker: CYBC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYBC1; C17orf62; EROS
Study 2242520 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16713391 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16713391 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16713391 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15295409 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27711918 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27711918 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18175748 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 18175748 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17015053 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 12031821 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12031821 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 24753036 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 17339868 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 17339868 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23648946 — Biomarker: EDNRA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDNRA; ETA; ETRA
Study 23648946 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 15356664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8304366 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10658376 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 10658376 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10658376 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2128866 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 2128866 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28161147 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8044919 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8044919 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29705451 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29705451 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 29705451 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26037429 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26037429 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15299060 — Biomarker: PCLO mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLO; ACZ; KIAA0559
Study 8308936 — Biomarker: PRCP mRNA
Type: Predictive Biomarker (PRD)
Genes: PRCP; PCP
Study 22947269 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12463319 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 12463319 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 7026255 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30664267 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30664267 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31446143 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 8004358 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 2682593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23303873 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23303873 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15078238 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 9271009 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 28459069 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 10717781 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 7075652 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21449990 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)