AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 12542598 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8808110 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1361175 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1361175 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31170994 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 31170994 — Biomarker: TRPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPA1; ANKTM1
Study 19297314 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 8466068 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 21424698 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17572323 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 17572323 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12951862 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19324974 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19324974 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10214011 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31782032 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25985446 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study 31577070 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 23146788 — Biomarker: DMRT1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DMRT1; DMT1
Study 17918321 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12018633 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 23739686 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23739686 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14989442 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 11228294 — Biomarker: Neurofilament light polypeptide
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: NEFL; NF68; NFL
Study 2468049 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29271486 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study 26888806 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 26888806 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23963331 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 18326136 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11712430 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 11712430 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11712430 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 30168626 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 27194023 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11341495 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11341495 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11341495 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11341495 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 412995 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27958765 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 22498181 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6996793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22463614 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11984215 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11984215 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23384300 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 20938439 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 20938439 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20938439 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16595221 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 12883329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9273524 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6518665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23150144 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21496415 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11516093 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8381931 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 28949012 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 24129358 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23878319 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study 20034487 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14757967 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 11990103 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11990103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29753693 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 18725648 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 18725648 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15953803 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 28033302 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24885942 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24885942 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 12091047 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8594118 — Biomarker: DPT mRNA
Type: Predictive Biomarker (PRD)
Genes: DPT
Study 20586601 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20586601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18236139 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 18236139 — Biomarker: ABCG2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 31227014 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 28948979 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28948979 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24378958 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 24378958 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7109988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27460638 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27460638 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17981885 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 8729588 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8729588 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25582578 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17242633 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14739793 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 335912 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24841333 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11093505 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22257576 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 31190476 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28968759 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18986859 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 11694687 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9134635 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 9134635 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25612882 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15666380 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8948268 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 1766495 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 30928279 — Biomarker: FOXO3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXO3; FKHRL1; FOXO3A
Study 30928279 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25935101 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25935101 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18201582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11115423 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9450174 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 9450174 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24285128 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 24285128 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24285128 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 14596355 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9065092 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31127500 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 31127500 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31127500 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31127500 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 31127500 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17197840 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9727072 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7953225 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28638000 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28638000 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22127691 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22127691 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9291301 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 29667496 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27043671 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 27043671 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 27043671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15819388 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15819388 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24008055 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21549352 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 21792642 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19278902 — Biomarker: Major prion protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRNP; ALTPRP; PRIP; PRP
Study 9690055 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30973970 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study 21940785 — Biomarker: Dihydrothymine dehydrogenase
Type: Safety Biomarker (SAF)
Genes: DPYD
Study 17324239 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 23591294 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 23591294 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23591294 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 10229291 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6293712 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31409394 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 22989819 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20589313 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 20589313 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study 28004415 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28004415 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25607117 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21901395 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21901395 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 2439782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24944041 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 20122630 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9106787 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30230266 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 30230266 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23147875 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9700674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31714323 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31714323 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25540268 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 16573800 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 2387667 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 2387667 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 28751226 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 25199059 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 19526589 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 19526589 — Biomarker: Hypoxia-inducible factor 1-alpha
Type: Predictive Biomarker (PRD)
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 16493377 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 31574087 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31574087 — Biomarker: Chitinase-3-like protein 1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: CHI3L1
Study 31574087 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 16478794 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 16478794 — Biomarker: PGP mRNA
Type: Predictive Biomarker (PRD)
Genes: PGP
Study 29066876 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25138579 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 9370179 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2877131 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 25100892 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22888676 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19250082 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 2270581 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 28249614 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22275471 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 22275471 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 22275471 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22275471 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11477461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9700713 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2913770 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2913770 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2913770 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26307616 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 346292 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23358230 — Biomarker: USH1G mRNA
Type: Predictive Biomarker (PRD)
Genes: USH1G; SANS
Study 30840130 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29235300 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29235300 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 9620358 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 9620358 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 23596780 — Biomarker: CGN mRNA
Type: Predictive Biomarker (PRD)
Genes: CGN; KIAA1319
Study 7945477 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29723220 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 26216383 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26216383 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22218118 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21137665 — Biomarker: UROD mRNA
Type: Predictive Biomarker (PRD)
Genes: UROD
Study 21137665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2698748 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 30866056 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 12151429 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 16083511 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 25460033 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21600005 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16685052 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 15273083 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11763409 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30150651 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20680689 — Biomarker: CAMP mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMP; CAP18; FALL39; HSD26
Study 17889580 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 17277852 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1355099 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 29907153 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 26979631 — Biomarker: PRKCA mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKCA; PKCA; PRKACA
Study 26979631 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 26979631 — Biomarker: MMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP2; CLG4A
Study 26979631 — Biomarker: TIMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TIMP2
Study 26979631 — Biomarker: IL16 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL16
Study 26979631 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 26979631 — Biomarker: LIFR mRNA
Type: Predictive Biomarker (PRD)
Genes: LIFR