AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23046709 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23046709 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19578221 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9706371 — Biomarker: KCNH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNH2; ERG; ERG1; HERG
Study 1396833 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31029863 — Biomarker: SMAD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMAD4; DPC4; MADH4
Study 31029863 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31029863 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 19777735 — Biomarker: MT2A mRNA
Type: Predictive Biomarker (PRD)
Genes: MT2A; CES1; MT2
Study 18082489 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18082489 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18082489 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18082489 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 6993250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25381560 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28244718 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 28244718 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 19071184 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 15866414 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15866414 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 25751673 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 20347467 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 18554238 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 21794296 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10971602 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 10971602 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 29187046 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24786196 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15819670 — Biomarker: Major prion protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRNP; ALTPRP; PRIP; PRP
Study 31747948 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29787831 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 17557985 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17557985 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2649822 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 18698222 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14743888 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9711448 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2677374 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21309005 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21309005 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19950087 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15618271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2694923 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31564841 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31564841 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27040455 — Biomarker: CD47 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD47; MER6
Study 23497636 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 9210530 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9210530 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9210530 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23237107 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17178701 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17178701 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17178701 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7691269 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 7691269 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 3531038 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3531038 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26872105 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24924486 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 9430799 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9430799 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30558006 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25042870 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 25042870 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 25042870 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 25042870 — Biomarker: AGTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study 25042870 — Biomarker: SLC38A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 25042870 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 22180560 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8927736 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 2055140 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 28292320 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26721135 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17923654 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11981075 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31487383 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 19024003 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9324103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9324103 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31902327 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24096631 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12661776 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12661776 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30929823 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30929823 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30929823 — Biomarker: VEGFD mRNA
Type: Predictive Biomarker (PRD)
Genes: VEGFD; FIGF
Study 27841945 — Biomarker: NPC1L1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NPC1L1
Study 27841945 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study 26002728 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26002728 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23246855 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 19846544 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 16895071 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11854119 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11854119 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11854119 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 3046231 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3046231 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31121022 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 31121022 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23704713 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 7507765 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2906887 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29632101 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 15459598 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 27650174 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 25503550 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23775875 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 20400651 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 1380588 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 1380588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30949987 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18070803 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 11920396 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 25872641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22366046 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17504357 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8275623 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23172934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27131611 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 9054757 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 21166851 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21166851 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21166851 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 10766581 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1848392 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12048432 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2265168 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29020983 — Biomarker: CXCR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR2; IL8RB
Study 22348338 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 22348338 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 22348338 — Biomarker: TLR2
Type: Predictive Biomarker (PRD)
Genes: TIL4; CD282
Study 2083170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31988276 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 16713737 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23510102 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 26692555 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 23771530 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 17276955 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 3908127 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 26257796 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21554520 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17542944 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 9516059 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17646493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15735200 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 26686567 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20350942 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 16227990 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9456253 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7610506 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 779590 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19920048 — Biomarker: ADORA2A
Type: Safety Biomarker (SAF)
Genes: RDC8
Study 19920048 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19920048 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16954734 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22708640 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22708640 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22708640 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22708640 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 2261152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26921460 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 25568553 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22233204 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 22233204 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 22233204 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 22233204 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 22233204 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 22233204 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 9927022 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7779149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9747868 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2893877 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 29212368 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9220319 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 25268778 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18809731 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 28778281 — Biomarker: Histone acetylation
Type: Pharmacodynamic Biomarker (PDY)
Study 22428491 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 19416257 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 9885179 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 8279943 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8279943 — Biomarker: Interleukin 1 alpha
Type: Safety Biomarker (SAF)
Genes: IL1A; IL1F1
Study 8279943 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8279943 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18407467 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 24265159 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24265159 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 11149478 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30987432 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29696915 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17571481 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6923655 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31852846 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30423846 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30423846 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24997559 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 29846719 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 29846719 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 25667293 — Biomarker: UBC mRNA
Type: Predictive Biomarker (PRD)
Genes: UBC
Study 17515729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15570253 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15570253 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 30140707 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 22318706 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 22318706 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8501156 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 29604160 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29604160 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23691171 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 19366101 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19366101 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9935227 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7925516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 336453 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25743173 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 24613523 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 15226466 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 15226466 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16203934 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 10090538 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10090538 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26201184 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 14984379 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9135734 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 9135734 — Biomarker: Nasal potential difference
Type: Pharmacodynamic Biomarker (PDY)
Study 8198341 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25693004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11840286 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 11840286 — Biomarker: Nqo1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: NQO1; DIA4; NMOR1
Study 11840286 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 7083512 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16433927 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14583064 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6377491 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 24913351 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 24913351 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24913351 — Biomarker: Histone acetylation
Type: Pharmacodynamic Biomarker (PDY)
Study 9988284 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30461337 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20204674 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 9019175 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26764413 — Biomarker: HCN4 mRNA
Type: Predictive Biomarker (PRD)
Genes: HCN4
Study 26764413 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)