AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 11426093 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7589598 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 2141109 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 18045306 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1719655 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 1719655 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30561237 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30561237 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 25554997 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19705345 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 8783673 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25591469 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 25591469 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22650125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19651919 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19651919 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16840742 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12756385 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12756385 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31924632 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31924632 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9628521 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7511753 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7511753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9110123 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30178240 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27529625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11641292 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11641292 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7978396 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2692407 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22027717 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 19059524 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15371986 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 15371986 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 7991070 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 7991070 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 2663151 — Biomarker: MIA mRNA
Type: Predictive Biomarker (PRD)
Genes: MIA
Study 15752392 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19807887 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19807887 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 19807887 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9822268 — Biomarker: CCL11 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL11; SCYA11
Study 21654270 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 19344008 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24382690 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 8644660 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11739447 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 7684118 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 3320786 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28566070 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28566070 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15315724 — Biomarker: SLC4A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC4A2; AE2; EPB3L1; HKB3; MPB3L
Study 11167103 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 9266276 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8281717 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 29803589 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12577416 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 25463092 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22515587 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 18614926 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18614926 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 18614926 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 18614926 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18614926 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 18614926 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 18614926 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30126153 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 30126153 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26003334 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16402229 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 8122716 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 28974567 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28974567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23972966 — Biomarker: CTBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CTBS; CTB
Study 23972966 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 23972966 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 16508577 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25683060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9280322 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27072903 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 27072903 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 22639289 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22639289 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22639289 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 8171949 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25146070 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16050413 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22289106 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 7594124 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26493588 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 23800161 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 25222607 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 23176879 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18456678 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 18456678 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18456678 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14871033 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8922358 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15235348 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31305011 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 7840317 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 21648282 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 21648282 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 19422580 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 9447569 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 8162662 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8162662 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 3258200 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31856812 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 25418186 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21567262 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21567262 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11208407 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19016938 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19016938 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21245238 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 21245238 — Biomarker: SP9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP9
Study 21138531 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 8972009 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8972009 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 24877590 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24877590 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 24877590 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 11780380 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 17605895 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17605895 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7541210 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 7541210 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30192390 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 20490798 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 20490798 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 20490798 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 14646349 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 14646349 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 14646349 — Biomarker: STAT5A mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT5A; STAT5
Study 14646349 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 14646349 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 14646349 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 2809562 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 2809562 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 22385133 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 20664016 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20664016 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20664016 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20664016 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12439805 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10353554 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10353554 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19208305 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16534680 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 12492458 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 12492458 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 12462824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8856491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23418046 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23418046 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23418046 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21335930 — Biomarker: GAL3ST1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAL3ST1; CST
Study 11721319 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11721319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3033593 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 12942586 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8846275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29211305 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25281438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18157288 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 10208507 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10208507 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 10208507 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 10208507 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 10208507 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 10208507 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17869497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16849999 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 16849999 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24125402 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 24125402 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24947459 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 14513417 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28232097 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 28232097 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 23966331 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 18157013 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10930199 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22068809 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2883920 — Biomarker: BLVRA mRNA
Type: Predictive Biomarker (PRD)
Genes: BLVRA; BLVR; BVR
Study 8690806 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 8690806 — Biomarker: PDXP mRNA
Type: Predictive Biomarker (PRD)
Genes: PDXP; CIN; PLP; PLPP
Study 8690806 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 23857741 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23857741 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16510370 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1897688 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20390477 — Biomarker: NRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRP1; NRP; VEGF165R
Study 17440005 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 23278132 — Biomarker: EDAR mRNA
Type: Predictive Biomarker (PRD)
Genes: EDAR; DL
Study 19100416 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 1618253 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 9558432 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28673814 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 28673814 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21346689 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12079900 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28488685 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11554015 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 11554015 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 11554015 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8148280 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23748750 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 19099634 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24687830 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 24687830 — Biomarker: HLA-DQA1
Type: Safety Biomarker (SAF)
Genes: CELIAC1
Study 20399512 — Biomarker: IFNGR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNGR1
Study 20399512 — Biomarker: CD209 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD209; CLEC4L
Study 20399512 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 20399512 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 20399512 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 20399512 — Biomarker: Interleukin 12 beta
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL12B; NKSF2
Study 20399512 — Biomarker: IL12RB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL12RB1; IL12R; IL12RB
Study 20399512 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 20399512 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 7949271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2853751 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31339533 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 15930210 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29901815 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29901815 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29901815 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1