AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 393518 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24115827 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 21887230 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 21887230 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26386578 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 20738314 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18204233 — Biomarker: CFL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CFL1; CFL
Study 16681888 — Biomarker: MYOC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYOC; GLC1A; TIGR
Study 16681888 — Biomarker: OPTN mRNA
Type: Predictive Biomarker (PRD)
Genes: OPTN; FIP2; GLC1E; HIP7; HYPL; NRP
Study 15605213 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21364138 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 24662398 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 24662398 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23381198 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10647760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2057034 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30152428 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30152428 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 24863570 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 24863570 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 24863570 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 24863570 — Biomarker: COL1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL1A1
Study 12418063 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 11956045 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 11956045 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 761334 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31634108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19948277 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 19948277 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 9234827 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26589105 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 20160653 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 18515689 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 1728527 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18501061 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18501061 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30358156 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 18418962 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10325897 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20798339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18586814 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 16320349 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 7081096 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31405875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26700109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26700109 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11870165 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 3476058 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 1919423 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26273146 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26273146 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24589724 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 17971946 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 17971946 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11447080 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11447080 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11447080 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15470487 — Biomarker: KLRD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRD1; CD94
Study 11467911 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 7976460 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 19244691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9291702 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29779815 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 29779815 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29779815 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22687580 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 31959263 — Biomarker: DHCR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: DHCR7; D7SR
Study 31959263 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 31959263 — Biomarker: CYP2R1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2R1
Study 31959263 — Biomarker: CYP24A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP24A1; CYP24
Study 31959263 — Biomarker: CYP27B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 31959263 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 30777024 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 15306152 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 9421239 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20444845 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11359431 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 9217273 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9217273 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 9217273 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 3325090 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25365012 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25365012 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8635377 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 29036427 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8615705 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8615705 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30985644 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25887103 — Biomarker: SLC25A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A3; PHC; OK/SW-cl.48
Study 30612858 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 8678065 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8678065 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8678065 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 8678065 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 8591624 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 2760254 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29188863 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 26004026 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15258329 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 10691900 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 30975047 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 29427355 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 29427355 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 26536214 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8909433 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10075382 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2139303 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26823793 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22884505 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22884505 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 1336998 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 29140227 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 25660493 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 15476476 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28237861 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14740601 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 14740601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9307742 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 29114972 — Biomarker: RARA mRNA
Type: Predictive Biomarker (PRD)
Genes: RARA; NR1B1
Study 15776267 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 12012627 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30449071 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 25697379 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 10941601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10941601 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1588260 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study 25093998 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 18683819 — Biomarker: PDXP mRNA
Type: Predictive Biomarker (PRD)
Genes: PDXP; CIN; PLP; PLPP
Study 16179660 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 28636405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25394762 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28937313 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28937313 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17474951 — Biomarker: ARX mRNA
Type: Predictive Biomarker (PRD)
Genes: ARX
Study 11463009 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 11463009 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 20443014 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30503849 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30503849 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21057704 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 11052464 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11052464 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 11052464 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 6386484 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21806683 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 2644129 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 301745 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 301745 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 23742144 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23742144 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 30110693 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30110693 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30110693 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7620695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2490833 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2490833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31652226 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 18346185 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27220601 — Biomarker: COL1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL1A1
Study 27220601 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 27220601 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 27220601 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 22650145 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20606481 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15683483 — Biomarker: WBP2NL mRNA
Type: Predictive Biomarker (PRD)
Genes: WBP2NL; PAWP
Study 10421921 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28786523 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 28786523 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 2972597 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28628969 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24824900 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 12828103 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12828103 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9206238 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 3579494 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 20679559 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20679559 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20679559 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20679559 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21776461 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21776461 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3129318 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 31476881 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12011136 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 10210974 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25239030 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 31730832 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 30762744 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 28940638 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17198101 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 31043522 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 27683405 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27683405 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 27683405 — Biomarker: CXCL1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 27683405 — Biomarker: C-X-C motif chemokine 5
Type: Safety Biomarker (SAF)
Genes: CXCL5; ENA78; SCYB5
Study 21360353 — Biomarker: USH1G mRNA
Type: Predictive Biomarker (PRD)
Genes: USH1G; SANS
Study 15025744 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 7523785 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30728951 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 26464453 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 26464453 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12200242 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27778256 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 19281922 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19281922 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17407516 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 15184247 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 9605372 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7013560 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19674695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15960063 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 7735265 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31088511 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 11774111 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11774111 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20528005 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 29523095 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 7194733 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 30252571 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 30252571 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 9918565 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 8589013 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8589013 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 343678 — Biomarker: HBE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HBE1; HBE
Study 28392272 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28392272 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 28392272 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23826104 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 21419704 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 19641312 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 19641312 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 19641312 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC
Study 17317676 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17317676 — Biomarker: CDKN1B mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN1B; KIP1; p27
Study 15851147 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 7819101 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 31954696 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 27424313 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12670780 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 1895369 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)