AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 8918498 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 3304725 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 24878174 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 20175241 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20175241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17272962 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17272962 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7843751 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26315981 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19429471 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 15158344 — Biomarker: HFE mRNA
Type: Predictive Biomarker (PRD)
Genes: HFE; HLAH
Study 15158344 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 9278211 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 9278211 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9278211 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 3495027 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 22951500 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11130773 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 7957160 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24694794 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21054850 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 15947724 — Biomarker: STAR mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAR; STARD1
Study 10686834 — Biomarker: TP53INP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TP53INP1; P53DINP1; SIP
Study 8850174 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 1928808 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 1928808 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1928808 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1928808 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29063307 — Biomarker: P4HB mRNA
Type: Predictive Biomarker (PRD)
Genes: P4HB; ERBA2L; PDI; PDIA1; PO4DB
Study 29786356 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29786356 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29786356 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15691303 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 12609711 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 1683217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25577201 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25577201 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16313112 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10588093 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30367320 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26561301 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 19054024 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 15136504 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study 15136504 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29570475 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26272328 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23299763 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18241359 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 18241359 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 12639160 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19686437 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 10526909 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12373040 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 7247587 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22948036 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 4068909 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22940436 — Biomarker: TMEM11 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMEM11; C17orf35; PM1
Study 12691375 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 8923833 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8923833 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 8923833 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 27627192 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 24393349 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 24393349 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20339359 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 20339359 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12358231 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 30045259 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30045259 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 23024015 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20673353 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18486740 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 25826885 — Biomarker: ATF7 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATF7; ATFA
Study 12136395 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12136395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 489201 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28317287 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 28317287 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 21221987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19961455 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9655746 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 335516 — Biomarker: RTEL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RTEL1; C20orf41; KIAA1088; NHL
Study 27709313 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27709313 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study 25133860 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19114862 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8707075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14693730 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 29729427 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 24160850 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 24160850 — Biomarker: RARA mRNA
Type: Predictive Biomarker (PRD)
Genes: RARA; NR1B1
Study 24160850 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9793253 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19427180 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16864724 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12934420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7949548 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3668883 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15269990 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 27030575 — Biomarker: TSTD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSTD1; KAT
Study 12521974 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22689695 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 30696336 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29261439 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 29261439 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 29261439 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 29261439 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 24777114 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12082591 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 28614793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19517101 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 9762777 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31676670 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 16990155 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12212248 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 3932470 — Biomarker: Succinate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: SDHD
Study 27062041 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27062041 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22812731 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17585003 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 7992988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7992988 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30655568 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 30655568 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 30655568 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30655568 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28407735 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9665109 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 361988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24647318 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 8110435 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2944688 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 27678295 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19940012 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18981327 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18981327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10622084 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8075589 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 8075589 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 8075589 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 8075589 — Biomarker: CD7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD7
Study 23242004 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 23242004 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 17080254 — Biomarker: L-acetylcarnitine
Type: Safety Biomarker (SAF)
Study 31170412 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25421542 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25421542 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 14732882 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 1599343 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30723140 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 30723140 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30723140 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 30723140 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 22623022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19389019 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study 2947874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26105554 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24769306 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 24769306 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24769306 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21397720 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 21397720 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 21397720 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11261274 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 6282024 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 6282024 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 6282024 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19444142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17464949 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 8730122 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8730122 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8730122 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25545309 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 12528101 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27864694 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17575470 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7911266 — Biomarker: IFT122 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFT122; SPG; WDR10; WDR140
Study 26358375 — Biomarker: HFE mRNA
Type: Predictive Biomarker (PRD)
Genes: HFE; HLAH
Study 25547339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23797811 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 3354444 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21740570 — Biomarker: DPT mRNA
Type: Predictive Biomarker (PRD)
Genes: DPT
Study 7980764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25163498 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25163498 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25163498 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30919377 — Biomarker: LARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LARS1; KIAA1352; LARS
Study 23390999 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 11179530 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1884902 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1884902 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 28125095 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 22883004 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 2871486 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31145180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26600017 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 21611754 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24467642 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24467642 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21875783 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study 17945069 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26056856 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 17767800 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8857512 — Biomarker: PDXP mRNA
Type: Predictive Biomarker (PRD)
Genes: PDXP; CIN; PLP; PLPP
Study 6476299 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30474740 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30474740 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29937430 — Biomarker: SLC5A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A1; NAGT; SGLT1
Study 29937430 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 27085076 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 27085076 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22128082 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31773485 — Biomarker: SLC39A13 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC39A13; ZIP13
Study 31773485 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29157592 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23537980 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15848534 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 27965111 — Biomarker: Connecting peptide
Type: Safety Biomarker (SAF)
Genes: AHSG; FETUA; PRO2743
Study 11325074 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11325074 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11325074 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7956637 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28737251 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24022862 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23757053 — Biomarker: IGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF2; PP1446
Study 20733306 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 19053918 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 7772012 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7772012 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27989018 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16679098 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8822354 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22853865 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 20164809 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 30699446 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 1959887 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 26934084 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 26934084 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17495205 — Biomarker: NES mRNA
Type: Predictive Biomarker (PRD)
Genes: NES; Nbla00170
Study 14630619 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 29703576 — Biomarker: HRC mRNA
Type: Predictive Biomarker (PRD)
Genes: HRC; HCP
Study 21186071 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 18316562 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18316562 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16179584 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16179584 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885