AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 27168572 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25023055 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22613532 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18224311 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 8025966 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31914556 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 31914556 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31914556 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23571719 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9407640 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 9407640 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28112467 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 24602091 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15243303 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15243303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14602747 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10951436 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 8797398 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 6706302 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 22445475 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 1898434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31776726 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 31531572 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3537019 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 23628502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17163239 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17163239 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 9106905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21911655 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 9086315 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9086315 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 9086315 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23937688 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 17295714 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 9207281 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12819249 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12819249 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 12819249 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 8194433 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8194433 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8194433 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11440284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3076136 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16912024 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14685864 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 23500091 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11550733 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11550733 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 3293400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27718000 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 27718000 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 22466026 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 9657471 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 9657471 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 10829905 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21409399 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18620827 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 11375295 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1760535 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7046411 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 28450529 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28450529 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 28450529 — Biomarker: Angiopoietin-1
Type: Monitoring Biomarker (MOI)
Genes: ANGPT1; KIAA0003
Study 28450529 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 23425517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10573242 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 3987929 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 31912903 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 12588325 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 12588325 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8247917 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17468862 — Biomarker: ABCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 23526939 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 23526939 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2050833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26778138 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11293751 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 17989918 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15175633 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15175633 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9719049 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7654109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31920107 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31002638 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31002638 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31002638 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19456003 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9160197 — Biomarker: CTLA4
Type: Predictive Biomarker (PRD)
Genes: CD152; CD; GSE; CTLA-4
Study 8125425 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8125425 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 31545914 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31545914 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 26881934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18490931 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15986036 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 15986036 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 9988393 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 7574193 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1689417 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31161927 — Biomarker: MMRN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 28550195 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 26081815 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6367533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7541064 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29901635 — Biomarker: SQSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SQSTM1; ORCA; OSIL
Study 29901635 — Biomarker: TARDBP mRNA
Type: Predictive Biomarker (PRD)
Genes: TARDBP; TDP43
Study 24793669 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 31492016 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 27040515 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 17503747 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7472824 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 31826009 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 28323139 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28323139 — Biomarker: Urokinase plasminogen activator surface receptor
Type: Monitoring Biomarker (MOI)
Genes: PLAUR; MO3; UPAR
Study 28323139 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 7926910 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 17006746 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10702171 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26081662 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 26081662 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 18598160 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 19657788 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19657788 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9972338 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3149455 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 29338146 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 29338146 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29338146 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16970093 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16970093 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16970093 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27364603 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 24731917 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12817518 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 12817518 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 12817518 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 10937516 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7522529 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 23736797 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 8299884 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8299884 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18834823 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8045488 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31189686 — Biomarker: SRM mRNA
Type: Predictive Biomarker (PRD)
Genes: SRM; SPS1; SRML1
Study 16505510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8418030 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8418030 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20622033 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 12564659 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 1320131 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 24721127 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14500805 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14500805 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 2666140 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23799751 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 18292453 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16531162 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21091062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21091062 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12626972 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 8457236 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 30893271 — Biomarker: CD101 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD101; EWI101; IGSF2; V7
Study 29954403 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 25623883 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 25623883 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15998769 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15998769 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8602658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1777174 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7324943 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31454197 — Biomarker: CPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPB1; CPB; PCPB
Study 23413781 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9620911 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 2668247 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 324566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29415833 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 29415833 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29415833 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 23816726 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 29452603 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 16402604 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8061263 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 22398345 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9212478 — Biomarker: SRY mRNA
Type: Predictive Biomarker (PRD)
Genes: SRY; TDF
Study 30737889 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29364091 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29364091 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 29364091 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10908213 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 9156659 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7798818 — Biomarker: MAP3K10 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP3K10; MLK2; MST
Study 24678979 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 24678979 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24678979 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31461862 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20565953 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 17407241 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2008870 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2008870 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23403068 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 22000309 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11422014 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 8536521 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 15236012 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26083700 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 19663929 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 18617745 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 12788888 — Biomarker: MENT mRNA
Type: Predictive Biomarker (PRD)
Genes: MENT; C1orf56; UNQ547/PRO1104
Study 12788888 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24629400 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24629400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17519714 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25968007 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 14999200 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10705305 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8565536 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8565536 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 1759835 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 23339040 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 11942472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2679288 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29411724 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 26367239 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 20846715 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20846715 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24260122 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 11566619 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11566619 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8059693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29121326 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 15273918 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11500195 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 21835280 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21835280 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 26881447 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 25919121 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 23650294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18222192 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 12675866 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12675866 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10963287 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 29193563 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 29193563 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25020061 — Biomarker: ULK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ULK1; KIAA0722
Study 25020061 — Biomarker: TRIM63 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 20864555 — Biomarker: HSPA1B mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA1B; HSP72
Study 1336527 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6518669 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)