AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24599421 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23363992 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 9551752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7528129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30100558 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 18256071 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12195132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12195132 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29565951 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29565951 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27436880 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22776095 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 22776095 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 16467067 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9814471 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24342715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17147835 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7706571 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 16159735 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 8673775 — Biomarker: APEX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 1438624 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 21393578 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 21393578 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 18339032 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 10873072 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31550800 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27817128 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10080457 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1310566 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20456060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27009433 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 27009433 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 27009433 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 27009433 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 27009433 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 11207642 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21506190 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 26853601 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26853601 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 26853601 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26486824 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 11319675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7943771 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7943771 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 7943771 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 7943771 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 7943771 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7943771 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 7943771 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 7943771 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31826232 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31826232 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31504126 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31504126 — Biomarker: HOXB13 mRNA
Type: Predictive Biomarker (PRD)
Genes: HOXB13
Study 31504126 — Biomarker: IL17RB mRNA
Type: Predictive Biomarker (PRD)
Genes: IL17RB; CRL4; EVI27; IL17BR; UNQ2501/PRO19612
Study 31504126 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 31504126 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11967798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24906822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22513516 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 8134718 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3306546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28177703 — Biomarker: MLEC mRNA
Type: Predictive Biomarker (PRD)
Genes: MLEC; KIAA0152
Study 26211765 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26211765 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26211765 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 10954004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10954004 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8660034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24694335 — Biomarker: CYP2R1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2R1
Study 24694335 — Biomarker: IRF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRF4; MUM1
Study 24694335 — Biomarker: MC1R mRNA
Type: Predictive Biomarker (PRD)
Genes: MC1R; MSHR
Study 24694335 — Biomarker: CYP27B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 24694335 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 24694335 — Biomarker: TYRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TYRP1; CAS2; TYRP; TYRRP
Study 24694335 — Biomarker: MCM6 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCM6
Study 24694335 — Biomarker: HERC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: HERC2
Study 23341518 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23341518 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20595800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8959150 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 4064565 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24604409 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15954952 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25122437 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 25122437 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 30998689 — Biomarker: CASZ1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CASZ1; CST; SRG; ZNF693
Study 30998689 — Biomarker: PPP3R1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPP3R1; CNA2; CNB
Study 30998689 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 30998689 — Biomarker: STIM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: STIM2; KIAA1482
Study 30998689 — Biomarker: HFE mRNA
Type: Predictive Biomarker (PRD)
Genes: HFE; HLAH
Study 30998689 — Biomarker: GATA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GATA2
Study 30998689 — Biomarker: NFATC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NFATC2; NFAT1; NFATP
Study 30998689 — Biomarker: SOX9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOX9
Study 30998689 — Biomarker: MICB mRNA
Type: Predictive Biomarker (PRD)
Genes: MICB; PERB11.2
Study 30998689 — Biomarker: CD209 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD209; CLEC4L
Study 6499702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20021517 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 8562399 — Biomarker: POU2F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: POU2F3; OTF11; PLA1
Study 30862658 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 28098097 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28098097 — Biomarker: Urinary total protein
Type: Safety Biomarker (SAF)
Study 26148204 — Biomarker: ABCC4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC4; MOATB; MRP4
Study 26148204 — Biomarker: CLDN10 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLDN10
Study 26148204 — Biomarker: SLC22A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A2; OCT2
Study 16179209 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2309991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31910030 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 12669742 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 2132640 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 443256 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 443256 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25729933 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23940710 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 15937757 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 28698692 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 25327485 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24502072 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21986123 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 29280043 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29145824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23542954 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 23542954 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study 9225527 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 8356591 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30304749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18987098 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30979507 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 23211012 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 10150222 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23739650 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20418097 — Biomarker: FCGR3A mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 20418097 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20418097 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 20418097 — Biomarker: CCND1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND1; BCL1; PRAD1
Study 20418097 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 16860921 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11864867 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 11864867 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 8886295 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 31094225 — Biomarker: FGFR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR2; BEK; KGFR; KSAM
Study 31094225 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 14710214 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 3936558 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 30107003 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 30107003 — Biomarker: IRF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRF4; MUM1
Study 21940766 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 21940766 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 12618584 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 12618584 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1343111 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29587662 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 20737166 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 16122072 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12100150 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12100150 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27716673 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 24030420 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 9075142 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23690533 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23690533 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23690533 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 23690533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15533351 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29455298 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 14685445 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11061985 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9490579 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3927690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30345884 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 30345884 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 27003517 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27003517 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27003517 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 27003517 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27003517 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 24461901 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 17272671 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9767255 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 24548447 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 20577103 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 18440181 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18440181 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6182412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8042821 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8042821 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17174637 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15955130 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15955130 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6932209 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 27919609 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 25676084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23591401 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 2889416 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29137091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15151265 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7698722 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 20632667 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10804023 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 1737453 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29302609 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 11751716 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30183438 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 15201246 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10914827 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 20053950 — Biomarker: Platelet-derived growth factor B
Type: Pharmacodynamic Biomarker (PDY)
Genes: PDGFB; PDGF2; SIS
Study 29355092 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26955678 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 22267464 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11772264 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2540757 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20177420 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 20177420 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 20177420 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 15580170 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 27662296 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 12968233 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 12968233 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12968233 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 30995657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30995657 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19536092 — Biomarker: ERCC5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC5; ERCM2; XPG; XPGC
Study 17825709 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1778353 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1778353 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10080677 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2833577 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 29169967 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29169967 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18942124 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15824216 — Biomarker: VIM mRNA
Type: Predictive Biomarker (PRD)
Genes: VIM
Study 8923161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1352949 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22759797 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20082236 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16234514 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16234514 — Biomarker: TOP2A mRNA
Type: Predictive Biomarker (PRD)
Genes: TOP2A; TOP2
Study 2191587 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2191587 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19304990 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29096069 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 29096069 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 26323598 — Biomarker: OGFRL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OGFRL1
Study 24705232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18039674 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 18039674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17209507 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8858057 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 31827687 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31827687 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT