AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 20940450 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17536194 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15180168 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 15180168 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3386506 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22218933 — Biomarker: FANCE mRNA
Type: Predictive Biomarker (PRD)
Genes: FANCE; FACE
Study 17347579 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1895263 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19406269 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 19406269 — Biomarker: TNFRSF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1A; TNFAR; TNFR1
Study 19406269 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19406269 — Biomarker: CASP9
Type: Predictive Biomarker (PRD)
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 15149341 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 11144997 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20874769 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 20874769 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1461956 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 21947428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9149200 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 26979520 — Biomarker: SLC29A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC29A4; ENT4; PMAT; PSEC0113
Study 22344611 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 15289797 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 11135086 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9853274 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31852749 — Biomarker: miR-34a
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR34A
Study 31852749 — Biomarker: miR-133b
Type: Safety Biomarker (SAF)
Genes: MIR133B
Study 28486474 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23278466 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 17461851 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15187512 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 15187512 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30337746 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20691837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18292286 — Biomarker: CXCL13 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL13; BCA1; BLC; SCYB13
Study 12634948 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28864226 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15170026 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 7663801 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 17103437 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14688492 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14688492 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10670837 — Biomarker: NFKBIA
Type: Predictive Biomarker (PRD)
Genes: IKBA; MAD-3; IkappaBalpha
Study 27866772 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17417133 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11485110 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11485110 — Biomarker: TNFR1B
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 21311063 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21311063 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17418554 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 15145911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23488491 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23488491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16454834 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 15237079 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 15622016 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 2899511 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29617504 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29617504 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27807041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23748506 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23748506 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1349028 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31475572 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 31475572 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31475572 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21105887 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 28024930 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 28024930 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 23866314 — Biomarker: RYR1
Type: Safety Biomarker (SAF)
Genes: RYR; PPP1R137
Study 23866314 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11096461 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 3533568 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28914562 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27600181 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15816573 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10619585 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 26050650 — Biomarker: IKZF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IKZF1; IK1; IKAROS; LYF1; ZNFN1A1
Study 21610711 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19628194 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19628194 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10333035 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19898645 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 26234623 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 15823293 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 2650700 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 69143 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8587456 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 8587456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28772048 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 28772048 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 23781136 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 21543343 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 11773285 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 8294090 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 22643350 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18514770 — Biomarker: UBC mRNA
Type: Predictive Biomarker (PRD)
Genes: UBC
Study 10868866 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 30570529 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 30570529 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 30570529 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 25415777 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2177614 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2177614 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19756557 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2964548 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31526307 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31526307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11136953 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9630383 — Biomarker: Plasma sitosterol and campesterol
Type: Surrogate Endpoint (SUR)
Study 19886856 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19886856 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7898078 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16022955 — Biomarker: ETV3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV3; METS; PE1
Study 20308916 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 18803987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15994073 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 7758229 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10403690 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 30896819 — Biomarker: DIAPH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DIAPH2; DIA
Study 30896819 — Biomarker: FOXN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXN3; C14orf116; CHES1
Study 30896819 — Biomarker: RHPN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RHPN1; KIAA1929
Study 30896819 — Biomarker: MEG3
Type: Predictive Biomarker (PRD)
Study 30701884 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 24686347 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11327625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9040452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3217992 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 3217992 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 30926293 — Biomarker: TPI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPI1; TPI
Study 17992639 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 7551664 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15608388 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 2565117 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28856913 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 18079261 — Biomarker: SLC16A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC16A4; MCT4; MCT5
Study 18079261 — Biomarker: MCTS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCTS1; MCT1
Study 3308702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29694685 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12655794 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 12655794 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7671437 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6776858 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 23305576 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 14986257 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 9203756 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 28417527 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 26605836 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11972594 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 9654837 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 28676038 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 26260553 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 10713659 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 8874676 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 22659998 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 18634770 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18634770 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7579383 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31035472 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 22302614 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21462082 — Biomarker: GMCL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GMCL2; GCL; GMCL1L; GMCL1P1
Study 16433867 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15569238 — Biomarker: CD109 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD109; CPAMD7
Study 11061579 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 17971487 — Biomarker: VIM mRNA
Type: Predictive Biomarker (PRD)
Genes: VIM
Study 17971487 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 12756503 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 8678062 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 29553033 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29084686 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 29084686 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29084686 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9714485 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14616414 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 14616414 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 14616414 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 3883170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3883170 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22801564 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17392729 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 17392729 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 17392729 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 16334158 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 12468959 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9382122 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1550171 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1550171 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22943970 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17332965 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 18800460 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21727232 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 14715339 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24747297 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 22089105 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22089105 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17233848 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 17233848 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1807007 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31647384 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30289287 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25795948 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25795948 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 19711135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30018370 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9589226 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2917924 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26082625 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 23365106 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 23365106 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23365106 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21274983 — Biomarker: SLCO1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 17053350 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29566095 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 26879069 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25915488 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25915488 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16882185 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8678277 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2932514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29807159 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23918683 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 23918683 — Biomarker: C-X-C motif chemokine 11
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 23918683 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC
Study 23918683 — Biomarker: CCL22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 10792094 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 8704686 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 23726175 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11686543 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22142767 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 12738015 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15917336 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19043252 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19043252 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12747340 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8580386 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 2550642 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23277250 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 23277250 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 16437269 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16437269 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 16437269 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16437269 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8681595 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 6395323 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 31074700 — Biomarker: PPARG mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARG; NR1C3