AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 29024499 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 26950082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24612659 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20398559 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23631443 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 19205723 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17284576 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12823645 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 12823645 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 8585003 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 22555112 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22555112 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20395648 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 16177676 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16177676 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7768585 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17096305 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9193008 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26519020 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24004475 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24004475 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12854176 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 29027715 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 20093623 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 20093623 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 20093623 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 20093623 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18565159 — Biomarker: CTLA4
Type: Predictive Biomarker (PRD)
Genes: CD152; CD; GSE; CTLA-4
Study 28860165 — Biomarker: SLC38A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC38A2; ATA2; KIAA1382; SAT2; SNAT2
Study 28860165 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 31143777 — Biomarker: DNMT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMT1; AIM; CXXC9; DNMT
Study 16709697 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 16709697 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16709697 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 15290418 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15290418 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15290418 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 11250190 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 8988994 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2364464 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 20192884 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 10203379 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 10203379 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10203379 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 23429588 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 23429588 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 17320023 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1401761 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 2416164 — Biomarker: PCLAF mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 25014007 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 25014007 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25014007 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10994627 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29224127 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24395436 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 9013270 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27173230 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 27173230 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 1978963 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 6794365 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 10669337 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30371182 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17533394 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 2961787 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25673113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21395644 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 16945613 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16945613 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 27461803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2734422 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25328957 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 18085502 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 14598874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31602579 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 25041859 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22241056 — Biomarker: CPT1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CPT1A; CPT1
Study 22241056 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 15145810 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 31525187 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21266950 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 21266950 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 31806605 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 23433349 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21812663 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 21812663 — Biomarker: Th2 cell
Type: Safety Biomarker (SAF)
Study 19627292 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11707629 — Biomarker: ALDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH2; ALDM
Study 24920884 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 24920884 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22383318 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20502447 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 15191507 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 31773776 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 28076735 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 21613350 — Biomarker: SOCS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOCS1; SSI1; TIP3
Study 21613350 — Biomarker: SOCS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOCS3; CIS3; SSI3
Study 9140907 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18249220 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18249220 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18249220 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11401114 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31969168 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16937281 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11828945 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 3033389 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3033389 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22581278 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 18575157 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9848888 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9848888 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22071384 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15578195 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 6365107 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6365107 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29340488 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24074360 — Biomarker: PNPLA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PNPLA3; ADPN; C22orf20
Study 21663597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19373239 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28256406 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19687610 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8438781 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30993587 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 28042070 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28042070 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12915959 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25532501 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 25532501 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25532501 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29410046 — Biomarker: NIBAN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NIBAN1; C1orf24; FAM129A; NIBAN; GIG39
Study 23104251 — Biomarker: CXCL16 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL16; SCYB16; SRPSOX; UNQ2759/PRO6714
Study 23104251 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 23104251 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11912265 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 18472682 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12873958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8917260 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29466116 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 29466116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29466116 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29466116 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 22383993 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 11880968 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7477806 — Biomarker: F7 mRNA
Type: Predictive Biomarker (PRD)
Genes: F7
Study 24973230 — Biomarker: F7 mRNA
Type: Predictive Biomarker (PRD)
Genes: F7
Study 21455059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16757527 — Biomarker: FMOD mRNA
Type: Predictive Biomarker (PRD)
Genes: FMOD; FM; SLRR2E
Study 15313211 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28003251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11468761 — Biomarker: Vitamin K-dependent protein C
Type: Safety Biomarker (SAF)
Genes: PROC
Study 2843031 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27774990 — Biomarker: TET2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET2; KIAA1546; Nbla00191
Study 23435671 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 19321570 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16296368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11912566 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9567633 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14982610 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 14982610 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23246796 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 18822021 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9360530 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 27512103 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 22008443 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 18055072 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9183496 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29283975 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21364957 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15324521 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15324521 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11208239 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7826297 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23808433 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 21605236 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19372172 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 15337017 — Biomarker: ESD mRNA
Type: Predictive Biomarker (PRD)
Genes: ESD
Study 11343523 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9552776 — Biomarker: TPI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPI1; TPI
Study 28775061 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28775061 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25532068 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31855207 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 22903545 — Biomarker: BTLA mRNA
Type: Predictive Biomarker (PRD)
Genes: BTLA
Study 22903545 — Biomarker: TNFRSF14 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF14; HVEA; HVEM; UNQ329/PRO509
Study 16506060 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 16506060 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 16506060 — Biomarker: CD53 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD53; MOX44; TSPAN25
Study 16506060 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23161092 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 518220 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 518220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2012448 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1496538 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6363949 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6363949 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23237135 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 21827318 — Biomarker: LGSN mRNA
Type: Predictive Biomarker (PRD)
Genes: LGSN; GLULD1; LGS
Study 14755134 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 14755134 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 3911699 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 16431933 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 10853679 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 3546747 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28731561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26695922 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 21252141 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21252141 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30580652 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 26835724 — Biomarker: FATE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FATE1; FATE
Study 20593911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30672832 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16368450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12449447 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8597321 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1912915 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30141966 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 27712932 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12193818 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29566443 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18413496 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18413496 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18413496 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15831773 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 15831773 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8998248 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25958079 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25958079 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 25958079 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25958079 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25958079 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23650950 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 23650950 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23650950 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 9445301 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 9445301 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 28685911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19015329 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 17314111 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11885871 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8167511 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 20145176 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8194495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18025536 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11292279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25970116 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25970116 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23234647 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23234647 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8221741 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22072084 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12540640 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10100068 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 10100068 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10100068 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1