AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 1345260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3974160 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10216810 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8582497 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30608872 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 20086201 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 30472318 — Biomarker: FANCE mRNA
Type: Predictive Biomarker (PRD)
Genes: FANCE; FACE
Study 25576879 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 22322513 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22322513 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 12395437 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7748985 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 2148224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26022239 — Biomarker: CDKN2A mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2A; CDKN2; MTS1
Study 26022239 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 26022239 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 26022239 — Biomarker: Retinoblastoma-associated protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: RB1
Study 17169762 — Biomarker: HDC mRNA
Type: Predictive Biomarker (PRD)
Genes: HDC
Study 15298795 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 1572111 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 4048886 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23849965 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21730029 — Biomarker: PTN mRNA
Type: Predictive Biomarker (PRD)
Genes: PTN; HBNF1; NEGF1
Study 21730029 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 21730029 — Biomarker: PPARG mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARG; NR1C3
Study 21730029 — Biomarker: PPARGC1A mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1
Study 17895513 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 17895513 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17895513 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 17349094 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15248628 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8956395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31647836 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 19056532 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 3782648 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 30722837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24842558 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15867404 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15867404 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12651685 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 12651685 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 2341828 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6376030 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31661346 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 29868916 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27843084 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 14574083 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 14574083 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 14574083 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24874737 — Biomarker: Synuclein alpha
Type: Pharmacodynamic Biomarker (PDY)
Genes: SNCA; NACP; PARK1
Study 22851072 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8618580 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23569301 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 31147243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29970139 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 23023905 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23023905 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23023905 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19778673 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19778673 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15132730 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 15132730 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15132730 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11488362 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 9733153 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2256489 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2256489 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23522152 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 4057126 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29283931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20491047 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7286051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7286051 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 7286051 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 26483221 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23554155 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15036568 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15036568 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23299526 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 16836503 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30978117 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 19640954 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11262775 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7994450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16840744 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15115092 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9167761 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9167761 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3026552 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3026552 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29696918 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 22698027 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22698027 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17879948 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 7860545 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7860545 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 1111368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31775404 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31775404 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 19791828 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 3104753 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 8967668 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1657221 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 22349765 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 16125534 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 16125534 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16125534 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 25200848 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17544857 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15060257 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 11023935 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30798568 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 11409225 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 27647263 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20643827 — Biomarker: Clusterin
Type: Safety Biomarker (SAF)
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 20643827 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 18984650 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 7796587 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2442560 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24430095 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23385792 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 15793163 — Biomarker: NAPA mRNA
Type: Predictive Biomarker (PRD)
Genes: NAPA; SNAPA
Study 8359565 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 2444797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2550243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8908893 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9607384 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2899108 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 31753745 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 11379804 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26074402 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 26074402 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23315596 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 23315596 — Biomarker: IGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF2; PP1446
Study 23315596 — Biomarker: IGFBP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP2; BP2; IBP2
Study 23315596 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 11717612 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 26397235 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22948049 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 22948049 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 31551393 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26955672 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26955672 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24743706 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 23146806 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23146806 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31533443 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 30311691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28419315 — Biomarker: LTA4H mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA4H; LTA4
Study 25240629 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 25240629 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 25240629 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17464237 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8709686 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25471276 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 19587642 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 19587642 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19587642 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 17802984 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15055997 — Biomarker: EDNRA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDNRA; ETA; ETRA
Study 22990619 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19781131 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17118669 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 7153164 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22265857 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 2964984 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2964984 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20186295 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 18844696 — Biomarker: CCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR1; CMKBR1; CMKR1; SCYAR1
Study 15964147 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 10373342 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 7756472 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23899008 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8572849 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8572849 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2467982 — Biomarker: NAPA mRNA
Type: Predictive Biomarker (PRD)
Genes: NAPA; SNAPA
Study 23266342 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23266342 — Biomarker: CCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR4; CMKBR4
Study 23266342 — Biomarker: CCRL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCRL2; CCR11; CCR6; CKRX; CRAM; HCR
Study 23266342 — Biomarker: CCR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 23266342 — Biomarker: CXCR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR3; GPR9
Study 30621517 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30621517 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10749622 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31210557 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 31210557 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18203890 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2003660 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15669595 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15669595 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7864430 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7864430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1685993 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1685993 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31974142 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 31974142 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 31974142 — Biomarker: Small-inducible cytokine A11
Type: Predictive Biomarker (PRD)
Genes: CCL11; SCYA11
Study 24647384 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7625773 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7625773 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7625773 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20413036 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 20413036 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17953462 — Biomarker: OGT mRNA
Type: Predictive Biomarker (PRD)
Genes: OGT
Study 15590244 — Biomarker: SSB mRNA
Type: Predictive Biomarker (PRD)
Genes: SSB
Study 20852079 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 19552597 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16381264 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8904056 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30920097 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 26655421 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 19240689 — Biomarker: Fibroblast growth factor 1
Type: Safety Biomarker (SAF)
Genes: FGF1
Study 10022444 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 7778470 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15906078 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 15906078 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 31829220 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 31829220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21141322 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 17413035 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 4499921 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31174395 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study 25927183 — Biomarker: CENPJ mRNA
Type: Predictive Biomarker (PRD)
Genes: CENPJ; CPAP; LAP; LIP1
Study 16879301 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 12556915 — Biomarker: DRD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD1
Study 21400543 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 21400543 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 20074465 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 3152400 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 21366472 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10933269 — Biomarker: SLC38A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 7504134 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7504134 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20568023 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 17566112 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 17566112 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16032449 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1827021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1827021 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12505243 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 7623373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7623373 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22403202 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10443654 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 29211013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12182690 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 12182690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8905281 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 1653883 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1