AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 17897105 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12688516 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31833102 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 24034663 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9333933 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8002621 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31421060 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28112681 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 28112681 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28112681 — Biomarker: TNF-related weak inducer of apoptosis
Type: Predictive Biomarker (PRD)
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study 18820779 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18820779 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24707022 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 20350619 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7781662 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 23478248 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 17449250 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 15386160 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8196289 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8196289 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24821586 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 22552566 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22552566 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20084279 — Biomarker: OAS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: OAS3; P/OKcl.4
Study 20084279 — Biomarker: SULF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SULF1; KIAA1077
Study 20084279 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 20084279 — Biomarker: DUT mRNA
Type: Predictive Biomarker (PRD)
Genes: DUT
Study 20084279 — Biomarker: TMC6 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMC6; EVER1; EVIN1
Study 20084279 — Biomarker: TMC8 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMC8; EVER2; EVIN2
Study 18711936 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 17045906 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31985746 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12461301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1861474 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1861474 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 23947690 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 23947690 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23947690 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23947690 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7977319 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7977319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31743394 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 22126894 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 20616786 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17289888 — Biomarker: PCA3
Type: Predictive Biomarker (PRD)
Study 15781340 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 15781340 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2540650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2540650 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 30528828 — Biomarker: S100A7 mRNA
Type: Predictive Biomarker (PRD)
Genes: S100A7; PSOR1; S100A7C
Study 23591293 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2667310 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28244906 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23510092 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 21223344 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11304902 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 7902021 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 29851569 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 27256922 — Biomarker: CD200R1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD200R1; CD200R; CRTR2; MOX2R; OX2R; UNQ2522/PRO6015
Study 23165467 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16630150 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 8349803 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8349803 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 27543252 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 21953589 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31876029 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 19660462 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19660462 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 19660462 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 17134849 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7880610 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 3709639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14730657 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9068935 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 9068935 — Biomarker: CYP3A4
Type: Safety Biomarker (SAF)
Genes: CYP3A3
Study 8415898 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 8415898 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 15637746 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9522242 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31444140 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15514192 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15514192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15514192 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2406228 — Biomarker: NOG mRNA
Type: Predictive Biomarker (PRD)
Genes: NOG
Study 6768079 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 24787908 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 24787908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31794968 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 28170279 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 25579717 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25579717 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25579717 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24016832 — Biomarker: FBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBP1; FBP
Study 9933475 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31738468 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 22414624 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 20506226 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 8707164 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 6133303 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6133303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29724865 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 18650514 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18262432 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18262432 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25908682 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19752472 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3422261 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 3422261 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30797045 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23456672 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17367356 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7657122 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15148064 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3548301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16269047 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12006915 — Biomarker: Serum alkaline phosphatase and bilirubin
Type: Surrogate Endpoint (SUR)
Study 19452376 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 15994253 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8686816 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8686816 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 6633131 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 28537652 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 28537652 — Biomarker: AFM mRNA
Type: Predictive Biomarker (PRD)
Genes: AFM; ALB2; ALBA
Study 11952509 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8587482 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 8587482 — Biomarker: ERCC8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC8; CKN1; CSA
Study 8587482 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2676872 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23221573 — Biomarker: FADS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS1; FADSD5
Study 23221573 — Biomarker: FADS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS2
Study 20666881 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10797611 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 8866385 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31722585 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 29231408 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20625026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16652049 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26410591 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 26410591 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11026626 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15820798 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15820798 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28049736 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28049736 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 28049736 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 28049736 — Biomarker: COL1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL1A1
Study 11216145 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11216145 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 29135601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26304156 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 22748043 — Biomarker: SPSB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPSB3; C16orf31; SSB3
Study 22748043 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 16287372 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 8950804 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24620913 — Biomarker: FBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBP1; FBP
Study 26016866 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21733046 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17229426 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12924797 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 6115521 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20090429 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20090429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16187917 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2223741 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 28504033 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 28504033 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25844857 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25844857 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16676705 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16676705 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 1514322 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31084656 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 21804061 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 14647985 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11707007 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24160205 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24160205 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 24160205 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 24160205 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16434427 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 2193461 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 6432398 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30580082 — Biomarker: miR-23a-3p
Type: Predictive Biomarker (PRD)
Genes: MIR23A
Study 30580082 — Biomarker: miR-16
Type: Safety Biomarker (SAF)
Study 30580082 — Biomarker: miR-146a
Type: Safety Biomarker (SAF)
Genes: MIR146A
Study 30580082 — Biomarker: miR-21
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR21
Study 16041193 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16041193 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10568224 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7725591 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 7725591 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7725591 — Biomarker: SIGLEC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIGLEC1; SN
Study 7725591 — Biomarker: TMEM37 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMEM37; PR
Study 31140343 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25214041 — Biomarker: CEBPA mRNA
Type: Predictive Biomarker (PRD)
Genes: CEBPA; CEBP
Study 22898992 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2686455 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2686455 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24356798 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 29683919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21467697 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19525846 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 8712429 — Biomarker: Auditory steady-state response
Type: Pharmacodynamic Biomarker (PDY)
Study 1888641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31327131 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28724799 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19896079 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15370080 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10840082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9338926 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9338926 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30642528 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 8681162 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28948296 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 3916511 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31752938 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25593907 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 20562693 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 18557810 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 12066724 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26709542 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 26709542 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25480994 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 25480994 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 25480994 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 18087554 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28625245 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28625245 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26028962 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study 15545203 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 27353719 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 21058480 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 7674293 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31129183 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15125719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28840583 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25573908 — Biomarker: APOL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOL1; APOL