AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 2930809 — Biomarker: PHLPP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PHLPP1; KIAA0606; PHLPP; PLEKHE1; SCOP
Study 328327 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study 23415672 — Biomarker: TIMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TIMP2
Study 23415672 — Biomarker: MMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP2; CLG4A
Study 23415672 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30577785 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 17848625 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 2643864 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2643864 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2643864 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21106710 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23147329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20545244 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12412675 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 27022941 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 11535842 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29903845 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18656328 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16301338 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10811043 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10811043 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25847473 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 15367189 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 16550750 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 1479003 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 29671368 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 20230403 — Biomarker: Arginase-1
Type: Safety Biomarker (SAF)
Genes: ARG1
Study 20230403 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 15655124 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7796586 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 1306851 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 1306851 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study 22327755 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18341756 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18341756 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8953203 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7138951 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28304242 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 28304242 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25651842 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 25651842 — Biomarker: Macrophage inflammatory protein 1-alpha
Type: Monitoring Biomarker (MOI)
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 25651842 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 9745994 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29177605 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16950285 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 11467759 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11467759 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11467759 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9575675 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 22088858 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16355341 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16355341 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 16355341 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 31912801 — Biomarker: TPI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPI1; TPI
Study 18953855 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 9273226 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9273226 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 1515386 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 22152974 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 15610835 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11594574 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9701719 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 9701719 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 27998910 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 27717532 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26413529 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28139023 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 23052568 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 19095857 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15526246 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30781485 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30781485 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30781485 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1937998 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23782555 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 17057609 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30416083 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 25048506 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 22901973 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22901973 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11573752 — Biomarker: MNT mRNA
Type: Predictive Biomarker (PRD)
Genes: MNT; BHLHD3; ROX
Study 9758087 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10649811 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10649811 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7073026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22460728 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 12055563 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 10663352 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22528813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28053275 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23219108 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23219108 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 21854503 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 21854503 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9383226 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9383226 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 3534869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8320744 — Biomarker: DHFR
Type: Safety Biomarker (SAF)
Genes: DHFR1
Study 18511016 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 12767369 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19095726 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19095726 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10996348 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 9024260 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 3310297 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30064491 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25952495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24030939 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19014494 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study 17147795 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14614165 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 14614165 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 14614165 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 11374857 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31591063 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31591063 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 29118087 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 21451504 — Biomarker: TLR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR7; UNQ248/PRO285
Study 26063688 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26063688 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19747937 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11408369 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 11408369 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 11408369 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 12847531 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12847531 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 29318656 — Biomarker: NPAS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NPAS2; BHLHE9; MOP4; PASD4
Study 24743880 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24743880 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11978262 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11978262 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28605609 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3058919 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 27923410 — Biomarker: DNMT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMT1; AIM; CXXC9; DNMT
Study 27923410 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 18334143 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16608935 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12911866 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11313239 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 9115157 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 21248446 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19064532 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23047713 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12742991 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 12742991 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9085015 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29490024 — Biomarker: MAG mRNA
Type: Predictive Biomarker (PRD)
Genes: MAG; GMA
Study 9288223 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 3554804 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 27924635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2454893 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 28680370 — Biomarker: AOX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AOX1; AO
Study 25869875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21212064 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 18788531 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18788531 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15893416 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 15893416 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 12610034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27287343 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 27287343 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 15486066 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2511910 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2511910 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24114402 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22315155 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 21980205 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 9778203 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7937860 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 2455114 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24777691 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11145109 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 9352757 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3596872 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26039521 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23222038 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 9279534 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27543277 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 27543277 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30118351 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 26313017 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 17786079 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17786079 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 15177521 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15177521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9498468 — Biomarker: CTBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CTBS; CTB
Study 9498468 — Biomarker: CLSTN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLSTN2; CS2
Study 9498468 — Biomarker: CLSTN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLSTN1; CS1; KIAA0911
Study 30789807 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 29018027 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17627016 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15899724 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 25524951 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14757693 — Biomarker: CPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPB1; CPB; PCPB
Study 11783697 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11783697 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10102907 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 594790 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 10451950 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2630295 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2630295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15607618 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 9291700 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 26674087 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 12437859 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10851564 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22019112 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21439539 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25814780 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 20886788 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20886788 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20886788 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10981087 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6366719 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6366719 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20038244 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17209957 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15616799 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 189334 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31288177 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 1782971 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 1782971 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 31940543 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 25095811 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28333551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25883031 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20032902 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11559318 — Biomarker: Ataxin-3
Type: Pharmacodynamic Biomarker (PDY)
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 3169108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25236582 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 19005898 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1616156 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6237623 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11546663 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 11546663 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11546663 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 29992026 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 29992026 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 29992026 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 15897552 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18089984 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30572979 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1459316 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1459316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25701070 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 20647958 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 17211497 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31164265 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31164265 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 15972357 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1