AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 22135319 — Biomarker: LY86 mRNA
Type: Predictive Biomarker (PRD)
Genes: LY86; MD1
Study 19841931 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 19841931 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12172327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10458542 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10458542 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20930708 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20930708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11682388 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 7948468 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 21142464 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9386661 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24780069 — Biomarker: ZPR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZPR1; ZNF259
Study 22375972 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 22402673 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17708612 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 14759393 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14759393 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29069359 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 15917338 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12891293 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12891293 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28799216 — Biomarker: MMD mRNA
Type: Predictive Biomarker (PRD)
Genes: MMD; PAQR11
Study 22542366 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 22542366 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 22542366 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 22542366 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16739369 — Biomarker: SEPTIN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEPTIN3; SEP3; SEPT3
Study 16739369 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 1354392 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1354392 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 1354392 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 28528475 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28528475 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28528475 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24946631 — Biomarker: SEMG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEMG1; SEMG
Study 25815710 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21852252 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15472792 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31916717 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 31215111 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31215111 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 27692128 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 17666196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29626378 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25218906 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 25218906 — Biomarker: FLT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT4; VEGFR3
Study 25218906 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 25210473 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 22362063 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 22362063 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 20622031 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12932605 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 12932605 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1910082 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20625319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12409741 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10374554 — Biomarker: USP9X mRNA
Type: Predictive Biomarker (PRD)
Genes: USP9X; DFFRX; FAM; USP9
Study 8195821 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21626050 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 2841552 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 384738 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31308037 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18692175 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 24755139 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24755139 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22922813 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22922813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10075387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2167800 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 30679107 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10606847 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 1289508 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18394499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12920631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12920631 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9224834 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 18206525 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14532151 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 8673528 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29904126 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19357997 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17453361 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2187945 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 10929741 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15882799 — Biomarker: GABRA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: GABRA5
Study 8568534 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 28029329 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 28029329 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28029329 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11981150 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9787687 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26727655 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24184245 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 22507330 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 19850848 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15612979 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 15612979 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1968178 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31162549 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 31162549 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9284426 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3561160 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18155056 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18155056 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12789263 — Biomarker: Ribonucleoside-diphosphate reductase large subunit
Type: Predictive Biomarker (PRD)
Genes: RRM1; RR1
Study 12789263 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 3653498 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27687359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25558561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22811032 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22811032 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15868655 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15868655 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9585778 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29072432 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 22136848 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22136848 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 23434737 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study 20350333 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16624552 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 16624552 — Biomarker: PDGFRA mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 10962114 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 1532316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23293333 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23293333 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23293333 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19567023 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17878255 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15268895 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 15268895 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 15268895 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12402413 — Biomarker: SSB mRNA
Type: Predictive Biomarker (PRD)
Genes: SSB
Study 10682131 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29017162 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 24973862 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19246729 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 8492409 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 31818531 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31818531 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30326548 — Biomarker: ALDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH2; ALDM
Study 23657296 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21290248 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 21290248 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 21290248 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 31937532 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 29739782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20200423 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 20200423 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 12032741 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27858912 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 27858912 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25189855 — Biomarker: EED mRNA
Type: Predictive Biomarker (PRD)
Genes: EED
Study 22473652 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 3303439 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3303439 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26542509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21621331 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16763334 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 29784592 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 22554354 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 10630736 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29351748 — Biomarker: LSS mRNA
Type: Predictive Biomarker (PRD)
Genes: LSS; OSC
Study 24557758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22089379 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8741025 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25330085 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16253600 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16253600 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11876795 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 11876795 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 7572740 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31416768 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 600190 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23284039 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 18851852 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16728220 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 11724639 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11724639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9390536 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2658575 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 2658575 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31482417 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1545669 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28464491 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 27504532 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27504532 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26084668 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 7527328 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9097297 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9097297 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 3080695 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 25040898 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 19897255 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26540314 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 26540314 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 26540314 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 22884381 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10206447 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8580383 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 31749182 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 17243139 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26581884 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 19933409 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11913598 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10190422 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17974421 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22112211 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7474246 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 25845393 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23868085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9397385 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3148789 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24345758 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 24345758 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 15356550 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 15356550 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 24395021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8108576 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 31201036 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 23166425 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 17503984 — Biomarker: TRIM32 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM32; HT2A
Study 29738877 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 21246842 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21246842 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18411016 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26027245 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9806026 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9806026 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 27101815 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 24675714 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 19177819 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10685331 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6740566 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 30587933 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30587933 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24864125 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24864125 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 17659194 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 12657846 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 25226307 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24395497 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 21465244 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27609756 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3001149 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19758824 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 15658649 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9950305 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7522017 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 7522017 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 1090174 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS