AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 27998224 — Biomarker: Cyclin-dependent kinase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CDK1; CDC2; CDC28A; CDKN1; P34CDC2
Study 23363041 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 18691228 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18691228 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16573545 — Biomarker: TRERF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRERF1; BCAR2; RAPA; TREP132
Study 8268900 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3082592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28929486 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28371482 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21693655 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 3880810 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 29925515 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 29925515 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29925515 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 23241505 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 23241505 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31645648 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 23336594 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 17347063 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19631948 — Biomarker: MYRF mRNA
Type: Predictive Biomarker (PRD)
Genes: MYRF; C11orf9; KIAA0954; MRF
Study 12503699 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 10519734 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 10519734 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7734901 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28500784 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 28301205 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 28301205 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 18299546 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12953165 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12953165 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10793603 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1282428 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 1282428 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 30642076 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30373740 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 30373740 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30373740 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 30373740 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12040477 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2548554 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21787159 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21787159 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19549125 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 26666342 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26666342 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26666342 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20642545 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17715164 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2523611 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 2523611 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 11249051 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 7940765 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21118164 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 18708685 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8870441 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 2000817 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25169631 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 17409306 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22453248 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 7675585 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27220348 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25218783 — Biomarker: miR-122
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR122
Study 15193818 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15193818 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15193818 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25529033 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25529033 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 27902612 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 12584575 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9690944 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8080985 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 2753986 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 20804630 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14983613 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30368584 — Biomarker: FGFR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR4; JTK2; TKF
Study 30368584 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study 29901710 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29901710 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18807577 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18807577 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18807577 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21106625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7945600 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12528545 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22763801 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11907289 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 11763947 — Biomarker: NAT9 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT9; EBS
Study 8964851 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29409728 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17432075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15910732 — Biomarker: GDA mRNA
Type: Predictive Biomarker (PRD)
Genes: GDA; KIAA1258
Study 7999930 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24521629 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22704426 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 28103841 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 28103841 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18783735 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 14740329 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 20482894 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16210834 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16210834 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29862491 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 25772196 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 17719702 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17719702 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7020917 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 26492082 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 26492082 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 24196866 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19777852 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19777852 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 22380577 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16160589 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30197644 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8018766 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22398880 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19684384 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10412851 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 2321778 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31921170 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30225882 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25439415 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25439415 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7341284 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 29571566 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22494623 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 20193521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23424215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10682136 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28544774 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 23313564 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 23313564 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 15975966 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10856268 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9379646 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 9379646 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 10908083 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 1471603 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6327758 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25417935 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 24350806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21981375 — Biomarker: OGT mRNA
Type: Predictive Biomarker (PRD)
Genes: OGT
Study 17726080 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 15922817 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1909273 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18341819 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16343101 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11382891 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11382891 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 11382891 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 11382891 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 7787395 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 21870665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11792410 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10626026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7485849 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31515735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30012822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18386234 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 479383 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16098067 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 16244488 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 176034 — Biomarker: NR3C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR3C2; MCR; MLR
Study 28540870 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28540870 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28540870 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26189154 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9543129 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10155484 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2724504 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 2724504 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24195206 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 16357613 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31172821 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 27459523 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 20304503 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 19029275 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10873425 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10873425 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 10873425 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 8884648 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8884648 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1857534 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 1857534 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31859138 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 26076757 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26112176 — Biomarker: EMP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EMP1; B4B; TMP
Study 23731922 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 7845867 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 31254481 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19129280 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 17472820 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15262126 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 10682563 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 2474097 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31371341 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 31371341 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 31371341 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 27893563 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27893563 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10617941 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 31344268 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29064536 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15906109 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 10516734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27407058 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10450297 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31341122 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 7572690 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 471153 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 471153 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 30680830 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29283132 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16883916 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 12832308 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 12832308 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8867520 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 1638712 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27394149 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 27394149 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18372701 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15164322 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31911640 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 3018561 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 29466862 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29466862 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 25564105 — Biomarker: COMMD3 mRNA
Type: Predictive Biomarker (PRD)
Genes: COMMD3; BUP; C10orf8
Study 16612281 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16612281 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27413037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29614521 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 29614521 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1556522 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 1556522 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25260632 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 22270198 — Biomarker: DCN mRNA
Type: Predictive Biomarker (PRD)
Genes: DCN; SLRR1B
Study 12776276 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 24284361 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 24284361 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22432114 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22432114 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 29275795 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 21925346 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25855628 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 22763799 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11596665 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11596665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25023798 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA