AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 26109079 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31693545 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 20383545 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 15841813 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 11045792 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 30139419 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19056575 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17634458 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17634458 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8909705 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19350378 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19350378 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31168845 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29521740 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 24519908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24519908 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19851772 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12134226 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9708400 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31587982 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31036337 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21455591 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29112001 — Biomarker: ISM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ISM1; C20orf82; ISM
Study 17883958 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 17883958 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 12411644 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 12411644 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 357455 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27838874 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28270498 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 11558484 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11558484 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11558484 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 27428476 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 21138476 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 21138476 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21138476 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21138476 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 21138476 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12913035 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8095779 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30825525 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 27001189 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20810159 — Biomarker: Apolipoprotein A-IV
Type: Monitoring Biomarker (MOI)
Genes: APOA4
Study 7780057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6244198 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10578225 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10578225 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31600397 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 31600397 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28391289 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6373154 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28033279 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 20833658 — Biomarker: GNB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNB3
Study 18821668 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2217349 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11350752 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9036201 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 8373897 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 29302744 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 18192897 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 18192897 — Biomarker: Alpha-1-acid glycoprotein 1
Type: Monitoring Biomarker (MOI)
Genes: ORM1; AGP1
Study 18192897 — Biomarker: IL18RAP mRNA
Type: Predictive Biomarker (PRD)
Genes: IL18RAP; IL1R7
Study 18192897 — Biomarker: FCGR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR2A; CD32; FCG2; FCGR2A1; IGFR2
Study 18192897 — Biomarker: PGGT1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PGGT1B
Study 8792796 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6486124 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29940668 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29940668 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 16325968 — Biomarker: LTB mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB; TNFC; TNFSF3
Study 3080101 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3080101 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 9008243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3549757 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24034658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12947433 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21419560 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26979712 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30595323 — Biomarker: HMGCR mRNA
Type: Predictive Biomarker (PRD)
Genes: HMGCR
Study 30595323 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30595323 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25039318 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 15755829 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 14749241 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29518432 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29518432 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29518432 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 16620333 — Biomarker: KY mRNA
Type: Predictive Biomarker (PRD)
Genes: KY
Study 517118 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 27379904 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18812659 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1976052 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24989688 — Biomarker: CCL26 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL26; SCYA26; UNQ216/PRO242
Study 24989688 — Biomarker: CCL24 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL24; MPIF2; SCYA24
Study 17644475 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26338890 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26338890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23670706 — Biomarker: BCL2L1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCL2L1; BCL2L; BCLX
Study 21516368 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21516368 — Biomarker: EDA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDA; ED1; EDA2
Study 29615049 — Biomarker: GATA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GATA3
Study 23279603 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29090731 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 21088973 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21088973 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11513305 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8582131 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 645073 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 23053764 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21739205 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16728551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10938022 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 10938022 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10938022 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30038151 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 18487744 — Biomarker: PPP6R2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPP6R2; KIAA0685; PP6R2; SAPS2
Study 7868973 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28899735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1495748 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 23445797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17522901 — Biomarker: PCLAF mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 11424663 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 6501724 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24213914 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 24213914 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 16758243 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 16758243 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 24591191 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12467997 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 31801712 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31801712 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 31801712 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31801712 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25291499 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25291499 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 25291499 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21798658 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 18465191 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 31395505 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31395505 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19537837 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 19537837 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15175438 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15175438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15175438 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27596801 — Biomarker: LSP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LSP1; WP34
Study 27596801 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 27596801 — Biomarker: FOXO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXO1; FKHR; FOXO1A
Study 22385118 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 22385118 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 8655902 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17935933 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31581926 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31581926 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26092821 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15677573 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 8767528 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 27634557 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25942487 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25942487 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 25882910 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19415820 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 19415820 — Biomarker: Coagulation factor Va
Type: Safety Biomarker (SAF)
Genes: F5
Study 19415820 — Biomarker: F7 mRNA
Type: Predictive Biomarker (PRD)
Genes: F7
Study 19415820 — Biomarker: F12 mRNA
Type: Predictive Biomarker (PRD)
Genes: F12
Study 8553675 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 8553675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12715685 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30541065 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17609490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23282123 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12751337 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3371847 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11948038 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 11948038 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22480275 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 7715294 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29493163 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 23328126 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23328126 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 21806837 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19836709 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 17086021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17086021 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9661649 — Biomarker: CYP21A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP21A2; CYP21; CYP21B
Study 22691828 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20831680 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20831680 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20831680 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20831680 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20831680 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20831680 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1382539 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 29746294 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29746294 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29746294 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 23924587 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23924587 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 8973871 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 24478399 — Biomarker: miR-140
Type: Safety Biomarker (SAF)
Genes: MIR140
Study 24478399 — Biomarker: miR-142
Type: Safety Biomarker (SAF)
Genes: MIR142
Study 24478399 — Biomarker: miR-423
Type: Safety Biomarker (SAF)
Genes: MIR423
Study 24478399 — Biomarker: miR-125b
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24478399 — Biomarker: miR-192
Type: Safety Biomarker (SAF)
Genes: MIR192
Study 24478399 — Biomarker: miR-195-5p
Type: Monitoring Biomarker (MOI)
Genes: MIR195
Study 16248984 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8789468 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 8789468 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 22271868 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19934286 — Biomarker: MAP2K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K1; MEK1; PRKMK1
Study 19934286 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 14660044 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 8251901 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2871185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22016263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18360186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8620703 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 31526108 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31526108 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 21163806 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 7703623 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1064725 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 31392401 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28290296 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20137594 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 20137594 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 25977995 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 23908160 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 10918945 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10918945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9405898 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20825715 — Biomarker: ADAM17 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM17; CSVP; TACE
Study 16988134 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 31732180 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 10730531 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8602477 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 1974628 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31559410 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22958738 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 17970234 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17970234 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 6158263 — Biomarker: NAPA mRNA
Type: Predictive Biomarker (PRD)
Genes: NAPA; SNAPA