AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 15250431 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 2764689 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2764689 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 2764689 — Biomarker: CALD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CALD1; CAD; CDM
Study 2764689 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9271771 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 29669938 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 16002074 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 16002074 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 12675716 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 10774784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8863775 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27100101 — Biomarker: MGP mRNA
Type: Predictive Biomarker (PRD)
Genes: MGP; MGLAP; GIG36
Study 27100101 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22918156 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7549379 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 9758084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28957940 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28957940 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 28957940 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28957940 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28957940 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17538167 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11600554 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11600554 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29668397 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 28347337 — Biomarker: MMD mRNA
Type: Predictive Biomarker (PRD)
Genes: MMD; PAQR11
Study 8379625 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 8379625 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 3021407 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23716067 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 1388048 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29028463 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 25418493 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25418493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11771598 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 11771598 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25257871 — Biomarker: ACACB mRNA
Type: Predictive Biomarker (PRD)
Genes: ACACB; ACC2; ACCB
Study 25257871 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 17094978 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 17094978 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 6529913 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11113398 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21145519 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21876043 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 7894066 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27704296 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27704296 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27704296 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 27704296 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24643920 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 19224159 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12149668 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31669329 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 31669329 — Biomarker: ETV5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV5; ERM
Study 28552710 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 15649674 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 7548266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7604800 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7604800 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20875945 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 18363889 — Biomarker: ADIPOR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOR2; PAQR2
Study 12941041 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8427238 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16247428 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 16247428 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16717297 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15058375 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 27916398 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 8061848 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30304326 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29210627 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23589771 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21525866 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21525866 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 31584766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23419459 — Biomarker: P2RX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: P2RX2; P2X2
Study 23419459 — Biomarker: P2RX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: P2RX1; P2X1
Study 22275250 — Biomarker: Synuclein alpha
Type: Pharmacodynamic Biomarker (PDY)
Genes: SNCA; NACP; PARK1
Study 16377699 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 29228087 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22382633 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 28584014 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21340560 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 10371376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7759224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30987577 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 21390978 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9385493 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 9385493 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 21599896 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 22879633 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 9709932 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 11973191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9465848 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9465848 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2118272 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 18946878 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 7043494 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 31118157 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31118157 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31118157 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23281216 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 30074872 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 30074872 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 30074872 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 25802309 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 16369855 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 12399736 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 27678425 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11901288 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10155349 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10155349 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 717750 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31354147 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17256759 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 9110940 — Biomarker: VIT mRNA
Type: Predictive Biomarker (PRD)
Genes: VIT; UNQ647/PRO1277
Study 31773582 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 30810457 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 25123196 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 27793072 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 12417537 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17472024 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26590495 — Biomarker: SNAP25 mRNA
Type: Predictive Biomarker (PRD)
Genes: SNAP25; SNAP
Study 17186332 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31992445 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 30334631 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21061562 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7615269 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 25380152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25380152 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 11673080 — Biomarker: Hypoxanthine-guanine phosphoribosyltransferase
Type: Safety Biomarker (SAF)
Genes: HPRT1; HPRT
Study 8988721 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 27895474 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27895474 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11850269 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10516938 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10516938 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 30073390 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30073390 — Biomarker: Tumor-infiltrating lymphocyte
Type: Predictive Biomarker (PRD)
Study 31634295 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31634295 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31634295 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 31634295 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10428106 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7484866 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19238303 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25599735 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25599735 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23917392 — Biomarker: SLC4A7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC4A7; BT; NBC2; NBC2B; NBC3; NBCn1; SBC2; SLC4A6
Study 18638309 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 18638309 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 18638309 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18638309 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7604809 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7604809 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31196132 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25232714 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25232714 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7972649 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28600210 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 28600210 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9786563 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2845188 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30919899 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30919899 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23764385 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 21343159 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 17609296 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 8547097 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21838784 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 21838784 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 18395908 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 11214351 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11214351 — Biomarker: Alpha-1-acid glycoprotein 1
Type: Monitoring Biomarker (MOI)
Genes: ORM1; AGP1
Study 8626351 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 1601510 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 1601510 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 1601510 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 20009917 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20009917 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20009917 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 20009917 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 20009917 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20009917 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1650015 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 6345596 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23203821 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 26205311 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 7943770 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17635246 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 11999236 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 204971 — Biomarker: EMB mRNA
Type: Predictive Biomarker (PRD)
Genes: EMB
Study 24696226 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25122429 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17126073 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17126073 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 15131468 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 7961258 — Biomarker: TEF mRNA
Type: Predictive Biomarker (PRD)
Genes: TEF; KIAA1655
Study 31920016 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 12712779 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 1424410 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30291012 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 30291012 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 30291012 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 30291012 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 18158708 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18158708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11808977 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24410993 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26912161 — Biomarker: G0S2 mRNA
Type: Predictive Biomarker (PRD)
Genes: G0S2
Study 26912161 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26912161 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26912161 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 14997024 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 14997024 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10664935 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 6442713 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 22494567 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19578132 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 19578132 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19578132 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11788107 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11788107 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7701577 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 7701577 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29198191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8888665 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1651213 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 6173522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31838486 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 11322056 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31548616 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16840514 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 16840514 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 31402562 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23640303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10843163 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25204191 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 25204191 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF