AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 10193713 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2148504 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25909149 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25909149 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 20965387 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 17853036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16027246 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16027246 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 10643800 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 8865536 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 8865536 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 29652271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22728005 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12406833 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 31434737 — Biomarker: FCGR2C mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR2C; CD32; FCG2; IGFR2
Study 31434737 — Biomarker: FCGR3B mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR3B; CD16B; FCG3; FCGR3; IGFR3
Study 31434737 — Biomarker: FCGR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR2A; CD32; FCG2; FCGR2A1; IGFR2
Study 31434737 — Biomarker: FCGR2B mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR2B; CD32; FCG2; IGFR2
Study 21280081 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 24709499 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24709499 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24709499 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15642068 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 12360165 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18386721 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 2567570 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 795564 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 22112293 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 10589810 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 23701746 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 15206062 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15206062 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7802176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4571186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19484680 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 23496988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17384437 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 15282005 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10972580 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 1569442 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 1569442 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 22074419 — Biomarker: HFE mRNA
Type: Predictive Biomarker (PRD)
Genes: HFE; HLAH
Study 22074419 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 22074419 — Biomarker: ALAD mRNA
Type: Predictive Biomarker (PRD)
Genes: ALAD
Study 29864432 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14624170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10072024 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8575576 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31199778 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 20015100 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 16303845 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15518626 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 111472 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 31294917 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25861158 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 21318594 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22956195 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 12953125 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 1419816 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26036987 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 21069380 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11703224 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11703224 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11703224 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 29701040 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29701040 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27396518 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27396518 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23902882 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 9331910 — Biomarker: SLC10A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC10A3; DXS253E; P3
Study 25038794 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 27529612 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22480803 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 20479938 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6250146 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23660319 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 23660319 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 2832102 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 2832102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28994661 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28994661 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 28994661 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 28994661 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 28994661 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 17885292 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15531667 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 26522742 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 10467215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7762265 — Biomarker: DPT mRNA
Type: Predictive Biomarker (PRD)
Genes: DPT
Study 30917258 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 30917258 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15145965 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 9588639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9588639 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 29724155 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 29724155 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 28363001 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 21670699 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 21670699 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 17374663 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17374663 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17374663 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 17374663 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 3295362 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20679179 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20679179 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 20679179 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17217690 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14674497 — Biomarker: TPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH1; TPH; TPRH; TRPH
Study 15553310 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18673555 — Biomarker: EPHA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPHA1; EPH; EPHT; EPHT1
Study 26842203 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26842203 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 16278521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12403667 — Biomarker: NE
Type: Predictive Biomarker (PRD)
Study 10442509 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 28762896 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25224993 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 25224993 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1945288 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 21890776 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10925934 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10925934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29653812 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 29653812 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29653812 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18281099 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 25217875 — Biomarker: TYMS
Type: Predictive Biomarker (PRD)
Genes: Tsase; TMS; HsT422
Study 20236598 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 20236598 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11876837 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 3891346 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 10155359 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10155359 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10155359 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 30874471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25845088 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25845088 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22404061 — Biomarker: SH2D1A mRNA
Type: Predictive Biomarker (PRD)
Genes: SH2D1A; DSHP; SAP
Study 20216298 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20216298 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20216298 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31553234 — Biomarker: Homologous recombination deficiency
Type: Predictive Biomarker (PRD)
Study 30249825 — Biomarker: UST mRNA
Type: Predictive Biomarker (PRD)
Genes: UST; DS2ST
Study 17336417 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 17336417 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 16341296 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 12015902 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12015902 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9562580 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 7947528 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3371393 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22373943 — Biomarker: GALR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GALR1; GALNR; GALNR1
Study 18235409 — Biomarker: NF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF2; SCH
Study 18235409 — Biomarker: WT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WT1
Study 9457906 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 232026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28240622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15577140 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15577140 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30799375 — Biomarker: PIR mRNA
Type: Predictive Biomarker (PRD)
Genes: PIR
Study 30799375 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 27279571 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21449785 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10052484 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7866820 — Biomarker: PLXNA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 11836674 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 16030123 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 16030123 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 8770775 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30578395 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 21030879 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21030879 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21030879 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 16943794 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16943794 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 1318081 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23868944 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 20544245 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11022900 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11022900 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1352564 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29602791 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 26582520 — Biomarker: STC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STC1; STC
Study 22325110 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11980678 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1597844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30264178 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26216382 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 26216382 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20712602 — Biomarker: MEA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MEA1; MEA
Study 31774950 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25867847 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 18317624 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27966508 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 17920365 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17920365 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7668935 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 2401750 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31789006 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15237694 — Biomarker: RFC1
Type: Safety Biomarker (SAF)
Genes: A1; PO-GA; RFC140; MHCBFB
Study 22776420 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22776420 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18266604 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 11416735 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30156200 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 30156200 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26363048 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 19012865 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 19012865 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 12902634 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11381293 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9142006 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9142006 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 16670077 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24392703 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 12509214 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 7891796 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7891796 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7891796 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8420311 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3736737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31810613 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study 27098150 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21123458 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 18355770 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 16310388 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 14567443 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 14567443 — Biomarker: MTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 14567443 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 1441789 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31295334 — Biomarker: PROCR mRNA
Type: Predictive Biomarker (PRD)
Genes: PROCR; EPCR
Study 9434647 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28846481 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 3117566 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19342295 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 27381263 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 1428302 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17671042 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 3187 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21813427 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 21813427 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 11378343 — Biomarker: TMEM37 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMEM37; PR
Study 29910024 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29910024 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 18713788 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30768224 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28576627 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 23980056 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22109762 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT