AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24797938 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 22569857 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 24020899 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11564829 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 24930619 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23444220 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21601481 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11565517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11565517 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3327677 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22709990 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18061415 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9103485 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 7942523 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 29196928 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 29196928 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23125290 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9203174 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 28060012 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25103870 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 29788732 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 23460714 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23460714 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 23460714 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 25632806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7030978 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31704050 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 31704050 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 31704050 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 30247967 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18230694 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 18230694 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 15163387 — Biomarker: TNFSF10 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF10; APO2L; TRAIL
Study 15163387 — Biomarker: TNFRSF10B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9; UNQ160/PRO186
Study 27231549 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12095381 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7671566 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 2111414 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 31415003 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11004863 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9486935 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9486935 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9486935 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19501213 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 19501213 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23563111 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14714769 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 14714769 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 30922373 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23416033 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17497591 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 11441422 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2252243 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30839302 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11711508 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28766132 — Biomarker: NCOA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NCOA3; AIB1; BHLHE42; RAC3; TRAM1
Study 28766132 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28766132 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12600850 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 11268452 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6397652 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 26946613 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26946613 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 15115904 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12239447 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9846584 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 8960727 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 18568800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30126559 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24448173 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 30889096 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17452677 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17452677 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 10440909 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 10440909 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 10440909 — Biomarker: SERPINA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 10440909 — Biomarker: PPIC mRNA
Type: Predictive Biomarker (PRD)
Genes: PPIC; CYPC
Study 10440909 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 10440909 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31774842 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19905943 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19905943 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 19905943 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2184002 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31670008 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 31670008 — Biomarker: CXADR mRNA
Type: Predictive Biomarker (PRD)
Genes: CXADR; CAR
Study 31670008 — Biomarker: ASPSCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 28356431 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19911216 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8154629 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26780085 — Biomarker: DKK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DKK1; UNQ492/PRO1008
Study 26780085 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22563948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27825388 — Biomarker: CYP19A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 27825388 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9527747 — Biomarker: SH2D1A mRNA
Type: Predictive Biomarker (PRD)
Genes: SH2D1A; DSHP; SAP
Study 9527747 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9527747 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25835438 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19423109 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 19423109 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 19423109 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17969367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11477813 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 7865804 — Biomarker: HBE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HBE1; HBE
Study 27678433 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 16075063 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 12461037 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10656205 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6685597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29066122 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 26935286 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26645514 — Biomarker: EDAR mRNA
Type: Predictive Biomarker (PRD)
Genes: EDAR; DL
Study 18243724 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6805243 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 23880826 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 23880826 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 23880826 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19659999 — Biomarker: UCP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP2; SLC25A8
Study 19659999 — Biomarker: ADRB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB3; ADRB3R; B3AR
Study 19659999 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2109497 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 2109497 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 16150195 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28139220 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 31888751 — Biomarker: LAMB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMB2; LAMS
Study 26833642 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26833642 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 25191896 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 21429799 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21429799 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21429799 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21429799 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 15264729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2108981 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 27428294 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 27428294 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 24460655 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 14700505 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study 28041917 — Biomarker: MCCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCCC2; MCCB
Study 16618976 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16618976 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8339411 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29723578 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 26597128 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 9175147 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8465780 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8465780 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3008669 — Biomarker: SMARCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMARCA2; BAF190B; BRM; SNF2A; SNF2L2
Study 31174600 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 26538364 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26538364 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26538364 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24863250 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study 22453866 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 10509550 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10509550 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24615681 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23047652 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 17957793 — Biomarker: PSCA mRNA
Type: Predictive Biomarker (PRD)
Genes: PSCA; UNQ206/PRO232
Study 1889697 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29861448 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24460863 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 2505627 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19506919 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 16681476 — Biomarker: SEPTIN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEPTIN3; SEP3; SEPT3
Study 11305707 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 9430805 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31965899 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22749707 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25884315 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 9610529 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8111257 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8111257 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26521106 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23599381 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 23599381 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 16807142 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 16807142 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 1576095 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19755656 — Biomarker: CHRNB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNB2
Study 16531621 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29633621 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29633621 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24390764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21430703 — Biomarker: Protein patched homolog 1
Type: Predictive Biomarker (PRD)
Genes: PTCH1; PTCH
Study 21430703 — Biomarker: SMO mRNA
Type: Predictive Biomarker (PRD)
Genes: SMO; SMOH
Study 9296729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8409079 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8409079 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28827788 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 28827788 — Biomarker: MMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP2; CLG4A
Study 28827788 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 22070512 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 17604453 — Biomarker: FUT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FUT1; H; HSC
Study 17604453 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 16097050 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31646767 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 11156490 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 11156490 — Biomarker: GRAMD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRAMD4; DIP; KIAA0767
Study 31250668 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26216477 — Biomarker: Lysosomal alpha-glucosidase
Type: Safety Biomarker (SAF)
Genes: GAA
Study 26216477 — Biomarker: ABL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABL2; ABLL; ARG
Study 26216477 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 17150221 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 17150221 — Biomarker: SLC25A20 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A20; CAC; CACT
Study 17150221 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15871847 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16321141 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 16321141 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8614310 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8614310 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2269032 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 29800130 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 24517173 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 10625114 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8749696 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 31176287 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 26405104 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 25493942 — Biomarker: WWTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WWTR1; TAZ
Study 18339792 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25324277 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 11134469 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7930234 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 2465447 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23423269 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11726257 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 8030688 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8030688 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2913773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2913773 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2124243 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 20491957 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15824342 — Biomarker: CA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA1
Study 1611832 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 29250843 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26054202 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 26054202 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 26054202 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 8470059 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31281181 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)