AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 10589361 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26921267 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17370037 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17370037 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9539583 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8586834 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2710909 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 902626 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25291152 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 7272896 — Biomarker: CNDP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNDP2; CN2; CPGL; HEL-S-13; PEPA
Study 30496024 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28270491 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 26797215 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 26797215 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11887193 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27803120 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26829443 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9855322 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 799958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31325802 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31325802 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21972626 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18390974 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18390974 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10407512 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 20567002 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 20567002 — Biomarker: MYCN mRNA
Type: Predictive Biomarker (PRD)
Genes: MYCN; BHLHE37; NMYC
Study 14633521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15839182 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11716200 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 30734583 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 18223492 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20102775 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20102775 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20102775 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9829540 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25080293 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 22396129 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 18525041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26863353 — Biomarker: ADAMTS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 26863353 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21422800 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 21422800 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 21422800 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 17323015 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 12172882 — Biomarker: HHEX mRNA
Type: Predictive Biomarker (PRD)
Genes: HHEX; HEX; PRH; PRHX
Study 9604124 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28454801 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 28454801 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26424460 — Biomarker: GSS mRNA
Type: Predictive Biomarker (PRD)
Genes: GSS
Study 23727422 — Biomarker: TLR9
Type: Predictive Biomarker (PRD)
Genes: CD289
Study 15653003 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8756735 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 26987975 — Biomarker: Fatty acid amide hydrolase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: FAAH; FAAH1
Study 22527063 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16901550 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 11427219 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26599707 — Biomarker: AGTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study 26599707 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 26599707 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 10227630 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 10227630 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 10227630 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7782581 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 23168581 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 23168581 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 23168581 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 20164296 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18478937 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25751447 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17653011 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17653011 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17653011 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 16671340 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30778518 — Biomarker: MMD mRNA
Type: Predictive Biomarker (PRD)
Genes: MMD; PAQR11
Study 26436683 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26436683 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 20732768 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20732768 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 20732768 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 3320785 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19590482 — Biomarker: GSS mRNA
Type: Predictive Biomarker (PRD)
Genes: GSS
Study 16876164 — Biomarker: BSG mRNA
Type: Predictive Biomarker (PRD)
Genes: BSG; UNQ6505/PRO21383
Study 6463598 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 30802196 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30802196 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 30802196 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 30802196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28619016 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14709941 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 21816979 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 19890022 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19890022 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17048576 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29443823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15932366 — Biomarker: Trefoil factor 3
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TFF3; ITF; TFI
Study 10583036 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8904726 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27354646 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23247938 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10475722 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30726969 — Biomarker: HCAR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: HCAR2; GPR109A; HCA2; HM74A; NIACR1
Study 30726969 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27821724 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 16396628 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 10493476 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31863227 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30266356 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 20460116 — Biomarker: PCLAF mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 11231856 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 11231856 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2455778 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 30799192 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19441668 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 16687967 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14728846 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 14728846 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 10775075 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 31665017 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22920048 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20519552 — Biomarker: SLC47A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC47A1; MATE1
Study 20519552 — Biomarker: MATE1
Type: Safety Biomarker (SAF)
Genes: SLC47A1; FLJ10847
Study 17602170 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 15074091 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11677003 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2768768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25328079 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 25328079 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 24942407 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 21147691 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17991545 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 8903900 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 1708910 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 28973620 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 28973620 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 28973620 — Biomarker: CYP4F2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP4F2
Study 12554614 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8857018 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8857018 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31145689 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 28462892 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17109346 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 10775074 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8990355 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8931848 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31388739 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15723969 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15723969 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2345633 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 26803355 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20411995 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12651051 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 10824717 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 6323866 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18407341 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10100178 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 8889353 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1905631 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7104149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30650288 — Biomarker: MAP3K7 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP3K7; TAK1
Study 30650288 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30650288 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30650288 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16279916 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 6636033 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6636033 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 30399034 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19043656 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8848888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30999963 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12742557 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20185637 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 16322336 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8541695 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 31812554 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 25845768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23379590 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21113641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31944420 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 20556561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10229292 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10229292 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21377930 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 2842146 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 26571884 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 26275164 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16436892 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19894018 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7851599 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 19004549 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 19004549 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 2117858 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 2117858 — Biomarker: TMEM37 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMEM37; PR
Study 26602322 — Biomarker: CPD mRNA
Type: Predictive Biomarker (PRD)
Genes: CPD
Study 22579409 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 26790823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19169140 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19952819 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1817663 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 24588434 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 9760009 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9760009 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8156094 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24895108 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 21141289 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 17590511 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3511382 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27789050 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 27789050 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 27789050 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 30508316 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22151836 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22151836 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15595588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30007054 — Biomarker: FGG mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGG; PRO2061
Study 25953073 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 18316791 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 18316791 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 6166800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26176605 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 19168521 — Biomarker: ACOT7 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACOT7; BACH
Study 9209608 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3623678 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 3623678 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19247742 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15229391 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 19117887 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16937109 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 25122693 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 17454163 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 10541948 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 10541948 — Biomarker: SLC35A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC35A2; UGALT; UGT; UGTL
Study 2129071 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26993316 — Biomarker: UCP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP1; SLC25A7; UCP
Study 27779565 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27779565 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 23999661 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 22165459 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18998188 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 18998188 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15233286 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 8929232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28347792 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28347792 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28347792 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2