AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 18304285 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 18304285 — Biomarker: SEPTIN6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEPTIN6; KIAA0128; SEP2; SEPT6
Study 18304285 — Biomarker: SEPTIN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEPTIN3; SEP3; SEPT3
Study 26250833 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 26250833 — Biomarker: CFTR
Type: Predictive Biomarker (PRD)
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 23218065 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21349192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19047545 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8155409 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22538186 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17038074 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 9375336 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3236329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29687553 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 3140592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26125448 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 18253905 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 17175820 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25418492 — Biomarker: PTPRF mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRF; LAR
Study 25418492 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25418492 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23687222 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 23687222 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 20502415 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18426826 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12865039 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25171042 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 7315774 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7315774 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 29633367 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 27897610 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23989533 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11802037 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 11802037 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 11802037 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 11802037 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11802037 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 10391281 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 9351353 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26233481 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21527567 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study 18815937 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3536231 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16735449 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8140941 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29537903 — Biomarker: TNFRSF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1A; TNFAR; TNFR1
Study 29537903 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 29537903 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24094907 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 19234845 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19234845 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17620776 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 520397 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21529314 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18480967 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 17121193 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25512256 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 29253140 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 11387501 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10821345 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1452929 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22152080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17494679 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 30991881 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23271615 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 23271615 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 23271615 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29359279 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28692770 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20038957 — Biomarker: SULT1C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SULT1C2; SULT1C1
Study 20038957 — Biomarker: CHST3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHST3
Study 20038957 — Biomarker: SPG7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPG7; CAR; CMAR; PGN
Study 20038957 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 20038957 — Biomarker: ABCC6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC6; ARA; MRP6
Study 20038957 — Biomarker: ATP7A mRNA
Type: Predictive Biomarker (PRD)
Genes: ATP7A; MC1; MNK
Study 10745332 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30831541 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 30831541 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25368202 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23549824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16673249 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16673249 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 9324340 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 18024166 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8781005 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 26248047 — Biomarker: PGP mRNA
Type: Predictive Biomarker (PRD)
Genes: PGP
Study 19606937 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4898 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27830967 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 25915168 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 25915168 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25915168 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2478790 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2478790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20459012 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 15691863 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12665638 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26603110 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 26603110 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24884504 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 2190504 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 12037733 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24903467 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20837942 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 20837942 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 11817501 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25077418 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 16126118 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16126118 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10408666 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27937077 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27937077 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21632072 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19497091 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11488772 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 9138439 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10213434 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 29498351 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26224203 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 26224203 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 24625755 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24625755 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 22484031 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23645763 — Biomarker: MHC class I polypeptide-related sequence A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MICA; PERB11.1
Study 23645763 — Biomarker: KLRK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRK1; D12S2489E; NKG2D
Study 23645763 — Biomarker: GLIS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLIS2; NKL
Study 23645763 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 9475648 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8582538 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 2215098 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 380941 — Biomarker: DSP mRNA
Type: Predictive Biomarker (PRD)
Genes: DSP
Study 30207586 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 19153580 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19153580 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9764962 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 23527013 — Biomarker: TRIM27 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM27; RFP; RNF76
Study 23527013 — Biomarker: CD83 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD83
Study 23527013 — Biomarker: CETN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CETN3; CEN3
Study 17440528 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 17440528 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10972368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26988798 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26988798 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26988798 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26988798 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23444397 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21253392 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12678277 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 12678277 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 1397674 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26714287 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 22572418 — Biomarker: RHD mRNA
Type: Predictive Biomarker (PRD)
Genes: RHD
Study 18047921 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18047921 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 18047921 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8750365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8750365 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 8750365 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8750365 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 25317545 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20353028 — Biomarker: LSR mRNA
Type: Predictive Biomarker (PRD)
Genes: LSR; ILDR3; LISCH
Study 9928755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6756418 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14694168 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2656860 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2656860 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28255731 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21498786 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16989902 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 22507791 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 22507791 — Biomarker: CES2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CES2; ICE
Study 15967223 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 31907007 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28745674 — Biomarker: KRIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KRIT1; CCM1
Study 28745674 — Biomarker: CCM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCM2; C7orf22; PP10187
Study 21386706 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28355317 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21862934 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17320090 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 17320090 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 17320090 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17320090 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12575392 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 7874375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31675993 — Biomarker: NR3C1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR3C1; GRL
Study 31675993 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22581292 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9135733 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 7698130 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12671890 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 30912767 — Biomarker: LEF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LEF1
Study 30912767 — Biomarker: FasL mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: FASLG; APT1LG1; CD95L; FASL; TNFSF6
Study 30912767 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 15700313 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 10844380 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7552520 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17639748 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17639748 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 31640977 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23675619 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19526754 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 17338713 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16422810 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 16422810 — Biomarker: SEPTIN6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEPTIN6; KIAA0128; SEP2; SEPT6
Study 16422810 — Biomarker: SEPTIN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEPTIN3; SEP3; SEPT3
Study 10381294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 500834 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28005225 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study 2354484 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27503851 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27503851 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23009149 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21077572 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 11828246 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11828246 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 2310247 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 28109295 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 28109295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11153017 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 11153017 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20852881 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18367379 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 9104860 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2486782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23021155 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22036523 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 22036523 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22036523 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 22036523 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 22036523 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22036523 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16998289 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22947545 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 25603432 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 25603432 — Biomarker: NEB mRNA
Type: Predictive Biomarker (PRD)
Genes: NEB
Study 19487177 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15152060 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21806572 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16684279 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 16684279 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 9224961 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7737957 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 24843061 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 24843061 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18052556 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 25867415 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11337977 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11337977 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29544472 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 26856220 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24694337 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG