AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 29386335 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20594395 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20594395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12418945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12418945 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7737719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7021994 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 23603204 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 21093145 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 19275490 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 19275490 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 19275490 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 19275490 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1921253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6354604 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18822974 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 18822974 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 10606107 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 17959958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31126331 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 17909201 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 27290958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22538219 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 30576866 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15167310 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 282081 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21917481 — Biomarker: GAL3ST1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAL3ST1; CST
Study 31848294 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 31848294 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 18194116 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18194116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31985301 — Biomarker: WWTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WWTR1; TAZ
Study 26990279 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 23937421 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23937421 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17430984 — Biomarker: LIFR mRNA
Type: Predictive Biomarker (PRD)
Genes: LIFR
Study 1352246 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30037035 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23625867 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 15867235 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 15867235 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15867235 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30893060 — Biomarker: C-X-C motif chemokine 5
Type: Safety Biomarker (SAF)
Genes: CXCL5; ENA78; SCYB5
Study 30893060 — Biomarker: SIRT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIRT2; SIR2L; SIR2L2
Study 30893060 — Biomarker: AXIN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AXIN1; AXIN
Study 28931981 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23288035 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 8614385 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 1451343 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 7617817 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 1975483 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15907417 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 15907417 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 9806660 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10649920 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 31358017 — Biomarker: ZFYVE9 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZFYVE9; MADHIP; SARA; SMADIP
Study 28686822 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 21448303 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18502257 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15673893 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 9024515 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 7862826 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2890591 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15860688 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 31694220 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31694220 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14683738 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9468065 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7893035 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 2575480 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28535400 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 21243736 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10764900 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23044768 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21039208 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19576339 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 2900132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31019123 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 15229392 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18191645 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31532137 — Biomarker: LSS mRNA
Type: Predictive Biomarker (PRD)
Genes: LSS; OSC
Study 26467531 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 26467531 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 26467531 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 26467531 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26467531 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 26467531 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 7964860 — Biomarker: ABCD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCD1; ALD
Study 31301533 — Biomarker: RHD mRNA
Type: Predictive Biomarker (PRD)
Genes: RHD
Study 19842940 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 19842940 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 10972632 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10972632 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12580211 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 1612530 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 24388920 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 8501579 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31958337 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 27922950 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 23187726 — Biomarker: PAG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAG1; CBP; PAG
Study 21996393 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 14676787 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 3752487 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 31658396 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 27891663 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 27891663 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25686055 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21527519 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 1642185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6463180 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 22343483 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 8637449 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 8637449 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 8637449 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 2206032 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22170972 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 10465068 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7494809 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31731005 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 31093755 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study 31093755 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 18785846 — Biomarker: PCSK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK5; PC5; PC6
Study 16626571 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11239180 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 2497096 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 21989542 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20979784 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16093464 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31864339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28738008 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 25941765 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 25941765 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25941765 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 20165628 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17445432 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29966645 — Biomarker: PPIC mRNA
Type: Predictive Biomarker (PRD)
Genes: PPIC; CYPC
Study 29966645 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 22777936 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22777936 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15735611 — Biomarker: SLCO1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 8856481 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16682304 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 16682304 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1854047 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 1854047 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29181852 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 24225449 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12153743 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 19075055 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 11468148 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 3139571 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 15534491 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24373369 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 24373369 — Biomarker: PGAM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PGAM1; PGAMA; CDABP0006
Study 24373369 — Biomarker: AZGP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AZGP1; ZAG; ZNGP1
Study 24373369 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 25007091 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 22311342 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25705899 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 11304861 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 9398099 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28736918 — Biomarker: Dermal blood flow
Type: Pharmacodynamic Biomarker (PDY)
Study 24834772 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 24834772 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16012002 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30500558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11157331 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 11157331 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11157331 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15716710 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15716710 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22549600 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 14516881 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 1987006 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6846125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25623520 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25623520 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15211441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15211441 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15211441 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9156934 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 9156934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1860199 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 18156990 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12640021 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19541503 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19541503 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20368475 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15668361 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12544691 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 227680 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 227680 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 19720911 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 19720911 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 12185892 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30694972 — Biomarker: REST mRNA
Type: Predictive Biomarker (PRD)
Genes: REST; NRSF; XBR
Study 23192919 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23192919 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8674923 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 20873243 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 20873243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16351785 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 10361873 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 8572838 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8572838 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8572838 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29310989 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29310989 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24803302 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16926662 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11304719 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31492718 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 31836949 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 31836949 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23001685 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23001685 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 23001685 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 19245735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10831636 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10831636 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10831636 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25058680 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16109088 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7817807 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3287881 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 18288734 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 29438373 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 25706092 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18468955 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 16177196 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12668521 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study 1839125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6344896 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6344896 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 6344896 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 27841850 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22313729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20377925 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20377925 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12050252 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26387030 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24431462 — Biomarker: NRG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRG3
Study 23440680 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2199721 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24325104 — Biomarker: NGB mRNA
Type: Predictive Biomarker (PRD)
Genes: NGB
Study 24325104 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 19874474 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 19874474 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10