AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 11275936 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study 28930494 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 19809382 — Biomarker: TRAPPC9 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 31194613 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 18644399 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 27224474 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27224474 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 27224474 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19736368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17606774 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 11854876 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 11854876 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11854876 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7029294 — Biomarker: AADAC mRNA
Type: Predictive Biomarker (PRD)
Genes: AADAC; DAC
Study 30939480 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30939480 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25919263 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 24067390 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21851939 — Biomarker: LIF mRNA
Type: Predictive Biomarker (PRD)
Genes: LIF; HILDA
Study 21851939 — Biomarker: LIFR mRNA
Type: Predictive Biomarker (PRD)
Genes: LIFR
Study 21851939 — Biomarker: DKK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DKK1; UNQ492/PRO1008
Study 7641905 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7641905 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31563959 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31563959 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 31563959 — Biomarker: CDK6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK6; CDKN6
Study 31563959 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31563959 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 28537654 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28537654 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15082472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11360489 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29931216 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26285021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12843154 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12843154 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10993857 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10993857 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8869661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8869661 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 6860528 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27045864 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 22076422 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3927279 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 29394147 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 24323615 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24323615 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 20585108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12050273 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 10690807 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 27631388 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 27631388 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17664863 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 17664863 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 16105056 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 16105056 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 10199774 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12373416 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 10404500 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 10404500 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10404500 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 29738417 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29738417 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 23163117 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8803643 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1465278 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 25785316 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8706484 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30168415 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15051595 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15051595 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15051595 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29921143 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 27730819 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24478129 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 24478129 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24478129 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 29118060 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29118060 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29118060 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 26324220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30917364 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24433061 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16154305 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11873030 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7595856 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 2112480 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 28970080 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28970080 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24132975 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 19745163 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 19745163 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 19745163 — Biomarker: c-Jun N-terminal kinase
Type: Safety Biomarker (SAF)
Study 8435984 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 29083443 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25342738 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22959058 — Biomarker: HSPA1A mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA1A; HSP72; HSPA1; HSX70
Study 22959058 — Biomarker: PDIA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PDIA3; ERP57; ERP60; GRP58
Study 22959058 — Biomarker: PSME1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSME1; IFI5111
Study 22959058 — Biomarker: SMC6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMC6; SMC6L1
Study 22959058 — Biomarker: ECH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ECH1
Study 18226561 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7554761 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31743812 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 17630552 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9643054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28494751 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25143719 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 22421906 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12639061 — Biomarker: SRM mRNA
Type: Predictive Biomarker (PRD)
Genes: SRM; SPS1; SRML1
Study 2121359 — Biomarker: L-acetylcarnitine
Type: Safety Biomarker (SAF)
Study 26118476 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 26118476 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26118476 — Biomarker: SLPI mRNA
Type: Predictive Biomarker (PRD)
Genes: SLPI; WAP4; WFDC4
Study 15001599 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22257673 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22257673 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 16154442 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10895854 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 6541251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17632305 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 11400949 — Biomarker: CPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPB1; CPB; PCPB
Study 25536598 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23525426 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 30696812 — Biomarker: ADGRL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADGRL3; KIAA0768; LEC3; LPHN3
Study 10862538 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 8880362 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 1907056 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 12699137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24327037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25858265 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25858265 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23298304 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 9215249 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 7897254 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 19150019 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9862250 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26815944 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18853230 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1557595 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 1557595 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 31988233 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 31988233 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 31988233 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 31988233 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 26255814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23589163 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15837454 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12544411 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18781850 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 18781850 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 18781850 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16373648 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 14760042 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10958125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22660798 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18612266 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 1759005 — Biomarker: ARID3B mRNA
Type: Predictive Biomarker (PRD)
Genes: ARID3B; BDP; DRIL2
Study 25797743 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 25797743 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 29083258 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21960311 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 18519268 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26990694 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 24572452 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 24572452 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24572452 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24572452 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 22013959 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 17604562 — Biomarker: PAG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAG1; CBP; PAG
Study 15083437 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 8458802 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30714092 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 22588152 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 28051341 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21534640 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21534640 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18162322 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16340480 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 16340480 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16340480 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 16340480 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 20223872 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 18024537 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2571595 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 2571595 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2571595 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17503661 — Biomarker: CARTPT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CARTPT; CART
Study 28437029 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 26604214 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 12198060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31013275 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 23594362 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23594362 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11264734 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 2474100 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2474100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28729361 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 19820590 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19820590 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25408998 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14738659 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 25807399 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24338186 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21471106 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12653261 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 6327513 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27320538 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27320538 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27320538 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27320538 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24569538 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17608844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2158410 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2158410 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 17701883 — Biomarker: ATP7B mRNA
Type: Predictive Biomarker (PRD)
Genes: ATP7B; PWD; WC1; WND
Study 19320245 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16626956 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30835327 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 12826844 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 12826844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22339661 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 20150520 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7772916 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 21337541 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 21337541 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 21337541 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 21337541 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 21337541 — Biomarker: CD83 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD83
Study 22194590 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 19923521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9140209 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9140209 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 30738417 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31192555 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31192555 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10