AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 11336591 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 127471 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study 31658975 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 30357438 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28344144 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 23438932 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8000036 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 16291717 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 16291717 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 16291717 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 16291717 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 7650334 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 28459931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28459931 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28459931 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28459931 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21716078 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21716078 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18287793 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18287793 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 18287793 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 29284287 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 20806388 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 20806388 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11097197 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1392491 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1392491 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 1392491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3919522 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 22533654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22533654 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17851130 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 15818329 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 31159537 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 28602413 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28602413 — Biomarker: ESR1
Type: Predictive Biomarker (PRD)
Genes: NR3A1; Era; ER-alpha
Study 20827284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31356514 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24138325 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21388622 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21388622 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8612031 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29861827 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20339879 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15935231 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 12771001 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 10801996 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21310311 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7931881 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 2887430 — Biomarker: KCNN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNN1; SK
Study 23463093 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 22123359 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 22123359 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 1606596 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 27197280 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20456744 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 11225744 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11225744 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 31255574 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 10945489 — Biomarker: RNF135 mRNA
Type: Predictive Biomarker (PRD)
Genes: RNF135; L13
Study 3544622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22836602 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21493741 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12649925 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30072176 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 1747702 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25398660 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 25398660 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9185026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31626219 — Biomarker: SACS mRNA
Type: Predictive Biomarker (PRD)
Genes: SACS; KIAA0730
Study 8659732 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29985942 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29985942 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 29985942 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 29985942 — Biomarker: CCRL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCRL2; CCR11; CCR6; CKRX; CRAM; HCR
Study 12461302 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8761540 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 8761540 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8761540 — Biomarker: Serum phosphate
Type: Surrogate Endpoint (SUR)
Study 8761540 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27070534 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 10682151 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20608918 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 18087552 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15476904 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15476904 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25070447 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25070447 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 11587162 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11587162 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26069137 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26069137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28316072 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 28316072 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 22921855 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22921855 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22921855 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 3303402 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17785764 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 31801620 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24569263 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 24569263 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 16351563 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16351563 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 10467966 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 2120362 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30395687 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 26729347 — Biomarker: DSP mRNA
Type: Predictive Biomarker (PRD)
Genes: DSP
Study 20467151 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8723457 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 1401997 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 30266575 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30266575 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27051309 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 15824849 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31888744 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 26809984 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22372508 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17208587 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7656958 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7656958 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30919638 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 26241292 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9797188 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8634659 — Biomarker: SLC25A21 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A21; ODC
Study 2758537 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8484508 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 3437794 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 3437794 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23524841 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 19468757 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18317236 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 8156252 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22262647 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 22262647 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15930042 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12027069 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9500317 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7886650 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 23736733 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23736733 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11136171 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 3984837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30477827 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30477827 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30477827 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22870258 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10680840 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 10680840 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21127897 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 9357093 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 2751753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 999412 — Biomarker: CPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPZ
Study 25666724 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19170847 — Biomarker: ZFP36 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 24456217 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1