AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 18578967 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15914522 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15914522 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12872395 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 12872395 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 6330643 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6330643 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 15680454 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 31677701 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 22990651 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 11910298 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11910298 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8607111 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8607111 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 23859487 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 23859487 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7963412 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26006754 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 14995053 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31933278 — Biomarker: SLC40A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC40A1; FPN; FPN1; IREG1; SLC11A3; MSTP079
Study 31933278 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31933278 — Biomarker: SLC11A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC11A2; DCT1; DMT1; NRAMP2; OK/SW-cl.20
Study 25175757 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17070175 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17070175 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12603503 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 12556657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29725795 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 29725795 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 29725795 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 28629874 — Biomarker: C6orf15 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6orf15; STG; UNQ1840/PRO3566
Study 2441202 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21784377 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8397245 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2427042 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2427042 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22626879 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22626879 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 26895303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8778851 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 2212376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30739385 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21675889 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 19291356 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 12768070 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12768070 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11152056 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31102000 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 31102000 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 27334385 — Biomarker: FMR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMR1
Study 27334385 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20979935 — Biomarker: ELOVL6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELOVL6; FACE; LCE
Study 15961302 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 7786700 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28374645 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 31146613 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12215465 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12215465 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2175140 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2175140 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 2175140 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 2175140 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 25731923 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 15188172 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27934805 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18926145 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16095140 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 11034945 — Biomarker: ATP1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATP1A1
Study 11034945 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 11034945 — Biomarker: HSD3B1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HSD3B1; 3BH; HSDB3A
Study 11034945 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study 11034945 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10319782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8952866 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29666135 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29666135 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 29666135 — Biomarker: ROS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROS1; MCF3; ROS
Study 16282562 — Biomarker: TNFRSF1B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1B; TNFBR; TNFR2
Study 16282562 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16282562 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7832131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23644930 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19705288 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 3759224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3759224 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29020866 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 30923964 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 28462794 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 28462794 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 12957974 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11056759 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 26802916 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 10533795 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 31746962 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31746962 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23715024 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 22276820 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22276820 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22276820 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 22276820 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 2679036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1278069 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12451428 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 12451428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26696199 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 19302563 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19302563 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 3886708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15753902 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 9806261 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 359018 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26678511 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11157185 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11157185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8106965 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8044721 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8044721 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28333301 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28333301 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9635370 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 7791682 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2805603 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2805603 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 29369454 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 22858557 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30849721 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30849721 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30626863 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 30626863 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 15772568 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11958306 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 20051371 — Biomarker: SLC25A21 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A21; ODC
Study 9296896 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 8320928 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22276959 — Biomarker: DBI mRNA
Type: Predictive Biomarker (PRD)
Genes: DBI
Study 12575905 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12575905 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 19061694 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30748011 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28734759 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 10554734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9093645 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28888762 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28888762 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10639356 — Biomarker: NR4A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR4A3; CHN; CSMF; MINOR; NOR1; TEC
Study 30234853 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 24574902 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 18001879 — Biomarker: KDM5D mRNA
Type: Predictive Biomarker (PRD)
Genes: KDM5D; HY; HYA; JARID1D; KIAA0234; SMCY
Study 16708806 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10319783 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 30535218 — Biomarker: CLCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLCN1; CLC1
Study 30535218 — Biomarker: SCN4A mRNA
Type: Predictive Biomarker (PRD)
Genes: SCN4A
Study 15302800 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15302800 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15302800 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 11967252 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11967252 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11967252 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9718249 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 129494 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15233807 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15233807 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15233807 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 3300248 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16101362 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 12116341 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 12116341 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 12116341 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12116341 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 6377793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27470399 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27470399 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 23180520 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20492467 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 12427060 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 23761651 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23761651 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23761651 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23761651 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 20422422 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 10653205 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8843209 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8843209 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8843209 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 6711468 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31368267 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 8983866 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19719472 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 19719472 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26239595 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 26407878 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 25630513 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15723964 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31030363 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9073002 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7923728 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 3018603 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3018603 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17484080 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25287767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15878000 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11328289 — Biomarker: ETV6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV6; TEL; TEL1
Study 11328289 — Biomarker: RUNX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX1; AML1; CBFA2
Study 27658130 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24209423 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12519844 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 6140440 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19549615 — Biomarker: MAVS mRNA
Type: Predictive Biomarker (PRD)
Genes: MAVS; IPS1; KIAA1271; VISA
Study 19165197 — Biomarker: MLH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MLH1; COCA2
Study 19165197 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 16696522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24965494 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 23077137 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 18565950 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 6630409 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 24933232 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 21816443 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21816443 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25967705 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 21839455 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15053895 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15053895 — Biomarker: GAD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD2; GAD65
Study 9089564 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29644504 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25385173 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 25385173 — Biomarker: miR-31
Type: Predictive Biomarker (PRD)
Genes: MIR31
Study 25385173 — Biomarker: miR-181a
Type: Safety Biomarker (SAF)
Study 25385173 — Biomarker: miR-16
Type: Safety Biomarker (SAF)
Study 25385173 — Biomarker: miR-145
Type: Predictive Biomarker (PRD)
Genes: MIR145
Study 23523162 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 23523162 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 23523162 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 23523162 — Biomarker: CFHR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CFHR5; CFHL5; FHR5
Study 23523162 — Biomarker: F13B mRNA
Type: Predictive Biomarker (PRD)
Genes: F13B
Study 21701080 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21701080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19623684 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19623684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14639093 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9547443 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9547443 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 12891198 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 8911832 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)