AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT02530996 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT00358098 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study NCT00358098 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study NCT00358098 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00358098 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT04608422 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT03083223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02063763 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study NCT03068299 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT03428516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01819337 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT00779935 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00779935 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT04084951 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT05468294 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01158625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01567774 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT02048371 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT02108691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00491881 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00152061 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT01076673 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT00709878 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00709878 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT04382768 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT00123604 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00351325 — Biomarker: TNFRSF9 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF9; CD137; ILA
Study NCT02687516 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT02687516 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02687516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03764930 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study NCT01384032 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study NCT01384032 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00373945 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study NCT02442700 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT02442700 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01581203 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study NCT00944996 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT00944996 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT02965885 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02965885 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02965885 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT04437992 — Biomarker: LUM mRNA
Type: Predictive Biomarker (PRD)
Genes: LUM; LDC; SLRR2D
Study NCT02772926 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study NCT02772926 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT03013049 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT02283424 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00097890 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study NCT01798446 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT04638608 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study NCT03126799 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03126799 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03158935 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT03158935 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT01451281 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study NCT00185601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01756118 — Biomarker: PI3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PI3; WAP3; WFDC14
Study NCT01756118 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study NCT00687102 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT03864913 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study NCT01357317 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study NCT00130910 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04832945 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT01352520 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study NCT01648868 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study NCT03393507 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study NCT02653677 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT01447303 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT01554514 — Biomarker: ADAMTS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT00300365 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00641082 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT03255876 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT03169257 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study NCT03169257 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study NCT01875341 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00384865 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT03376698 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03376698 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT00043186 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00732121 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT00732121 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT00732121 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03176732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02358889 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT01850004 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT01850004 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT00082641 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study NCT01330823 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01306474 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT02314364 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02314364 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT02314364 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study NCT02314364 — Biomarker: ROS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROS1; MCF3; ROS
Study NCT02314364 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT02900170 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT02900170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04928729 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT05373732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02981966 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT00442325 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00466960 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00429078 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study NCT00508612 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00559130 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04070729 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT02830009 — Biomarker: PHC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PHC1; EDR1; PH1
Study NCT03174535 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04227223 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT03545126 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT00917462 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02176382 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02765464 — Biomarker: TIMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TIMP2
Study NCT02896270 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03106298 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT03168100 — Biomarker: SLAMF7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLAMF7; CS1; UNQ576/PRO1138
Study NCT02163798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02163798 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04527068 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT04527068 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT00822666 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT00936026 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study NCT01728155 — Biomarker: MYCN mRNA
Type: Predictive Biomarker (PRD)
Genes: MYCN; BHLHE37; NMYC
Study NCT02699905 — Biomarker: FFAR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FFAR2; FFA2; GPCR43; GPR43
Study NCT03042312 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03307031 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01860807 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04147936 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study NCT04267471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03544229 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study NCT03361098 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT01357161 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study NCT01357161 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study NCT01001962 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03231904 — Biomarker: LIF mRNA
Type: Predictive Biomarker (PRD)
Genes: LIF; HILDA
Study NCT01399268 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT06055660 — Biomarker: MSN mRNA
Type: Predictive Biomarker (PRD)
Genes: MSN
Study NCT02529657 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02529657 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT04642703 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT00030537 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT02568488 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT02568488 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study NCT04240236 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00827775 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02198261 — Biomarker: SULT1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SULT1A1; STP; STP1; OK/SW-cl.88
Study NCT03327168 — Biomarker: ADORA2A
Type: Safety Biomarker (SAF)
Genes: RDC8
Study NCT01465802 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01355913 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT02126072 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study NCT00722644 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00199888 — Biomarker: Carbonic anhydrase IX
Type: Predictive Biomarker (PRD)
Genes: CA9; G250; MN
Study NCT03754023 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study NCT03754023 — Biomarker: IGFBP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP7; MAC25; PSF
Study NCT03899116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03863782 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02910401 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study NCT03597282 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study NCT04208087 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study NCT02738775 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT01339533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00677547 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study NCT00677547 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT02502981 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT02774655 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02795286 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00976586 — Biomarker: IKBKG mRNA
Type: Predictive Biomarker (PRD)
Genes: IKBKG; FIP3; NEMO
Study NCT01123824 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT04068909 — Biomarker: SERPINA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA5; PCI; PLANH3; PROCI
Study NCT01954316 — Biomarker: PLK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLK4; SAK; STK18
Study NCT01980524 — Biomarker: MYCL mRNA
Type: Predictive Biomarker (PRD)
Genes: MYCL; BHLHE38; LMYC; MYCL1
Study NCT01980524 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT03964922 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03063541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03377335 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT01972789 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT01972789 — Biomarker: TRIM63 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study NCT01685021 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT06484361 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03398421 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT02412111 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study NCT00788164 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study NCT02782026 — Biomarker: BMPR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BMPR2; PPH1
Study NCT00103792 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study NCT03296696 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT02700230 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study NCT03411798 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03849768 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06382571 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study NCT06382571 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT03886597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01969071 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT02875002 — Biomarker: PLK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLK1; PLK
Study NCT04613609 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT04613609 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01577342 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT01734226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03787992 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04446741 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study NCT01730053 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00728858 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT00728858 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study NCT02136771 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study NCT00155168 — Biomarker: Survival motor neuron protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT01642394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02359721 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02359721 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study NCT02359721 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study NCT00451763 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02994030 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study NCT03415399 — Biomarker: DCLRE1C mRNA
Type: Predictive Biomarker (PRD)
Genes: DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C
Study NCT03415399 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT01864902 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study NCT02480673 — Biomarker: CHIA mRNA
Type: Predictive Biomarker (PRD)
Genes: CHIA
Study NCT01854190 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04524507 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT01353365 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT02354677 — Biomarker: SCGB1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SCGB1A1; CC10; CCSP; UGB
Study NCT02046434 — Biomarker: Synuclein alpha
Type: Pharmacodynamic Biomarker (PDY)
Genes: SNCA; NACP; PARK1
Study NCT01251796 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT01542866 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT01464528 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT02396394 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT05404516 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study NCT01545531 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study NCT01545531 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT00937976 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00937976 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT04410549 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT02297555 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01566578 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT01566578 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04034589 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04034589 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR