AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 17982923 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 12032413 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12032413 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 9241008 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 10369627 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 24622577 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24622577 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 27110446 — Biomarker: OXTR mRNA
Type: Predictive Biomarker (PRD)
Genes: OXTR
Study 14652120 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 14652120 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10646124 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10646124 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30815880 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 26681403 — Biomarker: GCLC mRNA
Type: Predictive Biomarker (PRD)
Genes: GCLC; GLCL; GLCLC
Study 26681403 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 26681403 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 26681403 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 26681403 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22968523 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18802155 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8450893 — Biomarker: AOX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AOX1; AO
Study 8450893 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 26271141 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17475459 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29858919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25297012 — Biomarker: SLC1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC1A2; EAAT2; GLT1
Study 10424315 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29747269 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31506369 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27776149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24964509 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 14557560 — Biomarker: VIM mRNA
Type: Predictive Biomarker (PRD)
Genes: VIM
Study 17519820 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 15369510 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7986469 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26205747 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26205747 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26205747 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26205747 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26205747 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21672969 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29281604 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 29281604 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17253883 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 17253883 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 15817726 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23462833 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23462833 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23462833 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21276586 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21276586 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21276586 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21276586 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 21276586 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 24084625 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8222677 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8222677 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30127051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18420877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17035872 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28982501 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23426978 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 11717214 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26769742 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30804065 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18591543 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15842212 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7640501 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18400704 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 14512000 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14512000 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14512000 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 31101682 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 31101682 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31101682 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7850234 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28287490 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 14633536 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 24710254 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24710254 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23474349 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study 10337871 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 10337871 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21816640 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 21640687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30053670 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 22137609 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 22137609 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 31782009 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31782009 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19814835 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19814835 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19814835 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 20329616 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7707626 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 19535188 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9549663 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3072894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17356554 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17356554 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16950182 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16950182 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21332611 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 10846911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26772171 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8293316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3191659 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18087660 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28681715 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 29035942 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7995005 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31714986 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31714986 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31714986 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25906818 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25906818 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21457576 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16688994 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 12955333 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12955333 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8931841 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22192151 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 22192151 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22192151 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 18035202 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 1974509 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1974509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29070709 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 29070709 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 26332304 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 19926054 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17143601 — Biomarker: Retinoblastoma-associated protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: RB1
Study 8058981 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16280028 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11987005 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31915152 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 17032876 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 11798687 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11798687 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11798687 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2086165 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19304472 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 19304472 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 11967245 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9527182 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 28744857 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28744857 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19736157 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 19736157 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 16802195 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21349928 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 21349928 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 19660021 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 11499564 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3365292 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17353577 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 17353577 — Biomarker: WWTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WWTR1; TAZ
Study 17568241 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17568241 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14597482 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11824893 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 8335426 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23980348 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23980348 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 23980348 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23980348 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23980348 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17045014 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17045014 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 1287557 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 18256460 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 27427132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15764256 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15764256 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15764256 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 2787289 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 31239644 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 31239644 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20031809 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22641256 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8778603 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 1405170 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 30595274 — Biomarker: CARTPT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CARTPT; CART
Study 30595274 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27618080 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27618080 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16082602 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10456206 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 8642805 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2144797 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2144797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7004678 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7004678 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 21047568 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9587121 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 7843867 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2015476 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28449402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26030788 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 17898401 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29718314 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29718314 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 29718314 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 28296582 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 15201943 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 11535498 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 26729437 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 24814037 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15660119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11986206 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 8083913 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 8738112 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27286693 — Biomarker: GARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GARS1; GARS
Study 31370809 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 26325514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23722111 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 15749490 — Biomarker: PCLAF mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 12131185 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12131185 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 29384243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28986814 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28098515 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26125572 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 15027183 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 9590187 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29636047 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27912986 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 17000226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8800590 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 22285555 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15807810 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 25583157 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25583157 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23941101 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21142609 — Biomarker: ZFP36 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 3945704 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 25864194 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25864194 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20090547 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18333870 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 11221289 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24261301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14557430 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2987636 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2987636 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1929022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6762195 — Biomarker: LUC7L3 mRNA
Type: Predictive Biomarker (PRD)
Genes: LUC7L3; CREAP1; CROP; O48