AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 25516371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17203292 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 15213052 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2686489 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2686489 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20519561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18075766 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 22443173 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 8955760 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8955760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25114912 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 25114912 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19478822 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 31833064 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21429214 — Biomarker: HDC mRNA
Type: Predictive Biomarker (PRD)
Genes: HDC
Study 21429214 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 2567113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2567113 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31148411 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 31148411 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26169561 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21352267 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 19701575 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9134282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 395959 — Biomarker: CARD16 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARD16; COP; COP1
Study 24950276 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21775749 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 21775749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21775749 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17091022 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15303639 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15303639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3305189 — Biomarker: VCP mRNA
Type: Predictive Biomarker (PRD)
Genes: VCP
Study 3305189 — Biomarker: SH2D2A mRNA
Type: Predictive Biomarker (PRD)
Genes: SH2D2A; SCAP; TSAD; VRAP
Study 12633783 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10686191 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 19363850 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8953207 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19228095 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15013031 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 7950223 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 28634365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18476292 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20382711 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18609485 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20841418 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20841418 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16606867 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16606867 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12568834 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 11342422 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 1721977 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2525329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28662448 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22610748 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19877104 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10624970 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1569602 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study 1569602 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1569602 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 1569602 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1569602 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 18580887 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16176119 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 16176119 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 28291552 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 25769303 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21497767 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 11192231 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22437088 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22437088 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18786316 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18786316 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18786316 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 6436633 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8590530 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26461465 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 15465451 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 11219471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16490581 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10769552 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 22715865 — Biomarker: ACAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAT1; ACAT; MAT
Study 20185746 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18705531 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12518369 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31175716 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 29215806 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 23127292 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 23127292 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25385719 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 25385719 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16685221 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18929283 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15879168 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 12410458 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 2646895 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29072162 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23462537 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 30221194 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 22472173 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 22472173 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7552929 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 28375035 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19717185 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 18003960 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 9557929 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9557929 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2656775 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31453723 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 19204207 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19204207 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 2677375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23676630 — Biomarker: AFM mRNA
Type: Predictive Biomarker (PRD)
Genes: AFM; ALB2; ALBA
Study 10847665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7475056 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7475056 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7475056 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29696643 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 7605757 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21178763 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16469151 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25997544 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 11522112 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11522112 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25885409 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 25885409 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24218874 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24218874 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15475831 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15475831 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 2150644 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11529630 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 9332682 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11717595 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31169350 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17225548 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9695642 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 24184996 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 19397392 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19397392 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 19397392 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19397392 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15304040 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 15304040 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 15304040 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15304040 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15304040 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 2696658 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 15978304 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15978304 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15978304 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10369648 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 1532551 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1532551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2984332 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22819432 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22819432 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7576933 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7576933 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30474700 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7821310 — Biomarker: L-acetylcarnitine
Type: Safety Biomarker (SAF)
Study 29098259 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1751665 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1751665 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 312708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27768857 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 27768857 — Biomarker: CYP2R1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2R1
Study 3175393 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30987269 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30987269 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 23283526 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31697384 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 17144438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10731530 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2410328 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 30531676 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26926681 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24621807 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22357725 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18473409 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18473409 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18473409 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 18473409 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 15723220 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 8782129 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27178983 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16253099 — Biomarker: LAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LAT
Study 24444353 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 29121401 — Biomarker: TRPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPA1; ANKTM1
Study 29121401 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 29231508 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20436711 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18486741 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 22370739 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17851565 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 17851565 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 15681300 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8895264 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 2049684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23651713 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25284808 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21518967 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12679925 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8992906 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2943685 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2943685 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 29133606 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29133606 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29133606 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22386831 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 20299258 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 23809982 — Biomarker: KCNN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNN1; SK
Study 8243427 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18606533 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10670117 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 22180344 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 20431612 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 17962233 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10516349 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29423410 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3922503 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16816766 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 25489410 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20508468 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 18569019 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18569019 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18569019 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 16055779 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30609212 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 18086944 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18086944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7795837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28235249 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21317198 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 17878421 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7653444 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7653444 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24641096 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15083372 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 7719523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7995674 — Biomarker: SMC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMC3; BAM; BMH; CSPG6; SMC3L1