AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 15690237 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 963960 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 30880937 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 28099408 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28099408 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 28099408 — Biomarker: APOA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOA5; RAP3; UNQ411/PRO773
Study 28099408 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15570142 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 26224300 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20807467 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31666831 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 17944274 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 15081561 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27002107 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 27002107 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 27002107 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27002107 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 25394434 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 25394434 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 25394434 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 25394434 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 20412149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17058828 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 24873996 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24873996 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19684633 — Biomarker: HDC mRNA
Type: Predictive Biomarker (PRD)
Genes: HDC
Study 12689974 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8906513 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8906513 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30665829 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30544421 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 27502582 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18199500 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28692301 — Biomarker: CYP27B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 28692301 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 10626290 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 15767215 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15767215 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10223772 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 10223772 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 10223772 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 27829181 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21442803 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24637537 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 22240264 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 1860093 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29389742 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26426999 — Biomarker: HGD mRNA
Type: Predictive Biomarker (PRD)
Genes: HGD; HGO
Study 2056908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30084414 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30084414 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 28480270 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 28480270 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 28480270 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17531459 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17531459 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17531459 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17531459 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16600640 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 26277090 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3907323 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22573119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18628657 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12663296 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 12663296 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31685792 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31685792 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31685792 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20051370 — Biomarker: Protein patched homolog 1
Type: Predictive Biomarker (PRD)
Genes: PTCH1; PTCH
Study 20051370 — Biomarker: PTGS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGS1; COX1
Study 20051370 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 18624836 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 12379291 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 10909468 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10909468 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10909468 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 10909468 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 2149514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7030578 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25904073 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15106797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2318222 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31550363 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 29228822 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23943825 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23943825 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 23943825 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19052855 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19052855 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10826401 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10826401 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10826401 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 6397541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25031274 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22414522 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 10671818 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 10671818 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6650766 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 26762988 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26762988 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17006376 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10789186 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 30165479 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 25038486 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 24620920 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 28659138 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 27800649 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 27800649 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 19531212 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11668308 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 7877519 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27846824 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 23460707 — Biomarker: GLI2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLI2; THP
Study 20529344 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 20529344 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 20529344 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 18971890 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7966600 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 29187694 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 29187694 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27638812 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16890481 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 27287210 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 2028627 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28675660 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 26393645 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 10669372 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 8229139 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 8889352 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16371185 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8555805 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26910781 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26910781 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7526027 — Biomarker: HRG mRNA
Type: Predictive Biomarker (PRD)
Genes: HRG
Study 7526027 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7526027 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 7526027 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 19011227 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19011227 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28542805 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 17010541 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7828258 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31883728 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 31883728 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17357764 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20608874 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 16467544 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 11273139 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9359537 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29865227 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29865227 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24836866 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 24836866 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15797313 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1453598 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 1453598 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27143684 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22703382 — Biomarker: ADRB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB1; ADRB1R; B1AR
Study 20006592 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 11237351 — Biomarker: MATN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MATN1; CMP; CRTM
Study 8297216 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11198483 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30530801 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 26367064 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 1534646 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17386350 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16623036 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28923084 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 28923084 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 10984013 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 9001327 — Biomarker: KCNN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNN1; SK
Study 8105943 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8105943 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 31504110 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24448010 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19236785 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study 12492609 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 785608 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26214684 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23687089 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 23687089 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 23687089 — Biomarker: IDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH2
Study 23687089 — Biomarker: DNMT3A mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMT3A
Study 23687089 — Biomarker: CDKN2A mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2A; CDKN2; MTS1
Study 23687089 — Biomarker: CDKN2B mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2B; MTS2
Study 23687089 — Biomarker: NOTCH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOTCH1; TAN1
Study 23687089 — Biomarker: BCL11B mRNA
Type: Predictive Biomarker (PRD)
Genes: BCL11B; CTIP2; RIT1
Study 17370665 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 17370665 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 15220300 — Biomarker: BAD mRNA
Type: Predictive Biomarker (PRD)
Genes: BAD; BBC6; BCL2L8
Study 2116057 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 28004188 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22018631 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19886855 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15378542 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 30400586 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 30400586 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22301466 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 10051277 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 6966082 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 27488051 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 11817529 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 11817529 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 20571015 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17324600 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17324600 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17324600 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 17324600 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17324600 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 11893367 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8495830 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8495830 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8495830 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 2468875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24305424 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21429720 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21429720 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21429720 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21429720 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 28541646 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 28254462 — Biomarker: Fatty acid amide hydrolase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: FAAH; FAAH1
Study 21547897 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 14602435 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 1434725 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 24665980 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 22462425 — Biomarker: BAD mRNA
Type: Predictive Biomarker (PRD)
Genes: BAD; BBC6; BCL2L8
Study 22462425 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23547849 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23547849 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10191213 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10191213 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 7762255 — Biomarker: CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR1; C3BR
Study 7762255 — Biomarker: CR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR2; C3DR
Study 28000034 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9517646 — Biomarker: LAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LAT
Study 7922791 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1940775 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 18180889 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 18180889 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11486790 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8252746 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 3545477 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3545477 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 20308250 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 20308250 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 20308250 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 18400273 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 15807179 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15807179 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24615745 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19