AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 29142982 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9358138 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28190787 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 28190787 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 19538718 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 16951642 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20627015 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 27565734 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1713269 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1713269 — Biomarker: Coagulation factor Va
Type: Safety Biomarker (SAF)
Genes: F5
Study 1713269 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 1713269 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17272969 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 402569 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31265450 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11304662 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7948814 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 3063488 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23596158 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23596158 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 18199149 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 16775595 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16775595 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1449044 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 29413685 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 29413685 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29413685 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 29413685 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 17487649 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17487649 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7033014 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31289019 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 30447975 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31399442 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 19214552 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 8020690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19167684 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 8254181 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30063180 — Biomarker: ADRA2A mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRA2A; ADRA2R; ADRAR
Study 30063180 — Biomarker: ELK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELK3; NET; SAP2
Study 23849811 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 6385893 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30756302 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 29654805 — Biomarker: INTU mRNA
Type: Predictive Biomarker (PRD)
Genes: INTU; KIAA1284; PDZD6; PDZK6
Study 29654805 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 8704351 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30698675 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 27930553 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 24785399 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 19361146 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22833684 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22833684 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 26840438 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 8558194 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 28833192 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 28833192 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28833192 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 18926645 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17698275 — Biomarker: SPIN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPIN1; OCR; SPIN
Study 17698275 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 23376362 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12815565 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31902378 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31902378 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30998063 — Biomarker: HFE mRNA
Type: Predictive Biomarker (PRD)
Genes: HFE; HLAH
Study 26000667 — Biomarker: SERPINA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA2; ARGS; ATR; PIL; SERPINA2P
Study 8001628 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 14621746 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 26118825 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23865389 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21717822 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21717822 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21717822 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21717822 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20479668 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9756248 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7804510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22639013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19224430 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study 11602545 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11602545 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7614520 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7614520 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2146369 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 28332191 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24142853 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1764956 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30943275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22438298 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25074318 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 25074318 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 25074318 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 8098220 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8098220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31568587 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 31568587 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31568587 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 31568587 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 28551073 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26228487 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 18652688 — Biomarker: GK mRNA
Type: Predictive Biomarker (PRD)
Genes: GK
Study 11921591 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11921591 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31651545 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 410176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30776911 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23480523 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21665007 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21665007 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21665007 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11336159 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 3655855 — Biomarker: MERTK mRNA
Type: Predictive Biomarker (PRD)
Genes: MERTK; MER
Study 3655855 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 31987106 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27102821 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 24441153 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24441153 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18474338 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18474338 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 350500 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11195315 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20103724 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 16140708 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16140708 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16140708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30990099 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 8933551 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 30712751 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28225475 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 28225475 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 28225475 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28225475 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 28225475 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19476473 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 11641371 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 9734766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24006749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21106985 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 18356327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16214598 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 10408591 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10408591 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30586698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21294929 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 21294929 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19696440 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17355733 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 3072180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30803434 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 20189611 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20189611 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12818245 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18001269 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27575011 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 27575011 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9683397 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 29128507 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 24560157 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 20664891 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11869839 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22707271 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 22707271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12783370 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 12783370 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 12783370 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 10893682 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 19765066 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3056431 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 31780418 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 25986590 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 17823446 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15114779 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 31722135 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 23908125 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19552744 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 11456368 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 27443525 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17083726 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 15617307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24567316 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23731980 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20629545 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 12959938 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10664525 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 30408722 — Biomarker: NR3C1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR3C1; GRL
Study 14556808 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 3768764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18677171 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12612947 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 12612947 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12612947 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12612947 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10491228 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26864124 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26864124 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21849640 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 24019415 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 19487264 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12617709 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 9105988 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 3770017 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29531173 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23733907 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 22640372 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21357180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19641488 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 19641488 — Biomarker: NTRK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NTRK2; TRKB
Study 19641488 — Biomarker: ADRA2A mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRA2A; ADRA2R; ADRAR
Study 19641488 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 28774794 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 26477692 — Biomarker: IL1RN mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RN; IL1F3; IL1RA
Study 26477692 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26477692 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 19705205 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17189962 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 17189962 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 15371578 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9842823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8080740 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 31675420 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 31675420 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 31675420 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31675420 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31675420 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 27755057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23800977 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18353314 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18353314 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 27956407 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2898027 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2898027 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21298859 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7957544 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31909431 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15131558 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9310811 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9310811 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23701262 — Biomarker: HCAR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: HCAR2; GPR109A; HCA2; HM74A; NIACR1
Study 23701262 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 19926370 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25945079 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 25945079 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11434941 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9887454 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18405061 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 10997957 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 8792252 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)