AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 19710199 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15115249 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15115249 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 27127117 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 12871461 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 25455039 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25455039 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10673249 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28719717 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 28719717 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 3046815 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3046815 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 27492015 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 25475357 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 14662281 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31422507 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study 30343028 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 30343028 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20799043 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 20799043 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 20799043 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 18830816 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27211272 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 27211272 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 17514537 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17514537 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10052485 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10052485 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16053664 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16053664 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22046862 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2390921 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 2390921 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 25598270 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 15046934 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 7927488 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 19552598 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 19552598 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19552598 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17349072 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24990422 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2243148 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29667330 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25787780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22401327 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18729835 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15856409 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 15856409 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 15856409 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 15856409 — Biomarker: NR1I2
Type: Predictive Biomarker (PRD)
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 14585254 — Biomarker: CLN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLN3; BTS
Study 8112371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24053794 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 22464673 — Biomarker: FSCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FSCN1; FAN1; HSN; SNL
Study 22464673 — Biomarker: IRF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRF4; MUM1
Study 22464673 — Biomarker: NMES1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NMES1; C15orf48
Study 22464673 — Biomarker: MX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MX1
Study 22464673 — Biomarker: TRAF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRAF1; EBI6
Study 22464673 — Biomarker: Phospholipase A2 inhibitory protein
Type: Predictive Biomarker (PRD)
Genes: ANXA1; ANX1; LPC1
Study 22464673 — Biomarker: TSC22D3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSC22D3; DSIPI; GILZ
Study 22464673 — Biomarker: F13A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: F13A1; F13A
Study 22464673 — Biomarker: FKBP5 mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: FKBP5; AIG6; FKBP51
Study 22464673 — Biomarker: STAB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAB1; FEEL1; KIAA0246
Study 20973922 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 18242584 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15058795 — Biomarker: SMARCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMARCA2; BAF190B; BRM; SNF2A; SNF2L2
Study 29529897 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29529897 — Biomarker: T-cell specific protein RANTES
Type: Safety Biomarker (SAF)
Genes: CCL5; D17S136E; SCYA5
Study 24940825 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19850944 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 7845026 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24521775 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19506333 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 9627948 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 8185271 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 28012910 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28012910 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11127459 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 1396832 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17768460 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15080014 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23034957 — Biomarker: TCF7L2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCF7L2; TCF4
Study 20550022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1094320 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27399127 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 27399127 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27399127 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 707580 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 19183161 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19183161 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9732070 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9732070 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 22621316 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22621316 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17603846 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 17603846 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 17603846 — Biomarker: CCR9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR9; GPR28
Study 11524061 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8596135 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 28503774 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 28503774 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28370407 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22290681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11316108 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28992127 — Biomarker: PRKD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKD1; PKD; PKD1; PRKCM
Study 28992127 — Biomarker: PKD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PKD2; TRPP2
Study 28992127 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 21393063 — Biomarker: Peripheral myelin protein 22
Type: Pharmacodynamic Biomarker (PDY)
Genes: PMP22; GAS3
Study 7171533 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28010246 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 17827369 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29807936 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26720473 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 21509050 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12818462 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 12818462 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8769685 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24536039 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24536039 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18197497 — Biomarker: AQP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP3
Study 18197497 — Biomarker: AQP9 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP9; SSC1
Study 12630074 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30699971 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30699971 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 23551992 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23551992 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23551992 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 21342323 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21342323 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 28232237 — Biomarker: NE
Type: Predictive Biomarker (PRD)
Study 21878470 — Biomarker: DISC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DISC1; KIAA0457
Study 7744190 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2286480 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23113482 — Biomarker: New morphometric vertebral fractures
Type: Surrogate Endpoint (SUR)
Study 23113482 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20166859 — Biomarker: ZFP36 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 8703663 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19954718 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19954718 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 17300851 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 11316974 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 9396403 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20428722 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12551868 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1676617 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 27321385 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 28719765 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24279607 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 23095869 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19235040 — Biomarker: CCND2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND2
Study 19235040 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 2146870 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11588535 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9681776 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16940981 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10569685 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21960073 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12771613 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12771613 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10688831 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 10688831 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29905646 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 21084620 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 16355622 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 16355622 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11279324 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18843927 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 16137437 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 10915232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27974950 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20194883 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11896513 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 7860418 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 913294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6782605 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 27336726 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 27336726 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27336726 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27336726 — Biomarker: CDK6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK6; CDKN6
Study 27336726 — Biomarker: CCND2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND2
Study 27336726 — Biomarker: CCND3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND3
Study 27336726 — Biomarker: CCNE1 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCNE1; CCNE
Study 27336726 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 27336726 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 20417445 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22197676 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 22197676 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 8596594 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24928217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20586550 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 19014790 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 12023993 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 12023993 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 1838079 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1838079 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 1838079 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1838079 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23637556 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16678551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11295031 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24458199 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21435695 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 21435695 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16814206 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 23082801 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 19246893 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 14691439 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11720197 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2577461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19666939 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 11288049 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8307554 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 3709026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31713941 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31713941 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20367777 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 11950104 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 760698 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21893621 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21893621 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21893621 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8435262 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 8435262 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 8435262 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study 27756037 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27756037 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24142329 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 16868539 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30535651 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9562008 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9562008 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25586095 — Biomarker: HMGA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HMGA1; HMGIY
Study 22476908 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 16518702 — Biomarker: MT2A mRNA
Type: Predictive Biomarker (PRD)
Genes: MT2A; CES1; MT2
Study 10413279 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 10413279 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8689462 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 698165 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21191143 — Biomarker: ABL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABL2; ABLL; ARG
Study 21191143 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 15235055 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 14564675 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14564675 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)