AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 28241420 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25788034 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 19903804 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 28338531 — Biomarker: PCLO mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLO; ACZ; KIAA0559
Study 27353769 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19861864 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 11207993 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 25526373 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25526373 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23289919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17137514 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10872704 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23277436 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 19042325 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 2878131 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 2878131 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 26774608 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26774608 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20152247 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20152247 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11384090 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 3305118 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 21209232 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 21209232 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 23043721 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 22156381 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 22156381 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29139142 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 20620495 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 23853000 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 20079691 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20079691 — Biomarker: TOP2A mRNA
Type: Predictive Biomarker (PRD)
Genes: TOP2A; TOP2
Study 15164106 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29444672 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 27130844 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 27130844 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27130844 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 27130844 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 27130844 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 20685303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14971151 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22274319 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 10472562 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 23887713 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 20886801 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 11882622 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30504059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24393750 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19351725 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19351725 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17584312 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 8458362 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21212710 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 21212710 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 15071277 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11789241 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 9110906 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20943046 — Biomarker: CCRL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCRL2; CCR11; CCR6; CKRX; CRAM; HCR
Study 20943046 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14616416 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 14616416 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 14616416 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 8157385 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29274617 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29274617 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 28179349 — Biomarker: GPX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPX1
Study 11524040 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22867539 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 18809631 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 10752988 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 8783785 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8783785 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 1291700 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 29558323 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29558323 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30061156 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24806747 — Biomarker: DGAT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DGAT2; HMFN1045; UNQ738/PRO1433
Study 22907079 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22907079 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17704866 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12768736 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 6366151 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27128667 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20467874 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 20467874 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 29031778 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29031778 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 26156156 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 27039236 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20106824 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20106824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17394248 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 19416224 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19416224 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15693087 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15693087 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15693087 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 7665720 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 25494871 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 25494871 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 15181066 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 2144260 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11709782 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 11709782 — Biomarker: CCR2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCR2; CMKBR2
Study 11709782 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11709782 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 1643938 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 26933897 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26933897 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 17365993 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 7906288 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23331518 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 17719763 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11350501 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 11350501 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 22038464 — Biomarker: PPARGC1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARGC1B; PERC; PGC1; PGC1B; PPARGC1
Study 11897207 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9471927 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2369475 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 25623393 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25623393 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2215615 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2215615 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24429536 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22664560 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 30585832 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30585832 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30585832 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 30585832 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 28330649 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26491284 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22045675 — Biomarker: miR-122
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR122
Study 22045675 — Biomarker: miR-192
Type: Safety Biomarker (SAF)
Genes: MIR192
Study 8172088 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2963793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23897243 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 23897243 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 20220045 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 2192406 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 96459 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 19917869 — Biomarker: CD3D mRNA
Type: Predictive Biomarker (PRD)
Genes: CD3D; T3D
Study 19917869 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 2198635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31155415 — Biomarker: IVNS1ABP mRNA
Type: Predictive Biomarker (PRD)
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068
Study 23642856 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23642856 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17223996 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 30557099 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 17708864 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9439556 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27062851 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24739260 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3084015 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29351885 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 9042663 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 9042663 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22230474 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20124517 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 1319523 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27006189 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25269900 — Biomarker: AZIN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AZIN2; ADC; KIAA1945; ODCP
Study 17933438 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16277797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16277797 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7767538 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 26805529 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 26805529 — Biomarker: Lung surfactant protein D
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: SFTPD; COLEC7; PSPD; SFTP4
Study 21880336 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14998944 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16495245 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 8444719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3097726 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30242809 — Biomarker: NPSR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NPSR1; GPR154; GPRA; PGR14
Study 26810768 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 22775412 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18779512 — Biomarker: CACNA1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CACNA1A; CACH4; CACN3; CACNL1A4
Study 18779512 — Biomarker: ATP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATP1A2; KIAA0778
Study 8722429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30209126 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 30209126 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15167303 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21304095 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7930717 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 7930717 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24846511 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19501210 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16584059 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 14667178 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 8618436 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24793176 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 22537767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20666584 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 17346816 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 7963710 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7963710 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 23584130 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23584130 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16924028 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 26976420 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22921891 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22921891 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 22921891 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22921891 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17585311 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 24317968 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30325658 — Biomarker: CIDEC mRNA
Type: Predictive Biomarker (PRD)
Genes: CIDEC; FSP27
Study 15654716 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 26142578 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 31927748 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31927748 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31927748 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16197666 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6999291 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6999291 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23642941 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22729015 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 12460706 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8842510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1345755 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31115592 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16491208 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11551003 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 3129362 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 3129362 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 25262675 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 21499725 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 24962851 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11524323 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25966929 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 25966929 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24072967 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24072967 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11720830 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27564555 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 23154578 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 23154578 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 23154578 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23154578 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23154578 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 23154578 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19493418 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)