AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23450056 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8865916 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20697948 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 20697948 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18606250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11886178 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10452749 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 7256979 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17174527 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 16680285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11478142 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 8859724 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8859724 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31961420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27136744 — Biomarker: ROS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROS1; MCF3; ROS
Study 27136744 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 27136744 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 27136744 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17685853 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 17685853 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 21760549 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16775552 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 11524344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3423310 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3423310 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28372335 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 18480688 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 11094013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1893647 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1893647 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20664489 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 20664489 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 17172427 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 11081318 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30908367 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 30396975 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9076381 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 9076381 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18098228 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18098228 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 16579997 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 16579997 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 12690917 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12690917 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 12690917 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12690917 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11135795 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20813866 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 23878167 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22076596 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15721999 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 16285179 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 29432379 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18489783 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 10996579 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 20424140 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 20424140 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8580688 — Biomarker: ALPK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALPK1; KIAA1527; LAK
Study 8580688 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 21998259 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 21998259 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 20480225 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18705755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18705755 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7468946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6342641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16326298 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 27888608 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23419231 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28003203 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24047919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24047919 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24047919 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18205185 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18205185 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16443229 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 16443229 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 16443229 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16443229 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 8630663 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 22624697 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20722555 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18408611 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18408611 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 18408611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23569138 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23569138 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22173365 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22173365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14732723 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11712625 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 31064847 — Biomarker: SPN mRNA
Type: Predictive Biomarker (PRD)
Genes: SPN; CD43
Study 29409143 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 29409143 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 25002832 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8683249 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30883050 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15172423 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 15172423 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15172423 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 20881001 — Biomarker: TPBG mRNA
Type: Predictive Biomarker (PRD)
Genes: TPBG; 5T4
Study 20881001 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30608390 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27296705 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24810181 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24810181 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10654204 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1858733 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 1858733 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 1858733 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 1858733 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 29178024 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 8698440 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8698440 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31707982 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29411495 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26822582 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26822582 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 26822582 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22301929 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9569128 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study 9569128 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 28720715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19832818 — Biomarker: LNX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LNX1; LNX; PDZRN2; UNQ574/PRO1136
Study 2692332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2692332 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 28446804 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28446804 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 30954969 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20079220 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 14982911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8285181 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24553426 — Biomarker: ADH1B mRNA
Type: Predictive Biomarker (PRD)
Genes: ADH1B; ADH2
Study 17706223 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 10585065 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 22781792 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 20193551 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20193551 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11593916 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18801781 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17081623 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17081623 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17081623 — Biomarker: CCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR4; CMKBR4
Study 14996484 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14996484 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9489643 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19935778 — Biomarker: KRT6A mRNA
Type: Predictive Biomarker (PRD)
Genes: KRT6A; K6A; KRT6D
Study 17397308 — Biomarker: STUB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STUB1; CHIP; PP1131
Study 7486603 — Biomarker: SLC10A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC10A3; DXS253E; P3
Study 30302786 — Biomarker: Survival motor neuron protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 24495792 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24495792 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24495792 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24495792 — Biomarker: FOXP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 17927554 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17927554 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16371925 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 16371925 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23981400 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 21856226 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 21856226 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 9719164 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9719164 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9719164 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 2673623 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1273208 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 31354513 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29020329 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20513595 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20513595 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18062901 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 7614911 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 24549371 — Biomarker: FGFR1
Type: Predictive Biomarker (PRD)
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 16336830 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 16336830 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 11673584 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 7948796 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 3358596 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28017787 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 18936474 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18936474 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 16476120 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12897047 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10650326 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29080119 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24619763 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20707886 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 7813254 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 30286855 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 19713152 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 12032117 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9836078 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2591258 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 1098888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21606192 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21606192 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 21606192 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 21606192 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16948972 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 16948972 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16948972 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9435196 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9435196 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 21730216 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21730216 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 17341994 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22308289 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 18693743 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 25567682 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25567682 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20570237 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16009446 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16009446 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12492585 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 21717516 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21717516 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21717516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17544845 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 17544845 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10553915 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18205096 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18205096 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 28724309 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9570426 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25633584 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 16531797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1412113 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24758075 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18953863 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12149106 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 12149106 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7721636 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 29117336 — Biomarker: TUBB2A mRNA
Type: Predictive Biomarker (PRD)
Genes: TUBB2A; TUBB2
Study 29117336 — Biomarker: CEP72 mRNA
Type: Predictive Biomarker (PRD)
Genes: CEP72; KIAA1519
Study 29117336 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 29117336 — Biomarker: GSK3B mRNA
Type: Predictive Biomarker (PRD)
Genes: GSK3B