AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 11783153 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 7825526 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 396673 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30146268 — Biomarker: LUM mRNA
Type: Predictive Biomarker (PRD)
Genes: LUM; LDC; SLRR2D
Study 21953763 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 18187214 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 18187214 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15845678 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12692006 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 6759144 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24611484 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24611484 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24611484 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 17239062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9585772 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2172376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 629073 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30548890 — Biomarker: DSE mRNA
Type: Predictive Biomarker (PRD)
Genes: DSE; SART2
Study 28541285 — Biomarker: PAG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAG1; CBP; PAG
Study 21113789 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21113789 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 21113789 — Biomarker: SEMG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEMG1; SEMG
Study 16772250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3038254 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18487911 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 10321445 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2691818 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21062392 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 31364232 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31556273 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 25769495 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31987331 — Biomarker: GDF9 mRNA
Type: Predictive Biomarker (PRD)
Genes: GDF9
Study 31987331 — Biomarker: PDSS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PDSS2; C6orf210; DLP1
Study 17911541 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 8046120 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26969308 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 22739369 — Biomarker: ALOX5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALOX5; LOG5
Study 22739369 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10670114 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 24698485 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11739089 — Biomarker: AWAT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AWAT2; DC4; DGAT2L4; MFAT; WS
Study 2285609 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 30280324 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 18347178 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 18347178 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19918017 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 17092654 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 31851082 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 24898857 — Biomarker: ATAD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATAD2; L16; PRO2000
Study 14720530 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 14720530 — Biomarker: GAPDH mRNA
Type: Predictive Biomarker (PRD)
Genes: GAPDH; GAPD; CDABP0047; OK/SW-cl.12
Study 8206564 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8150546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27413042 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27413042 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12814444 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2058867 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2058867 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 25596881 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 25596881 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 23980876 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21378141 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6185089 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 31705750 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24869931 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15329918 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 11060829 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 26458258 — Biomarker: ADH1B mRNA
Type: Predictive Biomarker (PRD)
Genes: ADH1B; ADH2
Study 26458258 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26458258 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18853428 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15240647 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3130925 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22852760 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22852760 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 9440748 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 9440748 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2684073 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15242424 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 1655350 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31529492 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 27921413 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 16574438 — Biomarker: GYPC mRNA
Type: Predictive Biomarker (PRD)
Genes: GYPC; GLPC; GPC
Study 1359211 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31550290 — Biomarker: FMR1
Type: Predictive Biomarker (PRD)
Genes: FMRP; FRAXA; MGC87458
Study 27624603 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 27624603 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 7795830 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 359140 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11204665 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 11204665 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 8318783 — Biomarker: TIMM8A mRNA
Type: Predictive Biomarker (PRD)
Genes: TIMM8A; DDP; DDP1; TIM8A
Study 8318783 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 25062396 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18799820 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18799820 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18799820 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18799820 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 18799820 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10480471 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10480471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28728281 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6871776 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6871776 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 21909730 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9793810 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11527130 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11527130 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 11527130 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 11527130 — Biomarker: PRCP mRNA
Type: Predictive Biomarker (PRD)
Genes: PRCP; PCP
Study 11527130 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27676149 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31669625 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 31669625 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 22463757 — Biomarker: TRIL mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIL; KIAA0644
Study 19119028 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19119028 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9671379 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 12764908 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 7586434 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 17005527 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17005527 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 17005527 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 2956957 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 25365133 — Biomarker: HHIP mRNA
Type: Predictive Biomarker (PRD)
Genes: HHIP; HIP; UNQ5825/PRO19644
Study 20147570 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 20147570 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 17126653 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17126653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23428009 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 30782687 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10480514 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 2187384 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 29882203 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29882203 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29882203 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 29882203 — Biomarker: VCAM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VCAM1
Study 29882203 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16533939 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16533939 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10840011 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10840011 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1614253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30833130 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22773591 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17919105 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 17919105 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17919105 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 28385131 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25172378 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 17908370 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 30916463 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 7525446 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 7525446 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 29861487 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15782425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12404882 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12404882 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7582380 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 2348453 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29184389 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 24592747 — Biomarker: TERF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TERF1; PIN2; TRBF1; TRF; TRF1
Study 14962945 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9856369 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9856369 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 20168213 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 20168213 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 15590711 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12085418 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30076458 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30076458 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19020851 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 10856317 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 10856317 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 9104901 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25286691 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 10652037 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10652037 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 10652037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10652037 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 28237635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19680681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9447478 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 29788487 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29788487 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 28902705 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25411292 — Biomarker: PRKN mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKN; PARK2
Study 25411292 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25411292 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 16806873 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16806873 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12040528 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7719244 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 29349976 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25440999 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19496776 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10856892 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 3510282 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 3510282 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23102995 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23102995 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20634749 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20634749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18607829 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28389389 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 28389389 — Biomarker: TRPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPA1; ANKTM1
Study 28389389 — Biomarker: TRPV4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV4; VRL2; VROAC
Study 28389389 — Biomarker: TRPM8 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPM8; LTRPC6; TRPP8
Study 28389389 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 15503074 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 11416677 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29696963 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29696963 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29696963 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26796240 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23365129 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 27445627 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24670520 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23457387 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 23457387 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 23457387 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 23457387 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21930598 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study 21930598 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 21930598 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 21930598 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21930598 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15173128 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12117291 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12117291 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 25477424 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19517675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16997310 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16997310 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16997310 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 16997310 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 16997310 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 26523993 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16180033 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 16303728 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16303728 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2131793 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 773486 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2239886 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 20737243 — Biomarker: MT2A mRNA
Type: Predictive Biomarker (PRD)
Genes: MT2A; CES1; MT2
Study 20737243 — Biomarker: TFRC mRNA
Type: Predictive Biomarker (PRD)
Genes: TFRC
Study 11710825 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7964949 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP