AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 25029703 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24130351 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9989311 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 25994179 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20598444 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20598444 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 12720590 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9076452 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 8439828 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10341672 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 23014489 — Biomarker: LAT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAT2; LAB; NTAL; WBS15; WBSCR15; WBSCR5; HSPC046
Study 23014489 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17678776 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17678776 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22342916 — Biomarker: TLR9
Type: Predictive Biomarker (PRD)
Genes: CD289
Study 7848930 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 3907037 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 10220011 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 23273538 — Biomarker: Chromosome 5q
Type: Predictive Biomarker (PRD)
Study 8204940 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8204940 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23642372 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19451297 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10924375 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 3907288 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 30256758 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 17156651 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17156651 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17156651 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31407856 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 31407856 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11589384 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 31084259 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9277416 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 3179922 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 1163469 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25793988 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 23706051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19632695 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 14686965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14686965 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23866979 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 16952987 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16952987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16952987 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11275039 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 25304725 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3046385 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 28939589 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25386711 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2494397 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 56146 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 23065659 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 23065659 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8160720 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8160720 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31892263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18471512 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25640037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12196659 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10503860 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24980290 — Biomarker: CYBB mRNA
Type: Predictive Biomarker (PRD)
Genes: CYBB; NOX2
Study 7766324 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9613379 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 326034 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27906839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26041745 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26041745 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26041745 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 16113459 — Biomarker: CRHR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CRHR1; CRFR; CRFR1; CRHR
Study 29324705 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29324705 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 14685749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8028506 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 8028506 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8028506 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21637908 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 11824325 — Biomarker: ZFP36 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 7818058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15915010 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12409652 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 31769533 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28117400 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 28117400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23702253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23702253 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 17953695 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17953695 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24565698 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 12243291 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10328327 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1963183 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12628531 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7682427 — Biomarker: EMB mRNA
Type: Predictive Biomarker (PRD)
Genes: EMB
Study 7682427 — Biomarker: HLA-DMB mRNA
Type: Predictive Biomarker (PRD)
Genes: HLA-DMB; DMB; RING7
Study 27096580 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15630410 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 15630410 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 6637574 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31146326 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19528843 — Biomarker: NINL mRNA
Type: Predictive Biomarker (PRD)
Genes: NINL; KIAA0980; NLP
Study 15600245 — Biomarker: STT3A mRNA
Type: Predictive Biomarker (PRD)
Genes: STT3A; ITM1; TMC
Study 9498972 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9498972 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 31522376 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 22863660 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 9626637 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 9626637 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31954199 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 30659702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25559659 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 15133849 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15133849 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11481387 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9504446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19633475 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 16752169 — Biomarker: APOA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOA5; RAP3; UNQ411/PRO773
Study 16752169 — Biomarker: APOC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOC3
Study 16752169 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 11942734 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 26853341 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26853341 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 18563435 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11872916 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10510145 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11352373 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9671370 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 31578168 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23640486 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22093195 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19236773 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 19236773 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 19236773 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 19236773 — Biomarker: CD7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD7
Study 23663658 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 23663658 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 17346425 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17346425 — Biomarker: CXCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR1; CMKAR1; IL8RA
Study 17346425 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 17346425 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24151693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14551493 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 31182401 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29242283 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 25022113 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 17400142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16264158 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 376950 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 19563586 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 10698386 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 10698386 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23356032 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15593392 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 17122083 — Biomarker: IGF1R mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1R
Study 17122083 — Biomarker: IGF2R mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF2R; MPRI
Study 1745027 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31640891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26727115 — Biomarker: SSB mRNA
Type: Predictive Biomarker (PRD)
Genes: SSB
Study 24903351 — Biomarker: SLCO2B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 19229988 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17698116 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8677757 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8677757 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8677757 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29602597 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29602597 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25332243 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 16311849 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28263919 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30350398 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8966498 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27123421 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18161210 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12452452 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 6303106 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 27078993 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 15126518 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 11044760 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25249036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23121733 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28901958 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study 28901958 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 24429202 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10766405 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 22454189 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22454189 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16254220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27762648 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27762648 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27762648 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 15542798 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15542798 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9316778 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 9316778 — Biomarker: STIL mRNA
Type: Predictive Biomarker (PRD)
Genes: STIL; SIL
Study 31209428 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 23030566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19959271 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12494164 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6781794 — Biomarker: SERPINA7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA7; TBG
Study 15452587 — Biomarker: GPR50 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPR50
Study 29596951 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 25639838 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16978159 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 2691690 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2691690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 241364 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 25190674 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23232491 — Biomarker: FGFR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 23232491 — Biomarker: FGFR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR2; BEK; KGFR; KSAM
Study 23232491 — Biomarker: FLT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT4; VEGFR3
Study 8399073 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 2868549 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22784926 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20584682 — Biomarker: NTS mRNA
Type: Predictive Biomarker (PRD)
Genes: NTS
Study 1801561 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6141186 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 30524035 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27310568 — Biomarker: C1QL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 17974109 — Biomarker: SLA mRNA
Type: Predictive Biomarker (PRD)
Genes: SLA; SLAP; SLAP1
Study 26686968 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study 25291577 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 19215005 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25908486 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25908486 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25908486 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 24174657 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 17372175 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29845329 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 7619356 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7619356 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30170468 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30170468 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 30170468 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22858124 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 22858124 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 18717569 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 10588987 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 21696738 — Biomarker: PLTP mRNA
Type: Predictive Biomarker (PRD)
Genes: PLTP
Study 21696738 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 16782912 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11119192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9194018 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25575541 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 23513469 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 19880138 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31189785 — Biomarker: EPRS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPRS1; EPRS; GLNS; PARS; QARS; QPRS; PIG32