AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24906584 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 24260145 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 24260145 — Biomarker: TPH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH2; NTPH
Study 19009658 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 19009658 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16456383 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10969106 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8838764 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 3523938 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 23857507 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22784897 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22784897 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22784897 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12793558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9917782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27912104 — Biomarker: MARCKS mRNA
Type: Predictive Biomarker (PRD)
Genes: MARCKS; MACS; PRKCSL
Study 23880971 — Biomarker: TLR2
Type: Predictive Biomarker (PRD)
Genes: TIL4; CD282
Study 23880971 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22084333 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19501587 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 19501587 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 17016233 — Biomarker: CHEK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHEK2; CDS1; CHK2; RAD53
Study 15799931 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 1789813 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29802136 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7915237 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28755409 — Biomarker: GCGR mRNA
Type: Predictive Biomarker (PRD)
Genes: GCGR
Study 18496508 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2573761 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19424051 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17074116 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18191057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18191057 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18191057 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11081343 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22466947 — Biomarker: ST7 mRNA
Type: Predictive Biomarker (PRD)
Genes: ST7; FAM4A1; HELG; RAY1
Study 319541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12811500 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30769128 — Biomarker: SON mRNA
Type: Predictive Biomarker (PRD)
Genes: SON; C21orf50; DBP5; KIAA1019; NREBP; HSPC310; HSPC312
Study 30083962 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 22925276 — Biomarker: TPH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH2; NTPH
Study 22925276 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 1669525 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19587249 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2658525 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 901695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25467016 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25467016 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 18028126 — Biomarker: Fibroblast growth factor 1
Type: Safety Biomarker (SAF)
Genes: FGF1
Study 26556736 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25662545 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25662545 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16639670 — Biomarker: PCLAF mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 14616152 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 11062356 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27338954 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17493418 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17493418 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27816115 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 26978497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24337064 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24337064 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29358433 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 29358433 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 29358433 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22958170 — Biomarker: DNMT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMT1; AIM; CXXC9; DNMT
Study 22958170 — Biomarker: MBD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBD4; MED1
Study 22958170 — Biomarker: TET1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET1; CXXC6; KIAA1676; LCX
Study 12434259 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3513529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27565938 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17030560 — Biomarker: CXCR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR2; IL8RB
Study 17030560 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 9043967 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23921272 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10791849 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 8651843 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 27796131 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23391676 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 19470936 — Biomarker: MDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM2
Study 19470936 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 19470936 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 19470936 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 16422960 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 9732932 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 12672184 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8704438 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 28724846 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17924845 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 15083959 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9831631 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study 24169302 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 16935471 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 8524486 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19850248 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15293890 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9403933 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31551217 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31551217 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 26395762 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26395762 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21811172 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 19622902 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 16677182 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9666867 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8120554 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2803050 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 31017470 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31017470 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31017470 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 16736519 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 8970892 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 8970892 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8970892 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 8970892 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 8970892 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 1728934 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21800004 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 21800004 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 21800004 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21800004 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 15033094 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10681323 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 25815324 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 30280641 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 26120052 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20167847 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20167847 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18499959 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 31017476 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 28387855 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28387855 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23660397 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 14969566 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 26460536 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 16923411 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16086929 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8965290 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25833706 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19066606 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31066177 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 31066177 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27584578 — Biomarker: Argininosuccinate synthase
Type: Safety Biomarker (SAF)
Genes: ASS1; ASS
Study 23263241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14745143 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24519752 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 24519752 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22360924 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20180606 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15944337 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 15944337 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 29231497 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23461841 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 3299090 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3299090 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18187744 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 18187744 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 8352673 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26024110 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 9669432 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30143705 — Biomarker: miR-143
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR143
Study 12828863 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 12828863 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 12828863 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2005733 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30237505 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30237505 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 26773778 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 26773778 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 26773778 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 26773778 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26773778 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20534325 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15863374 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 8717471 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 1648598 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 10802151 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10802151 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10802151 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8858389 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 8858389 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 8858389 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 1353368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6143631 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30235680 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30235680 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24559858 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20620037 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15855216 — Biomarker: GLI2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLI2; THP
Study 15855216 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 11939671 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11939671 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30239824 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30239824 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 16269184 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8422279 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 21073697 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 8759812 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29912357 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 17283264 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17283264 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15197541 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2031076 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2031076 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 23696855 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 27340919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23064592 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 8777336 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8777336 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29249596 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12925454 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 29528793 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29528793 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 24335106 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 24335106 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 31755625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24624861 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 20921019 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16157899 — Biomarker: Peripheral myelin protein 22
Type: Pharmacodynamic Biomarker (PDY)
Genes: PMP22; GAS3
Study 12960539 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10469854 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8896312 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22452841 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 12111046 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22404668 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19938151 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19099975 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7872875 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 31618176 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 27748083 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23482645 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21490144 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 7997846 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7997846 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 30506302 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23794185 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 23794185 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 21849912 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 19641928 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 19641928 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728