AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 17059993 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17059993 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17059993 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1312002 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31239321 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 19685375 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19685375 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19685375 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 19685375 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15234425 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15234425 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15234425 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9091008 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22324939 — Biomarker: GNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNL3; E2IG3; NS
Study 20669673 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20669673 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 18609695 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 12049852 — Biomarker: ALAD mRNA
Type: Predictive Biomarker (PRD)
Genes: ALAD
Study 27513247 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24337079 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study 24337079 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 19223156 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 19223156 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 25876832 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25885986 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17225162 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 11472614 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 3126635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9249638 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 8272333 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 22306290 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18093716 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10632912 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8311533 — Biomarker: GCA mRNA
Type: Predictive Biomarker (PRD)
Genes: GCA; GCL
Study 2423803 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27098346 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24102912 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 10735462 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1392423 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 3904233 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23959209 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23959209 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12860257 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 31482309 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 24160442 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14519176 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 8884548 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1303480 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27055970 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 27055970 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27055970 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 15777554 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15777554 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11170979 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11170979 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 11170979 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 3202339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30175930 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30175930 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29933531 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29933531 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29933531 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 18534287 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18534287 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18534287 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 6751366 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24488324 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 28750828 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19421167 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 30097052 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17846974 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1411248 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29059146 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21930607 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21930607 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 21930607 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 22260988 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 12534644 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 10987609 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 31758080 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 18948032 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 18948032 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18948032 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 15039493 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7870226 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 24666765 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 19546583 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19546583 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19546583 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 11798515 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 9093983 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9093983 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 9093983 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 2282101 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24021551 — Biomarker: GATA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GATA4
Study 24021551 — Biomarker: MYH11 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MYH11; KIAA0866
Study 24021551 — Biomarker: GJA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: GJA5
Study 23527300 — Biomarker: CCR9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR9; GPR28
Study 23527300 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12921628 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 9088585 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7655642 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24024839 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 24024839 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24024839 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 1488321 — Biomarker: GLI2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLI2; THP
Study 1488321 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27430558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18794430 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8775721 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 2901839 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28689678 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25596004 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25596004 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8373876 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 8373876 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 24473387 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24473387 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 24473387 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17698336 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10587413 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 8692528 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15674004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25329433 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25329433 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 25329433 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9440763 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16461376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15876979 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15733514 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 30914102 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30914102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15121491 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3128767 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31891288 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 30638544 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 17317371 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15063607 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17143175 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17143175 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11451721 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8031555 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8031555 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25651245 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18706705 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30105362 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 25440377 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25440377 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 25440377 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 18056193 — Biomarker: NR1I2
Type: Predictive Biomarker (PRD)
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 1980981 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 1980981 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 25577782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19662337 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 19662337 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 8923090 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 25062857 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 14703410 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 8538479 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 8538479 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30419858 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26922296 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25324618 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 25324618 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 9622211 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 9622211 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 7888287 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7888287 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 3352163 — Biomarker: RAPGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 31857313 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 28835380 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 28835380 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 21306916 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 19301201 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19301201 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 11902819 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 7680947 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31574544 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 24235081 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24235081 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 27182021 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27182021 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24019207 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 24019207 — Biomarker: GATA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GATA3
Study 24019207 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19761935 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 19761935 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 9290026 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 2979110 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26268636 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26268636 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26268636 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 20696083 — Biomarker: CXCL1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 20696083 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26211827 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21981269 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 20503800 — Biomarker: Auditory steady-state response
Type: Pharmacodynamic Biomarker (PDY)
Study 7611862 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 7611862 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 7611862 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 23888317 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23888317 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 23888317 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23888317 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19238517 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 11600586 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 8282330 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28978327 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 28978327 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 23209276 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9659350 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 766555 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 29137111 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 23250912 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23250912 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23250912 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 16762939 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18812447 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 17485597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26215480 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22966864 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15876213 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 29852043 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23435861 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16716061 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16716061 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9215516 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9215516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9215516 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8267470 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 23735098 — Biomarker: USH1G mRNA
Type: Predictive Biomarker (PRD)
Genes: USH1G; SANS
Study 23735098 — Biomarker: SKAP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R
Study 16490490 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF