AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 30877209 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29142236 — Biomarker: miR-210
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR210
Study 29142236 — Biomarker: miR-22
Type: Safety Biomarker (SAF)
Genes: MIR22
Study 25441251 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25441251 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25441251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21699432 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18504236 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16426961 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11153621 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29945555 — Biomarker: TNNT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNNT1; TNT
Study 27006113 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 9759984 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9759984 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15042325 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 2720864 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24274771 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22170713 — Biomarker: GATA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GATA4
Study 22170713 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 20691307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12417288 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10520779 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 10520779 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 10520779 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 10520779 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10520779 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 24195291 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21602648 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8448066 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 3298412 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 30237705 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 26565005 — Biomarker: IVNS1ABP mRNA
Type: Predictive Biomarker (PRD)
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068
Study 19861267 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19861267 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15733401 — Biomarker: FGR mRNA
Type: Predictive Biomarker (PRD)
Genes: FGR; SRC2
Study 24574227 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18854748 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16097419 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 16097419 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 11791086 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 10604491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7781871 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7781871 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 30912690 — Biomarker: THBS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: THBS1; TSP; TSP1
Study 18372684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7617869 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 15820533 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23225299 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10710122 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9015796 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 29989185 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 28089902 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18339052 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31722337 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28641925 — Biomarker: GNE mRNA
Type: Predictive Biomarker (PRD)
Genes: GNE; GLCNE
Study 8744700 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8744700 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 31347165 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 31347165 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 31347165 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 26463012 — Biomarker: P4HB mRNA
Type: Predictive Biomarker (PRD)
Genes: P4HB; ERBA2L; PDI; PDIA1; PO4DB
Study 17264174 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14704540 — Biomarker: ESD mRNA
Type: Predictive Biomarker (PRD)
Genes: ESD
Study 11474327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2927302 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28576675 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28576675 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 28576675 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 23859389 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23859389 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 23859389 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 23859389 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 22585697 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 10400422 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 7549366 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31330899 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 25958709 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25432081 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 25432081 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19468030 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 16760197 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 31425478 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26396095 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 26396095 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21237502 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16202482 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 11688554 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21501093 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 21501093 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 26105600 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 21946486 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 19339531 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 10785873 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7802571 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17616470 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 27107672 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 27107672 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 24784698 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9810148 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 9810148 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 31310990 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22022584 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29888581 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 28622156 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1798003 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7039160 — Biomarker: LORICRIN mRNA
Type: Predictive Biomarker (PRD)
Genes: LORICRIN; LOR; LRN
Study 25288340 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21764858 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21764858 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25142571 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22952383 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28886209 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 23841532 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 16000127 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 8596268 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 24038797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21910701 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 21180008 — Biomarker: PPOX
Type: Safety Biomarker (SAF)
Genes: HCRT; OX
Study 9814468 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 23505005 — Biomarker: CA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA3
Study 16859143 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16859143 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11471481 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18476982 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 26511535 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22854412 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22854412 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21726411 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 19562990 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 21075773 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10911769 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 18657672 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11109976 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 11109976 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23044231 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 23044231 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 20392866 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 18263770 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 10561192 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10561192 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 7657848 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7657848 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2750531 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 28846009 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28846009 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 26324672 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25168268 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22361261 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 22361261 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 16288342 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 21980828 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 21980828 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 1827967 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7034617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22823871 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17592102 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17592102 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 16096436 — Biomarker: BMF mRNA
Type: Predictive Biomarker (PRD)
Genes: BMF
Study 31912603 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20877298 — Biomarker: GNB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNB3
Study 20877298 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 20877298 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9835755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7721404 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25329583 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25329583 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15134985 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12420197 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17523399 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15342615 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11532109 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11532109 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11532109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31387559 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 23291105 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25303950 — Biomarker: HOXA10 mRNA
Type: Predictive Biomarker (PRD)
Genes: HOXA10; HOX1H
Study 18983928 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 18983928 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1971170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33376 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22281412 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10450120 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7503082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25261291 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study 19238124 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 15022801 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18207280 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31669136 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 30545134 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 7860310 — Biomarker: Hypoxanthine-guanine phosphoribosyltransferase
Type: Safety Biomarker (SAF)
Genes: HPRT1; HPRT
Study 31056655 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31056655 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28418028 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 27238963 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 17696825 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 14517164 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10996360 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 10996360 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 2671402 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 618025 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31796986 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 27079636 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27079636 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 25727879 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8020904 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 30366945 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 27841912 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24568907 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8562273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22118442 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 29754582 — Biomarker: MAEA mRNA
Type: Predictive Biomarker (PRD)
Genes: MAEA; EMP; HLC10; PIG5
Study 29754582 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 8935693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29678523 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study 25065337 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 24721893 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 15948790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12911202 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12911202 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1925193 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28027794 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25863661 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27612046 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22872467 — Biomarker: NANOS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS3; NOS3
Study 16008680 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 12747278 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12747278 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 4061119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7528908 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 25311256 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 17009253 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 17009253 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 9077495 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 3114548 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24029546 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 20503023 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 28753098 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 25510856 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 25510856 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 8104070 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8104070 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 3006471 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 19363237 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1