AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23390553 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23740460 — Biomarker: C-C motif chemokine 19
Type: Safety Biomarker (SAF)
Genes: CCL19; ELC; MIP3B; SCYA19
Study 23740460 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 23740460 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 23740460 — Biomarker: CXCL13 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL13; BCA1; BLC; SCYB13
Study 8810653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25311296 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25311296 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 25311296 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15963128 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 20418657 — Biomarker: Major prion protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRNP; ALTPRP; PRIP; PRP
Study 18380554 — Biomarker: RGR mRNA
Type: Predictive Biomarker (PRD)
Genes: RGR
Study 18380554 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 10227010 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7075640 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19657698 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 15837446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12203856 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12203856 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9657561 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 16453054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15112279 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 11665788 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 4936366 — Biomarker: CPA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA6; CPAH
Study 23863876 — Biomarker: SLC22A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A2; OCT2
Study 14506952 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8682134 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24736679 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11888840 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11888840 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7661937 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3047333 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 3047333 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 3047333 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 16221219 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 12148101 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 12148101 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22094911 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22094911 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21050476 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17577218 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15037444 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15037444 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1927862 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7037030 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22642740 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22642740 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30572436 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24944249 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22067384 — Biomarker: CD52 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD52; CDW52; HE5
Study 20150021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6146390 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18340565 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 24518078 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22281165 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 22281165 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 17099077 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12039122 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 11088064 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8803300 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1385827 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6364896 — Biomarker: CDCA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDCA4; HEPP
Study 29807945 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 26655888 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9252957 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16632013 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16632013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8139394 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29368598 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11998881 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 9894621 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9894621 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28738490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14618096 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14618096 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 14618096 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 30025819 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27514617 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 24522636 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 18793808 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 18793808 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16144987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12117040 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 2140965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29555631 — Biomarker: CD101 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD101; EWI101; IGSF2; V7
Study 24738800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7290755 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 7290755 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 27717222 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 22028071 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 22028071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22028071 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 22028071 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 2566391 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21834970 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14678587 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1734400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22500389 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22500389 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12859305 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3957482 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3957482 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 17942181 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14624765 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 27652610 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 19848211 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17224344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17224344 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29127842 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 22702846 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21785174 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21785174 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 21785174 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 15496639 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 15496639 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 30153359 — Biomarker: LOXL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LOXL2
Study 26209038 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 26209038 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 26209038 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 24180000 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19014338 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3260083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26333513 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 12708129 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10759770 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3891769 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11407971 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 2888795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18812325 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21510527 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18633172 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11236242 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 11236242 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 11236242 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 30067592 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 1623994 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28231835 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 28231835 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 28231835 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 15577178 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27925651 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 22963982 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 7733075 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 7305653 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7305653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22075818 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19656771 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22108523 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18089623 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 18089623 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18089623 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24015666 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 10735688 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24065124 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 21972425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21190455 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21190455 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8835632 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8835632 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 8584604 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 24372155 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 25358424 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 19879596 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17012863 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 21545399 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14756387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20089204 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19127918 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 10918946 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6510452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17252564 — Biomarker: CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR1; C3BR
Study 25070350 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25070350 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16430412 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 16430412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10857518 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30374692 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30374692 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 23141813 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 19952829 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9550531 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7840527 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 3295323 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 25947930 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 12883897 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1826871 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31023403 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31023403 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 31023403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24345165 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 17726460 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 17726460 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11756645 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 17646243 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17646243 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15980691 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8724034 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30010698 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30010698 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30010698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30010698 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24660759 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 10073603 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10073603 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 10073603 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 31089768 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 24067348 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12499320 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 31074823 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25239019 — Biomarker: GNS mRNA
Type: Predictive Biomarker (PRD)
Genes: GNS
Study 21756323 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14679315 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15125484 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24119823 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 30980315 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 16197583 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 9987085 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 2106274 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26635229 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23345581 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23345581 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 18640465 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18640465 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29277099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29277099 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10220941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7027892 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7027892 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 29177434 — Biomarker: FGFR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR2; BEK; KGFR; KSAM
Study 29177434 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study 19755930 — Biomarker: ZMYM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZMYM2; FIM; RAMP; ZNF198
Study 11367689 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28873511 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 24941840 — Biomarker: CXCL16 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL16; SCYB16; SRPSOX; UNQ2759/PRO6714
Study 24941840 — Biomarker: ADAM10 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM10; KUZ; MADM
Study 24941840 — Biomarker: ADAM17 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM17; CSVP; TACE
Study 24941840 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16454441 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15060505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9362403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31029069 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 28622115 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 30739584 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 15879427 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 15879427 — Biomarker: CXCR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR3; GPR9
Study 12794265 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 1464208 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study 31551219 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31551219 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11858378 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)