AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 17473072 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17473072 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16413428 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 11216493 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 9328363 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 8405026 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 8405026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3533372 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20505016 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 18216523 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 3166044 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28039082 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 21872843 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17805064 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 8589024 — Biomarker: TYMS
Type: Predictive Biomarker (PRD)
Genes: Tsase; TMS; HsT422
Study 2102134 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31075314 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 21828950 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 21828950 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 19854375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15911731 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19710195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3408634 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17081400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17081400 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29679660 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 29679660 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 24662322 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22168128 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 17510208 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 17510208 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 3882071 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23846567 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7832387 — Biomarker: RHCE mRNA
Type: Predictive Biomarker (PRD)
Genes: RHCE; RHC; RHE
Study 1977080 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 344850 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 30870235 — Biomarker: SLC18A2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC18A2; SVMT; VMAT2
Study 26686385 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9459332 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9459332 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 7572573 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25375780 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 21772125 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21772125 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 21772125 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18931896 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18931896 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7768249 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 18806833 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 18806833 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 17141945 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 17141945 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 15090958 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27490086 — Biomarker: DSP mRNA
Type: Predictive Biomarker (PRD)
Genes: DSP
Study 9001838 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27021751 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27021751 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17268413 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23952326 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 11922111 — Biomarker: CXADR mRNA
Type: Predictive Biomarker (PRD)
Genes: CXADR; CAR
Study 29393237 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 25056504 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1955620 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 1955620 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24596459 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18066133 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19828532 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19828532 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15605372 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 12460877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31925809 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31925809 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26749529 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 18538098 — Biomarker: CNDP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNDP2; CN2; CPGL; HEL-S-13; PEPA
Study 26700214 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23852695 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 20137768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18030231 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 11902250 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30513347 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 19060001 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19060001 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15570242 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 15570242 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 9633671 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 23537708 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 18188694 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 18188694 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16896785 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16896785 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7514237 — Biomarker: AIRE mRNA
Type: Predictive Biomarker (PRD)
Genes: AIRE; APECED
Study 18460201 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12663512 — Biomarker: OGG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OGG1; MMH; MUTM; OGH1
Study 12663512 — Biomarker: APEX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 10887107 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10887107 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 1551634 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 2860044 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18044288 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1451730 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1451730 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6331480 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6331480 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29128648 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25294380 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15610070 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 12392582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7493374 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 30844611 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 29231294 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 21672162 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 19106241 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 17454224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28537325 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23692550 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 19366271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9277655 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29080906 — Biomarker: POMC mRNA
Type: Predictive Biomarker (PRD)
Genes: POMC
Study 24820639 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 18351428 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 28043903 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25887569 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study 23213075 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 23213075 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19075102 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19075102 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17824295 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17824295 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31707788 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 31707788 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17224857 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17224857 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17224857 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 9782691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21659972 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 16534012 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 16534012 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12969167 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12969167 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8823331 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8823331 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 1333909 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 6385745 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26792372 — Biomarker: DUSP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DUSP3; VHR
Study 12575396 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 12575396 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2439255 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23293335 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23293335 — Biomarker: New morphometric vertebral fractures
Type: Surrogate Endpoint (SUR)
Study 20825367 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 18288090 — Biomarker: KCNAB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNAB2; KCNA2B; KCNK2
Study 18288090 — Biomarker: SLC18A2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC18A2; SVMT; VMAT2
Study 18288090 — Biomarker: S100A10 mRNA
Type: Predictive Biomarker (PRD)
Genes: S100A10; ANX2LG; CAL1L; CLP11
Study 18288090 — Biomarker: HDAC5 mRNA
Type: Predictive Biomarker (PRD)
Genes: HDAC5; KIAA0600
Study 16547529 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9189647 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9189647 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1439112 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 25904773 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25904773 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 25904773 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 25904773 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 25904773 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25904773 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17997712 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 10673735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30334410 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22574560 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22574560 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 6303001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28216282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19299533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7234648 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31446157 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25576215 — Biomarker: TLR9
Type: Predictive Biomarker (PRD)
Genes: CD289
Study 24079281 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 24079281 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28492279 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 28492279 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 25765952 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 23268837 — Biomarker: miR-34c
Type: Safety Biomarker (SAF)
Genes: MIR34C
Study 23268837 — Biomarker: miR-375
Type: Safety Biomarker (SAF)
Genes: MIR375
Study 21115191 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 19900941 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 19900941 — Biomarker: GSTA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTA1
Study 12825002 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 2279542 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 7002563 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27182005 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 19671802 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 27117144 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27117144 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23965645 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 22973094 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 18600390 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11040232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8121965 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3435906 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30784097 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 30784097 — Biomarker: Platelet count response
Type: Surrogate Endpoint (SUR)
Study 23948786 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 20827510 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22374987 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22374987 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12538431 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 31540384 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 31540384 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 31540384 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 25510857 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 19006463 — Biomarker: CEP70 mRNA
Type: Predictive Biomarker (PRD)
Genes: CEP70; BITE
Study 3056084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26468007 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 15533865 — Biomarker: ACAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAT1; ACAT; MAT
Study 12105160 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 28329121 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23704830 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 23704830 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 23704830 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21422407 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17199134 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 24173029 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22933427 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20530393 — Biomarker: NDP mRNA
Type: Predictive Biomarker (PRD)
Genes: NDP; EVR2
Study 1738183 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 18572041 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 18572041 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18572041 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18572041 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 16093734 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 16093734 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16093734 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10999119 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 10999119 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 12724111 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 15302735 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25441408 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 17513190 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 9689289 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7863833 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21812261 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 16487224 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 16627796 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10588226 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27339446 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 25737517 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17124578 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 8014493 — Biomarker: DHFR
Type: Safety Biomarker (SAF)
Genes: DHFR1
Study 17084803 — Biomarker: PSMB7 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSMB7; Z