AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24618326 — Biomarker: THBS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: THBS1; TSP; TSP1
Study 30569216 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28333288 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28333288 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9856966 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6089950 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30028519 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 12569384 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 12569384 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12569384 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 19958076 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17503172 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21626296 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8986932 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8986932 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 29862877 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 28457847 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 19506195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15671911 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 368852 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25813765 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 9660430 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 30369370 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30369370 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 19539385 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 11834878 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 10428996 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 30948567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25650503 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 15259323 — Biomarker: SPDEF mRNA
Type: Predictive Biomarker (PRD)
Genes: SPDEF; PDEF; PSE
Study 8320931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31473291 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 28819782 — Biomarker: PTGS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGS1; COX1
Study 28819782 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 23848219 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23848219 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 23027887 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15856430 — Biomarker: CYP1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A1
Study 11919725 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study 11252079 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25008392 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 22825089 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20032964 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12868185 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 27756583 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21482968 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 19071236 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 412613 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study 23449826 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23449826 — Biomarker: RAF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAF1; RAF
Study 22066891 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22066891 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 22066891 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22066891 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16141462 — Biomarker: PLTP mRNA
Type: Predictive Biomarker (PRD)
Genes: PLTP
Study 3950827 — Biomarker: PSMB7 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSMB7; Z
Study 10749463 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8932983 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21768463 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 21768463 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 21768463 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 19755462 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 19755462 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 19755462 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19755462 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15310009 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 9154286 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 9154286 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9154286 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29243965 — Biomarker: IDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH2
Study 29243965 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 29243965 — Biomarker: 2-hydroxyglutarate
Type: Pharmacodynamic Biomarker (PDY)
Study 25405014 — Biomarker: MAP9 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP9; ASAP
Study 15223865 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15223865 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 15223865 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15223865 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 8318241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31972249 — Biomarker: TYK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TYK2
Study 31972249 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 31972249 — Biomarker: KRT16 mRNA
Type: Predictive Biomarker (PRD)
Genes: KRT16; KRT16A
Study 31972249 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 31972249 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 30907230 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 27390168 — Biomarker: TNFSF13 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 19597879 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 11339485 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 28281738 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23483064 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18981044 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10939175 — Biomarker: SCGB1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SCGB1A1; CC10; CCSP; UGB
Study 20215710 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19469273 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 1319109 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31525580 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21146673 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 3101502 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21257787 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21257787 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2439800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23301468 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 23301468 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 9163278 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18640991 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 2138973 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2138973 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27688475 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 27688475 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 19254211 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16442924 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 16442924 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15630287 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15630287 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2667859 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23855681 — Biomarker: SH3PXD2A mRNA
Type: Predictive Biomarker (PRD)
Genes: SH3PXD2A; FISH; KIAA0418; SH3MD1; TKS5
Study 11737512 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 9227247 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 12959311 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12959311 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 12959311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30777123 — Biomarker: ZFP57 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZFP57; C6orf40; ZNF698
Study 16538542 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 10920469 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 6692287 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 20191783 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 7077546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23585423 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23519055 — Biomarker: TYRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TYRP1; CAS2; TYRP; TYRRP
Study 23519055 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 10687880 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 10687880 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30257802 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24676373 — Biomarker: CENPJ mRNA
Type: Predictive Biomarker (PRD)
Genes: CENPJ; CPAP; LAP; LIP1
Study 1345141 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26511599 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2548552 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30883882 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30883882 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28086917 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 28086917 — Biomarker: MMP10 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MMP10; STMY2
Study 22826530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17611320 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study 16076946 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 16076946 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15614703 — Biomarker: PRCP mRNA
Type: Predictive Biomarker (PRD)
Genes: PRCP; PCP
Study 31055568 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 28291972 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 17171863 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11361230 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27367436 — Biomarker: CPD mRNA
Type: Predictive Biomarker (PRD)
Genes: CPD
Study 18628485 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10190655 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 2502385 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 30763730 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 30763730 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30763730 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 28419124 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26123068 — Biomarker: DCLRE1C mRNA
Type: Predictive Biomarker (PRD)
Genes: DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C
Study 17712202 — Biomarker: TFG mRNA
Type: Predictive Biomarker (PRD)
Genes: TFG
Study 14739127 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 14739127 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11434163 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 26756859 — Biomarker: SLC25A20 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A20; CAC; CACT
Study 11171786 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11171786 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9416986 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9416986 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3089433 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25972532 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25972532 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27141627 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27141627 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24168956 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19957513 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 30500603 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20370474 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17645592 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17645592 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17645592 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16030154 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 8605328 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31688392 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 27261988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6414253 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6414253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29097388 — Biomarker: ALDH1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH1A2; RALDH2
Study 29097388 — Biomarker: AQP9 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP9; SSC1
Study 29097388 — Biomarker: LIPC mRNA
Type: Predictive Biomarker (PRD)
Genes: LIPC; HTGL
Study 24560012 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11606014 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27539273 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 12851517 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12851517 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12851517 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12851517 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10541926 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8672412 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29079458 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29079458 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 10669911 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 23212700 — Biomarker: SOD2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SOD2
Study 23212700 — Biomarker: GPX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPX1
Study 23212700 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 23212700 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15266029 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 18071720 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 30039453 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 22728692 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9509204 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 23390829 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12468608 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 10202827 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27438378 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15519660 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31327701 — Biomarker: RRAD mRNA
Type: Predictive Biomarker (PRD)
Genes: RRAD; RAD
Study 31327701 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16179044 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25070172 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 25070172 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25070172 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25070172 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 22190533 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 12846752 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10714731 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7587700 — Biomarker: ZFP36 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 23325450 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23325450 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23325450 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 23325450 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23325450 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19190344 — Biomarker: TTPA mRNA
Type: Predictive Biomarker (PRD)
Genes: TTPA; TPP1
Study 19190344 — Biomarker: SEC14L2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEC14L2; C22orf6; KIAA1186; KIAA1658
Study 12969098 — Biomarker: ARX mRNA
Type: Predictive Biomarker (PRD)
Genes: ARX
Study 29246363 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2