AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 25128877 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18160764 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3906227 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31690537 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23390092 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 17705990 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 8555550 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28428736 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12661145 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 11479155 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 519960 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31743071 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 28584187 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28629293 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24934402 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 17868757 — Biomarker: STAR mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAR; STARD1
Study 14551893 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 8899386 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study 20152998 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17043639 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 17043639 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 11371279 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 30202946 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30202946 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19332456 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9631846 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28937272 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 23362019 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 23362019 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23362019 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21599573 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10862930 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 8904521 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31056884 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 25308927 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 23911536 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 21736808 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22513081 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 22513081 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24468797 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22629839 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 22629839 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 20173440 — Biomarker: MSN mRNA
Type: Predictive Biomarker (PRD)
Genes: MSN
Study 8655981 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1515957 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1515957 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22248028 — Biomarker: Hypoxia-inducible factor 1-alpha
Type: Predictive Biomarker (PRD)
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 18584415 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18584415 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16198422 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study 12174408 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12174408 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28338503 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18463427 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 18463427 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 16415635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30137647 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27903247 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 27903247 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 27903247 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 15632815 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 10188899 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 30859961 — Biomarker: AMPH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMPH; AMPH1
Study 28981764 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 22814294 — Biomarker: NOTCH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOTCH1; TAN1
Study 19236279 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 10435372 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 8771219 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 9740601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7979291 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28829876 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 18852529 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18852529 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 18852529 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 31136659 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 31136659 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31136659 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28432266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15315996 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 25071111 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 20113387 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 18204347 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 30149537 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18156661 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12878366 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12878366 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 9403744 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8353025 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 15769683 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 9316463 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 9316463 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22309902 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 18388031 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18388031 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18388031 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24641883 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 24641883 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 24984529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15986266 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31911641 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 22659656 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 22659656 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19070356 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7636393 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7636393 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7636393 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 369673 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15496603 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 15496603 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20641058 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 20641058 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 20641058 — Biomarker: KIT
Type: Predictive Biomarker (PRD)
Genes: CD117; SCFR; C-Kit
Study 11770189 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11770189 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11770189 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26498404 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18583430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14734060 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9821034 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 9821034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7651068 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29026141 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31181728 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 28207536 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27547757 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 25112085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23363065 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 10789668 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2779095 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2779095 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21800009 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 21036880 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18408077 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18408077 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31706911 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 11443537 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 11443537 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11443537 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 2837262 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28893130 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 12728215 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 10789595 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9162611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1637574 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 1637574 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11932310 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26217065 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 17142929 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22081474 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17992069 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7019703 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21185503 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21185503 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19552619 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 10023325 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 29334992 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 28549471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30073471 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 17183021 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 7509383 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21358538 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23479321 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23479321 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 28150513 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24968129 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 17699475 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8984133 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8984133 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8984133 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 1665179 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 29915931 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 29915931 — Biomarker: MMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP2; CLG4A
Study 29915931 — Biomarker: PLOD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLOD1; LLH; PLOD
Study 23060628 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 6443576 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 6443576 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 24593826 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 9625399 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29741913 — Biomarker: NOVA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOVA2; ANOVA; NOVA3
Study 15877991 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15877991 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15877991 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 12706322 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12706322 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12706322 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6111525 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31764009 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21560012 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 7962342 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 26241948 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23252875 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 23252875 — Biomarker: RRAD mRNA
Type: Predictive Biomarker (PRD)
Genes: RRAD; RAD
Study 8884861 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 1728634 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 24578449 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24578449 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10463681 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 7969673 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 8872691 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 8872691 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8872691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21593352 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 16834836 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25170994 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22648289 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 22648289 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21753777 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12757533 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 10482155 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1656149 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 6633596 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28651249 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28651249 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15649285 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27353237 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 11293738 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24244656 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21124314 — Biomarker: SLC47A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC47A1; MATE1
Study 21124314 — Biomarker: SLC47A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC47A2; MATE2
Study 21124314 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17162316 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18302459 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 10907363 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10907363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25710119 — Biomarker: FGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF2; FGFB
Study 25710119 — Biomarker: ADRA2A mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRA2A; ADRA2R; ADRAR
Study 12612867 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1376839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28793896 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 10770538 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9581003 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 11505696 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31650328 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28905240 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4603999 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29916784 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12907528 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 30394916 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25596660 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 1319110 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1319110 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23683448 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20673739 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 16505084 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 16505084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7691253 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7691253 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 7691253 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)