AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 27761693 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 11255809 — Biomarker: CHM mRNA
Type: Predictive Biomarker (PRD)
Genes: CHM; REP1; TCD
Study 9825577 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29510398 — Biomarker: POMC mRNA
Type: Predictive Biomarker (PRD)
Genes: POMC
Study 29510398 — Biomarker: NR3C1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR3C1; GRL
Study 22005660 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10431945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7473523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7473523 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7394143 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31479159 — Biomarker: POLE mRNA
Type: Predictive Biomarker (PRD)
Genes: POLE; POLE1
Study 24754313 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 24754313 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 24754313 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 15015443 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15015443 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 15015443 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 15015443 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 26044463 — Biomarker: FANCE mRNA
Type: Predictive Biomarker (PRD)
Genes: FANCE; FACE
Study 18007568 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 11755953 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 27716690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24249435 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24249435 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21083889 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24504788 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 28663317 — Biomarker: CLC mRNA
Type: Predictive Biomarker (PRD)
Genes: CLC; LGALS10; LGALS10A
Study 28663317 — Biomarker: CPA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA3
Study 28663317 — Biomarker: DNASE1L3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DNASE1L3; DHP2; DNAS1L3
Study 28663317 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 28663317 — Biomarker: ALPL mRNA
Type: Predictive Biomarker (PRD)
Genes: ALPL
Study 28663317 — Biomarker: CXCR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR2; IL8RB
Study 28663317 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 24103283 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22052139 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 1990953 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 30905065 — Biomarker: LGALS3BP mRNA
Type: Predictive Biomarker (PRD)
Genes: LGALS3BP; M2BP
Study 24643911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19423132 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19423132 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2712275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11689731 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25596150 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22429128 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 17355168 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12213884 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 12213884 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study 23294034 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18194386 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 1742750 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 21242674 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 21242674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21242674 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25691084 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30895713 — Biomarker: MSI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MSI1
Study 30895713 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 22829901 — Biomarker: BCAR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCAR1; CAS; CASS1; CRKAS
Study 12076241 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31357534 — Biomarker: CYP27A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP27A1; CYP27
Study 31357534 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 12194936 — Biomarker: FMN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMN1; FMN; LD
Study 8577657 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 30642911 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24603308 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24603308 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19853193 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 3322763 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 12584827 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12584827 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 12584827 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 3510285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26629666 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19134274 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10616846 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7250779 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 16735495 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10731187 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24060350 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 22038880 — Biomarker: SEMG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEMG1; SEMG
Study 17975152 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11973192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10392063 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11317693 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 11317693 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 12685512 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7343274 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28351509 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22992964 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16401653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16401653 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 22905454 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17610348 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17610348 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10200132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2099245 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30744452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20002471 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9740930 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23306586 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18084791 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 10195518 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10195518 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 10195518 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21859820 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19093729 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 19093729 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 18020969 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 18020969 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21471971 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15820070 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 24829414 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24829414 — Biomarker: CCR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 15972319 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15972319 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 15972319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31686981 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31686981 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29888275 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22035805 — Biomarker: SCN9A mRNA
Type: Predictive Biomarker (PRD)
Genes: SCN9A; NENA
Study 20705157 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 10523328 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 10523328 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9333110 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 26657657 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26657657 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 24614125 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 24614125 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24614125 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24614125 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18190629 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 11305719 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 20586997 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 823950 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 25989154 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 23815739 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 18931330 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 3039831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10949003 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19490266 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24875804 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24875804 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20492837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3263508 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 24411642 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 22801017 — Biomarker: CHM mRNA
Type: Predictive Biomarker (PRD)
Genes: CHM; REP1; TCD
Study 11341338 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9760814 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27568890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21560476 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 19702080 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16814691 — Biomarker: DEFA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DEFA1; DEF1; DEFA2; MRS; DEFA1B
Study 28608311 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28608311 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 23808786 — Biomarker: SLC10A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC10A3; DXS253E; P3
Study 21258075 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 18192895 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 18192895 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 23818718 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19339957 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 7515644 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2960473 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25914018 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 28683357 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28683357 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21436683 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8793575 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20739874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20739874 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20739874 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 20739874 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20739874 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16099892 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31196016 — Biomarker: Mitochondrial n-acetylglutamate synthase
Type: Predictive Biomarker (PRD)
Genes: NAGS
Study 28926579 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 21071558 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 21071558 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 18536953 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 11797178 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30354751 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31253441 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 31253441 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27760066 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 17466722 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 15682349 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11737740 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11737740 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 12959320 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 12959320 — Biomarker: DMTN mRNA
Type: Predictive Biomarker (PRD)
Genes: DMTN; DMT; EPB49
Study 12959320 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2827471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25015066 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 25015066 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15957693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10367599 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 10367599 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 7564346 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7564346 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27143273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22433279 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15562127 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 15562127 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15562127 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7875148 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23361871 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 23361871 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 19565135 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12624706 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 7852747 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7852747 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30240132 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 28790038 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 18574688 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 18574688 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 11922398 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 9517631 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16500952 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1788456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19404314 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22435740 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8568290 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 30516102 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27381232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23000523 — Biomarker: CLSTN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLSTN3; CS3; KIAA0726
Study 12188097 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22398243 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 22398243 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 22398243 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20104460 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9594511 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 2687357 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30188220 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 22836073 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22836073 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22836073 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7860392 — Biomarker: COPE mRNA
Type: Predictive Biomarker (PRD)
Genes: COPE
Study 7860392 — Biomarker: TIMM8A mRNA
Type: Predictive Biomarker (PRD)
Genes: TIMM8A; DDP; DDP1; TIM8A
Study 7860392 — Biomarker: SERPINA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 7860392 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 26864458 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17531335 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 373836 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20616218 — Biomarker: CDKN2C mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2C; CDKN6
Study 20616218 — Biomarker: ANP32E mRNA
Type: Predictive Biomarker (PRD)
Genes: ANP32E
Study 20616218 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 31886280 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26514001 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 26514001 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16614398 — Biomarker: ABCG5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG5