AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31664920 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 20956120 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 16846448 — Biomarker: DCT mRNA
Type: Predictive Biomarker (PRD)
Genes: DCT; TYRP2
Study 16846448 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 18942901 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10393376 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 10393376 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8894571 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8236992 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 25967528 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study 26455718 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 2469338 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28004376 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28247686 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 21299254 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21299254 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21299254 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21299254 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 11515892 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28193771 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 12660333 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10971305 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1449107 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19012050 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19012050 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19012050 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 11505044 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31237134 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31237134 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31237134 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31030590 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 28039060 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 23866306 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19125756 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15673989 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 29742145 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 29742145 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25917574 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25917574 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23596051 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 8193524 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29451020 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 19628566 — Biomarker: NCOA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NCOA3; AIB1; BHLHE42; RAC3; TRAM1
Study 19628566 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18469351 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18469351 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 22323351 — Biomarker: HSPA1B mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA1B; HSP72
Study 17382108 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10607256 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 27813347 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 27183124 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27183124 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 17551297 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9655654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27600829 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10933407 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10933407 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 10933407 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 30925267 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 30925267 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 29122812 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25300649 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25300649 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 19083482 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30096092 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 30096092 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29761242 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 16719601 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 8375791 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31451487 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 28485095 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28485095 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28485095 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 20798662 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20798662 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23625090 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 23625090 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23625090 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21543429 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21543429 — Biomarker: SOCS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOCS3; CIS3; SSI3
Study 15155217 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 10764718 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9077538 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16056097 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 7652667 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 23909699 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 18394012 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16842919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26947791 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19583071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3280609 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 31539060 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 31539060 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31539060 — Biomarker: Complement C4
Type: Monitoring Biomarker (MOI)
Study 19268914 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19268914 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 19268914 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11385058 — Biomarker: Alpha-glutathione S-transferase
Type: Safety Biomarker (SAF)
Study 29603219 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 26182759 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 18335728 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 16572429 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9408513 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25566615 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 25566615 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 25566615 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28671626 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28671626 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 24491065 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12029003 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12029003 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12029003 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1653313 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 21441615 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 16318999 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 354916 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28681506 — Biomarker: TLR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR7; UNQ248/PRO285
Study 2493366 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 11704591 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11704591 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9415633 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29763783 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15684311 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 12862418 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30256747 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 27324887 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 18260975 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26001563 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 21618158 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11350882 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 11350882 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 28395758 — Biomarker: Dihydrothymine dehydrogenase
Type: Safety Biomarker (SAF)
Genes: DPYD
Study 21165806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17008146 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 28318835 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 28318835 — Biomarker: Auditory mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 10427139 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 12177657 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12177657 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26318511 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26318511 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 26318511 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10556002 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10556002 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26735531 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 26735531 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22535548 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24063843 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 14970111 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14970111 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11477352 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9570178 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28489032 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28489032 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28489032 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23245622 — Biomarker: RHD mRNA
Type: Predictive Biomarker (PRD)
Genes: RHD
Study 14600188 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1358134 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22356216 — Biomarker: RFC1
Type: Safety Biomarker (SAF)
Genes: A1; PO-GA; RFC140; MHCBFB
Study 22356216 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9604603 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8040762 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24829204 — Biomarker: KLF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLF1; EKLF
Study 22336631 — Biomarker: ADORA2A mRNA
Type: Predictive Biomarker (PRD)
Genes: ADORA2A; ADORA2
Study 22336631 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 22336631 — Biomarker: ADORA2A
Type: Safety Biomarker (SAF)
Genes: RDC8
Study 16291468 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 11991447 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 11991447 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 11991447 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2291869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6106039 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9616533 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 9616533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6107585 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 30735073 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29661563 — Biomarker: HMMR mRNA
Type: Predictive Biomarker (PRD)
Genes: HMMR; IHABP; RHAMM
Study 16778124 — Biomarker: Arachidonate 5-lipoxygenase activating protein
Type: Safety Biomarker (SAF)
Genes: ALOX5AP; FLAP
Study 8222487 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8222487 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31933345 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31752638 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31752638 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31752638 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 22845614 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 17332962 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17332962 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 11274583 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21517801 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 30702226 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24231013 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 18923572 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18923572 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 18923572 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 18923572 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 18923572 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8704693 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24972254 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16099352 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 11587995 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11587995 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11587995 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 7522287 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26349433 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11015147 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22089378 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15837982 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 7836705 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17154786 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 1334792 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12399272 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10410487 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 7595709 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27911471 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 24142232 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22052267 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15531933 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11125853 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 29024304 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15866625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28624580 — Biomarker: HFE mRNA
Type: Predictive Biomarker (PRD)
Genes: HFE; HLAH
Study 19555036 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19555036 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16290998 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25322173 — Biomarker: FURIN mRNA
Type: Predictive Biomarker (PRD)
Genes: FURIN; FUR; PACE; PCSK3
Study 16048569 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10594421 — Biomarker: Alpha-glutathione S-transferase
Type: Safety Biomarker (SAF)
Study 500516 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21550357 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9670269 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7920751 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 29098783 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31549625 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 31549625 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2