AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24755192 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 18294482 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27067393 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 31388184 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 31388184 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29702040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29702040 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29702040 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22134624 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16008934 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 3918145 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22712480 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22712480 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15522901 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12576840 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 31689480 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27761657 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 27761657 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 27761657 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 27761657 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 27761657 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 27761657 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 27761657 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18619520 — Biomarker: LSS mRNA
Type: Predictive Biomarker (PRD)
Genes: LSS; OSC
Study 30911917 — Biomarker: CHM mRNA
Type: Predictive Biomarker (PRD)
Genes: CHM; REP1; TCD
Study 29847468 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 29847468 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 19396947 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 19396947 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19396947 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 29070025 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 19629889 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16388789 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16388789 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7803945 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7803945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3190040 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29778251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16580422 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 2822797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28153938 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19403954 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 7667819 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 25799193 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 25799193 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16176337 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12939217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21951682 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18504393 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 17140161 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20187284 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 20187284 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 20187284 — Biomarker: MYOD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYOD1; BHLHC1; MYF3; MYOD
Study 18165639 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15624096 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 7583806 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2179286 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30944359 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 11254825 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3049338 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11113722 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31238715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20129545 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 27491607 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 31909561 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 30418217 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18171953 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 9892252 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 7841356 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7841356 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 29921730 — Biomarker: IGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF2; PP1446
Study 29921730 — Biomarker: CACNA1G mRNA
Type: Predictive Biomarker (PRD)
Genes: CACNA1G; KIAA1123
Study 29921730 — Biomarker: SOCS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOCS1; SSI1; TIP3
Study 29921730 — Biomarker: RUNX3 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX3; AML2; CBFA3; PEBP2A3
Study 28679643 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20356582 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 12907530 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 11967720 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11967720 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30366577 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 28091446 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 26106113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23266331 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 23266331 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 17418727 — Biomarker: FER mRNA
Type: Predictive Biomarker (PRD)
Genes: FER; TYK3
Study 17418727 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7616279 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31407549 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31407549 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31407549 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17719314 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20979675 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8839231 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2123819 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 23623841 — Biomarker: AIP mRNA
Type: Predictive Biomarker (PRD)
Genes: AIP; XAP2
Study 15519288 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 11302460 — Biomarker: RBFOX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBFOX2; FOX2; HRNBP2; RBM9; RTA
Study 19046249 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15531318 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 8072721 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 8072721 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8072721 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21166722 — Biomarker: CD83 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD83
Study 16597078 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22485232 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 15083597 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15083597 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 25034387 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25034387 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 25034387 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 3894971 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23203140 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14508032 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 14508032 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28315283 — Biomarker: TEF mRNA
Type: Predictive Biomarker (PRD)
Genes: TEF; KIAA1655
Study 25688512 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 25688512 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 22390264 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 19205290 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 7775859 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7775859 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 121884 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 23951335 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 23951335 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 11499735 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11499735 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8387151 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 8387151 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2820329 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2820329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27924521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20459404 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20459404 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10598610 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 20388624 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 1538559 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 29702283 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 22991405 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 20415618 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10226125 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 10226125 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8967669 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1725890 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 1725890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11526363 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11526363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28399112 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 28399112 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 23500537 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19216016 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26429398 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26429398 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22946635 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 21658884 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11700399 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8008999 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28804223 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 28804223 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 28804223 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28804223 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 28804223 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28804223 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 28804223 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 31346609 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 29137041 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 10637151 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10637151 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29231607 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 21470248 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9268948 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 8274720 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27629844 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 26677667 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 26677667 — Biomarker: ACTA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACTA1; ACTA
Study 17139367 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 17139367 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 8383874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26061686 — Biomarker: BTN1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BTN1A1; BTN
Study 23752780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12411452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12411452 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12411452 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6411792 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9146858 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 9146858 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 6498701 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 30763661 — Biomarker: MYCN mRNA
Type: Predictive Biomarker (PRD)
Genes: MYCN; BHLHE37; NMYC
Study 2487529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2487529 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 19929597 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20512334 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 20512334 — Biomarker: Ribonucleoside-diphosphate reductase large subunit
Type: Predictive Biomarker (PRD)
Genes: RRM1; RR1
Study 20512334 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 16759924 — Biomarker: IL2RG mRNA
Type: Predictive Biomarker (PRD)
Genes: IL2RG
Study 16759924 — Biomarker: LOXL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LOXL1; LOXL
Study 14657226 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 9209644 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 9209644 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 26553236 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17658393 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2107743 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30239017 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 26547351 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 14748891 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14748891 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 2733125 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2733125 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31074844 — Biomarker: CLC mRNA
Type: Predictive Biomarker (PRD)
Genes: CLC; LGALS10; LGALS10A
Study 20564086 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 20564086 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 12355576 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 20662726 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18760151 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 15903362 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 9796239 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2533763 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31109415 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31109415 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26258314 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21751661 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 21751661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9382669 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28974267 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23980737 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23980737 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 23980737 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23980737 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9085974 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 9085974 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26569364 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 26569364 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26569364 — Biomarker: miR-423
Type: Safety Biomarker (SAF)
Genes: MIR423
Study 26569364 — Biomarker: miR-652
Type: Safety Biomarker (SAF)
Genes: MIR652
Study 26569364 — Biomarker: miR-18a-5p
Type: Safety Biomarker (SAF)
Genes: MIR18A
Study 20393402 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25409596 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 22476643 — Biomarker: FGA mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGA
Study 18765397 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10069786 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28240597 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 10889153 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 1560424 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3904336 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22362849 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11855668 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1