AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 22414635 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22414635 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12243435 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 12243435 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9836029 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17283313 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 16793944 — Biomarker: SERPINA7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA7; TBG
Study 1718756 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20236255 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12373693 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10022424 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31960896 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 24611967 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10215997 — Biomarker: MAP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2
Study 23535137 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 23535137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16877271 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 25722532 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24694475 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8786250 — Biomarker: NAPA mRNA
Type: Predictive Biomarker (PRD)
Genes: NAPA; SNAPA
Study 31449576 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 21852542 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16338193 — Biomarker: SHC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SHC1; SHC; SHCA
Study 31405646 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24355401 — Biomarker: STT3A mRNA
Type: Predictive Biomarker (PRD)
Genes: STT3A; ITM1; TMC
Study 31307651 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 25538152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25538152 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8518372 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28034704 — Biomarker: Gamma-Histone H2AX
Type: Pharmacodynamic Biomarker (PDY)
Genes: H2AX; H2AFX
Study 24024769 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21454723 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 11397883 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11397883 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 9268185 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 9268185 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 15626550 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15626550 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15626550 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11689389 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 9393221 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26507180 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 24418877 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19083462 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14768515 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20032798 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18372722 — Biomarker: PHLPP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PHLPP1; KIAA0606; PHLPP; PLEKHE1; SCOP
Study 28162292 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 3553495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28417279 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28417279 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19092335 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 8250362 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2944136 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3234635 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 31902736 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 31496659 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25963104 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 21968856 — Biomarker: UNG mRNA
Type: Predictive Biomarker (PRD)
Genes: UNG; DGU; UNG1; UNG15
Study 9204512 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 28294373 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23510568 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23510568 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18469238 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 30680975 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 24950218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10868559 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10868559 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30400117 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 22238631 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 20714820 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18508951 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15910012 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 8656680 — Biomarker: CLEC4D mRNA
Type: Predictive Biomarker (PRD)
Genes: CLEC4D; CLECSF8; MCL
Study 14621753 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16082736 — Biomarker: SPR mRNA
Type: Predictive Biomarker (PRD)
Genes: SPR
Study 11374121 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11374121 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31940591 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 31940591 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22303704 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 11134468 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9402542 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 23764181 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19887503 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19887503 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12846705 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31952985 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 8990771 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30409751 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20953063 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2166716 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7106067 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21999398 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21999398 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7484829 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7484829 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28843184 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 25997818 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 25997818 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19167238 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19167238 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 9609411 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 2369792 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 27797015 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19299471 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 19299471 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 19299471 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9623518 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 9623518 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 19779467 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14709947 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 9510662 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 3936908 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 3936908 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 31079938 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 25122645 — Biomarker: RUNX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX2; AML3; CBFA1; OSF2; PEBP2A
Study 25122645 — Biomarker: miR-200c
Type: Safety Biomarker (SAF)
Genes: MIR200C
Study 16379551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16379551 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 10468903 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 2574764 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29588137 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 29588137 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 26268910 — Biomarker: CCR2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCR2; CMKBR2
Study 26268910 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21905248 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17078211 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25137523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2868900 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10435809 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 7812552 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 19153426 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 8866933 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27440543 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 27440543 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27440543 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31145045 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31145045 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31145045 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21106930 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17885010 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15166388 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8305411 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29202548 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23672733 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23088252 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 22410382 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 22410382 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22410382 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 22410382 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 22410382 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 14693623 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9700132 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9700132 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9700132 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9700132 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 9700132 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 30143478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25397623 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 25039273 — Biomarker: Cathepsin S
Type: Pharmacodynamic Biomarker (PDY)
Genes: CTSS
Study 22503610 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15321153 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7197959 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28834330 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26408012 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 21542927 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16206677 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 2403730 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 30122911 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 25120315 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 20184605 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25152604 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20493474 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 15616757 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8814852 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 6376291 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 27003392 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1796618 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23833270 — Biomarker: ABCG2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 20068585 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20068585 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 29754402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29649309 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10901187 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 23814850 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 20633187 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 18230233 — Biomarker: ID1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ID1; BHLHB24; ID
Study 2302935 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30650500 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22309114 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18372683 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 10221441 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30476543 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30476543 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27560946 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 20053533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20053533 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20053533 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31549178 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 22551440 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 22551440 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 17191248 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 9678794 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 30279273 — Biomarker: DKK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DKK3; REIC; UNQ258/PRO295
Study 22924451 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 15833934 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 31023524 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 9531028 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 30869182 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30869182 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29162572 — Biomarker: MHC class I polypeptide-related sequence A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MICA; PERB11.1
Study 23736109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10832071 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10832071 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 25613938 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25613938 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21807052 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 11120907 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 29442148 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 29442148 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 25668998 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24622263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20834187 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11124689 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 11124689 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30277862 — Biomarker: CCL18 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 30277862 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16444998 — Biomarker: GRAMD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRAMD4; DIP; KIAA0767
Study 29728286 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29753321 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 10821130 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10821130 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26136534 — Biomarker: FOXO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXO1; FKHR; FOXO1A
Study 21550532 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 17805217 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 29202568 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26518870 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26518870 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19748675 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 7719394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31550958 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 28847206 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 28847206 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16696911 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 2433653 — Biomarker: BLM mRNA
Type: Predictive Biomarker (PRD)
Genes: BLM; RECQ2; RECQL3
Study 24754065 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1326165 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2