AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 25514303 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22462635 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 18683786 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 18683786 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 18683786 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 26552756 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 19386052 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15203432 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16634738 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 31295270 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26426352 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 26426352 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 16466172 — Biomarker: CHM mRNA
Type: Predictive Biomarker (PRD)
Genes: CHM; REP1; TCD
Study 12833109 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 12833109 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1998314 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 20634742 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31000233 — Biomarker: GDA mRNA
Type: Predictive Biomarker (PRD)
Genes: GDA; KIAA1258
Study 7715258 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2516609 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28124585 — Biomarker: Beta-secretase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: BACE1; BACE; KIAA1149
Study 16780258 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15515752 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 2022477 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 22838957 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 22838957 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 2688071 — Biomarker: EMP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EMP1; B4B; TMP
Study 31594690 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 31594690 — Biomarker: CFTR
Type: Predictive Biomarker (PRD)
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 30537153 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 30537153 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28456108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22706585 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 19935143 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15763433 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15763433 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11452241 — Biomarker: PRCP mRNA
Type: Predictive Biomarker (PRD)
Genes: PRCP; PCP
Study 30919036 — Biomarker: RGS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RGS2; G0S8; GIG31
Study 30919036 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 29546297 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29546297 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 24651746 — Biomarker: FBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBP1; FBP
Study 30507875 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25415807 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 14707470 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 14707470 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 6394890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26001339 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 25034652 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25034652 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 12409326 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 2020274 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 2020274 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16842977 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14998561 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 14998561 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 30499511 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30499511 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 20151772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9172968 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 31096121 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 26194270 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 8703460 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23336248 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 21315203 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16987384 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8381800 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 26631000 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9106558 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 25483416 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 28680858 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 22152833 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 12576412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11910049 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2044652 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 31353759 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 26976426 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 26976426 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26976426 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 26976426 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26976426 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 18760765 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 10814631 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21739259 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 21739259 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 21739259 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20950883 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17659159 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17659159 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23022464 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 21807321 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21807321 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21807321 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21807321 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12745612 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11081892 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 11081892 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 3159163 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20498393 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 18356346 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11228380 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 30441880 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 30441880 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10634839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30208394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24889399 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 11903856 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 9477010 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9477010 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19945857 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19945857 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12545147 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 10535881 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 7974899 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 28770947 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20689465 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2479187 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 28762527 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 28762527 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8222651 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26591200 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21627558 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 12679710 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9457388 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15877992 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29630134 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29630134 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24256699 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 1489073 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 1489073 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 17653859 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 10729389 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 10729389 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 10729389 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28801122 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 28801122 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28801122 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28801122 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 20705902 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17403578 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 20705534 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10567626 — Biomarker: LTB mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB; TNFC; TNFSF3
Study 30352291 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27612281 — Biomarker: PTH1R mRNA
Type: Predictive Biomarker (PRD)
Genes: PTH1R; PTHR; PTHR1
Study 27612281 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27612281 — Biomarker: New morphometric vertebral fractures
Type: Surrogate Endpoint (SUR)
Study 26257021 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19397693 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19397693 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19397693 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15114043 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28898104 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 26399868 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24617124 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25605283 — Biomarker: Sputum culture conversion to negative
Type: Surrogate Endpoint (SUR)
Study 9345375 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 6297363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21785107 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9397322 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2124925 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30221400 — Biomarker: OLFM4 mRNA
Type: Predictive Biomarker (PRD)
Genes: OLFM4; GW112; UNQ362/PRO698
Study 28241356 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 24281841 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22157845 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20231228 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17664059 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17664059 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16297753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6122098 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 17608790 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study 17608790 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8076564 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9013264 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3877283 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 27391818 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17637782 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 15699445 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19726310 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19726310 — Biomarker: SPN mRNA
Type: Predictive Biomarker (PRD)
Genes: SPN; CD43
Study 15496643 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 17987059 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 17987059 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 11454106 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31352829 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25640526 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 18028460 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12716519 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 15705013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12546641 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 12546641 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12546641 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10844830 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 8872838 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29804469 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 19766403 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9346384 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9346384 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9346384 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28891228 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 15959784 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 29203153 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22075751 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22075751 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12897561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10581665 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 8721800 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8721800 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14613759 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14613759 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14613759 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8602586 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8602586 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30616912 — Biomarker: IKBKG mRNA
Type: Predictive Biomarker (PRD)
Genes: IKBKG; FIP3; NEMO
Study 21329501 — Biomarker: GAL3ST1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAL3ST1; CST
Study 17286150 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17286150 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11118395 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 9701523 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 26059225 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 24228710 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 24228710 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 21624699 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 18774180 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 22246377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20436265 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 20436265 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 27598855 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study 23659362 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 17545881 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30672619 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 23154591 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23154591 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21252014 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21252014 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11125686 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9235523 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 9235523 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19841160 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19841160 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19841160 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19841160 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19841160 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18764914 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18764914 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 14646710 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)