AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 8863992 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 8863992 — Biomarker: Type I cytoskeletal 18 Keratin
Type: Safety Biomarker (SAF)
Genes: KRT18; CYK18; PIG46
Study 30782343 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 30035339 — Biomarker: CFL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CFL1; CFL
Study 18753091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8697930 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 809046 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24725369 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 24183127 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 18259100 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31584739 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 23616506 — Biomarker: MTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 15020604 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9727818 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12888056 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 12510249 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10727543 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10727543 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10727543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6542082 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 19913895 — Biomarker: Carbonic anhydrase IX
Type: Predictive Biomarker (PRD)
Genes: CA9; G250; MN
Study 24222260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25607226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8050210 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 25579292 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18306478 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18306478 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18306478 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16957412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16957412 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10828571 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30421481 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 30421481 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30421481 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26787116 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 15156426 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28689647 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24215511 — Biomarker: Ribonucleoside-diphosphate reductase large subunit
Type: Predictive Biomarker (PRD)
Genes: RRM1; RR1
Study 24215511 — Biomarker: RRM2B mRNA
Type: Predictive Biomarker (PRD)
Genes: RRM2B; P53R2
Study 18165600 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16728515 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 16728515 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8512762 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25981191 — Biomarker: GATA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GATA3
Study 25981191 — Biomarker: Th2 cell
Type: Safety Biomarker (SAF)
Study 25981191 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 10633535 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 15894964 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15894964 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7994982 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 7994982 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 7994982 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 7994982 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study 7994982 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31722313 — Biomarker: ADARB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADARB1; ADAR2; DRADA2; RED1
Study 31722313 — Biomarker: GRIA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIA2; GLUR2
Study 10926587 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 9594145 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 9594145 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9594145 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 29449079 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24997050 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 10027655 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7595704 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28103698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26580986 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 25027109 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19411087 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9741502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28161119 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21951411 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21951411 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19112213 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21358850 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7762498 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 371902 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30706788 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22547439 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12139821 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26555069 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 26555069 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 17347181 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 16797292 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16797292 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15012700 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 15012700 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26519056 — Biomarker: TNF-related weak inducer of apoptosis
Type: Predictive Biomarker (PRD)
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study 26519056 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 26519056 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26519056 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 17277585 — Biomarker: ADRA2B mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRA2B; ADRA2L1; ADRA2RL1
Study 9750705 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28679524 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28679524 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31564281 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31564281 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31564281 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 19357698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15136065 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28646900 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 15133865 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30823563 — Biomarker: EED mRNA
Type: Predictive Biomarker (PRD)
Genes: EED
Study 17229901 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12774015 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 3710631 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3710631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2554630 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 30415628 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26572686 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 24924261 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 28267470 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25924844 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31967515 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 28893433 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 28893433 — Biomarker: STAT5A mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT5A; STAT5
Study 28893433 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 23079125 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 12087923 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20571496 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20571496 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20571496 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20571496 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10438047 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26440636 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23356886 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 9681723 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 9681723 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 18279048 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 15841403 — Biomarker: SLA mRNA
Type: Predictive Biomarker (PRD)
Genes: SLA; SLAP; SLAP1
Study 19684411 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17335562 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 17335562 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29562260 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 28252533 — Biomarker: Derived neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 28252533 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 28252533 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25466953 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 25466953 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 18308793 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 31343447 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 9718869 — Biomarker: RTEL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RTEL1; C20orf41; KIAA1088; NHL
Study 24251360 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 24251360 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 30142767 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8797643 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 29021322 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20185009 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12133866 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 12133866 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 8958718 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 8958718 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2938871 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 11859853 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11859853 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 2144919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26117402 — Biomarker: APOA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOA5; RAP3; UNQ411/PRO773
Study 22088414 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7821197 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 7821197 — Biomarker: ADA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADA2; ADGF; CECR1; IDGFL
Study 2900816 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26408621 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24461666 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 1611979 — Biomarker: POR mRNA
Type: Predictive Biomarker (PRD)
Genes: POR; CYPOR
Study 1611979 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30456964 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19713225 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19713225 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12920494 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 27993631 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 27993631 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22039668 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22039668 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 7963155 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 2953691 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 2953691 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31748705 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31748705 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 29275402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18504547 — Biomarker: ADIPOQ mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 11063191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30217232 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30217232 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18613251 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 1364197 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23130748 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 23130748 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 21574710 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 23208128 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 23208128 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 8630312 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 8630312 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8630312 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1910103 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27930447 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 12149201 — Biomarker: COL3A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL3A1
Study 8729674 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 8729674 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 14618093 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 14618093 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10868622 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study 16447879 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 16447879 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 23969334 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 28089729 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 28089729 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 24260194 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8252937 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26538631 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 22959497 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 10533157 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24499951 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24499951 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 20673554 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 20673554 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 29212716 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25851629 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15238183 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15238183 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 15238183 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11386854 — Biomarker: TPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH1; TPH; TPRH; TRPH
Study 11386854 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 9219480 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26476074 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 10955373 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10955373 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8808221 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8808221 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 26683683 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 25054594 — Biomarker: WIPF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WIPF1; WASPIP; WIP
Study 22209391 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21942708 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 21942708 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study 21942708 — Biomarker: SERPINA7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA7; TBG
Study 21942708 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 19220089 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2406538 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2406538 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6111083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31228782 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31228782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28587952 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 28587952 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24142687 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 17309946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26654517 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26654517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11390337 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24092547 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 24092547 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF