AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 25938830 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 19804443 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8203183 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 31391092 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 31391092 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28777672 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21931327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24366918 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24366918 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16912957 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 16912957 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 8931749 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8931749 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 8931749 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 19195793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30394006 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18715391 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16542056 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 16542056 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16542056 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16542056 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12850240 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26508702 — Biomarker: MYOD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYOD1; BHLHC1; MYF3; MYOD
Study 26508702 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 23650508 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 8746285 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25118092 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 21297126 — Biomarker: BSG mRNA
Type: Predictive Biomarker (PRD)
Genes: BSG; UNQ6505/PRO21383
Study 26963737 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 26963737 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 11996196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21680990 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 24356886 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 23614845 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15855325 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 15855325 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15855325 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12543751 — Biomarker: ROM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROM1; TSPAN23
Study 22021897 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 19346511 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11229224 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 332607 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9491231 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 29723928 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 16713661 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18782532 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 23331339 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 19476402 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8874977 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27521509 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27521509 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27521509 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26168365 — Biomarker: MTSS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MTSS1; KIAA0429; MIM
Study 18463672 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18463672 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12594698 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8221800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30229462 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12412824 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8569136 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 25210141 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23414448 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21916906 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 18355388 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17167137 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 14566832 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 1350935 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29794793 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 22382341 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10752972 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25539986 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21330457 — Biomarker: SOX5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOX5
Study 11238495 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30688407 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 26976446 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 20061337 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 20061337 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 20061337 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 2193271 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2193271 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26914909 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24636483 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26121561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23874572 — Biomarker: RAB8A mRNA
Type: Predictive Biomarker (PRD)
Genes: RAB8A; MEL; RAB8
Study 3169222 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31162898 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31162898 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 9126668 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9126668 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30757908 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30757908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17097752 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 7661413 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29316905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31654312 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 31002283 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21778330 — Biomarker: ETV4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV4; E1AF; PEA3
Study 21778330 — Biomarker: ETV5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV5; ERM
Study 21778330 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21778330 — Biomarker: DNAJC12 mRNA
Type: Predictive Biomarker (PRD)
Genes: DNAJC12; JDP1
Study 11748517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8302441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22005174 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 15901634 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2500138 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 21813073 — Biomarker: XKR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: XKR4; KIAA1889; XRG4
Study 21813073 — Biomarker: GRIA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIA4; GLUR4
Study 19034126 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16025230 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14728070 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 31132967 — Biomarker: BAD mRNA
Type: Predictive Biomarker (PRD)
Genes: BAD; BBC6; BCL2L8
Study 23955138 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23955138 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 17127704 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 3060429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3060429 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 3060429 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3060429 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20644014 — Biomarker: PLTP mRNA
Type: Predictive Biomarker (PRD)
Genes: PLTP
Study 18928483 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 16352396 — Biomarker: GLO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLO1
Study 11876692 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study 6623019 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1933049 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6786895 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21900595 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 19143021 — Biomarker: HSPA1B mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA1B; HSP72
Study 19143021 — Biomarker: SERPINH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINH1; CBP1; CBP2; HSP47; SERPINH2; PIG14
Study 19143021 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19143021 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19143021 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 28077734 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 22180357 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22180357 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 2856549 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22030224 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22030224 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14687438 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14687438 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 4025299 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26777722 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26777722 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26777722 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26777722 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8694320 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31298705 — Biomarker: ADAM11 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ADAM11; MDC
Study 30641621 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30641621 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30641621 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 30641621 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22019331 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22019331 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22019331 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 22019331 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15194570 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 3203571 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19767761 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11019420 — Biomarker: TYMS
Type: Predictive Biomarker (PRD)
Genes: Tsase; TMS; HsT422
Study 25069991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25069991 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25069991 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25069991 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16563281 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 16563281 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31883845 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 31883845 — Biomarker: KRT16 mRNA
Type: Predictive Biomarker (PRD)
Genes: KRT16; KRT16A
Study 16600934 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 8773944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1729854 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30537550 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 30537550 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 30537550 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 22150098 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 11864795 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11864795 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11864795 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15451907 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25801162 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23686563 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 9706914 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24677033 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 22952648 — Biomarker: TFAP2B mRNA
Type: Predictive Biomarker (PRD)
Genes: TFAP2B
Study 15339465 — Biomarker: NOS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOS3
Study 23667063 — Biomarker: ERCC2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MAG; EM9; MGC102762; MGC126218; MGC126219
Study 16176939 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9170576 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 20068365 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11281338 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9400948 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9576366 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 9576366 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 26882121 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 26882121 — Biomarker: NR1I2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1I2; PXR
Study 26882121 — Biomarker: NR1I2
Type: Predictive Biomarker (PRD)
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 19480232 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 15143081 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31862436 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10828762 — Biomarker: CGN mRNA
Type: Predictive Biomarker (PRD)
Genes: CGN; KIAA1319
Study 10828762 — Biomarker: PRKD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKD1; PKD; PKD1; PRKCM
Study 21219197 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21219197 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12562650 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12562650 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 9140792 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29667902 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 26815880 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 26815880 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 11591950 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11591950 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 11591950 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11591950 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11591950 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2686711 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30881904 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23460569 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24655694 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22453003 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20038734 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19094763 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 8927288 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6507769 — Biomarker: OTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 17926466 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9794352 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2128265 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 2128265 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2128265 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 110184 — Biomarker: EMB mRNA
Type: Predictive Biomarker (PRD)
Genes: EMB
Study 31492784 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31492784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25827058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24246211 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 24246211 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 21575919 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 21575919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8193987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2464094 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26365445 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24262440 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24262440 — Biomarker: GRB7 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRB7
Study 24262440 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1