AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 27986796 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27989789 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27989886 — Biomarker: SQLE mRNA
Type: Predictive Biomarker (PRD)
Genes: SQLE; ERG1
Study 27989886 — Biomarker: FADS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS1; FADSD5
Study 27989886 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 27989886 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 27989886 — Biomarker: ABCG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG1; ABC8; WHT1
Study 27989886 — Biomarker: DHCR24 mRNA
Type: Predictive Biomarker (PRD)
Genes: DHCR24; KIAA0018
Study 27992268 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 27992451 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27992493 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27993926 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27995485 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 27998223 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 27998970 — Biomarker: FANCD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FANCD2; FACD
Study 27999040 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28003248 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28004304 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 28006063 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28007741 — Biomarker: SMPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMPD1; ASM
Study 28008698 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28009745 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 28010726 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28010726 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 28011051 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 28011608 — Biomarker: Sputum culture conversion to negative
Type: Surrogate Endpoint (SUR)
Study 28011903 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 28013265 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 28013265 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28013405 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 28017350 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28017967 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 28027590 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 28029055 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 28029055 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28029927 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 28031860 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 28032129 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 28032129 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 28032129 — Biomarker: ROS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROS1; MCF3; ROS
Study 28032323 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 28034899 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 28034990 — Biomarker: Aurora kinase A
Type: Predictive Biomarker (PRD)
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 28039155 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 28039229 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 28039295 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 28039295 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 28039295 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 28039295 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 28039367 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 28039367 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 28039367 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 28040992 — Biomarker: TNF-related weak inducer of apoptosis
Type: Predictive Biomarker (PRD)
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study 28040992 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28040992 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28041583 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 28044005 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 28044059 — Biomarker: MTF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MTF2; PCL2
Study 28045622 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 28045622 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 28045712 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28045923 — Biomarker: Angiopoietin 1 receptor
Type: Monitoring Biomarker (MOI)
Genes: TEK; TIE2; VMCM; VMCM1
Study 28045923 — Biomarker: Angiopoietin-1
Type: Monitoring Biomarker (MOI)
Genes: ANGPT1; KIAA0003
Study 28045923 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 28045923 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 28045923 — Biomarker: FGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF2; FGFB
Study 28045923 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28049490 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 28049490 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 28050899 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 28051798 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 28052860 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 28053879 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 28053879 — Biomarker: CD9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD9; MIC3; TSPAN29; GIG2
Study 28053879 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 28053879 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28053879 — Biomarker: NT5E mRNA
Type: Predictive Biomarker (PRD)
Genes: NT5E; NT5; NTE
Study 28054442 — Biomarker: KLRC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRC1; NKG2A
Study 28054442 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 28054442 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28056030 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 28056805 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 28056937 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28057014 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 28057014 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28057654 — Biomarker: ACAD8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAD8; ARC42; IBD
Study 28057664 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28057664 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 28057664 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 28057664 — Biomarker: ERBB4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB4; HER4
Study 28062312 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 28062705 — Biomarker: PAK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAK4; KIAA1142
Study 28063459 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28063459 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28063717 — Biomarker: CAMP mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMP; CAP18; FALL39; HSD26
Study 28065396 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 28065396 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 28065465 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 28065708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28068779 — Biomarker: SLC6A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 28068779 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 28068779 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study 28068779 — Biomarker: HTR1A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR1A; ADRB2RL1; ADRBRL1
Study 28068779 — Biomarker: HTR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2A; HTR2
Study 28068779 — Biomarker: HTR1B mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR1B; HTR1DB
Study 28068779 — Biomarker: HTR2C mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2C; HTR1C
Study 28068779 — Biomarker: TPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH1; TPH; TPRH; TRPH
Study 28068779 — Biomarker: TPH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH2; NTPH
Study 28068899 — Biomarker: FSTL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FSTL1; FRP
Study 28068899 — Biomarker: SORCS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SORCS2; KIAA1329
Study 28068899 — Biomarker: NRF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRF1
Study 28068899 — Biomarker: DLC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DLC1; ARHGAP7; KIAA1723; STARD12
Study 28068899 — Biomarker: PPARGC1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARGC1B; PERC; PGC1; PGC1B; PPARGC1
Study 28068899 — Biomarker: CHN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHN2; ARHGAP3; BCH
Study 28068899 — Biomarker: NXPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXPH1; NPH1; Nbla00697
Study 28069624 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28069838 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 28070266 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 28070266 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 28070715 — Biomarker: SLAMF7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLAMF7; CS1; UNQ576/PRO1138
Study 28070718 — Biomarker: TPBG mRNA
Type: Predictive Biomarker (PRD)
Genes: TPBG; 5T4
Study 28070720 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study 28072473 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 28073769 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 28074139 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28077369 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 28077369 — Biomarker: PHLDA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PHLDA2; BWR1C; HLDA2; IPL; TSSC3
Study 28077384 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28078107 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28078107 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28081178 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28081780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28081780 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28081867 — Biomarker: WNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: WNT2; INT1L1; IRP
Study 28081867 — Biomarker: EN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EN2
Study 28081867 — Biomarker: FOXP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXP2; CAGH44; TNRC10
Study 28082434 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28082434 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28084038 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 28084038 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 28085911 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28086825 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 28086870 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28087181 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 28087540 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28087540 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28089238 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 28089456 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28089456 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28089456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28089635 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 28090295 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 28090299 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 28090332 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28090332 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28090332 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28090332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28090670 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 28094171 — Biomarker: MCCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCCC2; MCCB
Study 28096099 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28096259 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 28096374 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 28100190 — Biomarker: Protein AMBP
Type: Safety Biomarker (SAF)
Genes: AMBP; HCP; ITIL
Study 28100523 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 28100627 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28100627 — Biomarker: Chitinase-3-like protein 1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: CHI3L1
Study 28100627 — Biomarker: Fatty acid binding protein 1
Type: Safety Biomarker (SAF)
Genes: FABP1; FABPL
Study 28101354 — Biomarker: BTC mRNA
Type: Predictive Biomarker (PRD)
Genes: BTC
Study 28103201 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28103831 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28104211 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 28109243 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 28109259 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28110120 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28110770 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 28111758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28111925 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28111925 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28114884 — Biomarker: FGR mRNA
Type: Predictive Biomarker (PRD)
Genes: FGR; SRC2
Study 28114884 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28114884 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28114962 — Biomarker: COPE mRNA
Type: Predictive Biomarker (PRD)
Genes: COPE
Study 28115515 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 28115515 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 28115916 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 28115916 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28118536 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 28118536 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28118823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28119279 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28119295 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28119295 — Biomarker: FCGR3A mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 28119821 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 28120036 — Biomarker: GPC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPC3; OCI5
Study 28121231 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 28122201 — Biomarker: PDE10A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE10A
Study 28123751 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 28123778 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28126272 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 28126272 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 28126272 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28126961 — Biomarker: miR-125b
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28126961 — Biomarker: miR-532-3p
Type: Safety Biomarker (SAF)
Genes: MIR532
Study 28129359 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 28129359 — Biomarker: MMP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP7; MPSL1; PUMP1
Study 28129359 — Biomarker: STK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: STK4; KRS2; MST1
Study 28129359 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28130688 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 28130688 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28131394 — Biomarker: ID1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ID1; BHLHB24; ID
Study 28132793 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28135273 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 28135777 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 28138028 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 28138556 — Biomarker: miR-208a-3p
Type: Safety Biomarker (SAF)
Genes: MIR208A
Study 28138556 — Biomarker: miR-1
Type: Safety Biomarker (SAF)
Study 28138560 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 28139016 — Biomarker: KLK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLK3; APS
Study 28143434 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 28143447 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 28143620 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 28144917 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1