AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT01173042 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01173042 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study NCT03650348 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04181190 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study NCT01549665 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT02804204 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03637153 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT04249947 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00921622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01454544 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT01286662 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study NCT02728102 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT04135820 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study NCT00365495 — Biomarker: UCP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP3; SLC25A9
Study NCT01436422 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT02648880 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02648880 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT02648880 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02648880 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study NCT04037384 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01887262 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02080520 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00005108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03226457 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT03226457 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT03226457 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study NCT03679013 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT01960205 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT03815773 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study NCT00537030 — Biomarker: Serum asparaginase
Type: Surrogate Endpoint (SUR)
Study NCT00288873 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study NCT03688789 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT03048110 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT02793765 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT03578848 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03821701 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT02958579 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01981720 — Biomarker: PRX mRNA
Type: Predictive Biomarker (PRD)
Genes: PRX; KIAA1620
Study NCT02096120 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01558674 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study NCT01762657 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03989713 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study NCT01874574 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT03866408 — Biomarker: CIDEC mRNA
Type: Predictive Biomarker (PRD)
Genes: CIDEC; FSP27
Study NCT03866408 — Biomarker: PNPLA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PNPLA2; ATGL; FP17548
Study NCT03866408 — Biomarker: G0S2 mRNA
Type: Predictive Biomarker (PRD)
Genes: G0S2
Study NCT04656652 — Biomarker: TACSTD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TACSTD2; GA733-1; M1S1; TROP2
Study NCT02751528 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03776643 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT00200499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04643249 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study NCT04643249 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study NCT04643249 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study NCT04643249 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT04643249 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study NCT04643249 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT01117142 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT02694614 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02782741 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT03308903 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study NCT03546361 — Biomarker: CCL21 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL21; SCYA21; UNQ784/PRO1600
Study NCT02492217 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03327675 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04326985 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT01791595 — Biomarker: MCTS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCTS1; MCT1
Study NCT01632332 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00039689 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT02936102 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01676246 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study NCT02926963 — Biomarker: CYBB mRNA
Type: Predictive Biomarker (PRD)
Genes: CYBB; NOX2
Study NCT02926963 — Biomarker: CYBA mRNA
Type: Predictive Biomarker (PRD)
Genes: CYBA
Study NCT02926963 — Biomarker: NCF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NCF2; NOXA2; P67PHOX
Study NCT04149717 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04395768 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT02868437 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT01626846 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study NCT01048203 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study NCT02865564 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03947242 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01938547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03390361 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT02434952 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study NCT03608215 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT00354367 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01307280 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04201496 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT03769844 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT03769844 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03025880 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03025880 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT01221181 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study NCT01221181 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT01635361 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03911193 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT04309422 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03989089 — Biomarker: APOBEC3B mRNA
Type: Predictive Biomarker (PRD)
Genes: APOBEC3B
Study NCT04407962 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04407962 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02804945 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT00941616 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study NCT04214418 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT00663117 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04426825 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04426825 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03033576 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02347449 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT05110209 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT05110209 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02935686 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT04481139 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study NCT03628859 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study NCT00671346 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT04370821 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT03325335 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01463774 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT00304083 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study NCT02049736 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT03356821 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT03557983 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study NCT03557983 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01639261 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT01577030 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03157011 — Biomarker: GSS mRNA
Type: Predictive Biomarker (PRD)
Genes: GSS
Study NCT03841188 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02039362 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT03902145 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT02431312 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study NCT01705080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01257009 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04882020 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04882020 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT04882020 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study NCT04882020 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT02438462 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT04148001 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study NCT02848690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02360774 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT02929342 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study NCT00001869 — Biomarker: TSC2
Type: Predictive Biomarker (PRD)
Genes: tuberin; LAM; PPP1R160
Study NCT01240811 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT01240811 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study NCT03477461 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study NCT00404430 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00827788 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT02432339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02881658 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02881658 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02453087 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT00117169 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT03719430 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study NCT00176865 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study NCT03226080 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT01214993 — Biomarker: SLC22A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A2; OCT2
Study NCT01214993 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT00570258 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT04325828 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study NCT00275522 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT00459511 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study NCT02271282 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT04019678 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study NCT01991197 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT00311688 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT00391456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00739193 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02879877 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study NCT02075437 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study NCT00004074 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00004074 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study NCT03082729 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03082729 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03082729 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03979911 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02355431 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02355431 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT02410161 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT01100840 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01100840 — Biomarker: FGFR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR4; JTK2; TKF
Study NCT01100840 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT01100840 — Biomarker: EML4 mRNA
Type: Predictive Biomarker (PRD)
Genes: EML4; C2orf2; EMAPL4
Study NCT01100840 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT01100840 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT01100840 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT01100840 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study NCT01100840 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT01100840 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study NCT03217578 — Biomarker: Survival motor neuron protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT01772537 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04388917 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT00437606 — Biomarker: GK mRNA
Type: Predictive Biomarker (PRD)
Genes: GK
Study NCT02577835 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06121193 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02315612 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study NCT03485534 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT00684398 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study NCT01822834 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT03164889 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01472393 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00294996 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02178774 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01264263 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01114620 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT04281082 — Biomarker: ABCB4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCB4; MDR3; PGY3
Study NCT02021526 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study NCT03789643 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT03789643 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study NCT00530192 — Biomarker: SH3PXD2A mRNA
Type: Predictive Biomarker (PRD)
Genes: SH3PXD2A; FISH; KIAA0418; SH3MD1; TKS5
Study NCT04435730 — Biomarker: LGALS3BP mRNA
Type: Predictive Biomarker (PRD)
Genes: LGALS3BP; M2BP
Study NCT01651000 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study NCT04478214 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT00000399 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03346369 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study NCT00078013 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study NCT02005848 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT03879499 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03879499 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT04238936 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study NCT06770894 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT06770894 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02979821 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05033249 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT03003234 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study NCT03003234 — Biomarker: NR1I2
Type: Predictive Biomarker (PRD)
Genes: ONR1; PXR; BXR; SXR; PAR2
Study NCT03003234 — Biomarker: NR1H4 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT04726735 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04726735 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03257592 — Biomarker: TSPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPO; BZRP; MBR
Study NCT00931203 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study NCT00413608 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT01316146 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study NCT02307227 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03064711 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0