AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 16490490 — Biomarker: SERPINF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINF1; PEDF; PIG35
Study 16490490 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8405695 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28601864 — Biomarker: Hydroxyphenylpyruvate dioxygenase
Type: Safety Biomarker (SAF)
Genes: HPD; PPD
Study 28601864 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28601864 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22992332 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 11225291 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 11225291 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 3925217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10691226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24731671 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 24731671 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 23332800 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 16427861 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 10697448 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 29652169 — Biomarker: CXADR mRNA
Type: Predictive Biomarker (PRD)
Genes: CXADR; CAR
Study 15765628 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15765628 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7741138 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2297462 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29065193 — Biomarker: DRD3
Type: Safety Biomarker (SAF)
Study 26765470 — Biomarker: miR-22
Type: Safety Biomarker (SAF)
Genes: MIR22
Study 26765470 — Biomarker: miR-30a
Type: Safety Biomarker (SAF)
Genes: MIR30A
Study 26765470 — Biomarker: miR-122
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR122
Study 24844551 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 24844551 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16466011 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16466011 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23812762 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 31996311 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 31996311 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23992602 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 12792581 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24845177 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18728175 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 18728175 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14512127 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 30639342 — Biomarker: MAOA mRNA
Type: Predictive Biomarker (PRD)
Genes: MAOA
Study 26636426 — Biomarker: RAB3D mRNA
Type: Predictive Biomarker (PRD)
Genes: RAB3D; GOV; RAB16
Study 22970177 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20233625 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 20233625 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 20233625 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 17341568 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 21412266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17634896 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 372867 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28295451 — Biomarker: CCL20 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL20; LARC; MIP3A; SCYA20
Study 28295451 — Biomarker: CCRL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCRL2; CCR11; CCR6; CKRX; CRAM; HCR
Study 17050012 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2582838 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26350603 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 23736006 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18506165 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 11027880 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20585106 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29338540 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 29338540 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 27023594 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16571160 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 10639540 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31919989 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28843718 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28843718 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11023502 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 11023502 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 2894973 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20090366 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 26830678 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26830678 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 22211091 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 20663207 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 15854388 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30563789 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 28522637 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23686372 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17708609 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 28652529 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 28652529 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28652529 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26039494 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21747241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17101852 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11452243 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 7924781 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30032274 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30032274 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27216492 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 17944983 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 17944983 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 19656211 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19656211 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11463764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9722222 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 28436727 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25758280 — Biomarker: CCN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCN3; IGFBP9; NOV; NOVH
Study 14713182 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7572943 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 30615666 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23538154 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21565557 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 18795378 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29025835 — Biomarker: GLS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS2; GA
Study 23160656 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7981460 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 7981460 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15513697 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 23742058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9228438 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3880686 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3880686 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 19727956 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10903217 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 27138575 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 27138575 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24620850 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3171790 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28419200 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17875958 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31979305 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25624756 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18350737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18350737 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15361892 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15361892 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2071428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31031050 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 26778346 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26778346 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15341352 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 11180034 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 22930219 — Biomarker: CD79A mRNA
Type: Predictive Biomarker (PRD)
Genes: CD79A; IGA; MB1
Study 10657415 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2878600 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20159247 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 24457184 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 24457184 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20033904 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20033904 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16357522 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 9024949 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 8510087 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8510087 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31302339 — Biomarker: SPX mRNA
Type: Predictive Biomarker (PRD)
Genes: SPX; C12orf39
Study 31302339 — Biomarker: BPIFA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BPIFA1; LUNX; NASG; PLUNC; SPLUNC1; SPURT; UNQ787/PRO1606
Study 26988864 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 12629101 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 27243774 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24485633 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20426780 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 12586806 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10509757 — Biomarker: FMO3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMO3
Study 1753042 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17293637 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19539078 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19539078 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19539078 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19402836 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 24360749 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27583475 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24906174 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22281182 — Biomarker: Nasal potential difference
Type: Pharmacodynamic Biomarker (PDY)
Study 16339692 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 10536647 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8683231 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 28077379 — Biomarker: SFRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SFRP1; FRP; FRP1; SARP2
Study 25975969 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12804020 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12804020 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19465442 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 19465442 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19465442 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 17525499 — Biomarker: CALD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CALD1; CAD; CDM
Study 15202770 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 23512860 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21545068 — Biomarker: REG3A mRNA
Type: Predictive Biomarker (PRD)
Genes: REG3A; HIP; PAP; PAP1
Study 16916429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 13129464 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 29190004 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 27392509 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 24536058 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22849958 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18199863 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12575908 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 7105826 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31575569 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25530465 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 22627477 — Biomarker: DDIT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT4; REDD1; RTP801
Study 17976797 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 17976797 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 8708714 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 30652031 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30652031 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27835716 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 12235506 — Biomarker: RBPMS mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: RBPMS; HERMES
Study 9698813 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25486932 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15015704 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 15015704 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15015704 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27720136 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27720136 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21234859 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21234859 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 16189176 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26763869 — Biomarker: DEPP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DEPP1; C10orf10; DEPP; FIG
Study 12841542 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 12841542 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 12841542 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10807894 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 8862439 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study 1737653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26959509 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20194844 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 16104444 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1692948 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1692948 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 1692948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23845629 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 11467764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21823421 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16688999 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29182037 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 30177485 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 30177485 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19927154 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19927154 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19927154 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 17621602 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 17621602 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17621602 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 6178096 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6178096 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 31160658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30477855 — Biomarker: GSTM1
Type: Safety Biomarker (SAF)
Genes: MU; H-B
Study 26777137 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 9002531 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9002531 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9002531 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29091464 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1