AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23269536 — Biomarker: SLC45A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC45A3; PCANAP6; PRST
Study 23269536 — Biomarker: MSMB mRNA
Type: Predictive Biomarker (PRD)
Genes: MSMB; PRSP
Study 23269536 — Biomarker: KLK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLK3; APS
Study 21881323 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22906130 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 12499885 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 7636320 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26479144 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 21831277 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15312405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9007680 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30144037 — Biomarker: CD52 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD52; CDW52; HE5
Study 26556571 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 11559968 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 9241288 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 22447019 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14578140 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 26917956 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 1639045 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 6440460 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 19042044 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15925032 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 28207516 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26481293 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9642517 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 9642517 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23933006 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 20888091 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 20888091 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 20888091 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12562873 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 3898930 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12068794 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 31448737 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 29241379 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 10712710 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22857752 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 20500899 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 2246098 — Biomarker: ALPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALPK3; KIAA1330; MAK
Study 26491273 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23392463 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 24688618 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17534745 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 16886928 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 16886928 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11112935 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31679186 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 28017170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14973304 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 14973304 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 17318795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14706485 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 9175946 — Biomarker: KCNH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNH2; ERG; ERG1; HERG
Study 4065179 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 31566843 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 27801825 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27801825 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19929980 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19929980 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14675576 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14675576 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30222541 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 30222541 — Biomarker: HINT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HINT1; HINT; PKCI1; PRKCNH1
Study 7668311 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29843528 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 27852684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14531504 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 14531504 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8880817 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26902092 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26902092 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 26902092 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16167789 — Biomarker: Alpha-glutathione S-transferase
Type: Safety Biomarker (SAF)
Study 6147300 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 23175563 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 11100000 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8775351 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 8775351 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8775351 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6724661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17596273 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19207722 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11370797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9198730 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29900829 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20099281 — Biomarker: MTRR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTRR
Study 9919319 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 30322847 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30322847 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 21332375 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 3201506 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25808588 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16691029 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16691029 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14552534 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 31053943 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 24330343 — Biomarker: SRM mRNA
Type: Predictive Biomarker (PRD)
Genes: SRM; SPS1; SRML1
Study 781495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28575274 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26282657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22123798 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26439785 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25317071 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15602501 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 9802935 — Biomarker: SLAMF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLAMF1; SLAM
Study 23318559 — Biomarker: CHRNA7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA7; NACHRA7
Study 21113584 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14716843 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14716843 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 14716843 — Biomarker: C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: C9
Study 14716843 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17997313 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24401051 — Biomarker: STAR mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAR; STARD1
Study 1859490 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6356900 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20185426 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12161488 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10198397 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10198397 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29511965 — Biomarker: CCND1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND1; BCL1; PRAD1
Study 29511965 — Biomarker: miR-122
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR122
Study 23079690 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6143188 — Biomarker: AIP mRNA
Type: Predictive Biomarker (PRD)
Genes: AIP; XAP2
Study 24408116 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24408116 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 12061947 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 23543663 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 23543663 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study 23543663 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 23543663 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 23543663 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19787287 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11561116 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 3034469 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3034469 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25072617 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25072617 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28679142 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 23381685 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 22180523 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 16372352 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 16372352 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 16372352 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 16372352 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8800583 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8800583 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8800583 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1863505 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1863505 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 3137605 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29675430 — Biomarker: FGF7 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF7; KGF
Study 29675430 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29675430 — Biomarker: ACTA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACTA2; ACTSA; ACTVS; GIG46
Study 19589122 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19589122 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19589122 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25555381 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9562159 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8202883 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8202883 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8202883 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 25330161 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15563538 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 12539211 — Biomarker: DRD3
Type: Safety Biomarker (SAF)
Study 10628188 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26871379 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 21777924 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21777924 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 12191852 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2222242 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 360819 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 28260864 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 23260855 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 8880045 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 7197979 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15121876 — Biomarker: TGFB1
Type: Safety Biomarker (SAF)
Genes: CED; TGFbeta
Study 15121876 — Biomarker: LIF mRNA
Type: Predictive Biomarker (PRD)
Genes: LIF; HILDA
Study 15121876 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 15121876 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11448466 — Biomarker: NES mRNA
Type: Predictive Biomarker (PRD)
Genes: NES; Nbla00170
Study 8822534 — Biomarker: USH1G mRNA
Type: Predictive Biomarker (PRD)
Genes: USH1G; SANS
Study 29501363 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 27922288 — Biomarker: Ataxin-3
Type: Pharmacodynamic Biomarker (PDY)
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 17568245 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17568245 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9973020 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1960071 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7988776 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 154749 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 154749 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 30952794 — Biomarker: KLK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLK3; APS
Study 18401214 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16095054 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 16095054 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 2265248 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 27687519 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28480382 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28480382 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 28480382 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 28480382 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 23301057 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 23301057 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 23301057 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11133640 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9643276 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18303486 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 2880811 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18280726 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 1310913 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1310913 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18005286 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 18005286 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 31957838 — Biomarker: ENO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ENO1; ENO1L1; MBPB1; MPB1
Study 26782685 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22288732 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 22288732 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7886648 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23507258 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31832778 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 26733110 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17650794 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 17650794 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31701610 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 27329448 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 29430176 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 20964833 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20964833 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12077742 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12077742 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12077742 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8588499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27489211 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22610853 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22610853 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22610853 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22610853 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 14679674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21392615 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21392615 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)