AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24952700 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24952700 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 24952700 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 15641091 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28914592 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 27085637 — Biomarker: SSB mRNA
Type: Predictive Biomarker (PRD)
Genes: SSB
Study 15580062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8003095 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 20976769 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30991720 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30991720 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30991720 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30991720 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 26336926 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 2190013 — Biomarker: AMPH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMPH; AMPH1
Study 29180855 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 21466532 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21466532 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17298695 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 14662708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11703963 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11703963 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11703963 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9390726 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 3309653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11818769 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7492104 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1826989 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30292773 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 25085517 — Biomarker: DBNL mRNA
Type: Predictive Biomarker (PRD)
Genes: DBNL; CMAP; SH3P7; PP5423
Study 27055965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27055965 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27055965 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20954287 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 20954287 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 16107961 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 7539852 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 7539852 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7539852 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10928302 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4001836 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 21144938 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21144938 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 12198044 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11575576 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18465343 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1391258 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16762982 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 13678868 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30638985 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 28853992 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19122552 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12872150 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 11091498 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11091498 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 3454368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27941973 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 27941973 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24888857 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 20307657 — Biomarker: SLCO1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 18593715 — Biomarker: CHRNB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNB2
Study 8891515 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 1747959 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 25847941 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 22822075 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 22822075 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 22822075 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 16310576 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16310576 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2718706 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2718706 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31285228 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17721103 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14562945 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10477361 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 1655223 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 29528499 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 27464860 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23431348 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18633426 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8606901 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2015727 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31553833 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 15191261 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 31307913 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31307913 — Biomarker: Serum hemoglobin A1C
Type: Surrogate Endpoint (SUR)
Study 31307913 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28645227 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28645227 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25643928 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 10573618 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8706070 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8706070 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 6918402 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18552616 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study 23044236 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11916440 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 11916440 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 11861034 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 10455479 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18218295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17050889 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10933118 — Biomarker: CARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARS1; CARS
Study 3246212 — Biomarker: BLOC1S4 mRNA
Type: Predictive Biomarker (PRD)
Genes: BLOC1S4; CNO
Study 30900815 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30900815 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18046666 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14730412 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 1338525 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24344160 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11472461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11472461 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2930837 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2930837 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28448688 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 23868627 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8236505 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 22464647 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 22464647 — Biomarker: ACAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAT1; ACAT; MAT
Study 16360994 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28550080 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 26494444 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 26494444 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 21148765 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16669849 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 12792293 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 12792293 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 11111206 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8975873 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 20146168 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18780883 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 9122732 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 3781681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27502865 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25335328 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25335328 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25335328 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22215753 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11776606 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 8874334 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17532829 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 10440916 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30991718 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30991718 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25592197 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21368320 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 21368320 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17498486 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17498486 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27736846 — Biomarker: FGD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGD4; FRABP; ZFYVE6
Study 27736846 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 27736846 — Biomarker: TUBB2A mRNA
Type: Predictive Biomarker (PRD)
Genes: TUBB2A; TUBB2
Study 27736846 — Biomarker: EPHA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPHA5; BSK; EHK1; HEK7; TYRO4
Study 17635371 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 28445888 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22204993 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22204993 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22204993 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29020689 — Biomarker: TPPP mRNA
Type: Predictive Biomarker (PRD)
Genes: TPPP; TPPP1
Study 24038561 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30390699 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 24897342 — Biomarker: RYR1
Type: Safety Biomarker (SAF)
Genes: RYR; PPP1R137
Study 24897342 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24897342 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24897342 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8642232 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8642232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7840022 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18430270 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18430270 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18430270 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2772857 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31165721 — Biomarker: FGA mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGA
Study 12385860 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 15743000 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 9040746 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 9040746 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 7684155 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 30672232 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30672232 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 30672232 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17627404 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11152019 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1505560 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2426934 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 12374900 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12374900 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2680273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31132893 — Biomarker: SLC10A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC10A3; DXS253E; P3
Study 29331037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26786929 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 22873651 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22873651 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22873651 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 12037148 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12404164 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 16860807 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16860807 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16860807 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 16860807 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 14969666 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 24166522 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17708161 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 11521723 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 3285731 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25111236 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 25111236 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21954530 — Biomarker: CENPJ mRNA
Type: Predictive Biomarker (PRD)
Genes: CENPJ; CPAP; LAP; LIP1
Study 11153551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9342546 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 3939740 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 26042474 — Biomarker: OPRD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OPRD1; OPRD
Study 26042474 — Biomarker: OPRK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OPRK1; OPRK
Study 9282973 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 27006510 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24736279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17681081 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 15117739 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9263140 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3545273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27657514 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 24183837 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 24183837 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20525992 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17928878 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6148522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21902692 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 21902692 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 21902692 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 8854471 — Biomarker: ZFP36 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 1291184 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 19817986 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22304443 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 16252734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1876419 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31329855 — Biomarker: APOC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOC3
Study 31329855 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31329855 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26171911 — Biomarker: Angiopoietin-1
Type: Monitoring Biomarker (MOI)
Genes: ANGPT1; KIAA0003
Study 26171911 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 24029303 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24029303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24029303 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24029303 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18193489 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 18193489 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 12969103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1345260 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1