AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 3197370 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29016943 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 24171779 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10929918 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10929918 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23957382 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17161051 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 17161051 — Biomarker: KIT
Type: Predictive Biomarker (PRD)
Genes: CD117; SCFR; C-Kit
Study 8718436 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12756509 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 31309239 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29055242 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 23895296 — Biomarker: NDRG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NDRG1; CAP43; DRG1; RTP
Study 23895296 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21320198 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31150084 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 31150084 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 23312343 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15915004 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 15915004 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 577445 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23397863 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 11895160 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 8535553 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23973636 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12093831 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 9560053 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 28370178 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 26438237 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26438237 — Biomarker: Gamma-Histone H2AX
Type: Pharmacodynamic Biomarker (PDY)
Genes: H2AX; H2AFX
Study 26438237 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 19808351 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 17584566 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15386625 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 8026287 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19954496 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 2869676 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27825738 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 18803955 — Biomarker: ETV6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV6; TEL; TEL1
Study 11974560 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28195933 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 17426157 — Biomarker: DHFR mRNA
Type: Predictive Biomarker (PRD)
Genes: DHFR
Study 17426157 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 17426157 — Biomarker: DHFR
Type: Safety Biomarker (SAF)
Genes: DHFR1
Study 9463638 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 8314135 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 28235621 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 25963985 — Biomarker: SLC38A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC38A3; G17; NAT1; SN1; SNAT3
Study 25963985 — Biomarker: SLC38A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 11713130 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 9385910 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29229305 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 12637791 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 10434822 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 2191769 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 27209164 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27209164 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27209164 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24039147 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 31727154 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 26876425 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22413452 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22605570 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22605570 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7493434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17766739 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 11489708 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 1493935 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30859741 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 24268212 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 22284315 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2572036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 319271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 319271 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 319271 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 319271 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31843335 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 25326135 — Biomarker: FMOD mRNA
Type: Predictive Biomarker (PRD)
Genes: FMOD; FM; SLRR2E
Study 17159017 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11127213 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11127213 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9192993 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9192993 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 7948351 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29086103 — Biomarker: SNAP25 mRNA
Type: Predictive Biomarker (PRD)
Genes: SNAP25; SNAP
Study 18537189 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12860920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10382913 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 2252879 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 19482902 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 30305151 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 21415358 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 6374280 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29452178 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25390695 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25390695 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25390695 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 23075178 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23075178 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 20156909 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 17360171 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16352931 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 7666098 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 19602903 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19602903 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11115036 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 3490803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29248753 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29248753 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10406826 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 22991208 — Biomarker: PDE1A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE1A
Study 22991208 — Biomarker: MTARC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MTARC1; MARC1; MOSC1
Study 22991208 — Biomarker: CRIP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CRIP3; CRP3
Study 15757423 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1847721 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27372462 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21855289 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9665214 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24034570 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24034570 — Biomarker: FCMR mRNA
Type: Predictive Biomarker (PRD)
Genes: FCMR; FAIM3; TOSO
Study 9700993 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16713435 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 7962344 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7962344 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25930719 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21865084 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 1424650 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 26964554 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17591032 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17591032 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15501922 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15501922 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 9469359 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 21385602 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 21385602 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 19472440 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 18043308 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18043308 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18043308 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9168215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17301564 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15064315 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 15064315 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 2676558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31515173 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 23574727 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23574727 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 23574727 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 23574727 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23574727 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23574727 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 19845035 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 16706691 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14995150 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17215845 — Biomarker: SLCO1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 17215845 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 17215845 — Biomarker: SLCO2B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 15164249 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29479906 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 11087700 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 3512970 — Biomarker: TIMM8A mRNA
Type: Predictive Biomarker (PRD)
Genes: TIMM8A; DDP; DDP1; TIM8A
Study 31023842 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 20192619 — Biomarker: EDA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDA; ED1; EDA2
Study 18184544 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18184544 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8136110 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8136110 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2644532 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27768831 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21788632 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15287932 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15287932 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10924631 — Biomarker: MEA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MEA1; MEA
Study 10924631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6360414 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16807272 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16807272 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16807272 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 10340921 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 1793154 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 17310957 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17310957 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20051618 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 11558858 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9755543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9755543 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 21597220 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 10873076 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20868279 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18778120 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 14624421 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29282574 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27697758 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 24241095 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2232062 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2232062 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14993491 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2853749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24050942 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 24050942 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21144559 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 8956793 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 30615058 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30615058 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30615058 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29373094 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 27179795 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24193112 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 8179134 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28800722 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 24028716 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24028716 — Biomarker: FOXP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 14985213 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 14985213 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11687731 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11687731 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24699939 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24699939 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21316934 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21316934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9920100 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7484282 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2301454 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22653877 — Biomarker: SLC46A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC46A1; G21; HCP1; PCFT
Study 2663695 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 26437761 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 21248158 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 31538282 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 28741805 — Biomarker: INPP5J mRNA
Type: Predictive Biomarker (PRD)
Genes: INPP5J; PIB5PA; PIPP
Study 22976217 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 11258039 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19625372 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19625372 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19625372 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19625372 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9786562 — Biomarker: Neurofilament light polypeptide
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: NEFL; NF68; NFL