AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 20576732 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10466476 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26692201 — Biomarker: NRN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRN1; NRN
Study 31613323 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 19427372 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 9249109 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 9249109 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8493215 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20417770 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27751553 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 14742379 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 11167376 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 9459625 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7949265 — Biomarker: ACAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAT1; ACAT; MAT
Study 17287313 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 9880125 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9880125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21925749 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21925749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21925749 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 21925749 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22673924 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11444416 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 28685353 — Biomarker: TSPAN12 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN12; NET2; TM4SF12; UNQ774/PRO1568
Study 22922803 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22922803 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7730651 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7730651 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 7730651 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7730651 — Biomarker: CD7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD7
Study 20152345 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30060746 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30060746 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 30060746 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30060746 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31292955 — Biomarker: AFM mRNA
Type: Predictive Biomarker (PRD)
Genes: AFM; ALB2; ALBA
Study 20368567 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 24770560 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20609991 — Biomarker: LIF mRNA
Type: Predictive Biomarker (PRD)
Genes: LIF; HILDA
Study 20609991 — Biomarker: GAL3ST1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAL3ST1; CST
Study 15817593 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2137901 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20491816 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 16150199 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 16150199 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 10197493 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 19114612 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 19114612 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11028725 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8068603 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29396978 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23698074 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 23698074 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20966402 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20966402 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22795088 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study 22795088 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 22795088 — Biomarker: SERPINA7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA7; TBG
Study 19625946 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16539642 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8176999 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24560332 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 12205570 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16424411 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11063148 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 9060533 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21171265 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 31792640 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 19655666 — Biomarker: RAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAD1; REC1
Study 19655666 — Biomarker: FEN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FEN1; RAD2
Study 16728521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11303007 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 11303007 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11303007 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26447752 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 23052606 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16826026 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 14520724 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 30725192 — Biomarker: LHB mRNA
Type: Predictive Biomarker (PRD)
Genes: LHB
Study 17987533 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 12173299 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12173299 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 12173299 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 12173299 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12173299 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 10463407 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 28068786 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17101936 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30879186 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25552372 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 17353778 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17353778 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8154506 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21876297 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 30148437 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26617438 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26617438 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 25096178 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22531635 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 18214123 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 26932169 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 20969659 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19679266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8143828 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30368884 — Biomarker: TWIST1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TWIST1; BHLHA38; TWIST
Study 30368884 — Biomarker: SNAI2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SNAI2; SLUG; SLUGH
Study 24493829 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24493829 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 31735613 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 28831752 — Biomarker: EDNRA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDNRA; ETA; ETRA
Study 25281755 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25281755 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 19645964 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 14731173 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 8355505 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 20815183 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 11956450 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25844821 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 21851299 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 21851299 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8637402 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8637402 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 8637402 — Biomarker: MSH4 mRNA
Type: Predictive Biomarker (PRD)
Genes: MSH4
Study 1595533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3927332 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 3927332 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 24072231 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14602771 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14602771 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 23680248 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23680248 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23680248 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25561293 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 14992881 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 3322670 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18349395 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 8933485 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24114865 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 7380584 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22840783 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 15331679 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11247108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30196968 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study 15254055 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 11480629 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21248183 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21248183 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 18978177 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 18978177 — Biomarker: GADD45A mRNA
Type: Predictive Biomarker (PRD)
Genes: GADD45A; DDIT1; GADD45
Study 30864279 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30864279 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21148423 — Biomarker: THBS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: THBS1; TSP; TSP1
Study 21148423 — Biomarker: CD47 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD47; MER6
Study 21148423 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21148423 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 18991190 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7939369 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28882920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10878675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8932264 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27776442 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 27776442 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27776442 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 25012003 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31574151 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 26787567 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 26787567 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19584820 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 16080839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23542157 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23542157 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15316843 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11941377 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 2587847 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 2587847 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 16918719 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 16918719 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 25391864 — Biomarker: CNR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNR1; CNR
Study 25391864 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 17049662 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11484098 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2742469 — Biomarker: ANTXR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANTXR1; ATR; TEM8
Study 18973027 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14762035 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26174323 — Biomarker: NCAM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NCAM1; NCAM
Study 14693162 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 14693162 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31594032 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 26864356 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25270680 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 20814119 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2205342 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30452127 — Biomarker: RARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RARS1; RARS
Study 27973337 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26015372 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9143014 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 21685549 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12782903 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12782903 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1890517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19403640 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9536226 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 9536226 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 19622117 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18614945 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8198024 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3295315 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3295315 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19145638 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17306441 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 26481198 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26200237 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 26200237 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 23549954 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19394939 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19394939 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19660910 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23889363 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 4065193 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31859706 — Biomarker: RAB8A mRNA
Type: Predictive Biomarker (PRD)
Genes: RAB8A; MEL; RAB8
Study 21285287 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 15131541 — Biomarker: TFG mRNA
Type: Predictive Biomarker (PRD)
Genes: TFG
Study 2147631 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2147631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30932719 — Biomarker: NKTR mRNA
Type: Predictive Biomarker (PRD)
Genes: NKTR
Study 28402342 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 21450643 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21450643 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30367939 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30367939 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 30367939 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 30367939 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 21183747 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14734123 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1