AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 25971920 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24224515 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24224515 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 9192123 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 17875819 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15468362 — Biomarker: HSPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPD1; HSP60
Study 11301566 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 31826241 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 31826241 — Biomarker: ELN mRNA
Type: Predictive Biomarker (PRD)
Genes: ELN
Study 31826241 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28379519 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 15947624 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study 8877673 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8877673 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30995665 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 24185114 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 20052358 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20052358 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16221568 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8682929 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 26153159 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23522341 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18656274 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 17330512 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17330512 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11112128 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11112128 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 27400997 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27400997 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27400997 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27400997 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20534324 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23751736 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23751736 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10916520 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10916520 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10916520 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3895595 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 26814686 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 20038728 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19100066 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 19100066 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19100066 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 1635633 — Biomarker: DBI mRNA
Type: Predictive Biomarker (PRD)
Genes: DBI
Study 17992062 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11885548 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2197158 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26098427 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16897236 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 16897236 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30662004 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25836351 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 23380979 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 11212161 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19013107 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12709263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9096989 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 19545680 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 19545680 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19545680 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 19545680 — Biomarker: Urinary total protein
Type: Safety Biomarker (SAF)
Study 15087307 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15087307 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9676145 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2569322 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28877715 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23440694 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23440694 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 23440694 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 15900286 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 7594122 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23816038 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23816038 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20103547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20103547 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16385521 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8865468 — Biomarker: PCLAF mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 29432913 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29432913 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 29432913 — Biomarker: C-X-C motif chemokine 11
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 29432913 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 12110626 — Biomarker: Carbonic anhydrase IX
Type: Predictive Biomarker (PRD)
Genes: CA9; G250; MN
Study 30860682 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22427534 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22427534 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22427534 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8737632 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28884306 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 28884306 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 21649534 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 21649534 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20592125 — Biomarker: Auditory steady-state response
Type: Pharmacodynamic Biomarker (PDY)
Study 12743558 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11783280 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 27430319 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 1346877 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 31092643 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31092643 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20542800 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 15905672 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15839590 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 10616013 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 10616013 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 2055292 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 6667808 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6667808 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 6667808 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 6667808 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28572492 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14997006 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 14997006 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31707465 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28153659 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 18979150 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18979150 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2691694 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21385483 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19670953 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19670953 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19670953 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11347755 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11347755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3540222 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31197867 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 31197867 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 7778548 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 372609 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30601976 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25552279 — Biomarker: SCAMP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SCAMP1; SCAMP
Study 25552279 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14745707 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 23838904 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 3284218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17142216 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12629471 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1588374 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31476786 — Biomarker: FGR mRNA
Type: Predictive Biomarker (PRD)
Genes: FGR; SRC2
Study 31510777 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 10762562 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1348475 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 29164798 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 29164798 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 23359361 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 18206190 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 30049724 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30931835 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 29091568 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29091568 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29091568 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29091568 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23806287 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21558575 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21558575 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12025735 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 7585298 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31927548 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 27855643 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 1852516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28970213 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22747420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20025832 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8862090 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31047857 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 27386745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22164957 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22164957 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22164957 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19930850 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 28662647 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 25125353 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24001251 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 28215835 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 21429706 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 12706639 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 29735967 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26495694 — Biomarker: OPN1SW mRNA
Type: Predictive Biomarker (PRD)
Genes: OPN1SW; BCP
Study 12633548 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12633548 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9209249 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27155210 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 24008587 — Biomarker: THBS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: THBS1; TSP; TSP1
Study 24008587 — Biomarker: CCN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 24008587 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24008587 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3894129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3894129 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 18070144 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18070144 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16480969 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16480969 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 10729395 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 10729395 — Biomarker: PON2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON2
Study 10729395 — Biomarker: PON3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON3
Study 3840743 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3840743 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10234420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30528313 — Biomarker: MCCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCCC2; MCCB
Study 15819302 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 9436937 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 30075546 — Biomarker: PEBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PEBP1; PBP; PEBP
Study 22923662 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16466009 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30036440 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 27151024 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 19430043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22496275 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22496275 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22496275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21899544 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 11070759 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2865725 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27488944 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27488944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22901886 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 16260891 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11382863 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 25488686 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 12790983 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17356989 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16238119 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 12235690 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 30318240 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 25996273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19478547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15321699 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11571244 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study 2468877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26700184 — Biomarker: CX3CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CX3CR1; CMKBRL1; GPR13
Study 26700184 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 26700184 — Biomarker: KLRK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRK1; D12S2489E; NKG2D
Study 21153402 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21153402 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 21153402 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16385401 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21733953 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 22414277 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 22414277 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 15839185 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15839185 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7856987 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29352831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)