AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24211172 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24211172 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23314695 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23314695 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 16210048 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 2473515 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 27188795 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 10569644 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8906516 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1878735 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24707021 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24707021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24707021 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12197195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29476238 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 29476238 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19204509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15059636 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15059636 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7538815 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2177394 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 30229398 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11218929 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 28099236 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28099236 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 28099236 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 28099236 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25847401 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23521170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22039471 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 1097220 — Biomarker: ITPA mRNA
Type: Predictive Biomarker (PRD)
Genes: ITPA; C20orf37; My049; OK/SW-cl.9
Study 17549293 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study 17549293 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 27256575 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18596389 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18596389 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16671363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12110423 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 282051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23490226 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 19628108 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19628108 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19628108 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 19628108 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19628108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26940688 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26940688 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 12829991 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 8857016 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 30439309 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 30439309 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 27050801 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 11576365 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26303195 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10225505 — Biomarker: ZFP36 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 23410138 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18312558 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18312558 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18312558 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17634547 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17634547 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 12445218 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 8765382 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22846686 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17967673 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 19567547 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11165354 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16649224 — Biomarker: ERCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC2; XPD; XPDC
Study 11392165 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 29381229 — Biomarker: GPC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPC3; OCI5
Study 29381229 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 29381229 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22751603 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15158303 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 2914153 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20978247 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 19328860 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16942566 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 10811145 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23490403 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 20886606 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15150203 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 11212974 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11212974 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30989330 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 29118371 — Biomarker: miR-137
Type: Safety Biomarker (SAF)
Genes: MIR137
Study 29118371 — Biomarker: CPLX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPLX1
Study 23114287 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23114287 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19459146 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19459146 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 19459146 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15544576 — Biomarker: TPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH1; TPH; TPRH; TRPH
Study 11153670 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6810527 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 24993934 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24462367 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 24462367 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 19008862 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19008862 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2009894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23539534 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12635671 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12635671 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 12635671 — Biomarker: KCNMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNMA1; KCNMA; SLO
Study 12635671 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 12635671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10848925 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 28440343 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 26400818 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30102338 — Biomarker: FBXO11 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBXO11; FBX11; PRMT9; VIT1; UG063H01
Study 25041620 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 22211683 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15792396 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 7049587 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 7049587 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15904654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7943676 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31648705 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 31648705 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9575599 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8222122 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29426300 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 29426300 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28861980 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 15918822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12911187 — Biomarker: New morphometric vertebral fractures
Type: Surrogate Endpoint (SUR)
Study 10561733 — Biomarker: TNFR1B
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 10561733 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 10561733 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8297564 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8297564 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 8297564 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 12584227 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11021956 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9256871 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 1328400 — Biomarker: GJA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GJA1; GJAL
Study 21463799 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21463799 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 16936991 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16936991 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8453193 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2894489 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19032172 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30591062 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24772594 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12500022 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12500022 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28803333 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 19414053 — Biomarker: EDA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDA; ED1; EDA2
Study 7988196 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7988196 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 7988196 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7988196 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 18387160 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11273797 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 28611897 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 22718278 — Biomarker: HOXB13 mRNA
Type: Predictive Biomarker (PRD)
Genes: HOXB13
Study 27664561 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27664561 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24860173 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19690268 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19690268 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19690268 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 11751742 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11751742 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29708654 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 12768071 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11203592 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 29737256 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28642811 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 23727316 — Biomarker: ANK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANK3
Study 23740935 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 23740935 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 3277419 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31018682 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 19229704 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16846545 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16846545 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16846545 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16846545 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 12775859 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 8403274 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 6587752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18784543 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 12505969 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12212217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8624760 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17667566 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17667566 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16221223 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11834952 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 583022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15265250 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11735866 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11367661 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 11367661 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26721229 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 17392122 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 17392122 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15296685 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10862530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10862530 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10862530 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10862530 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25538086 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 20493430 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20493430 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20493430 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16854276 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16854276 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 8958889 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28639216 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 24568073 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24568073 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 24568073 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24568073 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19551236 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15138687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7913949 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7913949 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 2656133 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 26605505 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 16651205 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 12147926 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9820705 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 9820705 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9820705 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2