AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 11163295 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 29214920 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 21284702 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 30808774 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30808774 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 30808774 — Biomarker: Tumor-infiltrating lymphocyte
Type: Predictive Biomarker (PRD)
Study 30808774 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 9141937 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 29662493 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 20980977 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 20980977 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18093273 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 18093273 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1315644 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3910771 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 20439197 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 11300380 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11300380 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 8510513 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28446441 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11082090 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9367703 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26391465 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 14693733 — Biomarker: SRD5A2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SRD5A2
Study 14693733 — Biomarker: CYP17A1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CYP17A1; CYP17; S17AH
Study 14693733 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 31373418 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31373418 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24202408 — Biomarker: MHC class I polypeptide-related sequence A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MICA; PERB11.1
Study 16722027 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16722027 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16722027 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23827881 — Biomarker: MT1G mRNA
Type: Predictive Biomarker (PRD)
Genes: MT1G; MT1K; MT1M
Study 23827881 — Biomarker: MT2A mRNA
Type: Predictive Biomarker (PRD)
Genes: MT2A; CES1; MT2
Study 19873910 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 17032148 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 9479341 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 8789182 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 23580378 — Biomarker: PICALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PICALM; CALM
Study 11535508 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 9759983 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30741579 — Biomarker: TMEM54 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMEM54; BCLP; CAC1
Study 18541571 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15780456 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 30590716 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28189123 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 28189123 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 23378537 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 17325898 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 23286422 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19074638 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28934191 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 28934191 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 16958775 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26979312 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21593809 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9706918 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11337976 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 11337976 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 2439456 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 2439456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19394618 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12939536 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 12939536 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25316559 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18847584 — Biomarker: GCA mRNA
Type: Predictive Biomarker (PRD)
Genes: GCA; GCL
Study 16373904 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16373904 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31415825 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21992075 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21992075 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19090876 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11023764 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 24684105 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 15808751 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15808751 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18391643 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 18391643 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 1767648 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22716976 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17364552 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 12818406 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12818406 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17573446 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 17573446 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 17573446 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29649425 — Biomarker: Nuclear factor erythroid 2-related factor 2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: NFE2L2; NRF2
Study 29649425 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 28103829 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 26122235 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 26122235 — Biomarker: GYPC mRNA
Type: Predictive Biomarker (PRD)
Genes: GYPC; GLPC; GPC
Study 19419350 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 16765146 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16765146 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3250317 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18359865 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 18359865 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 18359865 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 15076235 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27620995 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 22574592 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9392310 — Biomarker: Alpha-glutathione S-transferase
Type: Safety Biomarker (SAF)
Study 23485887 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 17012299 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31096099 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26733479 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 15753530 — Biomarker: SLC30A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC30A1; ZNT1
Study 15753530 — Biomarker: SLC39A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC39A1; IRT1; ZIP1; ZIRTL; CGI-08; CGI-71
Study 15753530 — Biomarker: SLC39A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC39A4; ZIP4
Study 19308417 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 27911869 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 26216378 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26216378 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 12706932 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12706932 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21543294 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27771800 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 27771800 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 20657084 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 11502918 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 22151005 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17573581 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 21529775 — Biomarker: CST9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CST9; CLM; CTES7A
Study 31050763 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19961638 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 11855773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7374 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30911113 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 29185604 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29185604 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 29185604 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23819226 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14740231 — Biomarker: GSTP1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: GSTP
Study 14740231 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 14740231 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 10863964 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 7968324 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28963915 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9811154 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9811154 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30890552 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9783191 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9783191 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 24163616 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 21373969 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 21373969 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 20228976 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 18525396 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 18525396 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18525396 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 12353340 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12353340 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10577635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21659488 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 21659488 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 21659488 — Biomarker: STAT5A mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT5A; STAT5
Study 21659488 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 21659488 — Biomarker: SOCS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOCS3; CIS3; SSI3
Study 21659488 — Biomarker: PTPN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPN1; PTP1B
Study 16508257 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 16508257 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 16508257 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12722967 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 3536644 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24634333 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 24634333 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 12360101 — Biomarker: NOD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOD2; CARD15; IBD1
Study 29028556 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24981955 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17476007 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10684069 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 10684069 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 22345157 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22345157 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22345157 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 20813685 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6411479 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23173831 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23173831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7926977 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7926977 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 1105630 — Biomarker: CPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPZ
Study 27109623 — Biomarker: C1QL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 11707834 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 25315942 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22755276 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 20798393 — Biomarker: ODC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ODC1
Study 7587688 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31135570 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 25543972 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 17105880 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17105880 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29753420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17121049 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23600368 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23600368 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12666705 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 6789483 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11281560 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9337001 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 23474245 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18728576 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20489689 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20489689 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20489689 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2833920 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2833920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26902851 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 26902851 — Biomarker: CCL22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 24288511 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 24288511 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 8820475 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8820475 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25827654 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16750703 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 30222631 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 27633076 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 17274493 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12812815 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9029412 — Biomarker: ADORA2A
Type: Safety Biomarker (SAF)
Genes: RDC8
Study 28994676 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 14767239 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 14767239 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3121268 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10754364 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 20130232 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 20130232 — Biomarker: CCRL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCRL2; CCR11; CCR6; CKRX; CRAM; HCR
Study 20130232 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19095138 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16213291 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)