AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 3011891 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27788510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24622120 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16671258 — Biomarker: MAX mRNA
Type: Predictive Biomarker (PRD)
Genes: MAX; BHLHD4
Study 12858075 — Biomarker: ADAMTS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 12858075 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 20127419 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19100422 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19100422 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 11551005 — Biomarker: TPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH1; TPH; TPRH; TRPH
Study 9763554 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2969638 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 1385959 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1385959 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28349233 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21330912 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16400058 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 6303373 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29496069 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 10344347 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10344347 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6759059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31152039 — Biomarker: CDS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDS1; CDS
Study 31152039 — Biomarker: COMMD3 mRNA
Type: Predictive Biomarker (PRD)
Genes: COMMD3; BUP; C10orf8
Study 21745374 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19966527 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 19966527 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 2144941 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2144941 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23379537 — Biomarker: PTGDR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 8036824 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 1256687 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27959715 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 27959715 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26189484 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 15581649 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22456602 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18034847 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18034847 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11991884 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9505155 — Biomarker: HM13 mRNA
Type: Predictive Biomarker (PRD)
Genes: HM13; H13; IMP1; PSL3; SPP; MSTP086
Study 2507265 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 799563 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28632204 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 16568143 — Biomarker: LGI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LGI1; EPT; UNQ775/PRO1569
Study 2869679 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31221619 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study 28459508 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 28459508 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 24130088 — Biomarker: SMPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMPD1; ASM
Study 1656040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24695898 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15946614 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 7160549 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 16375656 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 11927789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7649340 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23973701 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23411958 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 10235527 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1698137 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 31226213 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 27923158 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27923158 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27923158 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31657165 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31657165 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21293921 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 18445665 — Biomarker: GHR mRNA
Type: Predictive Biomarker (PRD)
Genes: GHR
Study 16101937 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16101937 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 9740631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20303323 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 11591551 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 9845852 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23794693 — Biomarker: IMPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IMPA1; IMPA
Study 18281378 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18281378 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 16569732 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 10559084 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17612905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7487853 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29659888 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 29659888 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29659888 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26490018 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18451780 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 16170170 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 12952293 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 22732370 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22732370 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15914614 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study 15914614 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 15914614 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15914614 — Biomarker: AGTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study 15914614 — Biomarker: AGTR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AGTR2
Study 1315652 — Biomarker: Proliferation marker protein Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67
Study 26861939 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20462041 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 20462041 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20462041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12419082 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12419082 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12419082 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28119496 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 23283501 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 23283501 — Biomarker: APOA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOA1
Study 23283501 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 23283501 — Biomarker: TCF7L2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCF7L2; TCF4
Study 23283501 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 12971730 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18390971 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 14505991 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23628620 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 15188351 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15188351 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8521306 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31387429 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23316894 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1684749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24646429 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 10395849 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24217934 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8760546 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 29098247 — Biomarker: DKK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DKK1; UNQ492/PRO1008
Study 29098247 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 8020641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24482945 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29127547 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29127547 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29127547 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 9099461 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8402326 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 18544642 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 18544642 — Biomarker: PPP1R15A mRNA
Type: Predictive Biomarker (PRD)
Genes: PPP1R15A; GADD34
Study 18544642 — Biomarker: EIF2AK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: EIF2AK3; PEK; PERK
Study 18544642 — Biomarker: XBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: XBP1; TREB5; XBP2
Study 12742468 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12742468 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 9090787 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9090787 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 9090787 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 27552061 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study 7705152 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 31257407 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23392989 — Biomarker: MECP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MECP2
Study 23392989 — Biomarker: ACSM3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACSM3; SAH
Study 3297772 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22027646 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11834237 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 9568181 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8309029 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8309029 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29614865 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3890872 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 3890872 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3890872 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 15604153 — Biomarker: TBX21 mRNA
Type: Predictive Biomarker (PRD)
Genes: TBX21; TBET; TBLYM
Study 7962327 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23698747 — Biomarker: TAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAP1; ABCB2; PSF1; RING4; Y3
Study 19881358 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 16640105 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9196087 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 6423796 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 25819980 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23183514 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 23183514 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 10432174 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8562738 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22113223 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 16762960 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 16762960 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 16762960 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 16762960 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 31894030 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31894030 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 21194693 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21194693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 13678475 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30266120 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30266120 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30266120 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 24142752 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22324419 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19678781 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19678781 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7014105 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31475696 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 28091647 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23695232 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15296473 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15296473 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10924298 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23275042 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 23275042 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23275042 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 14650364 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 8885912 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29467335 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 24758417 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20626209 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31575509 — Biomarker: CCN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 31575509 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21484037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19466963 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15545348 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15545348 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24634205 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8385525 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8385525 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25231730 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19520690 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 14963719 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11888583 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10207641 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 9552949 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9552949 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26231305 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 16645234 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 16645234 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6086866 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 30922731 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 1981019 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16824149 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 16824149 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 24726166 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 18753099 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18753099 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18753099 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15133864 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 15133864 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 3284341 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28480984 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26609122 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 24384734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16966688 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11103113 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11103113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)