AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 7607717 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2215105 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 2215105 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2215105 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10890384 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19380175 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 12355477 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 12355477 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8698859 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 1679299 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21540805 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8062152 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8062152 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8062152 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2543199 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26866508 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 26866508 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 31546576 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19484669 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12499031 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31667572 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19451281 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2892047 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25613431 — Biomarker: FBN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBN1; FBN
Study 30666799 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30666799 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study 30666799 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 9591742 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 29768465 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 22640986 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11527144 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12944569 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26199198 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 9550542 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 24009749 — Biomarker: Complement factor D
Type: Safety Biomarker (SAF)
Genes: CFD; DF; PFD
Study 21720594 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11748361 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8222513 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 29557487 — Biomarker: SP9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP9
Study 25649051 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 22654433 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11986110 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9607375 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9607375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7612039 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6383749 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 6383749 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27310330 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19961902 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 12856809 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7851278 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28366730 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 23765945 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27423921 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 8613276 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9745451 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 2831524 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 29580733 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29580733 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29580733 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 23090678 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27142448 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24522178 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21313892 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17468586 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11823923 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 9817530 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2674395 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 31259755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31106377 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 31106377 — Biomarker: TLR2
Type: Predictive Biomarker (PRD)
Genes: TIL4; CD282
Study 26135349 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11815428 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11815428 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11815428 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11815428 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21279975 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 17551418 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27615555 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 21501481 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16822585 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 16822585 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11123197 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 9429014 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24087989 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24087989 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19381991 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19381991 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11327443 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21619382 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21619382 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 21619382 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21619382 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16797249 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8416666 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20862711 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20862711 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 20862711 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 11903959 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9815869 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31820121 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30365821 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22155532 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1959365 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25661189 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 25661189 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 20605696 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20605696 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20605696 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 20605696 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 19563059 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 15453552 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 15453552 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11816915 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 9802141 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7543352 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 28429365 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 26027630 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6086181 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30304715 — Biomarker: miR-125b
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17468062 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15131770 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15131770 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15131770 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31361922 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25644342 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 15356432 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 14627176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29898838 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 22764184 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 19013239 — Biomarker: SPARC mRNA
Type: Predictive Biomarker (PRD)
Genes: SPARC; ON
Study 15907404 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6290435 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28874171 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 28870680 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 27760998 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25645166 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24018253 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20142183 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 18181335 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15152270 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 15152270 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8096703 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31704024 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 26327768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8114181 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 3384469 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28225205 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28225205 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22136481 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22136481 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12755456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25818798 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23509040 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8087820 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23740686 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 16884565 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16884565 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 16884565 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 10984368 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 25351016 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 18307772 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 18307772 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18307772 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15756254 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12742466 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10868702 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 8239913 — Biomarker: ZFP36 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 3104124 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18332071 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 10066655 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 19027977 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 19027977 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11975864 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 7852113 — Biomarker: CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR1; C3BR
Study 7852113 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 23706168 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21324992 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15196107 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15196107 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16227143 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9813556 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30503218 — Biomarker: PRKRA mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKRA; PACT; RAX; HSD-14; HSD14
Study 28916164 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 28002035 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28002035 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23297557 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 16255878 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7876509 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 4730188 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28611374 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 25862299 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25862299 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19101235 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17544419 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 16943538 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 16943538 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 1286488 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1286488 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29873953 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 22858403 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21134044 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 12368933 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19728183 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28591675 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 21654268 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 16357094 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16357094 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 9412311 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8487666 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8487666 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 31928490 — Biomarker: IGDCC4 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGDCC4; DDM36; KIAA1628; NOPE
Study 31928490 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27521557 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24569129 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 18427133 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 18427133 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18427133 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18427133 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2612166 — Biomarker: ELK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELK3; NET; SAP2
Study 26961928 — Biomarker: RAD51 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAD51; RAD51A; RECA
Study 26961928 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 17401796 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17401796 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7600477 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 28620678 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28620678 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 28620678 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 12003685 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 26073397 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26073397 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3297895 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 31846016 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31846016 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15086924 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15086924 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 12173297 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9391220 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 7502689 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 354046 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17709712 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11477812 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET