AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 8605053 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30816640 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11908511 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10452629 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2218650 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29493059 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29493059 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 22127230 — Biomarker: FBXO32 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FBXO32
Study 15954913 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15954913 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10636510 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27586249 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 30646102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30646102 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26554661 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 23443441 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 21595575 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 27809637 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27809637 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19578239 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19578239 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27251407 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 25549482 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18092565 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10517046 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 25167350 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9883544 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28156007 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21707911 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 28867335 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14980069 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 29339032 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9623511 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 3335825 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 26419527 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22405570 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 7539625 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 7539625 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 7539625 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study 7539625 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 28263812 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 21584847 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20876669 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11374113 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15278585 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15278585 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 15278585 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15048062 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28808723 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 11401935 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 8214647 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 2871915 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28669606 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 22334806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12694138 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31590426 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17580443 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 17580443 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 11523414 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14584388 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 11068313 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 30654471 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27853876 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26427960 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 23091101 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 26661467 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 12090977 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19378223 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 1930923 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22022222 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15661835 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 12107601 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 31240513 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 19018805 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 19018805 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19018805 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 17846333 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 17846333 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15565603 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 7874374 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 25594611 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 24391768 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 8664843 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6527524 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6527524 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 26608718 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 26608718 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 17617944 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17617944 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7995001 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9792489 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25491384 — Biomarker: CCL22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 8948688 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30934797 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29556618 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 17145253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8905472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1713132 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 21401764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18416823 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18416823 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18416823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9487836 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 24886787 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21798891 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16161944 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8641404 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 8641404 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 1729865 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25201893 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11916912 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 7654506 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2199642 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27569177 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18036362 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 15606434 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15606434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12030732 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 6786069 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20530614 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 8845083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8845083 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2015177 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27571713 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27571713 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22884611 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 2474057 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 23286834 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1505537 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28847205 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28847205 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10586205 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31639321 — Biomarker: CARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARS1; CARS
Study 16963041 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 9417802 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 27048405 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 27048405 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18762502 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19748858 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 19748858 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 9043724 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 9043724 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31761974 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 31761974 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 25693859 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16615418 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 8860064 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1298143 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 19479879 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15094269 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11701687 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9771244 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 31028669 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 31028669 — Biomarker: PLCG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLCG2
Study 18294485 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 7901064 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 31858113 — Biomarker: GRAMD2A mRNA
Type: Predictive Biomarker (PRD)
Genes: GRAMD2A; GRAMD2
Study 31858113 — Biomarker: LOXL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LOXL1; LOXL
Study 31858113 — Biomarker: HTR1B mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR1B; HTR1DB
Study 31858113 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 31858113 — Biomarker: KIF25 mRNA
Type: Predictive Biomarker (PRD)
Genes: KIF25; KNSL3
Study 31858113 — Biomarker: SLC39A14 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC39A14; KIAA0062; ZIP14
Study 18585835 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23658423 — Biomarker: ADIPOQ mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 21874260 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21874260 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12716812 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12716812 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9679720 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8004882 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9425966 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8236030 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 24744165 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 26850449 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20648601 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 29555393 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 29555393 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29555393 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16364838 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10592855 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8572837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6129886 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24680587 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22031171 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22031171 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14678347 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 14678347 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12231083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9844955 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 9844955 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 11855793 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11855793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2831525 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10426835 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 2376246 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 2376246 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27930452 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27930452 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 23368915 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 23368915 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28630396 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28630396 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20932155 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20932155 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 10843450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29948666 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29948666 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28629338 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8403573 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30839013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28335886 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 17554116 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12063011 — Biomarker: SOD2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SOD2
Study 7818160 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7818160 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29967948 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 26014321 — Biomarker: STAR mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAR; STARD1
Study 19554082 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17719320 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8059623 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 3058043 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 25403646 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25403646 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 15284376 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15284376 — Biomarker: Alpha-1-acid glycoprotein 1
Type: Monitoring Biomarker (MOI)
Genes: ORM1; AGP1
Study 8039151 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 12026536 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 31155392 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3105747 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 3105747 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22440371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12234955 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6388901 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22404145 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21063110 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 17559697 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11535549 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9647497 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 9647497 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9647497 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20038402 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15329902 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 8117630 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2868337 — Biomarker: KCNN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNN1; SK
Study 22874424 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 14673758 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4