AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT02331693 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01610609 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04052971 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT03392740 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT03392740 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01906229 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01906229 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study NCT06616428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00051558 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01075048 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT02223793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01469260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01195649 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT05571267 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study NCT05571267 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT05571267 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT01699529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04161391 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT04161391 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study NCT03417791 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT02499224 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study NCT00618293 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study NCT00997334 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00997334 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT02974491 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study NCT02974491 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study NCT03293667 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04296058 — Biomarker: SOX4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOX4
Study NCT04296058 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study NCT04486495 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study NCT04357613 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT04357613 — Biomarker: ABL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABL2; ABLL; ARG
Study NCT03871868 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study NCT00248170 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT02377921 — Biomarker: GNE mRNA
Type: Predictive Biomarker (PRD)
Genes: GNE; GLCNE
Study NCT00488813 — Biomarker: MICU2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MICU2; EFHA1
Study NCT04249674 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study NCT00266708 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03504449 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study NCT00013975 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05124015 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT05124015 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT00698659 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00698659 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT01762488 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03809988 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT03809988 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03809988 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT02286596 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03830021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04408183 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study NCT04146831 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study NCT02034695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00987649 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study NCT00987649 — Biomarker: WAP four-disulfide core domain protein 2
Type: Predictive Biomarker (PRD)
Genes: WFDC2; HE4; WAP5
Study NCT01235377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04781114 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study NCT03347591 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study NCT00754442 — Biomarker: CYP27B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study NCT03111095 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00150696 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02433119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01648283 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study NCT04977661 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT04977661 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study NCT00839124 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study NCT00828620 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT01429090 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01413048 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01906359 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT03475628 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00396331 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00396331 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT03580564 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study NCT02304315 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT02675959 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT01495637 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT03679273 — Biomarker: FOXA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXA2; HNF3B; TCF3B
Study NCT04140058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00363402 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study NCT03803033 — Biomarker: HMMR mRNA
Type: Predictive Biomarker (PRD)
Genes: HMMR; IHABP; RHAMM
Study NCT04470531 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04661826 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT00597259 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT03389256 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03389256 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT03893435 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT05712642 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02329119 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study NCT00578903 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT00122356 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT00122356 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00901355 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05266261 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03421444 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT03421444 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03421444 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00002833 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01132664 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03118180 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT01239472 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT01828658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03059667 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03059667 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03059667 — Biomarker: Tumor-infiltrating lymphocyte
Type: Predictive Biomarker (PRD)
Study NCT01302899 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study NCT00077376 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01497626 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01497626 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04132505 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT03969329 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study NCT04160195 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT01561443 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT04297020 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT01827059 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT00604201 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT00202397 — Biomarker: DCN mRNA
Type: Predictive Biomarker (PRD)
Genes: DCN; SLRR1B
Study NCT00202397 — Biomarker: KCNN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNN1; SK
Study NCT02116517 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00442754 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT03447886 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT03447886 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT03166865 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT00737737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03074864 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01588860 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT02658916 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT00266240 — Biomarker: GK mRNA
Type: Predictive Biomarker (PRD)
Genes: GK
Study NCT03173170 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT00427674 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study NCT02336412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00396461 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study NCT02839668 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02839668 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT02839668 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study NCT02839668 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT03003962 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03003962 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT03003962 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00389779 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00093002 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT01386502 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study NCT03119493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03119493 — Biomarker: Body parameter
Type: Safety Biomarker (SAF)
Study NCT02655055 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01891305 — Biomarker: CYP51A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP51A1; CYP51
Study NCT04412889 — Biomarker: TNFRSF17 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF17; BCM; BCMA
Study NCT04412889 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT03122717 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03046745 — Biomarker: Trefoil factor 3
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TFF3; ITF; TFI
Study NCT00490555 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study NCT01387425 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study NCT01885702 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study NCT03744221 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02333253 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT01760824 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study NCT03889392 — Biomarker: PRKD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKD1; PKD; PKD1; PRKCM
Study NCT03889392 — Biomarker: PKD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PKD2; TRPP2
Study NCT00911755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06490575 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01435447 — Biomarker: CR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR2; C3DR
Study NCT05189314 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study NCT00384384 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study NCT03808870 — Biomarker: BMX mRNA
Type: Predictive Biomarker (PRD)
Genes: BMX
Study NCT03808870 — Biomarker: HDAC8 mRNA
Type: Predictive Biomarker (PRD)
Genes: HDAC8; HDACL1; CDA07
Study NCT00498342 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT00498342 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study NCT00254293 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study NCT02404519 — Biomarker: MGP mRNA
Type: Predictive Biomarker (PRD)
Genes: MGP; MGLAP; GIG36
Study NCT01800526 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study NCT03758482 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00479388 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00479388 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02317653 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03887416 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00466726 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00466726 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT00466726 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT00028535 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study NCT04143295 — Biomarker: SLC16A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC16A2; MCT7; MCT8; XPCT
Study NCT03925896 — Biomarker: PSMB9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSMB9; LMP2; PSMB6i; RING12
Study NCT05969444 — Biomarker: HGD mRNA
Type: Predictive Biomarker (PRD)
Genes: HGD; HGO
Study NCT01949116 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02242318 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02025075 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT04004078 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT05345626 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01157715 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT03447340 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01631526 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study NCT02303314 — Biomarker: TFG mRNA
Type: Predictive Biomarker (PRD)
Genes: TFG
Study NCT03313882 — Biomarker: SCN5A mRNA
Type: Predictive Biomarker (PRD)
Genes: SCN5A
Study NCT02727270 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study NCT04551820 — Biomarker: SPARC mRNA
Type: Predictive Biomarker (PRD)
Genes: SPARC; ON
Study NCT02125513 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study NCT02521818 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study NCT02631876 — Biomarker: Folate receptor alpha
Type: Predictive Biomarker (PRD)
Genes: FOLR1; FOLR
Study NCT02943122 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00937651 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03812419 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT02048839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00309569 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT04654676 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT00599560 — Biomarker: AVPR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AVPR2; ADHR; DIR; DIR3; V2R
Study NCT02457975 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02457975 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT04463134 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT00002787 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT02129647 — Biomarker: NF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF2; SCH
Study NCT02439476 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study NCT02439476 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT02355756 — Biomarker: Dermal blood flow
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04590235 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study NCT00477009 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00462943 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT02942056 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT02942056 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study NCT02942056 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT01094249 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00109759 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study NCT00207194 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00483587 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study NCT00095433 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT03606720 — Biomarker: PGP mRNA
Type: Predictive Biomarker (PRD)
Genes: PGP
Study NCT03216317 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04600349 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study NCT01040663 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02263820 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT04392557 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT00978913 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study NCT02668822 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study NCT00594620 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT06231459 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study NCT06231459 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04119999 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01123655 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00171093 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)