AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 21608223 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21608223 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23412078 — Biomarker: SLC5A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A1; NAGT; SGLT1
Study 23412078 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 17081363 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22202581 — Biomarker: PAX3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAX3; HUP2
Study 20860537 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3891617 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24127698 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 24127698 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 10608477 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16990664 — Biomarker: GAD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD2; GAD65
Study 9483483 — Biomarker: PHC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PHC3; EDR3; PH3
Study 25882743 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 21643812 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 21643812 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21643812 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9356540 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 9356540 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26706023 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26706023 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16735113 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8705152 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 8705152 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8705152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7033016 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31658725 — Biomarker: HFE mRNA
Type: Predictive Biomarker (PRD)
Genes: HFE; HLAH
Study 29202732 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21538380 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 7798537 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 31237335 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 28287751 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8864328 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24458439 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 24458439 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 24458439 — Biomarker: ASXL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASXL1; KIAA0978
Study 24458439 — Biomarker: EZH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EZH2; KMT6
Study 24458439 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 16019102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10848718 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 2878130 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 14749744 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29316715 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21070720 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21070720 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9361342 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 3513564 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31655485 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27508274 — Biomarker: SECTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SECTM1; K12
Study 24691452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22455564 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22455564 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 22455564 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15824294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12854895 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 31323685 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 31323685 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24346155 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 24346155 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 24346155 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 24346155 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 24346155 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21685819 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 19614721 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 19614721 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 12625668 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24864045 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 22266895 — Biomarker: Nasal potential difference
Type: Pharmacodynamic Biomarker (PDY)
Study 7741785 — Biomarker: FANCA mRNA
Type: Predictive Biomarker (PRD)
Genes: FANCA; FAA; FACA; FANCH
Study 19681418 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16385545 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8866535 — Biomarker: NES mRNA
Type: Predictive Biomarker (PRD)
Genes: NES; Nbla00170
Study 31507054 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19447919 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 19447919 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 9753020 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30430209 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 25223267 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25223267 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25223267 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17642233 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10206720 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 2360502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22030577 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18672290 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12694213 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18794543 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 7033745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31805992 — Biomarker: S100A8 mRNA
Type: Predictive Biomarker (PRD)
Genes: S100A8; CAGA; CFAG; MRP8
Study 26372274 — Biomarker: KLF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLF2; LKLF
Study 26372274 — Biomarker: KLF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLF4; EZF; GKLF
Study 23401474 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 23401474 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 23401474 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 23401474 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 23401474 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 20396722 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 7822629 — Biomarker: SLC10A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC10A3; DXS253E; P3
Study 2900819 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20503809 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15189747 — Biomarker: NPL mRNA
Type: Predictive Biomarker (PRD)
Genes: NPL; C1orf13
Study 30105357 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 30105357 — Biomarker: RIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RIT1; RIBB; RIT; ROC1
Study 12845340 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12845340 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22147942 — Biomarker: RAF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAF1; RAF
Study 22147942 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 19124372 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 10556133 — Biomarker: SLPI mRNA
Type: Predictive Biomarker (PRD)
Genes: SLPI; WAP4; WFDC4
Study 10556133 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 10556133 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 6711997 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 29982658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26907728 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 23137805 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 12584832 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 12584832 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 12584832 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24885178 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 24885178 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8780536 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 1600965 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 6389233 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31330804 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 30126458 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22295934 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22295934 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9735391 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 8903669 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8903669 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7630678 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28601388 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 17341993 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20404311 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 20404311 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 15976804 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26062182 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 18341671 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 7522629 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 7522629 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 31356262 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21420888 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16940217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14572169 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 9106924 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26620496 — Biomarker: Aurora kinase A
Type: Predictive Biomarker (PRD)
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 17653058 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17653058 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17653058 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 17653058 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28005265 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 24814500 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16620136 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10979160 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19898595 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 15557008 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2080948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9284850 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 29113986 — Biomarker: SOD2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SOD2
Study 27827328 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 24726142 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24726142 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15882229 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 7740570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1668907 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24894685 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22574612 — Biomarker: IPP mRNA
Type: Predictive Biomarker (PRD)
Genes: IPP; KLHL27
Study 22574612 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18981326 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 10379633 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10379633 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6499895 — Biomarker: MOXD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MOXD1; MOX; UNQ2493/PRO5780
Study 6499895 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26984105 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20506371 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18336547 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16116971 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 1925820 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25144133 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 11288792 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 25853877 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24043457 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31077596 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31077596 — Biomarker: CCR3 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CCR3; CMKBR3
Study 31077596 — Biomarker: CCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR4; CMKBR4
Study 31077596 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 31077596 — Biomarker: CXCR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR3; GPR9
Study 31077596 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 31077596 — Biomarker: CCR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 19333948 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19333948 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19333948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16906265 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9015657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22608892 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 18417083 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12212127 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 12212127 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 21996239 — Biomarker: RAB8A mRNA
Type: Predictive Biomarker (PRD)
Genes: RAB8A; MEL; RAB8
Study 14519140 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29685141 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 26151494 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20436517 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 20436517 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20436517 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 18360781 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29766651 — Biomarker: STIL mRNA
Type: Predictive Biomarker (PRD)
Genes: STIL; SIL
Study 16216530 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16216530 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 16216530 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 4025853 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31290696 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31499457 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 19213680 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30615795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17334380 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 17334380 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15869770 — Biomarker: DHFR
Type: Safety Biomarker (SAF)
Genes: DHFR1
Study 12539108 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 31818636 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 30816066 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 30816066 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 19624554 — Biomarker: EDAR mRNA
Type: Predictive Biomarker (PRD)
Genes: EDAR; DL
Study 18179991 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18179991 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29280483 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 19636975 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19636975 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 12428232 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 21723131 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 16842029 — Biomarker: SEMG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEMG1; SEMG
Study 12970782 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 12970782 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 20924215 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 16084873 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 2146040 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 219471 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 219471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30731195 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 30243062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26174080 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 11807630 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 19010347 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2