AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 16837133 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 12771740 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 6734028 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22900989 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 22900989 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22900989 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19858319 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31429418 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12036673 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7130643 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 31627723 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 26590130 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19843057 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 15848604 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2311588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25041550 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9860152 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9860152 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 7630145 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31079282 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 21357809 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7835781 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 7835781 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 19628570 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 23826157 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23826157 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24351694 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26432508 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 25369006 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25369006 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15972934 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15972934 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14677527 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1439067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1439067 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15824372 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 10402766 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10402766 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8404107 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3777548 — Biomarker: Complement factor D
Type: Safety Biomarker (SAF)
Genes: CFD; DF; PFD
Study 20353120 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 18718815 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12860219 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8622227 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9620109 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21425144 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 15557515 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7513776 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31807987 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 23909286 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 21752462 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 23683727 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23107780 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 31081371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21836134 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21836134 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12871363 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 12871363 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10865409 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10865409 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10865409 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 1359619 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26831677 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 22721966 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 19670096 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 15141795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2778791 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2778791 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19749494 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19749494 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9156046 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 25142085 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20664198 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1706244 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6594926 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 15522049 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11990165 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18982860 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 8077767 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 8077767 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 25989827 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 25989827 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23799707 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21723606 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 16490616 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16490616 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1345803 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30120403 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 24083783 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21906708 — Biomarker: ACTG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACTG1; ACTG
Study 16005229 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 16005229 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 16005229 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 6130295 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25847819 — Biomarker: FANCE mRNA
Type: Predictive Biomarker (PRD)
Genes: FANCE; FACE
Study 21304215 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16681770 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 16681770 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 16681770 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 16681770 — Biomarker: HRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: HRAS; HRAS1
Study 16681770 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 16681770 — Biomarker: FGFR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 16681770 — Biomarker: CTSB mRNA
Type: Predictive Biomarker (PRD)
Genes: CTSB; CPSB
Study 16681770 — Biomarker: RPS6KB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RPS6KB1; STK14A
Study 16681770 — Biomarker: LAMC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMC2; LAMB2T; LAMNB2
Study 16681770 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 16681770 — Biomarker: PDGFRA mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 14975458 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 10345907 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30737835 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 21705068 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2949974 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 24943673 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8842608 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29478929 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 14583235 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 14583235 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 10890617 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 7602235 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 19955857 — Biomarker: LAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LAT
Study 3392240 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12553951 — Biomarker: LTB mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB; TNFC; TNFSF3
Study 10714908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9215540 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 26720025 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 26025097 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24750838 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 30672175 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 21189915 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15622265 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 2147405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17961204 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17961204 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17961204 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17961204 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9466468 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9466468 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 28824047 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18433528 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 16487219 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16487219 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9686072 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26465374 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 26465374 — Biomarker: NES mRNA
Type: Predictive Biomarker (PRD)
Genes: NES; Nbla00170
Study 21391876 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 18498540 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 11335776 — Biomarker: Serum hemoglobin A1C
Type: Surrogate Endpoint (SUR)
Study 9383177 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 31562608 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 26010524 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16098233 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 26502012 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 26066644 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17882235 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study 1595920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24870737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24071915 — Biomarker: OXTR mRNA
Type: Predictive Biomarker (PRD)
Genes: OXTR
Study 9879725 — Biomarker: MZB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MZB1; MEDA7; PACAP; HSPC190
Study 31351869 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 31351869 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31351869 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 11029607 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 11029607 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2828289 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 2828289 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 23036096 — Biomarker: NRF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRF1
Study 23036096 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21740798 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11710708 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 9385480 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9385480 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31342604 — Biomarker: PTK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTK2; FAK; FAK1
Study 22569992 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 22569992 — Biomarker: Ribonucleoside-diphosphate reductase large subunit
Type: Predictive Biomarker (PRD)
Genes: RRM1; RR1
Study 22569992 — Biomarker: RRM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RRM2; RR2
Study 22569992 — Biomarker: Solute carrier family 29 member 1
Type: Predictive Biomarker (PRD)
Genes: SLC29A1; ENT1
Study 10798765 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 22735431 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17366357 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28032333 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14601471 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14601471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15461606 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 2195579 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31418022 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 29351542 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16708735 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11689582 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 25688159 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25688159 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 25688159 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24308874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10499748 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10499748 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 10499748 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27578574 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 27578574 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 31444669 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 17886213 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11795349 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11795349 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11795349 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11795349 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18536698 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 10759443 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 30939537 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24534225 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 16900557 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11824858 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31187186 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 23676183 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 23676183 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10867972 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 8778949 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8778949 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 27315134 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 19853399 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10446037 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7796786 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30430745 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 24621834 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 17591024 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 28342988 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28342988 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28342988 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study 21749214 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 18246327 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 16524854 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24739073 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7936332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2678584 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 31519285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31519285 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31519285 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 20601207 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18049436 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 18049436 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 16215365 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 30951521 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 30951521 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15759021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25605660 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25605660 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23413981 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 17237444 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 17237444 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4