AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23401447 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18554591 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 30365009 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23429495 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21420063 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2817186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31004853 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26250495 — Biomarker: WBP2NL mRNA
Type: Predictive Biomarker (PRD)
Genes: WBP2NL; PAWP
Study 14512806 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 16645173 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 14652358 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24944128 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15914548 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 27548106 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 27548106 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 10026394 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 7473528 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 22380743 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 7678684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2889081 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 25579466 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 25579466 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 8811478 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 29532981 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29532981 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10356941 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21123766 — Biomarker: NPC1L1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NPC1L1
Study 21123766 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 21123766 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 21123766 — Biomarker: ABCG5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG5
Study 21123766 — Biomarker: ABCG8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG8
Study 19652945 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24199687 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 24199687 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21330809 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18712029 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 14513648 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 10371363 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 10371363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30712804 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30712804 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 17522509 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 15241630 — Biomarker: NMI mRNA
Type: Predictive Biomarker (PRD)
Genes: NMI
Study 18668226 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 9102590 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 25720808 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 15304576 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9762782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9762782 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 17917501 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 5763957 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26867199 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25711318 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7850232 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28711577 — Biomarker: DDC mRNA
Type: Predictive Biomarker (PRD)
Genes: DDC; AADC
Study 19468216 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2942062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28351962 — Biomarker: ADRB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB1; ADRB1R; B1AR
Study 15097300 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15097300 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11594571 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 7989456 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 2919093 — Biomarker: PRCP mRNA
Type: Predictive Biomarker (PRD)
Genes: PRCP; PCP
Study 30700344 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 27776372 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27776372 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10509160 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 10509160 — Biomarker: VEGFC mRNA
Type: Predictive Biomarker (PRD)
Genes: VEGFC
Study 10509160 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 10509160 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24767614 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22679718 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22679718 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22679718 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10352334 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 11296164 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 9311490 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2878745 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 28111428 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23967632 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 8884896 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 1414398 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 30045749 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 26295868 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 27372560 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24404797 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16462818 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 12478093 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 12478093 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 12478093 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10735889 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 10735889 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10735889 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8774551 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 30094725 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 30094725 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26228276 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25012934 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22528165 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18482525 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25108482 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 21960369 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 19838130 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 19838130 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16284465 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 25355722 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8643884 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 27177587 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 7774741 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2191071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2191071 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26285020 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24343092 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24343092 — Biomarker: FABP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FABP4
Study 24343092 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24343092 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19615730 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 9402612 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17573492 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17573492 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17573492 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16213352 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 30476217 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23437909 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 23437909 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21300674 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11199186 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18953082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6111438 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 9579771 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20507969 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 27835613 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19106767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17049767 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 15147428 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15147428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7759715 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30708350 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 29098244 — Biomarker: Vascular endothelial cadherin
Type: Safety Biomarker (SAF)
Genes: CDH5
Study 25935771 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 25935771 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2199148 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21997315 — Biomarker: ANKK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANKK1; PKK2; SGK288
Study 21997315 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 11693335 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9469525 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2907519 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28994705 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21692281 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 22922507 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22922507 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18678836 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 1846940 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 22128083 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15805203 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12578811 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 1748137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23321257 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 23321257 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 20872043 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 20872043 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 10945486 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 10945486 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24275841 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 14708413 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14708413 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 14708413 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 11236258 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 11236258 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 11236258 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 8640161 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 8640161 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20473991 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1817898 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28274246 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28274246 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23032742 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12226037 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9381718 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 3768492 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28988765 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30355323 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 12791430 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 7503006 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1820293 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31755915 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 31755915 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 25788320 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 23600363 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 19404617 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 16940077 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8379674 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 31356703 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 21875880 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21875880 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26522083 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 16186270 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23299714 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23299714 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 23299714 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23299714 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20606776 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 11134441 — Biomarker: HRC mRNA
Type: Predictive Biomarker (PRD)
Genes: HRC; HCP
Study 11134441 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11134441 — Biomarker: SNAP25 mRNA
Type: Predictive Biomarker (PRD)
Genes: SNAP25; SNAP
Study 31500854 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 28476766 — Biomarker: SLC25A20 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A20; CAC; CACT
Study 21270370 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 19697824 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8526836 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2487539 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31404668 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 21995887 — Biomarker: RHCE mRNA
Type: Predictive Biomarker (PRD)
Genes: RHCE; RHC; RHE
Study 11729513 — Biomarker: OTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 31079530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26387142 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26387142 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 26387142 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 26387142 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 26387142 — Biomarker: PDCD1LG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PDCD1LG2; B7DC; CD273; PDCD1L2; PDL2
Study 26387142 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 26387142 — Biomarker: CD8A mRNA
Type: Predictive Biomarker (PRD)
Genes: CD8A; MAL
Study 23942540 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 21673612 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 31077873 — Biomarker: CHRM3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRM3
Study 31077873 — Biomarker: IL2RB mRNA
Type: Predictive Biomarker (PRD)
Genes: IL2RB; IL15RB
Study 31077873 — Biomarker: KCNB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNB2
Study 31077873 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 31077873 — Biomarker: HTR3A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR3A; 5HT3R; HTR3
Study 31647774 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23301548 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 15349912 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10759446 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10759446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20197607 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20197607 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 16145640 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8194628 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31626156 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 23709583 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19704066 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)