AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 30888584 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23681940 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 20363843 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 20363843 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15778423 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 1781562 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31567988 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31567988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31567988 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27117175 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27117175 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24976416 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 24976416 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24976416 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21750118 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 19770669 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19770669 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12715373 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 18490173 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8967601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31477562 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 25158865 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 16311656 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12923641 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12225796 — Biomarker: THPO mRNA
Type: Predictive Biomarker (PRD)
Genes: THPO; MGDF
Study 20803425 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20803425 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 12610804 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12610804 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12610804 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19725009 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 11516807 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8314271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15583920 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 18235048 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18235048 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 12569298 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 12569298 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27401305 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27401305 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27401305 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24948653 — Biomarker: NRG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study 20450622 — Biomarker: ADAM17 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM17; CSVP; TACE
Study 18838525 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 1535568 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30118368 — Biomarker: AIP mRNA
Type: Predictive Biomarker (PRD)
Genes: AIP; XAP2
Study 9491438 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9491438 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 7877303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16721305 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25940537 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24007452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9344298 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8250653 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 26210489 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19548435 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 15529389 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28958437 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 28958437 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 17328944 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11715357 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8260367 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30946851 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 26299164 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 19554672 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 14982884 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 14982884 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 28569132 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 28569132 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 28569132 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 19923038 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 17461852 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12928045 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 12928045 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 9367461 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 9367461 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28783969 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 1533771 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25297613 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 11544433 — Biomarker: Alpha-glutathione S-transferase
Type: Safety Biomarker (SAF)
Study 9164520 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 3556051 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 1125653 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31784217 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 31784217 — Biomarker: CFTR
Type: Predictive Biomarker (PRD)
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 26711194 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11323501 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 27064499 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8214993 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8214993 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23672789 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23672789 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21732669 — Biomarker: 14-3-3 protein sigma
Type: Predictive Biomarker (PRD)
Genes: SFN; HME1
Study 19185634 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10217370 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7038316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31630358 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31630358 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18018769 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 16081875 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 9920144 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7501353 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 30683195 — Biomarker: Clusterin
Type: Safety Biomarker (SAF)
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 2205135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26485404 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 21422411 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23597479 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 23597479 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 10836723 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 9180622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8607407 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19397752 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 19397752 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17940111 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 17940111 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16513420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11544429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16888455 — Biomarker: AOX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AOX1; AO
Study 1432432 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3917900 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30053413 — Biomarker: HSPA1B mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA1B; HSP72
Study 30053413 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26060452 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 12108857 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1967210 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24055306 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 21865396 — Biomarker: MYO1G mRNA
Type: Predictive Biomarker (PRD)
Genes: MYO1G; HA2
Study 10620209 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6084121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31555926 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 20336066 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 10404912 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24495883 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21049628 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17877120 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 12121506 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 12121506 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 7539822 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7027062 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 7027062 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 31419239 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19246334 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11826546 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11826546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31990684 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25490907 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 25490907 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 16422971 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 11159876 — Biomarker: LGALSL mRNA
Type: Predictive Biomarker (PRD)
Genes: LGALSL; GRP; HSPC159
Study 11159876 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 25559146 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 23878024 — Biomarker: SLCO1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 20185386 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18185506 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 12714797 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 2294687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31401654 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 22704274 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22704274 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12479110 — Biomarker: GSS mRNA
Type: Predictive Biomarker (PRD)
Genes: GSS
Study 9667255 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 29247273 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 24955452 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 15888053 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24338935 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24338935 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23198694 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11136485 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9693995 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 7935635 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 29156056 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 17655947 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17655947 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21321426 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19761681 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19761681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10896408 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 26840887 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 18824996 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 12833584 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12833584 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10567194 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1818788 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27777219 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 24663014 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18805108 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30734418 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12809958 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12809958 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 11015339 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 9129860 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24756128 — Biomarker: DCC mRNA
Type: Predictive Biomarker (PRD)
Genes: DCC; IGDCC1
Study 29587582 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 25697852 — Biomarker: EMB mRNA
Type: Predictive Biomarker (PRD)
Genes: EMB
Study 20795383 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20795383 — Biomarker: CD72 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD72
Study 18421050 — Biomarker: ZFP36 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 2105795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30459073 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 30459073 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7266950 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18550472 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 16555496 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27854139 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 27130714 — Biomarker: 14-3-3 protein sigma
Type: Predictive Biomarker (PRD)
Genes: SFN; HME1
Study 27130714 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 24587320 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 24587320 — Biomarker: Vascular endothelial cadherin
Type: Safety Biomarker (SAF)
Genes: CDH5
Study 17034536 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 31707149 — Biomarker: PTGS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGS1; COX1
Study 31707149 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 16087795 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16087795 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16087795 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7742149 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6112844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10912758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9531185 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9531185 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28718527 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16960162 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15175800 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 7945491 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 7945491 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 3556129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30241488 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23643522 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23643522 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21336433 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30724455 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25943466 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25943466 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17729055 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17729055 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30285891 — Biomarker: ID1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ID1; BHLHB24; ID
Study 22440275 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22440275 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12890761 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 12890761 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 9004107 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6863470 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6863470 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2357865 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6274571 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8664019 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB