AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 21861845 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12073199 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9799972 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29172739 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29172739 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31405706 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31405706 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27721537 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 23024023 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 20304584 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20304584 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20304584 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 20304584 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 17627681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15954919 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 15954919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15954919 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15649112 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31898090 — Biomarker: PAG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAG1; CBP; PAG
Study 29893222 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18804362 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18989245 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 18989245 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31172717 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 31172717 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 8167489 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10827212 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 19372331 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16894336 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 6112039 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27842315 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21286719 — Biomarker: XRCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: XRCC2
Study 10521100 — Biomarker: CYP21A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP21A2; CYP21; CYP21B
Study 10521100 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 7595707 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 10971314 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3241272 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29189426 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26331290 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20941948 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 16298234 — Biomarker: NCAM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NCAM1; NCAM
Study 14750576 — Biomarker: NFIC mRNA
Type: Predictive Biomarker (PRD)
Genes: NFIC; NFI
Study 14750576 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 6802095 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 18779280 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 18779280 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 10075143 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6341684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30357394 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21041921 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15858063 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 7697926 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29653645 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 26609282 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 24023317 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 12741348 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 8835649 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3907725 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29106665 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 20508469 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8291920 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study 29467598 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29467598 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 23307840 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23307840 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23307840 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17070147 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17070147 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17070147 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 13677262 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 13677262 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27468128 — Biomarker: NR4A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR4A2; NOT; NURR1; TINUR
Study 19004053 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19004053 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19004053 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 6754331 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30217378 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26890031 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19063686 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19459233 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16758422 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3093918 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 30400122 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 30400122 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 31388683 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 31388683 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9842841 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9842841 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 9842841 — Biomarker: Th2 cell
Type: Safety Biomarker (SAF)
Study 25646328 — Biomarker: PNPLA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PNPLA3; ADPN; C22orf20
Study 14660479 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30412630 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 30412630 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study 30412630 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24895813 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 18414370 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15536472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8501148 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8501148 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31994022 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 18592146 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 18592146 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10922430 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8757514 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 17217710 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8349327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26964731 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22437412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18495838 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17302259 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10750762 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26323809 — Biomarker: SPN mRNA
Type: Predictive Biomarker (PRD)
Genes: SPN; CD43
Study 26323809 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26323809 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 12875064 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9124058 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27873388 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25421976 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14962687 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 14962687 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14962687 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9598253 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 3280493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24002278 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24002278 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30614406 — Biomarker: ATF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATF4; CREB2; TXREB
Study 30614406 — Biomarker: XBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: XBP1; TREB5; XBP2
Study 30614406 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 30614406 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 27456910 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 27456910 — Biomarker: PDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PDK4; PDHK4
Study 27456910 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27456910 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 9435408 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12142560 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8698787 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 19645851 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 23846872 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 10671847 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30597865 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 24253615 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 24253615 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1314260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23928836 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23928836 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23928836 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 10867543 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 10867543 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 10867543 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 9327192 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 27821114 — Biomarker: LTB4R mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 8772558 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 26791606 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 9576151 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28259610 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 28259610 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 28259610 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 24481570 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22104618 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 19577277 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 27095167 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26775373 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14740953 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 10674459 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2645914 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26089546 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9112894 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31784345 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29631782 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16224525 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12005077 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 12005077 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10068928 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 10068928 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 20857170 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17434599 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17434599 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7938398 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7938398 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7938398 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 27267081 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 18063394 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 15910557 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10473054 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 2667865 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 30765033 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 25799356 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24195548 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9869105 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 25692251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7594512 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7594512 — Biomarker: Macrophage inflammatory protein 1-alpha
Type: Monitoring Biomarker (MOI)
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 2299797 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2299797 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 28803925 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 29048238 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25394438 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15460215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9161933 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 27605403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8675938 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 1801057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25124998 — Biomarker: miR-652
Type: Safety Biomarker (SAF)
Genes: MIR652
Study 25124998 — Biomarker: miR-103
Type: Safety Biomarker (SAF)
Study 17546496 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11772148 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11772148 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11772148 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 7948822 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27873046 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 27873046 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26934167 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26934167 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 24376273 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 8582132 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31407967 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 31407967 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 11447496 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30948215 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 23787721 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29171486 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 23273292 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 16565627 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8617132 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 1418064 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1418064 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 17535971 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 17535971 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7363678 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31275980 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15522364 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 9213204 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20515959 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17092412 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 31197507 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 31197507 — Biomarker: MYD88 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYD88
Study 31197507 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31197507 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 15974350 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31552704 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31552704 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31501887 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24451954 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24451954 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24451954 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)