AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 20462428 — Biomarker: PDXP mRNA
Type: Predictive Biomarker (PRD)
Genes: PDXP; CIN; PLP; PLPP
Study 7492487 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31101323 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28588686 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 18162932 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26995281 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10639654 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 15681523 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31694684 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 19833260 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 19833260 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 19833260 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 19833260 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 24247300 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 10972608 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8725722 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 22219405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24906857 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19296044 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 19296044 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11575527 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26939320 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16859530 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 26669226 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26669226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1417537 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 1417537 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27348249 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 24824118 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 20188583 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15926717 — Biomarker: CA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA4
Study 9699932 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 7877158 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3266005 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 28818054 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21384334 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16616012 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30735532 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30805363 — Biomarker: PRF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRF1; PFP
Study 26053030 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24653917 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 9029748 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 30461315 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 25825393 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 23649189 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 21411446 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 14981107 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 811982 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30896608 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24944260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15379738 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 20024753 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17058023 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14567822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6794420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26401704 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 21152932 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 23573836 — Biomarker: SPRR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPRR3; SPRC
Study 21740240 — Biomarker: STIL mRNA
Type: Predictive Biomarker (PRD)
Genes: STIL; SIL
Study 21740240 — Biomarker: PSMB7 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSMB7; Z
Study 30630559 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30630559 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28667118 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 21739686 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 8482557 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 8482557 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 28882161 — Biomarker: EEF1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EEF1A2; EEF1AL; STN
Study 26333545 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19080431 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2659003 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 30325764 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19419254 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17907081 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15198380 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9554677 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20467943 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10404769 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1535580 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 1535580 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 17989110 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 16301267 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 16928616 — Biomarker: GAPDH mRNA
Type: Predictive Biomarker (PRD)
Genes: GAPDH; GAPD; CDABP0047; OK/SW-cl.12
Study 27917793 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 19958442 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 19958442 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 15756156 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12479634 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 31816191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26071656 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23953030 — Biomarker: MRP2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ABCC2; DJS; cMRP
Study 23953030 — Biomarker: ABCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 23953030 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 18344568 — Biomarker: FIP1L1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FIP1L1; FIP1; RHE
Study 18344568 — Biomarker: PDGFRA mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 18344568 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 7960021 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26519345 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23686706 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 3046824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26705299 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25636071 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 23690420 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 16884341 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16884341 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 11073858 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 22466349 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 31711059 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 22363556 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 22363556 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22363556 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 22363556 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 24602579 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 17398191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10451039 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10451039 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28652463 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28652463 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23081732 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 23081732 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9159629 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 8205297 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8205297 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3581681 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27601237 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24709304 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 25850440 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22647618 — Biomarker: PDXP mRNA
Type: Predictive Biomarker (PRD)
Genes: PDXP; CIN; PLP; PLPP
Study 31928229 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 23949801 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16142502 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14727367 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 11527612 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 8420344 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8420344 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31230147 — Biomarker: Bacteroides intestinalis
Type: Safety Biomarker (SAF)
Study 16618270 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10707514 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28070639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30645840 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 20501774 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30448598 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 30448598 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21863389 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 21863389 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16538011 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 18239197 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 7224205 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31567872 — Biomarker: FADS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS1; FADSD5
Study 31567872 — Biomarker: FADS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS2
Study 27839807 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21416238 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15028129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28325823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10971099 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8877910 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 6378450 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29239764 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 25341118 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14644697 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6397454 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23018304 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15542577 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6326562 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6326562 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6326562 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 30647402 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30647402 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12466782 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7844610 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29117276 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8040900 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31461123 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28396303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26134386 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9766255 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 3041874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3041874 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 12820059 — Biomarker: Th2 cell
Type: Safety Biomarker (SAF)
Study 29074041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21401729 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18544983 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 21546099 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 21546099 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 18308653 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8821108 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 1951474 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1951474 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6119096 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17183623 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 21300933 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 3752464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31043093 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 9122553 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 27523719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24158227 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 22999073 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 22999073 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 10540091 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30448193 — Biomarker: SPN mRNA
Type: Predictive Biomarker (PRD)
Genes: SPN; CD43
Study 30448193 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22546988 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22546988 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19616668 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8200552 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 20978528 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20978528 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18718556 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12965979 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12965979 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12965979 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23914920 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23914920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21859656 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18257271 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31605797 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31605797 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 26980210 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22770758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17662090 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 16380708 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 29945245 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 29782217 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 29782217 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 26556577 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 26556577 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 26547499 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 21778673 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11268223 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11268223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16626957 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25475929 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17135618 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12706934 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12706934 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 24491572 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 24491572 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 11704445 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9627365 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9627365 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3287837 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 31166679 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 31166679 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31166679 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 16476114 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16476114 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30585985 — Biomarker: DMA mRNA
Type: Predictive Biomarker (PRD)
Genes: DMA; HLA-DMA; hCG_2001572
Study 25891697 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20964740 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20964740 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12034517 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 12034517 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)