AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 18036365 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18036365 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31433518 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6387059 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 6387059 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 30523756 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30523756 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23157899 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 17622289 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17622289 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17622289 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11849412 — Biomarker: THBS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: THBS1; TSP; TSP1
Study 11849412 — Biomarker: FBN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBN1; FBN
Study 14759615 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27136912 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 27136912 — Biomarker: JAK2
Type: Predictive Biomarker (PRD)
Genes: JTK10
Study 9186240 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 15932840 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 9523857 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31448392 — Biomarker: GSS mRNA
Type: Predictive Biomarker (PRD)
Genes: GSS
Study 23730848 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 23963438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23963438 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20672447 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 17933470 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17933470 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 17933470 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 7477217 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31260548 — Biomarker: CARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARS1; CARS
Study 15110370 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15110370 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19543664 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 15611462 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 11321866 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8512162 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27871598 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24829298 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 24829298 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20538738 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8005121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2511239 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 23333201 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21666065 — Biomarker: UGT2B15 mRNA
Type: Predictive Biomarker (PRD)
Genes: UGT2B15; UGT2B8
Study 16551910 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 15142871 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1395119 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1395119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29138181 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 22179955 — Biomarker: PPARG mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARG; NR1C3
Study 22179955 — Biomarker: LYPLAL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LYPLAL1
Study 22179955 — Biomarker: GNPDA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNPDA2; GNP2
Study 22179955 — Biomarker: NEGR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NEGR1; IGLON4; UNQ2433/PRO4993
Study 22179955 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 22179955 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 16087822 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17997890 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17997890 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9633944 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 26226139 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 26226139 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9207344 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 3415398 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12152004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7912878 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31504336 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31504336 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28832978 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28832978 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16810760 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10707786 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 24452810 — Biomarker: CTRC mRNA
Type: Predictive Biomarker (PRD)
Genes: CTRC; CLCR
Study 16286578 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16286578 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10490723 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 24355210 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24355210 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24355210 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21371166 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17874530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9223108 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9223108 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 21908036 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 21908036 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21908036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10516413 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2248921 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 25489056 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10407503 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28849773 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25670366 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 25670366 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17376293 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17376293 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17376293 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15199325 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20639391 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7032533 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 31932201 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 20446847 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20446847 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9197875 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9197875 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9197875 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 23611825 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11095136 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 30909333 — Biomarker: WWTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WWTR1; TAZ
Study 21300083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19583067 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 19583067 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17456491 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 8079827 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25732417 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 25732417 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19067726 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19067726 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 19067726 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19067726 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15142013 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3279725 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23406684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17581217 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17581217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15699266 — Biomarker: ACAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAT1; ACAT; MAT
Study 15699266 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2272957 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16691061 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 11350571 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29091530 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23759461 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12563672 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 10100069 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9156926 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 14973308 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 7946592 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 2840000 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28940037 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 12388895 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 6237051 — Biomarker: INSM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: INSM1; IA1
Study 26048144 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25182544 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24445367 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15062908 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 28703374 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10866899 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10866899 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1530680 — Biomarker: ACKR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACKR1; DARC; FY; GPD
Study 23743487 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 18063490 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8603758 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 31714353 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30366971 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30366971 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30366971 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27183835 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 24840045 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18695931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10805546 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10805546 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10805546 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 10805546 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 2353864 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2353864 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31558739 — Biomarker: EED mRNA
Type: Predictive Biomarker (PRD)
Genes: EED
Study 27485237 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 15649287 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 8207741 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16569546 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 16569546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9071201 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8369985 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3505530 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17012105 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12952774 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8227469 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26668251 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study 22911148 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 17359400 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 15182266 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 9675624 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9675624 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 21566425 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11789281 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 11789281 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 11789281 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 26661319 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21439633 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27172483 — Biomarker: MAP2K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K1; MEK1; PRKMK1
Study 27172483 — Biomarker: MAP2K2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K2; MEK2; MKK2; PRKMK2
Study 25436769 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8770319 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25230866 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 24802654 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 7890059 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28439893 — Biomarker: CR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR2; C3DR
Study 28439893 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 23972450 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 15308881 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15308881 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7406949 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 30296404 — Biomarker: CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR1; C3BR
Study 30296404 — Biomarker: CR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR2; C3DR
Study 28432376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24862330 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 6407293 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11435967 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9740480 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9740480 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2854116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23536132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12584828 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10405773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6249334 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15521893 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26095263 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26095263 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11287757 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 2122024 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25263393 — Biomarker: SLCO1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 19464401 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16518320 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 10910024 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28985263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17823963 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16648613 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9525349 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29703223 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 27598802 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22098260 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 22098260 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 17611249 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9790077 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 30610443 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28074795 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 22814896 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 15262189 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 24378381 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12595861 — Biomarker: DUSP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DUSP2; PAC1
Study 16213288 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 27405619 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 23652489 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 23652489 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11455733 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 2899140 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28830404 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28830404 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28830404 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25503447 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21368422 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH