AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT03117634 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02709993 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT02709993 — Biomarker: TAPBP mRNA
Type: Predictive Biomarker (PRD)
Genes: TAPBP; NGS17; TAPA
Study NCT00315224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03551847 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT02102893 — Biomarker: SSTR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SSTR2
Study NCT02102893 — Biomarker: SSTR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SSTR5
Study NCT02615847 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02472366 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03898622 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study NCT01171872 — Biomarker: ACAD8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAD8; ARC42; IBD
Study NCT03522246 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT01838174 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00827996 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00128661 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study NCT00404027 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04202497 — Biomarker: KDM1A mRNA
Type: Predictive Biomarker (PRD)
Genes: KDM1A; AOF2; KDM1; KIAA0601; LSD1
Study NCT01518569 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT01518569 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02979327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00582465 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03338374 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03925974 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04010344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02419937 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02419937 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT04444557 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT01813006 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study NCT04879888 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study NCT03379103 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT03011294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02453282 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02453282 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT02453282 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00923013 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study NCT03524274 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study NCT04253340 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT04019561 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study NCT03275818 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study NCT01998672 — Biomarker: NR1H4 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT00721747 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02722980 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03000296 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT04426669 — Biomarker: CISH mRNA
Type: Predictive Biomarker (PRD)
Genes: CISH; G18
Study NCT02660333 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04355104 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study NCT00546897 — Biomarker: Chromosome 5q
Type: Predictive Biomarker (PRD)
Study NCT00380445 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT01275586 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study NCT02924883 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00445003 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00445003 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT01987011 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT03367754 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT03455348 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04636697 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT01270763 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01985893 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04681703 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02713022 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02109354 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT03564561 — Biomarker: Lysosomal alpha-glucosidase
Type: Safety Biomarker (SAF)
Genes: GAA
Study NCT04758260 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study NCT00406068 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study NCT03084822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04300673 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04135027 — Biomarker: CTLA4
Type: Predictive Biomarker (PRD)
Genes: CD152; CD; GSE; CTLA-4
Study NCT01198743 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT01198743 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study NCT01198743 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study NCT01198743 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study NCT01198743 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study NCT01094067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04165239 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT04165239 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT02945826 — Biomarker: Urokinase plasminogen activator surface receptor
Type: Monitoring Biomarker (MOI)
Genes: PLAUR; MO3; UPAR
Study NCT02276963 — Biomarker: AQP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP4
Study NCT03827044 — Biomarker: POLE mRNA
Type: Predictive Biomarker (PRD)
Genes: POLE; POLE1
Study NCT03214991 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study NCT03717350 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study NCT03717350 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03482427 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00924326 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT05939518 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT02698982 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03049826 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study NCT03923465 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study NCT04334174 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study NCT02023853 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study NCT00535951 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study NCT01646788 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT01381705 — Biomarker: FCGR3A mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study NCT01237522 — Biomarker: SLC22A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A2; OCT2
Study NCT02566330 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00885456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04385771 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT00496548 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03408119 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03064113 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT05733884 — Biomarker: AXL mRNA
Type: Predictive Biomarker (PRD)
Genes: AXL; UFO
Study NCT02107092 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study NCT01414972 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04132908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03099174 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03099174 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT04068441 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04086888 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04258150 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT02414152 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study NCT03983486 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study NCT03983486 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study NCT03983486 — Biomarker: CDKN2C mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2C; CDKN6
Study NCT03983486 — Biomarker: CKS1B mRNA
Type: Predictive Biomarker (PRD)
Genes: CKS1B; CKS1; PNAS-143; PNAS-16
Study NCT02247752 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT00301366 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT02424266 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study NCT02126137 — Biomarker: NPC1L1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NPC1L1
Study NCT02647164 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study NCT03089476 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study NCT00095212 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02609295 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT01886326 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04795154 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02616809 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02047071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03929900 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT00297648 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01008878 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02683083 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00517530 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT03124303 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04353557 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study NCT01606540 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02479893 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study NCT04517162 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00624065 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03185039 — Biomarker: MMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP2; CLG4A
Study NCT03185039 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study NCT01804777 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01460147 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00195260 — Biomarker: SKI mRNA
Type: Predictive Biomarker (PRD)
Genes: SKI
Study NCT04109417 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01753895 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03991260 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00972959 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00736970 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05088005 — Biomarker: Growth/differentiation factor 15
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study NCT05088005 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study NCT03918486 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02242123 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study NCT04527575 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT04544787 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT00344110 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02259270 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT01590108 — Biomarker: APLNR mRNA
Type: Predictive Biomarker (PRD)
Genes: APLNR; AGTRL1; APJ
Study NCT01537861 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT04299594 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00890981 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03211403 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study NCT01555411 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT03018834 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT00076037 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT04154579 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00333489 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00547781 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study NCT03636763 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT05908864 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03204539 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study NCT03026348 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT00978822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02791880 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT00339547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04192006 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04192006 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT04192006 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study NCT04192006 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04192006 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT04192006 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study NCT04192006 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study NCT01482377 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study NCT01900080 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT02647580 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study NCT00617305 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study NCT00617305 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study NCT00868374 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study NCT01971619 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT04328337 — Biomarker: SLC2A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A1; GLUT1
Study NCT02007031 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03182114 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03149653 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03648658 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study NCT03659006 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study NCT00724477 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02511782 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study NCT05345236 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT01313273 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT03760848 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT03518905 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study NCT04008498 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01930227 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01956786 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03824119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00001862 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01108094 — Biomarker: Zinc finger protein GLI1
Type: Predictive Biomarker (PRD)
Genes: GLI1; GLI
Study NCT01954394 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04294979 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study NCT00002804 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01081613 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01081613 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT03533998 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT04863768 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT00550563 — Biomarker: CYP24A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP24A1; CYP24
Study NCT03352089 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study NCT01586611 — Biomarker: Solute carrier family 29 member 1
Type: Predictive Biomarker (PRD)
Genes: SLC29A1; ENT1
Study NCT00594685 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study NCT02115100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00286754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02052947 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04821401 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01587729 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01139320 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study NCT03089372 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study NCT03443596 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00162474 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study NCT00949585 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study NCT03475030 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04622566 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study NCT03830268 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT02575222 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00550537 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1