AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 8936895 — Biomarker: LAX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAX1; LAX
Study 8936895 — Biomarker: SLC22A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A4; ETT; OCTN1; UT2H
Study 8936895 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 30092157 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2650730 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23663287 — Biomarker: PPP6R3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPP6R3; C11orf23; KIAA1558; PP6R3; SAPL; SAPS3
Study 15652899 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 21756276 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 21756276 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 16995327 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 29390298 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19549431 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 22305830 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18222389 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18222389 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 18222389 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 18222389 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 24964348 — Biomarker: PTGDR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 24964348 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 17311061 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17311061 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30324895 — Biomarker: TNFRSF1B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1B; TNFBR; TNFR2
Study 30324895 — Biomarker: TNFRSF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1A; TNFAR; TNFR1
Study 30324895 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31682574 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15169694 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 25246569 — Biomarker: CA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA3
Study 22211956 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 30816331 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 26077176 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 24717838 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 20643186 — Biomarker: SLC10A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC10A3; DXS253E; P3
Study 17013636 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25826741 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23404145 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 21830407 — Biomarker: ADAM17 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM17; CSVP; TACE
Study 19286361 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7611178 — Biomarker: PSMB6 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSMB6; LMPY; Y
Study 29332743 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 27348762 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26756390 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 16605566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9802528 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 22362401 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 14725610 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 14725610 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11774270 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9419169 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27558280 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15494274 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 24895810 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 20543666 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15900355 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12611560 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 8897030 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8897030 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 26573456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16367882 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12635001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23178916 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31325962 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 27548249 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 27548249 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10732589 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8023589 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8023589 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8023589 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 29211509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10357120 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study 30683945 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 19169684 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 7896423 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 30187612 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18042476 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8389269 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8389269 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 18323476 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 29907082 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22317271 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 18226045 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18226045 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8703452 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31201218 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22935482 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18496484 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18496484 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 18496484 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29843500 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29843500 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23816960 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23816960 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16352489 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 16352489 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19477358 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 19477358 — Biomarker: ADIPOQ mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 15014819 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 328328 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19805640 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22994061 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22994061 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16167938 — Biomarker: FGR mRNA
Type: Predictive Biomarker (PRD)
Genes: FGR; SRC2
Study 18317392 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 11995347 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 27178566 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27178566 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 27178566 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21648052 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20165744 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 18062519 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12068252 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 23943299 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 18985146 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9243107 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8500516 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 12638028 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 12638028 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 23834479 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 19522023 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 19522023 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 3207528 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22048557 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28028076 — Biomarker: FNDC5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FNDC5; FRCP2
Study 12577354 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 1426320 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 6320627 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6320627 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29869538 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 29971527 — Biomarker: PNPLA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PNPLA3; ADPN; C22orf20
Study 29971527 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 25218552 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 8695248 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 26708006 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18095238 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18095238 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18095238 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8832493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29507938 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27764725 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 25241758 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 20491843 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18025765 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 2330929 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 30810700 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 28151412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24299607 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 12954578 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 8441838 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23796946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23796946 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 20724426 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9329413 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 29362512 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 29362512 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 29362512 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 29362512 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 29362512 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 29241617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7798165 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30096258 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 30096258 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30096258 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 20861820 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 20861820 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 20861820 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 10511327 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7865226 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7865226 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25881455 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25881455 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25881455 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25881455 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 25881455 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 15656877 — Biomarker: LIPC mRNA
Type: Predictive Biomarker (PRD)
Genes: LIPC; HTGL
Study 15656877 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7530507 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7530507 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7530507 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 24621065 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 24621065 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 23909679 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23909679 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21792626 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21792626 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 21792626 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 21792626 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 3625417 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 18375318 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15262194 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24336330 — Biomarker: TGFBR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TGFBR2
Study 24336330 — Biomarker: Mothers against decapentaplegic homolog 2
Type: Predictive Biomarker (PRD)
Genes: SMAD2; MADH2; MADR2
Study 9209998 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 23052111 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12659243 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 21999668 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 27716125 — Biomarker: DARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DARS1; DARS; PIG40
Study 16208152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26713333 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26713333 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 26713333 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25205864 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 25205864 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 25205864 — Biomarker: TRIB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIB1; C8FW; GIG2; TRB1
Study 25205864 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 20628384 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 8788597 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 1345050 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17973865 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11502777 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11502777 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 9266258 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9266258 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9266258 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7508066 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7508066 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 31976548 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 28887192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11369660 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 8282621 — Biomarker: Interleukin 1 alpha
Type: Safety Biomarker (SAF)
Genes: IL1A; IL1F1
Study 8282621 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18199590 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9239992 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 23248072 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 12670781 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8776642 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 8776642 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 8776642 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 8776642 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 20980923 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28222742 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 16032784 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2454361 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27046472 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 25525981 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 25525981 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 20420579 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15625365 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27050538 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 22353022 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22353022 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19965682 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 16282540 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH