AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 11762413 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 11762413 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study 11762413 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 11762413 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7892952 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study 7892952 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 3364800 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3364800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3364800 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 23023841 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23023841 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8597678 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8597678 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8597678 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9594050 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28582812 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 28582812 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 11447364 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11447364 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25048955 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23013352 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19945816 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10430713 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 7556961 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1934686 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 14981335 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 14981335 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 444345 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 29547835 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26803690 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 26803690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7297145 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20864946 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23403945 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 23403945 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 23403945 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17124283 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29151034 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9097890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29044496 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11199194 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1629748 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27941065 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 27941065 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25943660 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 16115972 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30892782 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 15860521 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10461471 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 7828381 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21463065 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 8559491 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31112379 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21943940 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27447966 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 17951945 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17951945 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16208150 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2273081 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27719707 — Biomarker: SFRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SFRP1; FRP; FRP1; SARP2
Study 22894553 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12517686 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10648307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25199121 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 19935757 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 19935757 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 809253 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 30961412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25307195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15154946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8446039 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8446039 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3716914 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22555227 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22555227 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18605811 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30966821 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12036483 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7579054 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 25297344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8888359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26267328 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21962066 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 18469235 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2895705 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28623414 — Biomarker: LHB mRNA
Type: Predictive Biomarker (PRD)
Genes: LHB
Study 25899452 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20038723 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20038723 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 17869973 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10065682 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10065682 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8828358 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2866097 — Biomarker: NAPA mRNA
Type: Predictive Biomarker (PRD)
Genes: NAPA; SNAPA
Study 29327047 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29327047 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 29327047 — Biomarker: Arginase-1
Type: Safety Biomarker (SAF)
Genes: ARG1
Study 25285367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22689317 — Biomarker: S100A12 mRNA
Type: Predictive Biomarker (PRD)
Genes: S100A12
Study 22689317 — Biomarker: ATP-binding cassette sub-family C member 11
Type: Predictive Biomarker (PRD)
Genes: ABCC11; MRP8
Study 22689317 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16283275 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 30278429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30278429 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30278429 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30278429 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11966868 — Biomarker: LAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LAT
Study 11966868 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 7772357 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24146762 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18400322 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 6469823 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30032504 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12030736 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9972670 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 31068018 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28974570 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28974570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21193696 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 12559215 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 12559215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8446138 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29898035 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 18633420 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16849118 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12770975 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 12770975 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 9601864 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8224265 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 3896278 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26642810 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26642810 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 24690511 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 18591457 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17021318 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 14618246 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 30304108 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16168278 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12514662 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10536645 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2054272 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30716803 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 11590993 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 25792076 — Biomarker: TYMS
Type: Predictive Biomarker (PRD)
Genes: Tsase; TMS; HsT422
Study 18070967 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 8900980 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11023140 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27385662 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14602790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12454840 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 24797321 — Biomarker: ADH1B mRNA
Type: Predictive Biomarker (PRD)
Genes: ADH1B; ADH2
Study 24797321 — Biomarker: ALDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH2; ALDM
Study 31321514 — Biomarker: METTL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: METTL1; C12orf1
Study 31321514 — Biomarker: DDR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 31321514 — Biomarker: MICB mRNA
Type: Predictive Biomarker (PRD)
Genes: MICB; PERB11.2
Study 31321514 — Biomarker: GZMA mRNA
Type: Predictive Biomarker (PRD)
Genes: GZMA; CTLA3; HFSP
Study 28647451 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21528593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19447837 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 14722028 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14722028 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27354202 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 24370801 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 18480832 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10559510 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10559510 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29801398 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 29801398 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 26231884 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 196232 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 26059012 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 23852309 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 7511740 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7511740 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7511740 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11392066 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 1325613 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6381612 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 23819476 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12695287 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 9893077 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7751429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31355456 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31355456 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 31355456 — Biomarker: TNFSF13 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 31355456 — Biomarker: CAMLG mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMLG; CAML; GET2
Study 9503547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9503547 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9175947 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20167430 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 16494640 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15347114 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8006520 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20821047 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8422814 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8643419 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2145770 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2145770 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31437853 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27526332 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 26118144 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10737537 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 1332634 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1332634 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12956739 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9354313 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 30237219 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 18055982 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 16581423 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 16581423 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11556039 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 8669669 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 29956886 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 20222114 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15812629 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 15812629 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15812629 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1941406 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 30929097 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 30929097 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 23279139 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 17065639 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12899797 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 2856773 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2856773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14679274 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 25908462 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23417664 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 19541717 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 19541717 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 19541717 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11728145 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24857251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24857251 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15797646 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15797646 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15797646 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15797646 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 15797646 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 30156654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26813471 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26813471 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20352259 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27236888 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 27236888 — Biomarker: ATG12 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATG12; APG12; APG12L
Study 27236888 — Biomarker: ATG13 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATG13; KIAA0652
Study 27236888 — Biomarker: ATG5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATG5; APG5L; ASP
Study 22493419 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8087191 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2676440 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19701600 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 19701600 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 19701600 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)