AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 27206212 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27206212 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27206212 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8425237 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2949584 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15736108 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15736108 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9014745 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31322914 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25403211 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 25403211 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 15097246 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12234947 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9652433 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 28740125 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 28740125 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29244111 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29244111 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20530280 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16189633 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 16189633 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 10955749 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 15999421 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 12198664 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 25961767 — Biomarker: CXADR mRNA
Type: Predictive Biomarker (PRD)
Genes: CXADR; CAR
Study 24001627 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15025555 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 11903420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11903420 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9577377 — Biomarker: HFE mRNA
Type: Predictive Biomarker (PRD)
Genes: HFE; HLAH
Study 7944471 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28840750 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 2685958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2685958 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29277060 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 29277060 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 2428885 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 27039845 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 27039845 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27039845 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 27039845 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20644331 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 20644331 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9925837 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2106735 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 2106735 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 25469673 — Biomarker: Platelet-derived growth factor B
Type: Pharmacodynamic Biomarker (PDY)
Genes: PDGFB; PDGF2; SIS
Study 12874818 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 1443738 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3001563 — Biomarker: C1QL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 3001563 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30806083 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 25860002 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 19858237 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11534565 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11534565 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3396267 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 25908311 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8355436 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 28199464 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26224879 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 6107932 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 30075569 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23782581 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25646296 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1406395 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1406395 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 30172724 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 30172724 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 10464834 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27444687 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12077767 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12077767 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 29103081 — Biomarker: PDE10A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE10A
Study 23803951 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21254911 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21254911 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21254911 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23691825 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 19486260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30554783 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 20561917 — Biomarker: WWTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WWTR1; TAZ
Study 17605234 — Biomarker: FMN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMN1; FMN; LD
Study 17605234 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 10594528 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 7491848 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29475928 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19131173 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 16459721 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 16459721 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16459721 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 8935444 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study 4082879 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30932181 — Biomarker: AQP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP4
Study 30172759 — Biomarker: TK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TK1
Study 26563287 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 22496085 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 12235692 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19221759 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 19221759 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 19221759 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17056241 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 28424258 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14700552 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 14700552 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15025402 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 31667542 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24487458 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 23457130 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23457130 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15307697 — Biomarker: CFL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CFL1; CFL
Study 18272916 — Biomarker: CDKN1B mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN1B; KIP1; p27
Study 18272916 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18272916 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 12657408 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 1542853 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 30673744 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25189856 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 7946898 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 23559149 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 14675411 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 28603135 — Biomarker: ABCD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCD2; ALD1; ALDL1; ALDR; ALDRP
Study 23095282 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11988132 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9808143 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 9808143 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28075228 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 14576659 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28606184 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18822903 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 18822903 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 18822903 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9015908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6738365 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19055987 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 11300450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9278210 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 18410888 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18410888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16190386 — Biomarker: CPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPB1; CPB; PCPB
Study 28283863 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18480522 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12051399 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12051399 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12051399 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 1706023 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31556937 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30024861 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24048909 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 20158297 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22118842 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22118842 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22118842 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 22118842 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31815678 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17664472 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17664472 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 7865648 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 31738351 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8436090 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 26739253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17140611 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 10195630 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1734985 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24085591 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 14628252 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14628252 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10737282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10199756 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29884405 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 11641743 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 11641743 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7850531 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24708775 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23125943 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16048482 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 16048482 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 16048482 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31838585 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28407999 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21454244 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 15210738 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 10450749 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 793849 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 793849 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 793849 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 28068788 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 8543958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2472488 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 2472488 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 26602296 — Biomarker: EED mRNA
Type: Predictive Biomarker (PRD)
Genes: EED
Study 21823420 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21823420 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 23801357 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 1548516 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 7148735 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 28248887 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28248887 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26546068 — Biomarker: ID1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ID1; BHLHB24; ID
Study 371903 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18847329 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17118687 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31033362 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31033362 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31033362 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18665163 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 1667511 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 6406649 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26858433 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 12390715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9932994 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25864745 — Biomarker: Anti-thyroid autoantibody
Type: Safety Biomarker (SAF)
Study 15298427 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29209951 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 10661604 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2312764 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21211642 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 18032935 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2905341 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2905341 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28234152 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 23965491 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 18487568 — Biomarker: FGF7 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF7; KGF
Study 16947782 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16947782 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16947782 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27101297 — Biomarker: miR-133a
Type: Safety Biomarker (SAF)
Study 26153084 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 26153084 — Biomarker: ANKK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANKK1; PKK2; SGK288
Study 26153084 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 3034038 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26040438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11251132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30237264 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 19917453 — Biomarker: ABCG5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG5
Study 19917453 — Biomarker: ABCG8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG8
Study 19917453 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 31363810 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21829106 — Biomarker: MT2A mRNA
Type: Predictive Biomarker (PRD)
Genes: MT2A; CES1; MT2
Study 16060253 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 15023669 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1