AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 9257203 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7647223 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 7647223 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 31283365 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31283365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24451696 — Biomarker: MEA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MEA1; MEA
Study 21526889 — Biomarker: DNAAF11 mRNA
Type: Predictive Biomarker (PRD)
Genes: DNAAF11; LRRC6; LRTP; TSLRP
Study 7504387 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 26792419 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8881952 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 24861192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20550533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16390890 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21668387 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19192976 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16723303 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15523323 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18077795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18077795 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1901199 — Biomarker: PSMB7 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSMB7; Z
Study 31532574 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 23805813 — Biomarker: PTGER3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGER3
Study 24286456 — Biomarker: CCR3 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CCR3; CMKBR3
Study 24286456 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 15992231 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12790212 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 8181027 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21054767 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 21054767 — Biomarker: FST mRNA
Type: Predictive Biomarker (PRD)
Genes: FST
Study 17120180 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9632123 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 28889724 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 22011432 — Biomarker: T-cell specific protein RANTES
Type: Safety Biomarker (SAF)
Genes: CCL5; D17S136E; SCYA5
Study 8772586 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 8772586 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23203358 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21047406 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21903907 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16792136 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 1729064 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20876405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20876405 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8722438 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8722438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1723447 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25017924 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25017924 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 25017924 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15272511 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 11603386 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 25564143 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25564143 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25564143 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21856767 — Biomarker: DKK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DKK1; UNQ492/PRO1008
Study 21856767 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19726374 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 15487709 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15487709 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 29659967 — Biomarker: RGR mRNA
Type: Predictive Biomarker (PRD)
Genes: RGR
Study 16971666 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 16971666 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 27903341 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24990091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22048884 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12716662 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 12716662 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12716662 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30202873 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 25765835 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25765835 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25159238 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25159238 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11570639 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 23025273 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21403548 — Biomarker: TIFA mRNA
Type: Predictive Biomarker (PRD)
Genes: TIFA; T2BP
Study 21403548 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 16802483 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3519058 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 24843115 — Biomarker: CPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPB1; CPB; PCPB
Study 24843115 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 18637601 — Biomarker: Serum methemoglobin
Type: Surrogate Endpoint (SUR)
Study 16567825 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 12592052 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8166055 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29536284 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23980734 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18199920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12750250 — Biomarker: NOCT mRNA
Type: Predictive Biomarker (PRD)
Genes: NOCT; CCR4; CCRN4L; NOC
Study 10893688 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31517759 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 17216681 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9562222 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 30660443 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 21870317 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 12227482 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 2644531 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 7890006 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 7890006 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 7656926 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 351570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25542416 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23884017 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 29183347 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 14990633 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 7539182 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 336306 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30820962 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 27326658 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27326658 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 14621837 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22303706 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9294121 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 3011530 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23117133 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 23117133 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15902990 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 15155715 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 28145413 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 21054216 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11506058 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11506058 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 30545915 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 30545915 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30545915 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25702095 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25639139 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31001997 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 24352294 — Biomarker: TEF mRNA
Type: Predictive Biomarker (PRD)
Genes: TEF; KIAA1655
Study 21195592 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11923036 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 11923036 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26529006 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20689328 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 20689328 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 20689328 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 19801040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15644572 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3038722 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 29717197 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 29717197 — Biomarker: KLB mRNA
Type: Predictive Biomarker (PRD)
Genes: KLB
Study 29717197 — Biomarker: FGFR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR4; JTK2; TKF
Study 16008071 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 2288833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14675406 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 14675406 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31638433 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 31638433 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24000874 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17081832 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17081832 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19942303 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19942303 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 19942303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19629514 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 9738637 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2856543 — Biomarker: TAC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAC1; NKA; NKNA; TAC2
Study 23546631 — Biomarker: PCSK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK5; PC5; PC6
Study 12794835 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12794835 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24281981 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18478481 — Biomarker: AFM mRNA
Type: Predictive Biomarker (PRD)
Genes: AFM; ALB2; ALBA
Study 12496528 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 10910855 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1381018 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 1381018 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1381018 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6347498 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24144212 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study 8636753 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31504908 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 29701621 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 8847680 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 31802692 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31802692 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31802692 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 31802692 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 26324406 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 26324406 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19791830 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19791830 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 9143084 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3539306 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 22538270 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 10373752 — Biomarker: OPRM1
Type: Safety Biomarker (SAF)
Genes: MOR1; MOP
Study 27176122 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 10482997 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 10482997 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 10482997 — Biomarker: BCL6 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 2017535 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 28103948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18308157 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9526578 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 27398992 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 3886209 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 29499522 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26971332 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 28165634 — Biomarker: CACNA1G mRNA
Type: Predictive Biomarker (PRD)
Genes: CACNA1G; KIAA1123
Study 28165634 — Biomarker: CACNA1H mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CACNA1H
Study 28165634 — Biomarker: CACNA1I mRNA
Type: Predictive Biomarker (PRD)
Genes: CACNA1I; KIAA1120
Study 28165634 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 21459891 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 10733168 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 6713266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12415061 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7497558 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2023098 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2023098 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19640331 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17244765 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 21362327 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14693169 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 14693169 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 6425893 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 6425893 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 29843492 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 20826963 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16873779 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 10954063 — Biomarker: HBEGF mRNA
Type: Predictive Biomarker (PRD)
Genes: HBEGF; DTR; DTS; HEGFL
Study 8777332 — Biomarker: AKR1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKR1B1; ALDR1; ALR2
Study 30485224 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11052580 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 6695835 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 20528232 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 18662969 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 31152533 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31152533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23879671 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 23879671 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11704378 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11704378 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 2564505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30716942 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 28747487 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 21365345 — Biomarker: SFRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SFRP1; FRP; FRP1; SARP2
Study 21365345 — Biomarker: LEF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LEF1
Study 21365345 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 7519694 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21347968 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8923359 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3535473 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 27207552 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 7229121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)