AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 30248365 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 21293156 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10479220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7741542 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11850494 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 23911209 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 23911209 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19934619 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 18662417 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 15673874 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 30178484 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 20488759 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 12585188 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12585188 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 26341920 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 26341920 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 23731573 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 23731573 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9697781 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 26603917 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20857058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15459835 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15459835 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20628129 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 17587390 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17587390 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17587390 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11895158 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9861542 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 24232127 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20302678 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 1705432 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 8532025 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 1676368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30154493 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26411813 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17574929 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 9674467 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 9674467 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31412290 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31412290 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 30111683 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9458419 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 2466056 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23631785 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12894960 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8864322 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 8864322 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1728909 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22627104 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 20825986 — Biomarker: COL3A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL3A1
Study 11061616 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11061616 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11061616 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8320947 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24907722 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17587398 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 12698086 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 22964967 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 26054147 — Biomarker: MIA mRNA
Type: Predictive Biomarker (PRD)
Genes: MIA
Study 26054147 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 26054147 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24122908 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 15135261 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9610754 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22185725 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 17050637 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 17050637 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 17050637 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 17050637 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17050637 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 17050637 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 17050637 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 12808614 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7669957 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2185293 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 28548626 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 8636558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1637970 — Biomarker: CARTPT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CARTPT; CART
Study 28176893 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25523837 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19841299 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17078183 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14745710 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2487463 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 26618460 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26253887 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 26253887 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15692762 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 7556989 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7556989 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22288567 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 22288567 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 10594487 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 10594487 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 10594487 — Biomarker: CYP2E1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2E1; CYP2E
Study 10594487 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 10594487 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 10594487 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 29267900 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 29267900 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29267900 — Biomarker: Derived neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 29267900 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 26874645 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 22740283 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19554028 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19554028 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17506866 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11927516 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 11927516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2683546 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 2683546 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 14719288 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 11110056 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8986909 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8986909 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7708425 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26927664 — Biomarker: CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR1; C3BR
Study 16625235 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8677878 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 1659913 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 31036542 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31036542 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9772873 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2510657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25877802 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 24157649 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20390343 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 16110017 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 12355185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2341751 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11543695 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18326616 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15528283 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12854177 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29478970 — Biomarker: GHR mRNA
Type: Predictive Biomarker (PRD)
Genes: GHR
Study 29478970 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 10569660 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6482180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17707851 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11893228 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 7610938 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19384185 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 19939467 — Biomarker: GJB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GJB2
Study 17414902 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 31784280 — Biomarker: MFAP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFAP4
Study 29938621 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29938621 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27809886 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 25157115 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 8123862 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 21297494 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21297494 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15705206 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 12074350 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 11106916 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11106916 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 24559095 — Biomarker: YAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: YAP1; YAP65
Study 24559095 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20920186 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12211218 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 21862012 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 21862012 — Biomarker: ABCG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG1; ABC8; WHT1
Study 9399388 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2975595 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15579575 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25336703 — Biomarker: SRD5A2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SRD5A2
Study 25336703 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 12610024 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 2385209 — Biomarker: Argininosuccinate synthase
Type: Safety Biomarker (SAF)
Genes: ASS1; ASS
Study 6994760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29953014 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23013731 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 23013731 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 20047770 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20047770 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16936007 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 25218876 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25218876 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25218876 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30376366 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 27125363 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1926024 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11122797 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29056520 — Biomarker: VCAM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VCAM1
Study 29056520 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 24647737 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 24647737 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 16244024 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16244024 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16244024 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 12107602 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1903079 — Biomarker: DEK mRNA
Type: Predictive Biomarker (PRD)
Genes: DEK
Study 21785889 — Biomarker: CGAS mRNA
Type: Predictive Biomarker (PRD)
Genes: CGAS; C6orf150; MB21D1
Study 17440643 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17410124 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23723343 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17255304 — Biomarker: RAF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAF1; RAF
Study 17255304 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15124757 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 7898227 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31389909 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31389909 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31389909 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28255102 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 23414490 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23677653 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8883120 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24638013 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 24638013 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 7912725 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 21757458 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20071896 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16492702 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 16492702 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16492702 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16492702 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16492702 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 3510822 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30032977 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17931408 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10839761 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10839761 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29747957 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22418581 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15590212 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 15590212 — Biomarker: PLG mRNA
Type: Predictive Biomarker (PRD)
Genes: PLG
Study 15590212 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 15590212 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 29020251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17518957 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 27618821 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23890047 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19384192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2024569 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30715452 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25308787 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 21694537 — Biomarker: Fecal coefficient of fat absorption
Type: Surrogate Endpoint (SUR)
Study 8306366 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8306366 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12707981 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1451716 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8590895 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2