AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 11494442 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23839107 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21172891 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 2495813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27005817 — Biomarker: Insulin receptor substrate 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IRS1
Study 12439737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8557961 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8557961 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19300110 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19300110 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2439821 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24394187 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18222355 — Biomarker: KIF6 mRNA
Type: Predictive Biomarker (PRD)
Genes: KIF6; C6orf102
Study 18222355 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18222355 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11587165 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11587165 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9396419 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22262230 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16138795 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 11856154 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11856154 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 25037695 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 25037695 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21605716 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24887336 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15151839 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15151839 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11831545 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 23169801 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19709689 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19709689 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7700062 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 4921284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27899357 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 8574175 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 31882586 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 16953261 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11465642 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11465642 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27287832 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27287832 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24331381 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24331381 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 15017671 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 11200367 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28256104 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22511592 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 19935373 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 16796694 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 15273706 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 29778750 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 18955835 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18955835 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 16551862 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8706298 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28063503 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 23810688 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23810688 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19291931 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8198981 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28494895 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28494895 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30663788 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 30663788 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 30663788 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30663788 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 28373523 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 31207908 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17095943 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 22234084 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 8835618 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30038044 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18469239 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26284393 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11265777 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11265777 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 24954607 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 15911729 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15911729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10475418 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 20647390 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31820546 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 12955284 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 2653119 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 2653119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 902556 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20964739 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 19017883 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17380844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1902298 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29727016 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 29727016 — Biomarker: TFAM mRNA
Type: Predictive Biomarker (PRD)
Genes: TFAM; TCF6; TCF6L2
Study 29727016 — Biomarker: DNM1L mRNA
Type: Predictive Biomarker (PRD)
Genes: DNM1L; DLP1; DRP1
Study 29727016 — Biomarker: SOD2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SOD2
Study 29727016 — Biomarker: HSPA1B mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA1B; HSP72
Study 26018112 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 18437288 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9176650 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29090473 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 18387054 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 14673431 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 10545428 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 26946057 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 15789316 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22926161 — Biomarker: MTRR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTRR
Study 22926161 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 15615740 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 9828903 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9828903 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9828903 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 9828903 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 9828903 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 30761459 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 29530884 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 29530884 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29530884 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22337760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22337760 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8596484 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10051804 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31529104 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 18278078 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11828038 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 28408798 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16600583 — Biomarker: EDA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDA; ED1; EDA2
Study 10766183 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 10766183 — Biomarker: CD83 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD83
Study 10766183 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10766183 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 1864787 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22805286 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15345867 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11393673 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31219052 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 23359066 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 23359066 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16198451 — Biomarker: FCGR2A
Type: Predictive Biomarker (PRD)
Genes: CD32; CD32A; IGFR2; CDw32; Fc-gamma-RIIa; FcgammaRIIa
Study 26621483 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 24929235 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 20137789 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 11949767 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 11949767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10505032 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16923922 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16923922 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28744796 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27053384 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22085840 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20079899 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28770449 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 13678775 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10916115 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10023788 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 2224121 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 31277052 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21332722 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 21332722 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 17519315 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24958282 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 24958282 — Biomarker: CYP1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1B1
Study 24958282 — Biomarker: MDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM2
Study 24958282 — Biomarker: MDM4 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM4; MDMX
Study 24958282 — Biomarker: TP53BP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TP53BP1
Study 24958282 — Biomarker: ADH1C mRNA
Type: Predictive Biomarker (PRD)
Genes: ADH1C; ADH3
Study 30216917 — Biomarker: CACNA1C mRNA
Type: Predictive Biomarker (PRD)
Genes: CACNA1C; CACH2; CACN2; CACNL1A1; CCHL1A1
Study 26935057 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26935057 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 18333864 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 10412882 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31641967 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 31538180 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31538180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21976257 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29961816 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 20420761 — Biomarker: SLC2A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A2; GLUT2
Study 16942867 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16259175 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31365109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25774975 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25774975 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 19734256 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17143194 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 17143194 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9743401 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30897995 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18029171 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1348403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3994353 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 27435894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14969833 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22623396 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31521337 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21056606 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 21056606 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 26206095 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23642949 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9055905 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 2409278 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 2409278 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23574148 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23574148 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11917051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11917051 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11917051 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11917051 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 25960284 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 25960284 — Biomarker: S100A8 mRNA
Type: Predictive Biomarker (PRD)
Genes: S100A8; CAGA; CFAG; MRP8
Study 25960284 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25960284 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 9337183 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 20979460 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 31780332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23835715 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 19382089 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 31692553 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31692553 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 25117183 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 25117183 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 25117183 — Biomarker: SLC22A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A2; OCT2
Study 25117183 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 25117183 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17479946 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 820357 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30591415 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23475405 — Biomarker: BAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAK1; BAK; BCL2L7; CDN1
Study 17725739 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9514183 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9514183 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9050476 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 30137242 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 25494323 — Biomarker: LSS mRNA
Type: Predictive Biomarker (PRD)
Genes: LSS; OSC
Study 19469115 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10472854 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8752759 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12447551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1968731 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1968731 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22221684 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 16426267 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 16426267 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 31699568 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31699568 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27459721 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 25497995 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9625847 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 9625847 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 2686259 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19317378 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 2544345 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29179134 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29179134 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 25894531 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 25894531 — Biomarker: SCNN1A mRNA
Type: Predictive Biomarker (PRD)
Genes: SCNN1A; SCNN1
Study 17824291 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9645829 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9645829 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)