AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 18316115 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18316115 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18316115 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14698516 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 1721980 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31126570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22479361 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17515696 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9182470 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16369463 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 20406214 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 21763211 — Biomarker: CARTPT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CARTPT; CART
Study 21763211 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 16920590 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 9208358 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7778531 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28100544 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 21056284 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9032097 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 25135124 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25135124 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25135124 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 19933916 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18812366 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 1932484 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 30430667 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24808486 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 791330 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31395306 — Biomarker: PAG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAG1; CBP; PAG
Study 28151543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14738208 — Biomarker: APRT mRNA
Type: Predictive Biomarker (PRD)
Genes: APRT
Study 14738208 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 1384898 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29389579 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23970645 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12451982 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23028103 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 11820714 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 31665455 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 26806566 — Biomarker: High-frequency oscillations
Type: Pharmacodynamic Biomarker (PDY)
Study 16860028 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12701987 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 29917140 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 29917140 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22534335 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 30634036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20673325 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11092514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31025894 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22950816 — Biomarker: AZIN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AZIN2; ADC; KIAA1945; ODCP
Study 26857999 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26857999 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22552602 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 20377413 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 20377413 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30019318 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 30019318 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 16278262 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16278262 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9605804 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8581394 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8581394 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8581394 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 27644475 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10528035 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 6128875 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27951475 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20020207 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 25782323 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19318471 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15698940 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23514054 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23514054 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 23514054 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 17457340 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12940842 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10679756 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 8148487 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 8148487 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 2568211 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2568211 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 27436368 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 19536890 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 10748773 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7250173 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31020400 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 28351163 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28351163 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 28351163 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 26521223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1310465 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 1310465 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 23669880 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 23669880 — Biomarker: Insulin receptor substrate 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IRS1
Study 20063429 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 12742478 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10803800 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 30463831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27248440 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27248440 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20002624 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20002624 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20002624 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 18698545 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18698545 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18698545 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 18698545 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2522729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 5072236 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24373610 — Biomarker: PCSK7 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK7; LPC; PC7; PC8; SPC7
Study 18686631 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 18686631 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 16118546 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 16118546 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16118546 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14519753 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8965890 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 26329313 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 26329313 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11888869 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 25201152 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 22855633 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22855633 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 22855633 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 22855633 — Biomarker: HSPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPD1; HSP60
Study 22855633 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 21037443 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 18679829 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 18679829 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 19914598 — Biomarker: ALDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH2; ALDM
Study 18655556 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18655556 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18655556 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31448513 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 11497197 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8296738 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30572482 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21733334 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 21733334 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21733334 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 18772858 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9730298 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 23331240 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 9296422 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25052847 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 25052847 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 19535710 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9236673 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9236673 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 9236673 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9236673 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 9236673 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 9236673 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 21382512 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 18996868 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28045585 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 12537922 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6169578 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29863966 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 15019536 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 9222184 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 7702801 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25903799 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 1655315 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 26814235 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15837826 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12578875 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 12578875 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11347858 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3909840 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29438199 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18246429 — Biomarker: FGA mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGA
Study 31718583 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31718583 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 24690383 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31388720 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 22887834 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15335019 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 10930895 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9780100 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 18245904 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 18245904 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 12765983 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 8636587 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31028503 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19497624 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15588135 — Biomarker: DBH mRNA
Type: Predictive Biomarker (PRD)
Genes: DBH
Study 9228516 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28860166 — Biomarker: Angiopoietin-related protein 4
Type: Predictive Biomarker (PRD)
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 28860166 — Biomarker: ATF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATF3
Study 25769195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3707799 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30001944 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28557652 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 23893190 — Biomarker: Argininosuccinate synthase
Type: Safety Biomarker (SAF)
Genes: ASS1; ASS
Study 11151744 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 10606280 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 6337742 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6337742 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 19445819 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 15338257 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 31978882 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30446594 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 17551931 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10821722 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10821722 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10754344 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10754344 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21963017 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21963017 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18590111 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18590111 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 7773216 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26700065 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8556568 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 25587804 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11216965 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31233169 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11253266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25399731 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25399731 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18606612 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 24655485 — Biomarker: Insulin receptor substrate 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IRS1
Study 8536677 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 2194029 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18930646 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 14751650 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14751650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8453190 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21169142 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10364782 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 22796064 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21476029 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 30292589 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26848931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22943927 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11477926 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18334528 — Biomarker: PNPLA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PNPLA3; ADPN; C22orf20
Study 18334528 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18334528 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12571210 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 1680600 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 25926410 — Biomarker: LIPC mRNA
Type: Predictive Biomarker (PRD)
Genes: LIPC; HTGL
Study 15648502 — Biomarker: CFI mRNA
Type: Predictive Biomarker (PRD)
Genes: CFI; IF