AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 12791814 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11069197 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12402733 — Biomarker: SH2D1A mRNA
Type: Predictive Biomarker (PRD)
Genes: SH2D1A; DSHP; SAP
Study 24158248 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24158248 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 20395860 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 11699613 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 9591497 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 25381393 — Biomarker: Dihydrothymine dehydrogenase
Type: Safety Biomarker (SAF)
Genes: DPYD
Study 20115947 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20115947 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16011291 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11836281 — Biomarker: ELK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELK3; NET; SAP2
Study 11836281 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1974502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15450574 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15450574 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 15450574 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15450574 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8109545 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8109545 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30839405 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30839405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26817181 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31065701 — Biomarker: NEB mRNA
Type: Predictive Biomarker (PRD)
Genes: NEB
Study 21669426 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21669426 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12658027 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12658027 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28551590 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17687273 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 17687273 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 17687273 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 17687273 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 28734907 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 28734907 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 25204295 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 21072892 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 7442081 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23713604 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23587162 — Biomarker: IGFBP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP6; IBP6
Study 23587162 — Biomarker: TSPOAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPOAP1; BZRAP1; KIAA0612; RBP1; RIMBP1
Study 23587162 — Biomarker: PRB4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRB4
Study 23587162 — Biomarker: CEBPA mRNA
Type: Predictive Biomarker (PRD)
Genes: CEBPA; CEBP
Study 23587162 — Biomarker: G0S2 mRNA
Type: Predictive Biomarker (PRD)
Genes: G0S2
Study 23587162 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 23587162 — Biomarker: GPRC5A mRNA
Type: Predictive Biomarker (PRD)
Genes: GPRC5A; GPCR5A; RAI3; RAIG1
Study 23587162 — Biomarker: CYP26B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP26B1; CYP26A2; P450RAI2
Study 23587162 — Biomarker: PDGFC mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFC; SCDGF; UNQ174/PRO200
Study 19820031 — Biomarker: GHR mRNA
Type: Predictive Biomarker (PRD)
Genes: GHR
Study 19820031 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17078309 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 15020363 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 15020363 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10762505 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 20919542 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15811141 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19501215 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 19501215 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 23051684 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 2711919 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 24744384 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 26035319 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26035319 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23930028 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23930028 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8829017 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31122994 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22473250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22473250 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30609439 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26310513 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 26254056 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21422117 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18512789 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16598442 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 28351093 — Biomarker: ANGPTL8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANGPTL8; C19orf80; RIFL; UNQ599/PRO1185
Study 23791215 — Biomarker: BNC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BNC1; BNC
Study 17076224 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17076224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11770190 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2941206 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9488190 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25902885 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19700099 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 16720102 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 15261312 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24861411 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 11008905 — Biomarker: CDKN2A mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2A; CDKN2; MTS1
Study 2693915 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2693915 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 2693915 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2693915 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2693915 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 28078090 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26466483 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 22117606 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 17717203 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 9704777 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9704777 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 1726988 — Biomarker: TBX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TBX2
Study 1726988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28350787 — Biomarker: TOX mRNA
Type: Predictive Biomarker (PRD)
Genes: TOX; KIAA0808
Study 28350787 — Biomarker: REL mRNA
Type: Predictive Biomarker (PRD)
Genes: REL
Study 25247433 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16325937 — Biomarker: VPS39 mRNA
Type: Predictive Biomarker (PRD)
Genes: VPS39; KIAA0770; TLP; VAM6
Study 11244389 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1466329 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1466329 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1466329 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31690051 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 2868744 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6204149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29924507 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27371719 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27371719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25453520 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 20619139 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 15585567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10468758 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19842242 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 16785477 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14555255 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10983646 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8227900 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 8227900 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 15001596 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11331169 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 3107602 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 3107602 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25903109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23660180 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22489903 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 22489903 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 22489903 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20351325 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 17506785 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 15474697 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 7920872 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 2899062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24044216 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17951035 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 17951035 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12860336 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 2127537 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 19808342 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17996561 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 17996561 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3325220 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31366262 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 20724949 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 20724949 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20724949 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11487753 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 21939502 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21939502 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21939502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19108791 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19108791 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31811383 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14698649 — Biomarker: MAP3K8 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP3K8; COT; ESTF
Study 2059298 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24140166 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18561728 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15564950 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9486510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8397516 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 8397516 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 29900538 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22231540 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22231540 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22231540 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9323645 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 22743177 — Biomarker: C-C motif chemokine 4
Type: Monitoring Biomarker (MOI)
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 22743177 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25447444 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25447444 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 10660149 — Biomarker: CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR1; C3BR
Study 1325831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29356827 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 22382148 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 22382148 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19462314 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11226654 — Biomarker: Dermal blood flow
Type: Pharmacodynamic Biomarker (PDY)
Study 23430672 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23430672 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 23430672 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 23430672 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25528311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18357530 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26761970 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8864420 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 6679507 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15492491 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 20605876 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 20605876 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11966747 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9863502 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24417563 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 24417563 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24417563 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18777489 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16454155 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 27405968 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 27405968 — Biomarker: TFAM mRNA
Type: Predictive Biomarker (PRD)
Genes: TFAM; TCF6; TCF6L2
Study 27405968 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 27405968 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 18203070 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15557391 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15557391 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31394172 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25587059 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 8418273 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 26940692 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 12860493 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10527826 — Biomarker: Urokinase plasminogen activator surface receptor
Type: Monitoring Biomarker (MOI)
Genes: PLAUR; MO3; UPAR
Study 24960402 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 2963522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11743267 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11743267 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28657396 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25386830 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16453248 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 9413749 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 25910632 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 24192332 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21932025 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 16646033 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24530788 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 22550117 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12105117 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11816697 — Biomarker: IL1RN mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RN; IL1F3; IL1RA
Study 11816697 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 17012443 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11078487 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 1330942 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24841020 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23545284 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 16573311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12783039 — Biomarker: MYF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYF5; BHLHC2
Study 15915396 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7899535 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28551167 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 21656149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31254047 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 11861668 — Biomarker: PLTP mRNA
Type: Predictive Biomarker (PRD)
Genes: PLTP
Study 11861668 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 10417035 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10417035 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2281392 — Biomarker: SIGLEC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIGLEC1; SN
Study 31676252 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN