AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 28207537 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 15025216 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 11831591 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31599225 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12479764 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12479764 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28453240 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23511357 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 8373973 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27011304 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 22873565 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 22873565 — Biomarker: AIF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AIF1; G1; IBA1
Study 22873565 — Biomarker: HCG22 mRNA
Type: Predictive Biomarker (PRD)
Genes: HCG22; G2; PBMUCL2
Study 1690202 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 31272903 — Biomarker: MDC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDC1; KIAA0170; NFBD1
Study 23742912 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 6805499 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 6805499 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6805499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24114400 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18265482 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 16885405 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8213511 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18403223 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 24584926 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10866886 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10866886 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8212201 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8212201 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3544690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3544690 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 29398422 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12450903 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30806520 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 17100860 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1282588 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 1282588 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1282588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29762731 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 18072822 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10721156 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10721156 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2407885 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30726946 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 30726946 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 30726946 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 30726946 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 25000151 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23251355 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 31447409 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27299475 — Biomarker: CARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARS1; CARS
Study 26992609 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26992609 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 26992609 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 21325465 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21325465 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1968319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29908043 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 29908043 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16134998 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10023789 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7775644 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 2157231 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28321022 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 8860111 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24101043 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10806834 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 29231608 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 6994772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24498875 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24498875 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 22186099 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20560108 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20560108 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10361530 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11782871 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9840235 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 28705172 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28705172 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18826659 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8663871 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6409208 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 28679772 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9383806 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8031548 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2902274 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 30755265 — Biomarker: CACNA1C mRNA
Type: Predictive Biomarker (PRD)
Genes: CACNA1C; CACH2; CACN2; CACNL1A1; CCHL1A1
Study 28199903 — Biomarker: Complement factor D
Type: Safety Biomarker (SAF)
Genes: CFD; DF; PFD
Study 24292212 — Biomarker: TMPRSS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMPRSS2; PRSS10
Study 24892462 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22561774 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12390318 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 12390318 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12390318 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7539966 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2185673 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23868890 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 27128712 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 9363971 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9363971 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9363971 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18630536 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 12374459 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 7854155 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 29273130 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 29273130 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26562368 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17484865 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22914905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28424063 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15871195 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15871195 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 25165165 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19465798 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19465798 — Biomarker: AIP mRNA
Type: Predictive Biomarker (PRD)
Genes: AIP; XAP2
Study 15350001 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 7977479 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2658526 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 25748580 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23582482 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11854938 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27402817 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22147471 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 22147471 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20688622 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11045391 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31120574 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26538428 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 26538428 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 26538428 — Biomarker: CYP4F2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP4F2
Study 22685047 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15937634 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 15937634 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8969780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1370924 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16420199 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3302924 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30001572 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27502847 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20038231 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 20038231 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 11230635 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 27245553 — Biomarker: SLC22A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A2; OCT2
Study 27245553 — Biomarker: SLC47A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC47A1; MATE1
Study 453783 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31658289 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 25240532 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17441321 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 17441321 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 11504982 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9988364 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 9988364 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 30982271 — Biomarker: FAM131A mRNA
Type: Predictive Biomarker (PRD)
Genes: FAM131A; C3orf40; UNQ715/PRO1378
Study 30982271 — Biomarker: CAPN15 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPN15; SOLH
Study 30982271 — Biomarker: NFIC mRNA
Type: Predictive Biomarker (PRD)
Genes: NFIC; NFI
Study 30982271 — Biomarker: SHISA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SHISA5; SCOTIN; PSEC0133
Study 30982271 — Biomarker: FGF13 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF13; FHF2
Study 30982271 — Biomarker: Tetranectin
Type: Predictive Biomarker (PRD)
Genes: CLEC3B; TNA
Study 30982271 — Biomarker: LILRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LILRB2; ILT4; LIR2; MIR10
Study 16536664 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 11327445 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30742244 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30742244 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12887823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7555614 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7555614 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 22849962 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15988786 — Biomarker: SPARC mRNA
Type: Predictive Biomarker (PRD)
Genes: SPARC; ON
Study 11211570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30879358 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26850040 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26850040 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 26850040 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 24194532 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 24194532 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20576665 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11943521 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11943521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10084367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2147859 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 458893 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 19359647 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12577435 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 27810028 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 12390820 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9661591 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 1972139 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23841872 — Biomarker: BCL2A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCL2A1; BCL2L5; BFL1; GRS; HBPA1
Study 15448429 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31463484 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 19756419 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19756419 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2423799 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17914351 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22866290 — Biomarker: FGG mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGG; PRO2061
Study 17406813 — Biomarker: SLC5A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A1; NAGT; SGLT1
Study 28938473 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 22648467 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 1351673 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30469433 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30469433 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 19019358 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 19019358 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 19019358 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19019358 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19019358 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12187499 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12187499 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 6122483 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6122483 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 6122483 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25601538 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23900311 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 1874212 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31677181 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 26209863 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 15123224 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 10510951 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31449168 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31449168 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 31449168 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 25121719 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20139233 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7587005 — Biomarker: TPI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPI1; TPI
Study 26242122 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 26242122 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26242122 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 22966096 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 16878257 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24973361 — Biomarker: ASXL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASXL2; ASXH2; KIAA1685
Study 24973361 — Biomarker: ASXL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASXL1; KIAA0978
Study 7767 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11579707 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26166166 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 23214253 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23214253 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23214253 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16710252 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14567499 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1