AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 25196993 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21273183 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 21273183 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 16896884 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11756857 — Biomarker: GCA mRNA
Type: Predictive Biomarker (PRD)
Genes: GCA; GCL
Study 9008458 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29860040 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 24214881 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 21967019 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21033613 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 8913958 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 30075678 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 11600822 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8045951 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 17082468 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 9762656 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9762656 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 1695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10717600 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 7482430 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 7023672 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 7023672 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30815684 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 30815684 — Biomarker: MME mRNA
Type: Predictive Biomarker (PRD)
Genes: MME; EPN
Study 30815684 — Biomarker: Protein AMBP
Type: Safety Biomarker (SAF)
Genes: AMBP; HCP; ITIL
Study 30815684 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 24795252 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22176941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16988993 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16039210 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16039210 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 12015434 — Biomarker: PDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PDK4; PDHK4
Study 12015434 — Biomarker: UCP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP3; SLC25A9
Study 12015434 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 31884854 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31884854 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12083533 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 9725552 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 2528256 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27436788 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 22016505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27798024 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 24517156 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9314448 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 31273513 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 31273513 — Biomarker: ZAP70 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZAP70; SRK
Study 31273513 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 28271382 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19033020 — Biomarker: GPX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPX1
Study 10875609 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 10875609 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10875609 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 10875609 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12139118 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 1089522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27721013 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 27363424 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 31353666 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26666876 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26666876 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 26666876 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26666876 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18785581 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 25223728 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 11873074 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 31033162 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 30028657 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12468561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21816845 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7881704 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7881704 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18586644 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3094360 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29750261 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 24906029 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 22502793 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15631865 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15631865 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9878016 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2189075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26206423 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 26206423 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 8126502 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 24019134 — Biomarker: HGD mRNA
Type: Predictive Biomarker (PRD)
Genes: HGD; HGO
Study 16951474 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31399793 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21696635 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9275372 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30552505 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31089253 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31089253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30359215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30359215 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27865620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27865620 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11235707 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 28904068 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14967868 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 10977787 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 10977787 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22393101 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22393101 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 16487032 — Biomarker: TNFSF10 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF10; APO2L; TRAIL
Study 24559003 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18356793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17210383 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16338562 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 2223348 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 25727104 — Biomarker: LSR mRNA
Type: Predictive Biomarker (PRD)
Genes: LSR; ILDR3; LISCH
Study 15636216 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 11078488 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 1857729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6409917 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 25493953 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25493953 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23070057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19635719 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 19635719 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 19635719 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12885981 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9491504 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 9098468 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 29759063 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 25064723 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25064723 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18555575 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 323298 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24019047 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 19663521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30627512 — Biomarker: AOX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AOX1; AO
Study 20649060 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 18379501 — Biomarker: CPD mRNA
Type: Predictive Biomarker (PRD)
Genes: CPD
Study 16076940 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18946011 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 16981000 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 15134308 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24798786 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 15756217 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15756217 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10693099 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 31670388 — Biomarker: BLK mRNA
Type: Predictive Biomarker (PRD)
Genes: BLK
Study 25814467 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 22087846 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 18635446 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18635446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12845731 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 26197451 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22343536 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28376899 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25406260 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 25406260 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 23813322 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21708042 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 19699875 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 1284152 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 1284152 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 29265934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12598351 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9890307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29902939 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25475143 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 1613273 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 87965 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 8467322 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30344655 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 30344655 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30344655 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30344655 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11056593 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 11206674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6116607 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23324658 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7512805 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20827548 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19671398 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 17453751 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30720034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28865866 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 28865866 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21576282 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 21576282 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21576282 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21576282 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12063773 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 12063773 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22119513 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 15031571 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9735578 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 8296409 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8296409 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 2737789 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 820882 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16868063 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12601103 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24769189 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18194384 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 15993933 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30225878 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27710240 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18626299 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14679383 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8439095 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 3531452 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 27128665 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 27128665 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29683391 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26979136 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 28107273 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 25136625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15660859 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 9058176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18088241 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 16527014 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12866606 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29691246 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 28716522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26179482 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 26179482 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21441078 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18202030 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22207070 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 19955891 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17429784 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26589253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22717420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20151774 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18082876 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 12399191 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study 20379742 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 10353863 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 10353863 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2057620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20519076 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 9875065 — Biomarker: RTN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RTN1; NSP
Study 21261621 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 21261621 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 11106141 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 9377067 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 30409131 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19000553 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 19000553 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 16308008 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 12617335 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10554126 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28767146 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28767146 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3146403 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK