AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 16357163 — Biomarker: GDNF mRNA
Type: Predictive Biomarker (PRD)
Genes: GDNF
Study 16357163 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 9044338 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1526096 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22435937 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22435937 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16259492 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14742356 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 14742356 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 26625506 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18951296 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 10843169 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24337978 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22395187 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 18399898 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 18399898 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 12750099 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 12750099 — Biomarker: GLS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS2; GA
Study 12750099 — Biomarker: HRC mRNA
Type: Predictive Biomarker (PRD)
Genes: HRC; HCP
Study 10550454 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8905799 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 28303364 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28303364 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25209368 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 16492611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3578422 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 17932377 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17932377 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17932377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1306606 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30457230 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 14610474 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 14610474 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 14610474 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8718563 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25882973 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 24273968 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 16839836 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29253747 — Biomarker: MYD88 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYD88
Study 29253747 — Biomarker: TICAM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TICAM1; PRVTIRB; TRIF
Study 29253747 — Biomarker: IRAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRAK1; IRAK
Study 29253747 — Biomarker: Interferon regulatory factor 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: IRF3
Study 29253747 — Biomarker: IRF7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRF7
Study 29253747 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29253747 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 29253747 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31356432 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 27129183 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 15664003 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6788167 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24942311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1373372 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 26187555 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16700881 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 16700881 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16700881 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16700881 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10781127 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1465036 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 6146570 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11792604 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1449110 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 23379386 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 23924044 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2189027 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2189027 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31488314 — Biomarker: TRIM32 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM32; HT2A
Study 30886125 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 24282229 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19143751 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 19143751 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19143751 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17695377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9613308 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25790022 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 20805297 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11115442 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9099188 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25071343 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25071343 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12689976 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8724709 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 1860094 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30997967 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 27993381 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 25202068 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 25202068 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20879046 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 12089368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12089368 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2565105 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27515804 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 27515804 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 21806769 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8496313 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12846772 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10843158 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6391005 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1951242 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 19896213 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 19896213 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 11271785 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25592656 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 30204244 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 19416992 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15127325 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11256540 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11256540 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30804129 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 26143297 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 26143297 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 11421998 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3511650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3511650 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 23413535 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18443034 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 15983224 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 29056249 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29056249 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 29056249 — Biomarker: CMIP mRNA
Type: Predictive Biomarker (PRD)
Genes: CMIP; KIAA1694; TCMIP
Study 29056249 — Biomarker: CXCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR5; BLR1; MDR15
Study 15752944 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15752944 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2971131 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 2971131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27218270 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 27218270 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21707573 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 22464340 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17530097 — Biomarker: HSPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPD1; HSP60
Study 1343377 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16439720 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 21993599 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 802649 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19736473 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17009077 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 17009077 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17009077 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26782853 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 26782853 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17767636 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28676211 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 2301216 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19283449 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2191783 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 22996693 — Biomarker: CXCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR1; CMKAR1; IL8RA
Study 22996693 — Biomarker: CXCL1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 22996693 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 1751651 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30388595 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30388595 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30388595 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 30388595 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 30195882 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15793869 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15793869 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 15793869 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 4054195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21700935 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21700935 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17238390 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9003815 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3068400 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 27455835 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 23011562 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21510583 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28493293 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 28493293 — Biomarker: CCL22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 28493293 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC
Study 21863617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17187936 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8186281 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25747197 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25747197 — Biomarker: Angiopoietin-1
Type: Monitoring Biomarker (MOI)
Genes: ANGPT1; KIAA0003
Study 1184719 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 19430945 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19430945 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19430945 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19430945 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19430945 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19430945 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 22457015 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12366781 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 12366781 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 12366781 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 24851582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31264950 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23831913 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21183326 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9869017 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31408531 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 31408531 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 31408531 — Biomarker: BCL6 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 28334771 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 16582575 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 16582575 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11789206 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11789206 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 11511333 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 27525826 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 27525826 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 16378562 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29257986 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 30919909 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 27865639 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 27865639 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 27865639 — Biomarker: GNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNL3; E2IG3; NS
Study 27865639 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 12508046 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1517614 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 6712030 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29879048 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25027338 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25027338 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25027338 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25027338 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 25027338 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 25027338 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23636616 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 19002467 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2628537 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30205020 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28039545 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 25738212 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21872439 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11604622 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 11604622 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 29483080 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27363733 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27363733 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 24120618 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31287010 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 29871798 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 22033897 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 2184789 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2184789 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20540445 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20540445 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 10715786 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 7767523 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 31755959 — Biomarker: IFIH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFIH1; MDA5; RH116
Study 19710199 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1