AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 12047485 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7109499 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 25149596 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 17472472 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 11981081 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10512898 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23743741 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 15565596 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15565596 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12445025 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30496299 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 26399404 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19137863 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10760336 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7674882 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 24511648 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18347680 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3174724 — Biomarker: OTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 29904824 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23175340 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2679258 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 27790824 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31485864 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22449201 — Biomarker: CPOX mRNA
Type: Predictive Biomarker (PRD)
Genes: CPOX; CPO; CPX
Study 22449201 — Biomarker: MYRF mRNA
Type: Predictive Biomarker (PRD)
Genes: MYRF; C11orf9; KIAA0954; MRF
Study 22367664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2520637 — Biomarker: FGFR1
Type: Predictive Biomarker (PRD)
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 19381522 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 10912546 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 24252943 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 29940565 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 19654232 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 19581770 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17975845 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 25204361 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 23144466 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 23144466 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 29202566 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 25027139 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 19264840 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 11991558 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9203448 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28592888 — Biomarker: TLX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLX1; HOX11; TCL3
Study 28592888 — Biomarker: BARHL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BARHL1; FKSG31
Study 28592888 — Biomarker: BARX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BARX2
Study 28592888 — Biomarker: EMX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EMX2
Study 28592888 — Biomarker: LBX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LBX2; LP3727
Study 28592888 — Biomarker: MSX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MSX2; HOX8
Study 11087536 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 31004339 — Biomarker: ADAM11 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ADAM11; MDC
Study 8985623 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27380342 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 10616997 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7488409 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 7488409 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 31365099 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 28087235 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11730275 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 11730275 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11730275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9570827 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 21084429 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 16186995 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7353349 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23483886 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20175428 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20175428 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12808485 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12808485 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27332677 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 23630215 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 16934729 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 2522007 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21956102 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21956102 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 21956102 — Biomarker: CYP1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1B1
Study 7672138 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 30689707 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30689707 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 30689707 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 30689707 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 30338823 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 20368558 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16269401 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 27102200 — Biomarker: CYP19A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 27102200 — Biomarker: PPARG mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARG; NR1C3
Study 27102200 — Biomarker: PPARGC1A mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1
Study 27102200 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 18087553 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12473877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23952289 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23952289 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 16160626 — Biomarker: NE
Type: Predictive Biomarker (PRD)
Study 3303886 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 25867913 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25867913 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19576015 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19576015 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16784647 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18976766 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 18976766 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11223729 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 29353534 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25592133 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21486976 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10873733 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9069163 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27321165 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 27321165 — Biomarker: SLCO1B3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 24801467 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 22595386 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18035098 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30630371 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30630371 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 30630371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30630371 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 14998784 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 11464450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11464450 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28783858 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21128816 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 24420987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17661935 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 9196163 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15927063 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19474284 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16636870 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 16135178 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 28969327 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 26255515 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 15225901 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15225901 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 16054522 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 7554318 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 7554318 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 7554318 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 26791477 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26791477 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17255748 — Biomarker: TNFRSF10A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 9813512 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17533209 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17533209 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 56903 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 29088099 — Biomarker: CCL24 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL24; MPIF2; SCYA24
Study 16145319 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 16145319 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 10089978 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 7844665 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 22327087 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22327087 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18752692 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16248242 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study 11137328 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11137328 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29358194 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1283588 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1283588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1283588 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1283588 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 1283588 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1283588 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21555676 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16710287 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3292710 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12496063 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 2126420 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 11403352 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8139992 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3260641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15266074 — Biomarker: Hypoxanthine-guanine phosphoribosyltransferase
Type: Safety Biomarker (SAF)
Genes: HPRT1; HPRT
Study 8466006 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17599425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15848601 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15848601 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10527967 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 20150572 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11533541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8311374 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26474870 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 26474870 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17956570 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 15997871 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15997871 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9385113 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18201432 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15716985 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 19335986 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 1525604 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26800231 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 24189107 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study 17444589 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7753339 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 7753339 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 31337172 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 26141305 — Biomarker: POR mRNA
Type: Predictive Biomarker (PRD)
Genes: POR; CYPOR
Study 11416689 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31660848 — Biomarker: ELF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELF3; ERT; ESX; JEN
Study 26004162 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study 9216132 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7965851 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25672163 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21875410 — Biomarker: GDNF mRNA
Type: Predictive Biomarker (PRD)
Genes: GDNF
Study 21875410 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 21875410 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 12938827 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 12938827 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12938827 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8617896 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 9513798 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 31291977 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 18345020 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 18345020 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 12685616 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12685616 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9192926 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30103444 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19874728 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 3896594 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25273343 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25273343 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15767470 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 9139273 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9139273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1660514 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 27842383 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25145934 — Biomarker: miR-21
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR21
Study 21937805 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 21937805 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 17709451 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 31104167 — Biomarker: DHCR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: DHCR7; D7SR
Study 22990757 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22990757 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21724703 — Biomarker: MGP mRNA
Type: Predictive Biomarker (PRD)
Genes: MGP; MGLAP; GIG36
Study 23091707 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20570122 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 12122096 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31455407 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 31455407 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 19963158 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19963158 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19963158 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15472177 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15472177 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16344495 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 16344495 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 16344495 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14736007 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8651094 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6384250 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG