AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 7669532 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 26079649 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 16555056 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16555056 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16555056 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 24999798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14694498 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31238631 — Biomarker: CCL20 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL20; LARC; MIP3A; SCYA20
Study 31238631 — Biomarker: TNNT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNNT1; TNT
Study 17005278 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8287640 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30053162 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25110439 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 12374234 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23563442 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 23563442 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 23563442 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 1560429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2865150 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30698629 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 22450428 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22450428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26551637 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 20595645 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20595645 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20595645 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18006422 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 10870037 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 10870037 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 30394834 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30394834 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27531132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6344591 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 30097364 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26022945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23143842 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15918064 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 14633753 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 14633753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17890860 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 8068212 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30050655 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 30050655 — Biomarker: SOD2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SOD2
Study 30050655 — Biomarker: GPX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPX1
Study 24734285 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 20110249 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 18427279 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18427279 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 1854570 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26956618 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29258763 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18349060 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1540362 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20078609 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17686882 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31837988 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28453843 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 28453843 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28453843 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 28453843 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28453843 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 28453843 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 17460329 — Biomarker: TEF mRNA
Type: Predictive Biomarker (PRD)
Genes: TEF; KIAA1655
Study 31606815 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 30602311 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24081023 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24081023 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19122354 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12364431 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11333010 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11333010 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30648598 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30648598 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25332249 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17376268 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2149688 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 28553847 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22940818 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 19237568 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7524159 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21762357 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19092234 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10818025 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 26437712 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 17590156 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 17590156 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10412726 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10412726 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7032811 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6704545 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 23416308 — Biomarker: TLR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR7; UNQ248/PRO285
Study 21135022 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 15329205 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 15329205 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 15329205 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 15329205 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 25567150 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15340532 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11589607 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9598254 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7834990 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3165298 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 23485864 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 23485864 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 21428766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21428766 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23871267 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 12962750 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 23009891 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 23009891 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18006170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9345434 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 1675763 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7148732 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28457217 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22383996 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17463140 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 17463140 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17463140 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 17463140 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30955400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30517599 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21779873 — Biomarker: SLC30A8 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC30A8; ZNT8
Study 9805693 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7112396 — Biomarker: MERTK mRNA
Type: Predictive Biomarker (PRD)
Genes: MERTK; MER
Study 30522922 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 18003042 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16117818 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 16117818 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 12191566 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29870855 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 29870855 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24623067 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 19074534 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15124006 — Biomarker: TPH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH2; NTPH
Study 12235444 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 7859051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7859051 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 2698934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28034079 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28034079 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17290039 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 17290039 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 8896396 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8896396 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 8896396 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 31093657 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 25179916 — Biomarker: TNFSF13 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 17062764 — Biomarker: PDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PDK4; PDHK4
Study 17062764 — Biomarker: PDK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PDK2; PDHK2
Study 7925518 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7925518 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 2511299 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 30591410 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 25561281 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 25561281 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16508590 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31785994 — Biomarker: Osteopontin
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SPP1; BNSP; OPN; PSEC0156
Study 31785994 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 24312194 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20167684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10535703 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8561070 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 8561070 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 6125188 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19008724 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30834812 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 29423521 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29423521 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 29423521 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 26813548 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26813548 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21059972 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21059972 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18925883 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16687966 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3490176 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 3490176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24438094 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24438094 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24438094 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22722501 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30001547 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 20403483 — Biomarker: KIF6 mRNA
Type: Predictive Biomarker (PRD)
Genes: KIF6; C6orf102
Study 10380089 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 31997084 — Biomarker: SLCO1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 15257733 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 8608073 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25490675 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25490675 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17686832 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17686832 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 17686832 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31358032 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 28099485 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 24026560 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 24026560 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8799530 — Biomarker: MPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: MPZ
Study 1600971 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2858186 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 31466813 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 25171552 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 10962867 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 6725527 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10548188 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 10548188 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10548188 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8517061 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 3481814 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 3481814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31736269 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 31736269 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 31736269 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31736269 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 31736269 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29164797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25618791 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 25618791 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 21511212 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16935343 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 15293170 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 8004320 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21505349 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21505349 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9113009 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20929598 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 18356628 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18356628 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18356628 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 10337457 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9110055 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31348336 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19478258 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19478258 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 6138935 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 16369229 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29909057 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 26879693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)