AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 15696181 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 1332529 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15886286 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10636578 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 10636578 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26182172 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23636283 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19689798 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 19689798 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 19689798 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 19689798 — Biomarker: FADS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS1; FADSD5
Study 19689798 — Biomarker: UCP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP2; SLC25A8
Study 19689798 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 19689798 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 19689798 — Biomarker: NFAT5 mRNA
Type: Predictive Biomarker (PRD)
Genes: NFAT5; KIAA0827; TONEBP
Study 19689798 — Biomarker: CREB5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CREB5; CREBPA
Study 17239165 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 17239165 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 11521985 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30760195 — Biomarker: NOS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOS2; NOS2A
Study 21966218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21966218 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14561117 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 30245169 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 22781352 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 28592620 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28592620 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 21943112 — Biomarker: ADIPOR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOR2; PAQR2
Study 9093424 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 31468664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31468664 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 9383115 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9383115 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 9383115 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22236804 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21512577 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16776702 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 9324147 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28101658 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21600090 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 17068818 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12511312 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10371571 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10371571 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 10371571 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31814159 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 31814159 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 17523932 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 15050199 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 2455107 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1579579 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29498344 — Biomarker: EED mRNA
Type: Predictive Biomarker (PRD)
Genes: EED
Study 29498344 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 1413981 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31331587 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17413099 — Biomarker: Insulin receptor substrate 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IRS1
Study 10195235 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30614013 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 23275453 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19778663 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 11256875 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29092982 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29092982 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21331773 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11061604 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 31300951 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 31219248 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 25873097 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21114549 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21114549 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11036120 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8412414 — Biomarker: AMPH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMPH; AMPH1
Study 20205482 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 15889312 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8558208 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 1757027 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 30982776 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 27087080 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 27087080 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22422593 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 12378376 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12378376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31754239 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31754239 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31754239 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25496000 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 23407049 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 19820812 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30239290 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 29629400 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 10614716 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1930849 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1930849 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 9869503 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9869503 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 21296780 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21296780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7743570 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28376768 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16034276 — Biomarker: SNAP25 mRNA
Type: Predictive Biomarker (PRD)
Genes: SNAP25; SNAP
Study 8085776 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30511840 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26447153 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 23359034 — Biomarker: FBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBP1; FBP
Study 23359034 — Biomarker: CNR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNR1; CNR
Study 19411747 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24006673 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 25329159 — Biomarker: FADS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS2
Study 25329159 — Biomarker: ELOVL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELOVL5; ELOVL2; PRO0530
Study 24767423 — Biomarker: SNAP25 mRNA
Type: Predictive Biomarker (PRD)
Genes: SNAP25; SNAP
Study 26250486 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9329359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20673995 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10847232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31177999 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31177999 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25896121 — Biomarker: PICALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PICALM; CALM
Study 20103314 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15961531 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 12165184 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31689951 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 19567515 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15969668 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2283646 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19020533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19020533 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27493198 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15482599 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 12014386 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12643118 — Biomarker: CALD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CALD1; CAD; CDM
Study 29408562 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27033026 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27033026 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23225089 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 10857934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7931189 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 3290578 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 3290578 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 31734452 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16076733 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 12074764 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 20131073 — Biomarker: CPD mRNA
Type: Predictive Biomarker (PRD)
Genes: CPD
Study 31941539 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 16332650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12389003 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9665096 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28929816 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 19465485 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 10950441 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 10216806 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10216806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19661193 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15918296 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 12816681 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 11783172 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 29145308 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 18853093 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10099042 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2667525 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 2667525 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 10842262 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 10842262 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21955475 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 21955475 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 21955475 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11705307 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29432650 — Biomarker: PTN mRNA
Type: Predictive Biomarker (PRD)
Genes: PTN; HBNF1; NEGF1
Study 12515745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8880557 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22842994 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20542512 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20542512 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9286467 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9286467 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8416077 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 25412862 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 18560218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15836828 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15836828 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15836828 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15836828 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15836828 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15836828 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 10084094 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29367439 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27928077 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22781526 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20234330 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 31306043 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31306043 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31306043 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28448655 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28448655 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26210387 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 21859655 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21859655 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 9933852 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 30876831 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 26591005 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 16227145 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12105241 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21610364 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27824680 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2568202 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25065959 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 23062105 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 21996202 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21996202 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21996202 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10428734 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10428734 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11914748 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2137279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29698983 — Biomarker: miR-133a
Type: Safety Biomarker (SAF)
Study 24505281 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24505281 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 31468473 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 31468473 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31468473 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31290996 — Biomarker: LYN mRNA
Type: Predictive Biomarker (PRD)
Genes: LYN; JTK8
Study 19303940 — Biomarker: PLTP mRNA
Type: Predictive Biomarker (PRD)
Genes: PLTP
Study 19303940 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 19303940 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 15179345 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 16397311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21654266 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 16356696 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 8733686 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 8733686 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9137901 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9137901 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7982251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23264399 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 23264399 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24408120 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 24408120 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 17270510 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 11829199 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7531327 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 25697830 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15893402 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26730967 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 19848045 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11923038 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11923038 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11923038 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 11923038 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 9577931 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9577931 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 26527777 — Biomarker: SHH mRNA
Type: Predictive Biomarker (PRD)
Genes: SHH