AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 18603947 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 8703450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28965100 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 29668352 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 25054390 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20079572 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 12798894 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 8770965 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8770965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1628410 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31606364 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31606364 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30307304 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25228130 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 22410137 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 19111163 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 30851630 — Biomarker: SLC52A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC52A2; GPR172A; PAR1; RFT3
Study 30851630 — Biomarker: F2RL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F2RL3; PAR4
Study 15593389 — Biomarker: AQP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP4
Study 3877288 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 15892618 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 15892618 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 15892618 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 15892618 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27278926 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27278926 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27278926 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27278926 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27278926 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19084376 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19084376 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19084376 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22178004 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 22178004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15956124 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9426846 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 3886399 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19892663 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19892663 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 19892663 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19892663 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 19892663 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 10932333 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20688462 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 24641841 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 23394502 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 20423844 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 22552800 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 14513268 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2256863 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 25637340 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 24629635 — Biomarker: PSME1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSME1; IFI5111
Study 24629635 — Biomarker: ECM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ECM1
Study 24629635 — Biomarker: YES1 mRNA
Type: Predictive Biomarker (PRD)
Genes: YES1; YES
Study 24629635 — Biomarker: BGN mRNA
Type: Predictive Biomarker (PRD)
Genes: BGN; SLRR1A
Study 24629635 — Biomarker: CNDP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNDP1; CN1; CPGL2; UNQ1915/PRO4380
Study 24629635 — Biomarker: MRC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MRC2; CLEC13E; ENDO180; KIAA0709; UPARAP
Study 24629635 — Biomarker: ADAM9 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM9; KIAA0021; MCMP; MDC9; MLTNG
Study 24629635 — Biomarker: CDON mRNA
Type: Predictive Biomarker (PRD)
Genes: CDON; CDO
Study 24629635 — Biomarker: KLRK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRK1; D12S2489E; NKG2D
Study 15005721 — Biomarker: RAB3A mRNA
Type: Predictive Biomarker (PRD)
Genes: RAB3A
Study 11307656 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 30954360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19366489 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 7945622 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7945622 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 7945622 — Biomarker: Interleukin 1 alpha
Type: Safety Biomarker (SAF)
Genes: IL1A; IL1F1
Study 7945622 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7945622 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30922297 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30922297 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29362371 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 28077531 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22380717 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 22380717 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 22380717 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15920008 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9893189 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9893189 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21678095 — Biomarker: MAVS mRNA
Type: Predictive Biomarker (PRD)
Genes: MAVS; IPS1; KIAA1271; VISA
Study 17716550 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15800139 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 10385578 — Biomarker: LIPC mRNA
Type: Predictive Biomarker (PRD)
Genes: LIPC; HTGL
Study 8723144 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 6805588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31907776 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 31764099 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28294173 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28294173 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28294173 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22568828 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 15080865 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 9284696 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21302490 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17967831 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18603575 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 15860983 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15860983 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15860983 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 1880885 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30762760 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25326074 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11693763 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11693763 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27058904 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 12675669 — Biomarker: GSN mRNA
Type: Predictive Biomarker (PRD)
Genes: GSN
Study 9588444 — Biomarker: PTPRN mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRN; ICA3; ICA512
Study 2644342 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28619301 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28619301 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 21722499 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31242333 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 28667207 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 26137844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24065808 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 16784972 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16784972 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11245352 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 9399606 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22275399 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20737140 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2899510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23299761 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 23299761 — Biomarker: T-cell specific protein RANTES
Type: Safety Biomarker (SAF)
Genes: CCL5; D17S136E; SCYA5
Study 15311098 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15311098 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8151265 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8151265 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8151265 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8151265 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8151265 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 26319283 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 19321009 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11470718 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21471141 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 17051589 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 17051589 — Biomarker: NANOS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS3; NOS3
Study 17051589 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 1888787 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19356104 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 19356104 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 8624772 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8624772 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16181532 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16181532 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8758013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31806021 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 26211605 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8187316 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 8187316 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 8187316 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21293249 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19878577 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19878577 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14687095 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29562405 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29562405 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29562405 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 29562405 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 23425543 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 21274861 — Biomarker: ITPA mRNA
Type: Predictive Biomarker (PRD)
Genes: ITPA; C20orf37; My049; OK/SW-cl.9
Study 31912523 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 6813484 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28229508 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 8527353 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8527353 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2689045 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26314451 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 26314451 — Biomarker: Mitochondrial membrane potential
Type: Pharmacodynamic Biomarker (PDY)
Study 26314451 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 17139433 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2870944 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 25132122 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 2744799 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 25616927 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 23505929 — Biomarker: Urokinase plasminogen activator surface receptor
Type: Monitoring Biomarker (MOI)
Genes: PLAUR; MO3; UPAR
Study 14653030 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 14653030 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11096046 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8445223 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 16410734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16410734 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9332329 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3094063 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 20299628 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 1961958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6789294 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 24462012 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24462012 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17356966 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16332659 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16332659 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 16332659 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 16332659 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 16332659 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 16332659 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 28339738 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28339738 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29664836 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25343949 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 19037576 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 19037576 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17917504 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 17917504 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15389230 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7972616 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 15769986 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15769986 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10406153 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 24937643 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 24937643 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 10467325 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 29677190 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 8757525 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8757525 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 8757525 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8757525 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 8757525 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 29231452 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 22876438 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 22876438 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 22876438 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22876438 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22876438 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22876438 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 22876438 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 22876438 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10378706 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 10378706 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26471114 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 22243494 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 12444178 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 10349300 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 25147079 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)