AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23850055 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 1613201 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 29901704 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 404962 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16224053 — Biomarker: CX3CL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CX3CL1; FKN; NTT; SCYD1; A-152E5.2
Study 16224053 — Biomarker: CX3CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CX3CR1; CMKBRL1; GPR13
Study 16224053 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 21701406 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 18372036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11164440 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11164440 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 11164440 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11164440 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9206670 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 3707649 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 30081801 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30081801 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26899608 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21070920 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9581666 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18568960 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16423096 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11821634 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11821634 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29241199 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17318022 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 17318022 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15203784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24050416 — Biomarker: COPE mRNA
Type: Predictive Biomarker (PRD)
Genes: COPE
Study 19912735 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 19912735 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 17215115 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 29310326 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19632953 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9430359 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 26178282 — Biomarker: SRM mRNA
Type: Predictive Biomarker (PRD)
Genes: SRM; SPS1; SRML1
Study 21733322 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 21733322 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 21733322 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9166393 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9166393 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 20977639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15837256 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11886767 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11886767 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 11886767 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 10334534 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8547939 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2041284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30841568 — Biomarker: SLC25A20 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A20; CAC; CACT
Study 30841568 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 30841568 — Biomarker: LPCAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LPCAT1; AYTL2; PFAAP3
Study 30841568 — Biomarker: PLA2G4A mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G4A; CPLA2; PLA2G4
Study 30841568 — Biomarker: ALOX5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALOX5; LOG5
Study 30841568 — Biomarker: PTGER3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGER3
Study 30841568 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 30841568 — Biomarker: TCF7L2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCF7L2; TCF4
Study 30841568 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 10848851 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9116627 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 29743334 — Biomarker: PRKD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKD1; PKD; PKD1; PRKCM
Study 29743334 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 25241324 — Biomarker: Clusterin
Type: Safety Biomarker (SAF)
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 21474566 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 10363856 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 1782100 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 30626939 — Biomarker: DLK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DLK1; DLK
Study 23313567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19301686 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15514264 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27712015 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 27712015 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 27712015 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27712015 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 27712015 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24891327 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 20650046 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18614998 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18614998 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8772222 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 8772222 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 24098467 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24098467 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19158122 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 19158122 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19158122 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17338996 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17338996 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 17338996 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17338996 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10711861 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 10711861 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9248764 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 26429200 — Biomarker: miR-192
Type: Safety Biomarker (SAF)
Genes: MIR192
Study 26429200 — Biomarker: miR-146a
Type: Safety Biomarker (SAF)
Genes: MIR146A
Study 26429200 — Biomarker: miR-15a
Type: Safety Biomarker (SAF)
Genes: MIR15A
Study 26429200 — Biomarker: miR-21
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR21
Study 20404738 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18779612 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 11217593 — Biomarker: TPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH1; TPH; TPRH; TRPH
Study 3131470 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 21558582 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 19705041 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 15042531 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 31736069 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21901256 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21901256 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21901256 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21901256 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15988404 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15988404 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 15988404 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 7698300 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29888580 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12974590 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8677754 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8677754 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 1577028 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23537008 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23537008 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 23537008 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 14515937 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 25794890 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 23018784 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16816950 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 1715503 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 18356253 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 14656275 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 30720582 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 24401089 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18074937 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 10648270 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22727972 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 16995975 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 29798127 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 26245802 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28886907 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 19208729 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19208729 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2839019 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25740979 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20176450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16545724 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 16545724 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 1389714 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15071488 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2919758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1313120 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 1313120 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10920832 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 9012304 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25781214 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23234408 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19228175 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 8435972 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25079465 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31179920 — Biomarker: FGA mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGA
Study 28841230 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 15266173 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 7193603 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 23333777 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 23333777 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21392395 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29529387 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23866906 — Biomarker: SP9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP9
Study 23866906 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 20593240 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 8779402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29601997 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16187007 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10459816 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7541236 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31881421 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26524046 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2529294 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 31924637 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20413297 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20413297 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11958302 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 8790030 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18520806 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 15637747 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 12069179 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8776071 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 6286734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6286734 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2153765 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 22441634 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 20423436 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 15954959 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30299258 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27883295 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 27883295 — Biomarker: SLC5A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A6; SMVT
Study 27883295 — Biomarker: ABCB4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCB4; MDR3; PGY3
Study 27883295 — Biomarker: ABCC5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC5; MRP5
Study 25125580 — Biomarker: TRPM8 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPM8; LTRPC6; TRPP8
Study 15834703 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15834703 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9822137 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9822137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25505238 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 18807247 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 18807247 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 6996121 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 22040532 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17508621 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 16285996 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 16285996 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 17149760 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 15894479 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15894479 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 15894479 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 7999488 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2904310 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18358927 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18358927 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10916812 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23620937 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 9095079 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9095079 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3780818 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20693886 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20693886 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20693886 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20693886 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 20693886 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 20693886 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 18842789 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1