AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23370069 — Biomarker: PICALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PICALM; CALM
Study 18451314 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 9559790 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8582392 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 756039 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 756039 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30586701 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28457231 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24971677 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10326065 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1788750 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6267643 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23974250 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9151148 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 23590389 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 30756167 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 21991740 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21991740 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18926729 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 18926729 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10850391 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 27863843 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27863843 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26119263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8471592 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 8471592 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8471592 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 8471592 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3042354 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3042354 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29220114 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 25553110 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 21614492 — Biomarker: HTR2C mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2C; HTR1C
Study 21614492 — Biomarker: HTR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2A; HTR2
Study 21614492 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 21614492 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 21614492 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 16584354 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 16584354 — Biomarker: MARCKSL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARCKSL1; MLP; MRP
Study 20542811 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 27734257 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 27734257 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11235144 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 11235144 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2537561 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2248385 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2248385 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30461542 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25982143 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25982143 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10063307 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10063307 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 8803516 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8803516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8803516 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 8803516 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28072888 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 23771840 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17623958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11157376 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11157376 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11157376 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11157376 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15769980 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15769980 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15769980 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 15769980 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15769980 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7949088 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 11317156 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 7711427 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7711427 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31221941 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31221941 — Biomarker: CXCL16 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL16; SCYB16; SRPSOX; UNQ2759/PRO6714
Study 28687477 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 28687477 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 21178123 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27560168 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 27560168 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27560168 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 27560168 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 27560168 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 27560168 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27560168 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 23561603 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 11136293 — Biomarker: KSR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KSR1; KSR
Study 22414228 — Biomarker: KCNQ1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNQ1; KCNA8; KCNA9; KVLQT1
Study 10894282 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29241383 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21927922 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21029199 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10968433 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1453199 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 4095819 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4095819 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 19957087 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2086017 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 28470952 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 11558289 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 20823381 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12970007 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10381159 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6134671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20173678 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20173678 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10325782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29759944 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 8393895 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23946472 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 18325461 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11776204 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 11776204 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11776204 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 1631944 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3159468 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29446654 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 18628697 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 12794414 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 28605472 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 6695766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19120715 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 19120715 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19120715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16296712 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16296712 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7211775 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30503386 — Biomarker: UGT2B17 mRNA
Type: Predictive Biomarker (PRD)
Genes: UGT2B17
Study 21724350 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 10204584 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8863869 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 28967554 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 6094076 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6094076 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8890204 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30618054 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 27782851 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 28052588 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15596567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15596567 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15596567 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25937373 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 25937373 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 25937373 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 21414125 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 11853284 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 30088558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26881073 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 12699447 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12699447 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 12699447 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9360565 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21362527 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 14657064 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8713784 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 8713784 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15954962 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10608204 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 31269786 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24016566 — Biomarker: miR-15a
Type: Safety Biomarker (SAF)
Genes: MIR15A
Study 24016566 — Biomarker: miR-16
Type: Safety Biomarker (SAF)
Study 21632446 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21632446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17062774 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17062774 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2589355 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11085201 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 11085201 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 11085201 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 21789517 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18161933 — Biomarker: ADAM17 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM17; CSVP; TACE
Study 11938776 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1285244 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 1285244 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31254226 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 27075914 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20347681 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 7539270 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26303700 — Biomarker: HTR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2A; HTR2
Study 26303700 — Biomarker: HTR2C mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2C; HTR1C
Study 26303700 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 26303700 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 26303700 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 24415640 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 24415640 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 24415640 — Biomarker: BIRC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BIRC3; API2; MIHC; RNF49
Study 26084292 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26084292 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 26084292 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 26084292 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 24011142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21943032 — Biomarker: DCT mRNA
Type: Predictive Biomarker (PRD)
Genes: DCT; TYRP2
Study 21949699 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7800211 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 7800211 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 23644179 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23644179 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17218378 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11319712 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3508327 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28294471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18248107 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14978133 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 10768243 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 22788576 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29330573 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 21523723 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 19907042 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19907042 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20197015 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20197015 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16899775 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1291703 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29167351 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 17318648 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 8061173 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 3288467 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26169969 — Biomarker: SPARC mRNA
Type: Predictive Biomarker (PRD)
Genes: SPARC; ON
Study 21240870 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18048424 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16982453 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 9205026 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7525886 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2455150 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19302707 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 9579257 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 8683829 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12471719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2617169 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 26597925 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24609919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19369056 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19369056 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16306196 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16306196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12693434 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 10099034 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25701338 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 25701338 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 20617051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14620099 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 16129716 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28404133 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 21631949 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 21631949 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9148651 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 5309529 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 20805762 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18080339 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11113407 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 29112459 — Biomarker: ENPP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ENPP2; ATX; PDNP2