AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 27206386 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 2472515 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 2472515 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15492131 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11566622 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11566622 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 29995697 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23696687 — Biomarker: PLA1A mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA1A; NMD; PSPLA1
Study 19507268 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 9648550 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 4396186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4396186 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28679449 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 28679449 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26596672 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23808999 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23808999 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29180454 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29180454 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19712933 — Biomarker: LRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LRP1; A2MR; APR
Study 19712933 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 19712933 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 19712933 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 17938573 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 31812487 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 26342731 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8018001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25105284 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24820145 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11306154 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20921430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15854167 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12878616 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10235439 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 10235439 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8909067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30160043 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22318996 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 22318996 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27430941 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27430941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18778469 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16171525 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16171525 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19623188 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1387500 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1387500 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29613826 — Biomarker: HBEGF mRNA
Type: Predictive Biomarker (PRD)
Genes: HBEGF; DTR; DTS; HEGFL
Study 24485487 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22894958 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 17662087 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 17662087 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15761089 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23640485 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 23640485 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15234287 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 11576883 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 11576883 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11576883 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11576883 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11576883 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31654593 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26100988 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19347770 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 10550466 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2081141 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22613545 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 22613545 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 22613545 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17274711 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 22996743 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22192583 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14674905 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 28131423 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27318344 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 27318344 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12527544 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 28185274 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 24496201 — Biomarker: Complement factor D
Type: Safety Biomarker (SAF)
Genes: CFD; DF; PFD
Study 18356552 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18356552 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 17162709 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10445623 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 2347116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2347116 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31980448 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15794385 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 12425728 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12425728 — Biomarker: Plasma sitosterol and campesterol
Type: Surrogate Endpoint (SUR)
Study 9928724 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24590773 — Biomarker: CYP19A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 19886838 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 28926855 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 26805750 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 8354735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26909786 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26909786 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26909786 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 21055963 — Biomarker: CARD16 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARD16; COP; COP1
Study 12627041 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 30427246 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25499536 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 23466709 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19685113 — Biomarker: RRAD mRNA
Type: Predictive Biomarker (PRD)
Genes: RRAD; RAD
Study 11376827 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11376827 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 23216900 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 21249489 — Biomarker: VPS13C mRNA
Type: Predictive Biomarker (PRD)
Genes: VPS13C; KIAA1421
Study 21249489 — Biomarker: C2CD4A mRNA
Type: Predictive Biomarker (PRD)
Genes: C2CD4A; FAM148A; NLF1
Study 21249489 — Biomarker: C2CD4B mRNA
Type: Predictive Biomarker (PRD)
Genes: C2CD4B; FAM148B; NLF2
Study 8959423 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1525903 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 30244288 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30244288 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 15752881 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 2404052 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23559402 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 23559402 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 23559402 — Biomarker: GSTM3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM3; GST5
Study 23559402 — Biomarker: GRIN2B mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIN2B; NMDAR2B
Study 23559402 — Biomarker: HTR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2A; HTR2
Study 23559402 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 23559402 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 23559402 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 29703289 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 11920355 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 20536946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7675936 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 7675936 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 23975474 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19535242 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28640168 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 21295742 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15278681 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 15278681 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15278681 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10030393 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 26471236 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15068719 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15068719 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17346524 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9756115 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 7848600 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7848600 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 8573993 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 791564 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30734702 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20460257 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 14621036 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31599200 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 24511017 — Biomarker: YAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: YAP1; YAP65
Study 22219013 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 16283062 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6352951 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26946735 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 9294113 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24496312 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 3285485 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 3285485 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 31257177 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31257177 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 22980307 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 22980307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20195181 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9935020 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29195602 — Biomarker: HFE mRNA
Type: Predictive Biomarker (PRD)
Genes: HFE; HLAH
Study 24381278 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 17449580 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 17449580 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8814495 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19332493 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 14711459 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 29294154 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 14760090 — Biomarker: CCR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 9923580 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8087824 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 30508863 — Biomarker: KIR2DS4 mRNA
Type: Predictive Biomarker (PRD)
Genes: KIR2DS4; CD158I; KKA3; NKAT8
Study 30508863 — Biomarker: KIR3DL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KIR3DL1; CD158E; NKAT3; NKB1
Study 28202885 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17900783 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 15120509 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 15120509 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 15120509 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 15120509 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10204813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25881079 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 25881079 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 21435103 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 14762367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15464318 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9849693 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9849693 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 7889637 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 26625194 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 17115389 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15518603 — Biomarker: TFG mRNA
Type: Predictive Biomarker (PRD)
Genes: TFG
Study 31216210 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 21536090 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19499294 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 3535012 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 3535012 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 26046585 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25013997 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18474811 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 18474811 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18474811 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 18474811 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8869862 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 19864243 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 16979857 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11682380 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2835195 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2835195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26245216 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30791871 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 28236978 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 28236978 — Biomarker: HRG mRNA
Type: Predictive Biomarker (PRD)
Genes: HRG
Study 23089999 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8523053 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26510851 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 19218306 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19218306 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7851592 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 31711752 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23303903 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 7742745 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 30707360 — Biomarker: HRC mRNA
Type: Predictive Biomarker (PRD)
Genes: HRC; HCP
Study 24644139 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17942381 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31740722 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28471973 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 23264555 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 19943976 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 9393270 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24730354 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22502790 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 22502790 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12846760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22752379 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 15167592 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 15167592 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11411734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)