AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24186676 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23039824 — Biomarker: RANGAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RANGAP1; KIAA1835; SD
Study 23039824 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 23039824 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23039824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22338468 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 19444516 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 14745141 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 3297471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30625094 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 25710287 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 18394495 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 15292740 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 11315234 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31331265 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 28380313 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28380313 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 9505772 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 22537244 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15751775 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30935524 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27543374 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 25070319 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31357887 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31357887 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24692082 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 20175427 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10822073 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 10822073 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10822073 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 10822073 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15610250 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15610250 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11939936 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 24340926 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18710817 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 24225450 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24225450 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 24225450 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 22101910 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 15983958 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 14763035 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14763035 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20581660 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 20581660 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 20581660 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 20581660 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17295794 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 17295794 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17295794 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 17295794 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 12602413 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 8746877 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7094200 — Biomarker: MERTK mRNA
Type: Predictive Biomarker (PRD)
Genes: MERTK; MER
Study 20872194 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9426077 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 29280940 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29280940 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23887656 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19878195 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 8881668 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 27088635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25295737 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25295737 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12753317 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12753317 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12753317 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12753317 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 1900575 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 6823860 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29746446 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28514618 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17000789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17000789 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8993489 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 24739766 — Biomarker: CASQ1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CASQ1; CASQ
Study 31583738 — Biomarker: FMOD mRNA
Type: Predictive Biomarker (PRD)
Genes: FMOD; FM; SLRR2E
Study 27793396 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11144995 — Biomarker: RFC1
Type: Safety Biomarker (SAF)
Genes: A1; PO-GA; RFC140; MHCBFB
Study 30899994 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19841760 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 1498073 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 10023125 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 31646460 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29447379 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 25601896 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20544489 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20544489 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17953631 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 12555375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23231777 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2121150 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2121150 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19433812 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11769816 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3076140 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27997282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27997282 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23669822 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 18042591 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9386902 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24564262 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22398072 — Biomarker: CTLA4
Type: Predictive Biomarker (PRD)
Genes: CD152; CD; GSE; CTLA-4
Study 12461494 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 1696795 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31772506 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 11763107 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11763107 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31415827 — Biomarker: OXTR mRNA
Type: Predictive Biomarker (PRD)
Genes: OXTR
Study 25023433 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study 21786187 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8466895 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26610430 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 25445074 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 17323071 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 29529222 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23985706 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23985706 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23985706 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23985706 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28724365 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 28724365 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 18332063 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21342915 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15094401 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9749163 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28314838 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 28314838 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 17636399 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27180107 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 24595629 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30777526 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30777526 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30777526 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30777526 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 22337244 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21979989 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21979989 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 21979989 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 21979989 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 21979989 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 16581422 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 6669632 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28645934 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 28645934 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24002511 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24002511 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24002511 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 7827349 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 26578409 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21123462 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16782488 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8131529 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2683789 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 2683789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2683789 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28109128 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 798576 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 30918121 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 16984699 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7752180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28864689 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17500020 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17500020 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15012690 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11058789 — Biomarker: A2M mRNA
Type: Predictive Biomarker (PRD)
Genes: A2M; CPAMD5; FWP007
Study 11058789 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 3578970 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27874837 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24553973 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20448541 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 31222771 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19168461 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 26700275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17466972 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 17466972 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 9576406 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9576406 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9576406 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7935702 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1592715 — Biomarker: OGT mRNA
Type: Predictive Biomarker (PRD)
Genes: OGT
Study 29636247 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26260216 — Biomarker: FMOD mRNA
Type: Predictive Biomarker (PRD)
Genes: FMOD; FM; SLRR2E
Study 21651447 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10559769 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 7576669 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2156277 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 21762225 — Biomarker: CCR3 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CCR3; CMKBR3
Study 21762225 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 11230791 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11230791 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21079818 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21079818 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21079818 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10340790 — Biomarker: HLA-DQB1
Type: Safety Biomarker (SAF)
Genes: IDDM1; CELIAC1
Study 10340790 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 1701714 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 31800000 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31800000 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28400487 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 24165392 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 15089820 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9104896 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29660351 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31986290 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25193793 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8806006 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8806006 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22440372 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16376748 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 8719263 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8719263 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 28224720 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22782640 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24368354 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27302626 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 27302626 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11810082 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30138014 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 11668378 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30064455 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 30064455 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21349184 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18469276 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18469276 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25935875 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 25935875 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 25935875 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 25935875 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 25935875 — Biomarker: UGT2B7 mRNA
Type: Predictive Biomarker (PRD)
Genes: UGT2B7; UGTB2B9
Study 18388897 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16864174 — Biomarker: TOP2A mRNA
Type: Predictive Biomarker (PRD)
Genes: TOP2A; TOP2
Study 16864174 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12356187 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 12356187 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7016781 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2523493 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 25495748 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21131132 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 21131132 — Biomarker: ADGRE5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADGRE5; CD97
Study 15259389 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 15016643 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 15016643 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9439537 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 22188544 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 20159820 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 7555486 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25943532 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 14615732 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 7799046 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21239636 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21239636 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5