AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 9502783 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 1662578 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 27930386 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 27341466 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 28339139 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 23232805 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 11225504 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 9433396 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22103994 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17723312 — Biomarker: FMOD mRNA
Type: Predictive Biomarker (PRD)
Genes: FMOD; FM; SLRR2E
Study 1942779 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1942779 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 26639039 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 25127483 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19683936 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 2661155 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 21590281 — Biomarker: Auditory mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 21590281 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 15298758 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15298758 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28590364 — Biomarker: Auditory mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 28590364 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 16880425 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 1340835 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 20151053 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20151053 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17702967 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 11897771 — Biomarker: EDNRA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDNRA; ETA; ETRA
Study 11897771 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10204835 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12172328 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 12172328 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 12172328 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12685875 — Biomarker: GAD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD2; GAD65
Study 30183453 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 9589379 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29191136 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26714972 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 21287417 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16645371 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 10971787 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 10971787 — Biomarker: PLTP mRNA
Type: Predictive Biomarker (PRD)
Genes: PLTP
Study 10971787 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 10971787 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 10971787 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 1727841 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29257795 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29257795 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29257795 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24571483 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17717914 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11057105 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31842189 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31842189 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24434301 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24434301 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21890323 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30033781 — Biomarker: TTN mRNA
Type: Predictive Biomarker (PRD)
Genes: TTN
Study 28105513 — Biomarker: GK mRNA
Type: Predictive Biomarker (PRD)
Genes: GK
Study 28105513 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 23903772 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19826309 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 19826309 — Biomarker: CDKN1B mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN1B; KIP1; p27
Study 19826309 — Biomarker: MYF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYF5; BHLHC2
Study 12768357 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 12768357 — Biomarker: FXYD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FXYD1; PLM
Study 10671905 — Biomarker: LARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LARS1; KIAA1352; LARS
Study 29656744 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 25228778 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study 25228778 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25228778 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31440895 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 27173517 — Biomarker: miR-135b
Type: Predictive Biomarker (PRD)
Genes: MIR135B
Study 27173517 — Biomarker: miR-183-5p
Type: Safety Biomarker (SAF)
Genes: MIR183
Study 27173517 — Biomarker: miR-183
Type: Safety Biomarker (SAF)
Genes: MIR183
Study 27173517 — Biomarker: miR-182-5p
Type: Safety Biomarker (SAF)
Genes: MIR182
Study 27173517 — Biomarker: miR-133a
Type: Safety Biomarker (SAF)
Study 27173517 — Biomarker: miR-145
Type: Predictive Biomarker (PRD)
Genes: MIR145
Study 27173517 — Biomarker: miR-30c
Type: Safety Biomarker (SAF)
Study 24169612 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21159499 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17077374 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 10827391 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22533659 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19018483 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 15671799 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15671799 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8681637 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8681637 — Biomarker: Interleukin 1 alpha
Type: Safety Biomarker (SAF)
Genes: IL1A; IL1F1
Study 8681637 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 27014997 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24613784 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 8310980 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2647846 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2647846 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28241386 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 15039504 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26499921 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26499921 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22900702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10640625 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 3799505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31514854 — Biomarker: NSMAF mRNA
Type: Predictive Biomarker (PRD)
Genes: NSMAF; FAN
Study 27884120 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27884120 — Biomarker: F7 mRNA
Type: Predictive Biomarker (PRD)
Genes: F7
Study 27146725 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23639047 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 19948873 — Biomarker: SLC12A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC12A3; NCC; TSC
Study 11126178 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 11126178 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 8648207 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1346562 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20179259 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20179259 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17688921 — Biomarker: UBC mRNA
Type: Predictive Biomarker (PRD)
Genes: UBC
Study 6106828 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28317828 — Biomarker: CPD mRNA
Type: Predictive Biomarker (PRD)
Genes: CPD
Study 21453706 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 16330466 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15469418 — Biomarker: APOB mRNA
Type: Predictive Biomarker (PRD)
Genes: APOB
Study 15469418 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 29073803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19826112 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 9859076 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 7631301 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31125767 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 18471914 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15563708 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24457412 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 24457412 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 24457412 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 24457412 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22057424 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 22057424 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 22057424 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 21200103 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17374316 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 15838685 — Biomarker: HLA-DQB1
Type: Safety Biomarker (SAF)
Genes: IDDM1; CELIAC1
Study 12181364 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study 12181364 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10460557 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31028057 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 15798963 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16678648 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 28436380 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 20133263 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20133263 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 8908676 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 23525950 — Biomarker: FCER1A mRNA
Type: Predictive Biomarker (PRD)
Genes: FCER1A; FCE1A
Study 23525950 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 23525950 — Biomarker: ADAM33 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM33; C20orf153; UNQ873/PRO1891
Study 23525950 — Biomarker: NANOS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS1; NOS1
Study 23525950 — Biomarker: Interleukin 4 receptor alpha
Type: Predictive Biomarker (PRD)
Genes: IL4R; IL4RA; 582J2.1
Study 19687165 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15523321 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 8279987 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27912106 — Biomarker: LTB4R mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 19828899 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19828899 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2533803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28631933 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11061732 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22913550 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16428086 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16428086 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14659379 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1688989 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11798649 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 1826883 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 1826883 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20576162 — Biomarker: SP9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP9
Study 18775266 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 11782036 — Biomarker: ETV6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV6; TEL; TEL1
Study 11782036 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30764699 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26267985 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17280678 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17280678 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 3284271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12709737 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16298597 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16298597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18211118 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26295966 — Biomarker: TTN mRNA
Type: Predictive Biomarker (PRD)
Genes: TTN
Study 21090831 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21090831 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10575333 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 6125625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28379623 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28379623 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24408122 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25666417 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15466766 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21511523 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 26233335 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16763748 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29304065 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 23093337 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23093337 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20019087 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 18594001 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17189542 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 6322985 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31396667 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 30611996 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 30611996 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 30611996 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 30611996 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 30611996 — Biomarker: MAPK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK1; ERK2; PRKM1; PRKM2
Study 22805422 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22805422 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11696462 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 11696462 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 7870845 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 2975951 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 2975951 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28822719 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28822719 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28822719 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 18840107 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14638544 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14638544 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20082754 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20082754 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2467117 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12576167 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 20540635 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2337713 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2337713 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25056413 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 25056413 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 7944879 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 29178685 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 21872708 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 9701188 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 9701188 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9701188 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9701188 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9701188 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 28062311 — Biomarker: TRPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPA1; ANKTM1
Study 28062311 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 16224198 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 31077425 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 27904905 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 2679864 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22867815 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22867815 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 20624673 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19175374 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2026743 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI