AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04570410 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03170206 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT00219180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01106781 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04837391 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT02615301 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01607021 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study NCT02410148 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01433523 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT02558270 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT02847533 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT02259231 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT00567931 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study NCT04412499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03728244 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT02589431 — Biomarker: STC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STC1; STC
Study NCT02589431 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT03119649 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study NCT03975543 — Biomarker: PDE6B mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE6B; PDEB
Study NCT04387656 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT06339554 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT01583439 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00585091 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study NCT02639676 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04489420 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT02278705 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00036374 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02628340 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study NCT00319449 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03327688 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT03423706 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT03423706 — Biomarker: CARTPT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CARTPT; CART
Study NCT03423706 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT00149175 — Biomarker: Amyloid beta peptide (1-40)
Type: Pharmacodynamic Biomarker (PDY)
Genes: APP; A4; AD1
Study NCT00149175 — Biomarker: PSEN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSEN1; AD3; PS1; PSNL1
Study NCT00149175 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT00674219 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study NCT02867800 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study NCT02209779 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03665155 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study NCT00141583 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study NCT00141583 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT00141583 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03636698 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study NCT03636698 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study NCT03636698 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study NCT03636698 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT04277195 — Biomarker: SPAG5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPAG5
Study NCT00708929 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study NCT01445054 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03051880 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03051880 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00042952 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study NCT00155844 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study NCT00155844 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study NCT00114361 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT02842814 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study NCT03157557 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02054546 — Biomarker: IGFBP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP7; MAC25; PSF
Study NCT05469087 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01264627 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00534417 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT04424914 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study NCT05366608 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02693964 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02528695 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study NCT02924805 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02466529 — Biomarker: Survival motor neuron protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT01608191 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT04553887 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02831530 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study NCT02831530 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT00254397 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT01980446 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00394745 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01175889 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT04137614 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04152343 — Biomarker: PGP mRNA
Type: Predictive Biomarker (PRD)
Genes: PGP
Study NCT02813538 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00377962 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT01905215 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT00672113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00634270 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study NCT04948086 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study NCT00608465 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01663077 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study NCT01663077 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT01663077 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study NCT01663077 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study NCT00001427 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT02132741 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04405206 — Biomarker: MYRF mRNA
Type: Predictive Biomarker (PRD)
Genes: MYRF; C11orf9; KIAA0954; MRF
Study NCT03280537 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT01671384 — Biomarker: Survival motor neuron protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT01671384 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04823000 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT02323360 — Biomarker: ADAM17 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM17; CSVP; TACE
Study NCT02280083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01614457 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study NCT00283829 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT01380899 — Biomarker: Synuclein alpha
Type: Pharmacodynamic Biomarker (PDY)
Genes: SNCA; NACP; PARK1
Study NCT03876522 — Biomarker: ZFYVE9 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZFYVE9; MADHIP; SARA; SMADIP
Study NCT04089098 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study NCT02308111 — Biomarker: NR1H4 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT03583463 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT03583463 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03583463 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT03583463 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00121407 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT04576338 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02296879 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT02296879 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study NCT03410043 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01836315 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01836315 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study NCT00421447 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03185598 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00728338 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03331211 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study NCT01983098 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study NCT01983098 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study NCT04723836 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study NCT04723836 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00783289 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study NCT04665193 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT01960686 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT03177252 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03150121 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT03131999 — Biomarker: TSC2
Type: Predictive Biomarker (PRD)
Genes: tuberin; LAM; PPP1R160
Study NCT00368368 — Biomarker: GK mRNA
Type: Predictive Biomarker (PRD)
Genes: GK
Study NCT01815567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01903759 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00106977 — Biomarker: FGFR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR3; JTK4
Study NCT00106977 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00460356 — Biomarker: MAPK8IP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK8IP2; IB2; JIP2; PRKM8IPL
Study NCT03885466 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01978366 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study NCT01789918 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04331197 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT00410566 — Biomarker: SMPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMPD1; ASM
Study NCT00170924 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03195296 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT02218177 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00801671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01578499 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study NCT00793923 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT04595955 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT04595955 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT03707093 — Biomarker: TNFRSF9 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF9; CD137; ILA
Study NCT03580057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03842709 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT03842709 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03842709 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study NCT03842709 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study NCT00756964 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study NCT02628769 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study NCT02628769 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study NCT04975048 — Biomarker: SREBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SREBF1; BHLHD1; SREBP1
Study NCT04975048 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00704106 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT00893711 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study NCT00893711 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study NCT04321863 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00395538 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study NCT02286089 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study NCT02026388 — Biomarker: APRT mRNA
Type: Predictive Biomarker (PRD)
Genes: APRT
Study NCT00815971 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00815971 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03431935 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00877097 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02791152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03784924 — Biomarker: TMPRSS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMPRSS2; PRSS10
Study NCT01568411 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT02038478 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT00341601 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study NCT00341601 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study NCT02086279 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT01723787 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00224406 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study NCT02389374 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study NCT04144218 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT01137136 — Biomarker: CYP19A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP19A1; ARO1; CYAR; CYP19
Study NCT03681184 — Biomarker: PHC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PHC1; EDR1; PH1
Study NCT01418560 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT00463073 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00463073 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT00706849 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01382511 — Biomarker: STAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT1
Study NCT04103918 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT00770861 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01412242 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT01867073 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study NCT00682968 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02464319 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT02263664 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT00816218 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02095431 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT01773395 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01931176 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT05760625 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT05760625 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT03042702 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study NCT01124630 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study NCT01992159 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01146210 — Biomarker: FANCD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FANCD2; FACD
Study NCT03700710 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00376428 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study NCT00613847 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02977884 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04368052 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study NCT02155803 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study NCT02300376 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study NCT04292574 — Biomarker: Survival motor neuron protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT04330300 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT04100655 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT02528617 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01650467 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT04255134 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02693184 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03063632 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT02474355 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02474355 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT04618887 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study NCT02271490 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study NCT03435900 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT02119130 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04582227 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01783405 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study NCT01914133 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02042105 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT03722290 — Biomarker: FMR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMR1
Study NCT03722290 — Biomarker: EIF4E mRNA
Type: Predictive Biomarker (PRD)
Genes: EIF4E; EIF4EL1; EIF4F
Study NCT03722290 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study NCT03722290 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02034136 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00857610 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF