AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31512143 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28223262 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 23662815 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 19473560 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17636114 — Biomarker: SLC2A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A2; GLUT2
Study 17636114 — Biomarker: ABCC8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC8; HRINS; SUR; SUR1
Study 12374678 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 12374678 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 10075594 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 10075594 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30951917 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 19763132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17088140 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 11349183 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 18608042 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 12358335 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 7572651 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7572651 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31797310 — Biomarker: IGFBP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP7; MAC25; PSF
Study 27415612 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 27415612 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 22442826 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 18508290 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 10979946 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8774389 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12797909 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30310979 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27386642 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27386642 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22681643 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9729596 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24265819 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21943318 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 17136943 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 10877734 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 20981001 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 15701465 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15701465 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19560257 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 15001970 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 15001970 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 3544754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11156732 — Biomarker: RAPGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 30871934 — Biomarker: NES mRNA
Type: Predictive Biomarker (PRD)
Genes: NES; Nbla00170
Study 21940789 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2202247 — Biomarker: Nasal potential difference
Type: Pharmacodynamic Biomarker (PDY)
Study 25468506 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 22267336 — Biomarker: IGF2R mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF2R; MPRI
Study 11813228 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 31074115 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 23801589 — Biomarker: PICALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PICALM; CALM
Study 325301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28056936 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 24692821 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15670788 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 12765846 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 12765846 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 10580781 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 10580781 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10580781 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2366533 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 39387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20014653 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 27039242 — Biomarker: Alpha-1-acid glycoprotein 1
Type: Monitoring Biomarker (MOI)
Genes: ORM1; AGP1
Study 24683583 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 24683583 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 1462581 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25263326 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9739036 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21084796 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 8912545 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 31782408 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31782408 — Biomarker: Heart fatty acid-binding protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FABP3; FABP11; MDGI
Study 31782408 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31782408 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31782408 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31782408 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 31782408 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 24732714 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24732714 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19608684 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 19608684 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 10798801 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 10798801 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 1676117 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16433247 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8546552 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6196821 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 6196821 — Biomarker: SPINK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPINK1; PSTI
Study 25311633 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21038647 — Biomarker: TFG mRNA
Type: Predictive Biomarker (PRD)
Genes: TFG
Study 12140351 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 12140351 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12140351 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22950654 — Biomarker: DGAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DGAT1; AGRP1; DGAT
Study 18854568 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 8869864 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8869864 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1504052 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30818032 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 30818032 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30818032 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 30818032 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 29324303 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 27871510 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 27871510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19852540 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 18395326 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 16164192 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 16164192 — Biomarker: Dihydrothymine dehydrogenase
Type: Safety Biomarker (SAF)
Genes: DPYD
Study 16164192 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 12749519 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26758039 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7776913 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27066188 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 27066188 — Biomarker: MTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 27066188 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17996511 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15743365 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 7174 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25156269 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25156269 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 21842996 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1909152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31132509 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 23713294 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23713294 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23713294 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21606263 — Biomarker: FBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBP1; FBP
Study 15042546 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15042546 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15042546 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15042546 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15042546 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 19531591 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28940312 — Biomarker: TRIM32 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM32; HT2A
Study 10857970 — Biomarker: HGD mRNA
Type: Predictive Biomarker (PRD)
Genes: HGD; HGO
Study 9120161 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 26762911 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 29584458 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23220077 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17018708 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16326641 — Biomarker: PALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PALM; KIAA0270
Study 7597662 — Biomarker: DDR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 31958907 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15495826 — Biomarker: CXCL13 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL13; BCA1; BLC; SCYB13
Study 28864691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23195627 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 13679934 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8612107 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1595324 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 6096282 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29454678 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29454678 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29454678 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25426516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19372358 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 27594150 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 25751697 — Biomarker: Auditory steady-state response
Type: Pharmacodynamic Biomarker (PDY)
Study 3524176 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30182113 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 30182113 — Biomarker: BPIFA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BPIFA2; C20orf70; SPLUNC2; UNQ510/PRO1025
Study 1543618 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25224018 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 17997263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12525339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31602965 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23569986 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12569793 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12569793 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 30596978 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 28060206 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 21353329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17544338 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 15163331 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15163331 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28019686 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24277400 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11223449 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10443648 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 10443648 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10443648 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 23446897 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 20876346 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 20876346 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 28796313 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28796313 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21448304 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9156357 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3605732 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3605732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18752856 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 10198901 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 25824533 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 11727293 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 21038649 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 17058826 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 6424997 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31516127 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10613424 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 25440797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12868045 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7491378 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 8886414 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 8886414 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1860682 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 22664804 — Biomarker: ESD mRNA
Type: Predictive Biomarker (PRD)
Genes: ESD
Study 20857772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30395021 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 30395021 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19787388 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19787388 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19787388 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17520260 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 9349604 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26899387 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2702989 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27332770 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 17391565 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 10511135 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 10511135 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 7910207 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28929359 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24674384 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 24674384 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 22719796 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18417517 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12002290 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12002290 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12002290 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12002290 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 12002290 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 7754792 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25471273 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 9270561 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17209328 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17209328 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 8967882 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26568032 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 16078036 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 12494080 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10367046 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7499031 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2