AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 8515787 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26079223 — Biomarker: Lysosomal alpha-glucosidase
Type: Safety Biomarker (SAF)
Genes: GAA
Study 19167636 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 29528117 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2919766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24187862 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 24187862 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25708022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21632496 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2187327 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23479454 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 21696889 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 19404631 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 21788624 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8040674 — Biomarker: STUB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STUB1; CHIP; PP1131
Study 2522265 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2522265 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 2522265 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 16896939 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 10770452 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 24964358 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 24964358 — Biomarker: GSS mRNA
Type: Predictive Biomarker (PRD)
Genes: GSS
Study 2959232 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28755054 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 30122646 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 18042655 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 31115626 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 23553187 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23977105 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 20537762 — Biomarker: SPAG9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPAG9; HSS; KIAA0516; MAPK8IP4; SYD1; HLC6
Study 19440013 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 7523909 — Biomarker: Hypoxanthine-guanine phosphoribosyltransferase
Type: Safety Biomarker (SAF)
Genes: HPRT1; HPRT
Study 26714845 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11763829 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8529054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31655626 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 9100602 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 9100602 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9100602 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 9100602 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2516705 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 31327753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16840826 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8324945 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 3462459 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16095461 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 16095461 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16095461 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12403958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28782697 — Biomarker: VCP mRNA
Type: Predictive Biomarker (PRD)
Genes: VCP
Study 21600592 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21600592 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15267123 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11158861 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11158861 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11158861 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11158861 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 3103540 — Biomarker: TAOK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 27492018 — Biomarker: PLB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLB1; PLB
Study 16494857 — Biomarker: Complement factor D
Type: Safety Biomarker (SAF)
Genes: CFD; DF; PFD
Study 15259901 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9298779 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 9298779 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 9298779 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9298779 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 7899804 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25012543 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25012543 — Biomarker: EPAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPAS1; BHLHE73; HIF2A; MOP2; PASD2
Study 25012543 — Biomarker: CXCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR1; CMKAR1; IL8RA
Study 25012543 — Biomarker: VHL mRNA
Type: Predictive Biomarker (PRD)
Genes: VHL
Study 25012543 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20361904 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 19368096 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 19368096 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30321061 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 29961161 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29961161 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24652989 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 24652989 — Biomarker: NOTCH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOTCH1; TAN1
Study 21410035 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12914870 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12914870 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 12914870 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 10340366 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 10340366 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 30193295 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30193295 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 24126365 — Biomarker: DNA repair endonuclease XPF
Type: Predictive Biomarker (PRD)
Genes: ERCC4; ERCC11; XPF
Study 19399391 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17415036 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15157254 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study 16492007 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6653649 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31849296 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31849296 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27581760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21878834 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 17043157 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17043157 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17043157 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 17043157 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12959319 — Biomarker: PSD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSD4; EFA6B; TIC
Study 27513278 — Biomarker: TSC2
Type: Predictive Biomarker (PRD)
Genes: tuberin; LAM; PPP1R160
Study 27513278 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25479899 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22414053 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10350664 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27583404 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20565725 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 14607735 — Biomarker: MALT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MALT1; MLT
Study 7485886 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31492516 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 29425477 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29425477 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12519875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12519875 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9169959 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 29769133 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 29959105 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 26999243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26999243 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10226770 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10741622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9015467 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9015467 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1999932 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24931840 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 22735900 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 10203111 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 21421179 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18235907 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24090685 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 15974900 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8738693 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30859428 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16680620 — Biomarker: ELK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELK3; NET; SAP2
Study 29921318 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20033075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9465842 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 181978 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 31200043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21489699 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 11063156 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9067278 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 21909151 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16905783 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7964952 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 25539791 — Biomarker: HTR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2A; HTR2
Study 18455517 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 12717099 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 31600365 — Biomarker: TPI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPI1; TPI
Study 26682789 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11943936 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 7844609 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 7844609 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7844609 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 29324935 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 9605677 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28993451 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29067867 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 24461315 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 24461315 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8577941 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9096189 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9096189 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17664049 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23524197 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16894335 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11702035 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9143783 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3597738 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19853417 — Biomarker: MYRF mRNA
Type: Predictive Biomarker (PRD)
Genes: MYRF; C11orf9; KIAA0954; MRF
Study 9462474 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 9462474 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study 26460504 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 26460504 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26460504 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22739371 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22739371 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 22739371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22739371 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 22739371 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 22226132 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 30846465 — Biomarker: TSC2
Type: Predictive Biomarker (PRD)
Genes: tuberin; LAM; PPP1R160
Study 30846465 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26786346 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11287373 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 2873966 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12971634 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 19147504 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17971178 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17971178 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28662296 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 26134371 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 12499335 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12499335 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11004144 — Biomarker: CPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPB1; CPB; PCPB
Study 31187045 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31187045 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28942334 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 26471432 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 26471432 — Biomarker: CA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA1
Study 26471432 — Biomarker: Synuclein alpha
Type: Pharmacodynamic Biomarker (PDY)
Genes: SNCA; NACP; PARK1
Study 23818758 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8373610 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19670303 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 9738734 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 25715157 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23265571 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19833591 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 19833591 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 17560423 — Biomarker: CTLA4
Type: Predictive Biomarker (PRD)
Genes: CD152; CD; GSE; CTLA-4
Study 12590006 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11794823 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11794823 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7992252 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 7992252 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 7992252 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 7992252 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 4613531 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 19106240 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9647334 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 9647334 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 1825037 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 16187243 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14508352 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31199595 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22440088 — Biomarker: MLLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MLLT3; AF9; YEATS3
Study 22440088 — Biomarker: SGK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SGK1; SGK
Study 15637449 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12359986 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7954561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26714284 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 11502903 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 2442512 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2442512 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 2442512 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28463904 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 19463375 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 19463375 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 19463375 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 19463375 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5