AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 7596131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28656353 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23926207 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20455192 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28752433 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 25252663 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 22980174 — Biomarker: KCNN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNN3; K3
Study 3519043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24603938 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24603938 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 22027793 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22027793 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22027793 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10962123 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 22284900 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12944692 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12944692 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 6628500 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15536455 — Biomarker: GNB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNB3
Study 15536455 — Biomarker: EDNRA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDNRA; ETA; ETRA
Study 15536455 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 2756914 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2756914 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28674135 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 15021967 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 9784903 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9784903 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 9784903 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 7609494 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7609494 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21849660 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 20439556 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 20439556 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17225981 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17225981 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 23047989 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 15010373 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17097955 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17097955 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17097955 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 9578508 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 3376143 — Biomarker: NES mRNA
Type: Predictive Biomarker (PRD)
Genes: NES; Nbla00170
Study 23948125 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17023701 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8719186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31055791 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28950421 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 28950421 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 26083426 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24021938 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28209359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23911216 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21527854 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21527854 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 18854397 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 3529744 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12208703 — Biomarker: ALPI mRNA
Type: Predictive Biomarker (PRD)
Genes: ALPI
Study 8676932 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6175137 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 28186425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19571807 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 19571807 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 12209278 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24780066 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9819068 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 19593890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9456291 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11868797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7639971 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 951455 — Biomarker: DBH mRNA
Type: Predictive Biomarker (PRD)
Genes: DBH
Study 30668163 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25565656 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17182977 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9682660 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 23043888 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 18234290 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 3953366 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22508151 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 18789113 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 16125959 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10091821 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7772081 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7438772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31910903 — Biomarker: miR-223
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR223
Study 30991661 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 14706480 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 31167421 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15156528 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9386869 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26282650 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 12723391 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 27513932 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27513932 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18549857 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12806595 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25243781 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25157406 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18688657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24934915 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19602610 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9645291 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 9645291 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29615070 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study 29615070 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1969252 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31664444 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 29966992 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 20876408 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20876408 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20876408 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11932285 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2692825 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12684211 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 9190129 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3590805 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 25042022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25042022 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31344077 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7924704 — Biomarker: MN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MN1
Study 23104720 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17140167 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17140167 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10771457 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 1425625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26702788 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 23029839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20102879 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 12668861 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 7649753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25557052 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 11141242 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11141242 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 11141242 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 20216098 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 20216098 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 20216098 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20216098 — Biomarker: FOXP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 18594529 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10421591 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 15043519 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9493701 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26668200 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 22055112 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 17452287 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 15561950 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 11772575 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26450920 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 11056590 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24849439 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24849439 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24849439 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 24849439 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24849439 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24849439 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 24849439 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8607315 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28118537 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 21814547 — Biomarker: TCF7L2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCF7L2; TCF4
Study 3823637 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27367159 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15336780 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15336780 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 15336780 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 9565943 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 2780404 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 26472122 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 11757472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9164203 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 9164203 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9164203 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 29864779 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29864779 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29864779 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29864779 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 27583648 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6097457 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11242608 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11242608 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 11242608 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8452386 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 24648266 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20979455 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study 18568841 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8090332 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 8090332 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 30912719 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25933487 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 24156966 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 17014554 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8973780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29099978 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 25767259 — Biomarker: SLC5A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A1; NAGT; SGLT1
Study 25767259 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 25767259 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 1724577 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 1724577 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 12970287 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23530976 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21774100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15268810 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 7805462 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7805462 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7805462 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 11049014 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 9052345 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8305650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23997095 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16583466 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 7830026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23186831 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23186831 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23186831 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 23186831 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9136776 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 9136776 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 8053664 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 31674161 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31674161 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 19110596 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25378931 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 25378931 — Biomarker: FGFR1
Type: Predictive Biomarker (PRD)
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 25378931 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 14687092 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11593067 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7903966 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26405990 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26405990 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26405990 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 26405990 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19744614 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9470059 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9470059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7911029 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29742924 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 26231288 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 26231288 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 21159789 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 21159789 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21159789 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21159789 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3534583 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29941309 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 14682110 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31493361 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27791067 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27791067 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20309434 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20309434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20309434 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6794909 — Biomarker: CAMP mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMP; CAP18; FALL39; HSD26