AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 10759650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1425528 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26818586 — Biomarker: MKNK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MKNK1; MNK1
Study 26818586 — Biomarker: UBTF mRNA
Type: Predictive Biomarker (PRD)
Genes: UBTF; UBF; UBF1
Study 22072492 — Biomarker: Histone acetylation
Type: Pharmacodynamic Biomarker (PDY)
Study 19880433 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31125296 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 21621801 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21621801 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 18993147 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30587441 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 30587441 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 26496309 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 26496309 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2577711 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 11327626 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9594209 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 25465108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9457400 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 21838411 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 21838411 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 19289619 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 11092994 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3533547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20814040 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 9039930 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 2252531 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 25781537 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 25781537 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23348398 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 19567992 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15309461 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7955265 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 7955265 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 29346507 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 25605643 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 14573335 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9220210 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9220210 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8148213 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 31200560 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31200560 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28068001 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 25788001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20818901 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17322430 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16353041 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 16353041 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 16353041 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16353041 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1935475 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 1935475 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 7723338 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30102389 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30102389 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 21285125 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29096833 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 29096833 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29096833 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23537979 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10764680 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8453962 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2429834 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22876730 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 12890374 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 6682324 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29924696 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 17437473 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 2534084 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26165955 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 16557155 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11504315 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7700061 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22972879 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22972879 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20601414 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20601414 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10908771 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 8720610 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 18516070 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 18516070 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 29985652 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20800241 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 20800241 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20800241 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 20800241 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1479106 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 6365838 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20148772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26387692 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26387692 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10495686 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30639231 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30639231 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24622416 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2563317 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 2563317 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25919636 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21771304 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 14982609 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 11467760 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11467760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26380442 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19060449 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 19060449 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31147187 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 31147187 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study 16275368 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 11271221 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11271221 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24968970 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24002501 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 24002501 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 24002501 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 24002501 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8572782 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8572782 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8572782 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 30098049 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 16117978 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 14685054 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14685054 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6613908 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6613908 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31663173 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 29912858 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 29912858 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27343175 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24365194 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15668427 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 10950767 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1477491 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 17696277 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17696277 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16181540 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12057714 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 10816058 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12927929 — Biomarker: EIF2AK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EIF2AK2; PKR; PRKR
Study 10773790 — Biomarker: OTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 9326983 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12393528 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 27075216 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC
Study 27075216 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17898099 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10155673 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 31814226 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 10784360 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 1833529 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28956671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28956671 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24233571 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 10199771 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 29535139 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8750405 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8750405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25835119 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25835119 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25835119 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25835119 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25835119 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24302596 — Biomarker: GAD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD2; GAD65
Study 22357746 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21205122 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 22735306 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20847403 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 25037746 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18394446 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18394446 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 31101617 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 22459616 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11524058 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11524058 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8313933 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 3791867 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 27447483 — Biomarker: PNN mRNA
Type: Predictive Biomarker (PRD)
Genes: PNN; DRS; MEMA
Study 24722495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20978144 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9834039 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 2679473 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25934525 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 24204757 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 15486607 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 14760258 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 27484356 — Biomarker: FGR mRNA
Type: Predictive Biomarker (PRD)
Genes: FGR; SRC2
Study 26216729 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 16894312 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 14680093 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8977677 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8977677 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 6530546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26806217 — Biomarker: AADAC mRNA
Type: Predictive Biomarker (PRD)
Genes: AADAC; DAC
Study 19084683 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17942835 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16187176 — Biomarker: C-C motif chemokine 4
Type: Monitoring Biomarker (MOI)
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 16187176 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 16187176 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 12537187 — Biomarker: CARD16 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARD16; COP; COP1
Study 12537187 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31881986 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31355514 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 31355514 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 24506405 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 13678870 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10809018 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1900443 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 25738784 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 9049526 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9049526 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28253390 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28253390 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28253390 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 25338110 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24482090 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17300593 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 15215794 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15215794 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15215794 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 11149474 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11149474 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11149474 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 30797222 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 23282858 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 17304146 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study 12960682 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8789548 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 23999998 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18448569 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 18448569 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 11002232 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 11002232 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8623886 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31593830 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 20485203 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7590814 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7590814 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7590814 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28796276 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 28796276 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 23146660 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 18505668 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25971920 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)