AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT03039452 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT03344601 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study NCT03460275 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03998930 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study NCT00219739 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT00219739 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT04879316 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00641758 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study NCT02104752 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT00666172 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03344822 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03760055 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT00889408 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT00889408 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study NCT02841267 — Biomarker: Growth/differentiation factor 8
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: MSTN; GDF8
Study NCT04724785 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT02764333 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT02764333 — Biomarker: Folate receptor alpha
Type: Predictive Biomarker (PRD)
Genes: FOLR1; FOLR
Study NCT02161861 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study NCT01025531 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study NCT03570203 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study NCT03709147 — Biomarker: Serine/threonine-protein kinase STK11
Type: Safety Biomarker (SAF)
Genes: STK11
Study NCT03944603 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00967642 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00178217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02146222 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT02146222 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT02146222 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02146222 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT01548859 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study NCT03784261 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02066675 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study NCT02906202 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT02906202 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study NCT03034122 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study NCT03933332 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04348643 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study NCT01080651 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT03214978 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study NCT03214978 — Biomarker: TTN mRNA
Type: Predictive Biomarker (PRD)
Genes: TTN
Study NCT03434574 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01784848 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01050322 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01050322 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02215330 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study NCT04251611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02833350 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00570765 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study NCT01860716 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01860716 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study NCT01860716 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT01648920 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study NCT00090870 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT02437383 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study NCT02284269 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT04137627 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study NCT04137627 — Biomarker: miR-210
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR210
Study NCT01516203 — Biomarker: M. tuberculosis 85B mRNA
Type: Monitoring Biomarker (MOI)
Genes: fbpB; Rv1886c; MTCY180.32
Study NCT02208570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02324972 — Biomarker: INPP5D mRNA
Type: Predictive Biomarker (PRD)
Genes: INPP5D; SHIP; SHIP1
Study NCT00135707 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00135707 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT01232777 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03373071 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT01408901 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT03382418 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT04225013 — Biomarker: PDXP mRNA
Type: Predictive Biomarker (PRD)
Genes: PDXP; CIN; PLP; PLPP
Study NCT04225013 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study NCT00462683 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT04496466 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT02678689 — Biomarker: Tripeptidyl-peptidase I
Type: Predictive Biomarker (PRD)
Genes: TPP1; CLN2; GIG1; UNQ267/PRO304
Study NCT02159716 — Biomarker: CARTPT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CARTPT; CART
Study NCT00421174 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04553770 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04553770 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT04553770 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT03176095 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study NCT03775967 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study NCT02016573 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02389062 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study NCT01517620 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02198872 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT00002773 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT04242420 — Biomarker: GJA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GJA4
Study NCT04242420 — Biomarker: GJA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GJA1; GJAL
Study NCT01977209 — Biomarker: APEX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study NCT01517243 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT00279552 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT03235544 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study NCT03212690 — Biomarker: RAS peptides
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01595633 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT00200577 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT01781754 — Biomarker: UCP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP2; SLC25A8
Study NCT01781754 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT01403571 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT02391792 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03637192 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT04636411 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01424917 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study NCT01564914 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03489148 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00203879 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study NCT02906085 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study NCT01250119 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01250119 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT01788488 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study NCT00227448 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01355562 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT01506258 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT01957774 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study NCT01497431 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT01763827 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03218332 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03048084 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02317484 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT03870100 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02418429 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT04382300 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02391701 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02391701 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02391701 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT02391701 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02835742 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT04525352 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT04525352 — Biomarker: TCIRG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCIRG1; ATP6N1C; ATP6V0A3
Study NCT02811809 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT02811809 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01141673 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study NCT02025322 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00766025 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT04213729 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03653338 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00027807 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01453361 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00098254 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT03323827 — Biomarker: SLC25A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A4; AAC1; ANT1
Study NCT03316417 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT01457573 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study NCT03599388 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04213482 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03609125 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study NCT04806230 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study NCT04806230 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study NCT00890058 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT01570296 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01570296 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study NCT04192513 — Biomarker: DBI mRNA
Type: Predictive Biomarker (PRD)
Genes: DBI
Study NCT03786796 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT03786796 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study NCT03786796 — Biomarker: PALB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PALB2; FANCN
Study NCT03786796 — Biomarker: CHEK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHEK2; CDS1; CHK2; RAD53
Study NCT03786796 — Biomarker: RAD51C mRNA
Type: Predictive Biomarker (PRD)
Genes: RAD51C; RAD51L2
Study NCT03786796 — Biomarker: BARD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BARD1
Study NCT03786796 — Biomarker: CHEK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHEK1; CHK1
Study NCT03786796 — Biomarker: FANCL mRNA
Type: Predictive Biomarker (PRD)
Genes: FANCL; PHF9
Study NCT03786796 — Biomarker: RAD51B mRNA
Type: Predictive Biomarker (PRD)
Genes: RAD51B; RAD51L1; REC2
Study NCT02693119 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study NCT01213446 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study NCT02051842 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT03333304 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study NCT00087789 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study NCT04482907 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study NCT04482907 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04482907 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study NCT00932126 — Biomarker: PAK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAK4; KIAA1142
Study NCT00066365 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT03944031 — Biomarker: Beta-N-acetylhexosaminidase
Type: Safety Biomarker (SAF)
Genes: OGA; HEXC; KIAA0679; MEA5; MGEA5
Study NCT03977584 — Biomarker: PSEN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSEN1; AD3; PS1; PSNL1
Study NCT03977584 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03344133 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study NCT03344133 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT02272478 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study NCT01754454 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT00968864 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT02233114 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT02106975 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02106975 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study NCT00400764 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT01338103 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT00651391 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT00651391 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00651391 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00651391 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03918148 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT03918148 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02187744 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02067130 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study NCT00855673 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00519467 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study NCT04603963 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT02938156 — Biomarker: SHB mRNA
Type: Predictive Biomarker (PRD)
Genes: SHB
Study NCT03766074 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03748784 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03625700 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03222453 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study NCT00902889 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study NCT00902889 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study NCT01083940 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03851523 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03851523 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00332761 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02393781 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study NCT02178826 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study NCT00999609 — Biomarker: RPE65 mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE65
Study NCT00999609 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study NCT02212925 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT00450255 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02298530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00981201 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study NCT03543176 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study NCT01358045 — Biomarker: SHH mRNA
Type: Predictive Biomarker (PRD)
Genes: SHH
Study NCT01358045 — Biomarker: Protein patched homolog 1
Type: Predictive Biomarker (PRD)
Genes: PTCH1; PTCH
Study NCT01358045 — Biomarker: SMO mRNA
Type: Predictive Biomarker (PRD)
Genes: SMO; SMOH
Study NCT01324479 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT00981370 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study NCT03846804 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study NCT02535507 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02211079 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT02211079 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6