AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 12958329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12958329 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10980588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8628544 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31177595 — Biomarker: TLL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLL1; TLL
Study 29301520 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23789873 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 2057467 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2057467 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22120044 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 19878615 — Biomarker: XPAC mRNA
Type: Predictive Biomarker (PRD)
Genes: XPA; XPAC
Study 19878615 — Biomarker: XPC mRNA
Type: Predictive Biomarker (PRD)
Genes: XPC; XPCC
Study 19878615 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 19878615 — Biomarker: ERCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC2; XPD; XPDC
Study 19878615 — Biomarker: ERCC5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC5; ERCM2; XPG; XPGC
Study 19878615 — Biomarker: ERCC6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC6
Study 19878615 — Biomarker: RAD23B mRNA
Type: Predictive Biomarker (PRD)
Genes: RAD23B
Study 15939621 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15939621 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15939621 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 2759694 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22303705 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 30055940 — Biomarker: F2RL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F2RL3; PAR4
Study 27930518 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 22343174 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10449889 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 377081 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 25286684 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29489494 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26864951 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 22891219 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 10752814 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 4031109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31808598 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 31808598 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 26580240 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 24007570 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 19082699 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9301350 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9301350 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 9301350 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 9301350 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25499944 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25499944 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20134177 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15722593 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8952583 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29785399 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12140146 — Biomarker: CD99 antigen
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD99; MIC2; MIC2X; MIC2Y
Study 20537501 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18544001 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15752161 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 9758088 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9758088 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30977081 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 31530577 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 24442886 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22435747 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2169703 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26318757 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17142825 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17091139 — Biomarker: MUC22 mRNA
Type: Predictive Biomarker (PRD)
Genes: MUC22; G4; PBMUCL1
Study 14751362 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 14751362 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 29762642 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 25264753 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 16757158 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 16757158 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 16757158 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 16757158 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 22718030 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22718030 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22718030 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 22718030 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6504709 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6504709 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 30043524 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30043524 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26807718 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 26807718 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24972936 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10395630 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10395630 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 1909085 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27623561 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 18210156 — Biomarker: IGFBP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP2; BP2; IBP2
Study 18210156 — Biomarker: IGFBP5 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP5; IBP5
Study 12727966 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12727966 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12727966 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 1317910 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27293194 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 26371397 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22980373 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22980373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27395349 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10333897 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8624083 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 8624083 — Biomarker: Amyloid beta peptide (1-40)
Type: Pharmacodynamic Biomarker (PDY)
Genes: APP; A4; AD1
Study 8624083 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 1760811 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1760811 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 1760811 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 24820046 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 18977274 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 8018020 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8313931 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30975178 — Biomarker: Urokinase plasminogen activator surface receptor
Type: Monitoring Biomarker (MOI)
Genes: PLAUR; MO3; UPAR
Study 19309251 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18690935 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3145972 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29956883 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 29956883 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 27135249 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 16613273 — Biomarker: ARHGEF12 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARHGEF12; KIAA0382; LARG
Study 9547934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21179101 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21179101 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 7924366 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23296826 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 19139845 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17005074 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17005074 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9988392 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 2121564 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 2121564 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 19369910 — Biomarker: DTNBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DTNBP1; BLOC1S8; My031
Study 16733865 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11227239 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 9355712 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8467614 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 8467614 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3896279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28082531 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28082531 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21317203 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21317203 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19061882 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12638399 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 3280483 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10385494 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30725315 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 21914313 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14514946 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 1829901 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1829901 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 17663100 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17663100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7609517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3539691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22850935 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19432693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17088127 — Biomarker: CAMP mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMP; CAP18; FALL39; HSD26
Study 17088127 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17088127 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26889617 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 21294143 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 19057883 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16371605 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 15327421 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26090394 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 22549432 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 22549432 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19464865 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 7200736 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20963411 — Biomarker: WT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WT1
Study 20963411 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 18426091 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9743309 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 23219236 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 23219236 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23219236 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12886826 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8439201 — Biomarker: HLA-A mRNA
Type: Predictive Biomarker (PRD)
Genes: HLA-A; HLAA
Study 31357402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22163454 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22163454 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10208142 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8903607 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 26418629 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 26402815 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 17132351 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18997913 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 23318995 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 15309879 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 15309879 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 8121962 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 20462055 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15557131 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29695902 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22344744 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 22344744 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 16765100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6991446 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 15475437 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 10442372 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 1914554 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17410097 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 17410097 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8018617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8018617 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16740758 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3818510 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16235461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22770372 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22770372 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15654172 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12208593 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25041227 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 22299599 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 15662209 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7096960 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 25712437 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12502654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7081117 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28982740 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28982740 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18696359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10220271 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10220271 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 26046796 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 26046796 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 24093487 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24093487 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 11157314 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 31617739 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24102851 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19925286 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 10356097 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 8832603 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 29171086 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 30764560 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 19769793 — Biomarker: UCP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP2; SLC25A8
Study 19769793 — Biomarker: UCP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP3; SLC25A9
Study 14972792 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 14972792 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30711649 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 29142982 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 29142982 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)