AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23591634 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9514186 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9514186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18052567 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18052567 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26761518 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26761518 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 9314118 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 2427807 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2427807 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28473924 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10924606 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 25727851 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 16968848 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9309626 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8312677 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8312677 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 8312677 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17345818 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1798594 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 1798594 — Biomarker: Complement C4
Type: Monitoring Biomarker (MOI)
Study 30545718 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30545718 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28988232 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28988232 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17237662 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 17237662 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 15566918 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8659195 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 8659195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22978099 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22978099 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 22978099 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 20089449 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 15604959 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 7571793 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26999197 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 27522059 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 27522059 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27522059 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 27522059 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 27522059 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 17215608 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11079660 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 11079660 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11079660 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9348547 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 30249630 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 18443573 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15977465 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15977465 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 14534616 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 31371391 — Biomarker: TRPV4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV4; VRL2; VROAC
Study 25600484 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30724760 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 27530911 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 24906295 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 23279557 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 15118290 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15943220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28486559 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20482957 — Biomarker: OSR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OSR1; ODD
Study 14501599 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 11103826 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23185750 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23185750 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8257527 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 18197912 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18197912 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 17313855 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11022077 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 19463299 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 10802396 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31407320 — Biomarker: SOCS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOCS1; SSI1; TIP3
Study 16531614 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9380281 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 2864051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21865791 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15199624 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9523211 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 7535842 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7535842 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 19558562 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 19558562 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 19558562 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 11176172 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11176172 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 30780126 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 20414671 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 17873673 — Biomarker: OGT mRNA
Type: Predictive Biomarker (PRD)
Genes: OGT
Study 17873673 — Biomarker: Argininosuccinate synthase
Type: Safety Biomarker (SAF)
Genes: ASS1; ASS
Study 9918893 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7538412 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23121249 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23121249 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 21697300 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17085985 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8378854 — Biomarker: CGN mRNA
Type: Predictive Biomarker (PRD)
Genes: CGN; KIAA1319
Study 3005377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18315957 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29581078 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 26150543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17573449 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17573449 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17573449 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12410058 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 2496619 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23852061 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18503607 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 23395119 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12850965 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28453701 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19833861 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 19833861 — Biomarker: REEP5 mRNA
Type: Predictive Biomarker (PRD)
Genes: REEP5; C5orf18; DP1; TB2
Study 15154607 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 10631624 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1373007 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2857210 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 28515369 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24634929 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12834936 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2764852 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31424713 — Biomarker: WWTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WWTR1; TAZ
Study 18199805 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 11125309 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29316213 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18806039 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 25191766 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 22027944 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22027944 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18520980 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 10027435 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 1828336 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8637110 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 1824653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24727871 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24727871 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 24727871 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 17612907 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18515458 — Biomarker: BAD mRNA
Type: Predictive Biomarker (PRD)
Genes: BAD; BBC6; BCL2L8
Study 16685043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3312614 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30142868 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 27723839 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 27723839 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24516190 — Biomarker: MCCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCCC2; MCCB
Study 11688904 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26493551 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 20338501 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 20338501 — Biomarker: Mitochondrial membrane potential
Type: Pharmacodynamic Biomarker (PDY)
Study 25458446 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 18346173 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18346173 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18346173 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12945222 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24509980 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 17392668 — Biomarker: CDS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDS1; CDS
Study 21262880 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8879340 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16670154 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 26884081 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 24588813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18262041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12845425 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9597562 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8165070 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3210111 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26580235 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 22872107 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31043691 — Biomarker: Chitinase-3-like protein 1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: CHI3L1
Study 31043691 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21357374 — Biomarker: SOD2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SOD2
Study 21357374 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19603365 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17498484 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17498484 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15136785 — Biomarker: SRD5A1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SRD5A1
Study 15136785 — Biomarker: SRD5A2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SRD5A2
Study 15136785 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 7997845 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25593016 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 25593016 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 25593016 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 31527299 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 25833969 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23235355 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 23235355 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19874586 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 18044102 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 9631143 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16364165 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 3680600 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 12592681 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 30289802 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20660677 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 20660677 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12581507 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 22982023 — Biomarker: ABCC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC1; MRP; MRP1
Study 22982023 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15990571 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11889577 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19901655 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 19901655 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15549369 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 15549369 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 24863486 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 15215483 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24388167 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 16085339 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 1899732 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1899732 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 25325116 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22627919 — Biomarker: CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR1; C3BR
Study 22627919 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 23923010 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23923010 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11391226 — Biomarker: RRAD mRNA
Type: Predictive Biomarker (PRD)
Genes: RRAD; RAD
Study 8104238 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30114973 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 28868876 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 28868876 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 10962113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3529352 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26215222 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 25400056 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 26775476 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21398582 — Biomarker: CD160 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD160; BY55
Study 21398582 — Biomarker: CD244 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD244; 2B4
Study 18314433 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15864239 — Biomarker: RANGAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RANGAP1; KIAA1835; SD
Study 12202662 — Biomarker: Dihydrothymine dehydrogenase
Type: Safety Biomarker (SAF)
Genes: DPYD
Study 10599909 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 30995972 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25795029 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25795029 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23173698 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 11711490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28746977 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 27388615 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27388615 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18254893 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP