AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 25893544 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16914379 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28526223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18971533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8267146 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3300834 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30279267 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23815535 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18647232 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18647232 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18647232 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 18647232 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 18647232 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17050867 — Biomarker: CBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CBX1; CBX
Study 8720537 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 1448711 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 26313291 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22189669 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 11720758 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 6150724 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29894608 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 29894608 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27560704 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 27560704 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 10673189 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 10673189 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 6662157 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9028977 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 1504638 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22944289 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17825690 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9922587 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 9922587 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 2156649 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21624304 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30704266 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 2301751 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 26284338 — Biomarker: TLE3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLE3; KIAA1547
Study 11578885 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30864188 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30864188 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30864188 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30864188 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15915407 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12777951 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10490862 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31116675 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 16585301 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 16585301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10859628 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10859628 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27535752 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26178502 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26178502 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26178502 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23795745 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27524882 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 15668500 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 25614446 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 17578365 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17578365 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 15477366 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 12010353 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7872324 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 7872324 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 7872324 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 7872324 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24498872 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19694743 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 19694743 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 19694743 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 17171950 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17171950 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24073583 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19004038 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15990257 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28459238 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28459238 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22822024 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 22822024 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1998761 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1998761 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6689152 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 29559724 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24381122 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24381122 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10210048 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28028369 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 19930883 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19930883 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19930883 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 15860850 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 8390514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27137175 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21203437 — Biomarker: TLR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR5; TIL3
Study 17083342 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15034215 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 26160208 — Biomarker: SLC6A14 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A14
Study 26160208 — Biomarker: HTR2C mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2C; HTR1C
Study 6750325 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 6750325 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 6750325 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9444927 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 23957658 — Biomarker: FGF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF4; HST; HSTF1; KS3
Study 2686393 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28623892 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 26115976 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 26115976 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26115976 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19727022 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19727022 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 11724457 — Biomarker: PCLAF mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 26865200 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21051293 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15740824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17484523 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28438539 — Biomarker: RARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RARS1; RARS
Study 23474153 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 17699214 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21834921 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 17413559 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 20027849 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20027849 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15363817 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 15363817 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 29124630 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 2505717 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2505717 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25223986 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12823779 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study 12823779 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 23819814 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 21430255 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21430255 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10747518 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 8747844 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 8747844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8747844 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2478368 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 30308014 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 4013861 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 27173467 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22876725 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19901104 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 11985485 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28076331 — Biomarker: EPCAM mRNA
Type: Predictive Biomarker (PRD)
Genes: EPCAM; GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1
Study 12095313 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 12095313 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7484890 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28028192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19682173 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 19682173 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 16321616 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16321616 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9797755 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9797755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9797755 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 9797755 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9797755 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29356445 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 19671655 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study 19671655 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16280694 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12160199 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12160199 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24842200 — Biomarker: CARD16 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARD16; COP; COP1
Study 24842200 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31053082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27919453 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9719328 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 7695416 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 14504877 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1514346 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30059487 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30059487 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 23948830 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20306017 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24630505 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23420550 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 23420550 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 12477508 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 12477508 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12477508 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 6103766 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 17164234 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 10208393 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 10208393 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 10208393 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10208393 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 7829619 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 7829619 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 31993781 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 21331055 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 21331055 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31660654 — Biomarker: PRKN mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKN; PARK2
Study 31660654 — Biomarker: Synuclein alpha
Type: Pharmacodynamic Biomarker (PDY)
Genes: SNCA; NACP; PARK1
Study 31660654 — Biomarker: Leucine-rich repeat kinase 2
Type: Pharmacodynamic Biomarker (PDY)
Genes: LRRK2; PARK8
Study 31660654 — Biomarker: KANSL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KANSL1; CENP-36; KIAA1267; MSL1V1; NSL1
Study 31660654 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 31660654 — Biomarker: HLA-DQB1
Type: Safety Biomarker (SAF)
Genes: IDDM1; CELIAC1
Study 25604313 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25604313 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 25604313 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 25604313 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 25604313 — Biomarker: CCR2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCR2; CMKBR2
Study 25604313 — Biomarker: TLR2
Type: Predictive Biomarker (PRD)
Genes: TIL4; CD282
Study 14676650 — Biomarker: HSPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPD1; HSP60
Study 11967819 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3429696 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27371106 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16123483 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 1610589 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16302004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7843440 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 1334803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6502311 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 28524039 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28524039 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15307012 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7506324 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 7506324 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7506324 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8912763 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27701370 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 26934294 — Biomarker: FANCE mRNA
Type: Predictive Biomarker (PRD)
Genes: FANCE; FACE
Study 24251724 — Biomarker: FMOD mRNA
Type: Predictive Biomarker (PRD)
Genes: FMOD; FM; SLRR2E
Study 23010601 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 18226292 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15298982 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15298982 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 15298982 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7753268 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20031767 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9562003 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 8148354 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25835443 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9396415 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1286654 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR