AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 6504920 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 6504920 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 17590217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12357730 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12357730 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26283175 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10871979 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10871979 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24904785 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20147743 — Biomarker: FGFR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR4; JTK2; TKF
Study 12461659 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8822109 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 30669360 — Biomarker: JUN mRNA
Type: Predictive Biomarker (PRD)
Genes: JUN
Study 30669360 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 21289621 — Biomarker: KCNQ1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNQ1; KCNA8; KCNA9; KVLQT1
Study 16849623 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 29198641 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 23578719 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12853193 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11173778 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6828338 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30115454 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 24463933 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19158191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17229249 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17229249 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28301428 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 24325112 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22136978 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15277147 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7862856 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25487613 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23594436 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 23594436 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23594436 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15086616 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 26297368 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21241489 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 21241489 — Biomarker: PPIC mRNA
Type: Predictive Biomarker (PRD)
Genes: PPIC; CYPC
Study 21241489 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12691509 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2866558 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 31070229 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 22693121 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 22693121 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 12085364 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9468078 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2505716 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31043657 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 21389149 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 17290043 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23091142 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 23091142 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19667110 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 19667110 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 10444645 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23433279 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 11696805 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 9137792 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7970538 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21136299 — Biomarker: OSR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OSR1; ODD
Study 9286888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24635387 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 24635387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20668035 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 9641612 — Biomarker: HHEX mRNA
Type: Predictive Biomarker (PRD)
Genes: HHEX; HEX; PRH; PRHX
Study 9641612 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 9641612 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 979068 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31070869 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31070869 — Biomarker: IL17F
Type: Predictive Biomarker (PRD)
Genes: IL-17F; ML-1; ML1
Study 24557584 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16364555 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15291656 — Biomarker: MARCKS mRNA
Type: Predictive Biomarker (PRD)
Genes: MARCKS; MACS; PRKCSL
Study 15291656 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 11115082 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 11115082 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11115082 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11115082 — Biomarker: Urinary total protein
Type: Safety Biomarker (SAF)
Study 1361311 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1361311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26023230 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16699858 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1482251 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 1482251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6094103 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 3884691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20501356 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31832001 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 31832001 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 31832001 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23936148 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 31778222 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3318454 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3318454 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30333494 — Biomarker: SPINK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPINK1; PSTI
Study 30333494 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20419161 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20419161 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17311303 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 17311303 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 11374852 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8795482 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 7745993 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 23644384 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23644384 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 23644384 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 11699405 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 8281674 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22718435 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 16540931 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3977547 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 30959858 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9032191 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 3111784 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 31856379 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31135272 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 11515715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31841279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28293063 — Biomarker: miR-200c
Type: Safety Biomarker (SAF)
Genes: MIR200C
Study 11371420 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 2967186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29682796 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 24477179 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12360164 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7482063 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30934166 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 29779795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22778174 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21740986 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 21740986 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 14506950 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31551368 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 25606700 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 22942727 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 31391011 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 17139244 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17139244 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31859211 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 24057294 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21765448 — Biomarker: KCNJ11 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNJ11
Study 19647670 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14612206 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14612206 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 25295834 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 15228505 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 29106814 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29106814 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 707334 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 30841823 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21119150 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 18805249 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17079573 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12941710 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8742095 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 1418054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27490922 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 27490922 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27490922 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7300705 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30343264 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28219190 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 25597563 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30672218 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 22676245 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 20100026 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20100026 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 2524387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31619483 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21646062 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 16434666 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 15117853 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 31486133 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 17158426 — Biomarker: ACSM3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACSM3; SAH
Study 9228508 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 26183139 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2744186 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 2744186 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 2744186 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 22574588 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17082463 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23485078 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17470689 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29375198 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30286483 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28753100 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 8110432 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19798460 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 19798460 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19798460 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16177941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30873676 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 30873676 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30873676 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26731191 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22431960 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2501817 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 2501817 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30973493 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 23936348 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23936348 — Biomarker: MAP2K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K1; MEK1; PRKMK1
Study 23936348 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 23936348 — Biomarker: MAP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2
Study 15471552 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11287371 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11287371 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 11287371 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9100581 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 3390394 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 28297813 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26395094 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 23393157 — Biomarker: NLGN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLGN2; KIAA1366
Study 23393157 — Biomarker: NLGN4X mRNA
Type: Predictive Biomarker (PRD)
Genes: NLGN4X; KIAA1260; NLGN4; UNQ365/PRO701
Study 23393157 — Biomarker: NRXN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRXN1
Study 23393157 — Biomarker: NRXN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRXN2
Study 23393157 — Biomarker: NRXN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRXN3; KIAA0743
Study 23393157 — Biomarker: ARHGEF9 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARHGEF9; ARHDH9; KIAA0424
Study 22014698 — Biomarker: SLMAP mRNA
Type: Predictive Biomarker (PRD)
Genes: SLMAP; KIAA1601; SLAP; UNQ1847/PRO3577
Study 16329138 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12793617 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 30170853 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 20395358 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 10624765 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2167951 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 27959607 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27959607 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 19279975 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 19279975 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 15890545 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 2209240 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 24004237 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19477397 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 2067506 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2067506 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6193349 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20813872 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 30664020 — Biomarker: Bacteroidetes phylum
Type: Safety Biomarker (SAF)
Study 27062800 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 8011000 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 376236 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 28824041 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 21343556 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9176034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1376842 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29743380 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 29743380 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25113414 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 25113414 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)