AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 17559628 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 25403334 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25403334 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 25403334 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 25403334 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21241369 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 10704621 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 8403580 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 18398095 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16872244 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14635608 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1731577 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 9656236 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12138261 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29615318 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19786670 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19786670 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 16338019 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 8434556 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22397815 — Biomarker: KLK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLK4; EMSP1; PRSS17; PSTS
Study 22397815 — Biomarker: CDKN1B mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN1B; KIP1; p27
Study 22397815 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 27605038 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27605038 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8148353 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23704675 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23704675 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 22527287 — Biomarker: RYR1
Type: Safety Biomarker (SAF)
Genes: RYR; PPP1R137
Study 22527287 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22527287 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22527287 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10385662 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 6441537 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14727947 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14727947 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10540365 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10540365 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21131631 — Biomarker: AIP mRNA
Type: Predictive Biomarker (PRD)
Genes: AIP; XAP2
Study 19583605 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 19583605 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28673363 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 28673363 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11472042 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8049831 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 25500202 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 23363981 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14510756 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8409106 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29898752 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28115966 — Biomarker: FBXO8 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBXO8; FBS; FBX8; DC10; UNQ1877/PRO4320
Study 28115966 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17935553 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17935553 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17935553 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15736119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12137603 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12137603 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2550045 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2550045 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31052322 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24636286 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9064671 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6145533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29957706 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25375154 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 11115439 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9175684 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 9175684 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29229342 — Biomarker: SLC25A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A3; PHC; OK/SW-cl.48
Study 1328817 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30081930 — Biomarker: SPARC mRNA
Type: Predictive Biomarker (PRD)
Genes: SPARC; ON
Study 17709169 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 15986592 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 10703890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30228368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21697538 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10720025 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3999921 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 30014331 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 12660531 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23238616 — Biomarker: ALDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH2; ALDM
Study 30269143 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24508204 — Biomarker: PPP1R13L mRNA
Type: Predictive Biomarker (PRD)
Genes: PPP1R13L; IASPP; NKIP1; PPP1R13BL; RAI
Study 19996069 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15987849 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 25491299 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 20595285 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20595285 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7641363 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2238185 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2238185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31215156 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 31215156 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 26277033 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26277033 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7916274 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20625342 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study 18025525 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 18025525 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 18025525 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 12166339 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18645322 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 21163558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19570039 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 12170362 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7749832 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 2301259 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31918243 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 21936966 — Biomarker: GPX3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPX3; GPXP
Study 21936966 — Biomarker: GPX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPX1
Study 11464715 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9972055 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 29148175 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 9012686 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 9012686 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 31692559 — Biomarker: CSPG4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CSPG4; MCSP
Study 29269513 — Biomarker: F2RL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F2RL3; PAR4
Study 19406976 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 17446813 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23078531 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23078531 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18555517 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17031403 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17031403 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 17031403 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 17031403 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 17031403 — Biomarker: CD6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD6
Study 17031403 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 17031403 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 17031403 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 17031403 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 7710841 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 3236318 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25526733 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 14535967 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10933361 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10933361 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8299252 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3883917 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29397160 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24270743 — Biomarker: Heart fatty acid-binding protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FABP3; FABP11; MDGI
Study 24270743 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 16351668 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16351668 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1940682 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22951349 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22951349 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22951349 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19317065 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17410461 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 9849273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8014393 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 25940759 — Biomarker: GSS mRNA
Type: Predictive Biomarker (PRD)
Genes: GSS
Study 11256874 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 11256874 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 19924010 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1826071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30938760 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 15333608 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 18678703 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 31779786 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18228523 — Biomarker: MITF mRNA
Type: Predictive Biomarker (PRD)
Genes: MITF; BHLHE32
Study 16472797 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16472797 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1835914 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1835914 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25330083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27918931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27918931 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 11213545 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 11213545 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3546779 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29484548 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29484548 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27390150 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27390150 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17941871 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 17941871 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17941871 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12813380 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 11263274 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 31783777 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 31783777 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31783777 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29187474 — Biomarker: GPX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPX1
Study 29187474 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27721534 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10913921 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30756411 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30756411 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26688003 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 18194413 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 15672001 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10822909 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 24562349 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24562349 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18611150 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30932134 — Biomarker: SLC7A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC7A5; CD98LC; LAT1; MPE16
Study 30932134 — Biomarker: CASTOR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CASTOR1; GATSL3
Study 30932134 — Biomarker: 40S ribosomal protein S6
Type: Predictive Biomarker (PRD)
Genes: RPS6; OK/SW-cl.2
Study 23413492 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26679879 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 14529880 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14529880 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11092645 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11092645 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27171844 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30880163 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29283224 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7621644 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7621644 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31361307 — Biomarker: IGFBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP1; IBP1
Study 31361307 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 23688096 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19901116 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19901116 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19901116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9459537 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27245786 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19921347 — Biomarker: CD74 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD74; DHLAG
Study 17092376 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 10100082 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10100082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31481039 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31481039 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28902880 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27175681 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 24585267 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16087825 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26576619 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 25553599 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25553599 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 14498755 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14498755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3898701 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30255760 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2