AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 8477190 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3797397 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20400408 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18722869 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14626182 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14626182 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14626182 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9190630 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25894123 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14683522 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8290458 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 3014110 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22233558 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 20444751 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 20444751 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15837944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10516539 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 10516539 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 30889042 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study 30889042 — Biomarker: Solute carrier family 29 member 1
Type: Predictive Biomarker (PRD)
Genes: SLC29A1; ENT1
Study 30889042 — Biomarker: SLC28A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC28A1; CNT1
Study 30889042 — Biomarker: Equilibrative nucleoside transporter 2
Type: Predictive Biomarker (PRD)
Genes: SLC29A2; DER12; ENT2; HNP36
Study 30889042 — Biomarker: TGFB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TGFB2
Study 24915778 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 7538556 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17890965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25524863 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22172255 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19586556 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9568678 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 8043996 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 8043996 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12660585 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3513516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11941903 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11941903 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10024093 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19542895 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22751169 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18703937 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 1325880 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26768146 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 20405117 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 7783097 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26792619 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10638393 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 27443226 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 27443226 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study 24026563 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 9708514 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 23510018 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23510018 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15272397 — Biomarker: Carbonic anhydrase IX
Type: Predictive Biomarker (PRD)
Genes: CA9; G250; MN
Study 31620896 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 30839090 — Biomarker: PLG mRNA
Type: Predictive Biomarker (PRD)
Genes: PLG
Study 27698102 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21346110 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 16391591 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12175635 — Biomarker: C4A mRNA
Type: Predictive Biomarker (PRD)
Genes: C4A; CO4; CPAMD2
Study 7005293 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29926675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29926675 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29926675 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10520573 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 15145964 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 15145964 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 1646621 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1646621 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24718367 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 24718367 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 20598667 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 16368446 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16368446 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2574051 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 31061252 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31061252 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 31061252 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26314532 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 11138573 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9177418 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3429867 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17003850 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 17003850 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 18551027 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18551027 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27780772 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 8735678 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30286130 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 24725198 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24725198 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22345126 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 22345126 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22345126 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22345126 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15625424 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 12045365 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12045365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23859894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15028366 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12796139 — Biomarker: ELK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELK3; NET; SAP2
Study 12796139 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12796139 — Biomarker: NE
Type: Predictive Biomarker (PRD)
Study 12796139 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6383779 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29853984 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 17212718 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 2210795 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 31397126 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31397126 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 12629445 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11003427 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11003427 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 3002786 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20345732 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 11684917 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25928356 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25928356 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 22699800 — Biomarker: HGD mRNA
Type: Predictive Biomarker (PRD)
Genes: HGD; HGO
Study 16708528 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 16708528 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8285455 — Biomarker: CDS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDS1; CDS
Study 21611944 — Biomarker: CRCP mRNA
Type: Predictive Biomarker (PRD)
Genes: CRCP
Study 21611944 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 27842499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24447332 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 24447332 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 10720584 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26743775 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16970088 — Biomarker: CR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR2; C3DR
Study 10474785 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22976847 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27017403 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 17519792 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 6460207 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6460207 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 29192240 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 25764160 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25764160 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25764160 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 23846820 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20618506 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 18251761 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 19117319 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 11247319 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11247319 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8502260 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 3551212 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20103775 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20103775 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14586384 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 14586384 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 14586384 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 14586384 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 3011440 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3011440 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1095262 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1095262 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 1095262 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28835090 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 28835090 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 23929930 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18923232 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18923232 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 12456382 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 22965961 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22965961 — Biomarker: VEGF
Type: Predictive Biomarker (PRD)
Genes: VEGFA; VEGF-A; VPF
Study 22965961 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19944872 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15044672 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15044672 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9787721 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23993326 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9350563 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 1778859 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7340890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29288184 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25819697 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21124000 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 8940729 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 8940729 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 3907967 — Biomarker: ELK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELK3; NET; SAP2
Study 27573605 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 3547214 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 19280185 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 19280185 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 1105489 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23757615 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 17259554 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15235928 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8513310 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23311173 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20624316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8573730 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31564377 — Biomarker: FADS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS1; FADSD5
Study 31564377 — Biomarker: FADS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS2
Study 31564377 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23816023 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 21801326 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15193684 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15193684 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27085660 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 24581465 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2773895 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25140000 — Biomarker: EGFL7 mRNA
Type: Predictive Biomarker (PRD)
Genes: EGFL7; MEGF7; UNQ187/PRO1449
Study 25140000 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 19148838 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 30586746 — Biomarker: ABCD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCD1; ALD
Study 15449150 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 9684137 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 1969567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23648352 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 15491247 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18353632 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16850908 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 12620695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9196432 — Biomarker: PSMB6 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSMB6; LMPY; Y
Study 26685099 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20956707 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17460371 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 29623516 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 27194097 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25001365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15707996 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27181260 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 25043685 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15973546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14507948 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31278755 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 31278755 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 24977755 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31598823 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31598823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23417031 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 21036583 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18080399 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18080399 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 18080399 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 15535413 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2841053 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2841053 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 22936619 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 19759166 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7923966 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27918762 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27918762 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25753207 — Biomarker: SNRPB mRNA
Type: Predictive Biomarker (PRD)
Genes: SNRPB; COD; SNRPB1
Study 9051855 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22244035 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29386413 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29386413 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29386413 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10516692 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10516692 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7516191 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7516191 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34