AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 19453695 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18719788 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11078311 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 11078311 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11078311 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30420421 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30420421 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27593617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25014057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8137520 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2573377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28693427 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17143189 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15334195 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 2506754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11477855 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 11477855 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 2672065 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31111697 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 22025856 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17291931 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9152683 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27260515 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 22208477 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 22208477 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 22208477 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 8527074 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27417177 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26637849 — Biomarker: PAX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAX2
Study 26637849 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 16601570 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 453892 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 28376855 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 28376855 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 28376855 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 16403097 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16403097 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 16403097 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 23635051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19521435 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 16183426 — Biomarker: TSC2
Type: Predictive Biomarker (PRD)
Genes: tuberin; LAM; PPP1R160
Study 30768550 — Biomarker: AQP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP1; CHIP28
Study 27333960 — Biomarker: Vascular endothelial cadherin
Type: Safety Biomarker (SAF)
Genes: CDH5
Study 2660333 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 31138063 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 21600843 — Biomarker: LGI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LGI1; EPT; UNQ775/PRO1569
Study 27749578 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 24886681 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 24886681 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24886681 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 10447055 — Biomarker: SLC4A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC4A4; NBC; NBC1; NBCE1
Study 19183470 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 8687090 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17157900 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 508019 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 508019 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28538371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19994687 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 7894213 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31927533 — Biomarker: PEX11A mRNA
Type: Predictive Biomarker (PRD)
Genes: PEX11A; PEX11
Study 31927533 — Biomarker: NLRP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP2; NALP2; NBS1; PAN1; PYPAF2
Study 31927533 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 31927533 — Biomarker: CTTN mRNA
Type: Predictive Biomarker (PRD)
Genes: CTTN; EMS1
Study 31927533 — Biomarker: D2HGDH mRNA
Type: Predictive Biomarker (PRD)
Genes: D2HGDH; D2HGD
Study 26677212 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23728101 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21126528 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 9535210 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 23642377 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23642377 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15579791 — Biomarker: ABCC8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC8; HRINS; SUR; SUR1
Study 15579791 — Biomarker: KCNJ11 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNJ11
Study 11254753 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9430375 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17962712 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9445199 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8037567 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 28263039 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24708857 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 21983797 — Biomarker: IGFBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP1; IBP1
Study 21983797 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 16123753 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 16123753 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 10368446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25322754 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 15691618 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 15691618 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27932570 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 27932570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24204594 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24204594 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10902748 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8883124 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8883124 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 1423336 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24614628 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24614628 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24614628 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15486802 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15486802 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3731679 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29778773 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27338467 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21543653 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 21543653 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 10503166 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23984312 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23984312 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 19424038 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 29335791 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21436923 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17126650 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9499812 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 1838916 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28213566 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 28213566 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21880799 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21880799 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18854202 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 24874285 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 22230143 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21602259 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study 21602259 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17462550 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11562580 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 2683545 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 30103216 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 26283139 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15561322 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11731185 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 20533221 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31517677 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11899648 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 11899648 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30854818 — Biomarker: DNA repair endonuclease XPF
Type: Predictive Biomarker (PRD)
Genes: ERCC4; ERCC11; XPF
Study 18725429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12887479 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30666969 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23391635 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12794182 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12794182 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25349059 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19137426 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15832952 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 15832952 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24552317 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9475531 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2225560 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2225560 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24114461 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 24114461 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19426239 — Biomarker: OGT mRNA
Type: Predictive Biomarker (PRD)
Genes: OGT
Study 352706 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11834534 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25922846 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study 25922846 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25922846 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24666922 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 15247958 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 10805824 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 10805824 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2875927 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 24896807 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10221346 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10221346 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7590642 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 7590642 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2126985 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 26911112 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17294437 — Biomarker: ACAD8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAD8; ARC42; IBD
Study 9236425 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9236425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15658647 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15658647 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15658647 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 31926484 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27125141 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 18464887 — Biomarker: LRIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LRIT1; LRRC21; PAL
Study 2179282 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2179282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27517842 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 16603964 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 29360622 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 29360622 — Biomarker: CEBPA mRNA
Type: Predictive Biomarker (PRD)
Genes: CEBPA; CEBP
Study 10517211 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7670449 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 2175354 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7030750 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17414675 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16343099 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8949573 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 8949573 — Biomarker: SERPINA7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA7; TBG
Study 8949573 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 24954556 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7828347 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 26285023 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 24472321 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 10091762 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7584517 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 7584517 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 7584517 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 21550218 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15226463 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29321031 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29321031 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26978860 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17275225 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24377211 — Biomarker: STC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STC1; STC
Study 16144819 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 11007567 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7877825 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29038157 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29038157 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 14669165 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31805989 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24041301 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 30685440 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16945213 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10749783 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8703455 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 8703455 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1305043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3977491 — Biomarker: CLYBL mRNA
Type: Predictive Biomarker (PRD)
Genes: CLYBL; CLB
Study 29884682 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23197572 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 16395320 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9104618 — Biomarker: CD79A mRNA
Type: Predictive Biomarker (PRD)
Genes: CD79A; IGA; MB1
Study 8478668 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12198052 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16435471 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 25294016 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25294016 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21255957 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19593886 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15296886 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 9285433 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29853453 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20619475 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 8852414 — Biomarker: SECTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SECTM1; K12
Study 31575423 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10581593 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8074597 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28583396 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23413998 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 23413998 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 8123500 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH