AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 21075373 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17554242 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2181858 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 463054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31919583 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30594190 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 16643492 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14657545 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 10816186 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 1452381 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27438995 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20713879 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20713879 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 20713879 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 8568294 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 16202258 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16202258 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29558967 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 23159258 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22257480 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 19152958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11879862 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11879862 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11879862 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10439732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2240380 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 323297 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22178855 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 30888478 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30888478 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30888478 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 27591157 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 18089329 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 18089329 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16258087 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 24473436 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 24473436 — Biomarker: SOCS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOCS3; CIS3; SSI3
Study 24473436 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17397005 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 6777458 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19065670 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9854458 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28682922 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24298779 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 8951977 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8951977 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 6755527 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27155740 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10503054 — Biomarker: FMN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMN1; FMN; LD
Study 10503054 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 7477143 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26683986 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 26683986 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23404211 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23404211 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23404211 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 20047626 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15629218 — Biomarker: RHD mRNA
Type: Predictive Biomarker (PRD)
Genes: RHD
Study 1574973 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31308004 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 29031409 — Biomarker: DSP mRNA
Type: Predictive Biomarker (PRD)
Genes: DSP
Study 18175148 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18175148 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 18175148 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 18175148 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16918262 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16918262 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 16918262 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30150756 — Biomarker: ADGRL4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADGRL4; ELTD1; ETL; UNQ202/PRO228
Study 24750839 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24750839 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 24750839 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30592948 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26686755 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 26686755 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 12195192 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12195192 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31067546 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 16840383 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 12617264 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11783309 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11783309 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27927602 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27131642 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 27131642 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22394170 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 19236730 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 19236730 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 16266300 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23507858 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 21838823 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21838823 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 21838823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2182891 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 2182891 — Biomarker: CD9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD9; MIC3; TSPAN29; GIG2
Study 2182891 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 7010382 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27236654 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31338563 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9398701 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 9398701 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 28642308 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23551727 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23551727 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23551727 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27518195 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 23406757 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23406757 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23406757 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23406757 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 15755765 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26908741 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 28394521 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 26835147 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10215943 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 7529482 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 1706665 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 1706665 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 16776048 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28830083 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28830083 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23848141 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 18279739 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 18279739 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17157119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12925319 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21873668 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 11417951 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7544967 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 21636711 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9162622 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9162622 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 31800931 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28418398 — Biomarker: OXTR mRNA
Type: Predictive Biomarker (PRD)
Genes: OXTR
Study 17349080 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17349080 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9396883 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7911290 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9715761 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7873290 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23481448 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 10833065 — Biomarker: AOX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AOX1; AO
Study 10833065 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 22882579 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 25318924 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17943541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11717654 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30357360 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 27678430 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 27678430 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 27678430 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23437399 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8314291 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31501920 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28832288 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23165913 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19901110 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 19901110 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 16546486 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16546486 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16546486 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 17384344 — Biomarker: ADIPOQ mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 2030596 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29074595 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 29074595 — Biomarker: CALR mRNA
Type: Predictive Biomarker (PRD)
Genes: CALR; CRTC
Study 26365936 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 17301218 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 17301218 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17301218 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 8115156 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 25867399 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25867399 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17299078 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7870278 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7870278 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 7870278 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 31012599 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 11089744 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 8462386 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8462386 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2939220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29648488 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 27458223 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 15198156 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 24399647 — Biomarker: Ataxin-3
Type: Pharmacodynamic Biomarker (PDY)
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 25204553 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8630380 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30232083 — Biomarker: STIL mRNA
Type: Predictive Biomarker (PRD)
Genes: STIL; SIL
Study 30232083 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 30232083 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 30232083 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 2170820 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2170820 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25530275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24197662 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20722559 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15793048 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7721614 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 2047898 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16438453 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 27491377 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17827461 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 26897518 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 28169875 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28169875 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28169875 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9817266 — Biomarker: CA10 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA10; hucep-15; UNQ533/PRO1076
Study 3582314 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3294618 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19900070 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 15451915 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16810076 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11465619 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2196144 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2196144 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18565951 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 8522064 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2859782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30051198 — Biomarker: SSTR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SSTR5
Study 18582370 — Biomarker: PGP mRNA
Type: Predictive Biomarker (PRD)
Genes: PGP
Study 1346558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6383990 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 10389558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1900007 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30255418 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 24881993 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18398278 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8638792 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29072815 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27989874 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11505809 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 11505809 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 2792164 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 31802120 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 28333997 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 10999263 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 22353811 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22353811 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22353811 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22353811 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8