AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 1610161 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 31103608 — Biomarker: PAPPA mRNA
Type: Predictive Biomarker (PRD)
Genes: PAPPA
Study 31103608 — Biomarker: PAPPA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAPPA2; PLAC3
Study 3131794 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 15315998 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 15315998 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30810638 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24279801 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 12808175 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10492157 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 8697718 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20039889 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 16258155 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30201024 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25453515 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29068977 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 19486654 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9829706 — Biomarker: SLC25A21 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A21; ODC
Study 27670267 — Biomarker: SLC12A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC12A3; NCC; TSC
Study 23701492 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 19056550 — Biomarker: FBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBP1; FBP
Study 15383083 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31144547 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 29337906 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22607134 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16219883 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28138133 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 25968249 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 11465636 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11465636 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 30902613 — Biomarker: EML4 mRNA
Type: Predictive Biomarker (PRD)
Genes: EML4; C2orf2; EMAPL4
Study 30902613 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 22000927 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 15486846 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8873668 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 24890531 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18551008 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31714586 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 31714586 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 31714586 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 31270967 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 22297674 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 22297674 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9927810 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 25560821 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17109365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2939216 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24442226 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17519080 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 26123096 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 26123096 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 19927141 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 10846637 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8198040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29704228 — Biomarker: GATA-type zinc finger protein 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ZGLP1; GLP1
Study 29704228 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 29704228 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 18454096 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 16816661 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28038680 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 24998644 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24998644 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19256282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15955629 — Biomarker: Leucine-rich repeat kinase 2
Type: Pharmacodynamic Biomarker (PDY)
Genes: LRRK2; PARK8
Study 12702130 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10233027 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 19542207 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 19542207 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2768706 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2768706 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2768706 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19138610 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 27096358 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23895132 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23895132 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 23895132 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 23895132 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 6256423 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31311386 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29879249 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 7988250 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 7988250 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16792584 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 10479132 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10479132 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10479132 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 10479132 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1937663 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6289857 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6289857 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24372004 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 28331003 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 28331003 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 10980901 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20719727 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18812884 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15909491 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 11783197 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8609343 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8609343 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18725484 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8859726 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 8859726 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8859726 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 8859726 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8859726 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30605922 — Biomarker: TXN mRNA
Type: Predictive Biomarker (PRD)
Genes: TXN; TRDX; TRX; TRX1
Study 16209965 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 1409873 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30031679 — Biomarker: SPX mRNA
Type: Predictive Biomarker (PRD)
Genes: SPX; C12orf39
Study 26873871 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26873871 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24571754 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 18519845 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18519845 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1971472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11136260 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1449922 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23044303 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24971340 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 20176498 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 10211628 — Biomarker: ALAD mRNA
Type: Predictive Biomarker (PRD)
Genes: ALAD
Study 7744517 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 28931220 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 28931220 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 23380105 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 20880552 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 27245056 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24311515 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 22203134 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 10491451 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 8367920 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 8367920 — Biomarker: REG3A mRNA
Type: Predictive Biomarker (PRD)
Genes: REG3A; HIP; PAP; PAP1
Study 31578169 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10934908 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 8071050 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3338250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10928293 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 3710012 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3710012 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 27916047 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27916047 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 12009244 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 31081862 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25305506 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 25305506 — Biomarker: MLH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MLH1; COCA2
Study 25305506 — Biomarker: DNA mismatch repair protein MSH2
Type: Predictive Biomarker (PRD)
Genes: MSH2
Study 21865946 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 21865946 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 21865946 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 19262477 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16752259 — Biomarker: SLC11A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC11A1; LSH; NRAMP; NRAMP1
Study 30796122 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 30796122 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 27640067 — Biomarker: CXCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR1; CMKAR1; IL8RA
Study 27640067 — Biomarker: CXCR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR2; IL8RB
Study 20102922 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20102922 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23126345 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12616983 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12616983 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 12616983 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 6127888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26395743 — Biomarker: GLUL mRNA
Type: Predictive Biomarker (PRD)
Genes: GLUL; GLNS
Study 24944131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17192324 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15051570 — Biomarker: COL17A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL17A1; BP180; BPAG2
Study 31466276 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 24029542 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 24029542 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 24029542 — Biomarker: CYP4F2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP4F2
Study 9562691 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 2894548 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18315784 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 18315784 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 18315784 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 17023870 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 17023870 — Biomarker: SNAP25 mRNA
Type: Predictive Biomarker (PRD)
Genes: SNAP25; SNAP
Study 26443696 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 29617381 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 25208561 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 25208561 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31779479 — Biomarker: TMPRSS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMPRSS2; PRSS10
Study 30566590 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23795737 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20153154 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 15554359 — Biomarker: TSHR mRNA
Type: Predictive Biomarker (PRD)
Genes: TSHR; LGR3
Study 11499801 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 27506909 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26464000 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12483466 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7570730 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11309322 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22057076 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9920455 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 27565240 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 27565240 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12079930 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 9617439 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 2721119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20938210 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 3827416 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9378830 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study 3017391 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24884578 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20298851 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 665656 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31473412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7529528 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 3278431 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12559678 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9352695 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 8462384 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8462384 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3081923 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30027590 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17669242 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 29791829 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 29791829 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 27161018 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24624911 — Biomarker: ABCC4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC4; MOATB; MRP4
Study 24624911 — Biomarker: ABCC5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC5; MRP5
Study 24624911 — Biomarker: IMPDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IMPDH1; IMPD1
Study 24624911 — Biomarker: ITPA mRNA
Type: Predictive Biomarker (PRD)
Genes: ITPA; C20orf37; My049; OK/SW-cl.9
Study 24624911 — Biomarker: CNT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC28A3; CNT3
Study 24624911 — Biomarker: XDH mRNA
Type: Predictive Biomarker (PRD)
Genes: XDH; XDHA
Study 24624911 — Biomarker: ATP6AP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATP6AP2; ATP6IP2; CAPER; ELDF10; HT028; MSTP009; PSEC0072
Study 24624911 — Biomarker: FRMD4B mRNA
Type: Predictive Biomarker (PRD)
Genes: FRMD4B; GRSP1; KIAA1013
Study 24624911 — Biomarker: GNG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNG2
Study 24624911 — Biomarker: KCNMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNMA1; KCNMA; SLO
Study 24624911 — Biomarker: NME1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NME1; NDPKA; NM23
Study 23394510 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 23394510 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18757663 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 23857436 — Biomarker: DIAPH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DIAPH2; DIA
Study 7981446 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31426673 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22964434 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 15076648 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15076648 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 11425688 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25517389 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25517389 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3687684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19014834 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19014834 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)