AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 15640476 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12195349 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28667705 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 26444692 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21203877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23746205 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23746205 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23746205 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23746205 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20305399 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 20305399 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 20305399 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 20305399 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 20305399 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16737761 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15381513 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 20145446 — Biomarker: ACAD8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAD8; ARC42; IBD
Study 26072396 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 19550356 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28290800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24131075 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 19717481 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15839181 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8893636 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29229898 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22971904 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22971904 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9625220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24218528 — Biomarker: LARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LARS1; KIAA1352; LARS
Study 20538557 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20538557 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16291416 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 30829203 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25864739 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 25864739 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 25864739 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 25864739 — Biomarker: IGFBP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP2; BP2; IBP2
Study 25864739 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 25864739 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 24007461 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24007461 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21411210 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9344323 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31295854 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31295854 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31295854 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23407306 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23407306 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21124330 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17996133 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25524834 — Biomarker: BOC mRNA
Type: Predictive Biomarker (PRD)
Genes: BOC; UNQ604/PRO1190
Study 23233710 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 8955546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22002685 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 12689357 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22607512 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 16205597 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16205597 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 16205597 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 8901799 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6848468 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29480175 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19821068 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 23529392 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 29348380 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31436835 — Biomarker: LAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LAT
Study 11434170 — Biomarker: TNFRSF25 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF25; APO3; DDR3; DR3; TNFRSF12; WSL; WSL1; UNQ455/PRO779
Study 11434170 — Biomarker: TOR1B mRNA
Type: Predictive Biomarker (PRD)
Genes: TOR1B; DQ1; FKSG18
Study 11434170 — Biomarker: TNFRSF10A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 841307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31141505 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 29937865 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23690688 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9002942 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28410612 — Biomarker: PALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PALM; KIAA0270
Study 10496529 — Biomarker: BAX mRNA
Type: Predictive Biomarker (PRD)
Genes: BAX; BCL2L4
Study 10496529 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 19514089 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 15168718 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25050869 — Biomarker: SERPINF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINF1; PEDF; PIG35
Study 25050869 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25050869 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 21931737 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21931737 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 18348715 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 4089582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22683613 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 22683613 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8334064 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3769183 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 29775957 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 20147846 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 30888975 — Biomarker: SLC25A20 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A20; CAC; CACT
Study 30888975 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29554282 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 22028294 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 22028294 — Biomarker: Ribonucleoside-diphosphate reductase large subunit
Type: Predictive Biomarker (PRD)
Genes: RRM1; RR1
Study 15610252 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21353673 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 31975053 — Biomarker: TERF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TERF1; PIN2; TRBF1; TRF; TRF1
Study 31740545 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 31740545 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 25247908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16075824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9935200 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 9935200 — Biomarker: MDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM2
Study 9935200 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 8520164 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 8520164 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 2106545 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 31753198 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 22194217 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 9445307 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9445307 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 9445307 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 628361 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 628361 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 18445058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10217000 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 10217000 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 10217000 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1941668 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 25622538 — Biomarker: Lysosomal alpha-glucosidase
Type: Safety Biomarker (SAF)
Genes: GAA
Study 24171842 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18838053 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10942632 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10942632 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10942632 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 27536869 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 23200175 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 23200175 — Biomarker: MAP2K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K1; MEK1; PRKMK1
Study 23200175 — Biomarker: MAP2K2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K2; MEK2; MKK2; PRKMK2
Study 21391924 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 19364873 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 9771299 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3071596 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30827971 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18778179 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18778179 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21809720 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16138713 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27886078 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22314083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12803583 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 30027612 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 9524897 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 30481999 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 30481999 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30481999 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28029445 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28029445 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9032192 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9032192 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 9032192 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 9032192 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 9032192 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 26758700 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15469666 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3780692 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30045422 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30045422 — Biomarker: PNO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PNO1
Study 25701171 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23069274 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 30282861 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 30282861 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22388325 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10073791 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30107043 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19874636 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31481683 — Biomarker: CD200R1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD200R1; CD200R; CRTR2; MOX2R; OX2R; UNQ2522/PRO6015
Study 31481683 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 26820158 — Biomarker: Vascular endothelial cadherin
Type: Safety Biomarker (SAF)
Genes: CDH5
Study 12413985 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8101011 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16075363 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10189133 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 8944997 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 28431533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21494767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11439795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 363434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28809610 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 23441835 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21221689 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 17719468 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17719468 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 10934984 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1286547 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 27609406 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 9524049 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19557003 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19557003 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15292745 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study 15292745 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30246694 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22169080 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 17643572 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30354231 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 22915615 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22915615 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19126893 — Biomarker: LHB mRNA
Type: Predictive Biomarker (PRD)
Genes: LHB
Study 19126893 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 12825127 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24419137 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 10971683 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 10971683 — Biomarker: BSN mRNA
Type: Predictive Biomarker (PRD)
Genes: BSN; KIAA0434; ZNF231
Study 6439566 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 6439566 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 28137402 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19962185 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 16825847 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8675168 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 6152275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19378423 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 10229744 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8722437 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21111770 — Biomarker: LIF mRNA
Type: Predictive Biomarker (PRD)
Genes: LIF; HILDA
Study 15189389 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2563388 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26357467 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 29127510 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21312072 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 21312072 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 20383871 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 2171792 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 21870979 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20584997 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6127896 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31092165 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28727908 — Biomarker: FFAR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FFAR1; GPR40
Study 23566419 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 23566419 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 19549430 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 19549430 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 19549430 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10748306 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 8729585 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8729585 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24253810 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22120090 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 22120090 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 22120090 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 9333181 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 7631088 — Biomarker: MGP mRNA
Type: Predictive Biomarker (PRD)
Genes: MGP; MGLAP; GIG36
Study 18279058 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF