AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 9085171 — Biomarker: UST mRNA
Type: Predictive Biomarker (PRD)
Genes: UST; DS2ST
Study 23802927 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15517934 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 15517934 — Biomarker: HCV DNA
Type: Monitoring Biomarker (MOI)
Study 15517934 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11182036 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 11182036 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7942935 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23744847 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 18199693 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 29210916 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29210916 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 29210916 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 29210916 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29210916 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 20056436 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 26765472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9574879 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 20434864 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10702430 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 29303067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29303067 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 16376417 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 18543484 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14584069 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 1740678 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27254652 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 27254652 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 15802109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31648564 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 2711711 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28501522 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24621800 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 14500934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1104047 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20367671 — Biomarker: AQP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP3
Study 20367671 — Biomarker: INVS mRNA
Type: Predictive Biomarker (PRD)
Genes: INVS; INV; NPHP2
Study 20367671 — Biomarker: FGFR1
Type: Predictive Biomarker (PRD)
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 18068618 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 9951478 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 108715 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 28599665 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 14699491 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11973248 — Biomarker: GCA mRNA
Type: Predictive Biomarker (PRD)
Genes: GCA; GCL
Study 3297575 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3297575 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22931254 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30461007 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18240190 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 14564679 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19880504 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 2658536 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 29097660 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 21959871 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19843557 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9990383 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 9990383 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 7532878 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 7532878 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9630111 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3350031 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23955482 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 15983303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21434335 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21434335 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 10969345 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3922903 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18589718 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15895289 — Biomarker: NPL mRNA
Type: Predictive Biomarker (PRD)
Genes: NPL; C1orf13
Study 2174321 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24447269 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12840180 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 12840180 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11789185 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30049462 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 30049462 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 27366013 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 12486865 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 29439358 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 26022961 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 6812301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31290981 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27435493 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 27435493 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 27435493 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15446406 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 11432891 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 30981696 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 3203713 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 16117882 — Biomarker: PSMB7 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSMB7; Z
Study 10734431 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 11224758 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21903983 — Biomarker: PRKD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKD1; PKD; PKD1; PRKCM
Study 21903983 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 21903983 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21903983 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19012954 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 10522991 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8547869 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 8547869 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19005406 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 14617313 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 9368200 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 3304515 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 27009868 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7857357 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 30828846 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 28991599 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25785968 — Biomarker: SMAD7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMAD7; MADH7; MADH8
Study 9833852 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9833852 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 2476608 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2476608 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2476608 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15265851 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3818718 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1575174 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26390226 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 23897964 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 21046236 — Biomarker: ABCC6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC6; ARA; MRP6
Study 14669936 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2371491 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28176907 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24989711 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 24989711 — Biomarker: Vascular endothelial cadherin
Type: Safety Biomarker (SAF)
Genes: CDH5
Study 24989711 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 24989711 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 19486346 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 19486346 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11151420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22976741 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15201136 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29208686 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 25524023 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25524023 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 24693681 — Biomarker: AOX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AOX1; AO
Study 24693681 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 20801521 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 15474755 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 15474755 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28826262 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15725138 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10443663 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30892810 — Biomarker: PPP1CB mRNA
Type: Predictive Biomarker (PRD)
Genes: PPP1CB
Study 30892810 — Biomarker: HOXA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HOXA1; HOX1F
Study 30892810 — Biomarker: miR-125b
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27329344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19301038 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17525363 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17525363 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 12888182 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 8673999 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7044709 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11965204 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11965204 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 25782428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11477498 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8176150 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 30084517 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study 17201236 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 2685984 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11369837 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 7837323 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26637673 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19799020 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17804774 — Biomarker: RITA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RITA1; C12orf52; RITA; PSEC0043
Study 18042505 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2041279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7226712 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 21393391 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 21393391 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 16814669 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 27082062 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 27082062 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 27082062 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 27082062 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27082062 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study 22612071 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18044544 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 21883997 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15957722 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9523811 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21865358 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21865358 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15342804 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 9377992 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3732422 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21322822 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 12784165 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12784165 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8681491 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21376050 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 17032921 — Biomarker: CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR1; C3BR
Study 15326083 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7613555 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 6282482 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21142856 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 8112373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24973875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26079469 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9649259 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 6848894 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23201472 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23201472 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 3124940 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 20581879 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 8941092 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 74660 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19200175 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 9037327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26180052 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 2060176 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31752105 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28893753 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 12218949 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 31495898 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study 28526014 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28526014 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8652960 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 2221287 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 30193574 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30193574 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10786744 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10786744 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9483214 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 9483214 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 9483214 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 9483214 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 24676848 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22172728 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22172728 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 7583899 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2182976 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2182976 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 17188618 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 11463766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26234407 — Biomarker: ISG15 mRNA
Type: Predictive Biomarker (PRD)
Genes: ISG15; G1P2; UCRP
Study 21248785 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28872484 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 26599904 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 15671570 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 7753338 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 20056802 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18566455 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 11840226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10512130 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 25481936 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25481936 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17559733 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 9766535 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7548903 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2247767 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2247767 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 2247767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7004473 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26842122 — Biomarker: CENPJ mRNA
Type: Predictive Biomarker (PRD)
Genes: CENPJ; CPAP; LAP; LIP1