AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31176888 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 25042693 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 28304146 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24130358 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9041330 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30110007 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27717299 — Biomarker: Homologous recombination deficiency
Type: Predictive Biomarker (PRD)
Study 18835931 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 18835931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15043569 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15043569 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 8142225 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 3144513 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 3144513 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 27197868 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25545856 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 18089770 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 16513919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16513919 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11002872 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 11002872 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9186076 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22482335 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 17270528 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3980055 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22048173 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10915072 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10915072 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 18634152 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 14637388 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 1370236 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 30565017 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28655596 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28655596 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7794572 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18270817 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 18270817 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 11817496 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 7554698 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 2202384 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2202384 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22828124 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 20980999 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20980999 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8635265 — Biomarker: EDNRA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDNRA; ETA; ETRA
Study 8635265 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 26460907 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 1837202 — Biomarker: Lysosomal alpha-glucosidase
Type: Safety Biomarker (SAF)
Genes: GAA
Study 30449623 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 26861603 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 21922153 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 17439900 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 17439900 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 28864675 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21132308 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19438487 — Biomarker: MEA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MEA1; MEA
Study 15465501 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11394516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7672871 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 31477497 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 26202150 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 16954164 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8316388 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 26554670 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 16921788 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11120762 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 9212967 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 8427165 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 29754930 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26410046 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 14728824 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 1875406 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3485932 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29413495 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 29413495 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 29413495 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 18423747 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11010055 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11010055 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 9059293 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27298017 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 23765950 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9085297 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9085297 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31301210 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31301210 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29429138 — Biomarker: KCNQ1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNQ1; KCNA8; KCNA9; KVLQT1
Study 29429138 — Biomarker: KCNH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNH2; ERG; ERG1; HERG
Study 29429138 — Biomarker: SCN5A mRNA
Type: Predictive Biomarker (PRD)
Genes: SCN5A
Study 29429138 — Biomarker: NOS1AP mRNA
Type: Predictive Biomarker (PRD)
Genes: NOS1AP; CAPON; KIAA0464
Study 29429138 — Biomarker: NUBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: NUBPL; C14orf127
Study 24513787 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 23056520 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 12784968 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 30649058 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30649058 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19101754 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15258682 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15258682 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18759644 — Biomarker: CGAS mRNA
Type: Predictive Biomarker (PRD)
Genes: CGAS; C6orf150; MB21D1
Study 31831255 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31831255 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 31831255 — Biomarker: Cathepsin S
Type: Pharmacodynamic Biomarker (PDY)
Genes: CTSS
Study 31831255 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30870970 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21996047 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 21996047 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 21996047 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16414215 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 16414215 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16414215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8808491 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15629215 — Biomarker: FMR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMR1
Study 15629215 — Biomarker: FMR1
Type: Predictive Biomarker (PRD)
Genes: FMRP; FRAXA; MGC87458
Study 12131220 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23340533 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 23340533 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 8270721 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 2826550 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25403867 — Biomarker: CHIA mRNA
Type: Predictive Biomarker (PRD)
Genes: CHIA
Study 25403867 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 25403867 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10860034 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 41229 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28812321 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24002093 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24002093 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 24002093 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19747876 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7803722 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29175149 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29175149 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 28526536 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12940872 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6205337 — Biomarker: BLM mRNA
Type: Predictive Biomarker (PRD)
Genes: BLM; RECQ2; RECQL3
Study 29659797 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23336612 — Biomarker: ARHGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARHGEF5; TIM
Study 15643230 — Biomarker: Bcl-2 to Bax
Type: Pharmacodynamic Biomarker (PDY)
Study 1360665 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25560349 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31959139 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27940700 — Biomarker: FANCE mRNA
Type: Predictive Biomarker (PRD)
Genes: FANCE; FACE
Study 15859929 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 2534373 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26276354 — Biomarker: PLXNA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 26276354 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26276354 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 21720704 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 14524509 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 11109647 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9019177 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27865961 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 27865961 — Biomarker: GRAP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRAP2; GADS; GRB2L; GRID
Study 7620297 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26168277 — Biomarker: BMAL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BMAL1; ARNTL; BHLHE5; MOP3; PASD3
Study 26168277 — Biomarker: CRY1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CRY1; PHLL1
Study 26168277 — Biomarker: PER1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PER1; KIAA0482; PER; RIGUI
Study 21736785 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 21736785 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14623528 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 2859780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12851303 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12851303 — Biomarker: MC3R mRNA
Type: Predictive Biomarker (PRD)
Genes: MC3R
Study 29046405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26639851 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 23092731 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21823168 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21823168 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16202727 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16202727 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2968268 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11755292 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11720604 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 381957 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 381957 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31544279 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 26177655 — Biomarker: CD200R1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD200R1; CD200R; CRTR2; MOX2R; OX2R; UNQ2522/PRO6015
Study 23920052 — Biomarker: TMEM176B mRNA
Type: Predictive Biomarker (PRD)
Genes: TMEM176B; LR8
Study 30305160 — Biomarker: LAMB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMB2; LAMS
Study 24844747 — Biomarker: SLC6A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A1; GABATR; GABT1; GAT1
Study 22825365 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 20116087 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16181235 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16181235 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16181235 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18801487 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 9951916 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 2853753 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2853753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1841828 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28142202 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20941459 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 20941459 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24557659 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study 18936501 — Biomarker: NPL mRNA
Type: Predictive Biomarker (PRD)
Genes: NPL; C1orf13
Study 10100064 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8889438 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 25376862 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 7570567 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 19118083 — Biomarker: CYP4F2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP4F2
Study 9336420 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3542323 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 25164220 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 9374447 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27824811 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 21803547 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12566747 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 9585793 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 31345107 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31345107 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28430522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25746727 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1646259 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28881147 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 28881147 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28881147 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 24576517 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22510506 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 22510506 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 10575655 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 10575655 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30514777 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 29110641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26205609 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 23917472 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22001911 — Biomarker: KDM5D mRNA
Type: Predictive Biomarker (PRD)
Genes: KDM5D; HY; HYA; JARID1D; KIAA0234; SMCY
Study 19161480 — Biomarker: LRIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LRIT1; LRRC21; PAL
Study 17541944 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11920413 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2254718 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15450782 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 15450782 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 15450782 — Biomarker: GAD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD2; GAD65
Study 11229823 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 11229823 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9893913 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9893913 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25983669 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19687350 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19687350 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11069800 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11069800 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 9263752 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 9263752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28361113 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 9232359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2866932 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2866932 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22539545 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22539545 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20146685 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 17118822 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 20106646 — Biomarker: PCSK7 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK7; LPC; PC7; PC8; SPC7