AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 19149837 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19149837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17017752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17017752 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23279918 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 9760818 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7533224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29193419 — Biomarker: TCF7L2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCF7L2; TCF4
Study 29193419 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 23278371 — Biomarker: MLXIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MLXIP; BHLHE36; KIAA0867; MIR; MONDOA
Study 17434171 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 16868496 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8712737 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 1781870 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21543293 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16508254 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 11126172 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 3490992 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 3490992 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24941835 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 24941835 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 24941835 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22512510 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 18254721 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24937510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20499203 — Biomarker: PDPR mRNA
Type: Predictive Biomarker (PRD)
Genes: PDPR; KIAA1990
Study 9052357 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 3670227 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31373922 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21948782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25190051 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 14679153 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29121979 — Biomarker: PSD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSD4; EFA6B; TIC
Study 21251179 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15034229 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 26561314 — Biomarker: MTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 18721739 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18721739 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11039742 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4035232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30021886 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30021886 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 30021886 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30021886 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study 30021886 — Biomarker: HLA-C
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HLA-JY3, D6S204, PSORS1
Study 30641625 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30641625 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30641625 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 20173020 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20173020 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20173020 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20173020 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12443837 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 12443837 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2571203 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 23060056 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 21903774 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 21903774 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 12862201 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12862201 — Biomarker: Serum hemoglobin A1C
Type: Surrogate Endpoint (SUR)
Study 24389520 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11187868 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 11187868 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 28201994 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30105266 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 30105266 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 26653067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20121764 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 7023522 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7023522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29935595 — Biomarker: CHRM3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRM3
Study 20619512 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 25934044 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 10359410 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1850691 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 6121836 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23054802 — Biomarker: SSB mRNA
Type: Predictive Biomarker (PRD)
Genes: SSB
Study 8294618 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 18469237 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 18469237 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 17472154 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16388166 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16388166 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31584516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26626993 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 26626993 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 26626993 — Biomarker: TET2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET2; KIAA1546; Nbla00191
Study 26626993 — Biomarker: DNMT3A mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMT3A
Study 26626993 — Biomarker: ASXL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASXL1; KIAA0978
Study 25574674 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22716474 — Biomarker: NRXN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRXN3; KIAA0743
Study 20401289 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 6088019 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 27656953 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21040410 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12237663 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12237663 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 28000620 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 20144207 — Biomarker: CCR3 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CCR3; CMKBR3
Study 20144207 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 18194848 — Biomarker: POLI mRNA
Type: Predictive Biomarker (PRD)
Genes: POLI; RAD30B
Study 15938033 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 15938033 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12736473 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24857051 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9799980 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30657120 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26123919 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19594864 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23350342 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12441260 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 12441260 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 10515844 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 1723464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27930529 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24584549 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 24584549 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15763054 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15763054 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12428174 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28028150 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 10418043 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31863599 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 31863599 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 27779456 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 27779456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7986467 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26296647 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30067600 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19422355 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2872717 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 30124726 — Biomarker: FGFR1
Type: Predictive Biomarker (PRD)
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 26795846 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 26795846 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 20890191 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20890191 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 20890191 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 20890191 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 20890191 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 20890191 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16194413 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16194413 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16194413 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2983910 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30245755 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30245755 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 30245755 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 30245755 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 24903081 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20145666 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10486663 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29953482 — Biomarker: RYR1
Type: Safety Biomarker (SAF)
Genes: RYR; PPP1R137
Study 22797934 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 2392791 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28574408 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21441444 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 21441444 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17275744 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11730653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28959813 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 18787327 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16669846 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 12797494 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 12797494 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 31113362 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 15675575 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 2206036 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2206036 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28768451 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 23415311 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23459334 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 12631051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10671927 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4030197 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18508946 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2647051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25450818 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 25450818 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16948809 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 11380515 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3471304 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 14557449 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11099619 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27009620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27009620 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20142543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20142543 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10703876 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1718158 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 9227164 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7958497 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 7958497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30977767 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 30977767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12796026 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 12796026 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 6941637 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18244953 — Biomarker: CCR3 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CCR3; CMKBR3
Study 12591752 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8671971 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 8671971 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8671971 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1768565 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8500867 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30789808 — Biomarker: AIP mRNA
Type: Predictive Biomarker (PRD)
Genes: AIP; XAP2
Study 30789808 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 18294323 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 3516077 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19699885 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11873095 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8141163 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1920342 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 26684708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19386744 — Biomarker: MGP mRNA
Type: Predictive Biomarker (PRD)
Genes: MGP; MGLAP; GIG36
Study 16690701 — Biomarker: PLN mRNA
Type: Predictive Biomarker (PRD)
Genes: PLN; PLB
Study 26286662 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 26286662 — Biomarker: MARCKS mRNA
Type: Predictive Biomarker (PRD)
Genes: MARCKS; MACS; PRKCSL
Study 2904373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11443568 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 11443568 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 31625947 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 19023677 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15017629 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 9347286 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 30944103 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 24687088 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 15973964 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15973964 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 18593759 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11453961 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 7687717 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24217262 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16525677 — Biomarker: CARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARS1; CARS
Study 16525677 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 30111284 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23078110 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23078110 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 23078110 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 23078110 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 9268188 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 9268188 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9268188 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 10588299 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 1713753 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1713753 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31409388 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study 19247842 — Biomarker: IPP mRNA
Type: Predictive Biomarker (PRD)
Genes: IPP; KLHL27
Study 19247842 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15657667 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22865266 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5