AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 29310611 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30178473 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26731173 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 11922259 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9849707 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27354031 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 11158455 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2102029 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 939029 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25728015 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3236382 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25178692 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 12538778 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 8752181 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 1460163 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 1460163 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 30676094 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 30650291 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 12560354 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 7791169 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2289220 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31255504 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 10972631 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26352063 — Biomarker: TTN mRNA
Type: Predictive Biomarker (PRD)
Genes: TTN
Study 16412324 — Biomarker: SRY mRNA
Type: Predictive Biomarker (PRD)
Genes: SRY; TDF
Study 16412324 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 29367197 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 29367197 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 29367197 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 29367197 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 29367197 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 26589368 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26589368 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24706353 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24706353 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23964445 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7045365 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25682436 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23066159 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 9809088 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7544439 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 31594858 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 28246176 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 24565127 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24565127 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17966842 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 17966842 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9534083 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9534083 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 22025233 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18458360 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18458360 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 22402472 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22402472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20304805 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 20304805 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study 16476804 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2409325 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 29498170 — Biomarker: DBH mRNA
Type: Predictive Biomarker (PRD)
Genes: DBH
Study 27920083 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27920083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22790645 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 25948781 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8306514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3028596 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 22088980 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 16046076 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1286181 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 1286181 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30046828 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30046828 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8063650 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8063650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23391421 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23391421 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 23391421 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 23391421 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 21573977 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 28653239 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 12360153 — Biomarker: ACAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAT1; ACAT; MAT
Study 30573355 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 27776459 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27776459 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2837300 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2837300 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23997711 — Biomarker: MXD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MXD1; MAD
Study 23997711 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16314615 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 12846491 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 12846491 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 31702684 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 25782660 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 23280432 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21885491 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12692541 — Biomarker: FUT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FUT2; SEC2
Study 7788003 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7788003 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2195937 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 29118299 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 22569355 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17803575 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 11952478 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 11952478 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 11952478 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2645756 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2645756 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2645756 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 21875678 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 17201083 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 1913759 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6814225 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26377322 — Biomarker: CPQ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPQ; LCH1; PGCP
Study 15208206 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24176436 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17257782 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 10467322 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 8751023 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25457902 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 1316404 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1316404 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28361971 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 28361971 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28361971 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28361971 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17111319 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17111319 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 23448278 — Biomarker: CCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR4; CMKBR4
Study 23448278 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC
Study 18353720 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 10869261 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 2580694 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 22709755 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 7814484 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 29400990 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28611235 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 28611235 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 21901266 — Biomarker: HSPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPB1; HSP27; HSP28
Study 9839627 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 9839627 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 2520633 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23816952 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17005526 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17005526 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 15021447 — Biomarker: SERPINA7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA7; TBG
Study 15021447 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 15021447 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 11710752 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31087825 — Biomarker: PPP1R9B mRNA
Type: Predictive Biomarker (PRD)
Genes: PPP1R9B; PPP1R6
Study 24916903 — Biomarker: DLG4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DLG4; PSD95
Study 24916903 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 18409186 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 18409186 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 30854694 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 16224147 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 12362542 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26102724 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26102724 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15158606 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 18487901 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 16822626 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 15298339 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15298339 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 11204933 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27683100 — Biomarker: ETV6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV6; TEL; TEL1
Study 27683100 — Biomarker: RUNX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX1; AML1; CBFA2
Study 9440475 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18224563 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 16998452 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 12729085 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 24519386 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20945945 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 10870655 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 8692118 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 25511777 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 20185862 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 20185862 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8726246 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 23775701 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22828718 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15163472 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15163472 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11334767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2832173 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2832173 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27942799 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 20860641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16455626 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 14514236 — Biomarker: SPTB mRNA
Type: Predictive Biomarker (PRD)
Genes: SPTB; SPTB1
Study 1497054 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 30243898 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30243898 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27227930 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 10232636 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 29543617 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19083486 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16545010 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8269792 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8269792 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21645443 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 16598319 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16598319 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 18355134 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 18355134 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31790905 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21319354 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 21319354 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21319354 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19101790 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16879516 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16879516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22619366 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 26767971 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26767971 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 26767971 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 22278425 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 22278425 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 17640790 — Biomarker: MAOB mRNA
Type: Predictive Biomarker (PRD)
Genes: MAOB
Study 7744989 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 2033780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7305036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28503781 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 28503781 — Biomarker: SLCO1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 28503781 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 21401909 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12607857 — Biomarker: TBP mRNA
Type: Predictive Biomarker (PRD)
Genes: TBP; GTF2D1; TF2D; TFIID
Study 9208536 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 3481821 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19841156 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 11844946 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 25328284 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 20828223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25847558 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 15134386 — Biomarker: LYST mRNA
Type: Predictive Biomarker (PRD)
Genes: LYST; CHS; CHS1
Study 11822472 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11822472 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 8043891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2462651 — Biomarker: REG3A mRNA
Type: Predictive Biomarker (PRD)
Genes: REG3A; HIP; PAP; PAP1
Study 25377507 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25377507 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21600163 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21600163 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10716135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9178399 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1283198 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 29802443 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 10596917 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 1714948 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 26265232 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17132823 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21679323 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)