AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23274785 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 23274785 — Biomarker: OPN1SW mRNA
Type: Predictive Biomarker (PRD)
Genes: OPN1SW; BCP
Study 23274785 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 21649862 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11709742 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 7815279 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16335673 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15300231 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 3313041 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30931750 — Biomarker: Hydroxyphenylpyruvate dioxygenase
Type: Safety Biomarker (SAF)
Genes: HPD; PPD
Study 21122466 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 21122466 — Biomarker: DUSP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DUSP2; PAC1
Study 21122466 — Biomarker: MZB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MZB1; MEDA7; PACAP; HSPC190
Study 29973132 — Biomarker: Plasma testosterone level
Type: Surrogate Endpoint (SUR)
Study 20185423 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 16213926 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 8838703 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16173650 — Biomarker: MT2A mRNA
Type: Predictive Biomarker (PRD)
Genes: MT2A; CES1; MT2
Study 12930012 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 12930012 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 10830792 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29228091 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22492249 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 17040305 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 12968984 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12968984 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 8473654 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8473654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24024773 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19296254 — Biomarker: ASPRV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASPRV1; SASP
Study 19296254 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12126263 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12126263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9651560 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9638202 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 17116177 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17116177 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31856493 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18074471 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18074471 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9972958 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 2283638 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6118715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6118715 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 19739937 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19739937 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12682418 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8561064 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8561064 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29260703 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10908255 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 9302398 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29797911 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29797911 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23338230 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 21304082 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 16424704 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 12670811 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12670811 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 29305709 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29305709 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 29305709 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 15771635 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 23917775 — Biomarker: TLR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR1; KIAA0012
Study 16807414 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12681523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11382829 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11382829 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11382829 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 3438580 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study 3438580 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30716679 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30716679 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30716679 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25475658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25475658 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25475658 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8763802 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17085458 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9361690 — Biomarker: PZP mRNA
Type: Predictive Biomarker (PRD)
Genes: PZP; CPAMD6
Study 27710596 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23321990 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 29940952 — Biomarker: miR-206
Type: Safety Biomarker (SAF)
Genes: MIR206
Study 29940952 — Biomarker: miR-146b
Type: Safety Biomarker (SAF)
Genes: MIR146B
Study 27184170 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2671112 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 12745200 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12745200 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2421120 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 27855365 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 22614972 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 20485161 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 20485161 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15695321 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 8747987 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 24256611 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 24256611 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 24256611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20414536 — Biomarker: CPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPB1; CPB; PCPB
Study 12133397 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24026523 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 23241242 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15308586 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20832550 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 18607338 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 8927676 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 31026780 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 26739392 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26739392 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21290836 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 7640145 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2502417 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 15124952 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 11818767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15648125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8989272 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27178897 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22470429 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21103404 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 11700410 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 11700410 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11700410 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11700410 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 3316301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28939617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24391801 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21189401 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8147043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24710760 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22277987 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22277987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20350191 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12841887 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12841887 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10597781 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28671000 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 28671000 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 25644619 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 21791543 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3289524 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 29848361 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 17375114 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10643851 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9191873 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9191873 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 9191873 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 28639554 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21118175 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16603801 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22966009 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 22966009 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20451686 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20451686 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28796588 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 28796588 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 19744307 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30929657 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 23503447 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 23503447 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 23503447 — Biomarker: NR1I2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1I2; PXR
Study 23503447 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 23503447 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 11729740 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 3981950 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 21545249 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15563344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25348255 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21341397 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8995995 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 8995995 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8355469 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8355469 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8355469 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28868878 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18401223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30393935 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 20178395 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20178395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28192225 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 24373064 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10783213 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10783213 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8624314 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3886402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27542517 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 27542517 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 10080835 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10080835 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 7590403 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7590403 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7590403 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 7428446 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7428446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26177480 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 26177480 — Biomarker: CDA
Type: Safety Biomarker (SAF)
Genes: CDD
Study 19597420 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19597420 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 15353916 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30234480 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22775125 — Biomarker: EDA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDA; ED1; EDA2
Study 9924274 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 29676968 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 29676968 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29676968 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27380030 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 23312049 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20107154 — Biomarker: AFF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AFF1; AF4; FEL; MLLT2; PBM1
Study 17086009 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14506629 — Biomarker: TRO mRNA
Type: Predictive Biomarker (PRD)
Genes: TRO; KIAA1114; MAGED3
Study 1717789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25686683 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21536199 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 15614029 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15614029 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 15614029 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25494343 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 21850019 — Biomarker: TLR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR7; UNQ248/PRO285
Study 21850019 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21850019 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20303641 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 19139601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8979626 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8979626 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30121686 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24569127 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 24569127 — Biomarker: PLXNA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 24569127 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 11967633 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 31088530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27733466 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19213769 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 14977771 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 18512165 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30967099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25997508 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 19567246 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 16397129 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 9160765 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2965232 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 27355499 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16337041 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 16337041 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 14602767 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31467510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16024131 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12538212 — Biomarker: EDA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDA; ED1; EDA2
Study 10215195 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 26537937 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15982658 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 15982658 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1