AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 14759453 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 14759453 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 14759453 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3549083 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17586139 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 17586139 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 12075915 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10605950 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10605950 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 25387477 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16076944 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10404735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7590502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6766833 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 31332998 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 25878177 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 27757829 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27757829 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23937012 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15139978 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31542965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17355732 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11996956 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11996956 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23810626 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20085534 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8997168 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8997168 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 6712863 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30824398 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18485759 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 15851366 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15851366 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25546001 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 23630016 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 7922794 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 25904376 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 25904376 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 25904376 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 25904376 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 25904376 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19266214 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19266214 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19266214 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23577719 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 23577719 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22010914 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31232275 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 27885712 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27885712 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 27885712 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 27885712 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16823726 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 23803696 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 23803696 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 23803696 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 23803696 — Biomarker: MYD88 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYD88
Study 22032072 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29697830 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 12962794 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 23599623 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23599623 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 23599623 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19289857 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27004531 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23511711 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 18387161 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 18387161 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 6356855 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31857319 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 18628467 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 15959537 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11840030 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 2521997 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2521997 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26972358 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 24716681 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 22425308 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18079051 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11423583 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8994481 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7957469 — Biomarker: CEACAM6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CEACAM6; NCA
Study 31748467 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30972995 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 1318281 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26963316 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 25130297 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 383417 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26140739 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21134995 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21134995 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 23735746 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9005419 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9005419 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 2072371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28961833 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 28961833 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28961833 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 28961833 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 28961833 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 19416946 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 19416946 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9555954 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8956759 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 2951800 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2951800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30012361 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 30012361 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 22704111 — Biomarker: Activated leukocyte cell adhesionmolecule
Type: Predictive Biomarker (PRD)
Genes: ALCAM; MEMD
Study 18711169 — Biomarker: PITX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PITX2; ARP1; RGS; RIEG; RIEG1
Study 18711169 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 1330411 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25550339 — Biomarker: Complete renal response
Type: Surrogate Endpoint (SUR)
Study 22331646 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22331646 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19289319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11529904 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 3278190 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3278190 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 10904511 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8363025 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28522130 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29152839 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 24023271 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20461009 — Biomarker: MUC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MUC2; SMUC
Study 20461009 — Biomarker: Trefoil factor 3
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TFF3; ITF; TFI
Study 31183985 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 19733719 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19733719 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10212375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19167814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11756319 — Biomarker: SLC2A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A1; GLUT1
Study 11756319 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 2655688 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21349458 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24009042 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 24009042 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 24009042 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 20972299 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19260871 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 28051345 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28051345 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 21982167 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 28187765 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28187765 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28187765 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23377391 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 15340332 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11938803 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11938803 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1383924 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 1383924 — Biomarker: OPRM1
Type: Safety Biomarker (SAF)
Genes: MOR1; MOP
Study 28651616 — Biomarker: PTGDS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGDS; PDS
Study 25481367 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25481367 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 25481367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21493022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14760156 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 28399028 — Biomarker: ERBIN mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBIN; ERBB2IP; KIAA1225; LAP2
Study 26665553 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26665553 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21638037 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21638037 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21638037 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12927315 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 18506154 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study 11451757 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24366725 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 15356071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2675962 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 2675962 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 25361738 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 24268098 — Biomarker: ANKS4B mRNA
Type: Predictive Biomarker (PRD)
Genes: ANKS4B; HARP
Study 19755964 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11846847 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 9885792 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8771612 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 25212696 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19102515 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15219499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9469527 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 9469527 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 29535130 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 10339732 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8984131 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8984131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24840781 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17019594 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17019594 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28855976 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 26547357 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11237920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30666023 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17721621 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 15982605 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15982605 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20639712 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 16644278 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 10831925 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1346182 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6202963 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29947235 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29947235 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 12808486 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12808486 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12808486 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12808486 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12808486 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 16360360 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16360360 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16360360 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 12058096 — Biomarker: EEF1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EEF1A2; EEF1AL; STN
Study 1483483 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2990711 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 10190404 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23230311 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23230311 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23230311 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 15174325 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 11697832 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 31901710 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31901710 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31901710 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28382551 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25719419 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 17034279 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 12514268 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12514268 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 12514268 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 10882617 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31250552 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31250552 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31250552 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 31250552 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29363988 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29363988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18280335 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 12679443 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 16339498 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2