AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 28841389 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 28841389 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 28841389 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 28841389 — Biomarker: MAP2K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K1; MEK1; PRKMK1
Study 28841389 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 28841389 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 28841389 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28841495 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28841744 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 28844410 — Biomarker: PAG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAG1; CBP; PAG
Study 28844410 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 28845238 — Biomarker: Auditory mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 28845238 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 28845508 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28846559 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28846953 — Biomarker: WT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WT1
Study 28847911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28847911 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 28848672 — Biomarker: HSPA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA5; GRP78
Study 28850430 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 28851109 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 28851380 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 28851380 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 28851380 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 28851416 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 28851415 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28851415 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28851423 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 28851447 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 28851781 — Biomarker: SLC25A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A3; PHC; OK/SW-cl.48
Study 28851978 — Biomarker: TRAPPC9 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 28854543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28854726 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28856009 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28857778 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28857822 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 28859185 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study 28859325 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28860342 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 28860342 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 28861121 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 28862877 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 28862877 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 28865109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28865109 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28866117 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28866726 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28866779 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 28867340 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 28867665 — Biomarker: ABCC9 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC9; SUR2
Study 28867665 — Biomarker: ABCC12 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC12; MRP9
Study 28867665 — Biomarker: SLC28A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC28A1; CNT1
Study 28867665 — Biomarker: Peroxisome proliferator-activated receptor delta
Type: Safety Biomarker (SAF)
Genes: PPARD
Study 28869790 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28869790 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28869790 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 28869790 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 28869931 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 28870611 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 28870611 — Biomarker: miR-16
Type: Safety Biomarker (SAF)
Study 28870611 — Biomarker: miR-15
Type: Safety Biomarker (SAF)
Study 28870615 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28870716 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28871441 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28872549 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28874132 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28874669 — Biomarker: YAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: YAP1; YAP65
Study 28877686 — Biomarker: HOXA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: HOXA3; HOX1E
Study 28877686 — Biomarker: HOXA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: HOXA4; HOX1D
Study 28877686 — Biomarker: HOXA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: HOXA5; HOX1C
Study 28877686 — Biomarker: PBX3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX3
Study 28877686 — Biomarker: DNMT3A mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMT3A
Study 28877686 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 28878934 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 28879040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28879043 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28879248 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 28879248 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 28879247 — Biomarker: JPH2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: JPH2; JP2
Study 28880374 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 28881319 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 28881839 — Biomarker: AADAC mRNA
Type: Predictive Biomarker (PRD)
Genes: AADAC; DAC
Study 28882436 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 28882436 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 28883894 — Biomarker: MAP3K7 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP3K7; TAK1
Study 28883894 — Biomarker: MYD88 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYD88
Study 28883894 — Biomarker: Interleukin 6 receptor alpha
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: IL6R
Study 28883894 — Biomarker: RIPK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RIPK2; CARDIAK; RICK; RIP2; UNQ277/PRO314/PRO34092
Study 28883894 — Biomarker: FADD mRNA
Type: Predictive Biomarker (PRD)
Genes: FADD; MORT1; GIG3
Study 28883894 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 28885930 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28887375 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 28889107 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 28892218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28894792 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 28898890 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28899363 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 28899363 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28899517 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28900115 — Biomarker: Argininosuccinate synthase
Type: Safety Biomarker (SAF)
Genes: ASS1; ASS
Study 28900115 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 28903941 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28903943 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 28903943 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 28905294 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 28911136 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 28911922 — Biomarker: RAF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAF1; RAF
Study 28911922 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 28912030 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28912804 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study 28912956 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28916584 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 28916600 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28916979 — Biomarker: P4HB mRNA
Type: Predictive Biomarker (PRD)
Genes: P4HB; ERBA2L; PDI; PDIA1; PO4DB
Study 28917612 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 28917673 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 28919031 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 28919454 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 28921760 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 28921872 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 28921872 — Biomarker: TERT mRNA
Type: Predictive Biomarker (PRD)
Genes: TERT; EST2; TCS1; TRT
Study 28921872 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 28921907 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 28921907 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 28922466 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 28923060 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28923290 — Biomarker: TAS2R60 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAS2R60
Study 28923290 — Biomarker: TRPM8 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPM8; LTRPC6; TRPP8
Study 28923760 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 28923845 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 28924018 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 28924018 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28925785 — Biomarker: NOTCH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOTCH1; TAN1
Study 28926513 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28928173 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28934680 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 28934680 — Biomarker: JAK2
Type: Predictive Biomarker (PRD)
Genes: JTK10
Study 28938424 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28938424 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28938478 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 28938478 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 28939374 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28939546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28939558 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 28939558 — Biomarker: RAF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAF1; RAF
Study 28939688 — Biomarker: C1QL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 28940455 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 28941036 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 28941620 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 28943279 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 28943493 — Biomarker: SFMBT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SFMBT2; KIAA1617
Study 28943493 — Biomarker: SESN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SESN3; SEST3
Study 28943493 — Biomarker: SEC62 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEC62; TLOC1
Study 28944714 — Biomarker: GLS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS2; GA
Study 28945848 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 28945911 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 28945911 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 28948656 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28950146 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28950146 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 28950288 — Biomarker: MAP2K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K1; MEK1; PRKMK1
Study 28950290 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 28950290 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28950298 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28950309 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 28950338 — Biomarker: NRG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study 28950338 — Biomarker: SDC4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SDC4
Study 28950338 — Biomarker: ATP1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATP1B1; ATP1B
Study 28950372 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 28950889 — Biomarker: Mitochondrial frataxin
Type: Monitoring Biomarker (MOI)
Genes: FXN; FRDA; X25
Study 28951660 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 28952191 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 28954004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28954285 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 28954285 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28954285 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 28954285 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 28954285 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 28954285 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 28954781 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 28955494 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 28955496 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28956082 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 28956082 — Biomarker: CHGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CHGA
Study 28956082 — Biomarker: GCG mRNA
Type: Predictive Biomarker (PRD)
Genes: GCG
Study 28956082 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 28956082 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 28956082 — Biomarker: PCSK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK1; NEC1
Study 28956082 — Biomarker: PCSK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK2; NEC2
Study 28958347 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 28958801 — Biomarker: PAFAH1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study 28958801 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 28959122 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28959500 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study 28960096 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 28961812 — Biomarker: CTRC mRNA
Type: Predictive Biomarker (PRD)
Genes: CTRC; CLCR
Study 28961847 — Biomarker: DNA mismatch repair protein MSH2
Type: Predictive Biomarker (PRD)
Genes: MSH2
Study 28961847 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 28962047 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 28962047 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 28964326 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 28964701 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 28964736 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 28964736 — Biomarker: APOB mRNA
Type: Predictive Biomarker (PRD)
Genes: APOB
Study 28964736 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 28965093 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28965185 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study 28965778 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 28970100 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 28970192 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 28971223 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 28971900 — Biomarker: MTOR
Type: Predictive Biomarker (PRD)
Genes: RAFT1; RAPT1; FLJ44809
Study 28972011 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 28972913 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28973026 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 28973026 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28973026 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28973091 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 28973164 — Biomarker: miR-375
Type: Safety Biomarker (SAF)
Genes: MIR375
Study 28973223 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28973223 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 28973403 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 28973622 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 28976556 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 28976556 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 28976817 — Biomarker: ABCD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCD1; ALD
Study 28976817 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 28978551 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 28978797 — Biomarker: TACR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TACR1; NK1R; TAC1R
Study 28978797 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28978797 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 28980004 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 28980198 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28980446 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 28981994 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 28981994 — Biomarker: AKR1C3 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKR1C3; DDH1; HSD17B5; KIAA0119; PGFS
Study 28981994 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 28982159 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28982374 — Biomarker: PTBP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTBP2; NPTB; PTB; PTBLP
Study 28982667 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28982765 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 28982765 — Biomarker: SH2D2A mRNA
Type: Predictive Biomarker (PRD)
Genes: SH2D2A; SCAP; TSAD; VRAP
Study 28983018 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2