AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31586420 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30860570 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 30860570 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30860570 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21602474 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21602474 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19635148 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19635148 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12468560 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29945920 — Biomarker: IKZF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IKZF1; IK1; IKAROS; LYF1; ZNFN1A1
Study 29945920 — Biomarker: IKZF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IKZF3; ZNFN1A3
Study 29945920 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 22360996 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31035054 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 31035054 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15878754 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15878754 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25694481 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 25694481 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23496006 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18379535 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16802519 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8095240 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20819314 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 3138441 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28520754 — Biomarker: NFKB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NFKB1
Study 28520754 — Biomarker: NFKB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NFKB2; LYT10
Study 15593020 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11437859 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11437859 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 11437859 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11437859 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 25327942 — Biomarker: DCC mRNA
Type: Predictive Biomarker (PRD)
Genes: DCC; IGDCC1
Study 20816039 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 18427147 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16532712 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16532712 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16532712 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12692113 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 20039429 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 17321816 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 11605744 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11605744 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11819342 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11819342 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30817465 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25923550 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23889096 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12074359 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24063362 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26617135 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12560435 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18406045 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 3533561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25282031 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19607755 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 19607755 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 12189442 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8596497 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8596497 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1431597 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30368585 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 27169834 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 23101480 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 15452671 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23351825 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17296460 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17296460 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22248500 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19070995 — Biomarker: CDS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDS1; CDS
Study 19070995 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23587747 — Biomarker: GCA mRNA
Type: Predictive Biomarker (PRD)
Genes: GCA; GCL
Study 9204354 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29236711 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12447010 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9583368 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9583368 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 25837215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25837215 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18655566 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 18655566 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 16959188 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6115001 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 31090511 — Biomarker: INPP5D mRNA
Type: Predictive Biomarker (PRD)
Genes: INPP5D; SHIP; SHIP1
Study 25125635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9459393 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16353581 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3356082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27752170 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18093197 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 12166353 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2912000 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31128057 — Biomarker: MYCN mRNA
Type: Predictive Biomarker (PRD)
Genes: MYCN; BHLHE37; NMYC
Study 26329838 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 26329838 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19298231 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 19298231 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 19298231 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 28154796 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 25993119 — Biomarker: IFNAR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNAR1; IFNAR
Study 21775147 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17584698 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 17584698 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17584698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15201999 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2227074 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27634419 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 24716610 — Biomarker: FGF7 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF7; KGF
Study 24716610 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24716610 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19390327 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15450725 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 15450725 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 9746769 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 9746769 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 27271190 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18572079 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 12903826 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 12903826 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12903826 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30336598 — Biomarker: FER mRNA
Type: Predictive Biomarker (PRD)
Genes: FER; TYK3
Study 11127445 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11127445 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7746415 — Biomarker: PRF1
Type: Predictive Biomarker (PRD)
Genes: PFP; P1; HPLH2
Study 31875053 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28008750 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28008750 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 28008750 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 28008750 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19288149 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15599835 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11056773 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11056773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2976670 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16356485 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 16356485 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 16356485 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 16356485 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 16356485 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 16356485 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 16356485 — Biomarker: SLCO1B3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 16356485 — Biomarker: SLCO2B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 16356485 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 16356485 — Biomarker: ABCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 16356485 — Biomarker: PLXNA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 8645023 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 8645023 — Biomarker: TYMS
Type: Predictive Biomarker (PRD)
Genes: Tsase; TMS; HsT422
Study 30915366 — Biomarker: MSN mRNA
Type: Predictive Biomarker (PRD)
Genes: MSN
Study 20025149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17998767 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 1221110 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15213322 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15213322 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 10074978 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 29600390 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24570327 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22024226 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19195791 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 6406654 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29463485 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29463485 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25614155 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 21508862 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 21508862 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 15200652 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15200652 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11158224 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11158224 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25534866 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study 22088245 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 22088245 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 14506194 — Biomarker: Carbonic anhydrase IX
Type: Predictive Biomarker (PRD)
Genes: CA9; G250; MN
Study 10202987 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7636648 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 31685356 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31685356 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31685356 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21334626 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15145924 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 2897763 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27472020 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14734593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9469533 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 7940682 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 7940682 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28286115 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 17420513 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 15891590 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27184784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25402666 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 22985565 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18570599 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 12478147 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 10718909 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30623236 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 10511390 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26437056 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26437056 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 26784137 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 20300015 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 18259010 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11443189 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11443189 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11443189 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11443189 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7958119 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 3314464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31530820 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31530820 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29946969 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29946969 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26573073 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 12235653 — Biomarker: NOCT mRNA
Type: Predictive Biomarker (PRD)
Genes: NOCT; CCR4; CCRN4L; NOC
Study 10460065 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 11181810 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8220653 — Biomarker: SLC6A7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A7; PROT
Study 30071838 — Biomarker: FGA mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGA
Study 8636825 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28931520 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28931520 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 21411093 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 21411093 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21411093 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18775100 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18775100 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study 15770057 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15770057 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10453777 — Biomarker: PTPRF mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRF; LAR
Study 19147974 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8993250 — Biomarker: CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR1; C3BR
Study 8181028 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2955799 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 29866187 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29866187 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20560981 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7979285 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31009834 — Biomarker: COPE mRNA
Type: Predictive Biomarker (PRD)
Genes: COPE
Study 28152251 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 779588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28838980 — Biomarker: APC
Type: Safety Biomarker (SAF)
Genes: DP2; DP3; DP2.5; PPP1R46
Study 11208880 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 1515565 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR