AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 2147014 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 21321791 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11294692 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12520257 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 17579637 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 17579637 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 31621175 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 23623526 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 10742366 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8923861 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18031592 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15963388 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15963388 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15963388 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15963388 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12502980 — Biomarker: PPIA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPIA; CYPA
Study 12502980 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12502980 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11022186 — Biomarker: HHEX mRNA
Type: Predictive Biomarker (PRD)
Genes: HHEX; HEX; PRH; PRHX
Study 1803848 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 31924318 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31924318 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31041925 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25140763 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25140763 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 16651474 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12631093 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12631093 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6702866 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 6702866 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21868715 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 19169664 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 19169664 — Biomarker: ADIPOR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOR2; PAQR2
Study 8641739 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 6744780 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6744780 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21041592 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18192924 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25536449 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 20521648 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 9461709 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9461709 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9461709 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3259681 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 28134672 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21794843 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 21794843 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 11404533 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21198566 — Biomarker: CSAD mRNA
Type: Predictive Biomarker (PRD)
Genes: CSAD; CSD
Study 6992823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22248762 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 7889183 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 17604912 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 10370679 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15295690 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12566370 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10356958 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 31663683 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23668675 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23668675 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23668675 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 23668675 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 23668675 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28093841 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28093841 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19318434 — Biomarker: PARP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PARP1; ADPRT; PPOL
Study 19318434 — Biomarker: ERCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC2; XPD; XPDC
Study 19318434 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 19318434 — Biomarker: BICRA mRNA
Type: Predictive Biomarker (PRD)
Genes: BICRA; GLTSCR1
Study 27321312 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 9535153 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2533042 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31813636 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 17236889 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15590583 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 9306340 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3737444 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27891769 — Biomarker: NREP mRNA
Type: Predictive Biomarker (PRD)
Genes: NREP; C5orf13; P311
Study 24266969 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 15561052 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 8529331 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7748051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7748051 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31454046 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11150025 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 31128008 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 12780755 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 8939767 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11176979 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 23205735 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 23507132 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 10836778 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8384054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27776764 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 24849104 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 12563622 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 10546919 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 6439144 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 26488759 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 22326210 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 8583793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6277642 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 30251205 — Biomarker: ASXL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASXL2; ASXH2; KIAA1685
Study 30251205 — Biomarker: ZBTB7A mRNA
Type: Predictive Biomarker (PRD)
Genes: ZBTB7A; FBI1; LRF; ZBTB7; ZNF857A
Study 30251205 — Biomarker: RUNX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX1; AML1; CBFA2
Study 30251205 — Biomarker: RUNX1T1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study 30251205 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 26113580 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11740193 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9922474 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22770506 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 21467231 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 7883394 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 7883394 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7883394 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 27342073 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16085220 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11918622 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19039596 — Biomarker: PDPR mRNA
Type: Predictive Biomarker (PRD)
Genes: PDPR; KIAA1990
Study 17503885 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 12373268 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 26761561 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19910566 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 19910566 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19910566 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19910566 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19910566 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19910566 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19910566 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 19910566 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 15515332 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 29578097 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 18364502 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 16293958 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12749746 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7744141 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 25592552 — Biomarker: RFC1
Type: Safety Biomarker (SAF)
Genes: A1; PO-GA; RFC140; MHCBFB
Study 9474311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7940435 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 25622729 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 25622729 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23052930 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18223611 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1279279 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1279279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22333698 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 18319360 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 18319360 — Biomarker: MRP2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ABCC2; DJS; cMRP
Study 18319360 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 11990003 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7477168 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7444552 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26997243 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 18033754 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 18033754 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 27825616 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 26397228 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10971248 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12676074 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1829372 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 1829372 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29880047 — Biomarker: PRKRA mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKRA; PACT; RAX; HSD-14; HSD14
Study 27253829 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 11329231 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11329231 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9291302 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 11555165 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22549090 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22549090 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study 19733353 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 30043183 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 30043183 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 30043183 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 30043183 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25198268 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 21148614 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29505867 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12384647 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27630504 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 23249098 — Biomarker: NFIC mRNA
Type: Predictive Biomarker (PRD)
Genes: NFIC; NFI
Study 11914244 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 2605801 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26047470 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18390917 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17342002 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 28800067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23243212 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 8738724 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12849808 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 28674348 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 21535498 — Biomarker: SDC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SDC1; SDC
Study 17606812 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 2864073 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31391682 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21599820 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18843436 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7942575 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 29200983 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25689594 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30091135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20199265 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 16490430 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16490430 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 16490430 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20808333 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16236854 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16236854 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 14601482 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9925124 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28330794 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 16231754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12228843 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8527710 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8527710 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24284498 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24284498 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10574640 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 10574640 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30590387 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11322052 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 3115445 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30510080 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 30510080 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27849563 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23777763 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 23777763 — Biomarker: ADAMTS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 11726440 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24553365 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22562977 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7841754 — Biomarker: FYN mRNA
Type: Predictive Biomarker (PRD)
Genes: FYN
Study 7841754 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 7841754 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 7841754 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 10757621 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 15665146 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7852539 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2182170 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26712981 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15355745 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15355745 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8033771 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 8033771 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 22014807 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22014807 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19151449 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19151449 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)