AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 16796458 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 16796458 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 12641503 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30780196 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 30780196 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 19733016 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19733016 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 17965037 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 22845695 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 22845695 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22845695 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20627818 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12574564 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24965385 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 18455192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15796146 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10390227 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6647195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26713403 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10493845 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10493845 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6848810 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30885666 — Biomarker: Hypoxia-inducible factor 1-alpha
Type: Predictive Biomarker (PRD)
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 25918718 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 23710686 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 22048172 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17405996 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30795951 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 30795951 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29769107 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26996580 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25219783 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21143094 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9541761 — Biomarker: CALD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CALD1; CAD; CDM
Study 31834381 — Biomarker: CHRNA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA5; NACHRA5
Study 28610969 — Biomarker: CHIC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHIC2; BTL
Study 12850465 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12850465 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12850465 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 21332626 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 8086986 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 18803492 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10922313 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 28619235 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 17493777 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23152480 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16823725 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 16823725 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14638924 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10904025 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10904025 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3030387 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3030387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31731111 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 25164452 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20616365 — Biomarker: CNBP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNBP; RNF163; ZNF9
Study 15516352 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10596996 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 7023861 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15336297 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 10601133 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 10601133 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26849684 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22081557 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22081557 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22081557 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20846424 — Biomarker: ARNT mRNA
Type: Predictive Biomarker (PRD)
Genes: ARNT; BHLHE2
Study 9500565 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 30806017 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31999376 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study 28182503 — Biomarker: Lysosomal acid glucosylceramidase
Type: Pharmacodynamic Biomarker (PDY)
Genes: GBA1; GBA; GC; GLUC
Study 21085591 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27185843 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 27185843 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 20178877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6408016 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 25396263 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17545705 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 25217464 — Biomarker: DMA mRNA
Type: Predictive Biomarker (PRD)
Genes: DMA; HLA-DMA; hCG_2001572
Study 25217464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20018274 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 12226034 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10326889 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 7095559 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 26255546 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17321928 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28539539 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16507585 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 16507585 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15640628 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15640628 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8996289 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 3545130 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 20540447 — Biomarker: PITRM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PITRM1; KIAA1104; MP1; PREP
Study 9974425 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 7572684 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19776178 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15343013 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 11181984 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11181984 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 11181984 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 11181984 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11181984 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31982328 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 31336766 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 31336766 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 26655885 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 26655885 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 21435220 — Biomarker: Survival motor neuron protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 21435220 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 18533896 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31512140 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31512140 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17192355 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 29079603 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26138419 — Biomarker: miR-21-5p
Type: Predictive Biomarker (PRD)
Genes: MIR21
Study 26138419 — Biomarker: miR-21
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR21
Study 11226106 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27581505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22964475 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 18073061 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10603440 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 8682011 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 19723905 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 12477321 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9401833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16632411 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16632411 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10811665 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10811665 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30766716 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20215520 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20215520 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20215520 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20215520 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 10372727 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 25885521 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23539083 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10090295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30643228 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 27592635 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 24699237 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15352909 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10204127 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 7774110 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 7437777 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 7437777 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7437777 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21150933 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17936154 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15378139 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7808646 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22749178 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22749178 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22749178 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22749178 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22749178 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29563108 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 29563108 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 14684561 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 12663595 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25210019 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23471702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20090396 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 11354573 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9112303 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9176830 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9176830 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 9176830 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1412606 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30861510 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26972955 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26972955 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22490761 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 22490761 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22490761 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22490761 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20942575 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20942575 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26164807 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24173773 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 18174269 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 18174269 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17023703 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14681839 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12077738 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9449404 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2374275 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2374275 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20001867 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31126258 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28506281 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 24038152 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16629791 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 25011647 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 25011647 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25011647 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22138360 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 22138360 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17335309 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27103607 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20047363 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 1320846 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31606362 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28030534 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 28030534 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 28030534 — Biomarker: ABCG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 28030534 — Biomarker: SLCO1B3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 28030534 — Biomarker: MRP2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ABCC2; DJS; cMRP
Study 9287227 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8420235 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8420235 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24768239 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24768239 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22476230 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19235080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2337035 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 15314546 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9329410 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 30043885 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 19597412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31033190 — Biomarker: FGD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGD5; ZFYVE23
Study 31033190 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22892323 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 22892323 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17673615 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31665935 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 20715737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12537186 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 30589829 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 23567348 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3049953 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25604722 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25604722 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20577017 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 7091770 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30082141 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study 25591969 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8436095 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31884740 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)