AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 26797700 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17923463 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17923463 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 12127609 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 7552926 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31461355 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 26467096 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 11137102 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11137102 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9853084 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8061852 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3243924 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27022799 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18809622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12892455 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10230189 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1991366 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 29687335 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 22278094 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 15060773 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 9696456 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 7656919 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 15041394 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 30242918 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27873502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27873502 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16952155 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 9416883 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18787222 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 15116008 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 15116008 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15116008 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15116008 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27714002 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16376202 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 12555509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9430987 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9430987 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 9430987 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 8007703 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 18419948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9506266 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8352874 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 12871780 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10329064 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1929608 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1929608 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 1929608 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 6753893 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30093398 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 30093398 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 28378369 — Biomarker: REEP5 mRNA
Type: Predictive Biomarker (PRD)
Genes: REEP5; C5orf18; DP1; TB2
Study 17720383 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17720383 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17720383 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3291150 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25681277 — Biomarker: CXCR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR2; IL8RB
Study 10784627 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 10784627 — Biomarker: ERCC8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC8; CKN1; CSA
Study 10784627 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16583964 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29708829 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 24530176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20591807 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20591807 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20591807 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16618841 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17999333 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17999333 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 17999333 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 7887118 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 7887118 — Biomarker: ANTXR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANTXR1; ATR; TEM8
Study 31506292 — Biomarker: MAP3K5 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP3K5; ASK1; MAPKKK5; MEKK5
Study 16235834 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 1977371 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 28244495 — Biomarker: Sodium/hydrogen exchanger 3
Type: Safety Biomarker (SAF)
Genes: SLC9A3; NHE3
Study 21871113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19720797 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7817832 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14985565 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 14755377 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14755377 — Biomarker: IL16
Type: Safety Biomarker (SAF)
Genes: LCF; IL-16; prIL-16; HsT19289; FLJ42735; FLJ16806
Study 19843490 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 31498885 — Biomarker: CTPS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CTPS1; CTPS
Study 28528342 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 23220477 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23220477 — Biomarker: FOXO3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXO3; FKHRL1; FOXO3A
Study 23220477 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 25090744 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11289484 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 11289484 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9398709 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9398709 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24957485 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 15073842 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 11842947 — Biomarker: MRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MRAS; RRAS3
Study 11842947 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8094308 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30139501 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24250451 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18398809 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 18398809 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18398809 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30301241 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 2580156 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16042796 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 16042796 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10081632 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7574046 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 7574046 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 27628045 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19264972 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15154938 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15154938 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18668535 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 18668535 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 18668535 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26115560 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26115560 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26115560 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26115560 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 15505128 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15505128 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9924223 — Biomarker: SNAP25 mRNA
Type: Predictive Biomarker (PRD)
Genes: SNAP25; SNAP
Study 22776014 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 20057364 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 15867184 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15867184 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30899947 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30899947 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20354448 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 20354448 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 20354448 — Biomarker: ADGRE5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADGRE5; CD97
Study 20354448 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20354448 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 17452762 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15494721 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 31356678 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 31356678 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 31451521 — Biomarker: ABCC6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC6; ARA; MRP6
Study 31198076 — Biomarker: CXADR mRNA
Type: Predictive Biomarker (PRD)
Genes: CXADR; CAR
Study 21386036 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21386036 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21386036 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18535196 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9074572 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9074572 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3532694 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16378639 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 23436922 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 23436922 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16381626 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 7555502 — Biomarker: NR3C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR3C2; MCR; MLR
Study 6158861 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9412655 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 3690230 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26121878 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 26121878 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12534148 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 6120346 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31957521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26219281 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 11350400 — Biomarker: P2RX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: P2RX1; P2X1
Study 11350400 — Biomarker: P2RX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: P2RX2; P2X2
Study 11350400 — Biomarker: P2RX5 mRNA
Type: Predictive Biomarker (PRD)
Genes: P2RX5; P2X5
Study 11350400 — Biomarker: P2RX6 mRNA
Type: Predictive Biomarker (PRD)
Genes: P2RX6; P2RXL1; P2X6
Study 28921839 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 19717156 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18400702 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 31935118 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31935118 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31935118 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 16891570 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 9856370 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23776118 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 10534145 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6983207 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 6983207 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 6983207 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 26999688 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 26999688 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25128278 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 18711762 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30224383 — Biomarker: Beta-secretase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: BACE1; BACE; KIAA1149
Study 30224383 — Biomarker: Amyloid beta peptide (1-40)
Type: Pharmacodynamic Biomarker (PDY)
Genes: APP; A4; AD1
Study 21223653 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 331137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30587857 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17033909 — Biomarker: FANCE mRNA
Type: Predictive Biomarker (PRD)
Genes: FANCE; FACE
Study 11999665 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11999665 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 27473843 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 28641369 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28641369 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 16173527 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29915123 — Biomarker: ABCD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCD2; ALD1; ALDL1; ALDR; ALDRP
Study 25083241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10468065 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1282585 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22921641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18585494 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7609511 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2884879 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 2884879 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 26947331 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26947331 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 26947331 — Biomarker: CDK6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK6; CDKN6
Study 26947331 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 26947331 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 25194408 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 25194408 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8610379 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 8240460 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 24434128 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2167727 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 381955 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 381955 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21964530 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 21964530 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21964530 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26644265 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26644265 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 26644265 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26644265 — Biomarker: IL7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL7
Study 18476293 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16571140 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1308919 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31411985 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 26392403 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 12402450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10465182 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 373393 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31042551 — Biomarker: ADRB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB1; ADRB1R; B1AR
Study 23535872 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 9776437 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1