AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT02634333 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02634333 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT02037477 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT04394377 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT01049451 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT02686177 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study NCT02686177 — Biomarker: Angiopoietin-related protein 4
Type: Predictive Biomarker (PRD)
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study NCT00449618 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04341714 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT03181607 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT03624101 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study NCT00703417 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT04517097 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT01478490 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study NCT01215487 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT01215487 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT01215487 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT01660386 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT00412412 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01071655 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study NCT01071655 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study NCT00733876 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT00957268 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT03951298 — Biomarker: WFS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WFS1
Study NCT02086877 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study NCT01219907 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04419298 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study NCT01390727 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01344902 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study NCT01890798 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study NCT02105116 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT01482689 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study NCT01482689 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study NCT00821340 — Biomarker: RPE65 mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE65
Study NCT03762031 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study NCT01003899 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01125046 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01815749 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT01815749 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study NCT01815749 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00002950 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT03603665 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT03162224 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study NCT03162224 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02619903 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study NCT03905655 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT04461899 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT02423512 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02238262 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01780038 — Biomarker: CHRNA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA3; NACHRA3
Study NCT04160546 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT04160546 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT03235401 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT01279928 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00340587 — Biomarker: ZP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZP2; ZPA
Study NCT00340587 — Biomarker: ZP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZP3; ZP3A; ZP3B; ZPC
Study NCT03981705 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05520853 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05520853 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT05520853 — Biomarker: ROS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROS1; MCF3; ROS
Study NCT02760095 — Biomarker: EED mRNA
Type: Predictive Biomarker (PRD)
Genes: EED
Study NCT02964533 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT03950271 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01082692 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT01416402 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study NCT03736122 — Biomarker: BSG mRNA
Type: Predictive Biomarker (PRD)
Genes: BSG; UNQ6505/PRO21383
Study NCT01365481 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02086240 — Biomarker: TSPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPO; BZRP; MBR
Study NCT04067726 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study NCT03007030 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study NCT03727555 — Biomarker: ABCD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCD1; ALD
Study NCT04140500 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04140500 — Biomarker: LAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAG3; FDC
Study NCT00672464 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00821886 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00821886 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT01986764 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT01986764 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study NCT02734953 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study NCT02734953 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study NCT02546921 — Biomarker: Folate receptor alpha
Type: Predictive Biomarker (PRD)
Genes: FOLR1; FOLR
Study NCT01167491 — Biomarker: TYROBP mRNA
Type: Predictive Biomarker (PRD)
Genes: TYROBP; DAP12; KARAP
Study NCT02186600 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01504477 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01504477 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT00644670 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04281602 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT04281602 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01515059 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT01515059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00222872 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03058575 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03058575 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00529399 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study NCT03236701 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01022112 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT03453268 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01743989 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT01743989 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT01741103 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT01737580 — Biomarker: TLR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR7; UNQ248/PRO285
Study NCT02053818 — Biomarker: TNNT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNNT1; TNT
Study NCT03117816 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT03117816 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT00867165 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT00867165 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00867165 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01805752 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT02483780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03703167 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study NCT00617344 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT04637269 — Biomarker: TNFRSF17 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF17; BCM; BCMA
Study NCT01370590 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01029223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01373528 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT01373528 — Biomarker: Urine free cortisol
Type: Surrogate Endpoint (SUR)
Study NCT04440566 — Biomarker: OGT mRNA
Type: Predictive Biomarker (PRD)
Genes: OGT
Study NCT03302260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02118727 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study NCT02693002 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study NCT02906163 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02048228 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT00072267 — Biomarker: UCN mRNA
Type: Predictive Biomarker (PRD)
Genes: UCN
Study NCT03632941 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01274091 — Biomarker: PPARG mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARG; NR1C3
Study NCT00941330 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT00455065 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03429803 — Biomarker: RAF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAF1; RAF
Study NCT03637218 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT04506645 — Biomarker: NPR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NPR1; ANPRA
Study NCT04506645 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT04506645 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01891175 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04717453 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study NCT01832558 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT01832558 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study NCT02819752 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03950752 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study NCT00350597 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00254826 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT02627703 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT03073252 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00430703 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study NCT03236584 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT05215964 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT05215964 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study NCT03203330 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT00565773 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT04001634 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03391934 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03391934 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT02032082 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02032082 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study NCT03165747 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02781675 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02781675 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT02999074 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study NCT02669459 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study NCT04505410 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00485277 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01488526 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT03930693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01522716 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT01512758 — Biomarker: Aurora kinase A
Type: Predictive Biomarker (PRD)
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT03270540 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03015168 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study NCT03154385 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study NCT02932540 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02184975 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study NCT04074668 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT02277184 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT02277184 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study NCT03500991 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03612778 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04470635 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT02426840 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00010010 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT04218032 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02234791 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study NCT01683539 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT01683539 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT04463420 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT04243707 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT04579471 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT02876445 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study NCT02551653 — Biomarker: PTK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTK2; FAK; FAK1
Study NCT04324723 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00111267 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT04076592 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT04076592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05021016 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT03955913 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02497443 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT02341742 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02334475 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT02334475 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT01962532 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04863391 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT01645215 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT01955642 — Biomarker: PGP mRNA
Type: Predictive Biomarker (PRD)
Genes: PGP
Study NCT03169335 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study NCT04469972 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00602043 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study NCT00602043 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT02209688 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT02209688 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study NCT02815007 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00972309 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT01416974 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT01661764 — Biomarker: FADS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS1; FADSD5
Study NCT01661764 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02758275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02570919 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study NCT03697551 — Biomarker: SSTR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SSTR2
Study NCT02605551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00216112 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study NCT00216112 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT03581903 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT01565278 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study NCT01223352 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT03162198 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study NCT05595252 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study NCT02401165 — Biomarker: PPP1R15A mRNA
Type: Predictive Biomarker (PRD)
Genes: PPP1R15A; GADD34
Study NCT00819143 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT00819143 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT00819143 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT02773004 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT01016665 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study NCT04042701 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04042701 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF