AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 16055868 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8006330 — Biomarker: ABL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABL2; ABLL; ARG
Study 1101909 — Biomarker: EDAR mRNA
Type: Predictive Biomarker (PRD)
Genes: EDAR; DL
Study 23668772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14627528 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 7489421 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18295467 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 18295467 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17201084 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30497484 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 21793327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10973651 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31321951 — Biomarker: F7 mRNA
Type: Predictive Biomarker (PRD)
Genes: F7
Study 31321951 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 10370741 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 7526483 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 28573374 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 28573374 — Biomarker: TRPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPA1; ANKTM1
Study 25912697 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10979055 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10979055 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1397666 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18047870 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 31931977 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25117817 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22300946 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 22300946 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 2097777 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2097777 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31196453 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 31196453 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31196453 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25663767 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 25663767 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 19494217 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19494217 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 15121733 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11436644 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31558480 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 31558480 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27459375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23753094 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 18543304 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15718847 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24472402 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 22820409 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19563331 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 9891541 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 15068851 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15068851 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9699891 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 7916278 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 31932513 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31932513 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 26550817 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15023883 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15023883 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8390508 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24660827 — Biomarker: BAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAK1; BAK; BCL2L7; CDN1
Study 22726593 — Biomarker: TLR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR7; UNQ248/PRO285
Study 22726593 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 20147603 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18305126 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 18305126 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 18305126 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 14738561 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17215186 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9306087 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 30033064 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30033064 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27813617 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 18922386 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 18922386 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10363425 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9331518 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19006027 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8592096 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8592096 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6362341 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22799482 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22799482 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14623837 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 27075863 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27075863 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25312202 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 22460469 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19676097 — Biomarker: FKBP5 mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: FKBP5; AIG6; FKBP51
Study 11320545 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 8203337 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8203337 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3555588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25799402 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15763649 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15763649 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 21291323 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21291323 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7890436 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 3371085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28777242 — Biomarker: NR1I2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1I2; PXR
Study 28777242 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 28777242 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 26033349 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21744191 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16778714 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 11781651 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21733061 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 1607582 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 21641362 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21641362 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11224578 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9143000 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 8204806 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 18467909 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 11753266 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 29562041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19293667 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19293667 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19293667 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17108825 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17976228 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17976228 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28857839 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 1442760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30587335 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 229146 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 28706955 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 23984352 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 20189663 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16505423 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 14764220 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27504605 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27504605 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27504605 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25310116 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10077358 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 25429550 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 23328954 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 23328954 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 15001463 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 3049266 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 12172218 — Biomarker: GNB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNB3
Study 12172218 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 18343247 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15969882 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 27658693 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22589472 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 20697801 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20697801 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 17663731 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2181991 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 16710614 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8420065 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8420065 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27678439 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30882596 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23298824 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20734049 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 17142138 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17142138 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17142138 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8287662 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30747566 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 25488849 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 14569096 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 14569096 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14569096 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 10777036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31070471 — Biomarker: PLA2G2A mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G2A; PLA2B; PLA2L; RASF-A
Study 23958407 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23958407 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 21752880 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21752880 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21752880 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19635616 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22707560 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8568002 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27010144 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27010144 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20199985 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12028504 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16777318 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 16777318 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 16777318 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11985406 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31702469 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 24500238 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12140629 — Biomarker: GDA mRNA
Type: Predictive Biomarker (PRD)
Genes: GDA; KIAA1258
Study 2649197 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 20687931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1837713 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6354904 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 28070602 — Biomarker: PCSK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK5; PC5; PC6
Study 27115567 — Biomarker: BTC mRNA
Type: Predictive Biomarker (PRD)
Genes: BTC
Study 15867044 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 30025007 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 30025007 — Biomarker: ODAM mRNA
Type: Predictive Biomarker (PRD)
Genes: ODAM; APIN
Study 30025007 — Biomarker: FDCSP mRNA
Type: Predictive Biomarker (PRD)
Genes: FDCSP; C4orf7; UNQ733/PRO1419
Study 24045403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9209645 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 9209645 — Biomarker: EEF1E1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EEF1E1; AIMP3; P18
Study 9209645 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 3689626 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20388917 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20388917 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 20388917 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24418164 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 21701811 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21701811 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16019355 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16019355 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23860695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18327066 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21537858 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 18264697 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 31241173 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 31241173 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 18019665 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study 18019665 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 15668481 — Biomarker: CCND1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND1; BCL1; PRAD1
Study 15668481 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 10770450 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 8681493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1920817 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25491391 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 7608809 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 2122713 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22222299 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 7934188 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28117141 — Biomarker: UCHL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCHL1
Study 28117141 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 25967848 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 25967848 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25967848 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25967848 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25967848 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11247890 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8314169 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30252723 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 30252723 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 20507378 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 20507378 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 12356338 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31056705 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 18343264 — Biomarker: SV2A mRNA
Type: Predictive Biomarker (PRD)
Genes: SV2A; KIAA0736; PSEC0174
Study 8916480 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1