AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT03372447 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT02887365 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study NCT02217683 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study NCT02944734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04119388 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT04623255 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04776889 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04776889 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study NCT04776889 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03889990 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT01924195 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study NCT01924195 — Biomarker: FLT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT4; VEGFR3
Study NCT03906201 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01556789 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study NCT01307410 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00850928 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study NCT00357786 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study NCT03285204 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study NCT00831857 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT04134377 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03726541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01193049 — Biomarker: Th2 cell
Type: Safety Biomarker (SAF)
Study NCT01193049 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study NCT01193049 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study NCT03535090 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study NCT04146402 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study NCT02092324 — Biomarker: CSF3R mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3R; GCSFR
Study NCT01945788 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01372813 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01372813 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study NCT01372813 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT01372813 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT02451254 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study NCT02451254 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT00616772 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00398138 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01131429 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04506281 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02061904 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT02005510 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study NCT01413828 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00669513 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00068484 — Biomarker: DNA topoisomerase I
Type: Pharmacodynamic Biomarker (PDY)
Genes: TOP1
Study NCT02428075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03136003 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study NCT03315858 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT03315858 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT03315858 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT01581996 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT00671970 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00671970 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study NCT00671970 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00671970 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study NCT00671970 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00671970 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT04489940 — Biomarker: HMGA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: HMGA2; HMGIC
Study NCT05514925 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01226472 — Biomarker: CCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR4; CMKBR4
Study NCT03199131 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT04567953 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT01547806 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT01547806 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01379560 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT03193944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04131205 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study NCT04173403 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study NCT04173403 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00767299 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01810822 — Biomarker: CYBB mRNA
Type: Predictive Biomarker (PRD)
Genes: CYBB; NOX2
Study NCT01810822 — Biomarker: GPX4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPX4
Study NCT00748332 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01392235 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study NCT01392235 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01392235 — Biomarker: FLT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT4; VEGFR3
Study NCT02161523 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02161523 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02161523 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT02161523 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study NCT00133185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02120469 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03030391 — Biomarker: PDE4B mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE4B; DPDE4
Study NCT02741310 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00171002 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02438761 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study NCT00012207 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT01394211 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT00856817 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study NCT03011775 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study NCT03011775 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01723085 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT03650049 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT03850171 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study NCT01615692 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study NCT02559180 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02559180 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT02038725 — Biomarker: ABCD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCD2; ALD1; ALDL1; ALDR; ALDRP
Study NCT02038725 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03634293 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study NCT00653068 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01305941 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01305941 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00030160 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01428986 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01322529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00020449 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study NCT02779530 — Biomarker: CYP4F2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP4F2
Study NCT01061840 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT02774668 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study NCT04461704 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03050892 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study NCT02089867 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01140165 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02816060 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study NCT02233322 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT00981929 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study NCT00981929 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT00981929 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study NCT00981929 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study NCT00981929 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT02654457 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study NCT02067455 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02766010 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT02766010 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03630523 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study NCT03375697 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04813289 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02283333 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study NCT02792036 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study NCT03399786 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00096551 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT03389451 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01637857 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study NCT02037204 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT01844570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03597542 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03597542 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03597542 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT03011554 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT03373500 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01372202 — Biomarker: CHFR mRNA
Type: Predictive Biomarker (PRD)
Genes: CHFR; RNF196
Study NCT00019136 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT04456049 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT01855997 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT03694067 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study NCT00943410 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04364022 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT00040521 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study NCT03866434 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study NCT03066310 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study NCT04171167 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study NCT00054756 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study NCT00449488 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study NCT04601181 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study NCT03761134 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00718250 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study NCT02756546 — Biomarker: miR-181a
Type: Safety Biomarker (SAF)
Study NCT02756546 — Biomarker: miR-21
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR21
Study NCT00527514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03582436 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study NCT04585568 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01599819 — Biomarker: BAX mRNA
Type: Predictive Biomarker (PRD)
Genes: BAX; BCL2L4
Study NCT00746473 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00746473 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT05305001 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT05305001 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study NCT05305001 — Biomarker: CDKN2A mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2A; CDKN2; MTS1
Study NCT05305001 — Biomarker: Serine/threonine-protein kinase STK11
Type: Safety Biomarker (SAF)
Genes: STK11
Study NCT05305001 — Biomarker: MLH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MLH1; COCA2
Study NCT05305001 — Biomarker: DNA mismatch repair protein MSH2
Type: Predictive Biomarker (PRD)
Genes: MSH2
Study NCT05305001 — Biomarker: PALB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PALB2; FANCN
Study NCT03530761 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study NCT01799161 — Biomarker: KLRK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRK1; D12S2489E; NKG2D
Study NCT04024449 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT01136460 — Biomarker: CYP1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1B1
Study NCT01136460 — Biomarker: MYOC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYOC; GLC1A; TIGR
Study NCT02733146 — Biomarker: Plasma DNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT04106180 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT03633513 — Biomarker: Leucine-rich repeat kinase 2
Type: Pharmacodynamic Biomarker (PDY)
Genes: LRRK2; PARK8
Study NCT03633513 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study NCT03633513 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT03633513 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02149173 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study NCT02149173 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT03744598 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT00252317 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT03418220 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT01237223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01070706 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04329559 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT01366534 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study NCT01366534 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT02027272 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06486870 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT03645915 — Biomarker: SLC2A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A1; GLUT1
Study NCT03645915 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study NCT01140776 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study NCT00045357 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT01023373 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT01023373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00654823 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study NCT00654823 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study NCT00725829 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01764022 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02740894 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT06446895 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT06446895 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT06446895 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03634228 — Biomarker: MDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM2
Study NCT00659906 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00553618 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT00797810 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT00952770 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT06279780 — Biomarker: MFN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFN1
Study NCT06279780 — Biomarker: FIS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FIS1; TTC11; CGI-135
Study NCT06279780 — Biomarker: DNM1L mRNA
Type: Predictive Biomarker (PRD)
Genes: DNM1L; DLP1; DRP1
Study NCT06279780 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT06279780 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT06279780 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT06279780 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT06279780 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT06279780 — Biomarker: Mitochondrial membrane potential
Type: Pharmacodynamic Biomarker (PDY)
Study NCT06279780 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study NCT06279780 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study NCT06279780 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study NCT05016440 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)