AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23479592 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14608833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12080805 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24296869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12948416 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14520725 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 14520725 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 1389240 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 17302256 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 3903735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12068339 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9247454 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 30776777 — Biomarker: SIGLEC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIGLEC1; SN
Study 30776777 — Biomarker: SLC40A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC40A1; FPN; FPN1; IREG1; SLC11A3; MSTP079
Study 29256407 — Biomarker: TRPM6 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPM6; CHAK2
Study 29256407 — Biomarker: SLC41A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC41A1
Study 17251278 — Biomarker: SLC2A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A5; GLUT5
Study 17251278 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 17251278 — Biomarker: SLC2A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A1; GLUT1
Study 17251278 — Biomarker: SLC2A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A3; GLUT3
Study 17251278 — Biomarker: SLC2A8 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A8; GLUT8; GLUTX1
Study 17251278 — Biomarker: SLC2A12 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A12; GLUT12
Study 27562916 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 28867538 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 26511807 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 15177526 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8033618 — Biomarker: Tropomyosin-related kinase A
Type: Pharmacodynamic Biomarker (PDY)
Genes: NTRK1; MTC; TRK; TRKA
Study 31814153 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 21173171 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17319365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9578193 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 2651251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 319871 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22331686 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22331686 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10937568 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9295846 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 3470498 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 30518633 — Biomarker: Tumor-infiltrating lymphocyte
Type: Predictive Biomarker (PRD)
Study 16088097 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7869919 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 7869919 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26168857 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14751370 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 9593041 — Biomarker: DHFR
Type: Safety Biomarker (SAF)
Genes: DHFR1
Study 3257532 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30320542 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25783161 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16391331 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12673681 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 1346807 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 15766294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9156785 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9156785 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9156785 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 9156785 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 9885797 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 27452327 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27452327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17710290 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 18216764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16521223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11101061 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11101061 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 29373334 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31118095 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31118095 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 31118095 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 10720591 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26109202 — Biomarker: TRIL mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIL; KIAA0644
Study 19502017 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18284462 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18284462 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15918446 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 15918446 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 15918446 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12095495 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 12095495 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 7985893 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2974416 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 18317189 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 20938039 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 7607751 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7607751 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7607751 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20523301 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 31165854 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31165854 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 12119210 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 9710040 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 7480965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7480965 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 2470569 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25111121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22981146 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9625823 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 23986090 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 20659263 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 6319633 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28944645 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31131743 — Biomarker: FMOD mRNA
Type: Predictive Biomarker (PRD)
Genes: FMOD; FM; SLRR2E
Study 19741042 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 1723773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27737436 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 1337337 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15634808 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24495355 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 9834924 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9834924 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30590973 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 15670536 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7589641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7589641 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7589641 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 17724493 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 10049414 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 10049414 — Biomarker: Serum alkaline phosphatase and bilirubin
Type: Surrogate Endpoint (SUR)
Study 14678954 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 11434175 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9070128 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 8508727 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11027812 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 6488684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30570525 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1898743 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 16253595 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12384411 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23128822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19104723 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16144890 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 6352272 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24830937 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29493562 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7623907 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7128668 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20609467 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 20609467 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 902232 — Biomarker: MERTK mRNA
Type: Predictive Biomarker (PRD)
Genes: MERTK; MER
Study 15380456 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 15380456 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 10734016 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 3926511 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 30700364 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 11361052 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31533069 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 31533069 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18772216 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8675164 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8675164 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8675164 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 8675164 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 1676306 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26677770 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 2138049 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 106432 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27255243 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 25238912 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11774098 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10610077 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 10610077 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 619949 — Biomarker: EMB mRNA
Type: Predictive Biomarker (PRD)
Genes: EMB
Study 1599353 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24096258 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28060545 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11920457 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 9280994 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1587065 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27328023 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 25537204 — Biomarker: RPE65 mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE65
Study 22546535 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19566584 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15809508 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 15809508 — Biomarker: Serum phosphate
Type: Surrogate Endpoint (SUR)
Study 11808976 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 6999618 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 21394639 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 11589932 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11589932 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9751239 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7942122 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 23302902 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 12600846 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 10962425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27166360 — Biomarker: MEF2B mRNA
Type: Predictive Biomarker (PRD)
Genes: MEF2B; XMEF2
Study 27166360 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 8619521 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26891418 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 19174497 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 9587048 — Biomarker: EPHA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPHA3; ETK; ETK1; HEK; TYRO4
Study 8017465 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25636814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11387994 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 21438929 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 20335115 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11380317 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 2851179 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23123199 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 23123199 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23123199 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 23123199 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25452309 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24506950 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 24958250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20539854 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15732857 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30638840 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22136024 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 30548118 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30548118 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30548118 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29798118 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 16809572 — Biomarker: TNF-related weak inducer of apoptosis
Type: Predictive Biomarker (PRD)
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study 16809572 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16809572 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 2887542 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2887542 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18471252 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16509867 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 9172131 — Biomarker: CCDC88A mRNA
Type: Predictive Biomarker (PRD)
Genes: CCDC88A; APE; GRDN; KIAA1212
Study 9172131 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 22562609 — Biomarker: CBR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CBR1; CBR; CRN; SDR21C1
Study 22562609 — Biomarker: CBR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CBR3; SDR21C2
Study 2756353 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31359814 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31138020 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11220085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29194749 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23337343 — Biomarker: CNR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNR1; CNR
Study 23337343 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16773618 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 8882695 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 23155019 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 31272326 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28029656 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28029656 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 28029656 — Biomarker: Platelet to lymphocyte
Type: Safety Biomarker (SAF)
Study 25631875 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22523532 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9923412 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 8072258 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31194213 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 21576655 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19260129 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 17101806 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15456520 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8773158 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1281103 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 14640990 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17425871 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 12627416 — Biomarker: USH1G mRNA
Type: Predictive Biomarker (PRD)
Genes: USH1G; SANS