AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31512330 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 21735653 — Biomarker: PLXNB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLXNB1; KIAA0407; PLXN5; SEP
Study 21735653 — Biomarker: SEPTIN6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEPTIN6; KIAA0128; SEP2; SEPT6
Study 19164187 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7018363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7018363 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 10076939 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19755697 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19755697 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9881389 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9881389 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1103213 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23821088 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20975012 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12230618 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 21038648 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31671276 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25871304 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23698211 — Biomarker: DSTN mRNA
Type: Predictive Biomarker (PRD)
Genes: DSTN; ACTDP; DSN
Study 11360574 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 11360574 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 24481828 — Biomarker: MAVS mRNA
Type: Predictive Biomarker (PRD)
Genes: MAVS; IPS1; KIAA1271; VISA
Study 18974704 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18974704 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 18974704 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18974704 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 16568436 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 28933625 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 9862513 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23148500 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 23148500 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21191380 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 16984797 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 9750603 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28701596 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24995901 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 24995901 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 24995901 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 11730260 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26043561 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 26043561 — Biomarker: MALT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MALT1; MLT
Study 19031076 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19031076 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 15327407 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15327407 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7981758 — Biomarker: TNFRSF10A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 30185733 — Biomarker: Survival motor neuron protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 18549459 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 28687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24583931 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22483479 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 7033578 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31631602 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 15866684 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15866684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15866684 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 15866684 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 10221663 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 10221663 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7759461 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 7759461 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11464260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11416702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27464593 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27464593 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22463698 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 28012682 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 25830924 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 25830924 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 8124836 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2531605 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30261963 — Biomarker: FBN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBN1; FBN
Study 17229229 — Biomarker: GK mRNA
Type: Predictive Biomarker (PRD)
Genes: GK
Study 11665964 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 11665964 — Biomarker: TNFRSF10A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 9680497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22981045 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8985844 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20423913 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 16257026 — Biomarker: DHFR
Type: Safety Biomarker (SAF)
Genes: DHFR1
Study 11745931 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9267858 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 3499066 — Biomarker: PDXP mRNA
Type: Predictive Biomarker (PRD)
Genes: PDXP; CIN; PLP; PLPP
Study 27600061 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 21190597 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21190597 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 21190597 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16985020 — Biomarker: MTRR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTRR
Study 16985020 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 16985020 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 29693605 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27208375 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 27208375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19129749 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 17496672 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7989704 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10813483 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 8986916 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8986916 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31054568 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26778006 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 26778006 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 20103448 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20103448 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20103448 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20103448 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20103448 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20103448 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16123721 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12100762 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29040012 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 23828112 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 21138617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21138617 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 21138617 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30244671 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 27729174 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 10500056 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10500056 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21052021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3254831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18091023 — Biomarker: PPARG mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARG; NR1C3
Study 10752681 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29678619 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22110163 — Biomarker: APC
Type: Safety Biomarker (SAF)
Genes: DP2; DP3; DP2.5; PPP1R46
Study 22110163 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 17846979 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study 17846979 — Biomarker: Urine free cortisol
Type: Surrogate Endpoint (SUR)
Study 17846979 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9678314 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 28595341 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28595341 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28595341 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29557709 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 29557709 — Biomarker: ABCG2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 29557709 — Biomarker: ABCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 20091057 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 4553613 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25622774 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 21351829 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 21351829 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 16995861 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15560538 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9285655 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19204263 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 16432273 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 9432291 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29777823 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 22537617 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22537617 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29604402 — Biomarker: HSPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPB1; HSP27; HSP28
Study 6664741 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 7158232 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26915841 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2976110 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 2976110 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31822212 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28279368 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12955293 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 10832598 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 3302150 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31860981 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31860981 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27799236 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19485818 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19485818 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19485818 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 28530142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28530142 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18492840 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 1293305 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21532737 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 9495662 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9495662 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22552359 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 16924568 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9075036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23748185 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16483391 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 9139168 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 9139168 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8440356 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 20466223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10232312 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22938716 — Biomarker: CAMP mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMP; CAP18; FALL39; HSD26
Study 31658134 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31658134 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 28062625 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 28062625 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 28062625 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26440235 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15906019 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 12270852 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 12270852 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 12270852 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 12270852 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 24373251 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 2884454 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31707498 — Biomarker: RGS4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RGS4
Study 16935049 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 10849375 — Biomarker: Hypoxanthine-guanine phosphoribosyltransferase
Type: Safety Biomarker (SAF)
Genes: HPRT1; HPRT
Study 19694216 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19694216 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23096251 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11294048 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11294048 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7688008 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31608373 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29055711 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9357931 — Biomarker: SERPINA7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA7; TBG
Study 8403788 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 6325525 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 30877742 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 29176386 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 24671918 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 18498922 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 15711315 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12742294 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8638527 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27448700 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17283260 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2184874 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 23827078 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 23827078 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23827078 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11737382 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9764979 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 30058418 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30058418 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 27401361 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 9377616 — Biomarker: Connecting peptide
Type: Safety Biomarker (SAF)
Genes: AHSG; FETUA; PRO2743
Study 2455121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11199329 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11199329 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 11199329 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17019663 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1389517 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2412041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31433785 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 29906251 — Biomarker: SLFN11 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLFN11