AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 9082588 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6094194 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9644282 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 3372718 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8228792 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 8228792 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26450639 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 26450639 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 26450639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15983962 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12853744 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10539816 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8732962 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 1815967 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 19563288 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 11828905 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 31539061 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 21455724 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 9050957 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25963336 — Biomarker: ORMDL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ORMDL3
Study 16188958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8865525 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 8865525 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28604556 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10566652 — Biomarker: UCP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP2; SLC25A8
Study 10566652 — Biomarker: UCP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP3; SLC25A9
Study 10566652 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7676795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2178522 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 20001450 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 16041270 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7725851 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 7725851 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31759909 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25194004 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23514842 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23514842 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15157345 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 30228265 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20921964 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20921964 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20921964 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 18691778 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 16522906 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 9209728 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 29480399 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28331306 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28331306 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 28331306 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18351337 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 7942933 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7942933 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2976727 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 22048987 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 30742245 — Biomarker: PTK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTK2; FAK; FAK1
Study 28459407 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 28459407 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28459407 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20040554 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 11673819 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7986152 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7986152 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7986152 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21945737 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14699020 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11704086 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2218871 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 6157258 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 17571966 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 10404794 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26028346 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 26028346 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26028346 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29782435 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20598488 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 16386942 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1731544 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22474202 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 9377073 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 3853581 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3853581 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18388088 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24814697 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 18173844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3052168 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22005052 — Biomarker: DMTN mRNA
Type: Predictive Biomarker (PRD)
Genes: DMTN; DMT; EPB49
Study 22005052 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11255716 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 30032196 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30032196 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30032196 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 25921382 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 30890109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16215305 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 31660904 — Biomarker: MGP mRNA
Type: Predictive Biomarker (PRD)
Genes: MGP; MGLAP; GIG36
Study 9258265 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28870095 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 9583838 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 9583838 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21518046 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 21518046 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10948073 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22954510 — Biomarker: OPRK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OPRK1; OPRK
Study 22954510 — Biomarker: OPRD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OPRD1; OPRD
Study 18426893 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7955906 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3117236 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19211665 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 19211665 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19211665 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19211665 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3475201 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30561509 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 2169833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24274342 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 31162810 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 31162810 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31162810 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19664895 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 8181200 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 8181200 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23216616 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 21315210 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12727580 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 9367464 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30236824 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12055417 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31640705 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 26959184 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 15616030 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15616030 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12611732 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12611732 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 9650124 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 3378856 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24569031 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 20659185 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 17261891 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9033699 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9033699 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27181277 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10192755 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 30561610 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26103129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20236716 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20236716 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 10923282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8828991 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 8828991 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 1424207 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 4096058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30134289 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24356594 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20308973 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9649976 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11895463 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 2898400 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 31452382 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18729781 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9622147 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24239201 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 28885881 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 21764693 — Biomarker: SLC22A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A4; ETT; OCTN1; UT2H
Study 21764693 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21764693 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 21764693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1389931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14977778 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8095558 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 24142756 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23311404 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 23311404 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 1447501 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10674014 — Biomarker: MALT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MALT1; MLT
Study 30479202 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 17170385 — Biomarker: TAC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAC1; NKA; NKNA; TAC2
Study 10800819 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 10800819 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3967459 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 23478476 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7701032 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7701032 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28562168 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21584681 — Biomarker: Plasma DNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16009798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28735818 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28735818 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25236187 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 675848 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 24145678 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6364906 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 6364906 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31262366 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 27943112 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27943112 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23624802 — Biomarker: ISG15 mRNA
Type: Predictive Biomarker (PRD)
Genes: ISG15; G1P2; UCRP
Study 23624802 — Biomarker: STAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT1
Study 23624802 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 23624802 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 23624802 — Biomarker: SOCS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOCS1; SSI1; TIP3
Study 23624802 — Biomarker: SOCS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOCS3; CIS3; SSI3
Study 23624802 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 21285885 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21285885 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21285885 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 19342599 — Biomarker: Angiopoietin-related protein 4
Type: Predictive Biomarker (PRD)
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 19342599 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21574963 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 21574963 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25447615 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8221449 — Biomarker: DPT mRNA
Type: Predictive Biomarker (PRD)
Genes: DPT
Study 27400912 — Biomarker: ZNF423 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZNF423; KIAA0760; NPHP14; OAZ
Study 27400912 — Biomarker: CTSO mRNA
Type: Predictive Biomarker (PRD)
Genes: CTSO; CTSO1
Study 24938224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12766124 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25378913 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20658791 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 26846607 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 26846607 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 22583135 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16101620 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 11908467 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 21266057 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 21266057 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 21266057 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 14624410 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14624410 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14624410 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14624410 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 12127381 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10447791 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7594703 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 367885 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 367885 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19769721 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30041526 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30041526 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 30041526 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 21907863 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29909907 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20930337 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26898348 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 12370800 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2655606 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)