AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 28777984 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 24078554 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19673614 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19673614 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 16275011 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10619929 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 10619929 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8616766 — Biomarker: CHAD mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAD; SLRR4A
Study 10509552 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7815656 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31761539 — Biomarker: MPV17L2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MPV17L2; FKSG24
Study 31761539 — Biomarker: PIF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PIF1; C15orf20
Study 31761539 — Biomarker: LPIN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LPIN1; KIAA0188
Study 31761539 — Biomarker: DCTN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DCTN3; DCTN22
Study 31761539 — Biomarker: DERA mRNA
Type: Predictive Biomarker (PRD)
Genes: DERA; CGI-26
Study 31761539 — Biomarker: ATP7B mRNA
Type: Predictive Biomarker (PRD)
Genes: ATP7B; PWD; WC1; WND
Study 31761539 — Biomarker: NEK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: NEK5
Study 31761539 — Biomarker: HVCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HVCN1; VSOP; UNQ578/PRO1140
Study 31761539 — Biomarker: MARK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARK2; EMK1
Study 22906808 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30672192 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 10634364 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 2906699 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28641703 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 8862952 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 27228432 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15711037 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 15711037 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 28553094 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19687343 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19687343 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26580234 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16253100 — Biomarker: Major prion protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRNP; ALTPRP; PRIP; PRP
Study 12037693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12037693 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10208561 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 30429410 — Biomarker: ANGPTL8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANGPTL8; C19orf80; RIFL; UNQ599/PRO1185
Study 27893326 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 27893326 — Biomarker: DNA repair endonuclease XPF
Type: Predictive Biomarker (PRD)
Genes: ERCC4; ERCC11; XPF
Study 25778467 — Biomarker: ACSL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACSL1; FACL1; FACL2; LACS; LACS1; LACS2
Study 25778467 — Biomarker: XPO4 mRNA
Type: Predictive Biomarker (PRD)
Genes: XPO4; KIAA1721
Study 25778467 — Biomarker: TAS1R3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAS1R3; T1R3; TR3
Study 25778467 — Biomarker: LCA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: LCA5; C6orf152
Study 25778467 — Biomarker: DNAH5 mRNA
Type: Predictive Biomarker (PRD)
Genes: DNAH5; DNAHC5; HL1; KIAA1603
Study 25778467 — Biomarker: PTPRG mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRG; PTPG
Study 25778467 — Biomarker: MAGI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAGI1; AIP3; BAIAP1; BAP1; TNRC19
Study 25778467 — Biomarker: STRADA mRNA
Type: Predictive Biomarker (PRD)
Genes: STRADA; LYK5; STRAD
Study 25778467 — Biomarker: AKAP12 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKAP12; AKAP250
Study 25778467 — Biomarker: ARFGEF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARFGEF2; ARFGEP2; BIG2
Study 23337018 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 19619442 — Biomarker: ADAM17 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM17; CSVP; TACE
Study 16249701 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12072676 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30208421 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 18633177 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23415779 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 19154960 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 7895895 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 3318450 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25591431 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20722026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18685062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30744529 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 27034176 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 8576661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21458191 — Biomarker: KIF6 mRNA
Type: Predictive Biomarker (PRD)
Genes: KIF6; C6orf102
Study 21458191 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3436153 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 16563324 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23341572 — Biomarker: HSD17B1 mRNA
Type: Safety Biomarker (SAF)
Genes: HSD17B1; E17KSR; EDH17B1; EDH17B2; EDHB17; SDR28C1
Study 23341572 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 23341572 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23341572 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 19302581 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 9814458 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28660719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15126990 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28389125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25657051 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 31626100 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31626100 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26142266 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22989378 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 22989378 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22989378 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20571252 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 8828539 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 24972963 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 9383690 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 2452920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21835294 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16707747 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 14630985 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 9216973 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 9216973 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9216973 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7967419 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 2441167 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25914474 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23881958 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12962775 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7966077 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31185379 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 26621634 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17015784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11035136 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11035136 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11035136 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31600343 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27484880 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 27453302 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 19897678 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 19897678 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7674841 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 21107435 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31684758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20799296 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20799296 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9425911 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 3049116 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 21636116 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 11268375 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 3952172 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20345708 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 18544975 — Biomarker: LEPROT mRNA
Type: Predictive Biomarker (PRD)
Genes: LEPROT; LEPR; OBR
Study 18544975 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8739857 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31711168 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19616166 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17196453 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15272394 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18389332 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18389332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18389332 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18389332 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15358643 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3310529 — Biomarker: REST mRNA
Type: Predictive Biomarker (PRD)
Genes: REST; NRSF; XBR
Study 24300152 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18421460 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 8610922 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28816242 — Biomarker: FMR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMR1
Study 12186794 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9933261 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7748048 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7748048 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24250318 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22566115 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18576354 — Biomarker: CCR2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCR2; CMKBR2
Study 18576354 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 18576354 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 31646981 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 30737098 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 23245705 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14714242 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 2521934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29025830 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 25927504 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19326811 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24621971 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 21149427 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 8911338 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 25695618 — Biomarker: TET2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET2; KIAA1546; Nbla00191
Study 25695618 — Biomarker: CSMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSMD1; KIAA1890; UNQ5952/PRO19863
Study 22051162 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 9809846 — Biomarker: ALPK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALPK1; KIAA1527; LAK
Study 25703086 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 24319685 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24319685 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 24319685 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20965319 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30036596 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26871954 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 7836027 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 29882318 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18394162 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17572317 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11432888 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 17904817 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2856702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30261306 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22546132 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 22546132 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 22546132 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16382061 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 11206587 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 1517788 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24074777 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18174880 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18174880 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2939217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18369631 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 10643842 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23406256 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 21211651 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 8568016 — Biomarker: NTS mRNA
Type: Predictive Biomarker (PRD)
Genes: NTS
Study 30587323 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 12954158 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30346660 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 28886083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16311436 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27993418 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18329818 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 1697373 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1697373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25022108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22949599 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 20058615 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 17584555 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15363008 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 11530028 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23233651 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 10572606 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 30403976 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30403976 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 24690513 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2021151 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2021151 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8397246 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21221681 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 4357222 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17203621 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 25190072 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 21597387 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19812066 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 19812066 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 19812066 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 31996422 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31996422 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 22957727 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 20496728 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 20496728 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17186726 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 17186726 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17186726 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 29270001 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29270001 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25668196 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24667750 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11280344 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 27317162 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27317162 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27317162 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19036981 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 15696567 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1