AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 30857843 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30857843 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28509934 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 12732605 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10924732 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20215781 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20215781 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10720082 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24448692 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21781149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15821394 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17313001 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 6337003 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18173139 — Biomarker: LIF mRNA
Type: Predictive Biomarker (PRD)
Genes: LIF; HILDA
Study 28222178 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 28222178 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22867975 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22867975 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22867975 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 21193172 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 12446059 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12446059 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10473840 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 31377226 — Biomarker: AQP5 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP5
Study 30390409 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22906006 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12584670 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12584670 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 12584670 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12584670 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14514397 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 29572795 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 16717300 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 3994010 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19414572 — Biomarker: DHFR
Type: Safety Biomarker (SAF)
Genes: DHFR1
Study 9520826 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 9520826 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 30451582 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 16686906 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 15490785 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31371114 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20484128 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 18713923 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16477766 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31612909 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 26011779 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23230975 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16490891 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16490891 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10613410 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 7583255 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 29429541 — Biomarker: PPARGC1A mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1
Study 29429541 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20576419 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 20576419 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12453546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29800370 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 22234929 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25265255 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10918483 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 19917839 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17029996 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10709897 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 7529606 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7529606 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7529606 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study 30016417 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 28672073 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 28672073 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 26582144 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9174677 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8251730 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20567009 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20567009 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 16042732 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 16042732 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8403135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4028514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10355479 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17342998 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7884745 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7884745 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28695567 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 16631435 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 4053509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15752943 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12022434 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1758240 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22461375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20619624 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8006396 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 2573379 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29260533 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29260533 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29260533 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 29260533 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29260533 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 25149364 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16791115 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 16791115 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 16791115 — Biomarker: ABCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 16791115 — Biomarker: ABCC4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC4; MOATB; MRP4
Study 14581931 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 28811749 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23217729 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 11751710 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9252087 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 9252087 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18545068 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9148534 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29258851 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 23006960 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30400858 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25715484 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17541206 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17541206 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15738287 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 22505251 — Biomarker: TNF-related weak inducer of apoptosis
Type: Predictive Biomarker (PRD)
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study 21829501 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21829501 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21829501 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 16758382 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14561107 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10988100 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10988100 — Biomarker: RNASE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RNASE2; EDN; RNS2
Study 22974968 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12749830 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 12749830 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26885697 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8228194 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8228194 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28992224 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28992224 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885
Study 28992224 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28992224 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25022840 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 25022840 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25022840 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 15661551 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 28531361 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 28531361 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20103777 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 20409883 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25347930 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 17459739 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 29658845 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29658845 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 20888255 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 19180322 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 30672056 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30672056 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 16216977 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16216977 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8006923 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 21975275 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9419773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8645022 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 23936895 — Biomarker: MSN mRNA
Type: Predictive Biomarker (PRD)
Genes: MSN
Study 10512913 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31500510 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 19390750 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21204677 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 1905472 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30918032 — Biomarker: Fibroblast growth factor 1
Type: Safety Biomarker (SAF)
Genes: FGF1
Study 2674593 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28141698 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 24432676 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 10082241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31260678 — Biomarker: PNPLA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PNPLA2; ATGL; FP17548
Study 31260678 — Biomarker: G0S2 mRNA
Type: Predictive Biomarker (PRD)
Genes: G0S2
Study 31260678 — Biomarker: PLIN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLIN1; PERI; PLIN
Study 31260678 — Biomarker: Angiopoietin-related protein 4
Type: Predictive Biomarker (PRD)
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 21883530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21883530 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21883530 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18178245 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10710121 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 25761488 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19800671 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19800671 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19800671 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8436150 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22897374 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 22897374 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22897374 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20708634 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 9487427 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8398959 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2439803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12927624 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 12927624 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 12927624 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 27634952 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 25670764 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 19903780 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19903780 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19903780 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16518754 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 12184546 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21310819 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17179269 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 22727160 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 19719551 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19719551 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 8646433 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 30004561 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30004561 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30004561 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24834977 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7141761 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27501160 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27501160 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16120823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16120823 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14506391 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 29261568 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 29261568 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25203878 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 7004723 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17647293 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12195129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7182376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24220392 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15303131 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 15303131 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 7723546 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7035040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24352352 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15887425 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15887425 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25735442 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 8612408 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 2859861 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15595331 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 12431962 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2996444 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 28229572 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 22221724 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS