AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 19617849 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28630081 — Biomarker: CASR mRNA
Type: Predictive Biomarker (PRD)
Genes: CASR; GPRC2A; PCAR1
Study 28630081 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 28630081 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 26188787 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 29096777 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 26296794 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 26296794 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12409281 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 11022421 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27795558 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 24461523 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9780616 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16600927 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16600927 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3882058 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25299401 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 22512843 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 10979901 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10979901 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 10979901 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8761839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1564133 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29949175 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 29949175 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22452356 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 22452356 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 6110954 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6110954 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31425383 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31425383 — Biomarker: Bacteroidetes phylum
Type: Safety Biomarker (SAF)
Study 22093930 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16788707 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28371811 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 28371811 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 18289903 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18289903 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17294991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31122893 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7758054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28905108 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 18950736 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17299073 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15203552 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15203552 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 15203552 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 15203552 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11593074 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 25671925 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24231018 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12668989 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 10376778 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29929610 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 28403850 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 28403850 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17509689 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17509689 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17509689 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30951501 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 30951501 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 30951501 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 30951501 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 30951501 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 30951501 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 30951501 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 11226652 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24958738 — Biomarker: miR-21
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR21
Study 24958738 — Biomarker: miR-214
Type: Safety Biomarker (SAF)
Genes: MIR214
Study 19640511 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19640511 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 24064695 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8896479 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25259747 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25259747 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22959763 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16079222 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 16079222 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20009091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31610637 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 31610637 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 24092475 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22331346 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22331346 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20591628 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 20591628 — Biomarker: LEPROT mRNA
Type: Predictive Biomarker (PRD)
Genes: LEPROT; LEPR; OBR
Study 24452943 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24452943 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 24452943 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24791969 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31634193 — Biomarker: CR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR2; C3DR
Study 31264761 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16581549 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8839903 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 9972889 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 2651767 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 31276981 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 16682611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27460675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21077043 — Biomarker: NOS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOS2; NOS2A
Study 15772062 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10048679 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2289214 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 27624622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20682612 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 20682612 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15146410 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15146410 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 9408807 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 31972315 — Biomarker: Chitinase-3-like protein 1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: CHI3L1
Study 31972315 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23850070 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 20504165 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20504165 — Biomarker: TLR9
Type: Predictive Biomarker (PRD)
Genes: CD289
Study 9289428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17413839 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9644639 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28399844 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28399844 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 28399844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9663825 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9663825 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9663825 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25842461 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 10081852 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 2349137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24050737 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 19338151 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19338151 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27384328 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 26175332 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 21196426 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 21196426 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 22819275 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20546545 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15823625 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15823625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7738683 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11732862 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 11732862 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 11732862 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 26764260 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22542362 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 22542362 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18317625 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18317625 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16046191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7793116 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 7344590 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22584195 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24667714 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24667714 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 9285079 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 15159414 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 7842354 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 10480346 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24176449 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 9241341 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 17008408 — Biomarker: PDE9A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE9A
Study 17008408 — Biomarker: PDE11A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE11A
Study 17008408 — Biomarker: PDE1A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE1A
Study 25422488 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25422488 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 23829417 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17552046 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17552046 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 11841770 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10682564 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10682564 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 2243264 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8092223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29804360 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28243834 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 28243834 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 9176035 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9176035 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19397474 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 19397474 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19397474 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7862712 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7862712 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25901093 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20957631 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 18033629 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9408932 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 2878746 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 2878746 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30229999 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 31277053 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 29062346 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25810066 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24044618 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24044618 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24044618 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31642426 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23766446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16824157 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 16824157 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16824157 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9330125 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29239515 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19231908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8897078 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 26077874 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26077874 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 25375279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31425453 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12575970 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12575970 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9605680 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9990211 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23756425 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23756425 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20058594 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26258571 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26258571 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 3288801 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25924841 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25924841 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 23588194 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 17604500 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15366593 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 7981002 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 18055296 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16086927 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12163792 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12163792 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10473964 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 2257858 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2959967 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 3829582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24929428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11752031 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18611068 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16025962 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 26039019 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 15047679 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7740961 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2