AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 11029555 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 3514487 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3514487 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 15679718 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12895452 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 30599803 — Biomarker: Tropomyosin-related kinase A
Type: Pharmacodynamic Biomarker (PDY)
Genes: NTRK1; MTC; TRK; TRKA
Study 26273669 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 21609640 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 27635609 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 27635609 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 27635609 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 23350203 — Biomarker: ABCC6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC6; ARA; MRP6
Study 21950726 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21950726 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 7942937 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8447567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3082613 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 26328636 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26328636 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 26328636 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21798556 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11382830 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 8299238 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8299238 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20598373 — Biomarker: CAMP mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMP; CAP18; FALL39; HSD26
Study 19096768 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 10229430 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8709356 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15814542 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 9453014 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 9453014 — Biomarker: MOXD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MOXD1; MOX; UNQ2493/PRO5780
Study 9453014 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7615046 — Biomarker: MEA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MEA1; MEA
Study 31554370 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 27522630 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 24492988 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 18445142 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10618463 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 22042967 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 9649964 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28474780 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24576893 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 28975305 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23343138 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17225260 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 9587124 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 26024532 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10825372 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 10825372 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 10825372 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 10825372 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 10825372 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 10825372 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 20444448 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12539003 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12539003 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12539003 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 12539003 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 12539003 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 8884643 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 28216550 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 24100259 — Biomarker: ADORA2A
Type: Safety Biomarker (SAF)
Genes: RDC8
Study 19214890 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 3902176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26148364 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 22785001 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 18186265 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 14669282 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 30557342 — Biomarker: C1QTNF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: C1QTNF3; CTRP3; UNQ753/PRO1484
Study 30557342 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 30557342 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 27095446 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21805294 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21805294 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15309001 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12040470 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 28044948 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20977584 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 20977584 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15794797 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8767527 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study 8767527 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 1678570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22865778 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 31550915 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23438946 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 15054349 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15054349 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15054349 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29044725 — Biomarker: Sclerostin
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: SOST; UNQ2976/PRO7455/PRO7476
Study 20602260 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9683118 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9160569 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 31134657 — Biomarker: CYP4F2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP4F2
Study 24045099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11498312 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17111013 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 17111013 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 17111013 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17111013 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 17111013 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11329095 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11329095 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7753432 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 21745769 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 23683569 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 19615135 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 19615135 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19615135 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2972540 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19230906 — Biomarker: PRPH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRPH2; PRPH; RDS; TSPAN22
Study 6100260 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3033966 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23615823 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23615823 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 14576512 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 2072368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27059799 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18628618 — Biomarker: NOS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOS3
Study 11315826 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11315826 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7868871 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7868871 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23834402 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 23834402 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 21756382 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 21756382 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 21756382 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 19629060 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16611682 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16611682 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 320955 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25349107 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 22285168 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31349110 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22458939 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2506490 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30844048 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 22732180 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 18042311 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11179910 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26588809 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19851858 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 11861035 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 9732842 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 30557370 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24081439 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 31955013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31955013 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31955013 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23265352 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 27397838 — Biomarker: EBP mRNA
Type: Predictive Biomarker (PRD)
Genes: EBP
Study 10450289 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1746296 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1746296 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30724405 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 6117576 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21136310 — Biomarker: MPG mRNA
Type: Predictive Biomarker (PRD)
Genes: MPG; AAG; ANPG; MID1
Study 21136310 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9081852 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22811376 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22811376 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15036828 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26202994 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9051332 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 10515442 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10515442 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29471922 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16103896 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 16103896 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12370520 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7572006 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 7572006 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 7270401 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7270401 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22402068 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18663625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18663625 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18663625 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3853254 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21999138 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 6496995 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12850395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10593371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19961932 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 16903931 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 29384321 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29384321 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16120821 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11865366 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 492050 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25889304 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15533488 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9659838 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28067195 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 26031921 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22350036 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 12692182 — Biomarker: HSPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPD1; HSP60
Study 12692182 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 18779278 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1934591 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 1934591 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 30689402 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28166116 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19132412 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15448032 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10353887 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 6627819 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25247320 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22770926 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2720018 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 30556110 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 9496202 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 28019134 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19276275 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 9163261 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3108429 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 3108429 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 18482245 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23025844 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19674927 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 27510285 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 20932272 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10102462 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 10102462 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12639763 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 12639763 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10928223 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26890438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24055515 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 22057579 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22057579 — Biomarker: HSPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPB1; HSP27; HSP28
Study 22057579 — Biomarker: HSPA1A mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA1A; HSP72; HSPA1; HSX70
Study 22057579 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 19288181 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8852495 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8852495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31004340 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS