AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 19010347 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19010347 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2522134 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25044345 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 21591986 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12619027 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 8626096 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 22574590 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22574590 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 22574590 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22574590 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8638531 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29178434 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 27495085 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23103485 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 18341655 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 18341655 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18341655 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC
Study 18341655 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 27495190 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31283865 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28801393 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17173662 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 17173662 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 22169130 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22169130 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15677511 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 15677511 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15677511 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9106790 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 31298466 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29362795 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 25594166 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22406434 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 22406434 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 22406434 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 28652968 — Biomarker: ITLN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITLN1; INTL; ITLN; LFR; UNQ640/PRO1270
Study 23242843 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17877128 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 18335515 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 10404825 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 10404825 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 17275896 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22997073 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8116352 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 9531581 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 28823927 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25624429 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11434728 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9700035 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 18571850 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 16020915 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16197815 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 16197815 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7747709 — Biomarker: TAOK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 6117684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23645692 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23645692 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23645692 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9688002 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 6356903 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15819974 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26468213 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18507270 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18507270 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1499364 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22751085 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 15598680 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7639218 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 29211953 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 20537748 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20537748 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25516625 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20829521 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 12867222 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8705639 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8705639 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 8705639 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31771589 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17693150 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15536539 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25393080 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15650984 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11786584 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9538979 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31828863 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23239836 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 19543080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11269535 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29250152 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29250152 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29250152 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 25711321 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20947492 — Biomarker: GAL3ST1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAL3ST1; CST
Study 10945091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31257439 — Biomarker: ASPSCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 31257439 — Biomarker: REST mRNA
Type: Predictive Biomarker (PRD)
Genes: REST; NRSF; XBR
Study 22198049 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22198049 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22198049 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 17385970 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17984132 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 8853730 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 6438683 — Biomarker: CPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPZ
Study 31256717 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29744647 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 17907109 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 17907109 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30268346 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28122337 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 28122337 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 6401908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25323254 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19124377 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 30256303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10321414 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25545313 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22622138 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22622138 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8770800 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 23421600 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25112372 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25112372 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19738493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20354006 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18764823 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8621129 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 8621129 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 8621129 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16916334 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 2109473 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9197016 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9197016 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20972736 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12448341 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22672359 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22672359 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10709370 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9071556 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 7527736 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 23388588 — Biomarker: FXYD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FXYD1; PLM
Study 14627440 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14627440 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9380298 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10554120 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10554120 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8622041 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8365461 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22343976 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 20186278 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20186278 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15980686 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12705178 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 12705178 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 28854580 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 26346470 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 26346470 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 23287836 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22724916 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 22724916 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21076271 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10736331 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8737101 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 23163142 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23163142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18083668 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15653517 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12567031 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 11815315 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 9710711 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7663660 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27869649 — Biomarker: TSLP mRNA
Type: Predictive Biomarker (PRD)
Genes: TSLP
Study 27869649 — Biomarker: KLRK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRK1; D12S2489E; NKG2D
Study 27869649 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26384238 — Biomarker: RARA mRNA
Type: Predictive Biomarker (PRD)
Genes: RARA; NR1B1
Study 26384238 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16621098 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 16621098 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29449506 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 29449506 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29188889 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16571878 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 14605279 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 8708224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9627274 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9627274 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 23334268 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 1425877 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1425877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31156013 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 25997746 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15016485 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11703421 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7536071 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24712568 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24712568 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9795914 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12518705 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 9381885 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 21383284 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 9551878 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30012268 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28965562 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 26485846 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 30573517 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 27000327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22789789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22789789 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9817281 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9817281 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30123250 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 24983542 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 24983542 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19602554 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19602554 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 8012963 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28028737 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 17204725 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 1525787 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2859042 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28371155 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26659938 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21658668 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 27301417 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19460715 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17627399 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29304531 — Biomarker: SKIL mRNA
Type: Predictive Biomarker (PRD)
Genes: SKIL; SNO
Study 23290154 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 31605923 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 23877621 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 30819077 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 30819077 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30819077 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15260911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11726259 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11726259 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 9159031 — Biomarker: F2R mRNA
Type: Predictive Biomarker (PRD)
Genes: F2R; CF2R; PAR1; TR
Study 9159031 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 9159031 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30144017 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 30144017 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 30144017 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 25654961 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 21323524 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 19369086 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14625708 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9494591 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 9494591 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9494591 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)