AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 20864405 — Biomarker: IGF1R mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1R
Study 20864405 — Biomarker: SOD2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SOD2
Study 20864405 — Biomarker: MYO5A mRNA
Type: Predictive Biomarker (PRD)
Genes: MYO5A; MYH12
Study 20864405 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 20864405 — Biomarker: Peroxisome proliferator-activated receptor delta
Type: Safety Biomarker (SAF)
Genes: PPARD
Study 20864405 — Biomarker: DNA repair endonuclease XPF
Type: Predictive Biomarker (PRD)
Genes: ERCC4; ERCC11; XPF
Study 20864405 — Biomarker: Aurora kinase A
Type: Predictive Biomarker (PRD)
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 30187872 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30187872 — Biomarker: AIP mRNA
Type: Predictive Biomarker (PRD)
Genes: AIP; XAP2
Study 22864036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26253869 — Biomarker: UMPS mRNA
Type: Predictive Biomarker (PRD)
Genes: UMPS; OK/SW-cl.21
Study 27680405 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 22386043 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18676075 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17705570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20691300 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 20691300 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18726564 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1677266 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 26712560 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24475026 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 12667322 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9707191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7661873 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 27722840 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23812272 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23812272 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20151997 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11007240 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 26251965 — Biomarker: IL13
Type: Predictive Biomarker (PRD)
Genes: P600; IL-13; ALRH; BHR1; MGC116786; MGC116788; MGC116789
Study 12392583 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 20168099 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9389780 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9389780 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29618017 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study 24216317 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 14563580 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28039902 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 26604652 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7041522 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7041522 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28372661 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15292307 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 26251958 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 16861405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10390546 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28968167 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24690021 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19394661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19394661 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15658652 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30623096 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19356075 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 19356075 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31037562 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 25418187 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 14523786 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14523786 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7752906 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 7752906 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7752906 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7011237 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31129681 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31129681 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29697876 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27492510 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 20577923 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 11771856 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23602770 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 8950732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6290228 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22382596 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 9921806 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 7573900 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30620668 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 30620668 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 24131674 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 7668036 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7192617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28166324 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14578410 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9049040 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18463885 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 16612257 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16612257 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10769011 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 10769011 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 3870921 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25135997 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 25135997 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15924587 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15924587 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7956631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18573713 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 9100037 — Biomarker: ERF mRNA
Type: Predictive Biomarker (PRD)
Genes: ERF
Study 8299406 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8299406 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 27267753 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 23492647 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16957573 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9024449 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22169794 — Biomarker: RAF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAF1; RAF
Study 18684771 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17313008 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 6388715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18797484 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31261928 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27484437 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21627458 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19755410 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 19755410 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17995584 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21831508 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21831508 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11788129 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11788129 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7882815 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7882815 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11083688 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 29415891 — Biomarker: SOCS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOCS1; SSI1; TIP3
Study 29415891 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 26721228 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 25948720 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23589106 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 18855824 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 14675918 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 31524075 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 17133211 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12940591 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10698133 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2875317 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28024882 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26744910 — Biomarker: MFF mRNA
Type: Predictive Biomarker (PRD)
Genes: MFF; C2orf33; AD030; AD033; GL004
Study 16277999 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16277999 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8824694 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28031053 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28031053 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 28031053 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 14555269 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 25952818 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19118844 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 9236432 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29173997 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29173997 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 29173997 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 29173997 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24159564 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 26931279 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8948272 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31335587 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 31335587 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25057173 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 25057173 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 22173910 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28866675 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28866675 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21816980 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 22879908 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 10905644 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9140791 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25795406 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 14555263 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31895884 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 20551833 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20551833 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16007101 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 14671611 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 27183343 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 11231393 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 6244920 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6244920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30389229 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30389229 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 30389229 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 30389229 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30389229 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27748235 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23823132 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 7912085 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3354029 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12545845 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19674252 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 17652885 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 17652885 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7772628 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23061430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19526756 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19526756 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19526756 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 19526756 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 16924025 — Biomarker: GABRG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GABRG2
Study 8198935 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27164434 — Biomarker: CYBB mRNA
Type: Predictive Biomarker (PRD)
Genes: CYBB; NOX2
Study 27164434 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 25326140 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 20057999 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30046129 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 19845969 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 9814469 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 7662600 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23619129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21411612 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 21411612 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 27624670 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19615130 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19615130 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10427657 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24146170 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21348207 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 19840533 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19840533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18423274 — Biomarker: EDA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDA; ED1; EDA2
Study 18423274 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25229168 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 25229168 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11475558 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 11475558 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31556787 — Biomarker: OGG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OGG1; MMH; MUTM; OGH1
Study 31556787 — Biomarker: PARP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PARP1; ADPRT; PPOL
Study 9419752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 55780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26199710 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25598314 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 21576052 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8782125 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8782125 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 29575708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20068568 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1