AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 11906645 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11906645 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10958254 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3209716 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 3209716 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23861381 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 20224007 — Biomarker: TLR2
Type: Predictive Biomarker (PRD)
Genes: TIL4; CD282
Study 10229128 — Biomarker: ERCC2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MAG; EM9; MGC102762; MGC126218; MGC126219
Study 10229128 — Biomarker: Peripheral myelin protein 22
Type: Pharmacodynamic Biomarker (PDY)
Genes: PMP22; GAS3
Study 31801679 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31801679 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 21632811 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8857677 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27669457 — Biomarker: MMD mRNA
Type: Predictive Biomarker (PRD)
Genes: MMD; PAQR11
Study 22248749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22248749 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9626770 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8070481 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8070481 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 7936364 — Biomarker: NCAM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NCAM1; NCAM
Study 26364532 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23884826 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15848527 — Biomarker: TFG mRNA
Type: Predictive Biomarker (PRD)
Genes: TFG
Study 27491605 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 25331468 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 20522795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1725913 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17609246 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 16306249 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 7790689 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29023536 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29023536 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17355745 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17355745 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17355745 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11465656 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9779342 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2861315 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30404626 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 17555385 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16378069 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2460291 — Biomarker: BAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAK1; BAK; BCL2L7; CDN1
Study 27634224 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27634224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27634224 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20059570 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20059570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10406358 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25329201 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 23155345 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 8848515 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 31284490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31284490 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31284490 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31284490 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 22678961 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22678961 — Biomarker: NR3C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR3C2; MCR; MLR
Study 12052850 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16781788 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21511218 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 18383517 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 16595223 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 26809009 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 23083841 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8726592 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8726592 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 6326784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30983953 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 25293442 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25293442 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25293442 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25293442 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17468667 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30282142 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 27784733 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16288616 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 7797058 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 16030053 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8955458 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 6181324 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31489467 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 31489467 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 31489467 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31489467 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 17585081 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 26509817 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 18206857 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10845350 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1610539 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 6428899 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 20447535 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 29077149 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29077149 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16717081 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 16717081 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 15259286 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 3901389 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31675674 — Biomarker: Carbonic anhydrase IX
Type: Predictive Biomarker (PRD)
Genes: CA9; G250; MN
Study 9554186 — Biomarker: SLC10A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC10A3; DXS253E; P3
Study 23735647 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 23735647 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22270380 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20604937 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18354383 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18354383 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12149529 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 12149529 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12149529 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 12149529 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 10102256 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10102256 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 10102256 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10102256 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8589555 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20705512 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 2109195 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29576354 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31334927 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26774526 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 26635308 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26635308 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 12655280 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12655280 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31369662 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 27806900 — Biomarker: PLXNA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 21600128 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18655554 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18655554 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 14502007 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10918470 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10918470 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 3145964 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 26224751 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 24877660 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24877660 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 24877660 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20512414 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 16078322 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10636369 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 15704046 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 4072939 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30404563 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study 30404563 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23670794 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 8200250 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28851800 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 11374850 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11374850 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1377484 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 6085377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31427869 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 20618359 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12463482 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6758935 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24743431 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24743431 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22052941 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 22052941 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 22052941 — Biomarker: MAOA mRNA
Type: Predictive Biomarker (PRD)
Genes: MAOA
Study 22052941 — Biomarker: S100A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: S100A4; CAPL; MTS1
Study 22052941 — Biomarker: SERPINB9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINB9; PI9
Study 22052941 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 22052941 — Biomarker: CTSL mRNA
Type: Predictive Biomarker (PRD)
Genes: CTSL; CTSL1
Study 22052941 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 22052941 — Biomarker: PAEP mRNA
Type: Predictive Biomarker (PRD)
Genes: PAEP
Study 22052941 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 22052941 — Biomarker: Clusterin
Type: Safety Biomarker (SAF)
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 2572266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 49737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22093054 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 12766641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9291200 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21122063 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21122063 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21122063 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18209255 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10886123 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8419226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8419226 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11176812 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 31159778 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10750252 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18924048 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16858168 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31449915 — Biomarker: TLR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR7; UNQ248/PRO285
Study 31449915 — Biomarker: TLR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR3
Study 8126533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2550402 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 21956711 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 21956711 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 19930832 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 8699777 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8699777 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23676961 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21886816 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16606934 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 8287573 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8287573 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 27210844 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 21178836 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 14627860 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 14627860 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10746534 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30326952 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 590301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27495295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10542973 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16723326 — Biomarker: AGL mRNA
Type: Predictive Biomarker (PRD)
Genes: AGL; GDE
Study 26123704 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 26123704 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 26123704 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 26123704 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 26123704 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 26123704 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 12795787 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 12795787 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 29428872 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17208410 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 28844118 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28844118 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23644901 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27255431 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 23777741 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23777741 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 16909131 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11302007 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8841501 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 8841501 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8841501 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 1623898 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 25695403 — Biomarker: CXCR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR2; IL8RB
Study 25695403 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14753029 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14753029 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 14753029 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 14753029 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2