AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 25271206 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22131908 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19184556 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 15001462 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 20066882 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20066882 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31446638 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22078152 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 29228247 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 19057612 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 30496407 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 24812896 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24812896 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18929701 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10510993 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10510993 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8748255 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8748255 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 15925955 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31291276 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22348910 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20102847 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20102847 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12598502 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12598502 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 12598502 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 12598502 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12598502 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12598502 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12598502 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 10100104 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18381952 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 10407522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8773212 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23580597 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17356086 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 1366257 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1366257 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16188771 — Biomarker: HLA-DQB1
Type: Safety Biomarker (SAF)
Genes: IDDM1; CELIAC1
Study 16188771 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11919120 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 11919120 — Biomarker: TEF mRNA
Type: Predictive Biomarker (PRD)
Genes: TEF; KIAA1655
Study 8521296 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8521296 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 27153360 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 25826143 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15472179 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11558856 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11558856 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31269876 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25108027 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23551723 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11012556 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 29699812 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 27003829 — Biomarker: TNFRSF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1A; TNFAR; TNFR1
Study 27003829 — Biomarker: TNFRSF1B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1B; TNFBR; TNFR2
Study 18555574 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18555574 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15290734 — Biomarker: SLAMF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLAMF1; SLAM
Study 11263764 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9146328 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 8174879 — Biomarker: LGALSL mRNA
Type: Predictive Biomarker (PRD)
Genes: LGALSL; GRP; HSPC159
Study 29494855 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29494855 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24196521 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24196521 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21641365 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19365563 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9210690 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3144919 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22949472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15499622 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 18317253 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 17129496 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12840632 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 6541538 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11689299 — Biomarker: Lysosomal acid glucosylceramidase
Type: Pharmacodynamic Biomarker (PDY)
Genes: GBA1; GBA; GC; GLUC
Study 26889783 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 26889783 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 26215196 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 19034875 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10881066 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 1974506 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7030149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10389774 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10389774 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 10389774 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20660830 — Biomarker: MYCN mRNA
Type: Predictive Biomarker (PRD)
Genes: MYCN; BHLHE37; NMYC
Study 18413423 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 12439845 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10529135 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 22976566 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 9417816 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9417816 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9417816 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28207505 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 22959634 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17028221 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 29173604 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29173604 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23169517 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 23169517 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28157380 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20001460 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11501230 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11501230 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23885614 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25617577 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 11642001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30402489 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21856022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10913939 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 30867552 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 18823468 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18823468 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14684754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31869338 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27010951 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25193393 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25193393 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31719084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30188495 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26709933 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17601803 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 15465623 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7888256 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 28290994 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22434361 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22434361 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19337745 — Biomarker: PCLO mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLO; ACZ; KIAA0559
Study 15623613 — Biomarker: FMO3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMO3
Study 10510926 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 31046700 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 28538361 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23479383 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 18800142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9773780 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 16331116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8833216 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 8833216 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3926567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12048320 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31498125 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31498125 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 26514213 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 22546942 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22546942 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 22546942 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 22546942 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 20721930 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15247755 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 9439492 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9439492 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15892085 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10862528 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26247960 — Biomarker: PLAT mRNA
Type: Predictive Biomarker (PRD)
Genes: PLAT
Study 22658422 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16249738 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12152001 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30562710 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28434467 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12394804 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12394804 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31916229 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25200354 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22733398 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 22733398 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 22733398 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 30466421 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2638619 — Biomarker: DTL mRNA
Type: Predictive Biomarker (PRD)
Genes: DTL; CDT2; CDW1; DCAF2; L2DTL; RAMP
Study 23808439 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23808439 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21653833 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19543851 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 19543851 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 16423676 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11737373 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9506654 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9506654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28824296 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 6602783 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20837645 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 20837645 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 16224161 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 16224161 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16224161 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22985270 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15448036 — Biomarker: FLT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT4; VEGFR3
Study 15448036 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 12095057 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12095057 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 2339965 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17188121 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 2907408 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16875041 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16875041 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10773785 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 10773785 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 8638533 — Biomarker: Arachidonate 5-lipoxygenase activating protein
Type: Safety Biomarker (SAF)
Genes: ALOX5AP; FLAP
Study 8102631 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8102631 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 21606869 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19115653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10966535 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 29322301 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 29322301 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 18832434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15957829 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 6233546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18696354 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18696354 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18696354 — Biomarker: GSTA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTA1
Study 18696354 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8672931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1828309 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7104157 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 7104157 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7104157 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7104157 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7104157 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27834446 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20631056 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15734599 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12472620 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 29098381 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 20151824 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 18292586 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 18292586 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17196519 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12192663 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 7551660 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7551660 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7551660 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7551660 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 2192197 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 715133 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7922005 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 7922005 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 21531236 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9082588 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1