AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24213955 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 2188845 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 2188845 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17013645 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9701528 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 30695420 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26089547 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 21624541 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 19364997 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11406520 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11406520 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11406520 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 2974095 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 2974095 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2974095 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22381025 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22381025 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18046109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15272291 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7597608 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 30987164 — Biomarker: miR-423
Type: Safety Biomarker (SAF)
Genes: MIR423
Study 30987164 — Biomarker: let-7a
Type: Safety Biomarker (SAF)
Study 30987164 — Biomarker: miR-26a
Type: Monitoring Biomarker (MOI)
Study 11867933 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11867933 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11867933 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 6772045 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23660512 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23660512 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16801586 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12756090 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 8103820 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14618470 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26519996 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10325501 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 10325501 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 1422748 — Biomarker: PGR mRNA
Type: Predictive Biomarker (PRD)
Genes: PGR; NR3C3
Study 15642073 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10082501 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7579751 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 22389220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15159307 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 15159307 — Biomarker: TGFB1
Type: Safety Biomarker (SAF)
Genes: CED; TGFbeta
Study 12428241 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9839295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30326045 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 12578880 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10386412 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 10386412 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 21332346 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 11521964 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11521964 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 21534836 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19559166 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26842950 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 21907450 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21907450 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18184542 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18184542 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 18184542 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18184542 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18184542 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11530030 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 31980978 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 30219400 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 17138219 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 12753370 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 28303753 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25085943 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18422837 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 18422837 — Biomarker: MMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP2; CLG4A
Study 18422837 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 12559133 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17700386 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 10503666 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26580123 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 10397695 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 10397695 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2202458 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23642776 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 23642776 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 21276616 — Biomarker: AXL mRNA
Type: Predictive Biomarker (PRD)
Genes: AXL; UFO
Study 19995648 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19995648 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19995648 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 1406416 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31748169 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24398943 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 12517681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30939472 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 30939472 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 30939472 — Biomarker: Chitinase-3-like protein 1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: CHI3L1
Study 27943617 — Biomarker: TNFRSF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1A; TNFAR; TNFR1
Study 27943617 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27943617 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9862770 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30141776 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 21426884 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21426884 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21426884 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 18411913 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 27928115 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27928115 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 19347813 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 12050268 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10968690 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23238930 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 23238930 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 25495610 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25495610 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 17914031 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 7944428 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 29919984 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29919984 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7988260 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 30060100 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23866813 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19673328 — Biomarker: STC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STC1; STC
Study 8912742 — Biomarker: MEFV mRNA
Type: Predictive Biomarker (PRD)
Genes: MEFV; MEF; TRIM20
Study 15802770 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8784330 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31209191 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27889832 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 27889832 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 23656463 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19622007 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17597499 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17597499 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 8483018 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8483018 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24829497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23842679 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 23842679 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 3113778 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 28605158 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 26426277 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8239200 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27645318 — Biomarker: XG mRNA
Type: Predictive Biomarker (PRD)
Genes: XG; PBDX
Study 27645318 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 25307414 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 20668444 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 20668444 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 10365287 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15134183 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3353874 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11464618 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 20398258 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12003160 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9797978 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 29231496 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 29231496 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 8916815 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12221462 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 24048291 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20876406 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30651324 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 22694918 — Biomarker: ADRA2A mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRA2A; ADRA2R; ADRAR
Study 21127898 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21127898 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15500630 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 24255934 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 18230968 — Biomarker: FMN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMN1; FMN; LD
Study 28321995 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 25795452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23442248 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24391142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18511473 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18511473 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12699514 — Biomarker: MMP12 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP12; HME
Study 1430283 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 21900640 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19491910 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 3300967 — Biomarker: STUB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STUB1; CHIP; PP1131
Study 24934544 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 9733448 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9733448 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9733448 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9733448 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30032842 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 30032842 — Biomarker: FGFR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 30032842 — Biomarker: PDGFD mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFD; IEGF; SCDGFB; MSTP036; UNQ1899/PRO4345
Study 30032842 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 24770930 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24770930 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17638141 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11332356 — Biomarker: AOX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AOX1; AO
Study 29080069 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29080069 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9385891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20932157 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 19535691 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16926245 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 11701677 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8185744 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10831641 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 2857901 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 1894296 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24120264 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22260859 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28920458 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28920458 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10212103 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 8729126 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8729126 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1422714 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4046122 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30140328 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 22142823 — Biomarker: CCR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 20549832 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16206600 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30168611 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 19814804 — Biomarker: EPHX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPHX2
Study 24456422 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 24456422 — Biomarker: Osteopontin
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SPP1; BNSP; OPN; PSEC0156
Study 16310197 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 24085401 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24085401 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17785930 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17785930 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17785930 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11178767 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11178767 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9710029 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 7526676 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21751904 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 16912265 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 16225723 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23706899 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 19191743 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 19191743 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28437263 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25675222 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16828500 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 16828500 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15342284 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2