AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23359067 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 15533869 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 15533869 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11287377 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 15718040 — Biomarker: SLC1A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC1A3; EAAT1; GLAST; GLAST1
Study 23943468 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16496019 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31362877 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31362877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28558139 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 11877068 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9626635 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 23577799 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7625415 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29898452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23563134 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21070457 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16564798 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16564798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12548091 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 11007152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1548570 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26270552 — Biomarker: F7 mRNA
Type: Predictive Biomarker (PRD)
Genes: F7
Study 26270552 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 23963138 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23963138 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17006711 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study 17006711 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8650428 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8650428 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25327602 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 14710168 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8435362 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23364390 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 23364390 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 19112496 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 1832291 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 29215302 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 20156032 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20156032 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20156032 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18587307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15687321 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8725495 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 15607123 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 25641452 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 29738412 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 29738412 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 26994987 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 25265572 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 31247674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21272190 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19812809 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20309682 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study 10822318 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29138201 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2988769 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12830470 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7595137 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 29701801 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3276167 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12364634 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28953776 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 28953776 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 21247431 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21247431 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 21247431 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19140906 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9920070 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9920070 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7703390 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25593284 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study 25593284 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21817821 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16886114 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9275110 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2646315 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 2646315 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28609567 — Biomarker: PTGDR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 19949272 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17044661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11181371 — Biomarker: MPG mRNA
Type: Predictive Biomarker (PRD)
Genes: MPG; AAG; ANPG; MID1
Study 8282435 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26281326 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 8704064 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 6748070 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29750632 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 18034867 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8746602 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27840301 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24691140 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19543672 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9558774 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 19885850 — Biomarker: Cyclin-dependent kinase inhibitor 1
Type: Safety Biomarker (SAF)
Genes: CDKN1A
Study 24694667 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 15740629 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 15740629 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 22831916 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22831916 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 1326318 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30058112 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 30058112 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 19864941 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19864941 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 19864941 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 19864941 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 17571741 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15661814 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 15661814 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 15661814 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 15661814 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2148326 — Biomarker: AMPH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMPH; AMPH1
Study 27866347 — Biomarker: HSPA1B mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA1B; HSP72
Study 25562579 — Biomarker: PICALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PICALM; CALM
Study 25562579 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 17045352 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17045352 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15325679 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 2459516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21354122 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12967481 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10882962 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1382623 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1382623 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 4005083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3505604 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 27621026 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27621026 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 20924261 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 9144368 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29794482 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16982961 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 16982961 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 16982961 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15309217 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15309217 — Biomarker: ZFP36 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 11555394 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11555394 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3060987 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 18306871 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18306871 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9661597 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2729123 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18813182 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18813182 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16543714 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 14526263 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 8982557 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1468827 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 1468827 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26557703 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23053266 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 8129324 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26215945 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26215945 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 26215945 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 2116817 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2116817 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 16618293 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27956763 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27956763 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15605190 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29545413 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 30072191 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22146491 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 20637495 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 20637495 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10673673 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 3519766 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3519766 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11155088 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 9059953 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29528986 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18372218 — Biomarker: CALD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CALD1; CAD; CDM
Study 27925283 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 26156311 — Biomarker: TBCA mRNA
Type: Predictive Biomarker (PRD)
Genes: TBCA
Study 19554090 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18093504 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11748341 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28093041 — Biomarker: ISM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ISM1; C20orf82; ISM
Study 19583077 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11722052 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9142583 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29360932 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29360932 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28656452 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 24862944 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 19120717 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14599408 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24336915 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 24336915 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24336915 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 24336915 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16365072 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 14551359 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14551359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18057309 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 8464662 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 20204340 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20204340 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20204340 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7546497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31111678 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22174431 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19047289 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 10457212 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 10457212 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8547546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19252142 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17106312 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7197978 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31418881 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 25618516 — Biomarker: FGF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF5
Study 25618516 — Biomarker: ATP2B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATP2B1; PMCA1
Study 21873796 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 15522140 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29987109 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 29987109 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 29987109 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26778538 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 25019209 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 25019209 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 12185609 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9466021 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23864786 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 9614361 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 1920344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20634651 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20634651 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16037885 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16037885 — Biomarker: CKM mRNA
Type: Predictive Biomarker (PRD)
Genes: CKM; CKMM
Study 12388959 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12388959 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 6127906 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30929268 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30929268 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 29202751 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29202751 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21167906 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 19880052 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16111901 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24213955 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF