AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 8797513 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25483700 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25483700 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 20400899 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 16083996 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 12442956 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9809623 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18343245 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18343245 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12784090 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 17823506 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12463460 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12463460 — Biomarker: TNFR1B
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 10516691 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10516691 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10516691 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21938072 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31861026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17079994 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2751476 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25987796 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21466598 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21466598 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21466598 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28851037 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27662556 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12213870 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 25399552 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 22152871 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 11413357 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9404429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8236548 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 8236548 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26968380 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 26968380 — Biomarker: Cardiac troponin T
Type: Safety Biomarker (SAF)
Genes: TNNT2
Study 15761191 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 12454555 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 6108592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23959833 — Biomarker: MTRR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTRR
Study 23959833 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 23959833 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 19584831 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 27330807 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 18300236 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 18300236 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18300236 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 12796772 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 12796772 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11195956 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 7840401 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22884532 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21481414 — Biomarker: TTN mRNA
Type: Predictive Biomarker (PRD)
Genes: TTN
Study 15938534 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15938534 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10369282 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2310248 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 30641712 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9923765 — Biomarker: DSP mRNA
Type: Predictive Biomarker (PRD)
Genes: DSP
Study 9923765 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9923765 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9923765 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29273661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29273661 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9686497 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 26109470 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9404251 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 3099651 — Biomarker: TAOK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 26982618 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26982618 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22394534 — Biomarker: TERT mRNA
Type: Predictive Biomarker (PRD)
Genes: TERT; EST2; TCS1; TRT
Study 22394534 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 19294859 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19294859 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19294859 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7475139 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27111239 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10480411 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10480411 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 6958191 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6958191 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 6958191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15044205 — Biomarker: C-X-C motif chemokine 11
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 15044205 — Biomarker: C-X-C motif chemokine 5
Type: Safety Biomarker (SAF)
Genes: CXCL5; ENA78; SCYB5
Study 15044205 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 15044205 — Biomarker: Platelet-derived growth factor B
Type: Pharmacodynamic Biomarker (PDY)
Genes: PDGFB; PDGF2; SIS
Study 20501957 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 11120523 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 26822146 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 26822146 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 19458961 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14726297 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11206672 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30018118 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 30018118 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 30018118 — Biomarker: CDX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDX2; CDX3
Study 6986893 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23375753 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31310919 — Biomarker: FGR mRNA
Type: Predictive Biomarker (PRD)
Genes: FGR; SRC2
Study 25847553 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25847553 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23361504 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 23361504 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 9088589 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8227803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3100446 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 14694037 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study 3803413 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30181085 — Biomarker: IGFBP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP7; MAC25; PSF
Study 30181085 — Biomarker: TIMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TIMP2
Study 25464446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19774841 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17469765 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17469765 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10030097 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8047525 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8047525 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7865685 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 7865685 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7865685 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31784483 — Biomarker: Lysosomal acid glucosylceramidase
Type: Pharmacodynamic Biomarker (PDY)
Genes: GBA1; GBA; GC; GLUC
Study 28137734 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 21104041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17126767 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17126767 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11451296 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8918495 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 6810904 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 24378016 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21699447 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12488649 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27836866 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 25861467 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 25861467 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15311169 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15311169 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2952095 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 23252284 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23252284 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19336536 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 15151614 — Biomarker: LAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LAT
Study 25108889 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 22412073 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17386092 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12138952 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12138952 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12138952 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28235526 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26032587 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26032587 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15147430 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 15147430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20126911 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 10943869 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 29798500 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 25009971 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18674411 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30693979 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 30693979 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 16198653 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 1787651 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 19947365 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 19947365 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 17456483 — Biomarker: RRAD mRNA
Type: Predictive Biomarker (PRD)
Genes: RRAD; RAD
Study 31584063 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31584063 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 31584063 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19687522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11929022 — Biomarker: CMC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CMC2; C16orf61; DC13
Study 11929022 — Biomarker: CMC4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CMC4; C6.1B; MTCP1; MTCP1NB
Study 19076110 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15051744 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 31115462 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 28291866 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15182772 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7905143 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24674676 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24674676 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1974484 — Biomarker: ABL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABL2; ABLL; ARG
Study 28447625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21777972 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12536495 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3453385 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22922591 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19695390 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11511139 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26739393 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25128203 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 25128203 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25128203 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 25128203 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 26526623 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 26526623 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 26526623 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21399536 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18097109 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1154272 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29225313 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26514447 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 26514447 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 22462558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10227808 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 10227808 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 10227808 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24643636 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24643636 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24643636 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 24643636 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 12200521 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28335893 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 1810018 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 6285503 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 30730862 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 23896791 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 8005300 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 28368486 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 24026893 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 24026893 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21566104 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 12548298 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25504080 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12414334 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 10078679 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24338139 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 332471 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 332471 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 24195786 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19957508 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16886116 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study 27180949 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1619181 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12783111 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 12783111 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 29869004 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 21117407 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10953902 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29634086 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1