AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 28545189 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 19273701 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 19273701 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 11167370 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9129487 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3729666 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 22412041 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22412041 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 18072873 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 16794892 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12634875 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30379814 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 23514685 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 23514685 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16248952 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16248952 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28968735 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28968735 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12713766 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 7828254 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23751021 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 19661244 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 9595647 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7945475 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2835890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2835890 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 2835890 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28855173 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28855173 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29019365 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 29019365 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29019365 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 24365871 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9647493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9647493 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9340029 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2777011 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24612734 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 18718737 — Biomarker: SDC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SDC1; SDC
Study 24659064 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15892276 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15892276 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15262838 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9734727 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 3402466 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3402466 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 8336373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3459351 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3459351 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 3459351 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3459351 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 19307503 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 19307503 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 11134438 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 21295507 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21295507 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21295507 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16966690 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 10699943 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 29530933 — Biomarker: CDKN1B mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN1B; KIP1; p27
Study 29530933 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29530933 — Biomarker: TOP2A mRNA
Type: Predictive Biomarker (PRD)
Genes: TOP2A; TOP2
Study 29530933 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 19853420 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 19853420 — Biomarker: Coagulation factor Va
Type: Safety Biomarker (SAF)
Genes: F5
Study 7916403 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 20594330 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 20594330 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 9477056 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7890075 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 1854108 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27687644 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22137512 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15037490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21834489 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8353046 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 8353046 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 25801652 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 21696241 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11728044 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8493292 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 29676972 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 25029008 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25029008 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25029008 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 25029008 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 16171665 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 19638647 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 821075 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 18339606 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 18339606 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 18339606 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18339606 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 3354431 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28126600 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24689056 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 24689056 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 16118079 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22166241 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 30215545 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 25027335 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 25027335 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 25027335 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 15834239 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 10778622 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 8580384 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 8580384 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8580384 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8580384 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23778325 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 23778325 — Biomarker: PTGS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGS1; COX1
Study 23778325 — Biomarker: ALOX12 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALOX12; 12LO; LOG12
Study 23778325 — Biomarker: PTGES mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGES; MGST1L1; MPGES1; PGES; PIG12
Study 23778325 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23778325 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 23778325 — Biomarker: GPX3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPX3; GPXP
Study 21262886 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 17324745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15054155 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2658886 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31819387 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26698120 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24026599 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12698670 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 12698670 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12698670 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8616947 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1412677 — Biomarker: ZFP36 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 2637586 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 29768118 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 21778912 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21778912 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16938161 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 16938161 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 2035380 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28252827 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 16322283 — Biomarker: ELAPOR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELAPOR1; EIG121; KIAA1324; UNQ2426/PRO4985
Study 12081832 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 7871564 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27984005 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3161422 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29799668 — Biomarker: TKTL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TKTL1; TKR; TKT2
Study 19487582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3530447 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 3530447 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24650009 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12566361 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 12566361 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 12566361 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10225081 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 29042662 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22824097 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19615091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15073704 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9509951 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 9509951 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 27651218 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27651218 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27651218 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27651218 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10918423 — Biomarker: THPO mRNA
Type: Predictive Biomarker (PRD)
Genes: THPO; MGDF
Study 19927151 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885
Study 19927151 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19927151 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10663062 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 8851595 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22984233 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20733134 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 9848502 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9848502 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 31129587 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 29525602 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29525602 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26404015 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 17261329 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 11669361 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20921462 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20921462 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 8614068 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9683043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26314389 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 21544559 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18438876 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 10882619 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29450636 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 26826547 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 11973420 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 10361110 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8729953 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 1710823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22338959 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16986228 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30772975 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 8530644 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 27745532 — Biomarker: VASH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VASH1; KIAA1036; VASH
Study 23115085 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 23115085 — Biomarker: SLCO1B3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 23115085 — Biomarker: SLC47A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC47A1; MATE1
Study 31393378 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 18596668 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16926119 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15083986 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9496526 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 2647270 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 30159779 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 30159779 — Biomarker: TERT mRNA
Type: Predictive Biomarker (PRD)
Genes: TERT; EST2; TCS1; TRT
Study 30159779 — Biomarker: CCL22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 30159779 — Biomarker: Tumor-infiltrating lymphocyte
Type: Predictive Biomarker (PRD)
Study 25408735 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 7586436 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7586436 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7586436 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 22326504 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 22326504 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 2994148 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2994148 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30832742 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30832742 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 20375405 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10843434 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 28953631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3059852 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24079465 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28623954 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 28623954 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21185229 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19695029 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11986408 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11986408 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28467150 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28467150 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16927283 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 3310159 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 7676778 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19621678 — Biomarker: MLH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MLH1; COCA2
Study 19621678 — Biomarker: DNA mismatch repair protein MSH2
Type: Predictive Biomarker (PRD)
Genes: MSH2
Study 19621678 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 11171785 — Biomarker: HES1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HES1; BHLHB39; HL; HRY