AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 12079904 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8589769 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2162877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27007989 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27007989 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 16301884 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11896441 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 2533582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 342627 — Biomarker: Preexisting antibody
Type: Safety Biomarker (SAF)
Study 31096775 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 23616126 — Biomarker: CGN mRNA
Type: Predictive Biomarker (PRD)
Genes: CGN; KIAA1319
Study 12473554 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 7707809 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 7707809 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26574625 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24297579 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 3553478 — Biomarker: SLC5A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A5; NIS
Study 3553478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24124358 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 20377577 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1581404 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 3878682 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 17631074 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17631074 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17631074 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 16133688 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7669374 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26912209 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 11897643 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10193670 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2268940 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7040142 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7999599 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 10690937 — Biomarker: GCSAM mRNA
Type: Predictive Biomarker (PRD)
Genes: GCSAM; GAL; GCET2
Study 10690937 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 10488967 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 28381584 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17261336 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17261336 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14692040 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 7542109 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 14727010 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 14727010 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11758675 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study 31487797 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31487797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26025412 — Biomarker: POR mRNA
Type: Predictive Biomarker (PRD)
Genes: POR; CYPOR
Study 14634679 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14634679 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1627372 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9220520 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 8427515 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 18291017 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 16188911 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 18360062 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16789979 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 16789979 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16789979 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22294639 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15958361 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 19237811 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16236942 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16236942 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 16236942 — Biomarker: Alpha-glutathione S-transferase
Type: Safety Biomarker (SAF)
Study 2316014 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19325138 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15916851 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17294139 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17294139 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 2226538 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 374444 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28625256 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28625256 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25736441 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 19327603 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 19327603 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 18614721 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 15824925 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 30601319 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9258888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8488820 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 25572279 — Biomarker: SPARC mRNA
Type: Predictive Biomarker (PRD)
Genes: SPARC; ON
Study 16183188 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16183188 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15169798 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 3306289 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21951314 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 21951314 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 28989140 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 26280247 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24074738 — Biomarker: DDO mRNA
Type: Predictive Biomarker (PRD)
Genes: DDO
Study 17368881 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17368881 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17368881 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 2898717 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 2898717 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 31980022 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31980022 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31980022 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25602854 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25602854 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25602854 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19388074 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 8527004 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 8527004 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 2054690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24617449 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 10834505 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 31624844 — Biomarker: SH2B3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SH2B3; LNK
Study 31624844 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31624844 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31624844 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 1391062 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12369732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30202902 — Biomarker: FFAR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FFAR4; GPR120; GPR129; O3FAR1; PGR4
Study 25283139 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8470789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2951261 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22197217 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22197217 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 22197217 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 11124745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25662105 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1316307 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1316307 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study 31357949 — Biomarker: ANKS4B mRNA
Type: Predictive Biomarker (PRD)
Genes: ANKS4B; HARP
Study 29316236 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17391324 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 17391324 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 14966345 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9639377 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 24283172 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 18462083 — Biomarker: GSS mRNA
Type: Predictive Biomarker (PRD)
Genes: GSS
Study 8960948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28689679 — Biomarker: CPE mRNA
Type: Predictive Biomarker (PRD)
Genes: CPE
Study 25496464 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25496464 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19631946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9716583 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 3230200 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 30482460 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 19917874 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12039398 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8607618 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 30545701 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25682576 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 8424510 — Biomarker: PTN mRNA
Type: Predictive Biomarker (PRD)
Genes: PTN; HBNF1; NEGF1
Study 27281019 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 27281019 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 27281019 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 19420283 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 19420283 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19420283 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16883525 — Biomarker: CDX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDX2; CDX3
Study 16883525 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 16883525 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7515652 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 28678568 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28678568 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 28678568 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 24916786 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 12798752 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 25464675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20167156 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25869509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16308413 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9532517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8300487 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31870942 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18981372 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 24385236 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24385236 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24385236 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16015004 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16015004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16015004 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12359651 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 1467074 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29508715 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 24389416 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24389416 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24389416 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 22878803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20230461 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 8996294 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8996294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21321419 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 19301059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30679439 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30679439 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 30679439 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 1290169 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 29494727 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21415158 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 19480671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9071430 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2464358 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 12708879 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31683942 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 20153900 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 394062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21443321 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 7683553 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3333522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26916794 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 26916794 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22218160 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22218160 — Biomarker: TLR2
Type: Predictive Biomarker (PRD)
Genes: TIL4; CD282
Study 19949851 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10653831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8842352 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8842352 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 31136218 — Biomarker: DNM1L mRNA
Type: Predictive Biomarker (PRD)
Genes: DNM1L; DLP1; DRP1
Study 31136218 — Biomarker: SLC25A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A4; AAC1; ANT1
Study 27603149 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 27603149 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22017999 — Biomarker: RTN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RTN1; NSP
Study 15481160 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29073629 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20029516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16304572 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 822857 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 26416895 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 26416895 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21523716 — Biomarker: SPARC mRNA
Type: Predictive Biomarker (PRD)
Genes: SPARC; ON
Study 16713529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11146520 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 25141922 — Biomarker: FST mRNA
Type: Predictive Biomarker (PRD)
Genes: FST
Study 2856710 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30888598 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 30888598 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 21437603 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 16541115 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 1600704 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20560409 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16916339 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 158003 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 31350270 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7816518 — Biomarker: COL1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL1A1
Study 1669517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6762807 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6762807 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 6762807 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31585544 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 19397224 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19397224 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19397224 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16856571 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 23328000 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23328000 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11758626 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)