AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 7837398 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14687246 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11398072 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 23835245 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23835245 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23835245 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21592110 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 9246969 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 9246969 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31704159 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29258541 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26265274 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8087360 — Biomarker: DDR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 2697584 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 24136634 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 21654506 — Biomarker: MECP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MECP2
Study 8229908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26290275 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26290275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21224376 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 21224376 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21224376 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 21224376 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 21224376 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 16199916 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11980131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27912934 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 23954450 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18262663 — Biomarker: DRD3
Type: Safety Biomarker (SAF)
Study 23070486 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 21073556 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 21073556 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9852390 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9852390 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 23706946 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 23706946 — Biomarker: HTRA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HTRA1; HTRA; PRSS11
Study 23706946 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 19080748 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9602314 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 24783193 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 24783193 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24783193 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9278463 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16770291 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23647738 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 23647738 — Biomarker: ABL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABL2; ABLL; ARG
Study 18617304 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 8439021 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 26827289 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11943529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 241365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24961537 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20441243 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 20441243 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20441243 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 20441243 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1899823 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 30634590 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22752690 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 15084930 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15084930 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 15084930 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15084930 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 313717 — Biomarker: Succinate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: SDHD
Study 31023272 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31023272 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 25540059 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22528588 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19008491 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19008491 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 19008491 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19008491 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 11716313 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11716313 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11716313 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27860410 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27860410 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25459913 — Biomarker: Sclerostin
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: SOST; UNQ2976/PRO7455/PRO7476
Study 19041436 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19041436 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25886378 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 21480416 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21480416 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 2864374 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27664491 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 22124524 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 26871245 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26871245 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22006544 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15470286 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24594863 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24594863 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24594863 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31829793 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31829793 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 31829793 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 19649309 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19649309 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9601649 — Biomarker: CA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA1
Study 7721516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7721516 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23893223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12972684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12972684 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9101374 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24705678 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 25649195 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 11583720 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11583720 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25539931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24166760 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 7796569 — Biomarker: CENPJ mRNA
Type: Predictive Biomarker (PRD)
Genes: CENPJ; CPAP; LAP; LIP1
Study 28045335 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 28045335 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 14769702 — Biomarker: ABCG5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG5
Study 26386635 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 11745278 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 9052812 — Biomarker: CNTF mRNA
Type: Predictive Biomarker (PRD)
Genes: CNTF
Study 9052812 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21745832 — Biomarker: GSS mRNA
Type: Predictive Biomarker (PRD)
Genes: GSS
Study 26743526 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17615501 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 12616822 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 12616822 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21228267 — Biomarker: CFTR
Type: Predictive Biomarker (PRD)
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 19098076 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8839196 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 1451816 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 2874067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2874067 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24329506 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 409101 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 30291545 — Biomarker: THBS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: THBS1; TSP; TSP1
Study 19330600 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28131433 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28395507 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 26627878 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2853406 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16335682 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22035826 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17071205 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21625881 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18630772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1787609 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 7019839 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21135055 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 11777489 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 9258415 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27733375 — Biomarker: HMBS mRNA
Type: Predictive Biomarker (PRD)
Genes: HMBS; PBGD; UPS
Study 11867404 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11867404 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 11867404 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24691248 — Biomarker: PLB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLB1; PLB
Study 7585063 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 7585063 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 10532692 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2284219 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7457801 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 26970404 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 28792851 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28792851 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28792851 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24146218 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29029101 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15297066 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24793528 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 8021054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21983163 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21983163 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21983163 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21983163 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18445991 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 25244260 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16438016 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29465346 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29465346 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29465346 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27344118 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 7688829 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 7688829 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 28329346 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 28329346 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 17623225 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31219734 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15988706 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15988706 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7815337 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24517155 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 17559146 — Biomarker: Dihydrothymine dehydrogenase
Type: Safety Biomarker (SAF)
Genes: DPYD
Study 16293862 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16293862 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 9542477 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 2646839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28662049 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 26199386 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 22228829 — Biomarker: HTR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2A; HTR2
Study 22228829 — Biomarker: HTR2C mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2C; HTR1C
Study 22228829 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 22228829 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 15076170 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 15076170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27855103 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 25336055 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17962632 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 1410588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2676659 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31429198 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26223240 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17250464 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 17250464 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15736476 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study 12062150 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 7783410 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27860389 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27860389 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27860389 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 9681721 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 31725319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17074775 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17074775 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9258853 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28365177 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3538802 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12953018 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10844829 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30408621 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20068208 — Biomarker: MAVS mRNA
Type: Predictive Biomarker (PRD)
Genes: MAVS; IPS1; KIAA1271; VISA
Study 8641322 — Biomarker: DDR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 8641322 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 8641322 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2138704 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2138704 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6158390 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 25981651 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 18997196 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18997196 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10202985 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10202985 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 7595908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28803124 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 23437966 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1