AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 30253197 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 31656094 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22137666 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 11291084 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11291084 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11291084 — Biomarker: RAS peptides
Type: Pharmacodynamic Biomarker (PDY)
Study 1093464 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 19365652 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16704952 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15081455 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 15081455 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15081455 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7899862 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 28049642 — Biomarker: ELN mRNA
Type: Predictive Biomarker (PRD)
Genes: ELN
Study 28049642 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 23063625 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21750266 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 21750266 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19401659 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 15290395 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 9469797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9469797 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8194494 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 21906391 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21906391 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3883767 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 19037084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9551877 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9551877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26873681 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26873681 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 26873681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25046547 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16866686 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 3937598 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 22613197 — Biomarker: CENPJ mRNA
Type: Predictive Biomarker (PRD)
Genes: CENPJ; CPAP; LAP; LIP1
Study 7491697 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 7491697 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 25719984 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25093483 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 2888417 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31986451 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 31986451 — Biomarker: CYP17A1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CYP17A1; CYP17; S17AH
Study 31986451 — Biomarker: KCNH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNH2; ERG; ERG1; HERG
Study 27248716 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21347737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12749508 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 23179471 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 21502083 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21502083 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 21502083 — Biomarker: Undetectable plasma HIV RNA
Type: Surrogate Endpoint (SUR)
Study 17848760 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 29359480 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 29359480 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29359480 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 29359480 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 29359480 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24846347 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 15969895 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7955975 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24059134 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21311355 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 17087620 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14687172 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24382338 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24382338 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24382338 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7394133 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23262301 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 22484721 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10472596 — Biomarker: A1CF mRNA
Type: Predictive Biomarker (PRD)
Genes: A1CF; ACF; ASP
Study 31912560 — Biomarker: NTS mRNA
Type: Predictive Biomarker (PRD)
Genes: NTS
Study 30667279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21725374 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 21725374 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 21725374 — Biomarker: TMEM37 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMEM37; PR
Study 21725374 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 21725374 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 16785332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25873045 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 21048039 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22476926 — Biomarker: Growth/differentiation factor 8
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: MSTN; GDF8
Study 22476926 — Biomarker: FSTL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FSTL3; FLRG; UNQ674/PRO1308
Study 22476926 — Biomarker: SMURF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMURF1; KIAA1625
Study 22476926 — Biomarker: FBXO32 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FBXO32
Study 21272713 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 9123923 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1536439 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4038511 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 20099954 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 31836722 — Biomarker: DNAH10 mRNA
Type: Predictive Biomarker (PRD)
Genes: DNAH10; KIAA2017
Study 19408036 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 8789903 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 31326975 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31326975 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31326975 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31326975 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 25822479 — Biomarker: HTR1A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR1A; ADRB2RL1; ADRBRL1
Study 16479196 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 11314565 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 9422294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10768275 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11056332 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 26660938 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23260618 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18650545 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17143127 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17143127 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17143127 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26686313 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26686313 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 24927611 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24927611 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 22880214 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10574478 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8923091 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 29552762 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 22543889 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 16673835 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12722741 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study 8678510 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 31868210 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16091379 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16091379 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7637642 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 2576665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28796934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22290266 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 20642296 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 20642296 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study 20642296 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2310656 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 490882 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25227499 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 23326457 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 18324419 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16224150 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 23180157 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 22333107 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 22333107 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 30115933 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30115933 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30115933 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28655086 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25616438 — Biomarker: Amyloid beta peptide (1-40)
Type: Pharmacodynamic Biomarker (PDY)
Genes: APP; A4; AD1
Study 2977393 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3139337 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 20926529 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19365011 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11264907 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9146855 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7711007 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 30538005 — Biomarker: DDAH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDAH2; DDAH; G6A; NG30
Study 25439692 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 25439692 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 23044290 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1310103 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 31479804 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 29266675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12474066 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 22433304 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17014428 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 17014428 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 17014428 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 17014428 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 8724378 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8724378 — Biomarker: Interleukin 1 alpha
Type: Safety Biomarker (SAF)
Genes: IL1A; IL1F1
Study 8724378 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8724378 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3927062 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 29317275 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28137501 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25511449 — Biomarker: POLD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: POLD1; POLD
Study 21627406 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19141980 — Biomarker: BANF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BANF1; BAF; BCRG1
Study 12943180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12943180 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25362247 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 12482554 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 10839588 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9316528 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2883060 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 30384149 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 27287207 — Biomarker: SPR mRNA
Type: Predictive Biomarker (PRD)
Genes: SPR
Study 23323329 — Biomarker: IDUA mRNA
Type: Predictive Biomarker (PRD)
Genes: IDUA
Study 16324360 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16324360 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 16324360 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 16324360 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 16324360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9502350 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8018759 — Biomarker: PNN mRNA
Type: Predictive Biomarker (PRD)
Genes: PNN; DRS; MEMA
Study 11739866 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22364141 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 22364141 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22364141 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28711708 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 28711708 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 28711708 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26239086 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 22447014 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19687338 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9772139 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 603844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30990549 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19649649 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 19649649 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 17623719 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25546032 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21435203 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17276712 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 17276712 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 10954759 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10954759 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25262788 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 25262788 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 21190450 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 23982674 — Biomarker: HLF mRNA
Type: Predictive Biomarker (PRD)
Genes: HLF
Study 3134468 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 3134468 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3288695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25244801 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23730989 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16309554 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 11093285 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 29732549 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 24297950 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22459771 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 20201749 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20201749 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20201749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10334442 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25968966 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 23292288 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 20192950 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 10580184 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8334889 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 8334889 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18562131 — Biomarker: TPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH1; TPH; TPRH; TRPH
Study 18562131 — Biomarker: HTR1A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR1A; ADRB2RL1; ADRBRL1
Study 16202353 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29691526 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 11848259 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11848259 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3122349 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 22623266 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 22623266 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 16631000 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 11304054 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)