AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 16234763 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7771420 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9972406 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3130890 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 26239735 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18579392 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 10819253 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 8894262 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8894262 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25540062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17469162 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 11252048 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 8277200 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 2470865 — Biomarker: BLM mRNA
Type: Predictive Biomarker (PRD)
Genes: BLM; RECQ2; RECQL3
Study 23154592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12671885 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 2574496 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 23627460 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 21932567 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21932567 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19304668 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19304668 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11738278 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11738278 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11738278 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10481384 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 10481384 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 10481384 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29267221 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 29267221 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 24359313 — Biomarker: SPN mRNA
Type: Predictive Biomarker (PRD)
Genes: SPN; CD43
Study 16085504 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 27001425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22739396 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16950591 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15616079 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31259883 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 31259883 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 22855599 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 22855599 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 22855599 — Biomarker: DNMT3A mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMT3A
Study 19470925 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 19470925 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 19470925 — Biomarker: NR1I2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1I2; PXR
Study 19470925 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 19470925 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 19470925 — Biomarker: ERCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC2; XPD; XPDC
Study 27940458 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20454974 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20454974 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 18410952 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18410952 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 6649055 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29880546 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 29880546 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29880546 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20435865 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27513155 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8868037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1380024 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22178576 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 2882775 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31060632 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 27363506 — Biomarker: SCN9A mRNA
Type: Predictive Biomarker (PRD)
Genes: SCN9A; NENA
Study 24786948 — Biomarker: GRIK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIK1; GLUR5
Study 16390023 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 11207836 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11207836 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12486429 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9798037 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30763599 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 26884439 — Biomarker: G0S2 mRNA
Type: Predictive Biomarker (PRD)
Genes: G0S2
Study 26884439 — Biomarker: PNPLA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PNPLA2; ATGL; FP17548
Study 26884439 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26884439 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25526951 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 19196819 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19196819 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16335699 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 16335699 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11740718 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25839137 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 24206457 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2441156 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 31137991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28557655 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 28557655 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 17100757 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9383502 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 23075398 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16300696 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8554498 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31453982 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 24755888 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 14990394 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9064950 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1473306 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26561047 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 24451613 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15465887 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8072815 — Biomarker: DPT mRNA
Type: Predictive Biomarker (PRD)
Genes: DPT
Study 15779502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25794163 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25794163 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 25794163 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 11930695 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 11930695 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 2853091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29880292 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29880292 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 29880292 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 24200275 — Biomarker: EMB mRNA
Type: Predictive Biomarker (PRD)
Genes: EMB
Study 21169471 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17196057 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 17196057 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 17196057 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17196057 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8957034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8957034 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22446739 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 25351652 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23669281 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17971666 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 30426166 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 28796888 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 7625114 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 7625114 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31464642 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20170948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20170948 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12200762 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12200762 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25110231 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 18068514 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 18068514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18068514 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18068514 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 916947 — Biomarker: Argininosuccinate synthase
Type: Safety Biomarker (SAF)
Genes: ASS1; ASS
Study 18260939 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18260939 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 16231621 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16231621 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12116339 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9987705 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 2187981 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 18756880 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 8786174 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 30972712 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 24293332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16301237 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 9816887 — Biomarker: RAPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPH1; ALS2CR18; ALS2CR9; KIAA1681; LPD; PREL2; RMO1
Study 31043161 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31043161 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31043161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27384376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23981814 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 23981814 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21254162 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21254162 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12040766 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9701417 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7838917 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 21494635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3033180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29923305 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12104065 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12104065 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10588465 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1673616 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29260292 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 22090672 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18477130 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18477130 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7631329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7631329 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29596010 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 28049139 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 28049139 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28049139 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 28049139 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20689466 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9519749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9519749 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1893304 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25645091 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25645091 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25645091 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 23539907 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20931329 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 20931329 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 16980161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10774967 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29316164 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25622626 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 25622626 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23310938 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8801446 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1430701 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 30720538 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30720538 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 30720538 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30720538 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 30720538 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 30720538 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 2161692 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2161692 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 23889806 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 21827773 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21827773 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9715310 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 25719441 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 25719441 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 25719441 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 24615500 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24615500 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19670432 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9935128 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 27761984 — Biomarker: OMG mRNA
Type: Predictive Biomarker (PRD)
Genes: OMG; OMGP
Study 24512486 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 24512486 — Biomarker: SSTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SSTR1
Study 19346521 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15531660 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 11809123 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24812287 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23324897 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23324897 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23324897 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17152732 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17152732 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 17152732 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14747052 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10694774 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15714177 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15714177 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 12890859 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 11050579 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 31746742 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24759125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21805307 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 20080837 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20080837 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8417049 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 12631089 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 28193231 — Biomarker: Osteopontin
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SPP1; BNSP; OPN; PSEC0156
Study 28193231 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19489488 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31880795 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 25050986 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS