AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 14593356 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11001866 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 22609079 — Biomarker: ARAF mRNA
Type: Predictive Biomarker (PRD)
Genes: ARAF; ARAF1; PKS; PKS2
Study 15938034 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12131781 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 12131781 — Biomarker: CCKAR
Type: Safety Biomarker (SAF)
Study 2352788 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 484262 — Biomarker: KCNN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNN1; SK
Study 31309627 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 28412590 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 9543282 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 9543282 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8297217 — Biomarker: DMTN mRNA
Type: Predictive Biomarker (PRD)
Genes: DMTN; DMT; EPB49
Study 10867212 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9100583 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9100583 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9100583 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27358418 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12757987 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 8660148 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 7140008 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24030535 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 10773104 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22883401 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18076261 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 11996470 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 7655177 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25742735 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 25742735 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 15579755 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 29388085 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 22342859 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 2245435 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16078955 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10559515 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 8528732 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8528732 — Biomarker: ACTG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACTG1; ACTG
Study 11807724 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 26900640 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25100134 — Biomarker: VHL mRNA
Type: Predictive Biomarker (PRD)
Genes: VHL
Study 25100134 — Biomarker: FLT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT4; VEGFR3
Study 25100134 — Biomarker: Hypoxia-inducible factor 1-alpha
Type: Predictive Biomarker (PRD)
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 25100134 — Biomarker: Carbonic anhydrase IX
Type: Predictive Biomarker (PRD)
Genes: CA9; G250; MN
Study 25100134 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 18254988 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18254988 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26588662 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 26588662 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 19229603 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11913007 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9522325 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9522325 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9522325 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7526050 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24578074 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 1444555 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19508590 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 19508590 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19508590 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15715181 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 11889308 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11889308 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23253948 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 21727662 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 30850876 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26685004 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 28409515 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 22335622 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22335622 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 22335622 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 20823393 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 7850821 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7850821 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 7850821 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 23302012 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 19059939 — Biomarker: CEBPA mRNA
Type: Predictive Biomarker (PRD)
Genes: CEBPA; CEBP
Study 19059939 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 19059939 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12510813 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7994822 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7994822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31991203 — Biomarker: MMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP2; CLG4A
Study 31991203 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 31991203 — Biomarker: APOA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOA1
Study 31991203 — Biomarker: APOC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOC1
Study 31991203 — Biomarker: APOB mRNA
Type: Predictive Biomarker (PRD)
Genes: APOB
Study 31991203 — Biomarker: APOD mRNA
Type: Predictive Biomarker (PRD)
Genes: APOD
Study 31991203 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 31991203 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 22457321 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 10068868 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 10068868 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 10068868 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 10068868 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 7640325 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 7640325 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 2627388 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 793680 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26075752 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26075752 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10996350 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9313629 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23427388 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 23427388 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18720692 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29396097 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27366132 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24930580 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 24930580 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 24930580 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 24930580 — Biomarker: MAOA mRNA
Type: Predictive Biomarker (PRD)
Genes: MAOA
Study 24930580 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study 24930580 — Biomarker: GRIK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIK3; GLUR7
Study 11228177 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 11228177 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 7931476 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20496733 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20496733 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 18005471 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 18005471 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28403798 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15741734 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15741734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1720488 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6754634 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27321490 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 25147070 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7699528 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31786114 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18306372 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 15653024 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21146687 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 11149435 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11149435 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 15784802 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 779006 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19180896 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 7959572 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 23595590 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19535421 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 26299226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16476160 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1996926 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6352280 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 31146774 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 17848834 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11855664 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 30458684 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 16968802 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18455656 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18455656 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14509156 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 14509156 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 9612329 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9612329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3191000 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22880108 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 22880108 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 19249998 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 11966951 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9497918 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 9497918 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 8097170 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 28281457 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23717490 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23717490 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 21389841 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8661976 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 8661976 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31824142 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31824142 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 31824142 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25855073 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25855073 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23980084 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21725579 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 16362400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11055474 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31581295 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 24446022 — Biomarker: AHSP mRNA
Type: Predictive Biomarker (PRD)
Genes: AHSP; EDRF; ERAF
Study 10686664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31140540 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 22954919 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 22954919 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12401757 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1613829 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 6089540 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6089540 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23006657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17389624 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25197015 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 22458821 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15743397 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 335225 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22684652 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15174894 — Biomarker: LTB mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB; TNFC; TNFSF3
Study 15174894 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15174894 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 8507346 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26546591 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9034286 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26832658 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26832658 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12374899 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31253112 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17224860 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 11686419 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 7943789 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7943789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3062257 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 30237584 — Biomarker: MSX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MSX2; HOX8
Study 30237584 — Biomarker: LMNTD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LMNTD1; IFLTD1
Study 30237584 — Biomarker: PTPRD mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRD
Study 23453465 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20034685 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15479482 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10976977 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 9302444 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3540229 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3540229 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27312945 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 27312945 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24954162 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24954162 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 24954162 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 20550650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20550650 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15953008 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12748666 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 7644852 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25605528 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23490237 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 8435994 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30137217 — Biomarker: VCAM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VCAM1
Study 30137217 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 10583454 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 10583454 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 31589553 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31171523 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 16087986 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31934993 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 31934993 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 23704673 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 14990632 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 10619583 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)