AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 29911741 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29139301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20453546 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 8740798 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21795458 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19464414 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2645845 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28450262 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 19958541 — Biomarker: SP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP3
Study 23010962 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12355200 — Biomarker: LYST mRNA
Type: Predictive Biomarker (PRD)
Genes: LYST; CHS; CHS1
Study 2229278 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 31926846 — Biomarker: KCNT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNT1; KIAA1422
Study 28963455 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21385401 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14871466 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7970234 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 24625415 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 31323662 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 25918933 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 25918933 — Biomarker: c-Jun N-terminal kinase
Type: Safety Biomarker (SAF)
Study 1355923 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17540991 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 17540991 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17540991 — Biomarker: Complement C4
Type: Monitoring Biomarker (MOI)
Study 11844821 — Biomarker: Dihydrothymine dehydrogenase
Type: Safety Biomarker (SAF)
Genes: DPYD
Study 1691416 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10713313 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10713313 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 27594841 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 15792815 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11865276 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 11257272 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 11367647 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28536866 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 26673577 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 23780578 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27502729 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27502729 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 22895449 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 19211712 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19211712 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 15895882 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12703866 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8704237 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 30953836 — Biomarker: SIGLEC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIGLEC1; SN
Study 24936937 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24936937 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 24936937 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 19819118 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11093007 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 22561658 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22561658 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 22561658 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 10392984 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9836062 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23559220 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11098244 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 11098244 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 11098244 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 1768820 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27912940 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1723461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30422259 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23950601 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23950601 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23950601 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19647431 — Biomarker: SERPINB6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINB6; PI6; PTI
Study 8725414 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 19907100 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17115015 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 9500318 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9500318 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 8961972 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30048858 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22652556 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 15879923 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28665556 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 11994058 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 17586596 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 2745390 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 20202971 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 16791665 — Biomarker: CARD16 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARD16; COP; COP1
Study 20002085 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 20002085 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 29421687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23969907 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 11498721 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8814 — Biomarker: CPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPZ
Study 24259042 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19571282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14769732 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 14769732 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 14769732 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 28247635 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 10601537 — Biomarker: RRAD mRNA
Type: Predictive Biomarker (PRD)
Genes: RRAD; RAD
Study 7851545 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 7851545 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 7851545 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 21544980 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 21544980 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 21544980 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17446439 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17446439 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11205963 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11205963 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26490089 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22653220 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9056614 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9056614 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30197313 — Biomarker: CLPB mRNA
Type: Predictive Biomarker (PRD)
Genes: CLPB; HSP78; SKD3
Study 12860578 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12860578 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12860578 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10375935 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 10375935 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 30307410 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 20825615 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17879531 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26016870 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23436260 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17293085 — Biomarker: CPD mRNA
Type: Predictive Biomarker (PRD)
Genes: CPD
Study 16990657 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 29402762 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27609408 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 22234043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18086760 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 2159694 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29768119 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 16320790 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 29455482 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 25563584 — Biomarker: FGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF2; FGFB
Study 25563584 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1799922 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1799922 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6274473 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 6274473 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26736024 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 21917440 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15198477 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15198477 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 30138384 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27009936 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12771603 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 12771603 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12771603 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1316401 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26613768 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26613768 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26613768 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26613768 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21427425 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18834717 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 17555947 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7936513 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26337539 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 26337539 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26337539 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21138462 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 15760313 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study 11962564 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27553181 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18549330 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1954075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22896665 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12372673 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9822045 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8017470 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8017470 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31555976 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31555976 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16469323 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16469323 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 20601897 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 20601897 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31924332 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 23731996 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 8004841 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20592644 — Biomarker: ACTG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACTG1; ACTG
Study 15913800 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 15913800 — Biomarker: Th2 cell
Type: Safety Biomarker (SAF)
Study 9926970 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7489963 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 7489963 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 17372126 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25388643 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 22381051 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22381051 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6794083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15476485 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 2565995 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23921307 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23921307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23921307 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10434906 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 8140873 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 3555604 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 3555604 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 21478817 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2856785 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2856785 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 30650326 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 19175372 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 12375395 — Biomarker: ACSL4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACSL4; ACS4; FACL4; LACS4
Study 8605054 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 813411 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27333986 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19380449 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 19380449 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 19380449 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 17050503 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14524646 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14524646 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 14524646 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 14524646 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9066355 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 9066355 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27399197 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20964867 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12584032 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7687716 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 7687716 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27285349 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27285349 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 18243665 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC
Study 18243665 — Biomarker: ADAM11 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ADAM11; MDC
Study 18243665 — Biomarker: CCL22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 18243665 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 18243665 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 18243665 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 1518433 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 1518433 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 30007559 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24343353 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 8869897 — Biomarker: SLAMF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLAMF1; SLAM
Study 6655288 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 29066841 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29066841 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21791651 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4