AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT03115853 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study NCT01243359 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT01243359 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00037817 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT04621214 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT04621214 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study NCT04056195 — Biomarker: SKI mRNA
Type: Predictive Biomarker (PRD)
Genes: SKI
Study NCT04056195 — Biomarker: SYK mRNA
Type: Predictive Biomarker (PRD)
Genes: SYK
Study NCT01524627 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study NCT03777969 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study NCT03777969 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT00321958 — Biomarker: HGD mRNA
Type: Predictive Biomarker (PRD)
Genes: HGD; HGO
Study NCT03525184 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01894269 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT02826356 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT05504629 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02419118 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study NCT03381482 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03752190 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT02184221 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT02980146 — Biomarker: KLRD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRD1; CD94
Study NCT02980146 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study NCT01247090 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study NCT00368264 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00264641 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study NCT02783040 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT02783040 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study NCT02783040 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT03801564 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT02143908 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study NCT03642392 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03772847 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03772847 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03662984 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT03662984 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study NCT03662984 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT03663127 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT03663127 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02227173 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study NCT04004442 — Biomarker: AXL mRNA
Type: Predictive Biomarker (PRD)
Genes: AXL; UFO
Study NCT02179762 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04693104 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT03817333 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study NCT01218100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02178813 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00932620 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03068416 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT00694096 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT00006294 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT00006294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01268111 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study NCT01430507 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01027481 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01027481 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT00359333 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT02337972 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03239470 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT01748253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04516499 — Biomarker: RTN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RTN1; NSP
Study NCT00889954 — Biomarker: TGFB1
Type: Safety Biomarker (SAF)
Genes: CED; TGFbeta
Study NCT00889954 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03238911 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT00079924 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT05172453 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT00000429 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT05256121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02220023 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT02220023 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study NCT01872260 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study NCT01872260 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study NCT00983515 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT01217970 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01757626 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT04200807 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04371640 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT00644904 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study NCT01126996 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study NCT02795559 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT02745782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01510015 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study NCT01245738 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01245738 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04627181 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT04046315 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study NCT01229072 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study NCT03503903 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT04384445 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT03935633 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT01212718 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study NCT03818165 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study NCT03451565 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01907828 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03444974 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT03580642 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03317431 — Biomarker: DRD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD1
Study NCT03317431 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study NCT03773133 — Biomarker: SSTR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SSTR2
Study NCT01625455 — Biomarker: TACR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TACR1; NK1R; TAC1R
Study NCT03384121 — Biomarker: CYP24A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP24A1; CYP24
Study NCT03384121 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT01455012 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04305795 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04305795 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03022292 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01812200 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study NCT01812200 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT03150576 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study NCT03732326 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02665416 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study NCT02665416 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03872427 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study NCT03872427 — Biomarker: Nuclear factor erythroid 2-related factor 2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: NFE2L2; NRF2
Study NCT03872427 — Biomarker: Serine/threonine-protein kinase STK11
Type: Safety Biomarker (SAF)
Genes: STK11
Study NCT01499888 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01538862 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study NCT01672476 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00454168 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT02469116 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT01750580 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study NCT00005631 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT00344773 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00344773 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT01884610 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study NCT02093598 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study NCT02093598 — Biomarker: BAD mRNA
Type: Predictive Biomarker (PRD)
Genes: BAD; BBC6; BCL2L8
Study NCT02093598 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study NCT02093598 — Biomarker: CTNNB1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CTNNB1; CTNNB; OK/SW-cl.35; PRO2286
Study NCT02093598 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study NCT01628900 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study NCT01697072 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT03410576 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study NCT03410576 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study NCT01755923 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01041924 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01388075 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study NCT04383561 — Biomarker: Leucine-rich alpha-2-glycoprotein
Type: Predictive Biomarker (PRD)
Genes: LRG1; LRG
Study NCT04383561 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00197145 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study NCT02147223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04805203 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT01878201 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03375541 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study NCT02684227 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study NCT01855295 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01855295 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT01855295 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT03594097 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03594097 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03594097 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03594097 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03795207 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03795207 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01023087 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT00843921 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study NCT00971347 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02018458 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02694146 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT01718756 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01564303 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study NCT01450410 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study NCT02032147 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study NCT02885870 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study NCT00196586 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT02233010 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study NCT02233010 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT03294135 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT00001893 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03805022 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study NCT01840293 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01840293 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT01840293 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03782428 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00058526 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03539835 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT05261867 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT02011620 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT04732975 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00806884 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT02202447 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03833089 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study NCT02311569 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study NCT04116918 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03364296 — Biomarker: PRDX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRDX1; PAGA; PAGB; TDPX2
Study NCT01852448 — Biomarker: TCF7L2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCF7L2; TCF4
Study NCT03774940 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study NCT03774940 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT03317171 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study NCT01274624 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT02086942 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study NCT05723016 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT00736801 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT00736801 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT02052921 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study NCT02180334 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT02180334 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT03025828 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00850395 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study NCT02361255 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study NCT02361255 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study NCT02739269 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT01914224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01658137 — Biomarker: CDKN2B-AS1
Type: Predictive Biomarker (PRD)
Study NCT01658137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02822131 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT02822131 — Biomarker: SLC12A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC12A3; NCC; TSC
Study NCT01068509 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study NCT00531076 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03647111 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT01173029 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT01341886 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study NCT04716023 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT02519712 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT04397809 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study NCT04397809 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02046850 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT00340600 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study NCT02523768 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study NCT06427278 — Biomarker: HMGA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: HMGA2; HMGIC
Study NCT06427278 — Biomarker: miR-143
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR143
Study NCT02479581 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study NCT04424056 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04424056 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT04424056 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT01395329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00525824 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)