AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 21159432 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9389779 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24850107 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21226953 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14526151 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1483490 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31382524 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26119561 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 22747752 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 22747752 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22747752 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 22747752 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31039663 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31039663 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31039663 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28468648 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 26052700 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11791759 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7730872 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28467729 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9316823 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 28723587 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25465324 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 18799723 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 20589696 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17549054 — Biomarker: ADAMTS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 17549054 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 9075448 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8445289 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 25464511 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 10810461 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 1739172 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 1739172 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 30130674 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18727656 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 16198658 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 16198658 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 16198658 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 16198658 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 16198658 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 28758155 — Biomarker: APOL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOL1; APOL
Study 15697105 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15697105 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12172440 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 7577315 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31058457 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8623963 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28822828 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26720458 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 20048271 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20048271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31234840 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29217757 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21814293 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19339405 — Biomarker: SSB mRNA
Type: Predictive Biomarker (PRD)
Genes: SSB
Study 21795297 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21795297 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11595381 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study 11595381 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16333028 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9504437 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29187388 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29187388 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25194428 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25194428 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22402823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11119744 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31914443 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 24595228 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24595228 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 24595228 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19939196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1836824 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1836824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20530296 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20530296 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18411833 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 15599116 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 21432597 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 9591449 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 9591449 — Biomarker: Complement C4
Type: Monitoring Biomarker (MOI)
Study 23059810 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19875685 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31102988 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24130072 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22108485 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16310924 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9061804 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 29742109 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 23428336 — Biomarker: L-acetylcarnitine
Type: Safety Biomarker (SAF)
Study 16937274 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9083616 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 23031471 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 19614803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9660521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6945041 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30124941 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22097175 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15125032 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6130244 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23204157 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23204157 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12850128 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 31049566 — Biomarker: TCF7L2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCF7L2; TCF4
Study 29500454 — Biomarker: PNPLA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PNPLA2; ATGL; FP17548
Study 23805175 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 12660520 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29284427 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29284427 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 25706090 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 25706090 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 20378644 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 18777992 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 9431711 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 25980298 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16898488 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8780660 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1621675 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1621675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29894613 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 20838357 — Biomarker: MGP mRNA
Type: Predictive Biomarker (PRD)
Genes: MGP; MGLAP; GIG36
Study 7662220 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7662220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7662220 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21851905 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 28654365 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 28654365 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 11773150 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 30519766 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30519766 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27798417 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19038356 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16886330 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 8384097 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22700860 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11464446 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7735153 — Biomarker: UBXN11 mRNA
Type: Predictive Biomarker (PRD)
Genes: UBXN11; SOC; UBXD5; PP2243
Study 29410606 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11052431 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11052431 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 29611171 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29611171 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 10624069 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28032435 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 22484664 — Biomarker: CA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA1
Study 17659837 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 14764790 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14764790 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14764790 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 14764790 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9105648 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9105648 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31259628 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23719216 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23719216 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29789969 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 21028997 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21028997 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 21028997 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22200382 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 22200382 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 15653117 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15653117 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10554570 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 10580169 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 28545277 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 18493215 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 2874032 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31411963 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 23796235 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8904876 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 28993335 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23681159 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 21440749 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 27749321 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27749321 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26407654 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26407654 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26407654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26407654 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23943839 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 22288485 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 12463106 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20708393 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29951886 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29951886 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26246443 — Biomarker: DRD3
Type: Safety Biomarker (SAF)
Study 16554448 — Biomarker: HNMT mRNA
Type: Predictive Biomarker (PRD)
Genes: HNMT
Study 1588379 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 3838405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29072800 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 20205704 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8724043 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30746581 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15256675 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15256675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3036903 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3036903 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 26325644 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26325644 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26325644 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 16504528 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 7912442 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31719527 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19934816 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16467663 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9292585 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8308770 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8308770 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 20399986 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20399986 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6406586 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18048467 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11792411 — Biomarker: PAFAH1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study 27614854 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8840343 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 30424786 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27548026 — Biomarker: PTGS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGS1; COX1
Study 27548026 — Biomarker: HPGD mRNA
Type: Predictive Biomarker (PRD)
Genes: HPGD; PGDH1; SDR36C1
Study 27548026 — Biomarker: PTGER4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGER4; PTGER2
Study 25448495 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25448495 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 25448495 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 19844694 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15878930 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 20585296 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2856779 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21076842 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25468411 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 17038636 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 17038636 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 17645253 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 7595984 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2220621 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)