AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 9284853 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31928523 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31928523 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10955773 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 8694306 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21095484 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30803542 — Biomarker: DNA repair endonuclease XPF
Type: Predictive Biomarker (PRD)
Genes: ERCC4; ERCC11; XPF
Study 24338514 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17518923 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 9704737 — Biomarker: ROPN1L mRNA
Type: Predictive Biomarker (PRD)
Genes: ROPN1L; ASP; RSPH11
Study 2480613 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 18614861 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15747448 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10520081 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10520081 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 12150629 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 7884424 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23506972 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 20629698 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 18714934 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 7723663 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 23347259 — Biomarker: RHD mRNA
Type: Predictive Biomarker (PRD)
Genes: RHD
Study 16923414 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9597417 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 11691520 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2906018 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30545242 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19139427 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 17198089 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17198089 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 17198089 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12140732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22540523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22540523 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22540523 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24453078 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 24453078 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 12804926 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 12804926 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3905064 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 19857542 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 10202575 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 28904053 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 28904053 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16954712 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30045336 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 30045336 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30045336 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23588255 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 20487410 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 1849160 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 16556072 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29458407 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 24064461 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study 8640295 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 29422384 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 23743811 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16508131 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18484901 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12194927 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 7198413 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7198413 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29166256 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 15543326 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9952092 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 25697217 — Biomarker: MGP mRNA
Type: Predictive Biomarker (PRD)
Genes: MGP; MGLAP; GIG36
Study 19125992 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 1465079 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25583761 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 18649055 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18649055 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20160157 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 16583990 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 16583990 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 12131102 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 19617879 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2741218 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 22943577 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21431424 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21431424 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 17598639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29406853 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 25620436 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23725919 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12934464 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12934464 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study 12934464 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 10868643 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10868643 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 10868643 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25538197 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17713346 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 17713346 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 1404502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21095267 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 12892806 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7851597 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 28487444 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23819631 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23819631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21078948 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19506159 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 9660150 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31409158 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31409158 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25961616 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 16397284 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 16397284 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9279217 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29548345 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19846183 — Biomarker: Vascular endothelial cadherin
Type: Safety Biomarker (SAF)
Genes: CDH5
Study 30717779 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 30717779 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20194302 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17536128 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17536128 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17536128 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7752655 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1963691 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 24861389 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 31935109 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 28822516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22027728 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 25719610 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25719610 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 19208697 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27513367 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 23356247 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23348954 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23348954 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 19004195 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 9483407 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9483407 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 31705874 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14598948 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 14598948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1574972 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2967315 — Biomarker: CEACAM6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CEACAM6; NCA
Study 16978071 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8298198 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8298198 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8298198 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 25215557 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25215557 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22179810 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 22179810 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18022088 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 6364370 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 6364370 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 30057015 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14514570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1394057 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 15680854 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8282352 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3177083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24094693 — Biomarker: KCNQ2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNQ2
Study 10861652 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9144683 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27802427 — Biomarker: High-frequency oscillations
Type: Pharmacodynamic Biomarker (PDY)
Study 2495053 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21162644 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31145699 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19665415 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14964492 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 9797181 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9797181 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22618923 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8749695 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8749695 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 27116645 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27116645 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 27116645 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 10757081 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10757081 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 10757081 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 27038714 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 27038714 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25318892 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 25318892 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 16083533 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 12177656 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 30445611 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25307976 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25307976 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25307976 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25307976 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 19010943 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14764753 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 14764753 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 14764753 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 14764753 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14764753 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 11321143 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 8989254 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 22243943 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 22243943 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19710156 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23186975 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17875305 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 17875305 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11094868 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11094868 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 11094868 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 11094868 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 11094868 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 25621158 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 25621158 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 11588406 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7639807 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 7639807 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31809326 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 24939678 — Biomarker: GCA mRNA
Type: Predictive Biomarker (PRD)
Genes: GCA; GCL
Study 15925816 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 15925816 — Biomarker: Proliferation marker protein Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67
Study 21320366 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21320366 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 19944363 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19944363 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19944363 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 31669047 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6173204 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 31329216 — Biomarker: Major prion protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRNP; ALTPRP; PRIP; PRP
Study 17463301 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 11055475 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3723262 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 24458074 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24458074 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22632452 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 12716484 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 17607437 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 17607437 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 16141440 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25613468 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 18710606 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)