AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24929431 — Biomarker: HNF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: HNF1A; TCF1
Study 17434847 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28408243 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 8989424 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 21102998 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 18203893 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10999156 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25563677 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 24247275 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24247275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24247275 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15187573 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15187573 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10489384 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17337887 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15485475 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 15485475 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 9623632 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 9623632 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9623632 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 24003041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21410294 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 21410294 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 21410294 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 21410294 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12511526 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30653843 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17679559 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 2742942 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 810265 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29223557 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27769209 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20133499 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20133499 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 12641541 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27296663 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 25148255 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 25148255 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 25148255 — Biomarker: CYP4F2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP4F2
Study 17324220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29144805 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 29144805 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 8518408 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30563479 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 30563479 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10589807 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 7060821 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25084280 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25084280 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17887946 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17887946 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21427643 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 17045826 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 17045826 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15266207 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 18929499 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 20210697 — Biomarker: USH1G mRNA
Type: Predictive Biomarker (PRD)
Genes: USH1G; SANS
Study 17620783 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 7042370 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24177001 — Biomarker: LOXL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LOXL2
Study 9655769 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 9655769 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7658819 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2787297 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2787297 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 21701268 — Biomarker: SPAG9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPAG9; HSS; KIAA0516; MAPK8IP4; SYD1; HLC6
Study 21701268 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19798725 — Biomarker: SGCA mRNA
Type: Predictive Biomarker (PRD)
Genes: SGCA; ADL; DAG2
Study 19798725 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19798725 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 17102650 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 15526307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7560695 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study 7560695 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 28946736 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 24135303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17944632 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28433267 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25618125 — Biomarker: CLNK mRNA
Type: Predictive Biomarker (PRD)
Genes: CLNK; MIST
Study 21262931 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 22791944 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 22791944 — Biomarker: Th2 cell
Type: Safety Biomarker (SAF)
Study 22791944 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 17214829 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9748876 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7923515 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31302586 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27595680 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18608712 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12381942 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12381942 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29100778 — Biomarker: SAA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAA1
Study 29100778 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 29100778 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21362275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19920269 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2560684 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28608926 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21649532 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14715848 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 14715848 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9134917 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9134917 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 7950180 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26277548 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18400718 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 12725879 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 1568584 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 3158321 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 3158321 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 3158321 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 3158321 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31822925 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30352583 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24952865 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 8679357 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8679357 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 6344698 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18702848 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 23563245 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 20431530 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 12192104 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 12192104 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 7754939 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26303134 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 26303134 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 17671215 — Biomarker: TNFSF10 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF10; APO2L; TRAIL
Study 17671215 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 17671215 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11973440 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11973440 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28545564 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17449575 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 12154422 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10604523 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10604523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30063723 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30063723 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 30063723 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 30063723 — Biomarker: FLT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT4; VEGFR3
Study 30063723 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30063723 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24938324 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 20368057 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 19337557 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12781159 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 6871083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30115121 — Biomarker: GRIK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIK1; GLUR5
Study 27181886 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22264278 — Biomarker: SLC13A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC13A5; NACT
Study 22264278 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 22264278 — Biomarker: PTGDS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGDS; PDS
Study 19174703 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19174703 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23169292 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23169292 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 23169292 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 10830415 — Biomarker: PAICS mRNA
Type: Predictive Biomarker (PRD)
Genes: PAICS; ADE2; AIRC; PAIS
Study 9014744 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28007665 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 28007665 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 26139733 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15203886 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9479357 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 7931484 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 18716528 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30425104 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24168291 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18050629 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 18312872 — Biomarker: DEFA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DEFA1; DEF1; DEFA2; MRS; DEFA1B
Study 1697914 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28416836 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28416836 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 28416836 — Biomarker: FBXO8 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBXO8; FBS; FBX8; DC10; UNQ1877/PRO4320
Study 28416836 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21316442 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 21316442 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17536871 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 14973517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14973517 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2596737 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 29090352 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29090352 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 16902063 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16902063 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1895677 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 28247026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23972263 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 16730924 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 30562772 — Biomarker: SSB mRNA
Type: Predictive Biomarker (PRD)
Genes: SSB
Study 30562772 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 22910317 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22910317 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 22910317 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16138418 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16138418 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11873071 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11873071 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 27841974 — Biomarker: Tetranectin
Type: Predictive Biomarker (PRD)
Genes: CLEC3B; TNA
Study 25072098 — Biomarker: CHRNA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA5; NACHRA5
Study 25072098 — Biomarker: CHRNA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNA3; NACHRA3
Study 25072098 — Biomarker: CHRNB4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHRNB4
Study 25072098 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 23152839 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15730171 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11889394 — Biomarker: PTPRF mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRF; LAR
Study 24909481 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12037739 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 10562483 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31343603 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23797054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19699855 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19699855 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8998091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3553493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24464974 — Biomarker: TNS4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNS4; CTEN; PP14434
Study 24464974 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15754390 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 6192894 — Biomarker: COPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COPB1; COPB; MSTP026
Study 31958178 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 31958178 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 24722261 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23673286 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 23673286 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 23673286 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 23673286 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30758896 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 11382895 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 4006345 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 4006345 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27612562 — Biomarker: COPE mRNA
Type: Predictive Biomarker (PRD)
Genes: COPE
Study 23316080 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21211331 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21211331 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 31474546 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study 24334318 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24334318 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 20104986 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15986591 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 26134993 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 1670113 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 21862748 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10981543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)