AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 10482259 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29374233 — Biomarker: TERT mRNA
Type: Predictive Biomarker (PRD)
Genes: TERT; EST2; TCS1; TRT
Study 20518809 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15674510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2227553 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 26043229 — Biomarker: GCKR mRNA
Type: Predictive Biomarker (PRD)
Genes: GCKR
Study 11200732 — Biomarker: DPT mRNA
Type: Predictive Biomarker (PRD)
Genes: DPT
Study 19672742 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19672742 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31793630 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29056106 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17470687 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17470687 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12905875 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3135784 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25050594 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 16402915 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16402915 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16402915 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 15673102 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23136195 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 23136195 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 21756757 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23132825 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16458316 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 1329920 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 20078813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16294263 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 27232884 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27232884 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27232884 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27232884 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 23997107 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8806342 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31056784 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29961059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29961059 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16988198 — Biomarker: Nasal potential difference
Type: Pharmacodynamic Biomarker (PDY)
Study 2244710 — Biomarker: AMN mRNA
Type: Predictive Biomarker (PRD)
Genes: AMN; UNQ513/PRO1028
Study 2244710 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31129917 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19464613 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 19464613 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11566639 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 8154486 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18583464 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 18583464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18583464 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11802244 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 28992192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21845341 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21845341 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8894937 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2003079 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6152120 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 25461390 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 9250136 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 9250136 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9250136 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 26630989 — Biomarker: ROCK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROCK2; KIAA0619
Study 18427001 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 18427001 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 12859445 — Biomarker: SCGB3A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SCGB3A2; PNSP1; UGRP1; UNQ566/PRO1128
Study 24588936 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 17945530 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17945530 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 2199131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2278166 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2278166 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2278166 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2278166 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 23541376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23541376 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2059393 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2059393 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26043560 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 26043560 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23690237 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21593661 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 21593661 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21593661 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16945057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15261317 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3159547 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 3159547 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3159547 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3159547 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 29043412 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 23279860 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 16141377 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 29020193 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29020193 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26602006 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 26602006 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26602006 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 26602006 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23529570 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 10965198 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 28698243 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 18637718 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 10928228 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9295593 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20653798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24858921 — Biomarker: WWTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WWTR1; TAZ
Study 24858921 — Biomarker: TMEM97 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMEM97; MAC30; S2R
Study 20179751 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20179751 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 16052109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30422368 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 24502859 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 20829497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15843081 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8270459 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 25659979 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 25659979 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24120179 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17085376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10916100 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10916100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10916100 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 1325762 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1325762 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 6363096 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6363096 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30885955 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 30885955 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 30885955 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21253373 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 21253373 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21253373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9651908 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25786050 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 23924790 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21133742 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11895067 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31787150 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31787150 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 25241271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15075878 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 9394313 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9394313 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9394313 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 27737692 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 23497109 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 17426001 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9208360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31990936 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 21703806 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 1649497 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 1649497 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 28595464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25281894 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25281894 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25281894 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 10999783 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 8852910 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 30439316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18345549 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 3100871 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 27936214 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 15896421 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30759089 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 30759089 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 26936519 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26936519 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22144699 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8866899 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31120518 — Biomarker: IGFBP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP6; IBP6
Study 31120518 — Biomarker: GPC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPC3; OCI5
Study 27859252 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 21250901 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11577946 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 9698961 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 30835573 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30835573 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26081765 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18359280 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18359280 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11303724 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 2572260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21843921 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21843921 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 31142254 — Biomarker: COG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: COG2; LDLC
Study 31142254 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31142254 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28489465 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26517214 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 26517214 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study 21084763 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 21084763 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 21084763 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 3034757 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 3034757 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15555666 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9131679 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 8198026 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31799981 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31799981 — Biomarker: GPX4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPX4
Study 29368212 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 29368212 — Biomarker: MLH3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MLH3
Study 29368212 — Biomarker: RAD21 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAD21; HR21; KIAA0078; NXP1; SCC1
Study 29368212 — Biomarker: SMC4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMC4; CAPC; SMC4L1
Study 24979303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24979303 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22248497 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17395393 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17395393 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9891943 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 26046730 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23044498 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15863204 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study 10726111 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10726111 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 10726111 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 14733779 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11282177 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23181790 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23181790 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 23181790 — Biomarker: CXCR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR3; GPR9
Study 23181790 — Biomarker: CCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR4; CMKBR4
Study 23181790 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 15707951 — Biomarker: NOS1AP mRNA
Type: Predictive Biomarker (PRD)
Genes: NOS1AP; CAPON; KIAA0464
Study 10589806 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 1755555 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28560655 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 8023998 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 28791521 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 24119989 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20555276 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 2069490 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 27179731 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 15817595 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15817595 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12226607 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 10374174 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 16740843 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8302395 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8302395 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 8302395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21558457 — Biomarker: SLC38A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 19616987 — Biomarker: ADORA2A
Type: Safety Biomarker (SAF)
Genes: RDC8
Study 23866835 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23866835 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21359104 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30937304 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study 25597529 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 23438483 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2