AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 11913610 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9422174 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2137344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6962371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29737226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21191076 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 21191076 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 16201128 — Biomarker: FAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FAT1; CDHF7; FAT
Study 16201128 — Biomarker: FAT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FAT2; CDHF8; KIAA0811; MEGF1
Study 30298667 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 27742802 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 27742802 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 27742802 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 27742802 — Biomarker: NRF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRF1
Study 27742802 — Biomarker: Nuclear factor erythroid 2-related factor 2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: NFE2L2; NRF2
Study 27742802 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 8746201 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 8746201 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 8746201 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 1675370 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 31781230 — Biomarker: SBDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SBDS; CGI-97
Study 20337988 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 18034853 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 10099064 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10099064 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1057909 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15499298 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 11433707 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 10353472 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10353472 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 2213262 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 28580602 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27559351 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 21861032 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 26650380 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29442239 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16609019 — Biomarker: HOXB13 mRNA
Type: Predictive Biomarker (PRD)
Genes: HOXB13
Study 16609019 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8808722 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29753474 — Biomarker: CYP27B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 29753474 — Biomarker: CYP24A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP24A1; CYP24
Study 29753474 — Biomarker: T-cell specific protein RANTES
Type: Safety Biomarker (SAF)
Genes: CCL5; D17S136E; SCYA5
Study 26836244 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21486162 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 21486162 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 15037821 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15037821 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15037821 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31930891 — Biomarker: PGR mRNA
Type: Predictive Biomarker (PRD)
Genes: PGR; NR3C3
Study 29934198 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23884638 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20102859 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18635470 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10472359 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 31401675 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31401675 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 27586548 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22327091 — Biomarker: FMOD mRNA
Type: Predictive Biomarker (PRD)
Genes: FMOD; FM; SLRR2E
Study 20935080 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20935080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11833749 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 10517170 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 12480784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2697240 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27588891 — Biomarker: PTN mRNA
Type: Predictive Biomarker (PRD)
Genes: PTN; HBNF1; NEGF1
Study 16427211 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9402166 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9402166 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 24719063 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 22388466 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10653869 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 28213188 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25862833 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19726290 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 26627641 — Biomarker: C-X-C motif chemokine 11
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 14562564 — Biomarker: CPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPB1; CPB; PCPB
Study 11090726 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9373242 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 9373242 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18550081 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9692843 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 8025393 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31786177 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 26259134 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10680804 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 18794104 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 10475719 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 26704170 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15610695 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15610695 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27858112 — Biomarker: IMPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IMPA1; IMPA
Study 25028999 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 22072362 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20467617 — Biomarker: RRAD mRNA
Type: Predictive Biomarker (PRD)
Genes: RRAD; RAD
Study 3933984 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 18670229 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study 10663912 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 1345049 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7437259 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21235696 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 19491283 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 10474149 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 6993252 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20806430 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 20806430 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18821688 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28699628 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 19377437 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18760145 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 15907416 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 10832659 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 10832659 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 10832659 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10832659 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 10832659 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 31542245 — Biomarker: CDKAL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKAL1
Study 11717611 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 28923291 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 25755093 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23824699 — Biomarker: Chromosome 5q
Type: Predictive Biomarker (PRD)
Study 19637334 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 19637334 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18838533 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18838533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12599047 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27647855 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30659987 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 30659987 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 30659987 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 7208540 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31752977 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 31752977 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 3485203 — Biomarker: TAOK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 30488404 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 24378101 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 28043722 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28043722 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21714711 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 21714711 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10945314 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 3811806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29443653 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29443653 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 27099924 — Biomarker: miR-223
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR223
Study 27099924 — Biomarker: miR-135a
Type: Predictive Biomarker (PRD)
Study 27099924 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27099924 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20378840 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20378840 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15703206 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11783602 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11783602 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 11783602 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9408691 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8381081 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 31629852 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23890931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23890931 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15220698 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7591850 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16326376 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 31769845 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25451384 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23211356 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 19403844 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17005078 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17005078 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 17005078 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 3788835 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30103241 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 23945842 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23945842 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1183355 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26207902 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 23453090 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21946848 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 27717126 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24930512 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21288052 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 2040933 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 30938860 — Biomarker: CLDN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLDN1; CLD1; SEMP1; UNQ481/PRO944
Study 30938860 — Biomarker: MUC12 mRNA
Type: Predictive Biomarker (PRD)
Genes: MUC12; MUC11
Study 30938860 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 25759961 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 25759961 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 7872981 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 7872981 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22177808 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 20831528 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20831528 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18711190 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9861520 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9861520 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23890493 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 21980810 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 11531217 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 31911667 — Biomarker: LIF mRNA
Type: Predictive Biomarker (PRD)
Genes: LIF; HILDA
Study 31911667 — Biomarker: CREG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CREG2
Study 31911667 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 31911667 — Biomarker: CCBE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCBE1; KIAA1983; UNQ1921/PRO4395
Study 31911667 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 29465052 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29465052 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23228348 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23228348 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8718542 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28404769 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22796902 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20028945 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17901959 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 11281233 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 11281233 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 30658649 — Biomarker: CLC mRNA
Type: Predictive Biomarker (PRD)
Genes: CLC; LGALS10; LGALS10A
Study 30658649 — Biomarker: PRSS33 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRSS33
Study 30658649 — Biomarker: FCER1A mRNA
Type: Predictive Biomarker (PRD)
Genes: FCER1A; FCE1A
Study 30658649 — Biomarker: HRH4 mRNA
Type: Predictive Biomarker (PRD)
Genes: HRH4; GPCR105
Study 30658649 — Biomarker: ADORA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADORA3
Study 30658649 — Biomarker: P2RY14 mRNA
Type: Predictive Biomarker (PRD)
Genes: P2RY14; GPR105; KIAA0001
Study 30658649 — Biomarker: ALOX15 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALOX15; LOG15
Study 30658649 — Biomarker: OLIG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OLIG2; BHLHB1; BHLHE19; PRKCBP2; RACK17
Study 30658649 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 19691834 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19691834 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17088909 — Biomarker: TOP2A mRNA
Type: Predictive Biomarker (PRD)
Genes: TOP2A; TOP2
Study 17088909 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9131280 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26874511 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26874511 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26874511 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 19967558 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1058422 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 30390361 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27320184 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27320184 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9196144 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24933196 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24933196 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24933196 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2