AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 22621166 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 20954960 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17388962 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 17388962 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28054262 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 8461219 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 3026294 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3026294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29291887 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29291887 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15781429 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 7073415 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7073415 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29653915 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10197230 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30595565 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 27488472 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 17932136 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20679736 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12212785 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 10099033 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10099033 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7001207 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23467363 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 19843667 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 29258549 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 23550861 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21324167 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9159038 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16429299 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17290061 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 23620949 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 12671829 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12671829 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12671829 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31935026 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 14747042 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9177894 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8263885 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31780023 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 6807081 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 19139851 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19139851 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12841346 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12841346 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21448726 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19195512 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1770473 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29222893 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24523436 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 24523436 — Biomarker: CCL18 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 24523436 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 24523436 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17907107 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 16045858 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8635058 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2127226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22085316 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19088267 — Biomarker: CXCR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR3; GPR9
Study 11528360 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 7522899 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 7522899 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26600645 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6430811 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27161974 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22446170 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 20181810 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20181810 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11715356 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11715356 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 825821 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 31222434 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 25118055 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25118055 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19614805 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12473876 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2366542 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31787055 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 27136962 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 27136962 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 15974642 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 15974642 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 15974642 — Biomarker: CYP2E1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2E1; CYP2E
Study 15974642 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 30810754 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23514733 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19575143 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19575143 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 19575143 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 16466554 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 29273207 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 28329061 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 26161399 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26161399 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21215350 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 9364996 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 3087241 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29356602 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12679832 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20040336 — Biomarker: ABCB4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCB4; MDR3; PGY3
Study 15738932 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12627305 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18344178 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 2364508 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26040978 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 15975182 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21975293 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 20152212 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 12638326 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10226901 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 7042502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23897015 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21991942 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30265153 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27216329 — Biomarker: OSR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OSR1; ODD
Study 17984668 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12390317 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 12390317 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 12390317 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 12390317 — Biomarker: IL16
Type: Safety Biomarker (SAF)
Genes: LCF; IL-16; prIL-16; HsT19289; FLJ42735; FLJ16806
Study 12390317 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 7847530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25877498 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 15015438 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31823130 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 28930490 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 29061183 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29061183 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21263414 — Biomarker: IPP mRNA
Type: Predictive Biomarker (PRD)
Genes: IPP; KLHL27
Study 18823530 — Biomarker: CCND1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND1; BCL1; PRAD1
Study 18823530 — Biomarker: FADD mRNA
Type: Predictive Biomarker (PRD)
Genes: FADD; MORT1; GIG3
Study 18823530 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 2854738 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29483842 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 22374696 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 24633272 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19748665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7742677 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7742677 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24746829 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24746829 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24746829 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15738536 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12118902 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19837764 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 11733394 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 2886716 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12893197 — Biomarker: PLG mRNA
Type: Predictive Biomarker (PRD)
Genes: PLG
Study 8947448 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8947448 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31512717 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20951986 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 27149365 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27149365 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27149365 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15834327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10561813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8722432 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19104360 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 12500172 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 3768242 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30916381 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 11755507 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26743539 — Biomarker: ADAMTS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 26743539 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 26743539 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26743539 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11428735 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9870877 — Biomarker: NOS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOS2; NOS2A
Study 9870877 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8746831 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 8746831 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2184355 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30621702 — Biomarker: LIPG mRNA
Type: Predictive Biomarker (PRD)
Genes: LIPG; UNQ387/PRO719
Study 30621702 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30621702 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25787997 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18001201 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 23831920 — Biomarker: TET2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET2; KIAA1546; Nbla00191
Study 15494466 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9155120 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30872203 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30872203 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30872203 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27767387 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 9466099 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 21717444 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 31130260 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29234808 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 7986398 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26599634 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 23181592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22152013 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22152013 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9438889 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9438889 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7705775 — Biomarker: ACAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAT1; ACAT; MAT
Study 7705775 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11712091 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 8703810 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22089179 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22089179 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22089179 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21429719 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 21429719 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 2651329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28665989 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 19473635 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9028089 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 8500234 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29110281 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 19865092 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19865092 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18262390 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18262390 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18262390 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16169354 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 24387700 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18420395 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 16110022 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 16110022 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 16110022 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 12852722 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12852722 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 7465712 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27567635 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18000962 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 15521899 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11134196 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 28229548 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28229548 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28229548 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24338654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24338654 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 24338654 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 17600040 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12473255 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25845223 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG