AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 16779534 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16779534 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16779534 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16779534 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 8466022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28340145 — Biomarker: NKTR mRNA
Type: Predictive Biomarker (PRD)
Genes: NKTR
Study 20237760 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20237760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3046626 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 3046626 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25804100 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25804100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16220085 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12239424 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 22131290 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 25757757 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23602498 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 23602498 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 10815854 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 8986924 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24161018 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24161018 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2643088 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28222674 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 28222674 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 23031470 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 1827011 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24558079 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 19183164 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7852746 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25374187 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 17981439 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17981439 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2003706 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26685718 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26685718 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20371128 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 12734059 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 10410585 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8533869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8533869 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 31599043 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31651118 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 26147760 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 26147760 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 24295397 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31757473 — Biomarker: S100A12 mRNA
Type: Predictive Biomarker (PRD)
Genes: S100A12
Study 30928020 — Biomarker: Mothers against decapentaplegic homolog 2
Type: Predictive Biomarker (PRD)
Genes: SMAD2; MADH2; MADR2
Study 30928020 — Biomarker: Epithelial cadherin
Type: Predictive Biomarker (PRD)
Genes: CDH1; CDHE; UVO
Study 27384245 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19170908 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 19170908 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 11943448 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11943448 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 25351352 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 25351352 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 22564997 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 8948386 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8948386 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6381884 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 6381884 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 6381884 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29972709 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 11953546 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 803977 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 22537562 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15823628 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 12092978 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 12092978 — Biomarker: MTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 22648841 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10319572 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28062296 — Biomarker: miR-30c
Type: Safety Biomarker (SAF)
Study 22815003 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17156345 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 10612317 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10612317 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15477125 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15477125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15477125 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 11684081 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 22134732 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10989990 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8347328 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29940151 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4042543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31206016 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31206016 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29237386 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 22354457 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 22354457 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 20849620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17761704 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25033789 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 22441301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12165574 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 10064126 — Biomarker: HOPX mRNA
Type: Predictive Biomarker (PRD)
Genes: HOPX; HOD; HOP; LAGY; NECC1; OB1
Study 16038680 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 8901800 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30630804 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26526816 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26526816 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22426327 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 18722511 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18722511 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 18722511 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 16104989 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26139093 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26139093 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26139093 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25311600 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 25311600 — Biomarker: PTPRU mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRU; FMI; PCP2; PTPRO
Study 23986168 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 22614148 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 10025425 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 1323545 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31952456 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 8237937 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 28074489 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 19403504 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30569637 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16428745 — Biomarker: TERF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TERF1; PIN2; TRBF1; TRF; TRF1
Study 16428745 — Biomarker: CLSTN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLSTN1; CS1; KIAA0911
Study 16428745 — Biomarker: CLSTN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLSTN3; CS3; KIAA0726
Study 15325933 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3323262 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30415890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27400949 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 22748821 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 20499017 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11022057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19958132 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19958132 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10408585 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29401297 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27762512 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21294404 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21294404 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17506592 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12093429 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 12093429 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7477146 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2011406 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 2011406 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2011406 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 21824444 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 21824444 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 12111110 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7560251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 436308 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 31274484 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26595300 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 23249429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23249429 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23455721 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21282560 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20306755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7818648 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7818648 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 2453895 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24391139 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20385995 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 20385995 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 20385995 — Biomarker: ERCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC2; XPD; XPDC
Study 20385995 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 20385995 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 2877645 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31747468 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31747468 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31747468 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30251010 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28081351 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28081351 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12427649 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19401662 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16963248 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 14508205 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11025232 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11025232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11264758 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2508791 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 30476131 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19928391 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 12539568 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 8233295 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25575620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23168399 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23168399 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16968913 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 11335737 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8302922 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26360125 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11169027 — Biomarker: CES2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CES2; ICE
Study 18050368 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10852452 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 10852452 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8096389 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27386644 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18374003 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 17409936 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 10834668 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15934285 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 12468782 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 31696504 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19498009 — Biomarker: NOCT mRNA
Type: Predictive Biomarker (PRD)
Genes: NOCT; CCR4; CCRN4L; NOC
Study 14660997 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23926117 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23926117 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3299443 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28326881 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26804247 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23275013 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 10881824 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 29095521 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 2515593 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 27217047 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 17645554 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26233827 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24244339 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 24244339 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 18347653 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 18347653 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 11040231 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7927956 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 395129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28537001 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 27503566 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 17150023 — Biomarker: ID1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ID1; BHLHB24; ID
Study 17150023 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15116260 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 9557622 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2651949 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31537327 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 28757104 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 23639514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19706631 — Biomarker: SPIN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPIN1; OCR; SPIN
Study 10933918 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 1330437 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29158011 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 22115190 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 17139601 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 14971794 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 31987228 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28544610 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 28544610 — Biomarker: PON3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON3
Study 28544610 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 24177170 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 19352324 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF