AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 11772795 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11772795 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7861714 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23679192 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 23679192 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12189360 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 31884472 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 31884472 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 28347654 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 28347654 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21834061 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17461857 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15651747 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15651747 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11269571 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 23687260 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1962596 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28235537 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27923389 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27923389 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24438432 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24438432 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9038445 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 6238910 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17535827 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 24471477 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 29981855 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 25342896 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 20502405 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17478952 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26234554 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8814503 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1348751 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11426091 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11426091 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 11426091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27803392 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 22407197 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1359808 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8681492 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28222251 — Biomarker: LZTS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LZTS2; KIAA1813; LAPSER1
Study 28222251 — Biomarker: NR6A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR6A1; GCNF
Study 30037726 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 30037726 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23414904 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 16331300 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16331300 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14668779 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 10321931 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 27578231 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7572698 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1951552 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31267965 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 28254171 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17095643 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20361330 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19604597 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 23535700 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19880462 — Biomarker: STAR mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAR; STARD1
Study 12525441 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 8948238 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 2415436 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 20052524 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 16032522 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16032522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1925896 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 1925896 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 6918220 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 27422890 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27422890 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31418329 — Biomarker: CXADR mRNA
Type: Predictive Biomarker (PRD)
Genes: CXADR; CAR
Study 27774917 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15613414 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7658178 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2711539 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1148032 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 7933528 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 15601388 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9533929 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 30485516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25264665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16728648 — Biomarker: Leucine-rich repeat kinase 2
Type: Pharmacodynamic Biomarker (PDY)
Genes: LRRK2; PARK8
Study 15237695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22549879 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 10608295 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 23932821 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12959951 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 12833107 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8784750 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 6419709 — Biomarker: Plasma testosterone level
Type: Surrogate Endpoint (SUR)
Study 31158087 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 3541816 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25478537 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16425390 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 8896506 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8896506 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17884510 — Biomarker: MHC class I polypeptide-related sequence A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MICA; PERB11.1
Study 16301343 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11039606 — Biomarker: SPINK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPINK1; PSTI
Study 11039606 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2218733 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28864219 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 23503480 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17014579 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17947609 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17947609 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17947609 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15617993 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 15617993 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 30396622 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 30601336 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 27364375 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24247554 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15181047 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15181047 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11069440 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25494594 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25494594 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15714983 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 11051123 — Biomarker: SULT1A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SULT1A3; STM
Study 3890395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29419569 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 15225828 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 15225828 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26223257 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26223257 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26223257 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 9435323 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27710808 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18679601 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31476911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27077973 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16052058 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 25833063 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25833063 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25833063 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25833063 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 19524243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19524243 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19524243 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19524243 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11371418 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 8289986 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 8289986 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 8289986 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 2060542 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27208982 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26597879 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 26597879 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 22492479 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12206997 — Biomarker: UCP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP3; SLC25A9
Study 10566553 — Biomarker: RAB11FIP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAB11FIP1; RCP
Study 10566553 — Biomarker: VCP mRNA
Type: Predictive Biomarker (PRD)
Genes: VCP
Study 2006653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9708225 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28901116 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 15604328 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 15604328 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15604328 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 31229857 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 28384752 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21297491 — Biomarker: FOXP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 8850405 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 16939523 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15472204 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11576570 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26607848 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24047916 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 24047916 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19515530 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 1327630 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30548692 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29450494 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29450494 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24568917 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9698276 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 9698276 — Biomarker: Complement C4
Type: Monitoring Biomarker (MOI)
Study 23038624 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 23038624 — Biomarker: IGF1R mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1R
Study 23038624 — Biomarker: IGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF2; PP1446
Study 23038624 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 23038624 — Biomarker: IGFBP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP2; BP2; IBP2
Study 23038624 — Biomarker: IGFBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP1; IBP1
Study 19538732 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19538732 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 9056681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23271912 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27522437 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 22442277 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18401017 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 1354494 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26986104 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24176681 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 24176681 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 19015925 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17429539 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11144694 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 8695136 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8695136 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16616662 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16616662 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 10527954 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 10527954 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 8892515 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27681760 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 12032876 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25736101 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7517238 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23291565 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20974593 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 8615394 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 24835247 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24835247 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 24835247 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 9708651 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26869609 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20587587 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7802296 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31226144 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11186094 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 28319589 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21972946 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11726420 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 11726420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27562221 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 15268733 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24859356 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 24859356 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 16157616 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12814712 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28913927 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 24118703 — Biomarker: BOC mRNA
Type: Predictive Biomarker (PRD)
Genes: BOC; UNQ604/PRO1190
Study 18275008 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study 18275008 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 9952266 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 7490153 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20934572 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20934572 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14643272 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10955871 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1