AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 19726350 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17474559 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15911473 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10367023 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7018165 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17448376 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15334509 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8086868 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25526229 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 8778554 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8778554 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 8778554 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 31813866 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24163120 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24163120 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15276659 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 10720128 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8965154 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 31280997 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 31280997 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19549094 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 8737620 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8737620 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 1591369 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 26187183 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24172699 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21645507 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21645507 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15232804 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9517609 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 3191663 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22957013 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 19440168 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 22868247 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 22868247 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 21209062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31258919 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21498100 — Biomarker: COL1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL1A1
Study 21498100 — Biomarker: COL3A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL3A1
Study 16344317 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 10858919 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 11273147 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2455152 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2455152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24682206 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 22075170 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 16189252 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8666320 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23038102 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23038102 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 20437076 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7605984 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 22991267 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 21788629 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14515062 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14515062 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12118746 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12118746 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 12118746 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 12118746 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 31238304 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20813884 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 19481079 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10414879 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24025143 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 17161227 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17161227 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17161227 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2514653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18306243 — Biomarker: ADORA2A
Type: Safety Biomarker (SAF)
Genes: RDC8
Study 11177402 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9638980 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 24206823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24206823 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24206823 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 22309805 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22309805 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 31393082 — Biomarker: Gamma-Histone H2AX
Type: Pharmacodynamic Biomarker (PDY)
Genes: H2AX; H2AFX
Study 19531592 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 19531592 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 19531592 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 17569044 — Biomarker: DCT mRNA
Type: Predictive Biomarker (PRD)
Genes: DCT; TYRP2
Study 15104197 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24804483 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20167686 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 1575169 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1575169 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3918178 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 29872803 — Biomarker: PTPRC
Type: Predictive Biomarker (PRD)
Genes: LCA; T200; GP180
Study 27048871 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 27048871 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 27048871 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 27048871 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 25254489 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25254489 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 21717449 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19521657 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7719245 — Biomarker: ZBTB16 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZBTB16; PLZF; ZNF145
Study 29969577 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25629739 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22899580 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 16396729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8465834 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23017329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17140874 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 11580868 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 8427339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22152750 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19307994 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 16391383 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9711053 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 15893170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22358586 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 20850365 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10331614 — Biomarker: FMR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMR1
Study 10331614 — Biomarker: FMR1
Type: Predictive Biomarker (PRD)
Genes: FMRP; FRAXA; MGC87458
Study 10331614 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2186058 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 2186058 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 11820148 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 11820148 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1695314 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28988307 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study 9718120 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31627408 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31627408 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 31627408 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2537003 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 12477770 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 12477770 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11022927 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8792046 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 22614887 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18841263 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18841263 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18841263 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18841263 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 18841263 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11834429 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31744060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28915283 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 23112214 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 8487239 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29227377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22237061 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22237061 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 1900687 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 21602517 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 21602517 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 19105762 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15470331 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 15470331 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 25904602 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 19087569 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 14626640 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12032039 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 31151363 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 31151363 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31151363 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23021318 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21921285 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 29992150 — Biomarker: TAC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAC1; NKA; NKNA; TAC2
Study 29992150 — Biomarker: MTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 7554782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27992063 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 19463396 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 19463396 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17462482 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 11452676 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9684851 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26431823 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 8362533 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31865333 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31865333 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31865333 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28233944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25957544 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 15956010 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10803472 — Biomarker: HHEX mRNA
Type: Predictive Biomarker (PRD)
Genes: HHEX; HEX; PRH; PRHX
Study 17227905 — Biomarker: XRCC1
Type: Safety Biomarker (SAF)
Genes: RCC
Study 17227905 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 2659995 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 31228618 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 28378301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18930987 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29330660 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31913578 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28169880 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20179652 — Biomarker: F2R mRNA
Type: Predictive Biomarker (PRD)
Genes: F2R; CF2R; PAR1; TR
Study 19907103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10644808 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10644808 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 10644808 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 10644808 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 10644808 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 30770758 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30770758 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30770758 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 30770758 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30770758 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 30770758 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 23945460 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17534246 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 12904193 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7854171 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6801079 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 27001281 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 25494175 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 25510746 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21036778 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19044214 — Biomarker: MYRF mRNA
Type: Predictive Biomarker (PRD)
Genes: MYRF; C11orf9; KIAA0954; MRF
Study 6345421 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22938660 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 22938660 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18441457 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15915547 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10606114 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6114503 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29578880 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23925451 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18335328 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 10500005 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8961085 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8961085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12911553 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31676303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31676303 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31676303 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31676303 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24551257 — Biomarker: AADAC mRNA
Type: Predictive Biomarker (PRD)
Genes: AADAC; DAC
Study 8340055 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23259002 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18183613 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 28029189 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 23441809 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15799932 — Biomarker: RITA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RITA1; C12orf52; RITA; PSEC0043
Study 10902462 — Biomarker: ADAM17 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM17; CSVP; TACE
Study 3799443 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28549637 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18617377 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12729523 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10671303 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8841206 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8841206 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31560700 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25130226 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 19328268 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1