AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 16135167 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 19156155 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19156155 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 14992558 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 10584476 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9097714 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31318392 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 31318392 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 22684565 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22684565 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 22684565 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22684565 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 22684565 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22684565 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22684565 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 22684565 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 15716702 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15716702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22339125 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14977992 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14977992 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 6364778 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 27802843 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22675288 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22675288 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17575467 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31723064 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 31723064 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20214324 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20214324 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 20214324 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20214324 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20214324 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17855709 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 14985171 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 14985171 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11434167 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11434167 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 17122107 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 25604154 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 10652641 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10652641 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 28338504 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21097402 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21097402 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 21097402 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17277593 — Biomarker: MSTN mRNA
Type: Predictive Biomarker (PRD)
Genes: MSTN; GDF8
Study 12374324 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 19085703 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 17134951 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 17134951 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 25335245 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9279213 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 9279213 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29024310 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22462626 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 12050248 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1712266 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1712266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15198882 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15198882 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15198882 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 25194436 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 16223747 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 16223747 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14704844 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 8617412 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8617412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30820661 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 20101007 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8678246 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8678246 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31020900 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28755550 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16267070 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 23307890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18174862 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 16391891 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 24530993 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 22932169 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 11773987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11773987 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11773987 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27277213 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22923289 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 22923289 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18711188 — Biomarker: TLR9
Type: Predictive Biomarker (PRD)
Genes: CD289
Study 15177522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8608658 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31102525 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31131517 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31131517 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31131517 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 31131517 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28240587 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24287217 — Biomarker: PELI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PELI1; PRISM
Study 26859101 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 18948636 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 8731383 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23508601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8273956 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 28720336 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 23899896 — Biomarker: RUNX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX1; AML1; CBFA2
Study 23899896 — Biomarker: FKBP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: FKBP7; FKBP23; UNQ670/PRO1304
Study 15213617 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 28259499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28259499 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 25702618 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21048776 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9215837 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 26603740 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26603740 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24758079 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15935090 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 16303936 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 15807201 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8399641 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28404091 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 28404091 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28404091 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16012762 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9397291 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8394193 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3720571 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28223274 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 28223274 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 28223274 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 28223274 — Biomarker: Homologous recombination deficiency
Type: Predictive Biomarker (PRD)
Study 26604731 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1799929 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24850877 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24850877 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24850877 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9650013 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9650013 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 28065679 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26398281 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 2195580 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28657933 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 25998068 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 21723353 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 9327151 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 1105483 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9230143 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31434935 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23426618 — Biomarker: IRS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRS2
Study 18194401 — Biomarker: HDC mRNA
Type: Predictive Biomarker (PRD)
Genes: HDC
Study 16612399 — Biomarker: PDXP mRNA
Type: Predictive Biomarker (PRD)
Genes: PDXP; CIN; PLP; PLPP
Study 22892751 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 10367619 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10367619 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10367619 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 10367619 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 25867700 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 12028831 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 9566670 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26566091 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23517933 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23517933 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2419693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30365470 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 25376194 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 22589439 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 1738766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1738766 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29069507 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29069507 — Biomarker: CCL22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 19580457 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 11890871 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study 8585220 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31337369 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 21321491 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 29726282 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29726282 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 29726282 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 16082607 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31529385 — Biomarker: SIRPA mRNA
Type: Predictive Biomarker (PRD)
Genes: SIRPA; BIT; MFR; MYD1; PTPNS1; SHPS1; SIRP
Study 26829661 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25103026 — Biomarker: RNPEP mRNA
Type: Predictive Biomarker (PRD)
Genes: RNPEP; APB
Study 16234012 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 2177062 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2177062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 389483 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 17565514 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17565514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26300237 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21569186 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9313755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12515870 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1097344 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20673585 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19463464 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9405029 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9405029 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 9405029 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 26177352 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 8432773 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 18794654 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 20727239 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20727239 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 2486952 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20572767 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 16082528 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1826569 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30997816 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 30997816 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29359722 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24965957 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 23818768 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23818768 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23818768 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23818768 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 23818768 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27802585 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 18199844 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 18199844 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 8627061 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21778151 — Biomarker: CPD mRNA
Type: Predictive Biomarker (PRD)
Genes: CPD
Study 8759084 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 5677210 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25173516 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 351715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29959667 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29959667 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26484463 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15196108 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15196108 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 9649909 — Biomarker: OSBP mRNA
Type: Predictive Biomarker (PRD)
Genes: OSBP; OSBP1
Study 9649909 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8127110 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 26545986 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22475305 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28765644 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 28765644 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 20008239 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 18041162 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23583219 — Biomarker: TNFA
Type: Predictive Biomarker (PRD)
Genes: TNF; TNFSF2; DIF; TNF-alpha
Study 23583219 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)