AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 10834715 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 10834715 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23046320 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 17296571 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19574917 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 19016815 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12795852 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 25964375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23253084 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 23253084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20124885 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16175618 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8610897 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 30700617 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 30700617 — Biomarker: SH3BP5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SH3BP5; SAB
Study 30700617 — Biomarker: GLS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS2; GA
Study 18509324 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1459169 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30577611 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19078834 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15950849 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 12027926 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12027926 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28746558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22013800 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 24975892 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 15287853 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 1583328 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1583328 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 24480867 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19922752 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 25616223 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25616223 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25616223 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25616223 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 25616223 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21221770 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26890171 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20509987 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 18371962 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 31307844 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29218448 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24782426 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 17689737 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 28845523 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 27029704 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27029704 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 23430192 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 18256777 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18256777 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8638521 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1658138 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 31332918 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 29022084 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11113067 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 27604620 — Biomarker: LGI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LGI1; EPT; UNQ775/PRO1569
Study 27604620 — Biomarker: CNTNAP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNTNAP2; CASPR2; KIAA0868
Study 27604620 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 23061642 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10412782 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21402493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17513395 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 17513395 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 7552478 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7040492 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27552000 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21982723 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 12838187 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11113749 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 9007183 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28479233 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 23078573 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 29701038 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 25701449 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 20872709 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9322562 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8228631 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8228631 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8228631 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28737464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11782642 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21257798 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 21257798 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 20016232 — Biomarker: IRF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRF4; MUM1
Study 12874502 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 10898675 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6513774 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6513774 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 30112318 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 20339099 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 9989680 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7369170 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10737167 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3924399 — Biomarker: SHD mRNA
Type: Predictive Biomarker (PRD)
Genes: SHD
Study 3924399 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 31982170 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31982170 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24051496 — Biomarker: HGD mRNA
Type: Predictive Biomarker (PRD)
Genes: HGD; HGO
Study 14613287 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 14613287 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7060034 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 30715732 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 30085138 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 27538799 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 9003882 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18936569 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18936569 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 16101168 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 10510925 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 30501868 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 30501868 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 30501868 — Biomarker: BCL6 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 28775182 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study 10333895 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17227715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12409969 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15026868 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21545981 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21545981 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21545981 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19516150 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 12145060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10022399 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 10022399 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 7417123 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23157710 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 23157710 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21372737 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2963525 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11739071 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 14639446 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17698901 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 12771037 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 23320436 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 19145494 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 3894589 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30977393 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 27328954 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 24336385 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 18971523 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18971523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18971523 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10999803 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 31424649 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 31424649 — Biomarker: TP53BP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TP53BP2; ASPP2; BBP
Study 21793378 — Biomarker: AIFM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AIFM1; AIF; PDCD8
Study 21793378 — Biomarker: CASP9
Type: Predictive Biomarker (PRD)
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 12012943 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2194032 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2194032 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27759579 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23599118 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 16445701 — Biomarker: PAG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAG1; CBP; PAG
Study 27738812 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 27738812 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15850466 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 7587975 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29526502 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29526502 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24726098 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20922537 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 20922537 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15752954 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 15752954 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 15752954 — Biomarker: ADCY10 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADCY10; SAC
Study 6522132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20368505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30923094 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 17173959 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study 14739855 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 14739855 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25873729 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 16330117 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16330117 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15053241 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11424113 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11424113 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3551507 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29728364 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25963351 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25963351 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18288935 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16772796 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9160820 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21632497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18326958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31994262 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 29332135 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23936756 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18284434 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 16502177 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8380606 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3490559 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17209786 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17209786 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 10869918 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 10869918 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9375480 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 30226889 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 23161345 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 23161345 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23161345 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 23161345 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 23161345 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 23161345 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 23161345 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 20594781 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9566550 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23697602 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21294998 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17353512 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29101186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31093952 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 9658616 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17166396 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17166396 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 1390605 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29972757 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 23242584 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 23242584 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23242584 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 14574515 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 11737926 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 17671394 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11919305 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11919305 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9949315 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23864006 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 19196673 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19196673 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19196673 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 19196673 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15212355 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 12914551 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 11603418 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1592448 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6370155 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 30288843 — Biomarker: DCC mRNA
Type: Predictive Biomarker (PRD)
Genes: DCC; IGDCC1
Study 25009402 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29846630 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 21178937 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17215848 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1272739 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1