AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 6758743 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31301436 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 24075621 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 31594196 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27418545 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9252738 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 16440115 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11419768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11419768 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23306362 — Biomarker: LTB mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB; TNFC; TNFSF3
Study 23306362 — Biomarker: CTBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CTBS; CTB
Study 21688030 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16615978 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 22494866 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 19398001 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1781822 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7293938 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19641980 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19641980 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8283895 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 8283895 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28393317 — Biomarker: DMTN mRNA
Type: Predictive Biomarker (PRD)
Genes: DMTN; DMT; EPB49
Study 21812820 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 18504447 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12707160 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15878467 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 9616258 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24351495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18469248 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 10437188 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 20581392 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 12657404 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27797674 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27797674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26001289 — Biomarker: ABCC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC1; MRP; MRP1
Study 26001289 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26001289 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 19194127 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27058964 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 22846453 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22846453 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11994561 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 30215460 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22823027 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 22823027 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22823027 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19106322 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15492316 — Biomarker: AGTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study 15492316 — Biomarker: AGTR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AGTR2
Study 15492316 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15492316 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study 23998969 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26360770 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26360770 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11811547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9515998 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7775548 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 24955456 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 24955456 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17140970 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 27310943 — Biomarker: DRD3
Type: Safety Biomarker (SAF)
Study 22033719 — Biomarker: FBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBP1; FBP
Study 15674316 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15674316 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 15674316 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 15674316 — Biomarker: Serum phosphate
Type: Surrogate Endpoint (SUR)
Study 31878810 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 17855483 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 15881863 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12053586 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 12053586 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29499728 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 31362773 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 21404051 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 21404051 — Biomarker: MDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM2
Study 21665421 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 10412777 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10412777 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29282336 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 12736841 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 1939943 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 30918320 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30918320 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30918320 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 788743 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21292602 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16759923 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16759923 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 15099277 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9803197 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30653851 — Biomarker: S100A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: S100A4; CAPL; MTS1
Study 6094104 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6988713 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26924303 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26924303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26924303 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 26924303 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 26924303 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 26506968 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26506968 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21221773 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19369178 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7752863 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 30116543 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22362918 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 17350856 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16298736 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 25741153 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18979719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16984212 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 10969351 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10969351 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8956766 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14642684 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14642684 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 14642684 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22490404 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20602497 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 20108171 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20108171 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20108171 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11926969 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12088811 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31481110 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 26545677 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 18801802 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18801802 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18801802 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18801802 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29696921 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 24718282 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8839667 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 28595367 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24419307 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 12405434 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 10091789 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 22850760 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 22850760 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 1376847 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22449251 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18698234 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 11438563 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 8000218 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 23193009 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21972403 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19928484 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15221928 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 9296944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27577546 — Biomarker: SHANK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SHANK3; KIAA1650; PROSAP2; PSAP2
Study 25240121 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 14504627 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6846212 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6846212 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6846212 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30540689 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 30540689 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 20350641 — Biomarker: SPTB mRNA
Type: Predictive Biomarker (PRD)
Genes: SPTB; SPTB1
Study 12435472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6138934 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2984397 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 2984397 — Biomarker: Complement C4
Type: Monitoring Biomarker (MOI)
Study 24315894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16472379 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 26497960 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 26497960 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 26497960 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 19528562 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19528562 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17151968 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 10338218 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 20538669 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19018915 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7113949 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 7113949 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 30702971 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 30702971 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25872531 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 23645323 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20528697 — Biomarker: MAEA mRNA
Type: Predictive Biomarker (PRD)
Genes: MAEA; EMP; HLC10; PIG5
Study 12867685 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18653575 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28187400 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22527138 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22073889 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 22073889 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 22073889 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22073889 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 22073889 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 22073889 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27509141 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14568963 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14568963 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23261172 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 17582922 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 15044114 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 8597984 — Biomarker: Ataxin-3
Type: Pharmacodynamic Biomarker (PDY)
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 2527536 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15153170 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15153170 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23152584 — Biomarker: CLCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLCN1; CLC1
Study 18614347 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16371154 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 16371154 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12460041 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 1423955 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26550945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15212190 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 24980238 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 24980238 — Biomarker: IFT122 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFT122; SPG; WDR10; WDR140
Study 23756400 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20653494 — Biomarker: MAF mRNA
Type: Predictive Biomarker (PRD)
Genes: MAF
Study 18408938 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9361692 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24856872 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 24856872 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 20963833 — Biomarker: TTN mRNA
Type: Predictive Biomarker (PRD)
Genes: TTN
Study 19549432 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 11568516 — Biomarker: HLF mRNA
Type: Predictive Biomarker (PRD)
Genes: HLF
Study 24980710 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 12783043 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 24716412 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11705489 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 11705489 — Biomarker: KIT
Type: Predictive Biomarker (PRD)
Genes: CD117; SCFR; C-Kit
Study 21545273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21545273 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11583471 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 2643751 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25929392 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 9234826 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30318837 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 16291412 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 16291412 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 12145231 — Biomarker: BAD mRNA
Type: Predictive Biomarker (PRD)
Genes: BAD; BBC6; BCL2L8
Study 10211849 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 7614527 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26220326 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 17366867 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11108723 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6240210 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26823689 — Biomarker: NR3C1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR3C1; GRL
Study 26823689 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7632972 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 2713221 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26797499 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16463664 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 16463664 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12898884 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19