AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 28590358 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 9575677 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9575677 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study 2907823 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26892612 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 26892612 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 20578534 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18234086 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 18234086 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 9170421 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8400752 — Biomarker: EMP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EMP1; B4B; TMP
Study 8400752 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2891369 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23026132 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 16918591 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 27297843 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 23350191 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23350191 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12145072 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10335872 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 10335872 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 7780060 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7780060 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2081012 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14998841 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 27560256 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27560256 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27560256 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27560256 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27755543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3987071 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 30418164 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 15374489 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31755550 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14602740 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14602740 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1361935 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29156378 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 29156378 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23144467 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 23144467 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study 20229018 — Biomarker: HSPA1B mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA1B; HSP72
Study 15757934 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 3127028 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 30610781 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 19717480 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15966880 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 22244160 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22244160 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16022847 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12243438 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 799558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31441836 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31441836 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26055067 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 23075691 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27849355 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 27849355 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 24859364 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 24859364 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 27072796 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 27072796 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 19583673 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29033108 — Biomarker: TTN mRNA
Type: Predictive Biomarker (PRD)
Genes: TTN
Study 29033108 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7511501 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23053269 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 23053269 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9181181 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2994577 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 29956072 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 29985447 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 27018037 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23856575 — Biomarker: Angiopoietin-1
Type: Monitoring Biomarker (MOI)
Genes: ANGPT1; KIAA0003
Study 9366281 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18839777 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8773910 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8773910 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8773910 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 8773910 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 8773910 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 1312854 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31493297 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 31102396 — Biomarker: CXCL13 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL13; BCA1; BLC; SCYB13
Study 20635176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12040140 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 19854960 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 11418255 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20127562 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study 18318082 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 15942467 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22245891 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22245891 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22245891 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22245891 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 11918884 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 22872229 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6463176 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 14984925 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 14984925 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 23990706 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23990706 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16729277 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11343737 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11343737 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 7988783 — Biomarker: TNFRSF10A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 23592479 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28807031 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26331623 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17947500 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17947500 — Biomarker: Pyruvate dehydrogenase kinase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PDK1; PDHK1
Study 12831948 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12831948 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10232311 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1988077 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 1988077 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1988077 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1988077 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2876664 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30054049 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 28662222 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28662222 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 21196894 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 10770187 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8393108 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 18847422 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16635293 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31237044 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 31237044 — Biomarker: E2F1 mRNA
Type: Predictive Biomarker (PRD)
Genes: E2F1; RBBP3
Study 31237044 — Biomarker: PSMD8 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSMD8
Study 31237044 — Biomarker: AXIN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AXIN1; AXIN
Study 31237044 — Biomarker: GAB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAB2; KIAA0571
Study 16875919 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16875919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9177376 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9177376 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9177376 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9177376 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 26559681 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 26559681 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24655701 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24655701 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21088807 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 16372585 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 16372585 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11497156 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 8221579 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 30289006 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29873709 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29873709 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22854402 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 22854402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10476945 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29753661 — Biomarker: MIA mRNA
Type: Predictive Biomarker (PRD)
Genes: MIA
Study 29753661 — Biomarker: CNR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNR1; CNR
Study 26902276 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 26902276 — Biomarker: CXCL1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 26902276 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 25465181 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 23769863 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23769863 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10620000 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8620093 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 8620093 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 24946630 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24946630 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 24946630 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 24946630 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24946630 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 24946630 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 24946630 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 23066737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16116046 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9576125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8584772 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2236433 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30497684 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30497684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27986549 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 27986549 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27986549 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 20135132 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 11402910 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11402910 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22585884 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17645076 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 29169838 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23269286 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 23269286 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 11902023 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 21982649 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19238654 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 19238654 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 10882574 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 8807623 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31256445 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20061913 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16051709 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 11973410 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20926021 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 10597554 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 8605791 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 7649596 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 26058489 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23834132 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21745625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19880459 — Biomarker: HTR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2A; HTR2
Study 19880459 — Biomarker: GRIK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIK4; GRIK
Study 19880459 — Biomarker: KCNAB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNAB2; KCNA2B; KCNK2
Study 19880459 — Biomarker: FKBP5 mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: FKBP5; AIG6; FKBP51
Study 19880459 — Biomarker: PDE11A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE11A
Study 19880459 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 19880459 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 19880459 — Biomarker: GRIA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIA3; GLUR3; GLURC
Study 19880459 — Biomarker: PAPLN mRNA
Type: Predictive Biomarker (PRD)
Genes: PAPLN; UNQ2420/PRO4977
Study 1544289 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4054204 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29914666 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 29914666 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 29914666 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29914666 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 29914666 — Biomarker: TLR2
Type: Predictive Biomarker (PRD)
Genes: TIL4; CD282
Study 29914666 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9856962 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30265586 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study 28069040 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28069040 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8437596 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 18341673 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 10606361 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 31865336 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 31865336 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31865336 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31865336 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 31865336 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 21878067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)