AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 28179226 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22980098 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7988343 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 30227980 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25169589 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 19894365 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 17076319 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 14658015 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14658015 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27379922 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30196790 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27863211 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 22104026 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 22104026 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16687913 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 16687913 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 29552783 — Biomarker: ADAM17 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM17; CSVP; TACE
Study 20332274 — Biomarker: MLH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MLH1; COCA2
Study 20332274 — Biomarker: DNA mismatch repair protein MSH2
Type: Predictive Biomarker (PRD)
Genes: MSH2
Study 29685591 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 29685591 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 29685591 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29685591 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20031796 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20031796 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11300367 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8972016 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study 24311723 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 24311723 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 10907971 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28904371 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24158664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30138422 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 18728024 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 15811142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21367921 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 17173900 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31583436 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 28183276 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 23726373 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 20110084 — Biomarker: PDE1A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE1A
Study 20110084 — Biomarker: PDE1C mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE1C
Study 20110084 — Biomarker: PDE11A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE11A
Study 20110084 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 20110084 — Biomarker: GRIK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIK4; GRIK
Study 20110084 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 30012187 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 30012187 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 24361739 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 17442998 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 16082603 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 10633886 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 10633886 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 1663053 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 27023825 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 7623991 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25824327 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 25824327 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1550223 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 23803591 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10996232 — Biomarker: TYMP mRNA
Type: Predictive Biomarker (PRD)
Genes: TYMP; ECGF1
Study 10996232 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 28585182 — Biomarker: Urinary total protein
Type: Safety Biomarker (SAF)
Study 20131302 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 16365061 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 12860366 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 9058684 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 25917060 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25917060 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25917060 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 25917060 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 10523461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31977825 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 26026604 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25682570 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 25682570 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 16368299 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3929553 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31790604 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31790604 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27721227 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12925455 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 1449918 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21975350 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 25670917 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25119853 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25119853 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19262229 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 11576953 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11576953 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11576953 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11576953 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 21991729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15641874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9080920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30919549 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20816118 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18947338 — Biomarker: PGP mRNA
Type: Predictive Biomarker (PRD)
Genes: PGP
Study 15939064 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1955196 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 25424602 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 25424602 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25424602 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15005733 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 31855297 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26477278 — Biomarker: MOXD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MOXD1; MOX; UNQ2493/PRO5780
Study 23444134 — Biomarker: BMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BMP2; BMP2A
Study 21568746 — Biomarker: TCHH mRNA
Type: Predictive Biomarker (PRD)
Genes: TCHH; THH; THL; TRHY
Study 21985500 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15690201 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11755749 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 28596023 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28596023 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 25939604 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 25939604 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17014006 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 17014006 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 17014006 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 17014006 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17014006 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17014006 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 17014006 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11317165 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11317165 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30025470 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19066295 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11890163 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 21812263 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21812263 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21812263 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 19442784 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 15468351 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 23297772 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 20492045 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15922478 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 8677192 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 1854252 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28482106 — Biomarker: MMD mRNA
Type: Predictive Biomarker (PRD)
Genes: MMD; PAQR11
Study 26209003 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22421631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28704126 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 27228433 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24533697 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24533697 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30683061 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30683061 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28424871 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 18834464 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18834464 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 18834464 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 18834464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8793416 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12933402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11103227 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 1728202 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9951784 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20951147 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20951147 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20562702 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20562702 — Biomarker: Serum methemoglobin
Type: Surrogate Endpoint (SUR)
Study 11925355 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 3075410 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3075410 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 3075410 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31048415 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25416486 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 19858233 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 19858233 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19858233 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 19858233 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17885562 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24429201 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24815851 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11994377 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22428493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2953380 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15503832 — Biomarker: UBXN11 mRNA
Type: Predictive Biomarker (PRD)
Genes: UBXN11; SOC; UBXD5; PP2243
Study 11240116 — Biomarker: PCSK7 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK7; LPC; PC7; PC8; SPC7
Study 25116277 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22884766 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 20413736 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20413736 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1743759 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20216318 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28537012 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25514619 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11396234 — Biomarker: REG3A mRNA
Type: Predictive Biomarker (PRD)
Genes: REG3A; HIP; PAP; PAP1
Study 9506661 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 8794413 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7270561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21068008 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15468020 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 11441198 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1562096 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1562096 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24531833 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 17564290 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12322819 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7106840 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 11603100 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 9587722 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28993388 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12076867 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29217455 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 12584786 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12584786 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 12584786 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25039675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16033861 — Biomarker: SLC12A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC12A3; NCC; TSC
Study 31398065 — Biomarker: COTL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COTL1; CLP
Study 16968106 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16968106 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3090830 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 1378147 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31059641 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 28578601 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26781417 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 16291984 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11889322 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 28763898 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28763898 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21591581 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 17389264 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12018715 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16243716 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 2215254 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 31842259 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27473440 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 27473440 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 2142756 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 2142756 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 29169877 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24445723 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22370535 — Biomarker: PLK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLK1; PLK
Study 23181618 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20859679 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16784898 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11888949 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 26374825 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 26374825 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR