AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 27130369 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27130369 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 27130369 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27130369 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 27130369 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 24059271 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1730902 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18495737 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15888509 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12560439 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10836329 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7024767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24382482 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 28489468 — Biomarker: TAAR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAAR1; TA1; TAR1; TRAR1
Study 28489468 — Biomarker: TAAR9 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAAR9; TA3; TAR3; TRAR3
Study 23953101 — Biomarker: PBK mRNA
Type: Predictive Biomarker (PRD)
Genes: PBK; TOPK
Study 21787184 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 21787184 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26473751 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19838638 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 17936861 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 7026794 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28403531 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25733639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24393375 — Biomarker: FAIM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FAIM2; KIAA0950; LFG; LFG2; NMP35; TMBIM2
Study 16283605 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 7467379 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15155712 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 11268267 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11268267 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 11268267 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 26483357 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7149870 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30566166 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 25349296 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 7527326 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7527326 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12900738 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 30170424 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 28850535 — Biomarker: MPG mRNA
Type: Predictive Biomarker (PRD)
Genes: MPG; AAG; ANPG; MID1
Study 15694942 — Biomarker: APOA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOA1
Study 15694942 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15694942 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6756273 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27048949 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 20140523 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12600722 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 8858268 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27058799 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27058799 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17959539 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17959539 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15871189 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10720857 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9368810 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9368810 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18484415 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16368837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14576510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19671948 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 8427664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18525491 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28941144 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15975149 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 23121473 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20453627 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18822982 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 10526698 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7839425 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2495049 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7043304 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18836704 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 17505072 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 14871425 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 8021761 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 28109266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26516910 — Biomarker: MGP mRNA
Type: Predictive Biomarker (PRD)
Genes: MGP; MGLAP; GIG36
Study 22030782 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22030782 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 1736759 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 6474360 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 29732731 — Biomarker: LPAR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LPAR1; EDG2; LPA1
Study 12840089 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30764582 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30764582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30213037 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25089931 — Biomarker: IL1RN mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RN; IL1F3; IL1RA
Study 20830731 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 20830731 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15850080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27681702 — Biomarker: CTRC mRNA
Type: Predictive Biomarker (PRD)
Genes: CTRC; CLCR
Study 21465735 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8936563 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 23482473 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23482473 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22322357 — Biomarker: HSPA1B mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA1B; HSP72
Study 11850711 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 25697576 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25697576 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25697576 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25697576 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25697576 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20085937 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20085937 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18574759 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 15983245 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15983245 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11957789 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 30842160 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30842160 — Biomarker: C-C motif chemokine 4
Type: Monitoring Biomarker (MOI)
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 30842160 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30842160 — Biomarker: T-cell specific protein RANTES
Type: Safety Biomarker (SAF)
Genes: CCL5; D17S136E; SCYA5
Study 7804511 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7804511 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 26041459 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22963833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24432626 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21668635 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 21897336 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 16492692 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 16492692 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22704412 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22704412 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22704412 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9890391 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 8808232 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30284597 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 26296296 — Biomarker: FST mRNA
Type: Predictive Biomarker (PRD)
Genes: FST
Study 7942055 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7942055 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23108496 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22133036 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8236142 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 8236142 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 27843051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27074034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17583098 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22370319 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 15033251 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11695068 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27576370 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 30640138 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30640138 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28431432 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 25510442 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 15492182 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 3802717 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 3802717 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12955553 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9343031 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 17716544 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17716544 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9490235 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28318759 — Biomarker: ASAH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASAH1; ASAH; HSD-33; HSD33
Study 18074149 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22097197 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 7900949 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1999714 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 31476451 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 28634644 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 15963096 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 10321421 — Biomarker: NPL mRNA
Type: Predictive Biomarker (PRD)
Genes: NPL; C1orf13
Study 8921782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27696727 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27696727 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23788270 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15352908 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12161007 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 21951464 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21951464 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21951464 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16769945 — Biomarker: Lysosomal alpha-glucosidase
Type: Safety Biomarker (SAF)
Genes: GAA
Study 15050490 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 8387085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25042931 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 12812864 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 10754621 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1639464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6539613 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 12081158 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12081158 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11544459 — Biomarker: PTPRF mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRF; LAR
Study 11544459 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27783213 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 27783213 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 27783213 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23218801 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18316163 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 9339943 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 9339943 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8416449 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10326702 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 29797109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14632722 — Biomarker: NPL mRNA
Type: Predictive Biomarker (PRD)
Genes: NPL; C1orf13
Study 14632722 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1857992 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 29978257 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24335695 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 20862944 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20862944 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 20862944 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 18678300 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12915664 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 16329539 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24465030 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 24465030 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12045644 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19377384 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 25097102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19890745 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12770969 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 8862223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31265163 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27628617 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 22796581 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22796581 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 22796581 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 15590232 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12149467 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12149467 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28430117 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25545400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11799385 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10182195 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7975870 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12225613 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 30227457 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24755148 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 22445438 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 28296349 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 22741260 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 15670541 — Biomarker: CLC mRNA
Type: Predictive Biomarker (PRD)
Genes: CLC; LGALS10; LGALS10A
Study 24714360 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 3858912 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21519151 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17201213 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10878703 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)