AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 10369491 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 786694 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31234234 — Biomarker: HMMR mRNA
Type: Predictive Biomarker (PRD)
Genes: HMMR; IHABP; RHAMM
Study 23937692 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 22781571 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 25483598 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 25483598 — Biomarker: Th2 cell
Type: Safety Biomarker (SAF)
Study 20068404 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 9694611 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25984891 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9794735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9794735 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31512365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22739747 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 19001830 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 17024647 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7708266 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7708266 — Biomarker: TNFR1B
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 30613020 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 30613020 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30613020 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18505112 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 31100534 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 31100534 — Biomarker: GIPR mRNA
Type: Predictive Biomarker (PRD)
Genes: GIPR
Study 17906182 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 16135576 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10457271 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31298823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11137745 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 11137745 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7930741 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 28303421 — Biomarker: OXTR mRNA
Type: Predictive Biomarker (PRD)
Genes: OXTR
Study 28167746 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 21692235 — Biomarker: LNX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LNX1; LNX; PDZRN2; UNQ574/PRO1136
Study 9223109 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 21963834 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21963834 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21937568 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 31297962 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30165522 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12799102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10372237 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1839161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24667908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22871128 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 2291867 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31199705 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31199705 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31199705 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 28575224 — Biomarker: DHCR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: DHCR7; D7SR
Study 28575224 — Biomarker: CYP2R1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2R1
Study 28575224 — Biomarker: CYP24A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP24A1; CYP24
Study 28575224 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 28029540 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 24929023 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 24929023 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24929023 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22344504 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22344504 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9356038 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 7706591 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31085097 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 26927446 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19602719 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 14734438 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24129613 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 24129613 — Biomarker: CD6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD6
Study 25199825 — Biomarker: DDN mRNA
Type: Predictive Biomarker (PRD)
Genes: DDN; KIAA0749
Study 2719760 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2719760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2719760 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 11054200 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23291141 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 15634033 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26426148 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23735514 — Biomarker: MAP2K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K1; MEK1; PRKMK1
Study 12728489 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 22219221 — Biomarker: DRD3
Type: Safety Biomarker (SAF)
Study 12474069 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 12474069 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12474069 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2674028 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20473910 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 20473910 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 26041481 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 26041481 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 23146365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15630501 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 7586935 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28642340 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21659891 — Biomarker: CDS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDS1; CDS
Study 17933414 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 12774016 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 9357377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9357377 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 1588824 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 2862995 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24661672 — Biomarker: SPARCL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPARCL1
Study 14512132 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 17312210 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28960777 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 28960777 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 28960777 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16525138 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31382965 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 11575224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8269798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8269798 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31522180 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 18343739 — Biomarker: ACRC mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNA; ACRC
Study 12726869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25144793 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17076857 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 17076857 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12679389 — Biomarker: TPM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPM1; C15orf13; TMSA
Study 25558638 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22479542 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22479542 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 785959 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 785959 — Biomarker: Urinary total protein
Type: Safety Biomarker (SAF)
Study 22698005 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 22698005 — Biomarker: Epithelial cadherin
Type: Predictive Biomarker (PRD)
Genes: CDH1; CDHE; UVO
Study 17327342 — Biomarker: NANOS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS3; NOS3
Study 15467218 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 10391259 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31440799 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 28892656 — Biomarker: miR-15a
Type: Safety Biomarker (SAF)
Genes: MIR15A
Study 25789421 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 31390883 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 31390883 — Biomarker: LRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LRP1; A2MR; APR
Study 29725828 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 5015036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12755932 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10629456 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 24424781 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 17087785 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 12800105 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29458404 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 21831167 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27342222 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 11233387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11233387 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 7838619 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28267471 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 25946654 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 25946654 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 25946654 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19505293 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16622120 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 29768290 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22713720 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 28025538 — Biomarker: SSB mRNA
Type: Predictive Biomarker (PRD)
Genes: SSB
Study 20202859 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20202859 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 20202859 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 16492404 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 7625467 — Biomarker: PTK7 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTK7; CCK4
Study 30218286 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28515164 — Biomarker: SLC39A8 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC39A8; BIGM103; ZIP8; PP3105
Study 28515164 — Biomarker: SLC39A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC39A1; IRT1; ZIP1; ZIRTL; CGI-08; CGI-71
Study 25312998 — Biomarker: MPST mRNA
Type: Predictive Biomarker (PRD)
Genes: MPST; TST2
Study 23748441 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 16705487 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16705487 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 9232361 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21614411 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 12831624 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 12831624 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 12831624 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 12831624 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 28466679 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28466679 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 27428671 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27428671 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 27428671 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 27428671 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 21293163 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 19267407 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9269788 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9269788 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19263034 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9205013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26786000 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 16444450 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16444450 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11774859 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8344693 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29752304 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 22005962 — Biomarker: SLMAP mRNA
Type: Predictive Biomarker (PRD)
Genes: SLMAP; KIAA1601; SLAP; UNQ1847/PRO3577
Study 18284400 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18284400 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 29055489 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22851600 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17575559 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 12669741 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28079501 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28079501 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28079501 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28079501 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 22989372 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 19889690 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19889690 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18505181 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 29129443 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26852501 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16785738 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19004201 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 31294749 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 25822236 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23434449 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23434449 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 26412178 — Biomarker: AHSP mRNA
Type: Predictive Biomarker (PRD)
Genes: AHSP; EDRF; ERAF
Study 19117033 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21150602 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16389160 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27982269 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26302034 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 30882595 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22465578 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18039351 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16200601 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14612278 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14612278 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7008475 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 8088970 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3406600 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24996197 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17645384 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31915170 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 30849947 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23143672 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7683480 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 2961688 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 2961688 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29119530 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 9440719 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 9440719 — Biomarker: NRSN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRSN1; VMP