AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT00810693 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study NCT02629523 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02629523 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT02629523 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study NCT01626495 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT04148820 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT02853071 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT02853071 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02853071 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT02853071 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT04901000 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study NCT02660931 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT02712671 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT02712671 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT01127217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03912064 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study NCT02321046 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01800799 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study NCT00226798 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT01617525 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02479516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01469234 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT03836339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02674776 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02674776 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT03090984 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study NCT03090984 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study NCT00722553 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT00319631 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00319631 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT00482638 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00440596 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01008813 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT03896997 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study NCT01055353 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04033510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03078907 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT01013948 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT03166878 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT03166878 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study NCT02571205 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study NCT02571205 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00736294 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT04633772 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885
Study NCT04633772 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT01795638 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study NCT00443157 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study NCT02362737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04030234 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00019357 — Biomarker: RAS peptides
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00019357 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT02714010 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05201742 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT03520712 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT04138069 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04138069 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT02527837 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study NCT02527837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01548872 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study NCT01499069 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study NCT00315536 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04516369 — Biomarker: RPE65 mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE65
Study NCT00684164 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study NCT01722396 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study NCT01933711 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT02515643 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03206827 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01242228 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT01086605 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00363012 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04500639 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885
Study NCT04500639 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT01853748 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02329782 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00001137 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT03157960 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study NCT03157960 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT00303160 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT00743197 — Biomarker: TGFB1
Type: Safety Biomarker (SAF)
Genes: CED; TGFbeta
Study NCT02727413 — Biomarker: CPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPB1; CPB; PCPB
Study NCT02727413 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT02727413 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04104334 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00027937 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00027937 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study NCT00027937 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT00806715 — Biomarker: HFE mRNA
Type: Predictive Biomarker (PRD)
Genes: HFE; HLAH
Study NCT04731831 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04731831 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study NCT02277457 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02277457 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT02277457 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03452150 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03452150 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03781544 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01106534 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study NCT02929992 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT03180593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03361358 — Biomarker: MTAP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTAP; MSAP
Study NCT05260372 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study NCT00450372 — Biomarker: Argininosuccinate synthase
Type: Safety Biomarker (SAF)
Genes: ASS1; ASS
Study NCT00999622 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00999622 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT05520385 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study NCT01249859 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study NCT00458861 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT02214186 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study NCT02214186 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study NCT04424550 — Biomarker: PBK mRNA
Type: Predictive Biomarker (PRD)
Genes: PBK; TOPK
Study NCT01062763 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01669928 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00690222 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02169284 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00250523 — Biomarker: IRAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRAK1; IRAK
Study NCT01008150 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02148107 — Biomarker: LTA4H mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA4H; LTA4
Study NCT03467477 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT02392611 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT03470948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03845543 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study NCT04281043 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study NCT00545935 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study NCT00317954 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00004464 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT02455882 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT02511509 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT02511509 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study NCT02511509 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT03422263 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT01437956 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study NCT01642407 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT01558193 — Biomarker: DBH mRNA
Type: Predictive Biomarker (PRD)
Genes: DBH
Study NCT01558193 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study NCT01558193 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study NCT01558193 — Biomarker: DRD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD1
Study NCT01558193 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study NCT01558193 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study NCT01558193 — Biomarker: TPH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH2; NTPH
Study NCT01558193 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study NCT01558193 — Biomarker: HTR1A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR1A; ADRB2RL1; ADRBRL1
Study NCT01558193 — Biomarker: HTR1B mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR1B; HTR1DB
Study NCT01558193 — Biomarker: HTR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2A; HTR2
Study NCT01558193 — Biomarker: HTR2B mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2B
Study NCT01558193 — Biomarker: HTR2C mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2C; HTR1C
Study NCT01558193 — Biomarker: HTR3A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR3A; 5HT3R; HTR3
Study NCT01558193 — Biomarker: HTR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR4
Study NCT01558193 — Biomarker: ADRA2A mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRA2A; ADRA2R; ADRAR
Study NCT01558193 — Biomarker: ADRB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB1; ADRB1R; B1AR
Study NCT01558193 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study NCT01558193 — Biomarker: ADRB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB3; ADRB3R; B3AR
Study NCT01558193 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study NCT01558193 — Biomarker: DRD3
Type: Safety Biomarker (SAF)
Study NCT01771380 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study NCT01713699 — Biomarker: EPCAM mRNA
Type: Predictive Biomarker (PRD)
Genes: EPCAM; GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1
Study NCT02448810 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT02448810 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study NCT02883842 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01268150 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01268150 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT01140685 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study NCT01527318 — Biomarker: PNPLA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PNPLA2; ATGL; FP17548
Study NCT01527318 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study NCT01147172 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT05490771 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study NCT05490771 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study NCT00208949 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT03381248 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT00674427 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study NCT03313219 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study NCT02606955 — Biomarker: REST mRNA
Type: Predictive Biomarker (PRD)
Genes: REST; NRSF; XBR
Study NCT02533648 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT01565174 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study NCT01142505 — Biomarker: ALOX5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALOX5; LOG5
Study NCT00003099 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study NCT01522833 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01522833 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT02163655 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03737799 — Biomarker: SCPEP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SCPEP1; RISC; SCP1; MSTP034; UNQ265/PRO302
Study NCT01729598 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03014219 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT03262974 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study NCT03262974 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study NCT03262974 — Biomarker: SLC22A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A1; OCT1
Study NCT00003190 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT04143087 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT04143087 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT01097915 — Biomarker: CA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA6
Study NCT02920164 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03561350 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study NCT03561350 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study NCT00200161 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study NCT03117972 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT00612222 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT02534584 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT03318900 — Biomarker: TNFRSF9 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF9; CD137; ILA
Study NCT00776724 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study NCT02840773 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study NCT05345366 — Biomarker: CITED2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CITED2; MRG1
Study NCT05345366 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT05345366 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study NCT05345366 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT02797145 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT01678443 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study NCT00005788 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT01478113 — Biomarker: AMPH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMPH; AMPH1
Study NCT04098796 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study NCT03781089 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study NCT03672643 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT03672643 — Biomarker: ROS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROS1; MCF3; ROS
Study NCT04430192 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00240968 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT02561546 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study NCT00420719 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study NCT00576524 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04238052 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00383604 — Biomarker: FOXC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXC2; FKHL14; MFH1
Study NCT04156243 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT00118625 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study NCT00742820 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study NCT00634400 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT00437892 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT03300050 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT05253560 — Biomarker: Lysosomal acid glucosylceramidase
Type: Pharmacodynamic Biomarker (PDY)
Genes: GBA1; GBA; GC; GLUC
Study NCT00796185 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study NCT00796185 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT00796185 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study NCT04439175 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study NCT04289701 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03056664 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT03601156 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study NCT02597868 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02597868 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT02597868 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT02556827 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study NCT02556827 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study NCT04467931 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885
Study NCT04467931 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT02199821 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00774358 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT00409786 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)