AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 22353811 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 17420344 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16390748 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 16390748 — Biomarker: SMPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMPD1; ASM
Study 28536029 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28536029 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25492271 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 22885164 — Biomarker: FCGR3A mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 22885164 — Biomarker: FCGR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR2A; CD32; FCG2; FCGR2A1; IGFR2
Study 18335394 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2288835 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30608620 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 30608620 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15119693 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11766367 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11766367 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 9489910 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9489910 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 27903675 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27903675 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27903675 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 21177797 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20039931 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20039931 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 20039931 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20395096 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 18555812 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 18555812 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18555812 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 16003231 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12484508 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12484508 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12484508 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 29548945 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29548945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29548945 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29548945 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9649261 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 28554908 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 10680096 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8409786 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 31736357 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 7841660 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 30029486 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25703666 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25703666 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 10822283 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10822283 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10822283 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22943199 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22943199 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 22943199 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20691042 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 6188917 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26759975 — Biomarker: RRAD mRNA
Type: Predictive Biomarker (PRD)
Genes: RRAD; RAD
Study 9740606 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29246725 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 26707868 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22715739 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 19671263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17576400 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10813372 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8829885 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6332895 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 23958115 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17884342 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17884342 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17884342 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14562994 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6367863 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 29039254 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 17915406 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15043514 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27321772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7759785 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 21910341 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 19822977 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16986348 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 16986348 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 11019424 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29685013 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16393327 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16393327 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16393327 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 14652007 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 8841157 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21040693 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 2349956 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2349956 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31544469 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1163095 — Biomarker: HBE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HBE1; HBE
Study 18676982 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26428281 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22550054 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22550054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30977312 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 23735181 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 15502727 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30841655 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12062320 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 7878170 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 31029921 — Biomarker: ADIPOQ mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 31029921 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10741623 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 27355231 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29777264 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20859551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17409842 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 12854835 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12854835 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10795771 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 8642191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24866574 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 18557665 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 18557665 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 2149674 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2149674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7025264 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22027686 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 17530112 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 11148914 — Biomarker: UBXN11 mRNA
Type: Predictive Biomarker (PRD)
Genes: UBXN11; SOC; UBXD5; PP2243
Study 10636373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28544580 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 25338187 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 2176795 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2176795 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 30853262 — Biomarker: ID1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ID1; BHLHB24; ID
Study 30710858 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 10368452 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 10368452 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 26296069 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 24437213 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27343021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16651463 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1539469 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11192307 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 25363733 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 25363733 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 16312178 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2361594 — Biomarker: KCNH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNH2; ERG; ERG1; HERG
Study 29809075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16856976 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 16856976 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 8877664 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 6137293 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15467292 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 28668276 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28668276 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19089438 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19089438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2906953 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29893790 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29893790 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20019672 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18614956 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 26657066 — Biomarker: miR-22
Type: Safety Biomarker (SAF)
Genes: MIR22
Study 26657066 — Biomarker: let-7b
Type: Predictive Biomarker (PRD)
Genes: MIRLET7B
Study 26657066 — Biomarker: miR-200a
Type: Safety Biomarker (SAF)
Genes: MIR200A
Study 12149660 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 12149660 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30287210 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22284340 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22284340 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19080711 — Biomarker: CTLA4
Type: Predictive Biomarker (PRD)
Genes: CD152; CD; GSE; CTLA-4
Study 16882108 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16882108 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31537219 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30161205 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26794168 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 25811824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25811824 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25811824 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22339238 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19298023 — Biomarker: PPOX
Type: Safety Biomarker (SAF)
Genes: HCRT; OX
Study 15778240 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9028511 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1900480 — Biomarker: TMEM37 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMEM37; PR
Study 31634646 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24356952 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 24356952 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18025884 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18025884 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10426837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11839994 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31222379 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15604915 — Biomarker: ADM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADM2; AM2
Study 11289051 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11289051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9647874 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7847107 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 7847107 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 1971778 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 31358390 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 31358390 — Biomarker: GLS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS2; GA
Study 2903105 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 2903105 — Biomarker: Connecting peptide
Type: Safety Biomarker (SAF)
Genes: AHSG; FETUA; PRO2743
Study 24622413 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17927495 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 27484126 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 10658943 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10658943 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8574257 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8574257 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 518286 — Biomarker: Plasma testosterone level
Type: Surrogate Endpoint (SUR)
Study 3110562 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29940888 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29940888 — Biomarker: IL15 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL15
Study 25245386 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22673596 — Biomarker: GYPC mRNA
Type: Predictive Biomarker (PRD)
Genes: GYPC; GLPC; GPC
Study 18822979 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 18822979 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 18822979 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23747768 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20354688 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 18191056 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3905326 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 26748844 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10720024 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 28202441 — Biomarker: LSR mRNA
Type: Predictive Biomarker (PRD)
Genes: LSR; ILDR3; LISCH
Study 23648698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6361300 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6361300 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24904022 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 22442825 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 19736246 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 19736246 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19736246 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 18932258 — Biomarker: THBS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: THBS1; TSP; TSP1
Study 14507272 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31999530 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26872548 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26872548 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21030711 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7609571 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 29083331 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 29083331 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21593114 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2875812 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2875812 — Biomarker: Succinate-semialdehyde dehydrogenase
Type: Safety Biomarker (SAF)
Genes: ALDH5A1; SSADH
Study 29635061 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 24585406 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23109900 — Biomarker: ACAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAT1; ACAT; MAT
Study 23109900 — Biomarker: LIPC mRNA
Type: Predictive Biomarker (PRD)
Genes: LIPC; HTGL
Study 23109900 — Biomarker: LIPG mRNA
Type: Predictive Biomarker (PRD)
Genes: LIPG; UNQ387/PRO719
Study 23109900 — Biomarker: MYLIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MYLIP; BZF1; IDOL; BM-023; PP5242
Study 23109900 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052