AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 21668924 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 21669404 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 21670448 — Biomarker: DNMT3A mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMT3A
Study 21670448 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 21670448 — Biomarker: CEBPA mRNA
Type: Predictive Biomarker (PRD)
Genes: CEBPA; CEBP
Study 21670448 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 21670448 — Biomarker: IDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH2
Study 21670448 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 21670448 — Biomarker: WT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WT1
Study 21670448 — Biomarker: BAALC mRNA
Type: Predictive Biomarker (PRD)
Genes: BAALC
Study 21670448 — Biomarker: MECOM mRNA
Type: Predictive Biomarker (PRD)
Genes: MECOM; EVI1; MDS1; PRDM3
Study 21670448 — Biomarker: KMT2E mRNA
Type: Predictive Biomarker (PRD)
Genes: KMT2E; MLL5
Study 21670449 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 21673350 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study 21674002 — Biomarker: GCKR mRNA
Type: Predictive Biomarker (PRD)
Genes: GCKR
Study 21674002 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21676042 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 21676217 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 21676217 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21676217 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 21676217 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 21676222 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 21676394 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21677057 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 21677057 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21679735 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21680644 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 21680850 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21680946 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21685174 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 21685174 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 21685540 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21689421 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 21694639 — Biomarker: PKHD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PKHD1; FCYT; TIGM1
Study 21696575 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 21699369 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21699369 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21699369 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21700776 — Biomarker: DNMT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMT1; AIM; CXXC9; DNMT
Study 21701566 — Biomarker: ACACB mRNA
Type: Predictive Biomarker (PRD)
Genes: ACACB; ACC2; ACCB
Study 21701566 — Biomarker: DGAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DGAT1; AGRP1; DGAT
Study 21701566 — Biomarker: NKRF mRNA
Type: Predictive Biomarker (PRD)
Genes: NKRF; ITBA4; NRF
Study 21701566 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 21701807 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21701807 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21704134 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21704134 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 21704134 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21704134 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 21704784 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 21704887 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 21704964 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21706288 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21706316 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 21706316 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 21712287 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21714604 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21716163 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 21716260 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21716303 — Biomarker: Fibroblast growth factor 1
Type: Safety Biomarker (SAF)
Genes: FGF1
Study 21719129 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21719124 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 21719418 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 21719884 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 21725047 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 21725050 — Biomarker: Macrophage inflammatory protein 1-alpha
Type: Monitoring Biomarker (MOI)
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 21725050 — Biomarker: C-C motif chemokine 4
Type: Monitoring Biomarker (MOI)
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 21729182 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 21729732 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21730256 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 21730256 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21730256 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 21730256 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21730256 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 21730256 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 21730256 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 21733227 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 21733227 — Biomarker: SLC6A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 21733227 — Biomarker: ADRA2A mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRA2A; ADRA2R; ADRAR
Study 21733227 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 21733477 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 21735145 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21735145 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21737309 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21738597 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21738597 — Biomarker: Undetectable plasma HIV RNA
Type: Surrogate Endpoint (SUR)
Study 21740673 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21741058 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 21749698 — Biomarker: XRCC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: XRCC3
Study 21749698 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 21749698 — Biomarker: GSTA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTA1
Study 21749698 — Biomarker: RAD51 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAD51; RAD51A; RECA
Study 21752435 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 21752435 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 21752947 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 21755013 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 21756035 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 21756035 — Biomarker: CLEC4D mRNA
Type: Predictive Biomarker (PRD)
Genes: CLEC4D; CLECSF8; MCL
Study 21756320 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21757572 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 21757586 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 21757630 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21757643 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 21757643 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 21760886 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 21761342 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 21762873 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21763168 — Biomarker: CPT1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CPT1A; CPT1
Study 21763168 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21763653 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 21764499 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 21764499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21765124 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 21767228 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 21767331 — Biomarker: EML4 mRNA
Type: Predictive Biomarker (PRD)
Genes: EML4; C2orf2; EMAPL4
Study 21767331 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 21769849 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21772051 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21775114 — Biomarker: OLR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OLR1; CLEC8A; LOX1
Study 21775114 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21777076 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21777890 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 21778257 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 21778257 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 21782507 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 21782507 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 21782507 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 21784508 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 21787417 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 21787417 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21787417 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21791058 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21791415 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 21791415 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21791469 — Biomarker: CYP17A1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CYP17A1; CYP17; S17AH
Study 21791513 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 21791540 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 21791540 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21791540 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21791546 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21791546 — Biomarker: EDNRA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDNRA; ETA; ETRA
Study 21791546 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 21791546 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21791591 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 21791687 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 21794906 — Biomarker: CCR3 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CCR3; CMKBR3
Study 21794906 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 21799175 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 21799175 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 21802835 — Biomarker: TMPRSS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMPRSS2; PRSS10
Study 21802881 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21803569 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21804667 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 21805607 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21809989 — Biomarker: OTX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OTX2
Study 21812019 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21812019 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21812736 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 21814460 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 21816436 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 21816790 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21816832 — Biomarker: GATA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GATA2
Study 21816833 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 21816912 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study 21819438 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21819507 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21819507 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 21819507 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21820136 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21821014 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21821340 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21823120 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21823912 — Biomarker: CGAS mRNA
Type: Predictive Biomarker (PRD)
Genes: CGAS; C6orf150; MB21D1
Study 21824458 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 21826527 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21827541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21828124 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 21828134 — Biomarker: ASXL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASXL1; KIAA0978
Study 21828134 — Biomarker: TET2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET2; KIAA1546; Nbla00191
Study 21828134 — Biomarker: RUNX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX1; AML1; CBFA2
Study 21828134 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 21828134 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 21828134 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 21828134 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 21828134 — Biomarker: JAK2
Type: Predictive Biomarker (PRD)
Genes: JTK10
Study 21828141 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 21828142 — Biomarker: PDGFRA mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 21828142 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 21828157 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21831685 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 21832276 — Biomarker: Platelet count response
Type: Surrogate Endpoint (SUR)
Study 21833452 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21833452 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study 21835005 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21836143 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 21836147 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 21838881 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 21844482 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21846339 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21846636 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21849486 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 21851846 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21851846 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21852114 — Biomarker: Aurora kinase A
Type: Predictive Biomarker (PRD)
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 21856867 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 21857286 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21857490 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 21857490 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21859692 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21860347 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21860347 — Biomarker: CTBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CTBS; CTB
Study 21862407 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 21862407 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 21865328 — Biomarker: AFM mRNA
Type: Predictive Biomarker (PRD)
Genes: AFM; ALB2; ALBA
Study 21865328 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 21865328 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21865346 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 21865361 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 21865561 — Biomarker: TCN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCN2; TC2
Study 21867843 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21868014 — Biomarker: ATP2B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATP2B1; PMCA1
Study 21868014 — Biomarker: DMPK mRNA
Type: Predictive Biomarker (PRD)
Genes: DMPK; DM1PK; MDPK
Study 21868463 — Biomarker: TBP mRNA
Type: Predictive Biomarker (PRD)
Genes: TBP; GTF2D1; TF2D; TFIID
Study 21868463 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 21868572 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 21868778 — Biomarker: LGSN mRNA
Type: Predictive Biomarker (PRD)
Genes: LGSN; GLULD1; LGS
Study 21871057 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 21871057 — Biomarker: NR1H4 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study 21871057 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21871057 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21873548 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 21873548 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 21876119 — Biomarker: BCL11A mRNA
Type: Predictive Biomarker (PRD)
Genes: BCL11A; CTIP1; EVI9; KIAA1809; ZNF856
Study 21876119 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21877169 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 21877895 — Biomarker: GALNS mRNA
Type: Predictive Biomarker (PRD)
Genes: GALNS