AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 7490317 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7490317 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 7247733 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 16549997 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 14739683 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study 8839837 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8839837 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8839837 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27101291 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10722500 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 1444526 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19655157 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 17585086 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 27677368 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27677368 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19479626 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 15319599 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7803993 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 3052916 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 11319684 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11319684 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 9141913 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9141913 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2446080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29861437 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27466602 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 9089422 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9089422 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study 8478959 — Biomarker: SLC25A21 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A21; ODC
Study 16183781 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 16183781 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 16183781 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 16183781 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 8704114 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 31711417 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31711417 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18721085 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 27978537 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 16644631 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 10657761 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 22426952 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20722561 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30573499 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30695661 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 21737951 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 9203727 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 20413383 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24219891 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24219891 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 24219891 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 16143696 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2208231 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22843282 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 22843282 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 9700992 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18458358 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10789569 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10789569 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 10789569 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 30353303 — Biomarker: ARSB mRNA
Type: Predictive Biomarker (PRD)
Genes: ARSB
Study 26540079 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 25178112 — Biomarker: CCRL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCRL2; CCR11; CCR6; CKRX; CRAM; HCR
Study 25178112 — Biomarker: CXCR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR3; GPR9
Study 25178112 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 20629810 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21383004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17157123 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17157123 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17157123 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14748202 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9528197 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 3219156 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26879683 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 23038989 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21436597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19159566 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 7908356 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29404725 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28490337 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 28490337 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28490337 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9051165 — Biomarker: PAG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAG1; CBP; PAG
Study 24557989 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 24557989 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 28556432 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 18048433 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18048433 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 18048433 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 27922020 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23807278 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23248063 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7677296 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6972513 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 25870986 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25870986 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25525195 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23081681 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 21729811 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21729811 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26576673 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18433043 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18433043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18433043 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 12663273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10217581 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27166171 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 29370144 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29370144 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 15570920 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 15570920 — Biomarker: Dihydrothymine dehydrogenase
Type: Safety Biomarker (SAF)
Genes: DPYD
Study 9310275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25876351 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20636965 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7502516 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7502516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19244040 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study 19244040 — Biomarker: NF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF2; SCH
Study 17578786 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9260367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2832287 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 2832287 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 21372003 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 15353455 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23283428 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 16962345 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22821424 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10741701 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 30309839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31721185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29246361 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 24636474 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 20093149 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 10408635 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31570105 — Biomarker: HNF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: HNF1A; TCF1
Study 31570105 — Biomarker: BAX mRNA
Type: Predictive Biomarker (PRD)
Genes: BAX; BCL2L4
Study 31570105 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 31570105 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 17635939 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2140735 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 23990195 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22773769 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15093987 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9257889 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9257889 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 31420414 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 17043961 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17043961 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 6378437 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20199178 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20199178 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20199178 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10029055 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 30950565 — Biomarker: DGAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DGAT1; AGRP1; DGAT
Study 30950565 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9815633 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 26214555 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17912501 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 15868614 — Biomarker: MAF mRNA
Type: Predictive Biomarker (PRD)
Genes: MAF
Study 15868614 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 28017706 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 8033544 — Biomarker: SIGLEC12 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIGLEC12; SIGLECL1; SLG; UNQ9215/PRO34042
Study 27986412 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 14666025 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 14666025 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 14666025 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 26118315 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 26118315 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 24934242 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 11555126 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 8185469 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 3237594 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 17179023 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11230831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3402355 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31418585 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31418585 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31418585 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28493932 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23545150 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 9741655 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study 8059044 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28632865 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 26156277 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2184133 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21703848 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 16249540 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 8240197 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30514741 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16567272 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10892822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14731163 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9392500 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 3048870 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 31790692 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 30454001 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12957426 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 31575375 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31575375 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25253123 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30400372 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26524933 — Biomarker: SLMAP mRNA
Type: Predictive Biomarker (PRD)
Genes: SLMAP; KIAA1601; SLAP; UNQ1847/PRO3577
Study 26524933 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22295814 — Biomarker: LSS mRNA
Type: Predictive Biomarker (PRD)
Genes: LSS; OSC
Study 16022023 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 12446187 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 30325703 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26324362 — Biomarker: Dihydrothymine dehydrogenase
Type: Safety Biomarker (SAF)
Genes: DPYD
Study 20466200 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20466200 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18419497 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12545081 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29352007 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 27501833 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15077100 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 31138085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24191893 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10679534 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 29727369 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29727369 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 7738941 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17368065 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 2563788 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 29797689 — Biomarker: STIM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STIM1; GOK
Study 29797689 — Biomarker: STIM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: STIM2; KIAA1482
Study 20624256 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 30487209 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25349205 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15385360 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30935461 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 31644357 — Biomarker: REG3A mRNA
Type: Predictive Biomarker (PRD)
Genes: REG3A; HIP; PAP; PAP1
Study 31644357 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23672597 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23672597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11490238 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9550628 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9550628 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29474302 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27861249 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9222805 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16542292 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16542292 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15978302 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8598547 — Biomarker: SLC1A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC1A5; ASCT2; M7V1; RDR; RDRC
Study 31801245 — Biomarker: BAX mRNA
Type: Predictive Biomarker (PRD)
Genes: BAX; BCL2L4
Study 9077497 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22465317 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)