AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 20507375 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 1736694 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31085043 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31085043 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29698651 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29698651 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 12134102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30705097 — Biomarker: Serum asparaginase
Type: Surrogate Endpoint (SUR)
Study 15957997 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 2149053 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20535518 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20535518 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 14990637 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27187047 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19583677 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 29691148 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21952034 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21211387 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22982353 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19383221 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17461960 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 31422486 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 31422486 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15240411 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9678107 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 8471132 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 29503145 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19087716 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17112304 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17112304 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8862940 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8862940 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 1736500 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 25212457 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 16142596 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26573431 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 26573431 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 3300457 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31597523 — Biomarker: HIPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: HIPK3; DYRK6; FIST3; PKY
Study 31597523 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 31597523 — Biomarker: FOXM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXM1; FKHL16; HFH11; MPP2; WIN
Study 19182178 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 17483968 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 8043974 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8043974 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3052785 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 25522265 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 15015440 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 7870965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24887018 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 21211458 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21211458 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 29496255 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 29496255 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 22997204 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 30135888 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 22220807 — Biomarker: AFM mRNA
Type: Predictive Biomarker (PRD)
Genes: AFM; ALB2; ALBA
Study 22295891 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20554982 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8885957 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 8885957 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28929919 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30037301 — Biomarker: RRAD mRNA
Type: Predictive Biomarker (PRD)
Genes: RRAD; RAD
Study 30388751 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 19996066 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29231349 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12966367 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12966367 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10852440 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2895577 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19448566 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11884296 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 31587091 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 31623857 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 21836102 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21836102 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10090926 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 2084727 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26519 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12084021 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 20357176 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 16136044 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16136044 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16136044 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1951878 — Biomarker: SLC25A21 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A21; ODC
Study 20141248 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 15849806 — Biomarker: CYP1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A1
Study 15849806 — Biomarker: CYP2E1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2E1; CYP2E
Study 15849806 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 15849806 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 12227681 — Biomarker: TGFB1
Type: Safety Biomarker (SAF)
Genes: CED; TGFbeta
Study 12227681 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 12227681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3881561 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22898251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22898251 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22898251 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3315592 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 22503139 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22503139 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 22503139 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 22503139 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 9419782 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9419782 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 23132848 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19118825 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 19118825 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 16728231 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15226097 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 30840633 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30840633 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 30840633 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 30840633 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26000301 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 18842671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21788625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9194208 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27369111 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 11961610 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7646913 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 28829792 — Biomarker: IKBKB mRNA
Type: Predictive Biomarker (PRD)
Genes: IKBKB; IKKB
Study 28829792 — Biomarker: AK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: AK4; AK3; AK3L1
Study 11833048 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11833048 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 11833048 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 11833048 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11833048 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23415431 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23415431 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23415431 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 23415431 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21240901 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26143444 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17361529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8671551 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 1817621 — Biomarker: CENPJ mRNA
Type: Predictive Biomarker (PRD)
Genes: CENPJ; CPAP; LAP; LIP1
Study 22137075 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 29926695 — Biomarker: DCC mRNA
Type: Predictive Biomarker (PRD)
Genes: DCC; IGDCC1
Study 29926695 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 24530676 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 22228743 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15685250 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15685250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15685250 — Biomarker: NE
Type: Predictive Biomarker (PRD)
Study 9097708 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 12728539 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1414040 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2580179 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30569654 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 10453872 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 498720 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 498720 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24121064 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24121064 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24121064 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24121064 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2676257 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25770117 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25770117 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17576863 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1110481 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1110481 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 16019766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26209166 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22237871 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 9470169 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21774822 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12568942 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10563276 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30848023 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30848023 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17067837 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 3341527 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16283318 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 16283318 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 102114 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 29874805 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 24390777 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15924805 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8703644 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8703644 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31691462 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 31691462 — Biomarker: Platelet count response
Type: Surrogate Endpoint (SUR)
Study 28181131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12113380 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 17335405 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 17335405 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 3284943 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29446098 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22519866 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 8600628 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8440768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25635327 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21708185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16424784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25231677 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23652739 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 16433771 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3222154 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 31698359 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 31698359 — Biomarker: FABP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FABP4
Study 31698359 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28275830 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 14523272 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10801756 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 24241212 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30887731 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25524798 — Biomarker: CCND1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND1; BCL1; PRAD1
Study 25524798 — Biomarker: CDKN2A mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2A; CDKN2; MTS1
Study 25524798 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 11251037 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 29599478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19939723 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 11836044 — Biomarker: Connecting peptide
Type: Safety Biomarker (SAF)
Genes: AHSG; FETUA; PRO2743
Study 7538237 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 1632402 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17949394 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 25920709 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 25146067 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17464093 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 3289433 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31084985 — Biomarker: TIMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TIMP2
Study 31084985 — Biomarker: IGFBP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP7; MAC25; PSF
Study 31084985 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31084985 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28284500 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 18160344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8688986 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31196169 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 28639119 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 28639119 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 28639119 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 9709409 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2736920 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 15228134 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD