AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 18775846 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31714444 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 31714444 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 12360157 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12360157 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30392424 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30392424 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21162925 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17926468 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17926468 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28658163 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 22947547 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15342302 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15342302 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29877609 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29877609 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24679633 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 6262206 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 6262206 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31537574 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 19166565 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17084909 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9159562 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7958160 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23796685 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 17947224 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31802880 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17935545 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17935545 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11755954 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 25466655 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25466655 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25466655 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25466655 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2987294 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30217229 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26946962 — Biomarker: PRKCB mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKCB; PKCB; PRKCB1
Study 10451943 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29417761 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 25372381 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 18393008 — Biomarker: FGR mRNA
Type: Predictive Biomarker (PRD)
Genes: FGR; SRC2
Study 10493680 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 10493680 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 10493680 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2069776 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31013851 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31013851 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 19325997 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 19325997 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 6983315 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26997655 — Biomarker: Ataxin-3
Type: Pharmacodynamic Biomarker (PDY)
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 26997655 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 26997655 — Biomarker: Histone acetylation
Type: Pharmacodynamic Biomarker (PDY)
Study 24586256 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2239934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31473505 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16555941 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 16555941 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30106637 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 27777076 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20388201 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 30672383 — Biomarker: IGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF2; PP1446
Study 27059887 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 27059887 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 2642754 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 2642754 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 797258 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 797258 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30137547 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22496156 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 18815438 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 25671254 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 25671254 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 25671254 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10760337 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1996894 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27413123 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27413123 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 17121522 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 12692844 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 20609187 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10616845 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10616845 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 10616845 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8830827 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 30316147 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 20138267 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 12023995 — Biomarker: Nasal potential difference
Type: Pharmacodynamic Biomarker (PDY)
Study 18767577 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 6375603 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 31310354 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30028023 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 30028023 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 30028023 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 10583717 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31982847 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30896643 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30896643 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 25524125 — Biomarker: TNFRSF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1A; TNFAR; TNFR1
Study 25524125 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17214933 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 991103 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 30998121 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 28969431 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 27861335 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 27861335 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17596121 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 388398 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 16900233 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15039494 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11731186 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11731186 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11731186 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3815764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15893181 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15893181 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12668787 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 30126064 — Biomarker: ACTG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACTG1; ACTG
Study 30126064 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 28106354 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25582310 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 24016068 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 30304656 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17017821 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 12705366 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31043758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3747800 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27499378 — Biomarker: Urokinase plasminogen activator surface receptor
Type: Monitoring Biomarker (MOI)
Genes: PLAUR; MO3; UPAR
Study 18380954 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2197297 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15273192 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 10396713 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 7747715 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 2174950 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6769256 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29775437 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 24612081 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24612081 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15676171 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28406125 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28406125 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9227205 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 19214743 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12586255 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12586255 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10589275 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17701671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27681753 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 18946896 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31852125 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26266414 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 21617197 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 21617197 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21617197 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21617197 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14510339 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3533371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29385034 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15356075 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 15356075 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 8450399 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21901480 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15023882 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 11135381 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10399517 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10399517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7771954 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23512062 — Biomarker: LY96 mRNA
Type: Predictive Biomarker (PRD)
Genes: LY96; ESOP1; MD2
Study 23512062 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 22283900 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2455187 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8372519 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 28919201 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 25976467 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 25976467 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25976467 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25976467 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25976467 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 16402081 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 16402081 — Biomarker: NCS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: NCS1; FLUP; FREQ
Study 16402081 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 8398218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8398218 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31852268 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31852268 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27856142 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 30712901 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 27111542 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 21985070 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 30658660 — Biomarker: BMF mRNA
Type: Predictive Biomarker (PRD)
Genes: BMF
Study 30658660 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30658660 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 11708574 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11708574 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30688979 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27703563 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17898947 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17898947 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17898947 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15180973 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29924240 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 25557189 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 21541732 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 14675064 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14675064 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 27185685 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22157880 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20301021 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 17243915 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17243915 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 17243915 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 17243915 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17243915 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 9889429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27484763 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25807090 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 9649985 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2524386 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 11519700 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 11519700 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 27484507 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20022990 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19246793 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10715305 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 30497530 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30497530 — Biomarker: TMEM100 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMEM100
Study 30497530 — Biomarker: ALK
Type: Predictive Biomarker (PRD)
Genes: CD246; ALK1
Study 30497530 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16113791 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16113791 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 17237646 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 8848889 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31752042 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 30730541 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 28831241 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28831241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30535716 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 21183370 — Biomarker: SV2A mRNA
Type: Predictive Biomarker (PRD)
Genes: SV2A; KIAA0736; PSEC0174
Study 19859541 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 9678778 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 19122109 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19122109 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)