AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 29079475 — Biomarker: F7 mRNA
Type: Predictive Biomarker (PRD)
Genes: F7
Study 27418817 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 22246943 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20465146 — Biomarker: CFI mRNA
Type: Predictive Biomarker (PRD)
Genes: CFI; IF
Study 15732035 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 1657528 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27483130 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15848906 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 8738665 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8738665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2883677 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27098404 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16168734 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 12706640 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 12706640 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 24960665 — Biomarker: RHD mRNA
Type: Predictive Biomarker (PRD)
Genes: RHD
Study 21036891 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 21036891 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 2653621 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2653621 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31630035 — Biomarker: CBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CBX1; CBX
Study 26391131 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24259978 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study 20195183 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 7884951 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20638322 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 12100060 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 12100060 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 10791216 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29168044 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21054769 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8529777 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22753310 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 22753310 — Biomarker: CYP17A1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CYP17A1; CYP17; S17AH
Study 16954134 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26451761 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 9828907 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 9828907 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 24246119 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 19029469 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 19029469 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19029469 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19029469 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26579947 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 21317148 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3025927 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27098820 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27098820 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27098820 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24490888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22569236 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18823658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25544738 — Biomarker: CXADR mRNA
Type: Predictive Biomarker (PRD)
Genes: CXADR; CAR
Study 25544738 — Biomarker: CXCL13 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL13; BCA1; BLC; SCYB13
Study 17879532 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15536655 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 2757878 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18678578 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10336577 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29587831 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 29587831 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 22940462 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 6982626 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 28963290 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 22886490 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 22886490 — Biomarker: CD83 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD83
Study 22886490 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 22886490 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 17446997 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8737755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6741192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19920081 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11302475 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31370223 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25970229 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10685239 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 8596489 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 3155939 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17922939 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17922939 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30634204 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21841087 — Biomarker: TNC mRNA
Type: Predictive Biomarker (PRD)
Genes: TNC; HXB
Study 21841087 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 24875671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24875671 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 24875671 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 21978663 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 27789120 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23548455 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15152874 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 23774331 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15253739 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 2881320 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 30407354 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 28608398 — Biomarker: RUNX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX2; AML3; CBFA1; OSF2; PEBP2A
Study 28608398 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28608398 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22431415 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 21909502 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17519147 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 803203 — Biomarker: DMTN mRNA
Type: Predictive Biomarker (PRD)
Genes: DMTN; DMT; EPB49
Study 28502503 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28502503 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26134988 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26134988 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 23375799 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1728930 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22208555 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 22208555 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 22208555 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 20466742 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 10963288 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 12859157 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26489028 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24338058 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 658870 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31096728 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 15786695 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 17244442 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10371654 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 1894888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31502856 — Biomarker: GSS mRNA
Type: Predictive Biomarker (PRD)
Genes: GSS
Study 10443671 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 7847975 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 7658777 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 79709 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29150457 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 26225995 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12441211 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7723950 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6779303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16914412 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16914412 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10930321 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19213339 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 26579854 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 19082693 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19082693 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19082693 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 19082693 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 19082693 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11975770 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2894161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18294500 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 811427 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 811427 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26323018 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 12592245 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6119103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26981576 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26981576 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26981576 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 22429436 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 12373041 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9833600 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9833600 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 335687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26324372 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23490328 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16428576 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15213563 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30601429 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 30601429 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30408810 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2480626 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 1107462 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 25436213 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25436213 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 8781630 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 29479010 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29479010 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26965492 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25151031 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12148173 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 17660602 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15876831 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 8151107 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 26672090 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 26672090 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22169113 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 22169113 — Biomarker: DMBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DMBX1; MBX; OTX3; PAXB
Study 11783155 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 11783155 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 11783155 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 7001242 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 26393848 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26393848 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2655452 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2655452 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31518058 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19646193 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9773737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21568083 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 14999611 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12219065 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12219065 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12219065 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25733651 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23985261 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 10685792 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10685792 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 10685792 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 10685792 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23572413 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24399553 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 9010695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30977033 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11104737 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 1735586 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1735586 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28625242 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 23561971 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 16636488 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2069791 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20920276 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 10499778 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 1758713 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21305271 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21305271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19667239 — Biomarker: RHD mRNA
Type: Predictive Biomarker (PRD)
Genes: RHD
Study 15085385 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 15085385 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 15085385 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 11346128 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 31639060 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31639060 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29354994 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 11099365 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2908820 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12398236 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17010149 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 17010149 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17010149 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10417864 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25293351 — Biomarker: IGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF2; PP1446
Study 22089249 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20832062 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 17071935 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 7581970 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 7581970 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 2372011 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25893544 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25893544 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25893544 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)