AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31640647 — Biomarker: Beta-secretase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: BACE1; BACE; KIAA1149
Study 18382267 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18382267 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18382267 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18382267 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 12004637 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7806038 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 30379222 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10687884 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26342472 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 24712378 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24712378 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22668852 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17569128 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 15305694 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9794107 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 21161264 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19109444 — Biomarker: FST mRNA
Type: Predictive Biomarker (PRD)
Genes: FST
Study 27664457 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 27664457 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 21880242 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21880242 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19662998 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19662998 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 17536872 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17536872 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9868668 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15617457 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8342904 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 8342904 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 8342904 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 27575024 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 27575024 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 11869846 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 20934731 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16461044 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16461044 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 28464211 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 28464211 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28464211 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 25653079 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 25172379 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25172379 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2466024 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24791863 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22331829 — Biomarker: ABCG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 22331829 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 22331829 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 22331829 — Biomarker: MYLIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MYLIP; BZF1; IDOL; BM-023; PP5242
Study 22331829 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 22331829 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 22331829 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17222115 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15804151 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 12584830 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12584830 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12584830 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30706439 — Biomarker: LARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LARS1; KIAA1352; LARS
Study 28314866 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 9820611 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 20130074 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 24773166 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 22932119 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 17632760 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17632760 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25039804 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28279484 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 26164786 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21641636 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 21641636 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 21641636 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 20154337 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18772641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14870884 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17121590 — Biomarker: Urine free cortisol
Type: Surrogate Endpoint (SUR)
Study 6272242 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29633238 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 29633238 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 29633238 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 29633238 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 25889643 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23757457 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 21860572 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 18192039 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31420055 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 29415828 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25153575 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 3072178 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22114899 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22114899 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22114899 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22114899 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18609065 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 10996351 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 10996351 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 7013868 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 16449211 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20118486 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8267058 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8267058 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 6129077 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31451249 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30063644 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12952369 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19029264 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 25943394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23052515 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11807305 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10072411 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31228055 — Biomarker: SMPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMPD1; ASM
Study 31228055 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 31228055 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 21754985 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 18697216 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 8026195 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 21839983 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 16814411 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27522514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23506731 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 3537462 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31419322 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 24019539 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 8200006 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 2965631 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 28860599 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12124550 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31013226 — Biomarker: PTGS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGS1; COX1
Study 30158152 — Biomarker: Sodium/hydrogen exchanger 3
Type: Safety Biomarker (SAF)
Genes: SLC9A3; NHE3
Study 15850130 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10568115 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 1868270 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 24047244 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24047244 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21034619 — Biomarker: ABCD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCD1; ALD
Study 17437965 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 10461824 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28124127 — Biomarker: HK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: HK2
Study 28124127 — Biomarker: PDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PDK4; PDHK4
Study 19773751 — Biomarker: EZH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EZH2; KMT6
Study 19773751 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 9217714 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25395071 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 25395071 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7542134 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 17163810 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 9640068 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30676622 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 29975403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29975403 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 22151064 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 8136443 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 24228535 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8500859 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8500859 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18593491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31348053 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21487251 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23423270 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 23423270 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 11061773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8861677 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 1739360 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 6135439 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26132079 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 24256677 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 1534664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1534664 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30842257 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27339848 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22721353 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 8784219 — Biomarker: CLYBL mRNA
Type: Predictive Biomarker (PRD)
Genes: CLYBL; CLB
Study 17489939 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 10867779 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 25468986 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15765440 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 12422622 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10482930 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30845690 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30845690 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 19940281 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8092508 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18433023 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 21636796 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11309556 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 11309556 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 11309556 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 18640769 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 12514660 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8807058 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7989477 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25925220 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 19306961 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31089709 — Biomarker: TMPRSS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMPRSS13; MSP; TMPRSS11
Study 26330144 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 19725253 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 17964975 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30394960 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27710139 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23940575 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28109298 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17407649 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 17407649 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 1826239 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28421567 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12630974 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 10866717 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4044293 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 4044293 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 4044293 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11230472 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 18276664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25057105 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25057105 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 25057105 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23083772 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 23083772 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29511019 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29511019 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29511019 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29511019 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9394987 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 21519749 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21519749 — Biomarker: Complement C4
Type: Monitoring Biomarker (MOI)
Study 27941937 — Biomarker: KLRC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRC1; NKG2A
Study 15545978 — Biomarker: NRG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study 12860491 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12860491 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12860491 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29040226 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 16636233 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30571546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19590021 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 3330989 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28058714 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 24490577 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21328025 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8979144 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 8979144 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8979144 — Biomarker: Vitamin K-dependent protein C
Type: Safety Biomarker (SAF)
Genes: PROC
Study 6823952 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15325416 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 11216930 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8382234 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23136031 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23136031 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 19996424 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 9005975 — Biomarker: HHEX mRNA
Type: Predictive Biomarker (PRD)
Genes: HHEX; HEX; PRH; PRHX