AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 26891216 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2361813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25567119 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 19660610 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19660610 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9333106 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 25888571 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 25888571 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24021286 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22776634 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31502893 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21392600 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21392600 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19151304 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15525879 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28292340 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26178497 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26178497 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26879829 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23086244 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15752371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30342855 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 27255504 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 8707361 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8707361 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 24655490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24655490 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 12011706 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 341950 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27788498 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 23910702 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22194781 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9495661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28277811 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 7757308 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11527140 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31411375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22746245 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 21684478 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 21684478 — Biomarker: PNO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PNO1
Study 18689695 — Biomarker: TCF7L2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCF7L2; TCF4
Study 18689695 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12846597 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 12846597 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 12846597 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 58269 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31068063 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 20075143 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 15767770 — Biomarker: DMA mRNA
Type: Predictive Biomarker (PRD)
Genes: DMA; HLA-DMA; hCG_2001572
Study 21318572 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 1488936 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20102918 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31074198 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 31074198 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21041811 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16306540 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 788749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31881340 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30429032 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 30429032 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 27440535 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 24432999 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 24432999 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 8970830 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 1279290 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3905414 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31060545 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26662208 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 22400810 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10509772 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 27761987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25591756 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 25591756 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 17444309 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 12450060 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29218707 — Biomarker: ABCG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 29218707 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27616217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27616217 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12875474 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10375185 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 25371053 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17998780 — Biomarker: PLG mRNA
Type: Predictive Biomarker (PRD)
Genes: PLG
Study 68285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31782931 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 31782931 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 31782931 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31782931 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 25560820 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29470249 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 18387159 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 20043182 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 2021446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25016922 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 19843060 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 19843060 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 17495570 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11940299 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 30848558 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26803169 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17660482 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 1599635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10848660 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22504093 — Biomarker: CTLA4
Type: Predictive Biomarker (PRD)
Genes: CD152; CD; GSE; CTLA-4
Study 19796735 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25190442 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18245544 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 18245544 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 12574925 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27543065 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22546175 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22546175 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 24911076 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 17178634 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 17178634 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 17178634 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 17178634 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 17178634 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 12161090 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7887382 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7887382 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22221427 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19224761 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 17301297 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23564755 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 16140028 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 9363868 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study 1306735 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 20835747 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10501150 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 28033254 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 28033254 — Biomarker: BCL2A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCL2A1; BCL2L5; BFL1; GRS; HBPA1
Study 28033254 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 20185655 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18035201 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 10070128 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6112386 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28006059 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 26338693 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19434784 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 28135225 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 23565660 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 23565660 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 7867225 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15860686 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9347069 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 7685176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19029083 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19029083 — Biomarker: FGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF2; FGFB
Study 19029083 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8777296 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 8777296 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 1806610 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31348579 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 31348579 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 21863237 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21863237 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 14978184 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 11230885 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 9737645 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2537563 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18439662 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 17062966 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 17062966 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22532639 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22532639 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18585837 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 18585837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18585837 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8862477 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 22564753 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22564753 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 22564753 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 22564753 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 22564753 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 17671159 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 16536310 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9445297 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24028942 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24028942 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22319896 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9783499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7841749 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 7841749 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3074295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31704275 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 24633624 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28817370 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 16753687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16753687 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16753687 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15484298 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 27389172 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 16941030 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16941030 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10935770 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 19965781 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 12401635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10087420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22781558 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 20471117 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17260161 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17260161 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 14696754 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25670360 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16478755 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 11157334 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26654125 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 9258756 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25658671 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 23829776 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10543320 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10543320 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30249203 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27481309 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 15963095 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 1834765 — Biomarker: PHLPP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PHLPP1; KIAA0606; PHLPP; PLEKHE1; SCOP
Study 20692141 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 20692141 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 17584562 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9648966 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 21565956 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12830441 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12830441 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 20525705 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9579244 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7714108 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 21282282 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17200216 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27686971 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22682335 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 11990445 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 1644080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26027619 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 26027619 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21744143 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 21744143 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2192529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 353597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27901186 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27901186 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 29862411 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29862411 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20833991 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20833991 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20833991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19636365 — Biomarker: TLR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR7; UNQ248/PRO285
Study 11410114 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1