AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 2737225 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2737225 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 28151719 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 28151719 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 27132448 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2376846 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25752740 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12632615 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 12632615 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30795773 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 30795773 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17569144 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2197046 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 31539077 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 31539077 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 27713892 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24469620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30885375 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 30885375 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27111221 — Biomarker: CHL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHL1; CALL
Study 27111221 — Biomarker: NELL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NELL1; NRP1
Study 27111221 — Biomarker: GDF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GDF1
Study 27111221 — Biomarker: ARHGEF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARHGEF4; KIAA1112
Study 27111221 — Biomarker: ITGA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGA4; CD49D
Study 27111221 — Biomarker: POLR2B mRNA
Type: Predictive Biomarker (PRD)
Genes: POLR2B
Study 27111221 — Biomarker: CYP1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1B1
Study 27111221 — Biomarker: miR-9
Type: Safety Biomarker (SAF)
Study 27111221 — Biomarker: miR-124
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21219121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20648004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15127090 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11772908 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11772908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29105594 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 25373834 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23929932 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23929932 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 1448789 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27109947 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22873531 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15799919 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15755826 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15755826 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 6828530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21979301 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 19712493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25108907 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 19202954 — Biomarker: ABCD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCD2; ALD1; ALDL1; ALDR; ALDRP
Study 12920842 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 27463 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30071142 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23358929 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 9234024 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 29216937 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9587911 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 7912539 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2645808 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18444872 — Biomarker: TLR9
Type: Predictive Biomarker (PRD)
Genes: CD289
Study 12574791 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25199862 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 9459398 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9459398 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30427997 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 30427997 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30427997 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23743804 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20883456 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 14596683 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 3882125 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3882125 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26843092 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 20511163 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 16426710 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11069364 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8616014 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8616014 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 25181492 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25181492 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22112608 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22112608 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9143862 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8565538 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 1827013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26264425 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 9059563 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23065684 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 18398147 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29763709 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12580941 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 29402752 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 16152828 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 16152828 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 10100579 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10100579 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 14754569 — Biomarker: DDT mRNA
Type: Predictive Biomarker (PRD)
Genes: DDT
Study 7604802 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31068270 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study 27817944 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27817944 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17468493 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30135020 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20172704 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17490960 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31762443 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 25886327 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15572894 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 11339466 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2483828 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18434722 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8837186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21890793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12584831 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 21849081 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 19596586 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17012630 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 21080844 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 11158415 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9550632 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29344579 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 25850881 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21242819 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 21242819 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 10686961 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 10686961 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10686961 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8662400 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8662400 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8662400 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8662400 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31863809 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 30683137 — Biomarker: NANOS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS3; NOS3
Study 1328366 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15695780 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 1866057 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 25509255 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 25509255 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7105431 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 8651535 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11498655 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11498655 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7994449 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 7994449 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25006405 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 25006405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21617914 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 12888702 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8314497 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22093035 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21130382 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 15576394 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 7623902 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2717986 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 31415033 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 31415033 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 31415033 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26116458 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23869233 — Biomarker: LIPA mRNA
Type: Predictive Biomarker (PRD)
Genes: LIPA
Study 16461311 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16461311 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 16398654 — Biomarker: ZFP36 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 12829196 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10365634 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 8963484 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21697535 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 21697535 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21697535 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16229059 — Biomarker: GYPC mRNA
Type: Predictive Biomarker (PRD)
Genes: GYPC; GLPC; GPC
Study 16229059 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 10869264 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10869264 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 10869264 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 1413921 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6273009 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31542082 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24600231 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24600231 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17697903 — Biomarker: MERTK mRNA
Type: Predictive Biomarker (PRD)
Genes: MERTK; MER
Study 9506323 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2525975 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16312927 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 2073336 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 18433946 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18433946 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14513232 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 11320561 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11320561 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study 24060022 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18753749 — Biomarker: PLB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLB1; PLB
Study 2864936 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24818590 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 7924784 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7924784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20039090 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 7845310 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31865785 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 24533792 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 23108883 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 19734176 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 26056191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18547692 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 15849842 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 12585167 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 12585167 — Biomarker: STIL mRNA
Type: Predictive Biomarker (PRD)
Genes: STIL; SIL
Study 12585167 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 22692704 — Biomarker: Angiopoietin-1
Type: Monitoring Biomarker (MOI)
Genes: ANGPT1; KIAA0003
Study 22692704 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 11503113 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9560874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24045856 — Biomarker: OSM mRNA
Type: Predictive Biomarker (PRD)
Genes: OSM
Study 20130487 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9919476 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30626263 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 27085343 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25616355 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25616355 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 11018567 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26476151 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18413705 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 10911771 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27888561 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 26276914 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24108261 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21368663 — Biomarker: SLC4A7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC4A7; BT; NBC2; NBC2B; NBC3; NBCn1; SBC2; SLC4A6
Study 18199130 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 18199130 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18199130 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 14662284 — Biomarker: CTNS mRNA
Type: Predictive Biomarker (PRD)
Genes: CTNS
Study 1395760 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 1395760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28257107 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19651872 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19651872 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 19651872 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 25871017 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25871017 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21142752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14707555 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 14707555 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8996134 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29750266 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 25607338 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 25607338 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25607338 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 19077833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)