AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 11108899 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11108899 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 14996776 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14996776 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11475557 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 7594429 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7594429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28347540 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28347540 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21156702 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 19717506 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19717506 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17451140 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25389641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21169060 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 17062685 — Biomarker: ABCG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 12712781 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11107075 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 2989349 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2989349 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25453518 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 20974575 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20974575 — Biomarker: Undetectable plasma HIV RNA
Type: Surrogate Endpoint (SUR)
Study 10594426 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31836434 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31836434 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31563038 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 16492207 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16492207 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22555328 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 17805075 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30418098 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23416718 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16923247 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 16923247 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10424316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30886898 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 28146658 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 24052416 — Biomarker: MHC class I polypeptide-related sequence A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MICA; PERB11.1
Study 17021352 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 9527746 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7888516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31567592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31601989 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 21084154 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12169332 — Biomarker: CLN5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLN5
Study 9666940 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20974511 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26160062 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7490141 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 2258874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27956016 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 26220945 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31145173 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31145173 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30286558 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22464581 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15895275 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9705036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31075662 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29078966 — Biomarker: PCSK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK5; PC5; PC6
Study 20072036 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17919233 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 23684482 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 23684482 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 8553350 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 21180216 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15246912 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15246912 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 3289804 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23497111 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18343702 — Biomarker: FAM53B mRNA
Type: Predictive Biomarker (PRD)
Genes: FAM53B; KIAA0140; SMP
Study 9167019 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8193732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31350967 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 31350967 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26179985 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19061063 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12091806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8946597 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 8946597 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30614153 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 23385306 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20555369 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20555369 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20555369 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30868641 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 17974536 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 12115318 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 31685037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31544547 — Biomarker: ADAM17 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM17; CSVP; TACE
Study 26011257 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 29538682 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29538682 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 14605954 — Biomarker: MFF mRNA
Type: Predictive Biomarker (PRD)
Genes: MFF; C2orf33; AD030; AD033; GL004
Study 10793494 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10793494 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 25837212 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25837212 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20012799 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2189288 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 29799307 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 14963702 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 14963702 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 14963702 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11588947 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9973671 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 9973671 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2647645 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26465872 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 26465872 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21786539 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19190515 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study 9268956 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 31693128 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 9628067 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9628067 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30998400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30998400 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28337880 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10719136 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 28605557 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26271344 — Biomarker: SLC22A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A1; OCT1
Study 23167843 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 20019197 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18657960 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18657960 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16176140 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 16176140 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10414119 — Biomarker: LTK mRNA
Type: Predictive Biomarker (PRD)
Genes: LTK; TYK1
Study 24759301 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24759301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16086615 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 7862469 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30439786 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19247267 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1532382 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 29968137 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26401577 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14687524 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 31949012 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 20692602 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17985199 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17985199 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17985199 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 10353670 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31834125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10993641 — Biomarker: MYCN mRNA
Type: Predictive Biomarker (PRD)
Genes: MYCN; BHLHE37; NMYC
Study 8366413 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25498992 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20031392 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23346948 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 16391584 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9158047 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9158047 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 8198036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8198036 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 30850828 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30850828 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17029616 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 7880659 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27041480 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12941993 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12941993 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8203335 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17225370 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23619509 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 23619509 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 16094059 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12108334 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8646822 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 17367446 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 26463007 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25551810 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20724766 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20724766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14568987 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 27354043 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19841339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16766774 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16766774 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 18364384 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1774375 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26728913 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 22672707 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22672707 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 22672707 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8352699 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 3669200 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29738271 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 24122191 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24122191 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 15465071 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 9509446 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24189367 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 19553647 — Biomarker: TCF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCF3; BHLHB21; E2A; ITF1
Study 19553647 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 10789609 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10789609 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18412958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20722531 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 6851273 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17951625 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 28845931 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 25727806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24074879 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24074879 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 7932809 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7932809 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27063478 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 20689824 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20689824 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 23593417 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 23593417 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 2455153 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21998206 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 21998206 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 16549905 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10959787 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 2821151 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29651953 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14765284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12921618 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16249145 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 2852389 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23549644 — Biomarker: SERPINA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 23549644 — Biomarker: APEX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 9039510 — Biomarker: SERPINA7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA7; TBG
Study 25790670 — Biomarker: BTLA mRNA
Type: Predictive Biomarker (PRD)
Genes: BTLA
Study 25790670 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 25790670 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25790670 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25790670 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 25790670 — Biomarker: CD24 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD24; CD24A
Study 9643623 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21577010 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11273498 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 1394811 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 9833601 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30622317 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21108204 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15998354 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15998354 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9812915 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9812915 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8043704 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 29119418 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU