AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 19363237 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19363237 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 24705588 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 24705588 — Biomarker: ENPP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ENPP1; M6S1; NPPS; PC1; PDNP1
Study 15840994 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17161670 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 2888547 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 2847454 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 31353479 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30032171 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28791477 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 26043025 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study 26043025 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 26043025 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 19104004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24152821 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16673837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10865417 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 14710262 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26606990 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9849385 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31605208 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31605208 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27522605 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25929560 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 25929560 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 25929560 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 16079649 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 949102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25227967 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21777013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11207321 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 26699871 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 14521759 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15642811 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 12146001 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 7768238 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 19203712 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15131531 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 3280484 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29908345 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8469785 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8469785 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 30713722 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29203893 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29203893 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 29203893 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 24067745 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 24067745 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 23469595 — Biomarker: STC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STC1; STC
Study 20038536 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20038536 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 20038536 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 20038536 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 2536516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30944162 — Biomarker: CD1C mRNA
Type: Predictive Biomarker (PRD)
Genes: CD1C
Study 30944162 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 30944162 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22099238 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19440788 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31005993 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27857631 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 20965712 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17346628 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2238169 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 8535669 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 25867865 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 19548028 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29320587 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 27097354 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15080821 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 9249114 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31703936 — Biomarker: CTBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CTBS; CTB
Study 31703936 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 18389900 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11524351 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8395761 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8395761 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25461690 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 21298358 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14610236 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14610236 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11391341 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8280188 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8280188 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 9857536 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30659811 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17076980 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17076980 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17076980 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17076980 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9540024 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 7972294 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7972294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2585731 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17622942 — Biomarker: Cathepsin S
Type: Pharmacodynamic Biomarker (PDY)
Genes: CTSS
Study 17622942 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 17622942 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 17622942 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 17622942 — Biomarker: IL1R1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1R1; IL1R; IL1RA; IL1RT1
Study 17622942 — Biomarker: IL12RB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL12RB2
Study 17622942 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 12095383 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2029180 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 31474119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31474119 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22832540 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 19779025 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 8608488 — Biomarker: TRO mRNA
Type: Predictive Biomarker (PRD)
Genes: TRO; KIAA1114; MAGED3
Study 31383503 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31383503 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25887557 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9888867 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 9888867 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 9888867 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 9888867 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 7718754 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7718754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22748098 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15906030 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 30536081 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 30239794 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23137494 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23137494 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 7807658 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7807658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7807658 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2947465 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25818388 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21868617 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21868617 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11755325 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18502107 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27471815 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 27471815 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 25816720 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25816720 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 25816720 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19733721 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15262827 — Biomarker: SLC52A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC52A2; GPR172A; PAR1; RFT3
Study 7978091 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28460544 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 25441397 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25441397 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 25441397 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 22692637 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 10206309 — Biomarker: Survival motor neuron protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 10829909 — Biomarker: Beta-N-acetylhexosaminidase
Type: Safety Biomarker (SAF)
Genes: OGA; HEXC; KIAA0679; MEA5; MGEA5
Study 31222188 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25066012 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 23363492 — Biomarker: SLBP mRNA
Type: Predictive Biomarker (PRD)
Genes: SLBP; HBP
Study 21876296 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 9407447 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27801789 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27801789 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 27801789 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 23683751 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 23174584 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 23174584 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23174584 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23132262 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31451013 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 20673141 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 20673141 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23510037 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29193877 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23449351 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23449351 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 23449351 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22281801 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 30569416 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 25801942 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 19107948 — Biomarker: SGTA mRNA
Type: Predictive Biomarker (PRD)
Genes: SGTA; SGT; SGT1
Study 12684305 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 9365968 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1526090 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26433318 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 15084178 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8004831 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30225992 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26436207 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24228894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10513866 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26189647 — Biomarker: SHC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SHC1; SHC; SHCA
Study 25014766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20594464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11818701 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11818701 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29126212 — Biomarker: CYP7B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP7B1
Study 19050053 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 6542243 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25936338 — Biomarker: EMP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EMP1; B4B; TMP
Study 9462904 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 8778745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1104284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31266035 — Biomarker: DCC mRNA
Type: Predictive Biomarker (PRD)
Genes: DCC; IGDCC1
Study 26265231 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 29625605 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 16213293 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12455359 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 7558928 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7558928 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7558928 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31464773 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22912941 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22912941 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22912941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15573395 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 10430979 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10430979 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10430979 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31371115 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 20585102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17369808 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 12193097 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9860785 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 4471965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11135797 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30912414 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30912414 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 1648142 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 30945320 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 30119145 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8961074 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8961074 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2509064 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26077768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21663428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11075988 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11075988 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10484572 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 8835619 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8835619 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28054389 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 28054389 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 23921777 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23921777 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21292760 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8034203 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 786673 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25863779 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG