AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 16192502 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9118847 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29672897 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 15752945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29277856 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 29277856 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21742098 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 15001605 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 11709513 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 11709513 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2885116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30824268 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30824268 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12148574 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 2454514 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2454514 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 2454514 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 25082954 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 25082954 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14965840 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 8223829 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8594515 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2015119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29850782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16644783 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11445622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8061995 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16292207 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16292207 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 16292207 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 16292207 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29275919 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29275919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20007932 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10527181 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7669481 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 7669481 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7669481 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 7669481 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7669481 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31531960 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25502511 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19954719 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 19954719 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17578464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15187493 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15187493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27687355 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 21056810 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9534963 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31229240 — Biomarker: CSF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF1
Study 21971662 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21971662 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11597824 — Biomarker: TPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH1; TPH; TPRH; TRPH
Study 22104547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31813058 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16531899 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8466715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21616975 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 10890026 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10890026 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 9100582 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20863951 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20863951 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15944845 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12883404 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 30325018 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 30325018 — Biomarker: TBC1D4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TBC1D4; AS160; KIAA0603
Study 22971356 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14643816 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 19194995 — Biomarker: ENPP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ENPP2; ATX; PDNP2
Study 29433850 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29433850 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 29433850 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 24875610 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 24875610 — Biomarker: GLS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS2; GA
Study 24875610 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17919718 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 2143459 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 2143459 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2143459 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11549632 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7509244 — Biomarker: DDR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 7509244 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21958782 — Biomarker: BAX mRNA
Type: Predictive Biomarker (PRD)
Genes: BAX; BCL2L4
Study 21958782 — Biomarker: BAD mRNA
Type: Predictive Biomarker (PRD)
Genes: BAD; BBC6; BCL2L8
Study 18328363 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22762844 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20164395 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 18058736 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 17617280 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14707154 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25924880 — Biomarker: LSR mRNA
Type: Predictive Biomarker (PRD)
Genes: LSR; ILDR3; LISCH
Study 19304119 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17805035 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15657405 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 11959402 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 8815124 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 21809148 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16882622 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 9042095 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9042095 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31695136 — Biomarker: FGR mRNA
Type: Predictive Biomarker (PRD)
Genes: FGR; SRC2
Study 28474088 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24730717 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 26999011 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 24786356 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 24786356 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24786356 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12594633 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 11783334 — Biomarker: GRN mRNA
Type: Predictive Biomarker (PRD)
Genes: GRN
Study 20430458 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 388400 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 388400 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22409922 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 8695129 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8695129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12185449 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12185449 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 1725543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23475701 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23258574 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 18060746 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 11322256 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6809420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24165361 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 19700435 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19700435 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 19700435 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study 8557061 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 26242287 — Biomarker: KCNN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNN3; K3
Study 18173921 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 18173921 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30946262 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19592223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17479256 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 11526473 — Biomarker: TPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH1; TPH; TPRH; TRPH
Study 2015168 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30639574 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28490464 — Biomarker: EGR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: EGR3; PILOT
Study 28490464 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28490464 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26264470 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17573988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15164437 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9451748 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15374271 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2828820 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 24244295 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 20378921 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17213004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10958764 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 10958764 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23635681 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 23635681 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9741509 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28570317 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25928457 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25928457 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23849306 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 8349379 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 18002724 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 18002724 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 26994230 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15844838 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 10579275 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26259617 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11566640 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 9624696 — Biomarker: CLC mRNA
Type: Predictive Biomarker (PRD)
Genes: CLC; LGALS10; LGALS10A
Study 24828094 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24828094 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 23174063 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18614402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12614526 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 10651119 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 31578564 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 17991651 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17991651 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30544335 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 30544335 — Biomarker: IL13
Type: Predictive Biomarker (PRD)
Genes: P600; IL-13; ALRH; BHR1; MGC116786; MGC116788; MGC116789
Study 25022834 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18702964 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18574557 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 18574557 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9309995 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24700403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15584487 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 15584487 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 26171933 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 26171933 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 10508227 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26031737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15389235 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11177086 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31313942 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 28341525 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 19563648 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24576513 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22321661 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17923611 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 6106884 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6106884 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 6106884 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 2556725 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2556725 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 31175001 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 15494230 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 11341354 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 11341354 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 9004097 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28605730 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22996370 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25887358 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15499697 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 3307795 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27401564 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21610201 — Biomarker: FFAR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FFAR1; GPR40
Study 17980667 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12483717 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12483717 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26685869 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26685869 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26685869 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26685869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22495174 — Biomarker: DRD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD1
Study 26856247 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8006397 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 29241576 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16214329 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 16214329 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 16214329 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11425671 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 18998824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12514663 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12514663 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1338083 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1338083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2580171 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18519835 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12915670 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)