AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31187518 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 25886569 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16019923 — Biomarker: SH3PXD2A mRNA
Type: Predictive Biomarker (PRD)
Genes: SH3PXD2A; FISH; KIAA0418; SH3MD1; TKS5
Study 27854209 — Biomarker: GNE mRNA
Type: Predictive Biomarker (PRD)
Genes: GNE; GLCNE
Study 18692637 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14967869 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 14967869 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 11069375 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 4019261 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 31200819 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 27543984 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 23356491 — Biomarker: LTB4R mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 8473716 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2951158 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 28938434 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 17321924 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17321924 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27826127 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26115878 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24033362 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15919846 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8970468 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16439498 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7401203 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 6601746 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 22055480 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10340839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11324827 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11324827 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 31927325 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24503784 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 10532693 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10532693 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6998274 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 23149383 — Biomarker: PLB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLB1; PLB
Study 22218098 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23011680 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2929629 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29703040 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20109208 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15918622 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 12558577 — Biomarker: SULT1A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SULT1A3; STM
Study 9417493 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29773717 — Biomarker: Serine/threonine-protein kinase STK11
Type: Safety Biomarker (SAF)
Genes: STK11
Study 29773717 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 29773717 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 27416024 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27416024 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18303470 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 10414911 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10414911 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 8358504 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 29282929 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 18550935 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1673587 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30801699 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25070347 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15066470 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 7825744 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 3240842 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21908159 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 12717397 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12717397 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 12717397 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 8813840 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1566165 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2547950 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2547950 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26480553 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 15279041 — Biomarker: TNR mRNA
Type: Predictive Biomarker (PRD)
Genes: TNR
Study 9003214 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8305125 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8305125 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 8305125 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 22081005 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20171410 — Biomarker: CBLC mRNA
Type: Predictive Biomarker (PRD)
Genes: CBLC; CBL3; RNF57
Study 18165396 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8140940 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28626213 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29735470 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21180368 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 8628597 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 8628597 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8628597 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30048057 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 25277457 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22368149 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 21142632 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 216027 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31059955 — Biomarker: SLC2A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A1; GLUT1
Study 31059955 — Biomarker: Osteopontin
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SPP1; BNSP; OPN; PSEC0156
Study 31059955 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 31059955 — Biomarker: Hypoxia-inducible factor 1-alpha
Type: Predictive Biomarker (PRD)
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 27893331 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27893331 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18931824 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 18931824 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 18931824 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11060828 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21607954 — Biomarker: SLC15A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC15A1; PEPT1
Study 2853227 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27605969 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27605969 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27605969 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27605969 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 21150554 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 10702178 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 8397997 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12732401 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19890262 — Biomarker: High-frequency oscillations
Type: Pharmacodynamic Biomarker (PDY)
Study 18477227 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7232842 — Biomarker: MERTK mRNA
Type: Predictive Biomarker (PRD)
Genes: MERTK; MER
Study 17904975 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 9676035 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 9676035 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 9676035 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 30305054 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26248323 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18496261 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12713062 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26702629 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 17559725 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17559725 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23024190 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25850975 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25850975 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25850975 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25850975 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19271112 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17298711 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10714841 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 30864824 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 18307373 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 17000242 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8948303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1746414 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1746414 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21791142 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 19383589 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12492626 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12492626 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6193350 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21833000 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16946455 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10677399 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30371800 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26690356 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26690356 — Biomarker: SERPINF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINF1; PEDF; PIG35
Study 20217128 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 17351370 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17351370 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17351370 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2496213 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2496213 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 19417877 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 27550085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22802308 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 19874198 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7747819 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 23376799 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 21992121 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9370387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30923022 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 29277895 — Biomarker: ACKR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACKR3; CMKOR1; CXCR7; GPR159; RDC1
Study 29277895 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29277895 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 29277895 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25403681 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 24857100 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24857100 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24857100 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17953788 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 11778280 — Biomarker: HLF mRNA
Type: Predictive Biomarker (PRD)
Genes: HLF
Study 30453477 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 12918548 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 1290331 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 6721124 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 30421439 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21784372 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21784372 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9226601 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 22321279 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 22321279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19950759 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17101637 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30558758 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 25880052 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25880052 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25880052 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11254817 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29441973 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 29441973 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29441973 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 29441973 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24726635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16388832 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6381968 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 6381968 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 6381968 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 6609268 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 15886721 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15886721 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 14989068 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 10834778 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 26282062 — Biomarker: PLXNA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 20609215 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 1974394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10449028 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 10449028 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6818806 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 31262379 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 9868121 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12036640 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24560365 — Biomarker: MOXD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MOXD1; MOX; UNQ2493/PRO5780
Study 24560365 — Biomarker: ELK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELK3; NET; SAP2
Study 10589001 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 1836339 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 1836339 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 1836339 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1836339 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 25153538 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 17657599 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8067834 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 3051878 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28874797 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 14735556 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23082142 — Biomarker: AMHR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMHR2; AMHR; MISR2
Study 23082142 — Biomarker: VEGFC mRNA
Type: Predictive Biomarker (PRD)
Genes: VEGFC
Study 23082142 — Biomarker: SERPINE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINE2; PI7; PN1
Study 14985991 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 24231014 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25293882 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25293882 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 25293882 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 17388753 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 29284500 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 3120436 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24042066 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 21034646 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 30590353 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP