AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31404106 — Biomarker: CALD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CALD1; CAD; CDM
Study 28306591 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21701421 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 27866517 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 23327958 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23327958 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9196161 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 1542854 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 1542854 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9556142 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 30595477 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29229110 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 25367164 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 20945064 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 22291076 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 9856918 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2214868 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31325257 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 25552367 — Biomarker: MCAM mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAM; MUC18
Study 30224319 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18922117 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 18922117 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15797962 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 8594954 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26299229 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3234516 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8614419 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3027267 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24579221 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 7616988 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24987193 — Biomarker: C-C motif chemokine 4
Type: Monitoring Biomarker (MOI)
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 24987193 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 1941407 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 30535871 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30535871 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30535871 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30535871 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29030697 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20381870 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 20381870 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 20381870 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 20381870 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 20381870 — Biomarker: TLR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR3
Study 20381870 — Biomarker: HTRA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HTRA1; HTRA; PRSS11
Study 15798915 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 12461401 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 12461401 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 10757273 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10757273 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29960810 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25137874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20146169 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17909315 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 16184581 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26859236 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 26859236 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 11817991 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8785399 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29121350 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 24565591 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15247107 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 28011757 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 17561009 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11795345 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9732298 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 3054641 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 28319586 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 28319586 — Biomarker: Macrophage inflammatory protein 1-alpha
Type: Monitoring Biomarker (MOI)
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 28319586 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 28319586 — Biomarker: CCR2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCR2; CMKBR2
Study 28319586 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 28319586 — Biomarker: CXCR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR2; IL8RB
Study 14993506 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 2944924 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 24674975 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17278979 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 17278979 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 639430 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30985725 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 30985725 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 29911792 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26228672 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11405833 — Biomarker: MAX mRNA
Type: Predictive Biomarker (PRD)
Genes: MAX; BHLHD4
Study 9210608 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 7957341 — Biomarker: SLC25A20 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A20; CAC; CACT
Study 11340365 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 9175051 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 9175051 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 30613057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27005766 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31706345 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 22541418 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10729387 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 28627930 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28627930 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14742367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10967152 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 22590530 — Biomarker: C6orf15 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6orf15; STG; UNQ1840/PRO3566
Study 18957124 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10648315 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31831364 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 30600702 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30600702 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30600702 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28587609 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25891091 — Biomarker: TRIM32 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM32; HT2A
Study 21875859 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17593025 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 12468610 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 12468610 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7639163 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26100336 — Biomarker: AQP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP4
Study 26100336 — Biomarker: AQP9 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP9; SSC1
Study 21729566 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 21729566 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19383225 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 19383225 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9376990 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9376990 — Biomarker: Interleukin 1 alpha
Type: Safety Biomarker (SAF)
Genes: IL1A; IL1F1
Study 9376990 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 9376990 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25886707 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 20521033 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 20521033 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31654573 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 25380901 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19594741 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 11947915 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 10487682 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 1872266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29338073 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 29338073 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 29338073 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 25979762 — Biomarker: miR-34c
Type: Safety Biomarker (SAF)
Genes: MIR34C
Study 22595020 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 22595020 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 22595020 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 1920698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31840813 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 31840813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22835219 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22835219 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10836730 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10836730 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16822279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19151303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16864812 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8456759 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20521985 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20521985 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10764316 — Biomarker: LTB mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB; TNFC; TNFSF3
Study 10764316 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9034259 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8287667 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30178092 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30178092 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 30178092 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28143522 — Biomarker: TCF7L2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCF7L2; TCF4
Study 28143522 — Biomarker: HPGD mRNA
Type: Predictive Biomarker (PRD)
Genes: HPGD; PGDH1; SDR36C1
Study 28143522 — Biomarker: Growth/differentiation factor 15
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 14761117 — Biomarker: FCGR2B
Type: Predictive Biomarker (PRD)
Genes: CD32; CD32B; FcgammaRIIb; FcGRIIB
Study 14761117 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 20178064 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 20178064 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20178064 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8469914 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26954313 — Biomarker: FST mRNA
Type: Predictive Biomarker (PRD)
Genes: FST
Study 12792504 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12792504 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12792504 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 1364978 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31446803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1575821 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 1575821 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 1575821 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30040791 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22355401 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 22355401 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22355401 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 22355401 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9620900 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31665578 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 29186198 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11699169 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30157946 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 20354760 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18552688 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15780531 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 17261503 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study 9666879 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3140622 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 18638603 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 8776678 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3881209 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31101977 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 31101977 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 31101977 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 27082551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22286528 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9673558 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 25487027 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25487027 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 24070809 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24070809 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 24070809 — Biomarker: FZD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FZD4
Study 24070809 — Biomarker: HTRA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HTRA1; HTRA; PRSS11
Study 24070809 — Biomarker: EPAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPAS1; BHLHE73; HIF2A; MOP2; PASD2
Study 24070809 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18728936 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 30250134 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30250134 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17712585 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 319922 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27483410 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 27483410 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 27483410 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17112853 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14988972 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28561039 — Biomarker: LIPA mRNA
Type: Predictive Biomarker (PRD)
Genes: LIPA
Study 11093050 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 11093050 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 29314659 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 29314659 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26854246 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 22880097 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20956902 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10828084 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 10828084 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 10828084 — Biomarker: PLTP mRNA
Type: Predictive Biomarker (PRD)
Genes: PLTP
Study 10828084 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6345370 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25493193 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25493193 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25493193 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25493193 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 22516310 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29126292 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 6378988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26681752 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 26681752 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24375159 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2