AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 30593689 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27220840 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27220840 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15767219 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 31535143 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 31535143 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 25003812 — Biomarker: DKK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DKK1; UNQ492/PRO1008
Study 25003812 — Biomarker: Sclerostin
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: SOST; UNQ2976/PRO7455/PRO7476
Study 2260146 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6779673 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28217871 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28217871 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21212059 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19186961 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 2529108 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 1068646 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 14734517 — Biomarker: ADORA2A
Type: Safety Biomarker (SAF)
Genes: RDC8
Study 28722766 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27457257 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16841676 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 11036121 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11036121 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8858271 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8858271 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20535920 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30627845 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30627845 — Biomarker: BSG mRNA
Type: Predictive Biomarker (PRD)
Genes: BSG; UNQ6505/PRO21383
Study 27811204 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 27811204 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 27811204 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23689036 — Biomarker: SLC5A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A1; NAGT; SGLT1
Study 23689036 — Biomarker: SLC2A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A5; GLUT5
Study 17356110 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 2892458 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27294814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24552320 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24552320 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23750033 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23750033 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30249121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27160246 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27160246 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18158849 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 16316352 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7962441 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 3688927 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27576169 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24786217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24786217 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16192247 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8626943 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31505974 — Biomarker: Hydroxyphenylpyruvate dioxygenase
Type: Safety Biomarker (SAF)
Genes: HPD; PPD
Study 21830844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7657919 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31273244 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 25689743 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 22126115 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 30768490 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 28774856 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 28774856 — Biomarker: ELK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELK3; NET; SAP2
Study 11740191 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9758086 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29603591 — Biomarker: Histone acetylation
Type: Pharmacodynamic Biomarker (PDY)
Study 12823389 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9685441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10026839 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 10026839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29077152 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21613972 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 13678770 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29112963 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24270132 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11579891 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 15253956 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 15253956 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11849859 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11849859 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16728696 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6497518 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 21070297 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21070297 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21070297 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21070297 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14720615 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9114758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8625548 — Biomarker: LGSN mRNA
Type: Predictive Biomarker (PRD)
Genes: LGSN; GLULD1; LGS
Study 1340743 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30178515 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 27553581 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24554512 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24554512 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15321222 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7923256 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3136963 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 26445075 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19293355 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19293355 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 19293355 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26517587 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 11312481 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7717370 — Biomarker: RARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RARS1; RARS
Study 26482865 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 26482865 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 26482865 — Biomarker: TFAM mRNA
Type: Predictive Biomarker (PRD)
Genes: TFAM; TCF6; TCF6L2
Study 26482865 — Biomarker: SOD2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SOD2
Study 26482865 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 22180452 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22180452 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19566585 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 16253583 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16253583 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17264952 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17264952 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17264952 — Biomarker: FGB mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGB
Study 11583477 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26082611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19694343 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30203153 — Biomarker: UST mRNA
Type: Predictive Biomarker (PRD)
Genes: UST; DS2ST
Study 30203153 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 27507876 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19865076 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 7844365 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2216216 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21406101 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3627593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9296893 — Biomarker: OTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 16706755 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 11397885 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20728522 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8683228 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 6348763 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29703800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27621394 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22965962 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22965962 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25646363 — Biomarker: PLB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLB1; PLB
Study 24326980 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 24326980 — Biomarker: TRPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPA1; ANKTM1
Study 19221402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15489844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16123227 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16123227 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31141497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21750253 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21750253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17445589 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16198251 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23455699 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23455699 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19781325 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 3541602 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3541602 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19293592 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19293592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10496437 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17372036 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 17372036 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 17372036 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 11849155 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 11849155 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 27191247 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 27191247 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27191247 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30048547 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 10231223 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 8897027 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8897027 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 6363154 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30369351 — Biomarker: CARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARS1; CARS
Study 23088168 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10378127 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8655705 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 26654738 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26654738 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18174769 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17186724 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 12811626 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 12811626 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1497132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22421463 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21250571 — Biomarker: FST mRNA
Type: Predictive Biomarker (PRD)
Genes: FST
Study 15919688 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15919688 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15919688 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 7758234 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24049109 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 20606594 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8907211 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 23649091 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23649091 — Biomarker: HLA-DQA1
Type: Safety Biomarker (SAF)
Genes: CELIAC1
Study 23649091 — Biomarker: HLA-DQB1
Type: Safety Biomarker (SAF)
Genes: IDDM1; CELIAC1
Study 12837664 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 12837664 — Biomarker: HES1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HES1; BHLHB39; HL; HRY
Study 1712270 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18641036 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1681264 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1681264 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31482947 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25744418 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9139274 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29975331 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 29975331 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22495696 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10206443 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10206443 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 10206443 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28516381 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28516381 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26846591 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26846591 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16644319 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15011419 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27770819 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 15867182 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 27165954 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24220224 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 24220224 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15699836 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 15699836 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15699836 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29778861 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29778861 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 22529197 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 7756795 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 31941389 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 11434356 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9504626 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9504626 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 3288846 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31620079 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21240480 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 18245542 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11152083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9167751 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25256937 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 22733160 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 19951314 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21978796 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21978796 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 24499494 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24499494 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17207668 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS