AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 9615912 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18786258 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 7537355 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 1974664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29333081 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23816015 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9065538 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 27100726 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27100726 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12869088 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29193093 — Biomarker: ACADM mRNA
Type: Predictive Biomarker (PRD)
Genes: ACADM
Study 29193093 — Biomarker: IRS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRS2
Study 29193093 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 23656841 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 17239355 — Biomarker: SLC6A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 8174049 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29540217 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 28746231 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 26439936 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15754270 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12618533 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29908688 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27703294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21029610 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7552519 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26943500 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 12141723 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 12141723 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 12141723 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 12141723 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19538331 — Biomarker: Major prion protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRNP; ALTPRP; PRIP; PRP
Study 9117021 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 3731678 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21862454 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14634543 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6343871 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 16607076 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 19704158 — Biomarker: FST mRNA
Type: Predictive Biomarker (PRD)
Genes: FST
Study 26294364 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22735432 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 22735432 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26471584 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26471584 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19293413 — Biomarker: ACAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAT1; ACAT; MAT
Study 19293413 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3731893 — Biomarker: PLB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLB1; PLB
Study 25880068 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9771209 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9771209 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 798195 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 26263075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14739050 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10669363 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9107443 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9107443 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1315560 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30957391 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26740254 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26740254 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26740254 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26740254 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26740254 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26740254 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 26740254 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28199805 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21512825 — Biomarker: Gamma-Histone H2AX
Type: Pharmacodynamic Biomarker (PDY)
Genes: H2AX; H2AFX
Study 14701900 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9116271 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 30215735 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30053896 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30053896 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 10683057 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 15691793 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 29944706 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 26861865 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9025819 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27489241 — Biomarker: KLRK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRK1; D12S2489E; NKG2D
Study 27489241 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21644308 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10232502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26743587 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26743587 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18614930 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23768003 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 17284748 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 17284748 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 28747642 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 28747642 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18642209 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 18642209 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 18642209 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16564940 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 16564940 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24370543 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9796842 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7713815 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 23918588 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 23918588 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 22192511 — Biomarker: KIF6 mRNA
Type: Predictive Biomarker (PRD)
Genes: KIF6; C6orf102
Study 22192511 — Biomarker: TAS2R50 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAS2R50
Study 22192511 — Biomarker: VAMP8 mRNA
Type: Predictive Biomarker (PRD)
Genes: VAMP8
Study 22192511 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10172365 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 30421455 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28329092 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 28329092 — Biomarker: FUT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FUT2; SEC2
Study 22294255 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22294255 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22294255 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 22294255 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22294255 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 19963031 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19963031 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 17496286 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7789048 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2189149 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7322959 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27428710 — Biomarker: S100A8 mRNA
Type: Predictive Biomarker (PRD)
Genes: S100A8; CAGA; CFAG; MRP8
Study 27428710 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 24048773 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12677302 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1334283 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28987358 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17102570 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2824710 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 25908323 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 11094866 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3830478 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 27417562 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27417562 — Biomarker: SERPINF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINF1; PEDF; PIG35
Study 27417562 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 19026036 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 19026036 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 11716647 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 2258877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7368972 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27118495 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30808022 — Biomarker: GDNF mRNA
Type: Predictive Biomarker (PRD)
Genes: GDNF
Study 25410068 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 18319308 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 15944847 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 12866746 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 12499333 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10818325 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10818325 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19404210 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study 16894934 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16894934 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 11453879 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 11453879 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 1416135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22809630 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17585664 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 2258876 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2258876 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9590463 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9590463 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 29263150 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18798327 — Biomarker: MPG mRNA
Type: Predictive Biomarker (PRD)
Genes: MPG; AAG; ANPG; MID1
Study 18798327 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 16176058 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 1867232 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1867232 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3196530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3196530 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 28381266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18283176 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 16626574 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 16626574 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19576927 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14715853 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28726169 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19339887 — Biomarker: XRCC1
Type: Safety Biomarker (SAF)
Genes: RCC
Study 11329233 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3122113 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 29497290 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 29497290 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12508388 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 10533691 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 7009424 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24037492 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17355215 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15825717 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8944409 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 1742482 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 1742482 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1742482 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12010339 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8580277 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30967395 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29747616 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study 29747616 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 29747616 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19292590 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3360270 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 31599692 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 31599692 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study 31599692 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 31599692 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31599692 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29132458 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26331821 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 12840625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12840625 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 10488604 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2052631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6315775 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 6315775 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 9509971 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9509971 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 7800170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2784382 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 27073832 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15998278 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 12706919 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 12706919 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 11741217 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6365463 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27117850 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 12173810 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3328986 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29795665 — Biomarker: APRT mRNA
Type: Predictive Biomarker (PRD)
Genes: APRT
Study 19439966 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 19439966 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 19439966 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19439966 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 19439966 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15057894 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 11694151 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2827044 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2827044 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11257242 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 19647945 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 14694237 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 28225052 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21205384 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21205384 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16613341 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14600814 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14600814 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9313596 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1