AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 15696567 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1991653 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1991653 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6140837 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 31296293 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 17638395 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17454966 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29617391 — Biomarker: ACAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAT1; ACAT; MAT
Study 24274358 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 24274358 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10907666 — Biomarker: DRD3
Type: Safety Biomarker (SAF)
Study 6545038 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24721435 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21700548 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15451058 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10770539 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17440998 — Biomarker: F7 mRNA
Type: Predictive Biomarker (PRD)
Genes: F7
Study 7584882 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2318372 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6965324 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30640655 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28494915 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8793675 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30113651 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 30113651 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 30113651 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 25332247 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25332247 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 25332247 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 25332247 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 25332247 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 25332247 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22190020 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12826169 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10760045 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 29730798 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10071177 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 30723886 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18413006 — Biomarker: Alpha-glutathione S-transferase
Type: Safety Biomarker (SAF)
Study 18413006 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 15975964 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12874091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8026109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8026109 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 8026109 — Biomarker: Urinary total protein
Type: Safety Biomarker (SAF)
Study 790128 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17726250 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15102080 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study 9351881 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9817169 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 9817169 — Biomarker: Cyclin-dependent kinase inhibitor 1
Type: Safety Biomarker (SAF)
Genes: CDKN1A
Study 17289910 — Biomarker: SLC16A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC16A4; MCT4; MCT5
Study 17289910 — Biomarker: SLC9A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC9A1; APNH1; NHE1
Study 17289910 — Biomarker: MCTS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCTS1; MCT1
Study 15326091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31098654 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31098654 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 22947179 — Biomarker: HTR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2A; HTR2
Study 22947179 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 22947179 — Biomarker: NR3C1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR3C1; GRL
Study 22947179 — Biomarker: MAOA mRNA
Type: Predictive Biomarker (PRD)
Genes: MAOA
Study 16148616 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8829823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8829823 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17295293 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8466740 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29493875 — Biomarker: PEF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PEF1; ABP32; UNQ1845/PRO3573
Study 19788592 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 19788592 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 19788592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15671131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12730285 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 3993154 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29995952 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 20937127 — Biomarker: FMR1
Type: Predictive Biomarker (PRD)
Genes: FMRP; FRAXA; MGC87458
Study 10337860 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 7299611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31422879 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 30167830 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26260705 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26260705 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26019878 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26019878 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24794447 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 24794447 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24794447 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24794447 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20921983 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 18925530 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 18925530 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 15741753 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12393614 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7860762 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 1789379 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 30079432 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 12269969 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 12269969 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24333089 — Biomarker: RHD mRNA
Type: Predictive Biomarker (PRD)
Genes: RHD
Study 24333089 — Biomarker: RHCE mRNA
Type: Predictive Biomarker (PRD)
Genes: RHCE; RHC; RHE
Study 8905024 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8905024 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 6124268 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16950469 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15052623 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24360368 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 14645968 — Biomarker: CAMP mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMP; CAP18; FALL39; HSD26
Study 14645968 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24289108 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 24289108 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 22781199 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17317135 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17317135 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 14748763 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 11606503 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 7993155 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7993155 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7993155 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2191764 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 34186 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 30135176 — Biomarker: CXADR mRNA
Type: Predictive Biomarker (PRD)
Genes: CXADR; CAR
Study 10966281 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 6407429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24816453 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 15699284 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15699284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11905407 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11905407 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 11905407 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21377073 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 17414703 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11528581 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3371082 — Biomarker: OTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 29661746 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26952547 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22573363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20379853 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18355411 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 18355411 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18355411 — Biomarker: STC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STC1; STC
Study 18355411 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 18355411 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26112656 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 22930151 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22930151 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16461190 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25017001 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20018807 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16556720 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 12903044 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 26345103 — Biomarker: TKT mRNA
Type: Predictive Biomarker (PRD)
Genes: TKT
Study 26345103 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 16339664 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 1642186 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1642186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12103382 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10408031 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 3555578 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26242380 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 25399229 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25399229 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 12593019 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 1744909 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31703120 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31703120 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 9844044 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 19491420 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 2426899 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 28939330 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27225520 — Biomarker: TTN mRNA
Type: Predictive Biomarker (PRD)
Genes: TTN
Study 25074507 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25074507 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12001058 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10469288 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2213631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23649684 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 11412828 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 11412828 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 11412828 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 22905105 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22905105 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 29947648 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8923869 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29590534 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27237200 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 22382344 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17462549 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14718433 — Biomarker: Nasal potential difference
Type: Pharmacodynamic Biomarker (PDY)
Study 14718433 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 1433666 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 6376951 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25048075 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25048075 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22964355 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12640369 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 1501354 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30573707 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 29111980 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25877422 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 20635451 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 367865 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28145158 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 28145158 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 10952418 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 9222947 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26938953 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26938953 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22278145 — Biomarker: GRK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRK4; GPRK2L; GPRK4
Study 20578209 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 20578209 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16208701 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 25216508 — Biomarker: PDPN mRNA
Type: Predictive Biomarker (PRD)
Genes: PDPN; GP36; PSEC0003; PSEC0025
Study 12385861 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 12385861 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12385861 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 31813423 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 29806413 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1959859 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27572830 — Biomarker: PDE10A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE10A
Study 19132338 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 19132338 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17602979 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10678408 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10678408 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16525751 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16525751 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9684746 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26342026 — Biomarker: AGTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study 26342026 — Biomarker: FOXI2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXI2
Study 26342026 — Biomarker: PENK mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PENK
Study 29678360 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 26892135 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26892135 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26892135 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22135493 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9256323 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 3543093 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3543093 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)