AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 20940336 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 8030656 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18653268 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30709958 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28682289 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 11528252 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 11528252 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 7836521 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 19422759 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 15385013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11527684 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 27464544 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27464544 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 20393026 — Biomarker: TAOK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 15991060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31595861 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 25835116 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25835116 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25835116 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 25835116 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 31608503 — Biomarker: LAMB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMB2; LAMS
Study 28710229 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26338453 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15851238 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11437040 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 7526007 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 1157005 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 23953528 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21741088 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21741088 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28644774 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 17063425 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 6412795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21252018 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 18214425 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 8869676 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30217233 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25196301 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12011970 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10466952 — Biomarker: PIMREG mRNA
Type: Predictive Biomarker (PRD)
Genes: PIMREG; CATS; FAM64A; RCS1
Study 31787562 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 27918780 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15006828 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9033316 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24132138 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6092555 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 29920211 — Biomarker: ABCG5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG5
Study 29920211 — Biomarker: DHCR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: DHCR7; D7SR
Study 29920211 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24401211 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24401211 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11811169 — Biomarker: C1QL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 21932114 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21932114 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19188545 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18265541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18265541 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18265541 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9164824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31200662 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 31200662 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25880814 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 19001742 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 30019357 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 11527172 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 11527172 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 7920930 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 29407633 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 29407633 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18842969 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18842969 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2787887 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 23760911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18714500 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 27062408 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29684092 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25578377 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 28829670 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27225761 — Biomarker: NE
Type: Predictive Biomarker (PRD)
Study 23864720 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 11211168 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9772136 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 9772136 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30281924 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 30281924 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 30281924 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 30281924 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 30281924 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 30281924 — Biomarker: OPRM1
Type: Safety Biomarker (SAF)
Genes: MOR1; MOP
Study 16452736 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15212653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15212653 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15212653 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 15212653 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 11301961 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19745828 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15891523 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15891523 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 15891523 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 15891523 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11641293 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30051179 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 30051179 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 30051179 — Biomarker: Activated leukocyte cell adhesionmolecule
Type: Predictive Biomarker (PRD)
Genes: ALCAM; MEMD
Study 30051179 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28676236 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26041510 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 24612221 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 24612221 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17903157 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 31351062 — Biomarker: WAP four-disulfide core domain protein 2
Type: Predictive Biomarker (PRD)
Genes: WFDC2; HE4; WAP5
Study 31351062 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 30178600 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 22110589 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9020538 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20738062 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 1830108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19891698 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 8549849 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30859660 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25120022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12837854 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study 3890140 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 24952868 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18315507 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15966876 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 7715474 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21255780 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21255780 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8365423 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26669642 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26669642 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 23265585 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 17277734 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 7666085 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 6804113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17674759 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 31185917 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25046055 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 10024837 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10024837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2240002 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16728216 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 27921320 — Biomarker: MBTPS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBTPS1; KIAA0091; S1P; SKI1
Study 25195813 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 23449607 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15853118 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10640980 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 12601105 — Biomarker: GAPDH mRNA
Type: Predictive Biomarker (PRD)
Genes: GAPDH; GAPD; CDABP0047; OK/SW-cl.12
Study 1854617 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 6147940 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24915941 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 10382127 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 1919540 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 1919540 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 27196998 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 10980877 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27511452 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 15334379 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29785872 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29785872 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29785872 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23175912 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10344454 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31024092 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30830076 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 25711726 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 25711726 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25711726 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16442902 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31526206 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 27353076 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 16794641 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8043291 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 31811010 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 8144779 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 8144779 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 10624454 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10624454 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2172501 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21244240 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19591795 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19591795 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9551706 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 8141156 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8141156 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8141156 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17055858 — Biomarker: FMOD mRNA
Type: Predictive Biomarker (PRD)
Genes: FMOD; FM; SLRR2E
Study 12743557 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 10560780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15599837 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27618091 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 1921737 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 1921737 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11701672 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 11701672 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 26380438 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21934637 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 15545150 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26176592 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8603262 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8603262 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8603262 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 7044649 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7044649 — Biomarker: ABCD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCD1; ALD
Study 7044649 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30452533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23913868 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19150064 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7869212 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 2531718 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 28472383 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22821223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26613955 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 26613955 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 26613955 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 16914369 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12173784 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 2496993 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18637604 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16767526 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3528969 — Biomarker: FANCC
Type: Predictive Biomarker (PRD)
Genes: FAC; FA3
Study 12482765 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 12482765 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11318005 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 29980595 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29980595 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24947045 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22104390 — Biomarker: MAVS mRNA
Type: Predictive Biomarker (PRD)
Genes: MAVS; IPS1; KIAA1271; VISA
Study 12445035 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 12445035 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 7547823 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2201403 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 6996139 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25294299 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29354933 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 10833331 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 8441234 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 31066232 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 7834398 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6155131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18447631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9467249 — Biomarker: HBA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HBA1; HBA2
Study 6702613 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6702613 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30557325 — Biomarker: PTGDR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 21076721 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 21076721 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21076721 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1