AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 15240537 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 15240537 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2427301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10071299 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 10071299 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 23807094 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21155632 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30593463 — Biomarker: Survival motor neuron protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 26401255 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26401255 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26401255 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23467813 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 23467813 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20970351 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9564119 — Biomarker: TRO mRNA
Type: Predictive Biomarker (PRD)
Genes: TRO; KIAA1114; MAGED3
Study 2721537 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11339099 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9549925 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9928754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2125646 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2125646 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 7471064 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20404379 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20404379 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6463391 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29716940 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 29716940 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29716940 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20075335 — Biomarker: ABCG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG1; ABC8; WHT1
Study 17765133 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15673327 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29145211 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17400086 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 22161728 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22161728 — Biomarker: New morphometric vertebral fractures
Type: Surrogate Endpoint (SUR)
Study 22161728 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19786251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15911864 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 3388475 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 350251 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 15713727 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 31336497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25459687 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 25459687 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25617561 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25617561 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22137672 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 22137672 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 22137672 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28658164 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12864878 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12864878 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8165074 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18272959 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1851785 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1851785 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1851785 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 1851785 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 7226124 — Biomarker: MERTK mRNA
Type: Predictive Biomarker (PRD)
Genes: MERTK; MER
Study 30646884 — Biomarker: MCCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCCC2; MCCB
Study 22240754 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26481226 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 24574085 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 20425759 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20425759 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 20425759 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 7614898 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28668386 — Biomarker: MXD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MXD1; MAD
Study 16352815 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 15285851 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 20605872 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7595101 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 7595101 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1850942 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17006667 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 17006667 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 15567189 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 15567189 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 24920046 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6504708 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 29511971 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20642481 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 31307527 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 31307527 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 31307527 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 31307527 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31307527 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22013952 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 18818699 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 15228864 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9832299 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 2553425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19580019 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14994690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11320899 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9129083 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 30838389 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16318774 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8592593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31483963 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17595888 — Biomarker: RNF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RNF2; BAP1; DING; HIPI3; RING1B
Study 10678541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10678541 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9164806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30103509 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 7600120 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 7600120 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 9480238 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9480238 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 7894531 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 7894531 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30639252 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30639252 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22113536 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 22113536 — Biomarker: UCP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP3; SLC25A9
Study 17092241 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 17092241 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 15243302 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 11341175 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 8861797 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24053577 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24053577 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11755289 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30666100 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 19405831 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 4082084 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 29846607 — Biomarker: BMAL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BMAL1; ARNTL; BHLHE5; MOP3; PASD3
Study 29846607 — Biomarker: AANAT mRNA
Type: Predictive Biomarker (PRD)
Genes: AANAT; SNAT
Study 29846607 — Biomarker: CREB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CREB3; LZIP
Study 29846607 — Biomarker: PRKAR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKAR2A; PKR2; PRKAR2
Study 29846607 — Biomarker: PRKCB mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKCB; PKCB; PRKCB1
Study 29846607 — Biomarker: PER3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PER3; GIG13
Study 29846607 — Biomarker: CAMK2D mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMK2D; CAMKD
Study 29846607 — Biomarker: MAPK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK1; ERK2; PRKM1; PRKM2
Study 28199748 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 12663573 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10704275 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2423343 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25896352 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23720785 — Biomarker: DMBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DMBX1; MBX; OTX3; PAXB
Study 1614045 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31757218 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 20336348 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 19246849 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19246849 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 19246849 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19246849 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19246849 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 16725141 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2658529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9217191 — Biomarker: THPO mRNA
Type: Predictive Biomarker (PRD)
Genes: THPO; MGDF
Study 8483855 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8483855 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3038418 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3038418 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26742700 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20588105 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16809807 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2905711 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 29398050 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29398050 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26139745 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26139745 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26139745 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31640757 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 23832498 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 21464401 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9014018 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 3901391 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 11915093 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23651846 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 23651846 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 17160982 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11367649 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31995838 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 24674297 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21987195 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 21987195 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9144352 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 2826549 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25913166 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20626664 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12648882 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12648882 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 10951830 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31745072 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31745072 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31745072 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 8847044 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8847044 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30175557 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 2678309 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16864756 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11719736 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 7787215 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 7787215 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 16981473 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 9215828 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30414797 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 10205312 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 3217222 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 23745526 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31483964 — Biomarker: PKLR mRNA
Type: Predictive Biomarker (PRD)
Genes: PKLR; PK1; PKL
Study 27304428 — Biomarker: MMP12 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP12; HME
Study 27304428 — Biomarker: PI3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PI3; WAP3; WFDC14
Study 27304428 — Biomarker: CXCL1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 27304428 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC
Study 21734059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15609886 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15609886 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29950456 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27721228 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24781374 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 22732470 — Biomarker: SFPQ mRNA
Type: Predictive Biomarker (PRD)
Genes: SFPQ; PSF
Study 1742480 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 11531012 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 8029811 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 27333913 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 27333913 — Biomarker: STAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT1
Study 27333913 — Biomarker: HSPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPB1; HSP27; HSP28
Study 8244516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15013305 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 7944706 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 25387655 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11156125 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 29587288 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 29587288 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20413121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12010586 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 12010586 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27349705 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26944583 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 26944583 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21996058 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 6089307 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6089307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30889043 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 23269112 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15016251 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11150970 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 7910838 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16478626 — Biomarker: TYMS
Type: Predictive Biomarker (PRD)
Genes: Tsase; TMS; HsT422
Study 12575604 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3684126 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP