AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 21961780 — Biomarker: STAR mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAR; STARD1
Study 16611342 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 29105987 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 25118263 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 9250553 — Biomarker: MPG mRNA
Type: Predictive Biomarker (PRD)
Genes: MPG; AAG; ANPG; MID1
Study 30319663 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30319663 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30319663 — Biomarker: CXCL1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 30319663 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 23148885 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11072156 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11072156 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 11072156 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 11072156 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 11072156 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11072156 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8821843 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18251212 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18251212 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16825335 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10678254 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10678254 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9010691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6377891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26611571 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26611571 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16472588 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9604449 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 2422467 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31575503 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study 30521366 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 25941160 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 23465039 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7889665 — Biomarker: PCLAF mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 23980523 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23320821 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 23320821 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17714576 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16160710 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12838495 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21623778 — Biomarker: ADIPOQ mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 11514376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18297434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14576756 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10526245 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 6341015 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 23529273 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 23529273 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 16287602 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2695549 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12767415 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11323338 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10376122 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 19148479 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 15614997 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 31393548 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22721642 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22721642 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17136007 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17136007 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10751266 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 9223837 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9223837 — Biomarker: VASH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VASH1; KIAA1036; VASH
Study 30526573 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19477145 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 16912120 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 16912120 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 11144049 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 29059273 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 20859637 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 20859637 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 16996868 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19890266 — Biomarker: Fatty acid amide hydrolase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: FAAH; FAAH1
Study 7563935 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23042313 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18565887 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 18565887 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 10051263 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 10051263 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 7674104 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20797477 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9295485 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11584093 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 2540005 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30004111 — Biomarker: DEFA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: DEFA5; DEF5
Study 30004111 — Biomarker: REG3A mRNA
Type: Predictive Biomarker (PRD)
Genes: REG3A; HIP; PAP; PAP1
Study 12369794 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 12369794 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19451915 — Biomarker: GRM3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRM3; GPRC1C; MGLUR3
Study 19451915 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 3115843 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 18166408 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 30415553 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30415553 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23132511 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 17328999 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 15809948 — Biomarker: EDA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDA; ED1; EDA2
Study 11498318 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8989009 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25311651 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 21306828 — Biomarker: MMD mRNA
Type: Predictive Biomarker (PRD)
Genes: MMD; PAQR11
Study 28977167 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26607778 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 25316464 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 25415805 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 12821755 — Biomarker: Amyloid beta peptide (1-40)
Type: Pharmacodynamic Biomarker (PDY)
Genes: APP; A4; AD1
Study 1379106 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26729211 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 18426821 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18426821 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 18426821 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 18426821 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 18426821 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16635750 — Biomarker: MBTPS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBTPS1; KIAA0091; S1P; SKI1
Study 16635750 — Biomarker: CCR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 16635750 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 3915460 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23141790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9720517 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 29474863 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25922848 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18619686 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 17362251 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12577374 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 12577374 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12577374 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9502344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8017642 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 15330272 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21726496 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 19417675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3403863 — Biomarker: PCLAF mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 21288233 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 30833349 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30833349 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 30833349 — Biomarker: miR-223
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR223
Study 11719727 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 9222234 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9063814 — Biomarker: ALDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH2; ALDM
Study 3294978 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16100213 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11501126 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29475784 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16997421 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9658727 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9658727 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 23413266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21540753 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21540753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14533211 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8973986 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12061197 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7428566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25211663 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 10321786 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31073102 — Biomarker: RYR1
Type: Safety Biomarker (SAF)
Genes: RYR; PPP1R137
Study 15169848 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15169848 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 15169848 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7981579 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29428199 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 8538349 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1651738 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 29694963 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 24483158 — Biomarker: ADORA2A
Type: Safety Biomarker (SAF)
Genes: RDC8
Study 23030673 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25346345 — Biomarker: PRTG mRNA
Type: Predictive Biomarker (PRD)
Genes: PRTG
Study 8420303 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8420303 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8420303 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30074128 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 24808022 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 24808022 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 22825506 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16160068 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 12694895 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 12694895 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11057425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31570825 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 26896828 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26896828 — Biomarker: TNF-related weak inducer of apoptosis
Type: Predictive Biomarker (PRD)
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study 20808814 — Biomarker: Hydroxyphenylpyruvate dioxygenase
Type: Safety Biomarker (SAF)
Genes: HPD; PPD
Study 18845807 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22941872 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31760314 — Biomarker: ASNS mRNA
Type: Predictive Biomarker (PRD)
Genes: ASNS; TS11
Study 28720242 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2889678 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17064611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17064611 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10855346 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 7677827 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 7677827 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 7677827 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 31272709 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31272709 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11246842 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 7525240 — Biomarker: SLC10A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC10A3; DXS253E; P3
Study 18209510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25611116 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 19824413 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29566128 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 29566128 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28303624 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28303624 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 24035299 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21406489 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12768300 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 9091852 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 29223956 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17890876 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 10958127 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20556559 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 15314950 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 25694350 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17507322 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12401595 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26909792 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26909792 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30127049 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 27034623 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18830857 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 14659770 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14659770 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 14659770 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 14659770 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 14659770 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 8412148 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 8412148 — Biomarker: ROPN1L mRNA
Type: Predictive Biomarker (PRD)
Genes: ROPN1L; ASP; RSPH11
Study 25330837 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 12853784 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 6087129 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 30713022 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 18060091 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18060091 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31252598 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 16061839 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 30778004 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24518152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23329572 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 14761123 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 27356528 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27356528 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 27356528 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 15735389 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)