AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 27936169 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 19225400 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11279411 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8989263 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 20497745 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 20497745 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 10835452 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 3736281 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24088749 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24088749 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 19624691 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15266766 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11497198 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11497198 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9513582 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18266878 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18266878 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8469319 — Biomarker: UBC mRNA
Type: Predictive Biomarker (PRD)
Genes: UBC
Study 9588606 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 30646129 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 10372711 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2051004 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 29582053 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 24913837 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 16264047 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 21917518 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21917518 — Biomarker: TOP2A mRNA
Type: Predictive Biomarker (PRD)
Genes: TOP2A; TOP2
Study 18937013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16913498 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 14709940 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 11137416 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8265878 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 3011023 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3011023 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30537261 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21455612 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21455612 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23913601 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 8713772 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1439288 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2986932 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30371169 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30371169 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27423256 — Biomarker: PDE10A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE10A
Study 25483462 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 19629583 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22174039 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18416221 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 18416221 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15884752 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 12074773 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 1937659 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15293079 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15293079 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 25935422 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22149470 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11126465 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21224436 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16508584 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18550933 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15820793 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8881840 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8881840 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8510082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2961938 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 31637452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23628696 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 19793768 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 19793768 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19793768 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16670135 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10381288 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 10381288 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 29749323 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8551733 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 8551733 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 389419 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 389419 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 389419 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 389419 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31434498 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24969577 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 22099425 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30004255 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10334388 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31502323 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26455521 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22143452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19317824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11163559 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 28486329 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 28486329 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19695194 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 11566623 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11566623 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11566623 — Biomarker: Proliferation marker protein Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67
Study 9785067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30672234 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30672234 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30672234 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30672234 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 30672234 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 24085784 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 24085784 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 24085784 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 24085784 — Biomarker: CD24 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD24; CD24A
Study 24085784 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18242338 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 16845251 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16845251 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1626037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30182359 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 30182359 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 20080842 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8140926 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 386062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25296344 — Biomarker: FOXO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXO1; FKHR; FOXO1A
Study 24912899 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9521232 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2533973 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2533973 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23589562 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23589562 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15181130 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8841148 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19368768 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 16448520 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16448520 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16448520 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12633795 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10835443 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 20664534 — Biomarker: SLCO2B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 20664534 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 26021958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17619851 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 30351388 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30351388 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10381291 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8963837 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 8963837 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18492754 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8729614 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 27017207 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 24375969 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17341532 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3098484 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30518682 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 22745245 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 22745245 — Biomarker: c-Jun N-terminal kinase
Type: Safety Biomarker (SAF)
Study 22745245 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22745245 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8644689 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3552458 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7515649 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 7515649 — Biomarker: RTEL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RTEL1; C20orf41; KIAA1088; NHL
Study 2454376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25131773 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25131773 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25131773 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 25131773 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22572633 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 22572633 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25763201 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20678674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8258959 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8258959 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8258959 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 4042390 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25225285 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25225285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15014210 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 8077888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2589002 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29162132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31899035 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31899035 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 31899035 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 31899035 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22000810 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 22000810 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31099387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9737514 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 25262178 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 25262178 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 25262178 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 18069576 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 366141 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25052361 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22399699 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16316360 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16316360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10826395 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10826395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8651166 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29762253 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31505228 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 28091858 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21471414 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19123930 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 17317762 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 15750983 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8187255 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25650049 — Biomarker: HTR2C mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2C; HTR1C
Study 19208649 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 19208649 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 10853626 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9104515 — Biomarker: EDA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDA; ED1; EDA2
Study 9104515 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3572208 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21778247 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19433800 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 11371683 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28041817 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 28041817 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24244325 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20833235 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20833235 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 18496373 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 25503770 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9928753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7495045 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23218813 — Biomarker: SPN mRNA
Type: Predictive Biomarker (PRD)
Genes: SPN; CD43
Study 30400570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30400570 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30400570 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30400570 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20858857 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10355866 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 29782224 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 29782224 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 24581894 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 9603592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26661992 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 22791756 — Biomarker: NES mRNA
Type: Predictive Biomarker (PRD)
Genes: NES; Nbla00170
Study 18195264 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 25802954 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23339811 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 9424900 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 14610160 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1