AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 14872246 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 14872246 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 14872246 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8305412 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 8305412 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26370445 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3733491 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 8230572 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26447668 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 21041914 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16808310 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 16808310 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 3389898 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 354829 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 354829 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26360837 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 26360837 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 26360837 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 21339244 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 30578013 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24220555 — Biomarker: Solute carrier family 29 member 1
Type: Predictive Biomarker (PRD)
Genes: SLC29A1; ENT1
Study 7868799 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 7868799 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 7868799 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 21296694 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 15254792 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 8257887 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25457929 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 20605499 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20605499 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20605499 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8950072 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8950072 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 28732480 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 28732480 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 2340210 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31915163 — Biomarker: CSAD mRNA
Type: Predictive Biomarker (PRD)
Genes: CSAD; CSD
Study 19291119 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 17522570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11788176 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 9711425 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 9711425 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2731120 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 19776222 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 19776222 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30120069 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 26980389 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 10817585 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 22251483 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 22251483 — Biomarker: KLRK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRK1; D12S2489E; NKG2D
Study 16332666 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 17914032 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9274891 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23715754 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 10526701 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7795096 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22934858 — Biomarker: XCL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: XCL1; LTN; SCYC1
Study 19900154 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 10636271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29322610 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 24697877 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 24697877 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 24697877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12795771 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25450583 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 12592333 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 1860749 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 24837306 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8758833 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8758833 — Biomarker: STIL mRNA
Type: Predictive Biomarker (PRD)
Genes: STIL; SIL
Study 2523770 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 16416230 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25893930 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 25893930 — Biomarker: miR-125b
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25893930 — Biomarker: miR-92a-3p
Type: Monitoring Biomarker (MOI)
Study 9125276 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 25549192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22179601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17364234 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 8560901 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3389862 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 31407230 — Biomarker: FAT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FAT3; CDHF15; KIAA1989
Study 31407230 — Biomarker: PKHD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PKHD1; FCYT; TIGM1
Study 31407230 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 31407230 — Biomarker: GATA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GATA3
Study 31407230 — Biomarker: PARP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PARP4; ADPRTL1; KIAA0177; PARPL
Study 31407230 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 21381497 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 27384040 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 17379017 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17379017 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 3056085 — Biomarker: Argininosuccinate synthase
Type: Safety Biomarker (SAF)
Genes: ASS1; ASS
Study 3056085 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 28619175 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 25877694 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18710330 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8903382 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 27083135 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25096822 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 12460330 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 12460330 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2174320 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 30709694 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 20517667 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20517667 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22104363 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15918104 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15918104 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8769362 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22297666 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22297666 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10811588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10969367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3534592 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29198406 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8717532 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23552126 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19555390 — Biomarker: CLDN4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLDN4; CPER; CPETR1; WBSCR8
Study 19555390 — Biomarker: CLDN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLDN3; C7orf1; CPETR2
Study 11474160 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8574271 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 8574271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2159509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31272550 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 31272550 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 14607455 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 14607455 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 14607455 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20728210 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20129212 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10567956 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 1751794 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21380536 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19056656 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 17888974 — Biomarker: CSAD mRNA
Type: Predictive Biomarker (PRD)
Genes: CSAD; CSD
Study 28800765 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18093792 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18093792 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18093792 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 6361299 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29258367 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 29258367 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26606967 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9356538 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 25266547 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 20067654 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20067654 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 1906893 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 21971406 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 11575229 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26966279 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 26966279 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25955191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23509106 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 22321227 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22321227 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22321227 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 19382480 — Biomarker: TBP mRNA
Type: Predictive Biomarker (PRD)
Genes: TBP; GTF2D1; TF2D; TFIID
Study 27160157 — Biomarker: SEPTIN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEPTIN3; SEP3; SEPT3
Study 25403606 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19280097 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19280097 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19280097 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26497961 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18506924 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18506924 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17323614 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17077322 — Biomarker: SERPINB9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINB9; PI9
Study 17077322 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 30005743 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30005743 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26759468 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 23594858 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 23594858 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 20873905 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 9190980 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 27154357 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 27154357 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 20232413 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 2073669 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27627193 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17417917 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 15244246 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 15244246 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2869001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30324553 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 29263660 — Biomarker: CLN8 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLN8; C8orf61
Study 29263660 — Biomarker: PCSK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK5; PC5; PC6
Study 29263660 — Biomarker: SKP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SKP2; FBXL1
Study 29263660 — Biomarker: SPTBN5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPTBN5; BSPECV; HUBSPECV; HUSPECV
Study 29263660 — Biomarker: C1orf115 mRNA
Type: Predictive Biomarker (PRD)
Genes: C1orf115; RDD1
Study 29263660 — Biomarker: RNF213 mRNA
Type: Predictive Biomarker (PRD)
Genes: RNF213; ALO17; C17orf27; KIAA1554; KIAA1618; MYSTR
Study 29263660 — Biomarker: PRKX mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKX; PKX1
Study 29263660 — Biomarker: RHOQ mRNA
Type: Predictive Biomarker (PRD)
Genes: RHOQ; ARHQ; RASL7A; TC10
Study 29263660 — Biomarker: FBN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBN3; KIAA1776
Study 26388284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21719695 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 20178254 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 7493423 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1674394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15247338 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29575406 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20826878 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 16872795 — Biomarker: CSF1R mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF1R; FMS
Study 10933350 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10933350 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 4042547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30007343 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 30007343 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22898365 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 18602144 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 30917287 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 28791808 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 23569894 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12629102 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31853709 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 31820361 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31820361 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31820361 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 28562541 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11588440 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 25231953 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25231953 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25231953 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 21164551 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21164551 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21164551 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10208997 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 2183599 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2183599 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31142441 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28196207 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 28196207 — Biomarker: PDGFRA mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 28196207 — Biomarker: Succinate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: SDHD
Study 19388569 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31444897 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 8776643 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 6749207 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24573180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20102936 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15892275 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10404806 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2202385 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22456951 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 11113837 — Biomarker: LAX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAX1; LAX
Study 3524724 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 24755192 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL