AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 2043220 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31862195 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 19088168 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 19088168 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1419813 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31188268 — Biomarker: HCN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: HCN2; BCNG2
Study 26501464 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 26501464 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26501464 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26501464 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20200239 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 15696331 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 10205352 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28452904 — Biomarker: LGALSL mRNA
Type: Predictive Biomarker (PRD)
Genes: LGALSL; GRP; HSPC159
Study 10574419 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24926075 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24926075 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12689686 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12442030 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 1954661 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 28532408 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25398399 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21219551 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7970505 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29096949 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29096949 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11019429 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1584317 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 23620494 — Biomarker: HSPA1B mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA1B; HSP72
Study 20607877 — Biomarker: EDA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDA; ED1; EDA2
Study 15558237 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8664173 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 8023964 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29241306 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29241306 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29241306 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 29241306 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 23246389 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23246389 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12767083 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8668877 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 1510170 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 29087231 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22123358 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 22123358 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22123358 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22123358 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31042402 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31042402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25881226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23703604 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15459593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15459593 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11263782 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 11263782 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 26811178 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 26811178 — Biomarker: Ribonucleoside-diphosphate reductase large subunit
Type: Predictive Biomarker (PRD)
Genes: RRM1; RR1
Study 18245547 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 18245547 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22170010 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27725233 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 9557932 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9557932 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3071461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22092997 — Biomarker: FECH mRNA
Type: Predictive Biomarker (PRD)
Genes: FECH
Study 22092997 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21164127 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17163254 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17163254 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10719808 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10719808 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 30852486 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22480387 — Biomarker: SLC6A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 22480387 — Biomarker: MC3R mRNA
Type: Predictive Biomarker (PRD)
Genes: MC3R
Study 22480387 — Biomarker: TPH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH2; NTPH
Study 3653970 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27472280 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 24325105 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18405789 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 10714531 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 4037034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28029312 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26678637 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26678637 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24524601 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24524601 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 24524601 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24524601 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21037270 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 22878351 — Biomarker: CALM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CALM2; CAM2; CAMB
Study 23238645 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 1287139 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 20484899 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 20484899 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 20484899 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9725543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30222768 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18310480 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15671109 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 12621386 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 12621386 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 1651211 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24500418 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study 20451215 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 10223776 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 26694436 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24263023 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24263023 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 24263023 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16397290 — Biomarker: CYP2E1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2E1; CYP2E
Study 10452011 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 3827157 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9315595 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18950853 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10915096 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24245566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3071617 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 21899916 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 17448723 — Biomarker: LAX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAX1; LAX
Study 17448723 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 20027554 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25400162 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22006095 — Biomarker: HTR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2A; HTR2
Study 21586712 — Biomarker: LARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LARS1; KIAA1352; LARS
Study 16551904 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 8523374 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31080037 — Biomarker: APOA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOA1
Study 10661337 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 25257975 — Biomarker: SLC2A9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A9; GLUT9
Study 10515648 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8622117 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21947558 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 19375008 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 11544467 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11544467 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 16989023 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16989023 — Biomarker: VEGF
Type: Predictive Biomarker (PRD)
Genes: VEGFA; VEGF-A; VPF
Study 16989023 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12925219 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 3550035 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 24721668 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8531308 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 8531308 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30145342 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 19154828 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 10206300 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 2624987 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 25284616 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7717598 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19274793 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 11907944 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 31880055 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study 29042091 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 19631970 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 19631970 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 19631970 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 19631970 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7947424 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30074402 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 18480202 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10821298 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 10821298 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10821298 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 6573807 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 29634661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26359184 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9761130 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 31129386 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31129386 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 31129386 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 29087166 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29087166 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22385927 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17890994 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15272537 — Biomarker: ASCL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASCL1; ASH1; BHLHA46; HASH1
Study 10465074 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30918030 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 28124514 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 22496767 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 17445347 — Biomarker: APEX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 17445347 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 17445347 — Biomarker: ERCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC2; XPD; XPDC
Study 17445347 — Biomarker: DNA repair endonuclease XPF
Type: Predictive Biomarker (PRD)
Genes: ERCC4; ERCC11; XPF
Study 17445347 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 17445347 — Biomarker: OGG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OGG1; MMH; MUTM; OGH1
Study 17445347 — Biomarker: XPAC mRNA
Type: Predictive Biomarker (PRD)
Genes: XPA; XPAC
Study 17445347 — Biomarker: XPC mRNA
Type: Predictive Biomarker (PRD)
Genes: XPC; XPCC
Study 17445347 — Biomarker: XRCC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: XRCC3
Study 17445347 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 17445347 — Biomarker: CYP1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A1
Study 15340356 — Biomarker: ECE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ECE1
Study 11588025 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 9699585 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25486415 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15291857 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10828670 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 8650418 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1628135 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27898234 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 23534952 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21570352 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 19225525 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10620550 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18042519 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 11821457 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 7960016 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30475968 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study 30475968 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20463104 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20463104 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8704017 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 1888422 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6353878 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29846794 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22985564 — Biomarker: IL21
Type: Predictive Biomarker (PRD)
Genes: Za11; IL-21
Study 18672991 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 10501818 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10501818 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 2006656 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23722352 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 23722352 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 11442188 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31444706 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9382207 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 9382207 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9382207 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 3093305 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 23289187 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19926918 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 19926918 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19926918 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18230353 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10498402 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 10498402 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10498402 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 12536532 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24309336 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10664112 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10664112 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2