AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 20657034 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20657034 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19583878 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8190431 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28345432 — Biomarker: FGR mRNA
Type: Predictive Biomarker (PRD)
Genes: FGR; SRC2
Study 24865782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15857519 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 15857519 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25123060 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25123060 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14593453 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11810130 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 2609241 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 31756536 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 20848528 — Biomarker: CTLA4
Type: Predictive Biomarker (PRD)
Genes: CD152; CD; GSE; CTLA-4
Study 27352486 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 20502909 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17728050 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 17728050 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 10768630 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 8829312 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8829312 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19960492 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 18728660 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15968676 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 15968676 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 12891211 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30217371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17584482 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17584482 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17584482 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 17584482 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 17584482 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 9871429 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 154747 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28403412 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21893693 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19352213 — Biomarker: FGB mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGB
Study 19352213 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11789278 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 11789278 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 11789278 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11789278 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 28215665 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23401923 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 18513526 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16580575 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10669338 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10669338 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 18690345 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18690345 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 15720047 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30795734 — Biomarker: FST mRNA
Type: Predictive Biomarker (PRD)
Genes: FST
Study 2658454 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 27605629 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 27605629 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 27605629 — Biomarker: Hepatitis A virus cellular receptor 1
Type: Safety Biomarker (SAF)
Genes: HAVCR1; KIM1; TIM1; TIMD1
Study 27605629 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20148806 — Biomarker: CCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR4; CMKBR4
Study 20148806 — Biomarker: CXCR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR3; GPR9
Study 20148806 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20148806 — Biomarker: ADAM11 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ADAM11; MDC
Study 20148806 — Biomarker: CCL22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 18719447 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16115358 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 10051075 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31807849 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 29084657 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29084657 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1417015 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 30797750 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 9660375 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 9660375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29401318 — Biomarker: SMAD3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMAD3; MADH3
Study 8436158 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 30418475 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 19632949 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 19632949 — Biomarker: CDH3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDH3; CDHP
Study 8031705 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8031705 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25894749 — Biomarker: LSS mRNA
Type: Predictive Biomarker (PRD)
Genes: LSS; OSC
Study 25459393 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11234740 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 12021520 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1835324 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31113987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25073939 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 25073939 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 21084399 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 21084399 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9706623 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 30571289 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 30571289 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 28214664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24456991 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22537824 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 17414805 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15858814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24439980 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22884040 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20972285 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20972285 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12741449 — Biomarker: NOS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOS2; NOS2A
Study 10574587 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 10574587 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10574587 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30391914 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25782451 — Biomarker: miR-409-3p
Type: Predictive Biomarker (PRD)
Genes: MIR409
Study 25156622 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9858319 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 29019297 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 22503722 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20435196 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6289856 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26879200 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15902741 — Biomarker: IGFBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP1; IBP1
Study 15902741 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 15902741 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 15902741 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 6401426 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30716509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26712474 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25161182 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17950801 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12089124 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10480520 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 24956454 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 17305652 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17305652 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 25448491 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23883653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19032600 — Biomarker: HSPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPB1; HSP27; HSP28
Study 31362999 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 21565490 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 21565490 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 8257447 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8257447 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 8257447 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23020133 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 23020133 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20124218 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12828169 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1639047 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 31766627 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22569241 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 17493526 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 17493526 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 17493526 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 17493526 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17493526 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 17493526 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 17493526 — Biomarker: FOXP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 15716708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7493424 — Biomarker: Nasal potential difference
Type: Pharmacodynamic Biomarker (PDY)
Study 30915963 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 21223512 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21223512 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21223512 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 21223512 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 21223512 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26269397 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25261913 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 12460326 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7014814 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 22490579 — Biomarker: Mitochondrial membrane potential
Type: Pharmacodynamic Biomarker (PDY)
Study 22490579 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 22490579 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 14583186 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 10553829 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28207527 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26180243 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23979955 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2985351 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26051802 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 31679359 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31679359 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31679359 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31679359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31679359 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31679359 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31679359 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27913695 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 26291797 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 17577032 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 29144812 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 24571582 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 19462276 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21121874 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24622804 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18812608 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 23270535 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23270535 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10512899 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10595045 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9973031 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28404531 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28404531 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25742716 — Biomarker: GHR mRNA
Type: Predictive Biomarker (PRD)
Genes: GHR
Study 19798097 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16487912 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16487912 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 16487912 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 10836728 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10836728 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30201408 — Biomarker: LPAR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LPAR1; EDG2; LPA1
Study 19713965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16449345 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 15033935 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 8025745 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 8025745 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25044795 — Biomarker: UCP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP2; SLC25A8
Study 25044795 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 25044795 — Biomarker: GSS mRNA
Type: Predictive Biomarker (PRD)
Genes: GSS
Study 25044795 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 25044795 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 25044795 — Biomarker: CDKN2A mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2A; CDKN2; MTS1
Study 25044795 — Biomarker: PPIA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPIA; CYPA
Study 25044795 — Biomarker: SOCS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOCS3; CIS3; SSI3
Study 25044795 — Biomarker: APEX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 25044795 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25044795 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22840549 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 20377532 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 8215790 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3525237 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 10579145 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 30412235 — Biomarker: MME mRNA
Type: Predictive Biomarker (PRD)
Genes: MME; EPN
Study 25157767 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 25157767 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19240178 — Biomarker: ABCC4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC4; MOATB; MRP4
Study 19240178 — Biomarker: ABCC5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC5; MRP5
Study 19240178 — Biomarker: ATP-binding cassette sub-family C member 11
Type: Predictive Biomarker (PRD)
Genes: ABCC11; MRP8