AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 26738271 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 2905154 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8989735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22775763 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22775763 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15615808 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3043077 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31931927 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31931927 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31931927 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31931927 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31931927 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12213435 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 9835004 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 7730602 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2521409 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23480456 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21619984 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 15223872 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 23751277 — Biomarker: SLCO2B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 23751277 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 23751277 — Biomarker: ABCG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 21281870 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10676602 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10676602 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24970869 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18688081 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 18688081 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 18688081 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 6377563 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30315178 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30315178 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7720759 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8800784 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23290081 — Biomarker: EDNRA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDNRA; ETA; ETRA
Study 17031013 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 9314645 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 31206501 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 29457585 — Biomarker: ID1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ID1; BHLHB24; ID
Study 23453439 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 19938199 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16934043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12628875 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 21982583 — Biomarker: CXADR mRNA
Type: Predictive Biomarker (PRD)
Genes: CXADR; CAR
Study 9613910 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9613910 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22088587 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 22088587 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22088587 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22088587 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 17143357 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 8200722 — Biomarker: N-acetylneuraminic acid
Type: Safety Biomarker (SAF)
Study 30349279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22491963 — Biomarker: MT2A mRNA
Type: Predictive Biomarker (PRD)
Genes: MT2A; CES1; MT2
Study 20634736 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18576898 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31049826 — Biomarker: NF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF2; SCH
Study 19149817 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15159498 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 31416745 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31416745 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29259181 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 7530641 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 2212968 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16461038 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6153834 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 31377905 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31377905 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25336921 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15661417 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 15661417 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 10087242 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7018726 — Biomarker: MERTK mRNA
Type: Predictive Biomarker (PRD)
Genes: MERTK; MER
Study 29084522 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 29084522 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23637005 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 1509550 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6838691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24949549 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 14996412 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14996412 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 31424395 — Biomarker: Beta-secretase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: BACE1; BACE; KIAA1149
Study 19141998 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19141998 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19141998 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12351466 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31865042 — Biomarker: HOXA9 mRNA
Type: Predictive Biomarker (PRD)
Genes: HOXA9; HOX1G
Study 19523690 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 28653586 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28653586 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24224449 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 3742049 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 28480658 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19383314 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 9795483 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 365214 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26620101 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 26620101 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 22212862 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15221206 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21471564 — Biomarker: Tubulin beta-3 chain
Type: Predictive Biomarker (PRD)
Genes: TUBB3; TUBB4
Study 15220243 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 15220243 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 15220243 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 15220243 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27568322 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 27568322 — Biomarker: MTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 27568322 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 27568322 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 20018286 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20018286 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18600215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2870352 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2870352 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 24827746 — Biomarker: GNB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNB3
Study 24827746 — Biomarker: ADRB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB3; ADRB3R; B3AR
Study 24827746 — Biomarker: UCP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP2; SLC25A8
Study 20590587 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 20590587 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 7734262 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 6940435 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30823948 — Biomarker: LIF mRNA
Type: Predictive Biomarker (PRD)
Genes: LIF; HILDA
Study 21334912 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 21334912 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21334912 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2973219 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 2973219 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29925472 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16023653 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16023653 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 16023653 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8889902 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1988237 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31797203 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31797203 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31797203 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31797203 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25970861 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 23660169 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17513945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31007226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25072610 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 25072610 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7631732 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 23222034 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 18155052 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18155052 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9008448 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 23935398 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 23935398 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10733537 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 22339102 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 16207547 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 24643104 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18664538 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1958451 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31789723 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 28650680 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 25037034 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25037034 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19936182 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14748901 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 11915781 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8761842 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8761842 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 8761842 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8761842 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8761842 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3838352 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24525654 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study 28086813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15259908 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15259908 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7875191 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21817806 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21817806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19702078 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19702078 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12843002 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 10934673 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study 21215201 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21215201 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21215201 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11139006 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9105223 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28495197 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16436132 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 29187901 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 29187901 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 8895037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30610026 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29395637 — Biomarker: ASPA mRNA
Type: Predictive Biomarker (PRD)
Genes: ASPA; ACY2; ASP
Study 29395637 — Biomarker: ITGA2B mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGA2B; GP2B; ITGAB
Study 29395637 — Biomarker: PDE4C mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE4C; DPDE1
Study 12163810 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 15606396 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11125881 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11125881 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 3180669 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31046812 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17673219 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17673219 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17673219 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27789938 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24665995 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22586173 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11097601 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 31906814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28784687 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18577531 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 18577531 — Biomarker: RAPGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 22115143 — Biomarker: MAP3K10 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP3K10; MLK2; MST
Study 11581545 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11581545 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25286455 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31786695 — Biomarker: TLR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR1; KIAA0012
Study 31786695 — Biomarker: TLR6 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR6
Study 28295989 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 16581477 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16581477 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9266878 — Biomarker: SPN mRNA
Type: Predictive Biomarker (PRD)
Genes: SPN; CD43
Study 2648152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16859579 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 26251005 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22313548 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 12131215 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7010854 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31390500 — Biomarker: APOC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOC3
Study 9040213 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7713100 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2455118 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29329042 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27035372 — Biomarker: CTLA4
Type: Predictive Biomarker (PRD)
Genes: CD152; CD; GSE; CTLA-4
Study 16820403 — Biomarker: SPAG11B mRNA
Type: Predictive Biomarker (PRD)
Genes: SPAG11B; EP2; HE2
Study 14563968 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 14563968 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 10891434 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34