AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31827687 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31827687 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31827687 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 28626088 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28626088 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28626088 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3057329 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 26346429 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19368965 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 11325461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7934158 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29194612 — Biomarker: miR-16
Type: Safety Biomarker (SAF)
Study 29194612 — Biomarker: miR-17
Type: Predictive Biomarker (PRD)
Genes: MIR17
Study 29194612 — Biomarker: miR-128
Type: Safety Biomarker (SAF)
Study 29194612 — Biomarker: miR-132
Type: Pharmacodynamic Biomarker (PDY)
Genes: MIR132
Study 29194612 — Biomarker: miR-155
Type: Safety Biomarker (SAF)
Genes: MIR155
Study 29194612 — Biomarker: miR-15a
Type: Safety Biomarker (SAF)
Genes: MIR15A
Study 29194612 — Biomarker: miR-106b
Type: Predictive Biomarker (PRD)
Genes: MIR106B
Study 29194612 — Biomarker: miR-31
Type: Predictive Biomarker (PRD)
Genes: MIR31
Study 29194612 — Biomarker: miR-150
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR150
Study 28753849 — Biomarker: CYP17A1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CYP17A1; CYP17; S17AH
Study 28753849 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 18485309 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17175661 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 10883417 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 10883417 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30260551 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30260551 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27415448 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11577787 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 9164894 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9196864 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9196864 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9196864 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 9196864 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 1458789 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 1458789 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9334157 — Biomarker: MMRN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 8420041 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study 8420041 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30379749 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 28121470 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23832863 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18666468 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27283365 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26088042 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 11489026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8089244 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 22683294 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 22683294 — Biomarker: DSE mRNA
Type: Predictive Biomarker (PRD)
Genes: DSE; SART2
Study 19097507 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 15998785 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12122230 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31446153 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 31446153 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31446153 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 29064743 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 17136563 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17136563 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 17136563 — Biomarker: KLRD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRD1; CD94
Study 6384455 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 21275630 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 16730271 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 29791971 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 21684012 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 21684012 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 14581723 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29475874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 282073 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25569647 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 25569647 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23052625 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23052625 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 9140680 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1646068 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 21130598 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25960403 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25960403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25960403 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24091175 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24091175 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21779829 — Biomarker: LSR mRNA
Type: Predictive Biomarker (PRD)
Genes: LSR; ILDR3; LISCH
Study 19786444 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15349783 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15349783 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 11117271 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 7505143 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31491931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10874261 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10874261 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8517425 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8582495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26394017 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17268121 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30914312 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 10874989 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31054246 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 31054246 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 31054246 — Biomarker: GPR55 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPR55
Study 31054246 — Biomarker: GPR119 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPR119
Study 29026123 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 12487321 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29050753 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 26086183 — Biomarker: NUBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUBP1; NBP; NBP1
Study 12818310 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17346248 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 2136969 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 14966737 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9455079 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3285834 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25560051 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 25560051 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 25560051 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 23067229 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20671032 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18520293 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9748012 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 31714895 — Biomarker: NOS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOS2; NOS2A
Study 31714895 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26757835 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26757835 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20185006 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20185006 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20185006 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20185006 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8198976 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 19196360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15233977 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 20345865 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31042791 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17211855 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 17211855 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 15356026 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7989710 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 1600494 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 24244635 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24244635 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 24244635 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 18347654 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18347654 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 21999723 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 10737284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3260082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30169740 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 22707261 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19033449 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1130437 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30240936 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 25547033 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 20405236 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20146881 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20146881 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20146881 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 20146881 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2752395 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 2752395 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31646668 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20584756 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20584756 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 9182472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9182472 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30657017 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 30657017 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30657017 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28806917 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 19422140 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16417639 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 15246645 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9573428 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31654276 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28077584 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 19398602 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 19398602 — Biomarker: ABCG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG1; ABC8; WHT1
Study 10563141 — Biomarker: Alpha-glutathione S-transferase
Type: Safety Biomarker (SAF)
Study 29653686 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 16261774 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18076218 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 11136298 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 10599601 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 7592202 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 1850576 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8724116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21705084 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 28801309 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 28801309 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24398758 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 6230892 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24776325 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 24776325 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10219067 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10219067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25863797 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19615989 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 16705849 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16540949 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16540949 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16540949 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 21827441 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 21827441 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 21827441 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 17873492 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8955576 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 24924267 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 9040574 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10573546 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 8733734 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 31676222 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28687275 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 22416600 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22416600 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9550532 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9550532 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 9550532 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9550532 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26630216 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26630216 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10746484 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10746484 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20214205 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17249526 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17249526 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31520576 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 31520576 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 31520576 — Biomarker: HTR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2A; HTR2
Study 31520576 — Biomarker: HTR2C mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2C; HTR1C
Study 25134002 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19139296 — Biomarker: SCN1A mRNA
Type: Predictive Biomarker (PRD)
Genes: SCN1A; NAC1; SCN1
Study 17672892 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27043952 — Biomarker: CGAS mRNA
Type: Predictive Biomarker (PRD)
Genes: CGAS; C6orf150; MB21D1
Study 23869890 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23869890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16815783 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7792744 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 2143638 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7438385 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29891906 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15838676 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10756890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30150128 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)