AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24980672 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24980672 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14871429 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 27316489 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 18841790 — Biomarker: TLR9
Type: Predictive Biomarker (PRD)
Genes: CD289
Study 10399449 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7551323 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7033789 — Biomarker: Serum alkaline phosphatase and bilirubin
Type: Surrogate Endpoint (SUR)
Study 7033789 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18083374 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 11934652 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11934652 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9257425 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8400081 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 3037835 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19025306 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 30106834 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 7509380 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17162433 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17162433 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17162433 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10426453 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2194509 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2194509 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22101760 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10999807 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 18356697 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18356697 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31905885 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26575248 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23972865 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2525337 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2525337 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15472200 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25874530 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 25874530 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 29935544 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12227400 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10525709 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10525709 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 10525709 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 27695980 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 20298784 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20298784 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18796622 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 18796622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18796622 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2523645 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 356497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 356497 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 356497 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 356497 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 356497 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31848551 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21209030 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24781851 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24781851 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1877516 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1877516 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1877516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6401357 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29698019 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 9488498 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 30274344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30274344 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30274344 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12751804 — Biomarker: SLC10A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC10A3; DXS253E; P3
Study 30796508 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30796508 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29406428 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26523653 — Biomarker: NR3C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR3C2; MCR; MLR
Study 23733256 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 20142024 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 20142024 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15659491 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 15659491 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 103378 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31577104 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 21221990 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 15741212 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28705885 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 31808659 — Biomarker: TNF-related weak inducer of apoptosis
Type: Predictive Biomarker (PRD)
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study 31808659 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28202370 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 21970138 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15063762 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 15063762 — Biomarker: CXCR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR2; IL8RB
Study 15063762 — Biomarker: IL10RA mRNA
Type: Predictive Biomarker (PRD)
Genes: IL10RA; IL10R
Study 15063762 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 15063762 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 15063762 — Biomarker: NFKB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NFKB1
Study 15063762 — Biomarker: GRAP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRAP2; GADS; GRB2L; GRID
Study 15063762 — Biomarker: CABIN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CABIN1; KIAA0330
Study 15063762 — Biomarker: IFI27 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFI27
Study 15063762 — Biomarker: TNFRSF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1A; TNFAR; TNFR1
Study 15063762 — Biomarker: ALDOB mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDOB; ALDB
Study 9815721 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9815721 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9815721 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11865269 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3622543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19325469 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19325469 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 9200375 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 25904650 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25904650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19897276 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2977272 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 17909844 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 10471520 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8566259 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7872224 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7872224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7872224 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20535796 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11000341 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 11000341 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11000341 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 1377290 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 24911353 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24911353 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20103722 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 14516890 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14516890 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23296149 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 9827976 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2506834 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 29443750 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24096366 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 22154766 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 3512121 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 26448147 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26448147 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19298916 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 19298916 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3499456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30177465 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15180756 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21600388 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30266677 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 16735934 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16735934 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9846844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27631562 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24722494 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20736456 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 20736456 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 20736456 — Biomarker: BCL6 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 20736456 — Biomarker: IRF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRF4; MUM1
Study 9845803 — Biomarker: Trefoil factor 3
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TFF3; ITF; TFI
Study 2158869 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 31953483 — Biomarker: RRAD mRNA
Type: Predictive Biomarker (PRD)
Genes: RRAD; RAD
Study 26077267 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 26077267 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 10690871 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10179578 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 31499515 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 27707818 — Biomarker: ERCC2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MAG; EM9; MGC102762; MGC126218; MGC126219
Study 22337905 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28434387 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 25385024 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 19526753 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19526753 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 16286908 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 1762311 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1762311 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 1762311 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 1762311 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 31703023 — Biomarker: Clusterin
Type: Safety Biomarker (SAF)
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 22865498 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9590144 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27930609 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26022948 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12470401 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9867064 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9867064 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9867064 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22799129 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 31735500 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27853882 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 27853882 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 27853882 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25885661 — Biomarker: SPARC mRNA
Type: Predictive Biomarker (PRD)
Genes: SPARC; ON
Study 17846293 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 30354969 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24984683 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18554989 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16869716 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 16869716 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 12540501 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 18194120 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7549900 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2181941 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 26228714 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26228714 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 26228714 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21423253 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17672185 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9031450 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 9031450 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9031450 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 28537849 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23570589 — Biomarker: KDM5D mRNA
Type: Predictive Biomarker (PRD)
Genes: KDM5D; HY; HYA; JARID1D; KIAA0234; SMCY
Study 21605733 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11785282 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11785282 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11785282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7834934 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3413270 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29802953 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 29802953 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 11282760 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 9203228 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23835546 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18156649 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 22329352 — Biomarker: FGFR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR3; JTK4
Study 22329352 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study 8665991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26842957 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20306569 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21762279 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18048463 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18048463 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 18048463 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 18048463 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 2166455 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19093122 — Biomarker: CNR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNR1; CNR
Study 17599307 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9508663 — Biomarker: GLI2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLI2; THP
Study 10211753 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10211753 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 113095 — Biomarker: HHEX mRNA
Type: Predictive Biomarker (PRD)
Genes: HHEX; HEX; PRH; PRHX
Study 10682561 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 10682561 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2526866 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 27389019 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22929989 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 31377052 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 31377052 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)