AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 29624887 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29624887 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15333465 — Biomarker: ERCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERCC2; XPD; XPDC
Study 15333465 — Biomarker: APEX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 15333465 — Biomarker: XRCC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: XRCC3
Study 11789775 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 30028478 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 14503058 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 14503058 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26631181 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23849625 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 22052266 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 16495194 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16495194 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16495194 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17109305 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11996958 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 9578185 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9578185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24158983 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15257186 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15257186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31615937 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31615937 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24690201 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 16322468 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 8781902 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 6372563 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 20007923 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20007923 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 25127090 — Biomarker: Urine free cortisol
Type: Surrogate Endpoint (SUR)
Study 15919695 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15919695 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9094887 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8104091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31323295 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12685513 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12411535 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 6761851 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 28740213 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21623963 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21623963 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 21623963 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21623963 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19042945 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 19042945 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 15718406 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2432009 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27849166 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 27849166 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 25061688 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 22726372 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21098580 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16351673 — Biomarker: GSS mRNA
Type: Predictive Biomarker (PRD)
Genes: GSS
Study 1752116 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 1752116 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 28356068 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28356068 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 28356068 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26921645 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 11506819 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 9743394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31028957 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19262499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8922197 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 26009799 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 19572829 — Biomarker: MAX mRNA
Type: Predictive Biomarker (PRD)
Genes: MAX; BHLHD4
Study 12888152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1873002 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26669919 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26669919 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23778432 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27401319 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27401319 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 27401319 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17968992 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 16221106 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17560254 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 17560254 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9331015 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22854954 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22854954 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20332484 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 17070962 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 15636137 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 26049975 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 26049975 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24332196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19112032 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 19112032 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 19112032 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19112032 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 19112032 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 19112032 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20890933 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9108642 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 8474201 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24588407 — Biomarker: MAP3K10 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP3K10; MLK2; MST
Study 23350899 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21813900 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 14564337 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6318224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29853235 — Biomarker: OPRM1
Type: Safety Biomarker (SAF)
Genes: MOR1; MOP
Study 22891212 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20587704 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20587704 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 7782965 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 16253719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16253719 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23271305 — Biomarker: USF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: USF1; BHLHB11; USF
Study 23271305 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23271305 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21645007 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10831287 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 10831287 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 20191485 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24845190 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 20844075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2296627 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31784904 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 31784904 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 31784904 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 31784904 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 17102644 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 26782102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25237048 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17664057 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 17664057 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 17664057 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30878999 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 30878999 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 30878999 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9249123 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8424497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24024323 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24024323 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21401941 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 1371323 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 9175948 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1493229 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 27144905 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 10950411 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 29726071 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 23924290 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 10867042 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9434064 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study 15840055 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7846294 — Biomarker: CCKAR
Type: Safety Biomarker (SAF)
Study 31721026 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31721026 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26362578 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26362578 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12509613 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11100963 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 26961114 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17681027 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17681027 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28968138 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 26223345 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17940203 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2192098 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22778317 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 18275764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15818105 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 15818105 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7793406 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29878947 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 24824548 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31808278 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29110753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23816967 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 22866006 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18752281 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17531723 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3003729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3003729 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29789130 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21765345 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21765345 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 18506008 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 10617696 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 26517576 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 16883904 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7910472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26417059 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 9022561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 302028 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 29179766 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29880288 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27823681 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18665826 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15942550 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12843352 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10770343 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1815423 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6139422 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 6139422 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 27009061 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19395584 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 19395584 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19395584 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11208829 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 11208829 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7848401 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7848401 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8857250 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 8857250 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 8857250 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17962589 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10652038 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 6494106 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26346122 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 23707331 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23707331 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18257813 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 18257813 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18257813 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 18257813 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 31207169 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 15844579 — Biomarker: SPN mRNA
Type: Predictive Biomarker (PRD)
Genes: SPN; CD43
Study 15844579 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 15844579 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 15844579 — Biomarker: Th2 cell
Type: Safety Biomarker (SAF)
Study 2503375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20927554 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11771654 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28449205 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28449205 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23727002 — Biomarker: TLR9
Type: Predictive Biomarker (PRD)
Genes: CD289
Study 21732272 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 8550249 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 744812 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23490325 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 21806770 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21806770 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)