AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 22243564 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18581941 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25662861 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 10611136 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 29381993 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21208909 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21208909 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 21208909 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 21208909 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1359998 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 1359998 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 460026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20805430 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18279051 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 18279051 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15689918 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 6320622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25895948 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 25895948 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 22735869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16350383 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9857535 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12858356 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 12858356 — Biomarker: TGFB1I1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TGFB1I1; ARA55
Study 10928252 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10928252 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 27383395 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 14764424 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3492975 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 22890910 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 16642920 — Biomarker: Hydroxyphenylpyruvate dioxygenase
Type: Safety Biomarker (SAF)
Genes: HPD; PPD
Study 1279288 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29459468 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23404724 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18057480 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 8875379 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8875379 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31335805 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27187101 — Biomarker: RAB11FIP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAB11FIP1; RCP
Study 22522918 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 20127230 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21161742 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21161742 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 31838148 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 26125923 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26125923 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26125923 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 22775239 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 21156319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29900565 — Biomarker: OSM mRNA
Type: Predictive Biomarker (PRD)
Genes: OSM
Study 29900565 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 24325778 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24325778 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 23038702 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19301936 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19301936 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19301936 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21529957 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12451325 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2172178 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30477789 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 20575400 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10824236 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25339455 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 22678562 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 18188658 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12029990 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2455141 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11004028 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23635012 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23635012 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23635012 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23635012 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17058225 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9475650 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9475650 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 2239903 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20729619 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 6112411 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29454587 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29454587 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 24134405 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 24134405 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 1670591 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6606153 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 20380653 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 20380653 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 20380653 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 8214416 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 24206869 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16009884 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 10069556 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 9700034 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 15366324 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14992906 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 31095973 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 21088862 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29286560 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28043418 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 18805335 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 7951008 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30120478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20096399 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 18202581 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 10943584 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 26259517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19583742 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 11059637 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8729667 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 1362888 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 30425105 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 30425105 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 19289623 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17239712 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 9132031 — Biomarker: PLB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLB1; PLB
Study 20686900 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 12521655 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 22948416 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12700707 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 12959290 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 3475429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17921381 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16140232 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 20428608 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 20428608 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18803991 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 6662724 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 28122931 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25689146 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 8252492 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 21791491 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21791491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3276865 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26047957 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24018103 — Biomarker: SLC18A2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC18A2; SVMT; VMAT2
Study 2417648 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26858092 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23545909 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 18405146 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 7560474 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7141686 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 4056259 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29461654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16791287 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16791287 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30445718 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 12823643 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 12823643 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10910802 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 8955969 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16281062 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 16281062 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8605558 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 4087290 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29740768 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 19295388 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15055251 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15055251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30653262 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 30653262 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 23295789 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 15645954 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15645954 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15645954 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15645954 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15645954 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30184091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23184077 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20352618 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25623462 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25623462 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 25623462 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22827780 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22827780 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22827780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9702472 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 25974723 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 18445174 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16564934 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1536441 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20566677 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 12528325 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12528325 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8124121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28651927 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8362997 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12078939 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9698776 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9698776 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30629187 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30629187 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 30629187 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28396887 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 28396887 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 24339703 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24339703 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16844625 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16844625 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16844625 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12727963 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8853138 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 31587950 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 24639426 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 24639426 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 1512341 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6421013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27041244 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27041244 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27041244 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 22010847 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22010847 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22010847 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 20467879 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17880478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17880478 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10402248 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 8626261 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29179666 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29179666 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29179666 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24828621 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9599191 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8023348 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21518686 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29731160 — Biomarker: AZIN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AZIN2; ADC; KIAA1945; ODCP
Study 23859303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8087937 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31779056 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 29851024 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26293163 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 22961832 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18559291 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 3970647 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20232751 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 10412269 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 10412269 — Biomarker: MDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM2
Study 10412269 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 28498207 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 23748819 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2