AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 28368340 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 28368340 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 28368340 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15856859 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2191978 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23768206 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 21665167 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 7589382 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25735561 — Biomarker: Mothers against decapentaplegic homolog 2
Type: Predictive Biomarker (PRD)
Genes: SMAD2; MADH2; MADR2
Study 15249794 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3533421 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 25487220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12228196 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 9589294 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7979858 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7979858 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30622099 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 28071865 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9289439 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study 29846693 — Biomarker: SHH mRNA
Type: Predictive Biomarker (PRD)
Genes: SHH
Study 21566548 — Biomarker: TLR2
Type: Predictive Biomarker (PRD)
Genes: TIL4; CD282
Study 19594648 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19594648 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11054523 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 11054523 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 25331894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30172037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25372582 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 9459113 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 3202925 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25951632 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 25951632 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 30195124 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30195124 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28418937 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 31393619 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 31393619 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 31393619 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30156033 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17316098 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9541124 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9078536 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 2667597 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 8317653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20452705 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 10090348 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10090348 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29450585 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15005325 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 8293750 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25555877 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25555877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11754399 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9282234 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8102213 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 3557779 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19820133 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7515453 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24610180 — Biomarker: TKTL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TKTL1; TKR; TKT2
Study 22584263 — Biomarker: AQP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP3
Study 10326953 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30706836 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25416329 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25066025 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 22210755 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22210755 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6337676 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25090264 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25090264 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 3330140 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 29802627 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 20663460 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19726355 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 19726355 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 30430294 — Biomarker: EMB mRNA
Type: Predictive Biomarker (PRD)
Genes: EMB
Study 27206266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11863124 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7591280 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 7591280 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24622423 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 24032205 — Biomarker: C4A mRNA
Type: Predictive Biomarker (PRD)
Genes: C4A; CO4; CPAMD2
Study 16466168 — Biomarker: CHM mRNA
Type: Predictive Biomarker (PRD)
Genes: CHM; REP1; TCD
Study 4019944 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30513433 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study 27106715 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 20091678 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18166199 — Biomarker: Survival motor neuron protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 8558634 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8558634 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8558634 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 1831394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10226860 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8764421 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20937312 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 16904536 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9025802 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 12115356 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 377476 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 21332729 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 15498085 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21739700 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10596307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3925887 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 30415298 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 15877874 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15877874 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10690292 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 17175181 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 6343726 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 9456163 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1013850 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28555198 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14626626 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11061656 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8168532 — Biomarker: SSB mRNA
Type: Predictive Biomarker (PRD)
Genes: SSB
Study 9407641 — Biomarker: ALPK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALPK1; KIAA1527; LAK
Study 24656944 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 3917678 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 30341345 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11817518 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9553478 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9553478 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 9553478 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8157729 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 30722696 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18222354 — Biomarker: KIF6 mRNA
Type: Predictive Biomarker (PRD)
Genes: KIF6; C6orf102
Study 18473981 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 9193330 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26614676 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15784032 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10323814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10323814 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31977643 — Biomarker: DIAPH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DIAPH2; DIA
Study 31188026 — Biomarker: SLC2A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A2; GLUT2
Study 31188026 — Biomarker: SLC47A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC47A1; MATE1
Study 31188026 — Biomarker: SLC47A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC47A2; MATE2
Study 31188026 — Biomarker: POU2F1 mRNA
Type: Predictive Biomarker (PRD)
Genes: POU2F1; OCT1; OTF1
Study 27290966 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22954842 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 21541462 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21541462 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11419884 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27676151 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24246116 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20569447 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 9438767 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9438767 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8586774 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2770272 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2770272 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 25813656 — Biomarker: XRN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: XRN1; SEP1
Study 25813656 — Biomarker: SEPTIN6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEPTIN6; KIAA0128; SEP2; SEPT6
Study 25813656 — Biomarker: SEPTIN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEPTIN3; SEP3; SEPT3
Study 20443395 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 31387606 — Biomarker: Beta-secretase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: BACE1; BACE; KIAA1149
Study 25305042 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25305042 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21229331 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 21229331 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16477259 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15140632 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14514574 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 14514574 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 14514574 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10880891 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 1570227 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 20382637 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20382637 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8860096 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31127611 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26810483 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17414592 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17414592 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30488952 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 22661278 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 30898134 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 30898134 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 30898134 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 30898134 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 28648477 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23331192 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31262924 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26880679 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15121021 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15121021 — Biomarker: New morphometric vertebral fractures
Type: Surrogate Endpoint (SUR)
Study 9461704 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 19931408 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9057170 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 30296537 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 7769502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7769502 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19566639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15292108 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 15292108 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 25421879 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 31498937 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31446994 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 26580275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23733488 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 19130041 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17998028 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 17998028 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 27264211 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 17540969 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2071264 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31672712 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 21244601 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21244601 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12538369 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8403515 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8403515 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 8403515 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 15738535 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 2445214 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21262888 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21262888 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9288302 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 29909698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28681550 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17460370 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7955239 — Biomarker: RITA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RITA1; C12orf52; RITA; PSEC0043
Study 7955239 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 17054858 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10801994 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22732469 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9508182 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31214836 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31214836 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 31214836 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 27546817 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27546817 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2090833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2090833 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2090833 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31947784 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 24899570 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 11884002 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9498886 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29235894 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 29235894 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 29235894 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 29235894 — Biomarker: IRAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRAK1; IRAK
Study 26823552 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 7486086 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22576416 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19250558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19250558 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11074735 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20100958 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20100958 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 12241543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30391912 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2