AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 16780768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20815182 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 19083445 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12785023 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 10716475 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 10716475 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10716475 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10716475 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 10716475 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 24514907 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 24514907 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20808314 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11815322 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 24906976 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24906976 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 17891043 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16866809 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27094801 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 18990766 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12859466 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26629812 — Biomarker: DSP mRNA
Type: Predictive Biomarker (PRD)
Genes: DSP
Study 21401662 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 8839728 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 31206358 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 26780033 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 24931900 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 24931900 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17921900 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 400246 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26158794 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 20202636 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 20202636 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 20202636 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 17921409 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12232562 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24119605 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 17602935 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9926153 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 31729990 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25391326 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 23105144 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21320217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12804346 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8888809 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 6210278 — Biomarker: BLM mRNA
Type: Predictive Biomarker (PRD)
Genes: BLM; RECQ2; RECQL3
Study 11521914 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 7978412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9954 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23055051 — Biomarker: SLC9A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC9A1; APNH1; NHE1
Study 23055051 — Biomarker: TLX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLX2; HOX11L1; NCX
Study 23055051 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 10616841 — Biomarker: SLC12A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC12A3; NCC; TSC
Study 9156268 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 9156268 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 9156268 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 30241504 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30241504 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30241504 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 15915352 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 24219860 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 24219860 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 22808810 — Biomarker: IPP mRNA
Type: Predictive Biomarker (PRD)
Genes: IPP; KLHL27
Study 16786236 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16786236 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12539556 — Biomarker: HSPA1B mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA1B; HSP72
Study 9397242 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 9397242 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2822298 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29557858 — Biomarker: SNAP25 mRNA
Type: Predictive Biomarker (PRD)
Genes: SNAP25; SNAP
Study 18200024 — Biomarker: TTN mRNA
Type: Predictive Biomarker (PRD)
Genes: TTN
Study 15994288 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 8558209 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25673979 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 25673979 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 20052352 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 20052352 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17610534 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 12366619 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12366619 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12366619 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12366619 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 7576743 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 19166694 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15057738 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21992747 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 21992747 — Biomarker: IDE mRNA
Type: Predictive Biomarker (PRD)
Genes: IDE
Study 21992747 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 12551742 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 28718073 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 24152824 — Biomarker: miR-106b
Type: Predictive Biomarker (PRD)
Genes: MIR106B
Study 7979855 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25782227 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 29877199 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9159561 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 3655310 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11903319 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21611728 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 16351767 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 29151102 — Biomarker: ABCG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 29151102 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study 29151102 — Biomarker: MRP2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ABCC2; DJS; cMRP
Study 25272194 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19471949 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 19471949 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 19471949 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 19471949 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 10550446 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10550446 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21929736 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9778325 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 28328159 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25754254 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24402015 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9323940 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7954035 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26855568 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 16286173 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 26917577 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9469362 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7630200 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 20980201 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20980201 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17464690 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 30677465 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 11561769 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 30630803 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30630803 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26614548 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 25348723 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25885506 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25885506 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16248471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10097253 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 10097253 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17457187 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study 11361053 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31051499 — Biomarker: TERT mRNA
Type: Predictive Biomarker (PRD)
Genes: TERT; EST2; TCS1; TRT
Study 31051499 — Biomarker: WRAP53 mRNA
Type: Predictive Biomarker (PRD)
Genes: WRAP53; TCAB1; WDR79
Study 27488933 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 27488933 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 19808911 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 304478 — Biomarker: PRCP mRNA
Type: Predictive Biomarker (PRD)
Genes: PRCP; PCP
Study 27176449 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27176449 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12054164 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7767551 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 2181102 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19476631 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15677729 — Biomarker: AMPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMPD1
Study 7613098 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 7613098 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 2620952 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15562040 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12092185 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 7942489 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28628402 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28628402 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 24273887 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18971536 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18971536 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 18971536 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10739171 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 2951198 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26991772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1511712 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 1511712 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 31383985 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22008919 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22008919 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22008919 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 22008919 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 22008919 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 22410289 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19508973 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19508973 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30170304 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30170304 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12140349 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7589767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22838386 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17439512 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 30653423 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 30429461 — Biomarker: FGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF2; FGFB
Study 11874925 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 2139523 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 22300528 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 22300528 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22300528 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 22300528 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 19918047 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16959916 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 2691174 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29245361 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17129461 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 30557693 — Biomarker: ALAD mRNA
Type: Predictive Biomarker (PRD)
Genes: ALAD
Study 21749907 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 21749907 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 15249503 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 3071588 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3071588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16861404 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 15309453 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9251504 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9251504 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 30928954 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 16269957 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7026094 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 28893415 — Biomarker: Derived neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 28893415 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 26166613 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 7621842 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15595587 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19046094 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19046094 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 19046094 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26181707 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24143917 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 24628789 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 22459310 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12383572 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 10420746 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6716222 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 24498853 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 16236737 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8845088 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8845088 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30856 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25466493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21117970 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21117970 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21117970 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21117970 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16717336 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15549367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8483989 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20433766 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12904324 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10370739 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6836710 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25088287 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25088287 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19589793 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 28003500 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28003500 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9663912 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16303008 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 20849805 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10