AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 28566524 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 28566524 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25862517 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19921983 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 16432265 — Biomarker: MT2A mRNA
Type: Predictive Biomarker (PRD)
Genes: MT2A; CES1; MT2
Study 9039547 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23954085 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 18671147 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9864001 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 9864001 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 9864001 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23954165 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 16774103 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 14728888 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 20381672 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 15990457 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 15990457 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15526508 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7782727 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 7782727 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21807759 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 24225233 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 15789123 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 19189940 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 16925952 — Biomarker: DCC mRNA
Type: Predictive Biomarker (PRD)
Genes: DCC; IGDCC1
Study 16925952 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 12698087 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 12698087 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8637441 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 1455006 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 1455006 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 30248943 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23922377 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 8004580 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 2509214 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 25103176 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22674570 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 22674570 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 22674570 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 22674570 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 19597081 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 11718678 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9752889 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2455740 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 2455740 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26259542 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18365224 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 27563670 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 27563670 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 16059992 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 6469443 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21179732 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 16188898 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 16188898 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 1705274 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31116114 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 20094823 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 20094823 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 19232940 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11427213 — Biomarker: ACAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAT1; ACAT; MAT
Study 11427213 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11427213 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11427213 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18667807 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17141859 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 30036739 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 24977690 — Biomarker: XIAP mRNA
Type: Predictive Biomarker (PRD)
Genes: XIAP; API3; BIRC4; IAP3
Study 16002965 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 12218525 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8725976 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1890156 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20496732 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20496732 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 20496732 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 20496732 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12218722 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28306329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25319752 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 12687466 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 22967105 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 19005477 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17289891 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27325226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 804914 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 30796109 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 3815266 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 4077235 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4077235 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 4077235 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30016983 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 17634487 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 10517273 — Biomarker: SEMG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEMG1; SEMG
Study 8730115 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1862156 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 26408420 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 26408420 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26408420 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26408420 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 26408420 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10481500 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7116662 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7116662 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 7116662 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 29147968 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 29147968 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 24879975 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23859257 — Biomarker: CXADR mRNA
Type: Predictive Biomarker (PRD)
Genes: CXADR; CAR
Study 1345218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29414827 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7595716 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 728485 — Biomarker: HDC mRNA
Type: Predictive Biomarker (PRD)
Genes: HDC
Study 728485 — Biomarker: LUM mRNA
Type: Predictive Biomarker (PRD)
Genes: LUM; LDC; SLRR2D
Study 27346437 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11130523 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11130523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30019249 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29099521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29099521 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9833848 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2633019 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25375836 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16883264 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8214491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25026287 — Biomarker: WT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WT1
Study 6832623 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30207587 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16728451 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8834657 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 29863586 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 29863586 — Biomarker: CASP9
Type: Predictive Biomarker (PRD)
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 22571394 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22571394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19875481 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10582974 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30389952 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 21385196 — Biomarker: ALOX5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALOX5; LOG5
Study 21385196 — Biomarker: LTA4H mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA4H; LTA4
Study 20370845 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 231374 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26008855 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21725873 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21725873 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21725873 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21725873 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21725873 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 21725873 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 4079660 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 30204698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17004259 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20798154 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19057270 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 30135032 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 24801511 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 18322633 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 12438293 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 29068756 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15801332 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8579082 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24091128 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24091128 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21846852 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 11738123 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11738123 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9740604 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8147338 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25424929 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 22456294 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 10573067 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27309266 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 2744731 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21447470 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 15274665 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9428580 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9428580 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23213055 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 23213055 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21982456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16525857 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 11359657 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 25573021 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 19709658 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 19709658 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 19709658 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21871056 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 10705173 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 10705173 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31531949 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 25200587 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8970416 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1597846 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19716142 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 19716142 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 12826696 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 20011859 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17257460 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10840295 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26876722 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10069869 — Biomarker: CAMP mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMP; CAP18; FALL39; HSD26
Study 10069869 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28872734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26197184 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 21368590 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21368590 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 3058133 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23549993 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 17207378 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17207378 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 14586044 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30400924 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26967321 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 19539384 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 8129130 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31002110 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 25771840 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26510186 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23413042 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 31642066 — Biomarker: FOXM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXM1; FKHL16; HFH11; MPP2; WIN
Study 6615674 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 23298885 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 16870008 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 23225445 — Biomarker: MNT mRNA
Type: Predictive Biomarker (PRD)
Genes: MNT; BHLHD3; ROX
Study 23225445 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20664964 — Biomarker: ANXA10 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANXA10; ANX14
Study 16301236 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2719894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2719894 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 31213783 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26408274 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26408274 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23237136 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 11521725 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9220306 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 30634208 — Biomarker: BTLA mRNA
Type: Predictive Biomarker (PRD)
Genes: BTLA
Study 30634208 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30634208 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30634208 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30634208 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 22508307 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 7669486 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 7669486 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 25968008 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)