AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 18468748 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 17000967 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12853381 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 12853381 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 10928765 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19040374 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26282839 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 19597720 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 2692810 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11304774 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27323446 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 27323446 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 27323446 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9162315 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3925656 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20332351 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15716701 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 15716701 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15716701 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8523379 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8523379 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17854661 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 15078748 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 3141856 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 20506261 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 2853731 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24524605 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 28265014 — Biomarker: HSPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPB1; HSP27; HSP28
Study 28265014 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 11344347 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 7910229 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27430332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16961684 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 11083258 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9157579 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21916526 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 20539277 — Biomarker: GNB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNB3
Study 18294268 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 16047459 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8536776 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1775604 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9030833 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 9030833 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28162769 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25884885 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9880129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23499145 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11762415 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 2564563 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 7631298 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1849536 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28736511 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28408635 — Biomarker: SLC25A20 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A20; CAC; CACT
Study 26975625 — Biomarker: DMTN mRNA
Type: Predictive Biomarker (PRD)
Genes: DMTN; DMT; EPB49
Study 20175431 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17471993 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17471993 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 17471993 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 15955104 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28545998 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28545998 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19781835 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19781835 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11781670 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31921171 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 31921171 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 26797725 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22566588 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20439216 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1708037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29734777 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24941177 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24941177 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21805328 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8390340 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8390340 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31072380 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 25243962 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 25243962 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22007735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20448634 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 20448634 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20448634 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 7743571 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1559299 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 3876763 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23361591 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23361591 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19845233 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 19845233 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11340314 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 9404414 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8200011 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 22730912 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 30787666 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 8031733 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8031733 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25619410 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23789212 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23789212 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 23789212 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23789212 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23789212 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6343164 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 17294225 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 17294225 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17294225 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7911057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2843201 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2843201 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21227010 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 21227010 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26572788 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19843672 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12623938 — Biomarker: MTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 12623938 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9115051 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 9115051 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 15339769 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25803666 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15189292 — Biomarker: RHD mRNA
Type: Predictive Biomarker (PRD)
Genes: RHD
Study 25505013 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 24588965 — Biomarker: miR-124
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20455988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28338223 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 19939653 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19939653 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19939653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10910028 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9341968 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 3022512 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3022512 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3938935 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16956824 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 15329007 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 15329007 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 20387250 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20387250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10805056 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27302510 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8758093 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8758093 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20554790 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24219579 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 14504184 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14504184 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 11099761 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 27015578 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24662864 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24662864 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8569975 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 28383400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24078335 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 24078335 — Biomarker: RANGAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RANGAP1; KIAA1835; SD
Study 19204301 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15045504 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 12654211 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28791787 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25293480 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20226843 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 8831918 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 8831918 — Biomarker: HES1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HES1; BHLHB39; HL; HRY
Study 27888575 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15312097 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 27439969 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 27439969 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18271842 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 15693603 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 6990946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26476086 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2724027 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 24829088 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 24829088 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 22689678 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 22689678 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 16087995 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30689664 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 28903122 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24793535 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22551909 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 7598995 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 7598995 — Biomarker: BSN mRNA
Type: Predictive Biomarker (PRD)
Genes: BSN; KIAA0434; ZNF231
Study 23294500 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18997444 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9231890 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9231890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29043411 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19486119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8320430 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25023786 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 22960764 — Biomarker: STAT5A mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT5A; STAT5
Study 22960764 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18362764 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 25156987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25156987 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6164480 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 6164480 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 27777261 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10681340 — Biomarker: PCLAF mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 9192194 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30073585 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23318610 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15939519 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31530055 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31530055 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22858806 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19203563 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15172263 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 8462317 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study 30145817 — Biomarker: LGALSL mRNA
Type: Predictive Biomarker (PRD)
Genes: LGALSL; GRP; HSPC159
Study 10403616 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7720941 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 2039640 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27631821 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26445777 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 26445777 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31339677 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28182218 — Biomarker: CPD mRNA
Type: Predictive Biomarker (PRD)
Genes: CPD
Study 19519298 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 3806153 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25494205 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25494205 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22118569 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 2889306 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 16409560 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16409560 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9480237 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 8201970 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 22313587 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 12898439 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12898439 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 12898439 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 2772038 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 799927 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31864519 — Biomarker: PGP mRNA
Type: Predictive Biomarker (PRD)
Genes: PGP
Study 1327051 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1327051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28453765 — Biomarker: CCL20 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL20; LARC; MIP3A; SCYA20
Study 28453765 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26641456 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 29528792 — Biomarker: MAP2K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K1; MEK1; PRKMK1
Study 28126333 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 8944697 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 8944697 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP