AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31519550 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 7755941 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 7755941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21723554 — Biomarker: IPP mRNA
Type: Predictive Biomarker (PRD)
Genes: IPP; KLHL27
Study 21723554 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18986246 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26530543 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 21195291 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 9252710 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9252710 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2531608 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17159824 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 9383183 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29397354 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 29397354 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 12420826 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8787036 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 1659934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29652544 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28577670 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 26031292 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 26031292 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 29615003 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20815080 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19128246 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 16787141 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 8781854 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 3883732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20150290 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18560257 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 18560257 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25529904 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25529904 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21412057 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21412057 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19469829 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 16602327 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 16602327 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 10432474 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 2404502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30379826 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 30379826 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 30379826 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 27627194 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 22968888 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 20335355 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 10361111 — Biomarker: KDM5D mRNA
Type: Predictive Biomarker (PRD)
Genes: KDM5D; HY; HYA; JARID1D; KIAA0234; SMCY
Study 7595711 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25225715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23510493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16861943 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 16861943 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 29426348 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 20233196 — Biomarker: EDNRA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDNRA; ETA; ETRA
Study 20233196 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 25192259 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25192259 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20919666 — Biomarker: BCAR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCAR1; CAS; CASS1; CRKAS
Study 20919666 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 19954476 — Biomarker: Angiopoietin-1
Type: Monitoring Biomarker (MOI)
Genes: ANGPT1; KIAA0003
Study 19954476 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 9205819 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31308209 — Biomarker: GCA mRNA
Type: Predictive Biomarker (PRD)
Genes: GCA; GCL
Study 31308209 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 19294387 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17709456 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15563362 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 25016780 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25016780 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25016780 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20002646 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 17353513 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 17353513 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14729863 — Biomarker: APOA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOA5; RAP3; UNQ411/PRO773
Study 14729863 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2198911 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 2198911 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2198911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 219509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26541570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24568963 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15888205 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 29417371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22576327 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 1716558 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 10547079 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1855357 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1855357 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1389945 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 24169821 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 24169821 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30070742 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19212269 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19212269 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19212269 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23720354 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 20644123 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 16863695 — Biomarker: KCNK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNK3; TASK; TASK1
Study 23839254 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 22300693 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22300693 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2483580 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 27861991 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 27861991 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25651476 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 24335445 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22659487 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 20226558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15772571 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15772571 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2148148 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19751435 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17355820 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 7840912 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27549242 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 24244725 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 10486668 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12621364 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 10781119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27002448 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 24521561 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22901350 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 8282360 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29628483 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29628483 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27886619 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 22766394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18331816 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 9174486 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21169815 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 21169815 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11320559 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 9134651 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 2889501 — Biomarker: ASPRV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASPRV1; SASP
Study 17559758 — Biomarker: MEA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MEA1; MEA
Study 26825650 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 22796513 — Biomarker: TKTL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TKTL1; TKR; TKT2
Study 15886663 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 6628792 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 30384885 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30384885 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27044332 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 27044332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26111150 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 26111150 — Biomarker: ADRB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB1; ADRB1R; B1AR
Study 26111150 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23130583 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 19040615 — Biomarker: TNFRSF10A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 19040615 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 19040615 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 10561144 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 10561144 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8991468 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30623907 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28947757 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 14551368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10841169 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1301246 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 1301246 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24170749 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 11783269 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 384920 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 21735693 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 21735693 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 20104753 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25440796 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 25440796 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25440796 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22753208 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15964445 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 1283586 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6133987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26254237 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 24870115 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11486156 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26828801 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 18040672 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 7598139 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 870547 — Biomarker: NR3C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR3C2; MCR; MLR
Study 28259608 — Biomarker: MYCN mRNA
Type: Predictive Biomarker (PRD)
Genes: MYCN; BHLHE37; NMYC
Study 26553894 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 16539560 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 12649401 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12649401 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8055999 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31885802 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17598007 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 2866965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29412077 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29412077 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17487767 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 30894455 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23383171 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17085674 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 15101466 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9310536 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3540212 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 19846273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15666120 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10526278 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 6295132 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6295132 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31442303 — Biomarker: CX3CL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CX3CL1; FKN; NTT; SCYD1; A-152E5.2
Study 31442303 — Biomarker: CXCL1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 29354177 — Biomarker: SULT1E1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SULT1E1; STE
Study 29354177 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19505878 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8922801 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27271264 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27271264 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22360645 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 22360645 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 18707986 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18707986 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9404698 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 9404698 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 20385929 — Biomarker: APLNR mRNA
Type: Predictive Biomarker (PRD)
Genes: APLNR; AGTRL1; APJ
Study 14986815 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 2413519 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31372803 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31372803 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 31372803 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27251406 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 27251406 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 27251406 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23359968 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 23359968 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20407369 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2265765 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7442534 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30852021 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28384521 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study 28384521 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 17762645 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8777381 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 29429253 — Biomarker: TERT mRNA
Type: Predictive Biomarker (PRD)
Genes: TERT; EST2; TCS1; TRT
Study 22682949 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30638154 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17084625 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 16270721 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 11801579 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)