AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 8420296 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8420296 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3749299 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28135883 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 23311248 — Biomarker: Lysosomal acid glucosylceramidase
Type: Pharmacodynamic Biomarker (PDY)
Genes: GBA1; GBA; GC; GLUC
Study 920252 — Biomarker: OTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 31713129 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31713129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15579515 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29888547 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 29888547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25119686 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22361399 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 7430504 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12424822 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7544524 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 6909683 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 21896198 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 12646340 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12646340 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10068342 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11039639 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8970607 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30176391 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 30176391 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26275787 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22465901 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 15905884 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7735336 — Biomarker: ABL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABL2; ABLL; ARG
Study 7735336 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 29150790 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23372142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21912808 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 21912808 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study 16646722 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 11025952 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8311271 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 3396573 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26603531 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22928779 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 9140674 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9140674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24040156 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 19318695 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 19318695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15576069 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 8066866 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18077012 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8320622 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31512487 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31512487 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24642648 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 24642648 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11867042 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 11867042 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11867042 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26527536 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 31805968 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12784700 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 9862579 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 12741422 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10971308 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19559965 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 19559965 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 17623745 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7966415 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 1632100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29695594 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 26847290 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22872468 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 20688261 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26684633 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24857299 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15809366 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15809366 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12182234 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1954179 — Biomarker: Epiregulin
Type: Safety Biomarker (SAF)
Genes: EREG
Study 25635593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1483491 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 29070503 — Biomarker: C1QTNF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: C1QTNF3; CTRP3; UNQ753/PRO1484
Study 12131247 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 12131247 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28115517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2920499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25516462 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 21247415 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20003300 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16150956 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26604072 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22408123 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 22408123 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22408123 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22408123 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 22408123 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22408123 — Biomarker: Chitinase-3-like protein 1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: CHI3L1
Study 26116264 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8664529 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1518670 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28687937 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28687937 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 25448925 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 23643425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19555395 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 19555395 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19555395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19555395 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9773262 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8005128 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 8005128 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31911249 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 28171710 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 31680085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24164872 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 2075773 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 6942648 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6942648 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30787601 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 30787601 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 25217039 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7019706 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22777113 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 22777113 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 22777113 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 22777113 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 17927497 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15837438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8180354 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 8180354 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 26939898 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 8382104 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 28712152 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 23816022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16936533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1651610 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 6321376 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6321376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19922681 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17257428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15508665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8591371 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24052987 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24052987 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 24052987 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9300248 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 17563335 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21427147 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 15464773 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 12792150 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10383596 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 8707338 — Biomarker: CD52 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD52; CDW52; HE5
Study 8707338 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8707338 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 8707338 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 8707338 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8707338 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 31340801 — Biomarker: Ribonucleoside-diphosphate reductase large subunit
Type: Predictive Biomarker (PRD)
Genes: RRM1; RR1
Study 24938580 — Biomarker: CPD mRNA
Type: Predictive Biomarker (PRD)
Genes: CPD
Study 22813436 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 22813436 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17602080 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 9101305 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12006419 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 22068866 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20663203 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20663203 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12021225 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28257169 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 28257169 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 23868188 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19622617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16963350 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10469292 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8834129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18058343 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 28974568 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23880908 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23880908 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23880908 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 31248461 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 31248461 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24977698 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21730307 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12117049 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 7539633 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7539633 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 7539633 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7539633 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25446057 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 25446057 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 27246689 — Biomarker: Vitamin K-dependent protein C
Type: Safety Biomarker (SAF)
Genes: PROC
Study 24525158 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 20579957 — Biomarker: SPTB mRNA
Type: Predictive Biomarker (PRD)
Genes: SPTB; SPTB1
Study 15814873 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12215585 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 12215585 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8704079 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23909911 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17116057 — Biomarker: SPARC mRNA
Type: Predictive Biomarker (PRD)
Genes: SPARC; ON
Study 29316186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18259973 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16293781 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16293781 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16293781 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11891095 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 30101910 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 20177349 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15764767 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 10603631 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 22192672 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9730795 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 3154631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 168650 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16957425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27896908 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 27896908 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 27896908 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 27896908 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17512160 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17512160 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 17512160 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 8961069 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8961069 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 8961069 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31712971 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 25018015 — Biomarker: LTA4H mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA4H; LTA4
Study 21079217 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21079217 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 21079217 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17081356 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 17081356 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 22155702 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19940276 — Biomarker: EPHX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPHX2
Study 12537671 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10725769 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 26618456 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 1302160 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25891210 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 17972053 — Biomarker: GNB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNB3
Study 17972053 — Biomarker: GNB3
Type: Predictive Biomarker (PRD)
Study 12475841 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 28121710 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7926290 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 28842574 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 28842574 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 21119031 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15016021 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)