AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 8201953 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 8201953 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 129002 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30230409 — Biomarker: AGL mRNA
Type: Predictive Biomarker (PRD)
Genes: AGL; GDE
Study 16048810 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16048810 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 29572094 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 22251436 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 9790083 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9790083 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9790083 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 6764750 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 28481007 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 7933440 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25913417 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20647285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29573355 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15531906 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15531906 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 10990148 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 30651573 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30651573 — Biomarker: Interleukin 6 receptor alpha
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: IL6R
Study 30651573 — Biomarker: IL6ST mRNA
Type: Predictive Biomarker (PRD)
Genes: IL6ST
Study 24090427 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29141087 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2976414 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 24986722 — Biomarker: TNNT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNNT1; TNT
Study 18573823 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8983446 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29696360 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 27583311 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 25924781 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25924781 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22177779 — Biomarker: FGFR1
Type: Predictive Biomarker (PRD)
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 21400196 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16469753 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15531001 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15531001 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1483439 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29982704 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9469496 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 19772447 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 19772447 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17294445 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17294445 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 11158191 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 11158191 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9358196 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3673877 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 29661497 — Biomarker: NDP mRNA
Type: Predictive Biomarker (PRD)
Genes: NDP; EVR2
Study 24846652 — Biomarker: TSLP mRNA
Type: Predictive Biomarker (PRD)
Genes: TSLP
Study 24846652 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 15662232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10549114 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21652583 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 26937774 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 20932189 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 16324343 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16324343 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16324343 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12196338 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26040633 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22485058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19761936 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11448321 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3173455 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31816875 — Biomarker: RELA mRNA
Type: Predictive Biomarker (PRD)
Genes: RELA; NFKB3
Study 31816875 — Biomarker: TNFRSF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1A; TNFAR; TNFR1
Study 28522220 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28522220 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 15089806 — Biomarker: GNB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNB3
Study 15089806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7868672 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 7868672 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 3280220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30649752 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 23485520 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 21515206 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12324912 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27569351 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 24844611 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 14559319 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19717534 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17337164 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 21517955 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21517955 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21517955 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10690445 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3767127 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 3662385 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12443672 — Biomarker: CTBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CTBS; CTB
Study 10442154 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 8546287 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8546287 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 8546287 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8546287 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8546287 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 820703 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 30922964 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 15365065 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 15365065 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11713926 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 18332475 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 12664054 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 28196620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22473163 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 2177746 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15288885 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22006050 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 22006050 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21785963 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 19350340 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17254760 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15284603 — Biomarker: SEMG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEMG1; SEMG
Study 31303390 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31303390 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28381516 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 20008182 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 31594375 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19320235 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 9546962 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 30575683 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25716971 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 25716971 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10989321 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9194510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3929694 — Biomarker: TAOK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 16645424 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 12870137 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 21545397 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11353877 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11353877 — Biomarker: Protein AMBP
Type: Safety Biomarker (SAF)
Genes: AMBP; HCP; ITIL
Study 11353877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18676275 — Biomarker: PRAC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRAC1; C17orf92; PRAC
Study 10685667 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8775698 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 6150000 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30230920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26851191 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 24532078 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 7564363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2197005 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20922438 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16705107 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16705107 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10071280 — Biomarker: HDC mRNA
Type: Predictive Biomarker (PRD)
Genes: HDC
Study 10071280 — Biomarker: AFM mRNA
Type: Predictive Biomarker (PRD)
Genes: AFM; ALB2; ALBA
Study 29361199 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29361199 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 29361199 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29361199 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18316794 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18316794 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 16717170 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 2446057 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30400774 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20569086 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20569086 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18520294 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18520294 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18520294 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 15893182 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31971678 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23681967 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885
Study 23681967 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23659666 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 11271189 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28893900 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16965728 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16965728 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16876495 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8529760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1952145 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27574886 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9068393 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 9068393 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 4009330 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 26194532 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 8739023 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29631362 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 10386179 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 22835668 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 17643772 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 9526937 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7983291 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7983291 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7983291 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7983291 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 29962180 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29962180 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29962180 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29962180 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10527977 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29961920 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 27455318 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27455318 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10612536 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 24285801 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16112972 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16112972 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11770708 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9037443 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2737688 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2737688 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21087377 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7051762 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22728693 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 19846026 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17561998 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 15447895 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15447895 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2643284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9504133 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 31786338 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29450468 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 29450468 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 20305865 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 7776678 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 21613575 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21613575 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 3318724 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 3318724 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24594059 — Biomarker: EMB mRNA
Type: Predictive Biomarker (PRD)
Genes: EMB
Study 12795770 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 12795770 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24848975 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 19521894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15084937 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2442559 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24093858 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 24093858 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21346065 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17263129 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 17263129 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12296610 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25729878 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 23118056 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 19258083 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 17216477 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)