AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 8181800 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8181800 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 30343531 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22717286 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12110062 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30039991 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 30115425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22873530 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17786056 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17786056 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15027165 — Biomarker: SLC4A7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC4A7; BT; NBC2; NBC2B; NBC3; NBCn1; SBC2; SLC4A6
Study 25643028 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 10937952 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10937952 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12450697 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10803488 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10803488 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31709879 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31709879 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 21707766 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 15161789 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 30660196 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 28318997 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27543885 — Biomarker: OXTR mRNA
Type: Predictive Biomarker (PRD)
Genes: OXTR
Study 27543885 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 22913890 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22913890 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17654442 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17654442 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 6118058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9860145 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 9860145 — Biomarker: RAPGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 9860145 — Biomarker: GNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNL3; E2IG3; NS
Study 9860145 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7719388 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2223582 — Biomarker: PRLR mRNA
Type: Predictive Biomarker (PRD)
Genes: PRLR
Study 7368968 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28425827 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 11035676 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 11035676 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 31655598 — Biomarker: OSCAR mRNA
Type: Predictive Biomarker (PRD)
Genes: OSCAR
Study 25883112 — Biomarker: SLC27A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC27A1; ACSVL5; FATP1
Study 18521090 — Biomarker: NPAS3 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: NPAS3; BHLHE12; MOP6; PASD6
Study 18521090 — Biomarker: XK mRNA
Type: Predictive Biomarker (PRD)
Genes: XK; XKR1; XRG1
Study 18521090 — Biomarker: XKR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: XKR4; KIAA1889; XRG4
Study 18521090 — Biomarker: TNR mRNA
Type: Predictive Biomarker (PRD)
Genes: TNR
Study 18521090 — Biomarker: GRIA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIA4; GLUR4
Study 18521090 — Biomarker: GFRA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GFRA2; GDNFRB; RETL2; TRNR2
Study 18521090 — Biomarker: HTR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR7
Study 28972854 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24887223 — Biomarker: S100A12 mRNA
Type: Predictive Biomarker (PRD)
Genes: S100A12
Study 24887223 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27695944 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 7800739 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30977089 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 30977089 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30742692 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 28535933 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 28535933 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 28535933 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23899426 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 31451954 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31451954 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26176708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24810493 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 24810493 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 24810493 — Biomarker: ROS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROS1; MCF3; ROS
Study 24810493 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 24810493 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24810493 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 24810493 — Biomarker: Serine/threonine-protein kinase STK11
Type: Safety Biomarker (SAF)
Genes: STK11
Study 24810493 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 20233513 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 11774064 — Biomarker: Succinate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: SDHD
Study 9519219 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 15126003 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15126003 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31539601 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27722772 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885
Study 27722772 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20598983 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14602746 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30954146 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 9714692 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9714692 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 9714692 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 8313807 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 8313807 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 12702132 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12702132 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 10878501 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22486226 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20427749 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 16095500 — Biomarker: HLA-C
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HLA-JY3, D6S204, PSORS1
Study 12360162 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10366224 — Biomarker: ATXN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATXN1; ATX1; SCA1
Study 10366224 — Biomarker: Ataxin-2
Type: Pharmacodynamic Biomarker (PDY)
Genes: ATXN2; ATX2; SCA2; TNRC13
Study 10366224 — Biomarker: Ataxin-3
Type: Pharmacodynamic Biomarker (PDY)
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 31743809 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14687239 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 14687239 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10899847 — Biomarker: CTBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CTBS; CTB
Study 10899847 — Biomarker: CLSTN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLSTN2; CS2
Study 10899847 — Biomarker: CLSTN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLSTN1; CS1; KIAA0911
Study 8101082 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8101082 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8101082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31550941 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 31550941 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 31550941 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 29097487 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17396066 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17396066 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 7533343 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31558866 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23482466 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study 27928843 — Biomarker: CPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPB1; CPB; PCPB
Study 26433456 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26433456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16434455 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 31694394 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31694394 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27182679 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 27182679 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 27182679 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27182679 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27182679 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27182679 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 7766965 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 7586343 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2408233 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31388104 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 30838448 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22349568 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18084799 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 15585598 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 15585598 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20691834 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 15781499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12519833 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29960287 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29960287 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15156934 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15156934 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 25951232 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 9227927 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 28058750 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 16420077 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 18992951 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 28817248 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 28817248 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24942553 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 24942553 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 24942553 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9171947 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9171947 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 9171947 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 30038154 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 26718419 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 23184657 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 10599773 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 1663965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30998792 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 8097788 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28171220 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 26553684 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 19001327 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28719155 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28719155 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 28719155 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28719155 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 25249568 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18611200 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 27842495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16901645 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 28605608 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11168509 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 28506118 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26564452 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18305385 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29197999 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29197999 — Biomarker: miR-21
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR21
Study 29197999 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22064686 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22064686 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20134098 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10511320 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30717112 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26775474 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 16821420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14571610 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 1578874 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 3905210 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26576711 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 15961004 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29289538 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 29289538 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24957073 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 22236405 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 28068560 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7662240 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11798012 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25827430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23359520 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23359520 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14599854 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7570621 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 20419336 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9193837 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1358003 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2997306 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30887250 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30887250 — Biomarker: NOTCH3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOTCH3
Study 30887250 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31119173 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 25008546 — Biomarker: ADORA2A
Type: Safety Biomarker (SAF)
Genes: RDC8
Study 14722542 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3400079 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 30821829 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21838092 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25966339 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25966339 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22358273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12708976 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10743796 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25243534 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17485593 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 31129907 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 23448618 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 16799034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31174576 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 20950385 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 7677387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31116313 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31116313 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31116313 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11477342 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9667249 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 3289507 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25947167 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 25947167 — Biomarker: BDNF
Type: Safety Biomarker (SAF)