AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 17957097 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17957097 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 17957097 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 15014297 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15014297 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8175136 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 29508247 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 29508247 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 29508247 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29508247 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 2258894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28215131 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 21625270 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 7976152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24034079 — Biomarker: NUBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUBP1; NBP; NBP1
Study 3914582 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 18929475 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11081784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30355325 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30355325 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30355325 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20056736 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 20056736 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10231502 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26947523 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20637969 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17517804 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8551469 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 22091534 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10673876 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 10673876 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23194084 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 14515196 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27733522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27733522 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22782949 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 20075020 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25386713 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15764851 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9648050 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 9648050 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 9648050 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 20545689 — Biomarker: SCN8A mRNA
Type: Predictive Biomarker (PRD)
Genes: SCN8A; MED
Study 12089891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31809479 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 31132105 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 31132105 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 28789492 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 23660206 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10674777 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27769273 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 25315204 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 23053638 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23053638 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23053638 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 15342674 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 7736528 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 30670010 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30670010 — Biomarker: AIP mRNA
Type: Predictive Biomarker (PRD)
Genes: AIP; XAP2
Study 30670010 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30670010 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 30670010 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27193080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25311995 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 23090145 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8800584 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8800584 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31027883 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31027883 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 31027883 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31027883 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31027883 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31027883 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 31027883 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 26947315 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 22348233 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18413426 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 15710045 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 15710045 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11831538 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15148924 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 6337004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24190860 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24190860 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20483364 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 3539030 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 15866552 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 26891677 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19944580 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 19944580 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 18035195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15672116 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 6813126 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17130267 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17130267 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17130267 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 24569045 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 16984938 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16984938 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 16984938 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 16984938 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 31833868 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 17876365 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17876365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7917576 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2780070 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31399446 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11408847 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11408847 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16194620 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 3009726 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 24604243 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 20189654 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 12131561 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12131561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9387637 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 6481116 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18154905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12181386 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27523583 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 24366395 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22484777 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30099113 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study 18309905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29917069 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29917069 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 18845972 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18845972 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7475658 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 27452202 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 27452202 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24666814 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2532946 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 25776840 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 25776840 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 25776840 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 17999779 — Biomarker: SMG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMG1; ATX; KIAA0421; LIP
Study 17999779 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 17999779 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 17999779 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9043725 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 14513039 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 14513039 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 10994909 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 21291422 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 12734156 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19997751 — Biomarker: HGD mRNA
Type: Predictive Biomarker (PRD)
Genes: HGD; HGO
Study 10574653 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8531542 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 30835880 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 30835880 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 14642140 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 14642140 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 10430112 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11095468 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 7722967 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25909710 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25909710 — Biomarker: TNFRSF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1A; TNFAR; TNFR1
Study 25909710 — Biomarker: TNFRSF1B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1B; TNFBR; TNFR2
Study 24781527 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24781527 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 24781527 — Biomarker: EML4 mRNA
Type: Predictive Biomarker (PRD)
Genes: EML4; C2orf2; EMAPL4
Study 24781527 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 24781527 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 22366136 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 22366136 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12576241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12692572 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12692572 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12692572 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10229991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8298199 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22985572 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22985572 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18718422 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 28325697 — Biomarker: Activated leukocyte cell adhesionmolecule
Type: Predictive Biomarker (PRD)
Genes: ALCAM; MEMD
Study 28325697 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 26179090 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 9852695 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25307130 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 18804330 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9190004 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25348346 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 17631702 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30509850 — Biomarker: Platelet-derived growth factor B
Type: Pharmacodynamic Biomarker (PDY)
Genes: PDGFB; PDGF2; SIS
Study 29316154 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27590259 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 27590259 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23238658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21317434 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19966913 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23369948 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 23369948 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11688002 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7955182 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 23204039 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23204039 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19729522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16974199 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15339684 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study 15339684 — Biomarker: FTL mRNA
Type: Predictive Biomarker (PRD)
Genes: FTL
Study 15339684 — Biomarker: ZNF423 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZNF423; KIAA0760; NPHP14; OAZ
Study 31549519 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 21930719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21179729 — Biomarker: STAT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT4
Study 31724891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30131256 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30131256 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20438786 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 20438786 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20438786 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 391257 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 23942329 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 23942329 — Biomarker: LMO2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LMO2; RBTN2; RBTNL1; RHOM2; TTG2
Study 25449224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23545347 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23545347 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23545347 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 23545347 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 15265255 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2965159 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 2965159 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24232638 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24232638 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23281842 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 9285181 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9285181 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 23003342 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 15931642 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15931642 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 20802298 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17651830 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15774607 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)