AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 8649628 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8649628 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28700781 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 28700781 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22045829 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17290158 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15625409 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24356937 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17469099 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 29063827 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23751521 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9660035 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23525448 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 16873594 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7669959 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17295604 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17295604 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 11504286 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9467533 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 9467533 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 29473354 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29473354 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26816234 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19952712 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19952712 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8917026 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8917026 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8917026 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 2784824 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 27136906 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25924029 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 24091311 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21623467 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27939836 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 24335969 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15457277 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15457277 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24044803 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 17396057 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17396057 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17396057 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 27765756 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 23063263 — Biomarker: ELK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELK3; NET; SAP2
Study 15691342 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 12534402 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30589533 — Biomarker: TPH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH2; NTPH
Study 30589533 — Biomarker: HTR1A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR1A; ADRB2RL1; ADRBRL1
Study 30589533 — Biomarker: HTR1B mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR1B; HTR1DB
Study 30589533 — Biomarker: HTR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2A; HTR2
Study 30589533 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 30241302 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 26621909 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24445737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19410576 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 19410576 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 15522363 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 22161999 — Biomarker: FMN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMN1; FMN; LD
Study 22161999 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 11746320 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31613424 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 21718908 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16831828 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14612286 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 7726672 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 7726672 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31600487 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31600487 — Biomarker: HLA-DQA1
Type: Safety Biomarker (SAF)
Genes: CELIAC1
Study 30209855 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 25990414 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9146848 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 30458805 — Biomarker: CTSC mRNA
Type: Predictive Biomarker (PRD)
Genes: CTSC; CPPI
Study 23916045 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 12850963 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29952487 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 15919489 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 26878838 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 19783324 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15621801 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 28304224 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 28304224 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23880306 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21714857 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 21714857 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 19379152 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11263600 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 11263600 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9135945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26689566 — Biomarker: Aurora kinase A
Type: Predictive Biomarker (PRD)
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 16163920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27894336 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27894336 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23891072 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21192262 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 7679166 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7679166 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24643905 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19941679 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 12660934 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12660934 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 30650445 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30650445 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 30650445 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30650445 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23882146 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23882146 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15899959 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9718588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8573552 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16448890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15065530 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 24861959 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21491121 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 15224086 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 9530643 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9530643 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26256065 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23146744 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15073471 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15073471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30710211 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30710211 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21649817 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 3098 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29216250 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 29216250 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 26140943 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 26140943 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23268367 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 23268367 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23268367 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20961333 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 20961333 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24850280 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 15820814 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 12212781 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8564348 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 10516515 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6309542 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29274618 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 20489741 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 20489741 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 15750042 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 15750042 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 10499226 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 8544280 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30785379 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21422768 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 21422768 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 15163474 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15163474 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11339401 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 9159306 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9159306 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31711513 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 27702823 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 23802920 — Biomarker: TBC1D4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TBC1D4; AS160; KIAA0603
Study 21783046 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16306998 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9463204 — Biomarker: SLC12A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC12A3; NCC; TSC
Study 3486551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17225518 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15513312 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 2478778 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29093005 — Biomarker: Macrophage inflammatory protein 1-alpha
Type: Monitoring Biomarker (MOI)
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 18192906 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12704306 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 12704306 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 9364618 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 3890394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27029487 — Biomarker: Mitochondrial frataxin
Type: Monitoring Biomarker (MOI)
Genes: FXN; FRDA; X25
Study 10857839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1615175 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24854306 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12970006 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 31124918 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31277561 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31277561 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23519546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23519546 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21660636 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 21660636 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21660636 — Biomarker: Angiopoietin-1
Type: Monitoring Biomarker (MOI)
Genes: ANGPT1; KIAA0003
Study 19172849 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 27122080 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 27122080 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 21787454 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19031218 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19031218 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10027319 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27108936 — Biomarker: SHD mRNA
Type: Predictive Biomarker (PRD)
Genes: SHD
Study 20962315 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20962315 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16258083 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9798136 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9798136 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31147675 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 31147675 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 31147675 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 16721396 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8355037 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25711955 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 23107605 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 17388006 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17388006 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10774248 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 12390335 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26418205 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 20838058 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 10804484 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22306844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9536505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19367322 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 15042116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7866680 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27937096 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 27937096 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 26664397 — Biomarker: SNAP25 mRNA
Type: Predictive Biomarker (PRD)
Genes: SNAP25; SNAP
Study 60566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31749051 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 7954529 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31943168 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23532888 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 18826858 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 18826858 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 17121038 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 27555998 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study 24814857 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 10998029 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8868605 — Biomarker: ESD mRNA
Type: Predictive Biomarker (PRD)
Genes: ESD
Study 2442536 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29807824 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 19941694 — Biomarker: FGA mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGA
Study 18272475 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 26785372 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 18192850 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18192850 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB