AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 28837504 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25319385 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 31124042 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1396624 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27428192 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27428192 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31553834 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28915826 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26086941 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 26086941 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8459971 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8459971 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30225268 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26795100 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 19539141 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 2104627 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 2104627 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31277886 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 26071592 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11020745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21242364 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8112370 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 8112370 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8112370 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 30048473 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30048473 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12369652 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 12369652 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26418022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17088770 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 10997402 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28441294 — Biomarker: SIRPA mRNA
Type: Predictive Biomarker (PRD)
Genes: SIRPA; BIT; MFR; MYD1; PTPNS1; SHPS1; SIRP
Study 21396214 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21396214 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21396214 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18510607 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8971427 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8971427 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30318561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21287409 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25409877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23585522 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 3498395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29314455 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23898483 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23898483 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 23898483 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20204604 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7948800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2451883 — Biomarker: PIK3AP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3AP1; BCAP
Study 26253933 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 26253933 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 26253933 — Biomarker: TICAM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TICAM1; PRVTIRB; TRIF
Study 26253933 — Biomarker: TLR2
Type: Predictive Biomarker (PRD)
Genes: TIL4; CD282
Study 26253933 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21247733 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12928941 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12928941 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 21898340 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 9040450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9040450 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 9040450 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22008690 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22008690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14533665 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 9635271 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25348000 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25348000 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25348000 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 25348000 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 19741509 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 3116982 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 25351788 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 2975290 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2975290 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24331681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6729769 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 29228205 — Biomarker: PGR mRNA
Type: Predictive Biomarker (PRD)
Genes: PGR; NR3C3
Study 29228205 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29228205 — Biomarker: ESR2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ESR2; ESTRB; NR3A2
Study 29228205 — Biomarker: CYP17A1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CYP17A1; CYP17; S17AH
Study 29228205 — Biomarker: HSD17B1 mRNA
Type: Safety Biomarker (SAF)
Genes: HSD17B1; E17KSR; EDH17B1; EDH17B2; EDHB17; SDR28C1
Study 29228205 — Biomarker: CYP19A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 29228205 — Biomarker: CYP1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A1
Study 29228205 — Biomarker: CYP1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1B1
Study 29228205 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 29228205 — Biomarker: UGT2B7 mRNA
Type: Predictive Biomarker (PRD)
Genes: UGT2B7; UGTB2B9
Study 29228205 — Biomarker: UGT2B15 mRNA
Type: Predictive Biomarker (PRD)
Genes: UGT2B15; UGT2B8
Study 17913669 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 10396719 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 29880794 — Biomarker: ID1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ID1; BHLHB24; ID
Study 25196041 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 21896498 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12516653 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 12516653 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31105703 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31105703 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27853886 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21762532 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 15302008 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 29483583 — Biomarker: ETV6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV6; TEL; TEL1
Study 8139085 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8139085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8139085 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23517506 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 16778364 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8512601 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8512601 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26561294 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26561294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19309495 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 30912285 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 30912285 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 29049251 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20329604 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 408607 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 3511693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3511693 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3511693 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26690310 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26690310 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 22065400 — Biomarker: SKI mRNA
Type: Predictive Biomarker (PRD)
Genes: SKI
Study 22065400 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 16020405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7832332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24839144 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 24839144 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 24839144 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20590588 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 20590588 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 15795705 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7807033 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1778219 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 1778219 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 1778219 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 6168121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25985241 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 25985241 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25985241 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17929538 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 31250043 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18632657 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 16212580 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 11513771 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 30571543 — Biomarker: NE
Type: Predictive Biomarker (PRD)
Study 30571543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27863845 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 15100679 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 27282755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16872952 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 10657867 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 3524588 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 28914726 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17287908 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12139543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9459316 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 9459316 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 9459316 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 7657419 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20580618 — Biomarker: GAD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD2; GAD65
Study 10199877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29374510 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 15792016 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 11574441 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 8800732 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21088211 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16903595 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 2892143 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26783268 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 9007178 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 25225436 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 25225436 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7714086 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2692963 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2692963 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11358646 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3261158 — Biomarker: RASL12 mRNA
Type: Predictive Biomarker (PRD)
Genes: RASL12; RIS
Study 26456372 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21505506 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21505506 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17664851 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22811306 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22811306 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 22811306 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22811306 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2288828 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16965635 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11232497 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 30795958 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 28847886 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26346302 — Biomarker: FADS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS1; FADSD5
Study 19770624 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19770624 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19770624 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23512743 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14508127 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 22527222 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 2766661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20185560 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6274471 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 6274471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22732511 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7805235 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7250172 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7250172 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 15025612 — Biomarker: SPIN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SPIN1; OCR; SPIN
Study 9267946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8305657 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 20298924 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16422888 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12829908 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 30407312 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30407312 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 26610643 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 24253758 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 22124880 — Biomarker: SLCO1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 22124880 — Biomarker: SLCO2B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 31977567 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 31894027 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21420053 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10848875 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20637971 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 11952447 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2650941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2650941 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 368306 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21792215 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15580149 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12001978 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 3228817 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24725308 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22960196 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 16250568 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 16250568 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 12404673 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 21505304 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 21505304 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21505304 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10862159 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24708818 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 24708818 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22607767 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 20518615 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 18571083 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)