AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 15342284 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9603290 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29384722 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18785409 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9625104 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 21606213 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 27992435 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 22538805 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 15630195 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 3120587 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3120587 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3120587 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 31671938 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 21859323 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21859323 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17389710 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17389710 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6259250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15489491 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 30508196 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 28478132 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 16697494 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16697494 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 15477632 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 15477632 — Biomarker: DHFR
Type: Safety Biomarker (SAF)
Genes: DHFR1
Study 8970755 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8970755 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28089476 — Biomarker: RANGAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RANGAP1; KIAA1835; SD
Study 28089476 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 26149722 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19789402 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19789402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26712786 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23426035 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1637794 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31058977 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31058977 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 20160750 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 18839781 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11500190 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 1332102 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8788535 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 26363985 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26363985 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19922882 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14993020 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 26888146 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 11127936 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11127936 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31500670 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 28195952 — Biomarker: CYBC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYBC1; C17orf62; EROS
Study 16817913 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 30160521 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 30160521 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12886816 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30085292 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27712772 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20228404 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10937983 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6753891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31049877 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31049877 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25644340 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17195531 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29547834 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11783143 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11783143 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 11783143 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11783143 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 11783143 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11783143 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11783143 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11783143 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 11783143 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7762505 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 7762505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12169045 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 2180267 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2180267 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7813389 — Biomarker: L-acetylcarnitine
Type: Safety Biomarker (SAF)
Study 24166906 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24166906 — Biomarker: Fibroblast growth factor 1
Type: Safety Biomarker (SAF)
Genes: FGF1
Study 15356084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15356084 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15356084 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 11458055 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 2977273 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 8156307 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31185942 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31185942 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 29249140 — Biomarker: SCARA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SCARA3; CSR
Study 29249140 — Biomarker: GAL3ST1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAL3ST1; CST
Study 20154074 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 20154074 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 20154074 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20154074 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31623760 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 12011785 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 2527544 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2527544 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31197361 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 28087178 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 14755979 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10727313 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2933999 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2933999 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31053142 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17387332 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 17387332 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 12830340 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11273913 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8510388 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 27496229 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 27496229 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 27496229 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21200437 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17526320 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16003289 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 12462291 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12462291 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 31376708 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 26061572 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 24343322 — Biomarker: LSAMP mRNA
Type: Predictive Biomarker (PRD)
Genes: LSAMP; IGLON3; LAMP
Study 2475701 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21883902 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 11240234 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9469326 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 1967227 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1967227 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31286931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29066863 — Biomarker: Nqo1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: NQO1; DIA4; NMOR1
Study 15302727 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 9493664 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2502583 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 2502583 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 7857363 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 7857363 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 7857363 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31044290 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 28727817 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25437881 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26595801 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 15465740 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 20667937 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20667937 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 12897033 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 3079687 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 22077482 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 20427397 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 16258776 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 12384804 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7624601 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2655611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30850240 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30850240 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 3567042 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27558788 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 8914118 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31812956 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19105915 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19105915 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19105915 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7830631 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7830631 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2575981 — Biomarker: MAVS mRNA
Type: Predictive Biomarker (PRD)
Genes: MAVS; IPS1; KIAA1271; VISA
Study 25689244 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 6430439 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 31099333 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31099333 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31099333 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31099333 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 24436297 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12111109 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9892304 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30586738 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28063245 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 28063245 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 21169640 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17598009 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 17598009 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15373928 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 2959426 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20670726 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11813764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28619701 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 15621710 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 28903510 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 28903510 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 21240871 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21240871 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 16505413 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 8891847 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 1381022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6383655 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 6383655 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31126299 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 31126299 — Biomarker: IRX3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRX3; IRXB1
Study 21199966 — Biomarker: LTB4R mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 29763623 — Biomarker: POLE mRNA
Type: Predictive Biomarker (PRD)
Genes: POLE; POLE1
Study 29763623 — Biomarker: POLD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: POLD1; POLD
Study 29763623 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study 9124243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19328598 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 16827430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16827430 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 12662378 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 10511770 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10511770 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study 10511770 — Biomarker: ANTXR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANTXR1; ATR; TEM8
Study 10511770 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 7556745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25741580 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 23446957 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10765078 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9206199 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24290850 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 7910230 — Biomarker: TAOK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 31959416 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31959416 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29369834 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 10489003 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 1767541 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 20415574 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2111239 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6653648 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7621766 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 28361235 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 23910207 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 21764705 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 21764705 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23480528 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 21181138 — Biomarker: DRD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD1
Study 21181138 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 18584240 — Biomarker: PAG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAG1; CBP; PAG
Study 2414590 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8461542 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2945717 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18485132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12774138 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28419368 — Biomarker: LTA4H mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA4H; LTA4
Study 16597076 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 16597076 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27252432 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 20687400 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 8656661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1801883 — Biomarker: TAC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAC1; NKA; NKNA; TAC2
Study 29142926 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 21315219 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)