AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31387158 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20425851 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 29042392 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 29042392 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 23427930 — Biomarker: PGP mRNA
Type: Predictive Biomarker (PRD)
Genes: PGP
Study 19797187 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16825271 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12868253 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 31424665 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 31424665 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 31424665 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 31424665 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 31424665 — Biomarker: ICOS mRNA
Type: Predictive Biomarker (PRD)
Genes: ICOS; AILIM
Study 28004259 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 26697176 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 23452432 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 16537662 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23919274 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 12113544 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12113544 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29653652 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 22464802 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11879528 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11879528 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8652236 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24389453 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22968159 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 17439382 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17439382 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9987143 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 29030343 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15088136 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11427834 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22613524 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22613524 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8370856 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 29432644 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 10709886 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1828183 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 1828183 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 6758745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25765144 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26608978 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23142439 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17142523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17142523 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11049894 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30111216 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30111216 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30111216 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22491538 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11086 — Biomarker: N-acetylneuraminic acid
Type: Safety Biomarker (SAF)
Study 11086 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27203734 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 25371035 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 29547234 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16042894 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 1883793 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 21443612 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 17003366 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 16506860 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10946879 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 6388586 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24474180 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24474180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22350323 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20308670 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17296641 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 30252061 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9843529 — Biomarker: Heat shock 70 kDa
Type: Safety Biomarker (SAF)
Study 31028614 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 24491880 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24491880 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 24491880 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19905945 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 31014369 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 2600748 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 15619966 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 11204294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11950706 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 7628885 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2487802 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31629805 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 31629805 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 31629805 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 31629805 — Biomarker: JAK2
Type: Predictive Biomarker (PRD)
Genes: JTK10
Study 27301456 — Biomarker: PLA2G7 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G7; PAFAH
Study 25516316 — Biomarker: Amyloid beta peptide (1-40)
Type: Pharmacodynamic Biomarker (PDY)
Genes: APP; A4; AD1
Study 25516316 — Biomarker: PSEN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PSEN1; AD3; PS1; PSNL1
Study 25516316 — Biomarker: TFF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TFF1; BCEI; PS2
Study 22883034 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 18362932 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18362932 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10923280 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10923280 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8638517 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 8638517 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31254596 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 26750378 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20838372 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17949392 — Biomarker: GABRA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GABRA2
Study 31480637 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 31480637 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31480637 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31480637 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29568003 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23192897 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 22842368 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22842368 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22842368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20566009 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7930718 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 31142294 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21298840 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30860573 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 30860573 — Biomarker: STUB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STUB1; CHIP; PP1131
Study 24408035 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17253178 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28079600 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 18287807 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 18287807 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 8836914 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1562097 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3933677 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 24739538 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29080386 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 29080386 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 27869287 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27869287 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27434393 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 27434393 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 17689627 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9650737 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8077800 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31934946 — Biomarker: BTG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BTG2; PC3
Study 31934946 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 17092978 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15158296 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 10439887 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23393104 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23393104 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 17824470 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17824470 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24150249 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11441903 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19303015 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15243278 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11061584 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 11061584 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 22605788 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22605788 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22605788 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19758440 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19758440 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19758440 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19758440 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24530156 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31574794 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31574794 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24995515 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 21078951 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28329919 — Biomarker: BTC mRNA
Type: Predictive Biomarker (PRD)
Genes: BTC
Study 26244978 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 24257178 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 1447105 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 1447105 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25688059 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25688059 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29508689 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 1828348 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 1828348 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29470317 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29470317 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 29470317 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19478215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10624641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8745137 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 31216321 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22169051 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18175518 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 12410054 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12410054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10218748 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29733225 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31999297 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22539379 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 22539379 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8739811 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 1831059 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 6642790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26702120 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22574737 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 22574737 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 11444420 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28697767 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28697767 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28697767 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19762739 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 19762739 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19762739 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 19762739 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 19762739 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 19762739 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 19762739 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17174222 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15185314 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9664985 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 26083005 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 15362963 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19349544 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 16775558 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 21037100 — Biomarker: C-C motif chemokine 19
Type: Safety Biomarker (SAF)
Genes: CCL19; ELC; MIP3B; SCYA19
Study 21037100 — Biomarker: CCL21 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL21; SCYA21; UNQ784/PRO1600
Study 21037100 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 9381994 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 30509713 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30509713 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20349155 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31067674 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31067674 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10792330 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2780087 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22578254 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 1888800 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 22113064 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22113064 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22113064 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22113064 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12794818 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10520056 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19892499 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10051289 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7670117 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study 1688039 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21991949 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31296256 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 31296256 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21146229 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 10890611 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 21573819 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 17307426 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9356783 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31762471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)