AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 28606441 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 28606441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15697056 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 12017347 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15526237 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15526237 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22436400 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16162943 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12578865 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12578865 — Biomarker: ADIPOQ mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 10319771 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 10319771 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31816446 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 31816446 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9135928 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29970059 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 24041914 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 11899644 — Biomarker: HDC mRNA
Type: Predictive Biomarker (PRD)
Genes: HDC
Study 26827702 — Biomarker: PENK mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PENK
Study 22527351 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 22527351 — Biomarker: UGT2B7 mRNA
Type: Predictive Biomarker (PRD)
Genes: UGT2B7; UGTB2B9
Study 17684125 — Biomarker: AMACR mRNA
Type: Predictive Biomarker (PRD)
Genes: AMACR
Study 28092973 — Biomarker: ADAMTS7 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAMTS7
Study 9486993 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9486993 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2244564 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20298505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25925891 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 8147246 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 26880227 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20501489 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20501489 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 30762770 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 30762770 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 30762770 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28152332 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 15283821 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11207468 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15448121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9884318 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 24229754 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 14748768 — Biomarker: ACSL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACSL1; FACL1; FACL2; LACS; LACS1; LACS2
Study 2865889 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23149426 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3839174 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 24712573 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 2955979 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22418044 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 22418044 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25778333 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 9331924 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 19595257 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 3579004 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 26717214 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10750574 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31119206 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2757896 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14971964 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 11346705 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11346705 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 9040797 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 7931444 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23945719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18299490 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 2972159 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 25823909 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10658682 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 10658682 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 2126727 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25927716 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 14718679 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 11433128 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11433128 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 11433128 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9773138 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 19483278 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 19287303 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11165950 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9708956 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 8069001 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 30736402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21321298 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 7512659 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 31983236 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31983236 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 31291514 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25861013 — Biomarker: TBC1D4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TBC1D4; AS160; KIAA0603
Study 25861013 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 21461325 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 11121913 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 3519237 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8712196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30239650 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 30239650 — Biomarker: CCR2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCR2; CMKBR2
Study 22264573 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1691243 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28797349 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 28797349 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24119112 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19497571 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19497571 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12359793 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 12359793 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9695133 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 873718 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2700320 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17607002 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 17607002 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7884789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11465928 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 11465928 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9715439 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2646896 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19756505 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 7589042 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25796973 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 25796973 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 23815518 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23815518 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21837954 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 11264569 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 7839785 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27296202 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 10396191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7027889 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27786406 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 17003087 — Biomarker: GHR mRNA
Type: Predictive Biomarker (PRD)
Genes: GHR
Study 17003087 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 9375939 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9375939 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26962236 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26962236 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 26962236 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 6639917 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31541874 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31541874 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11279634 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11279634 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 2540054 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2540054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 989578 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 30192802 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 30192802 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 30192802 — Biomarker: T-cell specific protein RANTES
Type: Safety Biomarker (SAF)
Genes: CCL5; D17S136E; SCYA5
Study 30192802 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 30192802 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 20398482 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15880810 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 11689270 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28124536 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 19214143 — Biomarker: ABCC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC1; MRP; MRP1
Study 19214143 — Biomarker: ALOX5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALOX5; LOG5
Study 19214143 — Biomarker: CYSLTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYSLTR1; CYSLT1
Study 19214143 — Biomarker: LTA4H mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA4H; LTA4
Study 17264955 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 11409217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9493975 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 15361745 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 2955717 — Biomarker: ANTXR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANTXR1; ATR; TEM8
Study 2955717 — Biomarker: SDC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SDC1; SDC
Study 25861808 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 22326387 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 2184938 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2184938 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31589776 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28390867 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1412152 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 1412152 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 23725092 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19959915 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15356403 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11438314 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11438314 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11438314 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 28651648 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 28651648 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23399476 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 14731120 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 11477496 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 31334703 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31334703 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25666295 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 25666295 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 21857944 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21857944 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21857944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19039620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26330412 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26330412 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8824693 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8824693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30964824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20949133 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20949133 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 20949133 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 20949133 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 20949133 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16263208 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 29107562 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19188504 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 23211335 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 23211335 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 19456248 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19456248 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12482562 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 12482562 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 12482562 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3298387 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 29193662 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30944029 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30944029 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 22298600 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27255456 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15958836 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7674270 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29154056 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29154056 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23611083 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21936251 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21936251 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29318860 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21817116 — Biomarker: BBC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BBC3; PUMA
Study 21817116 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 14976885 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 25524543 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21360924 — Biomarker: SERPINF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINF2; AAP; PLI
Study 16281491 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10464060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2210987 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2210987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2210987 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 26683599 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 18410584 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15838561 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15838561 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12000008 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12000008 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 12000008 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 12000008 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8670316 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8670316 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1