AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31126960 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26442399 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3792081 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 3792081 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28507187 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26778524 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23158914 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16205916 — Biomarker: LARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LARS1; KIAA1352; LARS
Study 30128710 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 24216088 — Biomarker: DDC mRNA
Type: Predictive Biomarker (PRD)
Genes: DDC; AADC
Study 22348456 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22348456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20662070 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 7082501 — Biomarker: FGFR1
Type: Predictive Biomarker (PRD)
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 7082501 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18313350 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 16492072 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27546095 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 23009189 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 18319361 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18319361 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15121562 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26349936 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 22782948 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 22782948 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 22782948 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 17924894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9450712 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25713485 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 25713485 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 23410871 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23410871 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 3429863 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26058036 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26058036 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21094804 — Biomarker: CD52 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD52; CDW52; HE5
Study 16837434 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 16837434 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21176784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19237404 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15545308 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 514499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6414060 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 20200548 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15561050 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15561050 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15561050 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 15561050 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15561050 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 27184779 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22851734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22851734 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 11680727 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23897066 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11778950 — Biomarker: ALAD mRNA
Type: Predictive Biomarker (PRD)
Genes: ALAD
Study 21271232 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 11497192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10342793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30739130 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30739130 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30739130 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 30739130 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 21170684 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 21170684 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 21170684 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21170684 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 12843690 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12843690 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12843690 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 12843690 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12843690 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9058443 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 25402332 — Biomarker: CXCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR1; CMKAR1; IL8RA
Study 18555997 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 12556649 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30172703 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 10647267 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1659437 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31593582 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 29326577 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 29326577 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29326577 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 14671247 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1568727 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1568727 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21428467 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 6497936 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25795947 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25795947 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16397167 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 16397167 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 14534519 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 10591840 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 345380 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17893252 — Biomarker: GAL3ST1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAL3ST1; CST
Study 15717651 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 15717651 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 25582305 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 8512761 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18515735 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8185690 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8185690 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25886031 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21365126 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9682339 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 25963237 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11170993 — Biomarker: SLPI mRNA
Type: Predictive Biomarker (PRD)
Genes: SLPI; WAP4; WFDC4
Study 8847042 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 21087072 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18679152 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31444404 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 31444404 — Biomarker: C-X-C motif chemokine 11
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 31444404 — Biomarker: CCL20 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL20; LARC; MIP3A; SCYA20
Study 20881341 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 19020142 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 12895219 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10695778 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29543887 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8915932 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 31684759 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 31684759 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 25074387 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 11942864 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2657276 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 29370333 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29370333 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25939484 — Biomarker: miR-22
Type: Safety Biomarker (SAF)
Genes: MIR22
Study 22343798 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 10086532 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 8748680 — Biomarker: Ataxin-3
Type: Pharmacodynamic Biomarker (PDY)
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 8748680 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 31566129 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 31566129 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 30585454 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30585454 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 15870631 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 11833753 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11833753 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29915021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23774314 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18781872 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12401122 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31395900 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 31395900 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 31395900 — Biomarker: ABCC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC1; MRP; MRP1
Study 31395900 — Biomarker: MRP2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ABCC2; DJS; cMRP
Study 19363973 — Biomarker: ELK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELK3; NET; SAP2
Study 30188231 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 23712757 — Biomarker: SLCO1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 20810374 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 20810374 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 16820345 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26031828 — Biomarker: GATM mRNA
Type: Predictive Biomarker (PRD)
Genes: GATM; AGAT
Study 26031828 — Biomarker: GAMT mRNA
Type: Predictive Biomarker (PRD)
Genes: GAMT
Study 19555253 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19555253 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15390343 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 11228295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2544829 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 21986208 — Biomarker: PTN mRNA
Type: Predictive Biomarker (PRD)
Genes: PTN; HBNF1; NEGF1
Study 9198048 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 30006299 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 27423055 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24332139 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12212977 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 7794850 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29296811 — Biomarker: ADORA2A
Type: Safety Biomarker (SAF)
Genes: RDC8
Study 30348113 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 20338560 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20338560 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 15866563 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1781563 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30727929 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8299664 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8299664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2436183 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 11235004 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 11235004 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 6529523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26993628 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 25276983 — Biomarker: AQP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP4
Study 17509068 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2720192 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 27267614 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 19552750 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16963348 — Biomarker: MNT mRNA
Type: Predictive Biomarker (PRD)
Genes: MNT; BHLHD3; ROX
Study 12359281 — Biomarker: CPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPZ
Study 335490 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31278094 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 31278094 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 31278094 — Biomarker: Cyclin-dependent kinase inhibitor 1
Type: Safety Biomarker (SAF)
Genes: CDKN1A
Study 31278094 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31278094 — Biomarker: TNF-related weak inducer of apoptosis
Type: Predictive Biomarker (PRD)
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study 31278094 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 11491417 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21859685 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 21859685 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11193130 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8473466 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 29776559 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26853286 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 24851690 — Biomarker: GGN mRNA
Type: Predictive Biomarker (PRD)
Genes: GGN
Study 24851690 — Biomarker: MIA mRNA
Type: Predictive Biomarker (PRD)
Genes: MIA
Study 20015788 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10435729 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10435729 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 2132424 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29036816 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 29036816 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 26125443 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20854436 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20854436 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 24691094 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 24691094 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20647575 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7759442 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11305510 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 9772056 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 29912425 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 18043999 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8970917 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30661439 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17377212 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11302565 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 21040375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16317124 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 18263663 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 12483414 — Biomarker: Major prion protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRNP; ALTPRP; PRIP; PRP
Study 10957749 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28606219 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26206258 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24002795 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24002795 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8732473 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28166785 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21355003 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15598915 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19587607 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15630183 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0