AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 20380656 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 31374049 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 25458464 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 23620932 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 16820564 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10828475 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8196571 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30993313 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9864835 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2197536 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24042256 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 19848195 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19848195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19848195 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12165594 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31485929 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 30587521 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2153193 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 29253068 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26484952 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15914936 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 15914936 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8778155 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 8778155 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 1330386 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29071875 — Biomarker: SEPTIN6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEPTIN6; KIAA0128; SEP2; SEPT6
Study 29071875 — Biomarker: SEPTIN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEPTIN3; SEP3; SEPT3
Study 21521341 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 18773374 — Biomarker: F10 mRNA
Type: Predictive Biomarker (PRD)
Genes: F10
Study 18773374 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 18773374 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 10928254 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12148181 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 3353893 — Biomarker: LTB mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB; TNFC; TNFSF3
Study 31227535 — Biomarker: TLR2
Type: Predictive Biomarker (PRD)
Genes: TIL4; CD282
Study 19616494 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19616494 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14991243 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 23744766 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 23744766 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 9192511 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15231982 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11807721 — Biomarker: DHFR mRNA
Type: Predictive Biomarker (PRD)
Genes: DHFR
Study 11807721 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 11807721 — Biomarker: DHFR
Type: Safety Biomarker (SAF)
Genes: DHFR1
Study 25849853 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25849853 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25849853 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21546089 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21546089 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28291675 — Biomarker: CPD mRNA
Type: Predictive Biomarker (PRD)
Genes: CPD
Study 18708687 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18708687 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 16443353 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 1831005 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24216182 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 11103296 — Biomarker: MTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 27181507 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 12646342 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12646342 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19040016 — Biomarker: LAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LAT
Study 12679767 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12679767 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12679767 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 12679767 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29447199 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 2181769 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 383033 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 383033 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28939642 — Biomarker: LIPC mRNA
Type: Predictive Biomarker (PRD)
Genes: LIPC; HTGL
Study 28939642 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 28939642 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23571650 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23571650 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23571650 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 19454869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29923427 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26851146 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 26851146 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31570733 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31570733 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 23645099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17257991 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17257991 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 17257991 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17257991 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 17257991 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 17257991 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 26653189 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 11326179 — Biomarker: DDR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 11326179 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 30678863 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27043452 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 2144154 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23615650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17130197 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 12601628 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 7074797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26419215 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21554817 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14714091 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 14714091 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 2826067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27710149 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 27710149 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 16376979 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7605361 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2357777 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 22283635 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19019257 — Biomarker: ABCG5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG5
Study 19019257 — Biomarker: ABCG8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG8
Study 16405839 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16405839 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16405839 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12021824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2080308 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 30590857 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study 17255371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15371667 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18278183 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26486704 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16529046 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 11768726 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31506877 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31506877 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29231549 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23549132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18505968 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18505968 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 17160915 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17160915 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24401754 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9527749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2673080 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28698476 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 24105072 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 3283766 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 3283766 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 26858013 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 23327968 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10632776 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 27026311 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 23825002 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23825002 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16139580 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 23326865 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2903191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21112101 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 19531453 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 23878368 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23878368 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20808146 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 26892991 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 12756402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27221806 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 24299915 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20812339 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20812339 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 20812339 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7581055 — Biomarker: MEFV mRNA
Type: Predictive Biomarker (PRD)
Genes: MEFV; MEF; TRIM20
Study 10651841 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22211699 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 3332575 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26305413 — Biomarker: NPW mRNA
Type: Predictive Biomarker (PRD)
Genes: NPW; PPL8; PPNPW
Study 22051697 — Biomarker: CRTAM mRNA
Type: Predictive Biomarker (PRD)
Genes: CRTAM
Study 10102158 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 24734908 — Biomarker: PTGDR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 15001199 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3298936 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 27848149 — Biomarker: CA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA1
Study 21516302 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21516302 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 10757623 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28323043 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23107894 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23107894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19295224 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 11792769 — Biomarker: ST3GAL4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ST3GAL4; CGS23; NANTA3; SIAT4C; STZ
Study 11792769 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7594424 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7594424 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 1724914 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 29523624 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20813689 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20813689 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 15144909 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15144909 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2883952 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 29731444 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29731444 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16236684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12837043 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12837043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9694052 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9694052 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9694052 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9694052 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8081529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4552591 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28968163 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28968163 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28968163 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 10449888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30956267 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24010992 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18257347 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18257347 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18257347 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30095354 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 30095354 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 17438101 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 17438101 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17438101 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17438101 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 17438101 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 17438101 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17438101 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 2843341 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2843341 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31635497 — Biomarker: SERPING1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPING1; C1IN; C1NH
Study 23291612 — Biomarker: SHH mRNA
Type: Predictive Biomarker (PRD)
Genes: SHH
Study 23291612 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 23291612 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23291612 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 9082864 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16403712 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309