AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 1395074 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30598484 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24942540 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31150799 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30177026 — Biomarker: TCF7L2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCF7L2; TCF4
Study 25424924 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 25424924 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23163141 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23163141 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15583361 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10743482 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17686445 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17686445 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 17686445 — Biomarker: Ribonucleoside-diphosphate reductase large subunit
Type: Predictive Biomarker (PRD)
Genes: RRM1; RR1
Study 17686445 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 17686445 — Biomarker: XRCC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: XRCC3
Study 15848611 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 15848611 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28589217 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9062473 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7691256 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26315844 — Biomarker: PNPLA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PNPLA3; ADPN; C22orf20
Study 15956998 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28566591 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28566591 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 28566591 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 25118156 — Biomarker: FST mRNA
Type: Predictive Biomarker (PRD)
Genes: FST
Study 15129422 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 15129422 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 9515532 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9515532 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 9515532 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 3123117 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25658881 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11078261 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 10643696 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 29045255 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20210909 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29770393 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 27127346 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 22409423 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 17503687 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 28636184 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 28636184 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16818923 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16818923 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16818923 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7524696 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 3555589 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18187995 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7794582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28276596 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26378683 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9287228 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31413164 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 8682010 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2096405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26385957 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 29057795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19375884 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 16283320 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16283320 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18036453 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17287847 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12031372 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8810174 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31461577 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26398704 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21108431 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 18202666 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18202666 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18202666 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8862238 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26472682 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 26472682 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26472682 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 23747790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23628132 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21342321 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 19644396 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9205939 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9205939 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9205939 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16305600 — Biomarker: ATP1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATP1A1
Study 2194987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21999413 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15075512 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9007492 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8373274 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3115153 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19064024 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9100553 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9100553 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 27376698 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 1936474 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11465967 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8424297 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30120404 — Biomarker: FADS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS1; FADSD5
Study 27621162 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25640891 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19082800 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 8600180 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 8600180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29516305 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 22461242 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22461242 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 20578383 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 21262918 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 7816008 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 7816008 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25413485 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 25413485 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29632222 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23742030 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7594445 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7004250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10719296 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10719296 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 10719296 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 10719296 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 3893106 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27266340 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10406816 — Biomarker: GNAS mRNA
Type: Predictive Biomarker (PRD)
Genes: GNAS; GNAS1
Study 8884862 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 30659024 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 30659024 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 26444853 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 11467638 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 10710067 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16492297 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 16492297 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 10856869 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 10856869 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10856869 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 28829665 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28829665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7914235 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25185099 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25185099 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25185099 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 31847602 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31274244 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23872824 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 16615287 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16615287 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 14571186 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10729391 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10729391 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20464599 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 11849659 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21624490 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 17608233 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 25078374 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28284167 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 26041677 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 22833195 — Biomarker: CTNNA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CTNNA2; CAPR
Study 7641736 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 2655685 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19092650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17053552 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17053552 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17053552 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2192099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 457528 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 31781694 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 24220935 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24220935 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28599676 — Biomarker: SPN mRNA
Type: Predictive Biomarker (PRD)
Genes: SPN; CD43
Study 25923462 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 12624295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8656666 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8656666 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1877363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25117302 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25117302 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19323930 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 19323930 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11158043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9576193 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25257259 — Biomarker: TYR mRNA
Type: Predictive Biomarker (PRD)
Genes: TYR
Study 24171985 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 21843028 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 19661833 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 9166835 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11378012 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8111807 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3298405 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25500684 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 29676944 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29676944 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 11448906 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 11448906 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8596756 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 8596756 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 8596756 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8596756 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14693625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12563568 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11597291 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25171906 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 20973685 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 1307052 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31005923 — Biomarker: ACAD8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAD8; ARC42; IBD
Study 28843031 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26823294 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17584825 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 16132888 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12034024 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 8703666 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 8703666 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 2147175 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2147175 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 2147175 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2147175 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25979300 — Biomarker: ANGPTL8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANGPTL8; C19orf80; RIFL; UNQ599/PRO1185
Study 22852117 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15526058 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 29987027 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 27793135 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 23327604 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 7564347 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7564347 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7564347 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23569345 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 23569345 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 23569345 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 17892982 — Biomarker: FBN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBN1; FBN
Study 11474773 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 3260759 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29880010 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23284036 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 21640089 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18039239 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 9652994 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10150434 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 31857217 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25572878 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 24928083 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 17244785 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17244785 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16286549 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 14600187 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16357163 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51