AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 7946102 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25403587 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23234805 — Biomarker: EDNRA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDNRA; ETA; ETRA
Study 21813840 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16673379 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 15112170 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1404350 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26700096 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 20582542 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20582542 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20582542 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 20582542 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 10366800 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 10366800 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 10366800 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 1928212 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 23074206 — Biomarker: DDIT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT4; REDD1; RTP801
Study 7488479 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 19711440 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11243303 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8021901 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7006616 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 30882927 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 26070127 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 26181252 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26181252 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 26181252 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 26181252 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19420195 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 15253732 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15253732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15253732 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15253732 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 9305229 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 25495543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22795063 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 12520156 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 23682797 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21950736 — Biomarker: ADORA2A mRNA
Type: Predictive Biomarker (PRD)
Genes: ADORA2A; ADORA2
Study 2654321 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8004613 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29980233 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21110088 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12660669 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12660669 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12660669 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12660669 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12660669 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 10735416 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 10735416 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27394134 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 20686425 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 11824857 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31827356 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 25345354 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1279299 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1279299 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24293660 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15966884 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 8607399 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28993070 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 27287084 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18818160 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7048877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26017328 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 21350839 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 12479763 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12479763 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9489629 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 8106695 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28300357 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25877139 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23485720 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28931404 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 17701167 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23816039 — Biomarker: RYR1
Type: Safety Biomarker (SAF)
Genes: RYR; PPP1R137
Study 23816039 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23816039 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23816039 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16214632 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 15474696 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8061901 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 3421209 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22212275 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22212275 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 22212275 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8733683 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 8733683 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 8733683 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 24368307 — Biomarker: CNTF mRNA
Type: Predictive Biomarker (PRD)
Genes: CNTF
Study 18974967 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11577993 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 11577993 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 11577993 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22447494 — Biomarker: IL16
Type: Safety Biomarker (SAF)
Genes: LCF; IL-16; prIL-16; HsT19289; FLJ42735; FLJ16806
Study 20470337 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 15919488 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6475654 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30392345 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 26337132 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22425474 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 22425474 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 20379679 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 1332463 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1332463 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21380565 — Biomarker: Angiopoietin-1
Type: Monitoring Biomarker (MOI)
Genes: ANGPT1; KIAA0003
Study 20212256 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 8941005 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1338084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31044234 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21999631 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8453797 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8453797 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26321012 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16636857 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 3167937 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28199799 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19373128 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 2356812 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30298469 — Biomarker: BTC mRNA
Type: Predictive Biomarker (PRD)
Genes: BTC
Study 30298469 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30298469 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 31720788 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 26574567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7815572 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31085679 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 31085679 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 25398689 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22260858 — Biomarker: UCP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP1; SLC25A7; UCP
Study 15375787 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15375787 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9733054 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9733054 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 22041483 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 14660727 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study 12013487 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12013487 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24227120 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24227120 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22804943 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 19789153 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9197291 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7951525 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10472212 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 10472212 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 10472212 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1651894 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 1651894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25913664 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24091694 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24091694 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 11986563 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 12873166 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 7664720 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26580831 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26580831 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21818510 — Biomarker: GSS mRNA
Type: Predictive Biomarker (PRD)
Genes: GSS
Study 9287262 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8346578 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 30679318 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30679318 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 27646064 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 20411996 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 20411996 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20411996 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20411996 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18182939 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15806847 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 25236838 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 14752209 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30932776 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31740871 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 31249252 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21094811 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 15625770 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15625770 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15625770 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10822211 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10822211 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10822211 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31929250 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26424102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15655272 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15251771 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15251771 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15251771 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8350218 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10204597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8833935 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8833935 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 28181675 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12929472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12929472 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27904554 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 27904554 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18492125 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 14688560 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29455372 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 29455372 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 16021438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8834418 — Biomarker: HPDL mRNA
Type: Predictive Biomarker (PRD)
Genes: HPDL; GLOXD1
Study 4017421 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27863809 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 25003166 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 20367560 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12699301 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10626559 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 8665546 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 8665546 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 16500361 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16500361 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16500361 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 10996336 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 10996336 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 2527542 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26471240 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 28899951 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28899951 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 28899951 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 1627437 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25153936 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2253661 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2253661 — Biomarker: Urine free cortisol
Type: Surrogate Endpoint (SUR)
Study 23890352 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 23890352 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22186252 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 22186252 — Biomarker: OAF mRNA
Type: Predictive Biomarker (PRD)
Genes: OAF; NS5ATP13TP2
Study 12850387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22212248 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study 11686823 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 30055974 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 27034624 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27034624 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22241810 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 17534855 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study 8712137 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8712137 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29727332 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 29051561 — Biomarker: MAGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAGT1; IAG2; PSEC0084; UNQ628/PRO1244
Study 29051561 — Biomarker: KLRK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRK1; D12S2489E; NKG2D
Study 29051561 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 1289512 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30091443 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 27103031 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 20166008 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1684154 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26644369 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 7743684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)