AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 26335787 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26335787 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 26335787 — Biomarker: TLR2
Type: Predictive Biomarker (PRD)
Genes: TIL4; CD282
Study 16796157 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 8471122 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 29859385 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29859385 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29859385 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 29859385 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24420547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16928483 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 21142442 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24073995 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11779901 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29635951 — Biomarker: AIP mRNA
Type: Predictive Biomarker (PRD)
Genes: AIP; XAP2
Study 18800457 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18800457 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18800457 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18800457 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28453838 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study 9735661 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25728587 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11549430 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 9820373 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 2845011 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 24943283 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20921347 — Biomarker: FBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBP1; FBP
Study 12578870 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 12578870 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8250364 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29205049 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29205049 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15309420 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25051124 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21715537 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 21715537 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 21715537 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21715537 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 10881828 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10881828 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18716298 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17719932 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24043395 — Biomarker: TBP mRNA
Type: Predictive Biomarker (PRD)
Genes: TBP; GTF2D1; TF2D; TFIID
Study 20557937 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 17184595 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 30550892 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 30550892 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 12354426 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 30303923 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 30303923 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8842502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24084344 — Biomarker: CYP1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A1
Study 24084344 — Biomarker: CYP1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1B1
Study 24084344 — Biomarker: EPHX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPHX1; EPHX; EPOX
Study 24084344 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 24084344 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 21820130 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19730391 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27647662 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24076297 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28103388 — Biomarker: CRABP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CRABP2
Study 28103388 — Biomarker: LORICRIN mRNA
Type: Predictive Biomarker (PRD)
Genes: LORICRIN; LOR; LRN
Study 28103388 — Biomarker: KRT4 mRNA
Type: Predictive Biomarker (PRD)
Genes: KRT4; CYK4
Study 23039968 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 11034112 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9365082 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9365082 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31970414 — Biomarker: HDAC8 mRNA
Type: Predictive Biomarker (PRD)
Genes: HDAC8; HDACL1; CDA07
Study 31970414 — Biomarker: SMAD3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMAD3; MADH3
Study 31970414 — Biomarker: SIRT7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIRT7; SIR2L7
Study 31970414 — Biomarker: SMAD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMAD4; DPC4; MADH4
Study 10486645 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 10486645 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8735683 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 31990350 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 31990350 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 31990350 — Biomarker: TLR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR1; KIAA0012
Study 31990350 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 31990350 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 7946179 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 7946179 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26314530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10370677 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28264692 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 28264692 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 28264692 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23332183 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 23332183 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23332183 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 3246316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29590407 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 18077218 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 1328364 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1328364 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6108817 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27853163 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20390272 — Biomarker: GDA mRNA
Type: Predictive Biomarker (PRD)
Genes: GDA; KIAA1258
Study 28549665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18487628 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8840941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17959578 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 17959578 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29028973 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29028973 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 25200399 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 20048183 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 18221472 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18221472 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 16635225 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study 2024739 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30636832 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29063309 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27743448 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 27743448 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27743448 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25373733 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25373733 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 22674882 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21677123 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 21677123 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21677123 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 21677123 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15704045 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12036186 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12036186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31891694 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23470315 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23470315 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 20932656 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 8256886 — Biomarker: DDR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 8256886 — Biomarker: TAC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAC1; NKA; NKNA; TAC2
Study 23897106 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23897106 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24721240 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 15894667 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 31295009 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 26346590 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 26346590 — Biomarker: TMEM37 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMEM37; PR
Study 24269033 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 24269033 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 22702508 — Biomarker: CXCR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR2; IL8RB
Study 22702508 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 28050914 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 14530912 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8330466 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 20021624 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7341285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28865493 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28865493 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26650562 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21212911 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 1571851 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 31752260 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 31752260 — Biomarker: ULK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ULK1; KIAA0722
Study 31752260 — Biomarker: SQSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SQSTM1; ORCA; OSIL
Study 21357805 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30605397 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 30605397 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 22964716 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 22964716 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 22964716 — Biomarker: ABCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 14998852 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 11514369 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 11514369 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 11514369 — Biomarker: TIMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TIMP2
Study 11514369 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 9700472 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9700472 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 9700472 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8077368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23219787 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 20309015 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 20309015 — Biomarker: SULT1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SULT1A1; STP; STP1; OK/SW-cl.88
Study 20309015 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 15390350 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7890014 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10931390 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23771450 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14640465 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14640465 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8383638 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21256606 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 20392970 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26525102 — Biomarker: PLA2G4A mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G4A; CPLA2; PLA2G4
Study 26525102 — Biomarker: PLA2G6 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G6; PLPLA9
Study 26525102 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23674289 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 18413554 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18413554 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10601051 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 10601051 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 23567070 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9024171 — Biomarker: CYP2E1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2E1; CYP2E
Study 9024171 — Biomarker: SLC38A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 31362299 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 30282670 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24164001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8612412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24270198 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 19249429 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 19249429 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 15097437 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 30762945 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30340488 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 27806634 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 1953212 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24488700 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 24488700 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 24488700 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 12398998 — Biomarker: DACH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DACH1; DACH
Study 9534093 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25075773 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 25075773 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25075773 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 25075773 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 17471343 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 23799553 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19322744 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17911549 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 28644114 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 18250972 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 18250972 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 15035763 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 1606067 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 1606067 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 30099933 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20727522 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20727522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15630488 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 15630488 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12859158 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12859158 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27718369 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26202488 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23176888 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3