AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 8467568 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 24214232 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 25814432 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10421878 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 8574276 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30244181 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 30244181 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 22274169 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8712446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25947235 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 15309011 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9491017 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30339244 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 28185715 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26192975 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7696451 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2821947 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24438902 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 24438902 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 24438902 — Biomarker: CD83 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD83
Study 24438902 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 23519586 — Biomarker: APLNR mRNA
Type: Predictive Biomarker (PRD)
Genes: APLNR; AGTRL1; APJ
Study 11179104 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29438200 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 29438200 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21429222 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 14581425 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 14581425 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 14581425 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8695025 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22529513 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31843964 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 31843964 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17944585 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17944585 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9217822 — Biomarker: TNC mRNA
Type: Predictive Biomarker (PRD)
Genes: TNC; HXB
Study 9217822 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 9217822 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 26422197 — Biomarker: CDKN1B mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN1B; KIP1; p27
Study 22945416 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22945416 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21494604 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21494604 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 18484235 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18484235 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8348392 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8348392 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21039930 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17569876 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 28167849 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 25740691 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28574605 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 7908531 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7908531 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27083384 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 26639027 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 15466324 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9483471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7509259 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 7509259 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26354521 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11046209 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9504815 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 7828457 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 22415082 — Biomarker: UCP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP2; SLC25A8
Study 22415082 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 15855695 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11062382 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 21677124 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18826631 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 18826631 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11252549 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9628275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14816 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30814109 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30814109 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30814109 — Biomarker: miR-140
Type: Safety Biomarker (SAF)
Genes: MIR140
Study 18036682 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18462734 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 11726036 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 11726036 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11726036 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3280158 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31839530 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30973547 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30973547 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11061603 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 24280948 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 22496161 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 22496161 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22496161 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 22496161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12616982 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 12616982 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12616982 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10518081 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25599299 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23700938 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16761153 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15486569 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23598540 — Biomarker: FABP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FABP4
Study 8359959 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16998214 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 30636184 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 16791015 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 16791015 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23122211 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 23122211 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 20371683 — Biomarker: Cyclin-dependent kinase inhibitor 1
Type: Safety Biomarker (SAF)
Genes: CDKN1A
Study 20371683 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 20371683 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 20693499 — Biomarker: SPTB mRNA
Type: Predictive Biomarker (PRD)
Genes: SPTB; SPTB1
Study 10067800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1449564 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 30915660 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30580268 — Biomarker: CPOX mRNA
Type: Predictive Biomarker (PRD)
Genes: CPOX; CPO; CPX
Study 12824969 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 6285318 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 16332662 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 12417875 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25827670 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 25827670 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25827670 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 23161645 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7994805 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28659213 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 21792296 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18055864 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 14586800 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10487558 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 2265735 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30877658 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28760939 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28760939 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26142514 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 26142514 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25131073 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15494612 — Biomarker: AKR1C1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKR1C1; DDH; DDH1
Study 15494612 — Biomarker: AKR1C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKR1C2; DDH2
Study 15494612 — Biomarker: AKR1C3 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKR1C3; DDH1; HSD17B5; KIAA0119; PGFS
Study 15494612 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 7621455 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 26488675 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 26488675 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 7603075 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31731609 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15559609 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 24231627 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20928842 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 16980115 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16980115 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8857325 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 8857325 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 27913306 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19542866 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15147545 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 7407516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29148144 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2981491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24488143 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17912794 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 17912794 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 12048334 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 1623913 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25462201 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 10903015 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30487248 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 10999778 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29178617 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29178617 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28391397 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21192237 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 25456892 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22882570 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 23073596 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 19915083 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19915083 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19915083 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16500662 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 2215826 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31421426 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 31421426 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 31421426 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12585782 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31755037 — Biomarker: HSPA8 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA8; HSC70; HSP73; HSPA10
Study 31755037 — Biomarker: Heat shock 70 kDa
Type: Safety Biomarker (SAF)
Study 28500516 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 31145308 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885
Study 31145308 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 31145308 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31145308 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31145308 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 31145308 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 31145308 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25331845 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21471085 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 17418218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12559860 — Biomarker: IL11
Type: Predictive Biomarker (PRD)
Genes: IL-11; AGIF
Study 22331056 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11112238 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11112238 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9364981 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29777404 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29777404 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12701826 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 31246370 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 20666950 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 26293451 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11491207 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11491207 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7846219 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30475960 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30475960 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 28331914 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25434501 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8836934 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 20634175 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20634175 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20634175 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17624174 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 31838046 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31838046 — Biomarker: NFKBIA mRNA
Type: Predictive Biomarker (PRD)
Genes: NFKBIA; IKBA; MAD3; NFKBI
Study 31838046 — Biomarker: Arginase-1
Type: Safety Biomarker (SAF)
Genes: ARG1
Study 31838046 — Biomarker: PHACTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PHACTR1; KIAA1733; RPEL1
Study 12819076 — Biomarker: CTBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CTBS; CTB
Study 30115656 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 30172196 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26843153 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22476807 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 10189121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7750002 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 26730818 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22822007 — Biomarker: NOD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOD2; CARD15; IBD1
Study 20652333 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17211705 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 11303324 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 6365501 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 23958540 — Biomarker: GUCY2C mRNA
Type: Predictive Biomarker (PRD)
Genes: GUCY2C; GUC2C; STAR
Study 10834715 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10834715 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2