AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 15572589 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15572589 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7623005 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2821080 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2821080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26178748 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 16259942 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20127563 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 20127563 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 20127563 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 20127563 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 20127563 — Biomarker: Angiopoietin 1 receptor
Type: Monitoring Biomarker (MOI)
Genes: TEK; TIE2; VMCM; VMCM1
Study 9735677 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 31319637 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19736179 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 28851099 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28851099 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 28851099 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 22441004 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 20202819 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17699341 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 8923574 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 10450013 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 31269677 — Biomarker: miR-143
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR143
Study 31269677 — Biomarker: miR-195-5p
Type: Monitoring Biomarker (MOI)
Genes: MIR195
Study 31269677 — Biomarker: miR-30a
Type: Safety Biomarker (SAF)
Genes: MIR30A
Study 19361362 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8874677 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 1412754 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3927371 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 26037276 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 24246616 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 24246616 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 25146059 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 23742676 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 23742676 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 20058619 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20058619 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20058619 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20058619 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10917406 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22990943 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 22990943 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22990943 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 22990943 — Biomarker: VGF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: VGF
Study 22990943 — Biomarker: FKBP5 mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: FKBP5; AIG6; FKBP51
Study 22990943 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 16184460 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16184460 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16184460 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 27733180 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 18191416 — Biomarker: SNAP25 mRNA
Type: Predictive Biomarker (PRD)
Genes: SNAP25; SNAP
Study 7449302 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15129412 — Biomarker: SFPQ mRNA
Type: Predictive Biomarker (PRD)
Genes: SFPQ; PSF
Study 1203854 — Biomarker: POMP mRNA
Type: Predictive Biomarker (PRD)
Genes: POMP; C13orf12; UMP1; HSPC014; HSPC036; PNAS-110
Study 26160625 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26160625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30871628 — Biomarker: KIR3DL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KIR3DL1; CD158E; NKAT3; NKB1
Study 25648736 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25648736 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25648736 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22974280 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 6939007 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16447644 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16447644 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9824407 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 8109551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8109551 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8267066 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23468980 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21527583 — Biomarker: TGFBR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TGFBR1; ALK5; SKR4
Study 21527583 — Biomarker: ALK
Type: Predictive Biomarker (PRD)
Genes: CD246; ALK1
Study 21527583 — Biomarker: LTBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LTBP1
Study 21527583 — Biomarker: LTBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: LTBP4
Study 21527583 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 21527583 — Biomarker: TGFB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TGFB2
Study 21527583 — Biomarker: TGFBR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TGFBR2
Study 21527583 — Biomarker: SMAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMAD1; BSP1; MADH1; MADR1
Study 21527583 — Biomarker: Mothers against decapentaplegic homolog 2
Type: Predictive Biomarker (PRD)
Genes: SMAD2; MADH2; MADR2
Study 21527583 — Biomarker: SMAD3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMAD3; MADH3
Study 21527583 — Biomarker: SMAD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMAD4; DPC4; MADH4
Study 24850844 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 20883232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9440387 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 6340806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16815260 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 24625508 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2238575 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30249211 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 30249211 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 15926017 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 10340911 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 7569455 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22791300 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 22791300 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20106932 — Biomarker: NOCT mRNA
Type: Predictive Biomarker (PRD)
Genes: NOCT; CCR4; CCRN4L; NOC
Study 29302858 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24584818 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20507841 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 24127924 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 18081359 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 30813779 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30948622 — Biomarker: DIAPH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DIAPH2; DIA
Study 18848470 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 17128343 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 9207470 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 8256988 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31914620 — Biomarker: TFEB mRNA
Type: Predictive Biomarker (PRD)
Genes: TFEB; BHLHE35
Study 31914620 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 27988144 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 15080791 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 24423341 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 24423341 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 24423341 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24423341 — Biomarker: ADAM17 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM17; CSVP; TACE
Study 24423341 — Biomarker: TIMP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TIMP3
Study 27592206 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27592206 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24593836 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 24593836 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8622612 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 25694037 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25694037 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25694037 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6129380 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26707418 — Biomarker: ALPI mRNA
Type: Predictive Biomarker (PRD)
Genes: ALPI
Study 22422931 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29164421 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29164421 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20159131 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18627323 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 11821720 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7130553 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 26390517 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 24959775 — Biomarker: MTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 19750404 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 12632413 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 10535720 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8767243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6625217 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 31657166 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 31657166 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26848137 — Biomarker: APOC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOC3
Study 11463600 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 9875685 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2607521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30855722 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30855722 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 26531275 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 26531275 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 26687836 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 26687836 — Biomarker: PDGFRA mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 26687836 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 10574598 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 8665034 — Biomarker: TAC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAC1; NKA; NKNA; TAC2
Study 27809891 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 29481636 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 9622166 — Biomarker: FBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBP1; FBP
Study 7619649 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2569309 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26590673 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26590673 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study 15378665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26988367 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26988367 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22890714 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 22890714 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 20135144 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 18056004 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 18056004 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 16260969 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 7572582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 630793 — Biomarker: CPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPZ
Study 630793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27130927 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15093884 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 11422755 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25319120 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 25319120 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8338056 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 27032107 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20591499 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 18714150 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 1418029 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 31798713 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 25015912 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 30478814 — Biomarker: CNR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNR1; CNR
Study 21415069 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12406891 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 12406891 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18389675 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 18389675 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 15804248 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10233426 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30829316 — Biomarker: ZEB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZEB1; AREB6; TCF8
Study 30548426 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 30548426 — Biomarker: FOXO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXO1; FKHR; FOXO1A
Study 30548426 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 30548426 — Biomarker: TRIM63 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 21813573 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31634532 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8615323 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8615323 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30768429 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16969378 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12121721 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 25226336 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 25226336 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20368213 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 20368213 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28330458 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 25576682 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 10710119 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20044530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23272667 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16433897 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31963773 — Biomarker: FMOD mRNA
Type: Predictive Biomarker (PRD)
Genes: FMOD; FM; SLRR2E
Study 29242937 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 29242937 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 29242937 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29242937 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 25515056 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 14557432 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14557432 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 29992524 — Biomarker: NR4A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR4A1; GFRP1; HMR; NAK1
Study 15855656 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 26547399 — Biomarker: DCC mRNA
Type: Predictive Biomarker (PRD)
Genes: DCC; IGDCC1
Study 18436564 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 18436564 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18436564 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10348466 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 2157983 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 6368246 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31305326 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 28918548 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28918548 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28918548 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 22552027 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20545561 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12070197 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 8649942 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 8649942 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 37868 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24873720 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU