AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 15459594 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 16303616 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 1119734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1822264 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1822264 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6124653 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29470854 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17631786 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 17631786 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 16140229 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 16140229 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31028165 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 28504321 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15233975 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15233975 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15233975 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15233975 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9237960 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 29766325 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25156780 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 25156780 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15370682 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 11535316 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 9692077 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24042479 — Biomarker: Fatty acid amide hydrolase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: FAAH; FAAH1
Study 30963443 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18212034 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 18212034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27912960 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27912960 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20545210 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12752555 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 12752555 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 9467046 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 28765681 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 28765681 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22174580 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16543688 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16543688 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16543688 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30440010 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30440010 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 30440010 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18279765 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19190970 — Biomarker: miR-143
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR143
Study 19190970 — Biomarker: miR-205
Type: Safety Biomarker (SAF)
Genes: MIR205
Study 3296668 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31098739 — Biomarker: ZNF471 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZNF471; ERP1; KIAA1396
Study 31098739 — Biomarker: THOC5 mRNA
Type: Predictive Biomarker (PRD)
Genes: THOC5; C22orf19; KIAA0983
Study 22650799 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11100017 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9171252 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2942753 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 2942753 — Biomarker: DBI mRNA
Type: Predictive Biomarker (PRD)
Genes: DBI
Study 2942753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2893527 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31196847 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 25970511 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 19497447 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19497447 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19497447 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9024733 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9024733 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8331091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24390808 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12544908 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 6129141 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29326421 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29326421 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9867157 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 7638802 — Biomarker: P4HB mRNA
Type: Predictive Biomarker (PRD)
Genes: P4HB; ERBA2L; PDI; PDIA1; PO4DB
Study 2765808 — Biomarker: OTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 1093756 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12577187 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22657838 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8050544 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 342217 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30193971 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 23916874 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 14722167 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 9024026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2871744 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 15925121 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 1726002 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22159672 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21367594 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 19411954 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 9089939 — Biomarker: BAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAK1; BAK; BCL2L7; CDN1
Study 8506440 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27565012 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 24845208 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16953457 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 29879602 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 20652004 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20652004 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17645503 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 26965694 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25318787 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22074122 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12171961 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 12171961 — Biomarker: MUC5AC mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MUC5AC; MUC5
Study 12171961 — Biomarker: MUC6 mRNA
Type: Predictive Biomarker (PRD)
Genes: MUC6
Study 8508666 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31812457 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 24404816 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24404816 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11738120 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 25648379 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 25648379 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15307695 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15307695 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15307695 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11780351 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9280714 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9280714 — Biomarker: CGN mRNA
Type: Predictive Biomarker (PRD)
Genes: CGN; KIAA1319
Study 9280714 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 2883575 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31231923 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 21632472 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 21632472 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9450156 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28671856 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28671856 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16837736 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 8093139 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16469980 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31805386 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 31805386 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31805386 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28185713 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28185713 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14676595 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 25452300 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14656250 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31205187 — Biomarker: PDE10A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE10A
Study 28593920 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 28593920 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 28593920 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 9081352 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 18046048 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 18046048 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 18046048 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17057417 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10746815 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1614074 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12939889 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6134137 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 6134137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24768191 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24768191 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 24768191 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16187006 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 11696738 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 25833957 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 19167733 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 11248742 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 27978867 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19894330 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 15100375 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24955642 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 24955642 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 22499290 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17620073 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 22520631 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17588396 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17588396 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17588396 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 17588396 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 17588396 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 17588396 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11454380 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 30607545 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 29212812 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23261355 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 9068934 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 8103648 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16234451 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 10459902 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 31759193 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 12784383 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 12784383 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 12784383 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18023335 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 18023335 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9079233 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3717956 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 7969280 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26190830 — Biomarker: Nasal potential difference
Type: Pharmacodynamic Biomarker (PDY)
Study 22120765 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12187023 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8697717 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22819265 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 10726112 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10726112 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23799706 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21836369 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study 21836369 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10690135 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 26926372 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 24570273 — Biomarker: MTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 24570273 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24570273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24570273 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15060416 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 15060416 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 9827406 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29417832 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23715755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10674226 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10674226 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8369008 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 31948296 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31948296 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 24974387 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 20673378 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20673378 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12392587 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19049703 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 19049703 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10889804 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10889804 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 1467514 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 26849844 — Biomarker: ELK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELK3; NET; SAP2
Study 25391194 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12940609 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6507426 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6507426 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25913873 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 11110418 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 1922908 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 1922908 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 24669014 — Biomarker: Growth/differentiation factor 15
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 27990643 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 23343964 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 23343964 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18786982 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18786982 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18786982 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 187356 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 21646616 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2