AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 1672870 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31247504 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 24251120 — Biomarker: NANOS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS1; NOS1
Study 17708607 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 15087291 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2567740 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 182105 — Biomarker: TERF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TERF1; PIN2; TRBF1; TRF; TRF1
Study 21904105 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 30167757 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 22836071 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16154437 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8895267 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27621597 — Biomarker: Th2 cell
Type: Safety Biomarker (SAF)
Study 21051656 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 7625665 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 25271015 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23496897 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 7883133 — Biomarker: KCNN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNN1; SK
Study 18307280 — Biomarker: FCGR3A mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 18307280 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18307280 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 18307280 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10716466 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10716466 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27653383 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 25639140 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23686277 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 15681945 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 10362454 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 7723156 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7723156 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7362505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28779963 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18079221 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 8942440 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27364372 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 12769161 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12769161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30473019 — Biomarker: MPST mRNA
Type: Predictive Biomarker (PRD)
Genes: MPST; TST2
Study 15868442 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 8689817 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 30968542 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 30968542 — Biomarker: CILP mRNA
Type: Predictive Biomarker (PRD)
Genes: CILP; UNQ602/PRO1188
Study 24402636 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24402636 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17095745 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 9813583 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21840914 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16680923 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9726718 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 27966565 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25370206 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 21640360 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18963025 — Biomarker: TNFSF10 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF10; APO2L; TRAIL
Study 18963025 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 16880095 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 12964783 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30730346 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 28126300 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 23095307 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21172842 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17652181 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 11896478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28100551 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19064822 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 19499272 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7799337 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 25146365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21592715 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 20664127 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24283773 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 19056900 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 16563974 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6751003 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27460618 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 27460618 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19685757 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 8526620 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 2405964 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 20535962 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 6427714 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30998422 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 12672711 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12672711 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 12672711 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10744143 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10744143 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 2413307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30452784 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30452784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27717303 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27717303 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 27717303 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27717303 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 1461544 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26704011 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18444869 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18444869 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18444869 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9052302 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8379601 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 23525434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16622748 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 2969315 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2969315 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31937274 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 26156941 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 17846310 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 15535408 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9516068 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7759428 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 7759428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16546755 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 16546755 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 10896637 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10896637 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10896637 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26946333 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 21684022 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 21684022 — Biomarker: GDNF mRNA
Type: Predictive Biomarker (PRD)
Genes: GDNF
Study 21684022 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 21684022 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 17388762 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7564369 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7564369 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29402509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8945675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28142075 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 28142075 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 22595153 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 22595153 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 22595153 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15323595 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 23758279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18809153 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10795662 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8641640 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29315212 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 29315212 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22805873 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 22805873 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 22805873 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 9139554 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30042362 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26760452 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24951991 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 20210614 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 20210614 — Biomarker: PRSS27 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRSS27; MPN; UNQ1884/PRO4327
Study 31277073 — Biomarker: BMPR1B mRNA
Type: Predictive Biomarker (PRD)
Genes: BMPR1B
Study 31277073 — Biomarker: GNAS mRNA
Type: Predictive Biomarker (PRD)
Genes: GNAS; GNAS1
Study 31277073 — Biomarker: GHR mRNA
Type: Predictive Biomarker (PRD)
Genes: GHR
Study 31277073 — Biomarker: SRD5A2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SRD5A2
Study 24341367 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 19615128 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 8512099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22781525 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15753747 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 28816833 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 23500267 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 15298946 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15298946 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11735185 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31233893 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 31233893 — Biomarker: FANCA mRNA
Type: Predictive Biomarker (PRD)
Genes: FANCA; FAA; FACA; FANCH
Study 19439813 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 19439813 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31809216 — Biomarker: AMPH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMPH; AMPH1
Study 25074639 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 16562643 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 16562643 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20969664 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 9041968 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29870868 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20520603 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 16651305 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12792354 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9952072 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9952072 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 24299019 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24299019 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21157172 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16158081 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 23279372 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 21995804 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 18812677 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18812677 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10988110 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26948284 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24709636 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17889355 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 17889355 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 14712432 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11842483 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 28545589 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 21895947 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1422320 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 1422320 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28961803 — Biomarker: CCR9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR9; GPR28
Study 18311576 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 14597524 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 14597524 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 1578626 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27644242 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 25208075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20531106 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20531106 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 20531106 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 24108780 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 7662225 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2758384 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21755327 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 19663689 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19663689 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 27584715 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 20172127 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 18271430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30813125 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 28187506 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 28187506 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 28187506 — Biomarker: NR1I2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1I2; PXR
Study 26125924 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19366826 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 19366826 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 19366826 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19366826 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 19366826 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 17190733 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17190733 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31512815 — Biomarker: ADORA2A
Type: Safety Biomarker (SAF)
Genes: RDC8
Study 24345793 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 18595436 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11863118 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 2076391 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 2076391 — Biomarker: TET1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET1; CXXC6; KIAA1676; LCX
Study 22143010 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3534584 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26254196 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26254196 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 26254196 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 19502018 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11082213 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9032569 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1456855 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1456855 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1456855 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31171092 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31171092 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19046724 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19046724 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 10570675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10570675 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10570675 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 29097225 — Biomarker: NES mRNA
Type: Predictive Biomarker (PRD)
Genes: NES; Nbla00170
Study 16052765 — Biomarker: TPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH1; TPH; TPRH; TRPH
Study 7734252 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 7734252 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22219027 — Biomarker: MAP3K10 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP3K10; MLK2; MST
Study 14735048 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 31492766 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF