AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 8931831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30394919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29577973 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 24092385 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17588297 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8396204 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24068395 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 24068395 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 19912736 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19912736 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19912736 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11439963 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study 15718840 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 14521596 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 1894758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26925155 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26925155 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22247116 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 30194031 — Biomarker: CYP17A1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CYP17A1; CYP17; S17AH
Study 30194031 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 30194031 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 30951597 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 30951597 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30951597 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28661759 — Biomarker: TOP2A mRNA
Type: Predictive Biomarker (PRD)
Genes: TOP2A; TOP2
Study 15708302 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 342691 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 31190359 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25597870 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21729238 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21729238 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 24446242 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17400981 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15567812 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9789972 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18633170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18633170 — Biomarker: ADIPOQ mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 31614909 — Biomarker: MUC5AC mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MUC5AC; MUC5
Study 31614909 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 15167732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19959168 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19959168 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19959168 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19959168 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16280273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7785755 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 6246620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28898379 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23478273 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 11451594 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29617836 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 25154151 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18334511 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23720367 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19299808 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3279968 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 17548729 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 10436966 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 22050040 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 20738023 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10220833 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 10220833 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29237134 — Biomarker: NAT8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NAT8; CML1; GLA; TSC501
Study 27732968 — Biomarker: SBF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SBF2; CMT4B2; KIAA1766; MTMR13
Study 22816732 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 22816732 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22816732 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9086386 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9086386 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 18640939 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 24081232 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study 3046791 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25843292 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10823386 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10823386 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10823386 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 26122803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16138585 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 19744828 — Biomarker: GAD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD2; GAD65
Study 16182105 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7517172 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30536191 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 25749297 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12584283 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 26848117 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 9735502 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7523961 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 29940335 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 27065472 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 27065472 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 23511562 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 27305952 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 11152917 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11152917 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16213287 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10075386 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30019072 — Biomarker: SBSN mRNA
Type: Predictive Biomarker (PRD)
Genes: SBSN; UNQ698/PRO1343
Study 11300658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2688507 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31490376 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 23768736 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 20166337 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20166337 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29229363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29229363 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26945711 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15875094 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12867219 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12867219 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11955025 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11955025 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11955025 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24135218 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24135218 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21438793 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21438793 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21438793 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21438793 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9678089 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 9678089 — Biomarker: SERPINA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA6; CBG
Study 31577697 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26112886 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 26112886 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10672134 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8410923 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 17971530 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 22364262 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 22364262 — Biomarker: MMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP2; CLG4A
Study 17442512 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 18068613 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15168319 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 15168319 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15168319 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 15168319 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 15168319 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29682995 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 29682995 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26972635 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26972635 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26972635 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30665814 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 8150641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2834976 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2834976 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15590442 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 11185637 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3887159 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29628593 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29628593 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 29628593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26661403 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 26661403 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 16137355 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 10803490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31048181 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 26062689 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26062689 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22248554 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22248554 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 19704107 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16717477 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 16717477 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 7995007 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7995007 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24433434 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19539427 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 8887822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31571412 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21831714 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15070938 — Biomarker: MAX mRNA
Type: Predictive Biomarker (PRD)
Genes: MAX; BHLHD4
Study 11317472 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11317472 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2967183 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30380020 — Biomarker: HBEGF mRNA
Type: Predictive Biomarker (PRD)
Genes: HBEGF; DTR; DTS; HEGFL
Study 21481280 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21491487 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21491487 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2967304 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12655529 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 25518574 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28651697 — Biomarker: ABCC6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC6; ARA; MRP6
Study 21863028 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 1300436 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31756267 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 29704641 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29704641 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 27273977 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 24166468 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30668423 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30668423 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26790200 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23125396 — Biomarker: MCCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCCC2; MCCB
Study 1706012 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26044067 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 26044067 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 26044067 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 24124717 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19616720 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15364766 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 8076657 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21808851 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 2686485 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31960497 — Biomarker: IL1R2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1R2; IL1RB
Study 31960497 — Biomarker: SRD5A2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SRD5A2
Study 30037019 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30037019 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15816586 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9714526 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21851202 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 19469885 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15521232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23804232 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 23804232 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8748408 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30571235 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24368552 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 9860107 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26188167 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 26188167 — Biomarker: Auditory mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 14677616 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 3068344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3068344 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19564636 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 28841229 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26983946 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 21876511 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25416514 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 8729587 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 8729587 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8729587 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7049710 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28814161 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16306499 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11887180 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 30585337 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30585337 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 19379588 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17321919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7802307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24548259 — Biomarker: SSB mRNA
Type: Predictive Biomarker (PRD)
Genes: SSB
Study 23706327 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21718836 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21718836 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 21718836 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 21718836 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19938555 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11669215 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 22595313 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22595313 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2