AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT03943342 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study NCT04188925 — Biomarker: SP9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP9
Study NCT02886013 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study NCT04086875 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT01473927 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00609271 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00609271 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03457233 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT04344327 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT03112590 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03112590 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT02021968 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT02457585 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03509298 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study NCT04663854 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT02933593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03624530 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT03624530 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT01698281 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT01698281 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03060577 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study NCT03060577 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01460160 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT01460160 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT04082091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00003881 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01639508 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT01639508 — Biomarker: ROS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROS1; MCF3; ROS
Study NCT01639508 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT01639508 — Biomarker: AXL mRNA
Type: Predictive Biomarker (PRD)
Genes: AXL; UFO
Study NCT00847171 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00847171 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03959228 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study NCT04269278 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01488565 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT01552122 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01461330 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02107677 — Biomarker: IVNS1ABP mRNA
Type: Predictive Biomarker (PRD)
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068
Study NCT00415571 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study NCT05172895 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT03341403 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study NCT02004314 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT02004314 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study NCT04406116 — Biomarker: HCLS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HCLS1; HS1
Study NCT02788669 — Biomarker: LRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LRP1; A2MR; APR
Study NCT02788669 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study NCT02799888 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study NCT01943097 — Biomarker: DDC mRNA
Type: Predictive Biomarker (PRD)
Genes: DDC; AADC
Study NCT03203278 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00814879 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study NCT01343225 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT01343225 — Biomarker: CYP24A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP24A1; CYP24
Study NCT01462162 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01359540 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03906227 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study NCT03906227 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study NCT04403100 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT02934828 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02934828 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00621972 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT00621972 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT02343887 — Biomarker: CPE mRNA
Type: Predictive Biomarker (PRD)
Genes: CPE
Study NCT01689506 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03778229 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT03778229 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03252184 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT02903511 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study NCT05458726 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00385086 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00072969 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT01419535 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00813228 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT00813228 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study NCT03173495 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study NCT03173495 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT02278471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04071119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01300117 — Biomarker: ADAMTS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT01604681 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study NCT01810744 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02569489 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02374632 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study NCT03319290 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study NCT02438072 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study NCT02438072 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study NCT02438072 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study NCT02438072 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study NCT02438072 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT03932136 — Biomarker: 14-3-3 protein sigma
Type: Predictive Biomarker (PRD)
Genes: SFN; HME1
Study NCT03811600 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02903576 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study NCT00315068 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00674167 — Biomarker: RUNX3 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX3; AML2; CBFA3; PEBP2A3
Study NCT04476823 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT00785122 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00035815 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study NCT04430530 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study NCT04430530 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study NCT03465657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03346863 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study NCT00974779 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04587180 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01214512 — Biomarker: CD24 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD24; CD24A
Study NCT00599781 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study NCT03127748 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study NCT01070797 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT01737164 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study NCT04589494 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00923091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02492711 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03921372 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01857310 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study NCT01860846 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00949650 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00949650 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00199186 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT00199186 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT01686503 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT05417529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02758366 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00999752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04722133 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03414918 — Biomarker: KCNJ5 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNJ5; GIRK4
Study NCT03414918 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01988038 — Biomarker: PRKD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKD1; PKD; PKD1; PRKCM
Study NCT01172171 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT00379938 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT02521350 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT02832583 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT02770261 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01757457 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04791891 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study NCT00926068 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study NCT01751646 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT00945191 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study NCT02187029 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study NCT00077233 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02495233 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03951428 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study NCT03300453 — Biomarker: NAGLU mRNA
Type: Predictive Biomarker (PRD)
Genes: NAGLU; UFHSD1
Study NCT04642183 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT01066663 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study NCT02079441 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04361097 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT02710500 — Biomarker: DYSF mRNA
Type: Predictive Biomarker (PRD)
Genes: DYSF; FER1L1
Study NCT03927599 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study NCT04627519 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT00274326 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study NCT04539587 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT00471471 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT00210262 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT00210262 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02360748 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT02360748 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00823342 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT02503345 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study NCT00989586 — Biomarker: CD74 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD74; DHLAG
Study NCT00450463 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT04715750 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT02845518 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT02845518 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study NCT00757107 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03726463 — Biomarker: PRKD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKD1; PKD; PKD1; PRKCM
Study NCT03726463 — Biomarker: PKD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PKD2; TRPP2
Study NCT04020575 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study NCT00171782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02400203 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01318746 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study NCT02130700 — Biomarker: CYP17A1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CYP17A1; CYP17; S17AH
Study NCT02130700 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study NCT03645226 — Biomarker: Synuclein alpha
Type: Pharmacodynamic Biomarker (PDY)
Genes: SNCA; NACP; PARK1
Study NCT01749072 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01749072 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT02192775 — Biomarker: SLC5A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A5; NIS
Study NCT02186132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03676985 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03515785 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT03515785 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT02089828 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT05167292 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT02854683 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02685605 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study NCT03631329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04002323 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT03825042 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT00379483 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study NCT01871064 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT03918668 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT03918668 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study NCT03918668 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study NCT04449471 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study NCT02124109 — Biomarker: RHD mRNA
Type: Predictive Biomarker (PRD)
Genes: RHD
Study NCT01415960 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT00711503 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study NCT00154037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01767441 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT04083196 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT01449058 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study NCT01449058 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT01449058 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study NCT00867477 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study NCT04124718 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study NCT02006147 — Biomarker: DSP mRNA
Type: Predictive Biomarker (PRD)
Genes: DSP
Study NCT05696860 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00671047 — Biomarker: SAGE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAGE1; SAGE
Study NCT04500678 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04500678 — Biomarker: TIGIT mRNA
Type: Predictive Biomarker (PRD)
Genes: TIGIT; VSIG9; VSTM3
Study NCT04500678 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study NCT04500678 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04317196 — Biomarker: Survival motor neuron protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT03210285 — Biomarker: NF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF2; SCH
Study NCT01461473 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03841838 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03402048 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study NCT03402048 — Biomarker: Ribonucleoside-diphosphate reductase large subunit
Type: Predictive Biomarker (PRD)
Genes: RRM1; RR1
Study NCT03402048 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study NCT04103268 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT02513940 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study NCT00504582 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT03043365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02815033 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study NCT00095121 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT00057005 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study NCT00119483 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study NCT00367406 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT00146549 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02958410 — Biomarker: TNFRSF17 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF17; BCM; BCMA
Study NCT01646684 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study NCT00449059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03903055 — Biomarker: PAFAH1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA