AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24006239 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20555305 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10804025 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28537769 — Biomarker: KSR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KSR2
Study 21092958 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 17584667 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 10723506 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2616205 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30587963 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 19236695 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19236695 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9264500 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8405850 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12657339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1411317 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3516163 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31667693 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31667693 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28425497 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 19960134 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21303308 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 14666387 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 28410749 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15385016 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15385016 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8390528 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8390528 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24983306 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24983306 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 30943824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25540980 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 25540980 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18626487 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1425899 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10657576 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10657576 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 6706438 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 9258760 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29206136 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14759561 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11549203 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 16787138 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 28611089 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28611089 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10713626 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10713626 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 30221566 — Biomarker: SRGN mRNA
Type: Predictive Biomarker (PRD)
Genes: SRGN; PRG; PRG1
Study 30221566 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 22011557 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19284124 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6793373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23217036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10216808 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7797830 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26707295 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26707295 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 21813916 — Biomarker: MTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 28258090 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28258090 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15030266 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 1413136 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1413136 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 1413136 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18399897 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18399897 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7091898 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19523212 — Biomarker: GDA mRNA
Type: Predictive Biomarker (PRD)
Genes: GDA; KIAA1258
Study 15496697 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2848652 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2848652 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 18696157 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 28049190 — Biomarker: miR-146a
Type: Safety Biomarker (SAF)
Genes: MIR146A
Study 12777589 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3532756 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25255587 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25255587 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8546282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2468931 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 2468931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27397061 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25644328 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 7756706 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26822630 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30993400 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31532100 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 31532100 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25677713 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24004639 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24004639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24004639 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24004639 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11345386 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26480664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21682834 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11333290 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 7704288 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10340371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2523657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17485570 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 23193678 — Biomarker: CNBP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNBP; RNF163; ZNF9
Study 17567623 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 15205720 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15745109 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 15745109 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 11785558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2301245 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15257846 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2549243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25450993 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22455636 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 1756271 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 17122448 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 1810080 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30528802 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30528802 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 28198120 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28198120 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1654136 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29886354 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 29886354 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27920497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23682544 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 23682544 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17572410 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10572288 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 10572288 — Biomarker: CSF1R mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF1R; FMS
Study 2828458 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 2828458 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 26336931 — Biomarker: LRIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LRIT1; LRRC21; PAL
Study 2554244 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 28878181 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 19773666 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 18818679 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30556339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21544882 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15177812 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 12408210 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 28063795 — Biomarker: TSC2
Type: Predictive Biomarker (PRD)
Genes: tuberin; LAM; PPP1R160
Study 24358799 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 15947531 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9932938 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 7014694 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 27029919 — Biomarker: ATG7 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATG7; APG7L
Study 27029919 — Biomarker: CASP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CASP3; CPP32
Study 25822100 — Biomarker: PER1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PER1; KIAA0482; PER; RIGUI
Study 25822100 — Biomarker: PER2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PER2; KIAA0347
Study 25822100 — Biomarker: PER3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PER3; GIG13
Study 25822100 — Biomarker: TEF mRNA
Type: Predictive Biomarker (PRD)
Genes: TEF; KIAA1655
Study 25822100 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 25822100 — Biomarker: CD180 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD180; LY64; RP105
Study 25822100 — Biomarker: NFKBIA mRNA
Type: Predictive Biomarker (PRD)
Genes: NFKBIA; IKBA; MAD3; NFKBI
Study 25822100 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 25822100 — Biomarker: ACOX3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACOX3; BRCOX; PRCOX
Study 25822100 — Biomarker: IDH3A mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH3A
Study 21445638 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26608067 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26608067 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25559355 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 17717057 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26572168 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 26572168 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 26572168 — Biomarker: TFAM mRNA
Type: Predictive Biomarker (PRD)
Genes: TFAM; TCF6; TCF6L2
Study 6701249 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 29785045 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 26946725 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 23712600 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23712600 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21504975 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 7772369 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7772369 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2298969 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 31504587 — Biomarker: VIM mRNA
Type: Predictive Biomarker (PRD)
Genes: VIM
Study 20147572 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 10864908 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 10864908 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 10864908 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 10864908 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26748872 — Biomarker: ERCC2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MAG; EM9; MGC102762; MGC126218; MGC126219
Study 17911462 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 17911462 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17911462 — Biomarker: CXCR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR3; GPR9
Study 21198725 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12585985 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9035467 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9035467 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 27999852 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26289163 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16294574 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 11238259 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3685071 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 3685071 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 31038216 — Biomarker: SHH mRNA
Type: Predictive Biomarker (PRD)
Genes: SHH
Study 10382948 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10382948 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 29806538 — Biomarker: PRLR mRNA
Type: Predictive Biomarker (PRD)
Genes: PRLR
Study 26446239 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 26446239 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 26446239 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20847699 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10651671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29597198 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15848557 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12080961 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 29099680 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29099680 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29099680 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17536077 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6351901 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29355679 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 20142520 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16364826 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6802875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28171856 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21874537 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21874537 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17934877 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study 10611140 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 10611140 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 10611140 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 10611140 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 10611140 — Biomarker: CYP2E1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2E1; CYP2E
Study 9360003 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9360003 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22892123 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20980920 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 20980920 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 19526764 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19526764 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 8572869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30874378 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28579225 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10571341 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 1725891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31609422 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 24684838 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 24684838 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22669289 — Biomarker: FFAR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FFAR1; GPR40
Study 15851648 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22914998 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 22914998 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20837464 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20837464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17697909 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 7614647 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 7614647 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2517323 — Biomarker: SERPINF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINF2; AAP; PLI
Study 1013675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20579542 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20579542 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8956920 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 3294081 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP