AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 9064258 — Biomarker: PTPRC
Type: Predictive Biomarker (PRD)
Genes: LCA; T200; GP180
Study 9064258 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 9064258 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 22997787 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 17521315 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 17521315 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 18761816 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 18761816 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18761816 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12595863 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12595863 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1693042 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 23365108 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 19389471 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 19389471 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 27974055 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 23523116 — Biomarker: CCR2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCR2; CMKBR2
Study 2389649 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26912555 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 18852339 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18852339 — Biomarker: CD209 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD209; CLEC4L
Study 8973753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8973753 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 29037769 — Biomarker: DIAPH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DIAPH2; DIA
Study 22719060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20150526 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26121432 — Biomarker: Clusterin
Type: Safety Biomarker (SAF)
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 25270214 — Biomarker: BTLA mRNA
Type: Predictive Biomarker (PRD)
Genes: BTLA
Study 25270214 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 25270214 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25270214 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25270214 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25270214 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 2452997 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30830474 — Biomarker: miR-122
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR122
Study 30474426 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29761211 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 28780563 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 24565712 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 15345738 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 27678438 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27678438 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27678438 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21937526 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 21937526 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 15885167 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15885167 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15885167 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15885167 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2277475 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 396083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 396083 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 19661450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8013155 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 30758314 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 22999988 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 12689610 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 6754131 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18414202 — Biomarker: PNKP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNKP
Study 12493339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17026489 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15576973 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2646619 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30270543 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27720273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27720273 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27720273 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15492764 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 15492764 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 22834565 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 19278806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9329702 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 27169838 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20613459 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28000468 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23916935 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23916935 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6138939 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 6138939 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 6138939 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26164621 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 12645718 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12645718 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 11057406 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 8966497 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31208943 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 31208943 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 28753851 — Biomarker: CYP17A1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CYP17A1; CYP17; S17AH
Study 28753851 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 20218940 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12354129 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 12354129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12354129 — Biomarker: Urine free cortisol
Type: Surrogate Endpoint (SUR)
Study 15857327 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15857327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10847255 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6392119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22666496 — Biomarker: DNAJC5B mRNA
Type: Predictive Biomarker (PRD)
Genes: DNAJC5B; CSPBETA
Study 18508833 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15889132 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 17002927 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 10807748 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study 8285776 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22878749 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 12688625 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2407957 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31500588 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22552034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16325696 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 30949182 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30949182 — Biomarker: KLRK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRK1; D12S2489E; NKG2D
Study 30949182 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 30949182 — Biomarker: KLRC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRC2; NKG2C
Study 27119829 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9540144 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 8062609 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8062609 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 8062609 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8062609 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2643042 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31175814 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 25387489 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 23352954 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7824963 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 27012822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18728054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15243282 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31649376 — Biomarker: INHBA mRNA
Type: Predictive Biomarker (PRD)
Genes: INHBA
Study 31649376 — Biomarker: ACVR2B mRNA
Type: Predictive Biomarker (PRD)
Genes: ACVR2B
Study 31649376 — Biomarker: Angiopoietin-1
Type: Monitoring Biomarker (MOI)
Genes: ANGPT1; KIAA0003
Study 31649376 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 31649376 — Biomarker: GDF10 mRNA
Type: Predictive Biomarker (PRD)
Genes: GDF10; BMP3B
Study 31649376 — Biomarker: C-X-C motif chemokine 5
Type: Safety Biomarker (SAF)
Genes: CXCL5; ENA78; SCYB5
Study 31649376 — Biomarker: FGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF2; FGFB
Study 31649376 — Biomarker: FGF12 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF12; FGF12B; FHF1
Study 31649376 — Biomarker: OLR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OLR1; CLEC8A; LOX1
Study 31649376 — Biomarker: MMP13 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP13
Study 31649376 — Biomarker: IL23A mRNA
Type: Predictive Biomarker (PRD)
Genes: IL23A; SGRF; UNQ2498/PRO5798
Study 22056854 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17258146 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15059509 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 12042982 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 12042982 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25739031 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10676676 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16556241 — Biomarker: GDNF mRNA
Type: Predictive Biomarker (PRD)
Genes: GDNF
Study 14636820 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16995862 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9715184 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 6817772 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26628415 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 10023503 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 8522632 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2401129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2401129 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2401129 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31273763 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 10872310 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 30649227 — Biomarker: SCN9A mRNA
Type: Predictive Biomarker (PRD)
Genes: SCN9A; NENA
Study 25979609 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 22902348 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 10886311 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 10886311 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10886311 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 25234679 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 20573926 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 12942401 — Biomarker: NTS mRNA
Type: Predictive Biomarker (PRD)
Genes: NTS
Study 22222856 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 20212267 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18567749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16020596 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10471608 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19781902 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1970460 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7019558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14973794 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 11573665 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11573665 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28025025 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 3067546 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 3067546 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 29649795 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 29649795 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 23110951 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 20609183 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2259928 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 42529 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 17479444 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 17479444 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8018689 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9134445 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30049691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23254595 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18381567 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 17064600 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9922408 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2109658 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 11355932 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 11355932 — Biomarker: ABCC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC1; MRP; MRP1
Study 11355932 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 23914845 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 20950405 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20950405 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 20950405 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17645558 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17645558 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12800456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25909598 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 25909598 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25909598 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25909598 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25132158 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 7801861 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 378733 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20580216 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17854302 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 7117166 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18024668 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 18024668 — Biomarker: CHM mRNA
Type: Predictive Biomarker (PRD)
Genes: CHM; REP1; TCD
Study 20627022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31464392 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 25249397 — Biomarker: CXCL13 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL13; BCA1; BLC; SCYB13
Study 25249397 — Biomarker: CXCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR5; BLR1; MDR15
Study 18003959 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18003959 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8260695 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29972516 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22722637 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20842051 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20842051 — Biomarker: TLR9
Type: Predictive Biomarker (PRD)
Genes: CD289
Study 2378793 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 23206440 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 23206440 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 23206440 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 18722681 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 18722681 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 18722681 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 15766446 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14625173 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9026373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1791622 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1791622 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 1791622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6136793 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15765306 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12394652 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 31498127 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 29496007 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26963434 — Biomarker: BAD mRNA
Type: Predictive Biomarker (PRD)
Genes: BAD; BBC6; BCL2L8