AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 6185343 — Biomarker: BLM mRNA
Type: Predictive Biomarker (PRD)
Genes: BLM; RECQ2; RECQL3
Study 25074351 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8704691 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25029202 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20385996 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 10197295 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 7551881 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 7551881 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 31618905 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31618905 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 31618905 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30967424 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 30967424 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29499873 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17344605 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 9756307 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 3048053 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3048053 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30246187 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 12704348 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 8807660 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 31999489 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29669604 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 23788750 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23788750 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 16769264 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 9425363 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12854090 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12854090 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 1725444 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28177460 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28177460 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 22607698 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 12381339 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21252728 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31657614 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18670365 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16002796 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16002796 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 8557785 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 1954079 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 6751166 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 23962028 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23962028 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 10737482 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30670251 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27827397 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23312562 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 23312562 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 7702230 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7702230 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12559241 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 29735021 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20619382 — Biomarker: CD81 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD81; TAPA1; TSPAN28
Study 12708964 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 6978687 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 29893003 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 1913714 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29373687 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16572737 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 31036412 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31036412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19914604 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 21095620 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21095620 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8804929 — Biomarker: TAC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAC1; NKA; NKNA; TAC2
Study 6368960 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 23535332 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9297313 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9297313 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9297313 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31488492 — Biomarker: SQSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SQSTM1; ORCA; OSIL
Study 28817434 — Biomarker: PTMS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTMS
Study 24144899 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2447516 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 2447516 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15809365 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 1683250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22204725 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 29231339 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26551272 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21555684 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 10901185 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 18558026 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9301443 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9301443 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9301443 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 24397879 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 22422589 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 18672531 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1503287 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27792720 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17586424 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28785809 — Biomarker: miR-155
Type: Safety Biomarker (SAF)
Genes: MIR155
Study 28785809 — Biomarker: miR-223
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR223
Study 28785809 — Biomarker: miR-181a
Type: Safety Biomarker (SAF)
Study 28785809 — Biomarker: miR-146a
Type: Safety Biomarker (SAF)
Genes: MIR146A
Study 19175712 — Biomarker: Argininosuccinate synthase
Type: Safety Biomarker (SAF)
Genes: ASS1; ASS
Study 10393617 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31382005 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 15870641 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15870641 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 12000487 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 2487533 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2487533 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 648206 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31788828 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 24084214 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24084214 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24084214 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18197403 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 18197403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28793919 — Biomarker: ID1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ID1; BHLHB24; ID
Study 24016502 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 21099666 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18236463 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 15265847 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9280211 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10967150 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1437342 — Biomarker: PRPH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRPH2; PRPH; RDS; TSPAN22
Study 3885671 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 29738817 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 28033320 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17283177 — Biomarker: APEX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 17283177 — Biomarker: PARP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PARP1; ADPRT; PPOL
Study 11465585 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7878692 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 29643011 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28858440 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 25851628 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25851628 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 25851628 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 25851628 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 25851628 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 21446378 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 21446378 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 8587426 — Biomarker: EDNRA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDNRA; ETA; ETRA
Study 8587426 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 20526759 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 15683753 — Biomarker: ADRA2C mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRA2C; ADRA2L2; ADRA2RL2
Study 12854503 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 1682683 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24374068 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17852017 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 12351591 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9690802 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 21810897 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 21810897 — Biomarker: AGTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study 21810897 — Biomarker: AGTR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AGTR2
Study 21810897 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3100910 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30582156 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 22446297 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 17610900 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1724390 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 24714660 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31641887 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24807156 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24807156 — Biomarker: NRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRP1; NRP; VEGF165R
Study 24807156 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24807156 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 20195952 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20195952 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20195952 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 17263884 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 17263884 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1752914 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 6810204 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 28281736 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 3107374 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 25525163 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 25525163 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16137195 — Biomarker: XRCC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: XRCC3
Study 24132814 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19330493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27653813 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 27653813 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24065259 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 15220015 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11558859 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11558859 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11558859 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23617089 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 9365092 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9365092 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9365092 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24946635 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 9449392 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7653442 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31307434 — Biomarker: STUB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STUB1; CHIP; PP1131
Study 24664189 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23318311 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 3732093 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26716656 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 24574351 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25986159 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25509258 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22287641 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 18257772 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1737543 — Biomarker: TNFRSF10A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 30244844 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18835953 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17786067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14638340 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 31064361 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19430350 — Biomarker: FBN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBN1; FBN
Study 16963731 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24357853 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10478142 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 10478142 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1917320 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31892336 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31892336 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31892336 — Biomarker: PERP mRNA
Type: Predictive Biomarker (PRD)
Genes: PERP; KCP1; KRTCAP1; PIGPC1; THW
Study 31892336 — Biomarker: YWHAQ mRNA
Type: Predictive Biomarker (PRD)
Genes: YWHAQ
Study 31892336 — Biomarker: SAP130 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAP130
Study 31892336 — Biomarker: HDAC4 mRNA
Type: Predictive Biomarker (PRD)
Genes: HDAC4; KIAA0288
Study 31892336 — Biomarker: NCOA7 mRNA
Type: Predictive Biomarker (PRD)
Genes: NCOA7; ERAP140; ESNA1; Nbla00052; Nbla10993
Study 31892336 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 31892336 — Biomarker: GDNF mRNA
Type: Predictive Biomarker (PRD)
Genes: GDNF
Study 31892336 — Biomarker: STAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT1
Study 31892336 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 19365873 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 2492893 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 2492893 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 4851464 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 23341486 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21697540 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 29567956 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 2359302 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 26787505 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22437139 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 7720336 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 8636520 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 27764781 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 27764781 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 3917702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23059790 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 22093120 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26359996 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 30287610 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27052961 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16699827 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24943000 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23031516 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 23031516 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1