AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 11219479 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11219479 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11219479 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9475657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2739019 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26297360 — Biomarker: RAPGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 21324150 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2421751 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17923401 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 17923401 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17923401 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 17923401 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 2170885 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2170885 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 2170885 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31365280 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 25785441 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25785441 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25785441 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8389662 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 29876844 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 29876844 — Biomarker: SLC35A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC35A2; UGALT; UGT; UGTL
Study 18974717 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 10596684 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 8537687 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30626285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2138237 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 22476616 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 25694056 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 25694056 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19444561 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 17314338 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11438316 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 21813807 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 21813807 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16679630 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16679630 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28391756 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23643011 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25932792 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 16861099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12963170 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11041396 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 19717399 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30919249 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30919249 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27420976 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27420976 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 27420976 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 27420976 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7718316 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 6345013 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 30628088 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 22969203 — Biomarker: MOXD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MOXD1; MOX; UNQ2493/PRO5780
Study 19118805 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 2644533 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31418411 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7844226 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3142396 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3142396 — Biomarker: LAT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAT2; LAB; NTAL; WBS15; WBSCR15; WBSCR5; HSPC046
Study 9803988 — Biomarker: BLVRA mRNA
Type: Predictive Biomarker (PRD)
Genes: BLVRA; BLVR; BVR
Study 9803988 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 15010066 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9683329 — Biomarker: TEF mRNA
Type: Predictive Biomarker (PRD)
Genes: TEF; KIAA1655
Study 7885940 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 30908574 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 30908574 — Biomarker: UGT2B15 mRNA
Type: Predictive Biomarker (PRD)
Genes: UGT2B15; UGT2B8
Study 30908574 — Biomarker: SULT1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SULT1A1; STP; STP1; OK/SW-cl.88
Study 15806975 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15806975 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15806975 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 15806975 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 21102344 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 16569797 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 1551152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18478253 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 1646240 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1646240 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12823907 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 10753983 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10753983 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10753983 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 30813694 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 18405788 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 15888152 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24812899 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24812899 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 15125006 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11379380 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 30904595 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30904595 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30022334 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26174879 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22748590 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 22748590 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19890256 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study 16050054 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 16050054 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16050054 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14624217 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 14624217 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 1732652 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1732652 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23823716 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23823716 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20018913 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18627001 — Biomarker: TBP mRNA
Type: Predictive Biomarker (PRD)
Genes: TBP; GTF2D1; TF2D; TFIID
Study 12162932 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7326269 — Biomarker: LSS mRNA
Type: Predictive Biomarker (PRD)
Genes: LSS; OSC
Study 11673752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30954071 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 21938889 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 10585174 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 2053167 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31578205 — Biomarker: TET2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET2; KIAA1546; Nbla00191
Study 31578205 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 31578205 — Biomarker: ZRSR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZRSR2; U2AF1-RS2; U2AF1L2; U2AF1RS2; URP
Study 18235123 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study 1846723 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31925799 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31925799 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11850709 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26539650 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26539650 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11144434 — Biomarker: CFB mRNA
Type: Predictive Biomarker (PRD)
Genes: CFB; BF; BFD
Study 26197707 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12850126 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 25194505 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 20822027 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20822027 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 7571220 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7571220 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2076734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28538380 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 28538380 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23457307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21879181 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19453516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8384187 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30885221 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30885221 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30885221 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30885221 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17917927 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 11848168 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2298472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30981681 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30981681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27994300 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27994300 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22726916 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 16575135 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 10194656 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6763175 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 28183140 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 28183140 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 23337728 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21266948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21266948 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15322457 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8164925 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3211806 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 3211806 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 31430623 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 18768332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25429853 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 25429853 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30027669 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 26336919 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26336919 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 26336919 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 26336919 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 24252587 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 29523800 — Biomarker: TREM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TREM2
Study 26209090 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 22961907 — Biomarker: MMD mRNA
Type: Predictive Biomarker (PRD)
Genes: MMD; PAQR11
Study 22961907 — Biomarker: CCR2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCR2; CMKBR2
Study 22961907 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27729394 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23989522 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 26153128 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23759268 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23759268 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25249429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24660233 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 24660233 — Biomarker: Nasal potential difference
Type: Pharmacodynamic Biomarker (PDY)
Study 7843446 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 2646004 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 2646004 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 22315776 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19919399 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19712802 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 17961387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21219394 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 15657568 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 2878680 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2878680 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31594394 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31594394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29053185 — Biomarker: MLH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MLH1; COCA2
Study 17692951 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16815780 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11594525 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 11594525 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8466377 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24980650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31678307 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 21562068 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21562068 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15508793 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 11557163 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 11557163 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 26269563 — Biomarker: AMPH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMPH; AMPH1
Study 26269563 — Biomarker: CDKN2A mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2A; CDKN2; MTS1
Study 26269563 — Biomarker: Epithelial cadherin
Type: Predictive Biomarker (PRD)
Genes: CDH1; CDHE; UVO
Study 26269563 — Biomarker: EN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EN1
Study 26269563 — Biomarker: EMX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EMX1
Study 26269563 — Biomarker: PCDH10 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCDH10; KIAA1400
Study 26269563 — Biomarker: RPRM mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: RPRM
Study 26269563 — Biomarker: RSPO2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RSPO2; UNQ9384/PRO34209
Study 26269563 — Biomarker: SORCS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SORCS3; KIAA1059
Study 26269563 — Biomarker: ZIC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZIC1; ZIC; ZNF201
Study 26269563 — Biomarker: ZNF610 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZNF610
Study 21511222 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 2459525 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11320947 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 19854632 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 16118573 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16118573 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 27080343 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 27080343 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 27080343 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 27080343 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 27080343 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 27080343 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 27080343 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 24622750 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 19029269 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 10357338 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8546442 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 1672870 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH