AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 8786722 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 2276384 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22805324 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 15567174 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15567174 — Biomarker: GATA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GATA3
Study 15567174 — Biomarker: AGR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AGR2; AG2; UNQ515/PRO1030
Study 15567174 — Biomarker: Phospholipase A2 inhibitory protein
Type: Predictive Biomarker (PRD)
Genes: ANXA1; ANX1; LPC1
Study 10446819 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10246462 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1798005 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6358278 — Biomarker: MMD mRNA
Type: Predictive Biomarker (PRD)
Genes: MMD; PAQR11
Study 31601583 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 27402064 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 25015689 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22230419 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 19076192 — Biomarker: GLS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS2; GA
Study 9746115 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 17364275 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28091703 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15189478 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15189478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9501680 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 18218206 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 21962261 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 21962261 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21962261 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21962261 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27578117 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 338206 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 22147649 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 31072180 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 31072180 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 31072180 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 31072180 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17463075 — Biomarker: GSS mRNA
Type: Predictive Biomarker (PRD)
Genes: GSS
Study 15465747 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9551703 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 9551703 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9551703 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7059257 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24509134 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24509134 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24509134 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20378381 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10234600 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 9193325 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24284272 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 15662234 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15662234 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 1835292 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 1835292 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31377160 — Biomarker: ESR1
Type: Predictive Biomarker (PRD)
Genes: NR3A1; Era; ER-alpha
Study 31377160 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31377160 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 21343393 — Biomarker: TLR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR3
Study 9568453 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26690312 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 1877740 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 25251443 — Biomarker: SOX11 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOX11
Study 25251443 — Biomarker: Nuclear factor erythroid 2-related factor 2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: NFE2L2; NRF2
Study 25251443 — Biomarker: SMAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMAD1; BSP1; MADH1; MADR1
Study 25251443 — Biomarker: Mothers against decapentaplegic homolog 2
Type: Predictive Biomarker (PRD)
Genes: SMAD2; MADH2; MADR2
Study 25251443 — Biomarker: SMAD3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMAD3; MADH3
Study 25251443 — Biomarker: SMAD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMAD4; DPC4; MADH4
Study 23353608 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9726802 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9726802 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 2568072 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21607703 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19759043 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17726314 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17726314 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 17726314 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7995386 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 7995386 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 2457768 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2457768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17880017 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 9794348 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25430415 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 9360208 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9360208 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20692140 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 18797738 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 8622245 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8622245 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8622245 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8622245 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30466402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22759406 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 22490901 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 22490901 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24748629 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 23378102 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 19661449 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10785875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29325799 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11114683 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28289041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23339731 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19018783 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study 14643577 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31280343 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 26819195 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26819195 — Biomarker: APOB mRNA
Type: Predictive Biomarker (PRD)
Genes: APOB
Study 21569370 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 19236277 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 16449396 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9184262 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9184262 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30354330 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 30354330 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26630992 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 14604244 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 9186303 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 9186303 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 25725625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23551710 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23551710 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 21775166 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21775166 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21775166 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10770306 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9293310 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9293310 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8223838 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28697803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8932874 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8932874 — Biomarker: ESR1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ESR1; ESR; NR3A1
Study 30788944 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18269820 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 1722310 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 31426864 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 26334096 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 20070721 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 17317391 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 17317391 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17317391 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9362390 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 1318845 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1318845 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 1318845 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 18305461 — Biomarker: ADORA2A mRNA
Type: Predictive Biomarker (PRD)
Genes: ADORA2A; ADORA2
Study 18305461 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 3904394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25367242 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18851750 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9190239 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1283426 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1283426 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28135975 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28135975 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28135975 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28135975 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19022694 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study 15300183 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11372667 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 11372667 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19888533 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 19888533 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 30515674 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30515674 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23046593 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 12730532 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2833090 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2833090 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2833090 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 2833090 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 26335224 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 24005315 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 12750540 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 30998125 — Biomarker: FAU mRNA
Type: Predictive Biomarker (PRD)
Genes: FAU
Study 24152823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18341178 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 28133925 — Biomarker: GCA mRNA
Type: Predictive Biomarker (PRD)
Genes: GCA; GCL
Study 19210151 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20352546 — Biomarker: CENPJ mRNA
Type: Predictive Biomarker (PRD)
Genes: CENPJ; CPAP; LAP; LIP1
Study 30540568 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 27490915 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18628422 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29783024 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 9704685 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28838379 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 21811833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17467954 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12482109 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12482109 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30668137 — Biomarker: CFI mRNA
Type: Predictive Biomarker (PRD)
Genes: CFI; IF
Study 28138315 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 23741991 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23741991 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study 23741991 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23741991 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 19172543 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 27021556 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27021556 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27021556 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18443125 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 18443125 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 25987260 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24282774 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15006009 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 22978405 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 19192440 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 10698231 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8232766 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8232766 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 28161697 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25850966 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 22721608 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 22721608 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 19167999 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 16966852 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31166987 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31166987 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31166987 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 26567961 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15987536 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9475275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19920000 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16753973 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 9990360 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 3056057 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 3056057 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26647154 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18712575 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 2178930 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29081307 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 29081307 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 25366684 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 17485023 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17485023 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7669316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27565129 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21192153 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17206296 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1980201 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31797035 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27543440 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 27543440 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 2883214 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26466857 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 26466857 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 8172793 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 2963523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20298418 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)