AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 24749639 — Biomarker: OXTR mRNA
Type: Predictive Biomarker (PRD)
Genes: OXTR
Study 24469880 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24469880 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 24469880 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24886034 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 30454883 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20713883 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9396450 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2452123 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 2452123 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23148280 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11214135 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 30989339 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27631248 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 27631248 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18281662 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 29447787 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 24195609 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24195609 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24195609 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11397720 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 11397720 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 2967187 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28329231 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 28329231 — Biomarker: STAT5A mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT5A; STAT5
Study 28571235 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28571235 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15246889 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15246889 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15246889 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 15246889 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11189397 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 1971028 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8820893 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 8820893 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25179086 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17578790 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9734748 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 29993297 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 24008606 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 14758573 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11812703 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31745762 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31745762 — Biomarker: MMP10 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MMP10; STMY2
Study 31745762 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 31745762 — Biomarker: IL13RA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL13RA2; IL13R
Study 31745762 — Biomarker: ZCCHC12 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZCCHC12; SIZN1
Study 31745762 — Biomarker: SRARP mRNA
Type: Predictive Biomarker (PRD)
Genes: SRARP; C1orf64; ERRF; SSPR
Study 28192673 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26317257 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22025580 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16832022 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 25245113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25245113 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23863908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21779579 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8324040 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 27483458 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15173671 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 25938633 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 25938633 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15202379 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31075364 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 20023571 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23239675 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15373937 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 10949098 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12653258 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 16862245 — Biomarker: CPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPZ
Study 16862245 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 27655646 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26908330 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 26908330 — Biomarker: CSF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF1
Study 26908330 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 26908330 — Biomarker: Hepatitis A virus cellular receptor 1
Type: Safety Biomarker (SAF)
Genes: HAVCR1; KIM1; TIM1; TIMD1
Study 29156488 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 25096769 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7915916 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 31517663 — Biomarker: CFL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CFL1; CFL
Study 26698263 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26698263 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26698263 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 1571340 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2856757 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25311218 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 18547825 — Biomarker: A1CF mRNA
Type: Predictive Biomarker (PRD)
Genes: A1CF; ACF; ASP
Study 18547825 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7560489 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 28425772 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28425772 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 29677060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23903371 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 23903371 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 23903371 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 22171015 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2884859 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2884859 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31813662 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 30006861 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 28493376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16805678 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 8399091 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8399091 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23032322 — Biomarker: HHEX mRNA
Type: Predictive Biomarker (PRD)
Genes: HHEX; HEX; PRH; PRHX
Study 18490845 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2048560 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 7665996 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28002447 — Biomarker: HTR3A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR3A; 5HT3R; HTR3
Study 20044242 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 27898183 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 31302234 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 31302234 — Biomarker: CCND1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND1; BCL1; PRAD1
Study 31302234 — Biomarker: CCND2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND2
Study 31302234 — Biomarker: CCND3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND3
Study 31302234 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 23978944 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 17207028 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15311830 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 2636644 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 2636644 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2636644 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21522097 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20137491 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 16885180 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9060793 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10559513 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8698011 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19017314 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24321374 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 8791276 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8791276 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16416643 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 12601486 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 10509569 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8984939 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11264639 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 18760137 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18760137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12766934 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1683422 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 19863450 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 19151458 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11388472 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 11388472 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31088176 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19332969 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11197756 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7871035 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 3250315 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 3250315 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30287671 — Biomarker: HNF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: HNF1A; TCF1
Study 30287671 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 31396815 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23435032 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 21912122 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21912122 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 21912122 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 21912122 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 21912122 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19052054 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 19052054 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 14980929 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8148356 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8148356 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 30655509 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 16961773 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9109860 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9109860 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9109860 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8258118 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30064301 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 10178659 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8157786 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 21640689 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16816554 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1919633 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1919633 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 6925851 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31441409 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 26645521 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26645521 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26645521 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26645521 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23178539 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 21465247 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 28315922 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 21122658 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10561318 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 29655624 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17387129 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 17387129 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17387129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11694947 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11720426 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 9219909 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8238379 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22305809 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 22305809 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18807007 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 18807007 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 18807007 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14607210 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14607210 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19262464 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 16138563 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31435005 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26074314 — Biomarker: Hypoxia-inducible factor 1-alpha
Type: Predictive Biomarker (PRD)
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 7663574 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 30656889 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10877165 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 7692166 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3549869 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 31015198 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 29486131 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22001664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9466024 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22949583 — Biomarker: ANKK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANKK1; PKK2; SGK288
Study 20580572 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 18167121 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 18167121 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12623165 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12623165 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 29368537 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 22840917 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16612708 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 16612708 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26113439 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 26113439 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 11309019 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3031150 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3031150 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18568324 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 18568324 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15768198 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22241898 — Biomarker: CDKN1B mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN1B; KIP1; p27
Study 17392721 — Biomarker: REEP5 mRNA
Type: Predictive Biomarker (PRD)
Genes: REEP5; C5orf18; DP1; TB2
Study 10067815 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 7564362 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7564362 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 29956019 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28596274 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15766363 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA