AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 12167115 — Biomarker: USP9X mRNA
Type: Predictive Biomarker (PRD)
Genes: USP9X; DFFRX; FAM; USP9
Study 1905438 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27528065 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27528065 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 2105087 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 31376501 — Biomarker: P4HB mRNA
Type: Predictive Biomarker (PRD)
Genes: P4HB; ERBA2L; PDI; PDIA1; PO4DB
Study 21439754 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21439754 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11402115 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 7818046 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31334544 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 23475103 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14685799 — Biomarker: ABCG5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG5
Study 14685799 — Biomarker: ABCG8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCG8
Study 14685799 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2850807 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 2850807 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 2850807 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31859172 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8809428 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8338403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26875428 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23541564 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23541564 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 15915277 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22434018 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study 18534138 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 2736876 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31782814 — Biomarker: MNT mRNA
Type: Predictive Biomarker (PRD)
Genes: MNT; BHLHD3; ROX
Study 31782814 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 21700922 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 18208636 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 18208636 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 12972982 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 12716087 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10232739 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 6122111 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30288819 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 24562449 — Biomarker: SPARC mRNA
Type: Predictive Biomarker (PRD)
Genes: SPARC; ON
Study 22209386 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7522282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7522282 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3439796 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 20338811 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20338811 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 7617607 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7617607 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2520143 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2520143 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 405412 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 24209829 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15149420 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 17684203 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 18408393 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 18408393 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10590497 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 10590497 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10999838 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10999838 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10999838 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8448068 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27009022 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 27009022 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 8782752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28988172 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12850192 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 1473919 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 1473919 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 27120329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17662528 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 17662528 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 11468025 — Biomarker: SKAP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R
Study 11468025 — Biomarker: CTRC mRNA
Type: Predictive Biomarker (PRD)
Genes: CTRC; CLCR
Study 11468025 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24279445 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 21167338 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 31974286 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 31547827 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 25712944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9440666 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 2547916 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28125624 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25601978 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19336728 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 19336728 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 7630982 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31524770 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15472858 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17393216 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17393216 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31270173 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 1519166 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21338187 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 10958222 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8474315 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25038306 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25038306 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25038306 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23226979 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15551351 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 12046308 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 7878390 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 22117659 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 22117659 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 16775813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3147905 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 3147905 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 25318481 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 21592879 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17030755 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 10857171 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 3006619 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31506396 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 15056426 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 11703993 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22672229 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 21719896 — Biomarker: TRPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPA1; ANKTM1
Study 30465917 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 30465917 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 19124484 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19124484 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 15482085 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 3033444 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3033444 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18580254 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study 7720912 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 2116441 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 25091659 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 10757465 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10757465 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1009279 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28085793 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28085793 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 25990454 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25990454 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10490157 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31332027 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15071723 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31228203 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26272871 — Biomarker: PNPLA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PNPLA3; ADPN; C22orf20
Study 26272871 — Biomarker: TM6SF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TM6SF2
Study 15638973 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 18390891 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18390891 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 21843712 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21843712 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 24453130 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21049601 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 17382027 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17382027 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11641299 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 31397943 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 12393737 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 20935337 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18405787 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18405787 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 9661633 — Biomarker: SLC5A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A5; NIS
Study 9661633 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 29162361 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 26859828 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17319797 — Biomarker: CPT1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CPT1A; CPT1
Study 9661544 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2577460 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31823063 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 30701400 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 17606328 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 12122965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17609908 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 17609908 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 17609908 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27741007 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 17046377 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12894131 — Biomarker: CD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD2; SRBC
Study 29431561 — Biomarker: SMPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMPD1; ASM
Study 26826274 — Biomarker: SAGE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAGE1; SAGE
Study 20634296 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 20634296 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12807386 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 11137977 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17890954 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 14981602 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14981602 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8138680 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25216712 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25216712 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2485043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20051299 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 20051299 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 10094243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31067706 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 30935897 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28829155 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 27348483 — Biomarker: IFNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 25102686 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 15786529 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 17352284 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29794306 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 19088352 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9764631 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9764631 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 7919326 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7919326 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3277494 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31914324 — Biomarker: ADRA1D mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRA1D; ADRA1A
Study 23412015 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24660272 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 11136787 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11136787 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 2563311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2563311 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2563311 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23065000 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 23065000 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 19967563 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 12601621 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8875514 — Biomarker: Glutamate dehydrogenase
Type: Safety Biomarker (SAF)
Study 1720487 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23354927 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18419878 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16965691 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 16965691 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12856155 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 1328365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1328365 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 24607553 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20206356 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20206356 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18596318 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18596318 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 9431859 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22134839 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 22134839 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 31571445 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 28255099 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 9247941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2881481 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19924670 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 16380544 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 21263058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11895966 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 7872318 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 2205161 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 20601671 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29092879 — Biomarker: DMA mRNA
Type: Predictive Biomarker (PRD)
Genes: DMA; HLA-DMA; hCG_2001572
Study 25164513 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)