AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 8027275 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 26580673 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21068341 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 9500558 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 2565687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28918754 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 28918754 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28918754 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 25038558 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7917532 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 7917532 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 7917532 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 19769477 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16784179 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16784179 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23425564 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 23425564 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 17465257 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 27882820 — Biomarker: AXL mRNA
Type: Predictive Biomarker (PRD)
Genes: AXL; UFO
Study 27882820 — Biomarker: DCT mRNA
Type: Predictive Biomarker (PRD)
Genes: DCT; TYRP2
Study 24386809 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24386809 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 21481871 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 21481871 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 21481871 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21481871 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 21481871 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 19190265 — Biomarker: Insulin receptor substrate 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IRS1
Study 25223844 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 23887901 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16248380 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 8259772 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29885375 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 28177189 — Biomarker: G0S2 mRNA
Type: Predictive Biomarker (PRD)
Genes: G0S2
Study 15960556 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30406819 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22927115 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 19534294 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 14760320 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14760320 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9549270 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2656774 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21413940 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19188680 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12575547 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 1703327 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 17922461 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 17922461 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 16135353 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12161491 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10434215 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23554029 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23554029 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17967583 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 7622850 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22589376 — Biomarker: CCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR1; CMKBR1; CMKR1; SCYAR1
Study 22589376 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11391320 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 9578521 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 7526056 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29321134 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29321134 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22731679 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 22731679 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19795993 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18378030 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 10525492 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 1013693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28582885 — Biomarker: PNMA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PNMA2; KIAA0883; MA2
Study 21592370 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 11338763 — Biomarker: INPP5D mRNA
Type: Predictive Biomarker (PRD)
Genes: INPP5D; SHIP; SHIP1
Study 9212125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31780201 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31780201 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 14691426 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14691426 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 14691426 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8310991 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3337484 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 27569003 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 26677669 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1323926 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 6507905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6507905 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20939113 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20939113 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20939113 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10372241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31928474 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24154863 — Biomarker: RNH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RNH1; PRI; RNH
Study 24154863 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 20854964 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30540701 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 22248750 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 16336059 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16336059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11887131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2195704 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 26887213 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 23359185 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 22097348 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30115007 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 21087499 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 14501856 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8794438 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8794438 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 31157663 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24675102 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17919549 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1771968 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 29986268 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 28427456 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 14613435 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21699953 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21699953 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10959482 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 1284331 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 17925417 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 8794822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1310464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21570271 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19634546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10856732 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29027352 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25702786 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 25702786 — Biomarker: DHCR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: DHCR7; D7SR
Study 25702786 — Biomarker: CYP2R1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2R1
Study 25702786 — Biomarker: CYP24A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP24A1; CYP24
Study 24737923 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12584671 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12584671 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1975189 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1975189 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28374907 — Biomarker: NF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF2; SCH
Study 17804673 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12667363 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 12667363 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12667363 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 7818118 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7818118 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28446631 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28446631 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 6084754 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 6084754 — Biomarker: TMEM37 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMEM37; PR
Study 26654244 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20820148 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 17085378 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17085378 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10805047 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30613964 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16271337 — Biomarker: FBL mRNA
Type: Predictive Biomarker (PRD)
Genes: FBL; FIB1; FLRN
Study 20393508 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 19673331 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 16840747 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11273875 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 3057832 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30883000 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7838921 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3414514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16360267 — Biomarker: PAG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAG1; CBP; PAG
Study 8937798 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 17916662 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 17916662 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8619011 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 29131124 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 21248398 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 10731735 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30582447 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 23356124 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22042366 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22042366 — Biomarker: TOP2A mRNA
Type: Predictive Biomarker (PRD)
Genes: TOP2A; TOP2
Study 20381283 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 20381283 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 18060244 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 12766123 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 29551346 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 24509697 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28011809 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24961753 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 24961753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21983371 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21983371 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21983371 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19578220 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11314833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28228162 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 28228162 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 21068346 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28810 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31542876 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 26103654 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 15138475 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 17339189 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 17339189 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 11295361 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 25935793 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25935793 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16337368 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 19118910 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17727860 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14646367 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14646367 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25306677 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25306677 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25306677 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 25306677 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 24748338 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23735004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23735004 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23735004 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17133193 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9024265 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30712954 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 20972900 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17950795 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17242663 — Biomarker: Chromosome 5q
Type: Predictive Biomarker (PRD)
Study 10804778 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30898204 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 30898204 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 1418836 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30004900 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26976418 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 16359503 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16359503 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9551874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29311763 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30415610 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30415610 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25900168 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 25900168 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25900168 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 21450597 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 11960657 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 28199814 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 28199814 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 28199814 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2