AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 21649590 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21649590 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21649590 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 19347385 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3773141 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3773141 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26288364 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12174030 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12174030 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7843746 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25844322 — Biomarker: CA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA3
Study 1671380 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29071873 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 24512909 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20976257 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15787665 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1672488 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29021285 — Biomarker: LRP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LRP2
Study 29021285 — Biomarker: CUBN mRNA
Type: Predictive Biomarker (PRD)
Genes: CUBN; IFCR
Study 29021285 — Biomarker: CYP2R1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2R1
Study 29021285 — Biomarker: CYP24A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP24A1; CYP24
Study 29021285 — Biomarker: CYP27B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 23591659 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 23591659 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 7990020 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 12825305 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31096309 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 19204218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17381533 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 8090456 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 2682023 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2682023 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 29117238 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 29117238 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24476776 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24476776 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 31801993 — Biomarker: FMN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMN1; FMN; LD
Study 25197025 — Biomarker: GCGR mRNA
Type: Predictive Biomarker (PRD)
Genes: GCGR
Study 21957896 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9354525 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 27144545 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 27144545 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20538698 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18795588 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8599316 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18946061 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 31003911 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 15088127 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15088127 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11418230 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 30814028 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16441475 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 12940870 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8885206 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1396619 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1396619 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27173785 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 27173785 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 27173785 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 18441454 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18441454 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10973391 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1620908 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 26614144 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 17119520 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11510804 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11510804 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 9764780 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3296353 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23799692 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 22248893 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10834773 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 8226001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24976224 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22313793 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10696629 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24891337 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 21276681 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8343321 — Biomarker: DCC mRNA
Type: Predictive Biomarker (PRD)
Genes: DCC; IGDCC1
Study 14717059 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 1325772 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 31600368 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31600368 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24758565 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 24758565 — Biomarker: THBS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: THBS1; TSP; TSP1
Study 24758565 — Biomarker: TLR9
Type: Predictive Biomarker (PRD)
Genes: CD289
Study 17875241 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 16076378 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 10573104 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31923303 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 29608336 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 19083105 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15506067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10865218 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23834545 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 27161257 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24878421 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 23107220 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 24035168 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 24035168 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16644439 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 12553385 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 7767541 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 25476074 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22030597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12219873 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 973982 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30285186 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 28675091 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2921100 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2921100 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 19483074 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29509929 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 23418154 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 18376181 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 14585524 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 14585524 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27460108 — Biomarker: CHM mRNA
Type: Predictive Biomarker (PRD)
Genes: CHM; REP1; TCD
Study 15695500 — Biomarker: FMOD mRNA
Type: Predictive Biomarker (PRD)
Genes: FMOD; FM; SLRR2E
Study 23653274 — Biomarker: RAB8A mRNA
Type: Predictive Biomarker (PRD)
Genes: RAB8A; MEL; RAB8
Study 20046574 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 20046574 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17287448 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 3359658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27219520 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24942611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16995860 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10750566 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9363656 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 29921800 — Biomarker: ADCY3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADCY3; KIAA0511
Study 30529477 — Biomarker: FOXO3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXO3; FKHRL1; FOXO3A
Study 17668881 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 17668881 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7907871 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31340800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25147236 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19689480 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 22237735 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19719746 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9535143 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2551565 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2551565 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23211558 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 19592054 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 19592054 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19592054 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 11913478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26571184 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24134424 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 20090562 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16380824 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 15538040 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15538040 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 15538040 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15538040 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15538040 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18487998 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 18487998 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 11485281 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17714844 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31967673 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30657852 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28081369 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31394939 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20383874 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28301292 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25062900 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 25062900 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 21994354 — Biomarker: LTB mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB; TNFC; TNFSF3
Study 21994354 — Biomarker: CLSTN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLSTN3; CS3; KIAA0726
Study 30922017 — Biomarker: SHB mRNA
Type: Predictive Biomarker (PRD)
Genes: SHB
Study 25618418 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25618418 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25618418 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 25209550 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25209550 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20078871 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8681312 — Biomarker: CNTF mRNA
Type: Predictive Biomarker (PRD)
Genes: CNTF
Study 8681312 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31082512 — Biomarker: CHM mRNA
Type: Predictive Biomarker (PRD)
Genes: CHM; REP1; TCD
Study 20807094 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 20807094 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 17984165 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 17984165 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17984165 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17984165 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17984165 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 17984165 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 10495176 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8543208 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1961959 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31737175 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31737175 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 31737175 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 26019129 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 24754047 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 24754047 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20854735 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20854735 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 20854735 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20854735 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29660207 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study 20416130 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8382753 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28750917 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 22448738 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 792688 — Biomarker: Complement C4
Type: Monitoring Biomarker (MOI)
Study 24624380 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 21390543 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 19131891 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11430936 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9601653 — Biomarker: CNTF mRNA
Type: Predictive Biomarker (PRD)
Genes: CNTF
Study 20494902 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20494902 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16919926 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9626806 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 22129607 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22129607 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20514078 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 19892046 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 7904847 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 3323596 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3323596 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24177203 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 10375084 — Biomarker: PLB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLB1; PLB
Study 7358202 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25658017 — Biomarker: Urine free cortisol
Type: Surrogate Endpoint (SUR)
Study 18830236 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study 16921503 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 10364988 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 26859491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19282241 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 16387079 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 12218339 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 12218339 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 31723956 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10903022 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 10903022 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 17414400 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 11953964 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 19808296 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 16772327 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 16772327 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 26467209 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 26467209 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 29264729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20350693 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)