AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 8318480 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21420555 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15386949 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 15386949 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 15386949 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 9834040 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 9834040 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 8590556 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31282081 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 18163016 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 23947316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8871425 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 7123952 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 29695706 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29672747 — Biomarker: ASAH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASAH1; ASAH; HSD-33; HSD33
Study 29694504 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29694504 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 29694504 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 27160957 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24527505 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 20069077 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 20069077 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7906572 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7906572 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3300903 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21035594 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10622067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25402757 — Biomarker: TCP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCP1; CCT1; CCTA
Study 25402757 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25402757 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25402757 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22866292 — Biomarker: LNX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LNX1; LNX; PDZRN2; UNQ574/PRO1136
Study 19349323 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1582275 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28235524 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15450785 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study 6814227 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3878652 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29091471 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 27621189 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 24515273 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 22938661 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 9025126 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1792912 — Biomarker: HRG mRNA
Type: Predictive Biomarker (PRD)
Genes: HRG
Study 1792912 — Biomarker: HHEX mRNA
Type: Predictive Biomarker (PRD)
Genes: HHEX; HEX; PRH; PRHX
Study 30358831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16277798 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9505567 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 30790069 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 30790069 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17485968 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15900306 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12164888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24938711 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 21768610 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 11779098 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 11779098 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 7995329 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25970665 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19916995 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 19916995 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 18376000 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18376000 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11053614 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 11053614 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15919453 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12949361 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12949361 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12949361 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26930568 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 26930568 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26930568 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26930568 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 25203332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22753773 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17662102 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23485413 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 19154656 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 28911085 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 6360055 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 11916904 — Biomarker: GK mRNA
Type: Predictive Biomarker (PRD)
Genes: GK
Study 7586765 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1971504 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24618069 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 8559437 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2558701 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29977072 — Biomarker: ENTPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ENTPD1; CD39
Study 29977072 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22849818 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 25959199 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 25959199 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 30179720 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12975389 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6189412 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 28958152 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27471039 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 20797478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20797478 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20797478 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16239176 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 9116274 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 24261700 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 14652636 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 14652636 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 14652636 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 14652636 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27514411 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27514411 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27514411 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 27514411 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22040450 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 20159176 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20159176 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18470901 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 3580251 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 22319038 — Biomarker: FGFR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 22319038 — Biomarker: FGF8 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF8; AIGF
Study 18487899 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 16174275 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 8732710 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 1745353 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1745353 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study 6979136 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26948070 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25523533 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18753639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11092405 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8477914 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 3103338 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 25850030 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 25850030 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 1704534 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20864251 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 9468364 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31937049 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31937049 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 21439850 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30623563 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28700489 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16384561 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2981086 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29695765 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22361711 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17971707 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17971707 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27288376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27288376 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26908742 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 10335771 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10335771 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28858362 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 28858362 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25944073 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22127508 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16391575 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 12633544 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8518219 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 3830118 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27530188 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 24460597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20636229 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 10583037 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 1725620 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 21412218 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 21412218 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 21412218 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 19643487 — Biomarker: Insulin receptor substrate 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IRS1
Study 9177871 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9177871 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 7954417 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 29452815 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29452815 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29452815 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 20929123 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 18512767 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 8704358 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2054405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22129890 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22129890 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17638699 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15868998 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12774058 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 12774058 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10563609 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 27111089 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18661191 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 12562649 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26675765 — Biomarker: DMGDH mRNA
Type: Predictive Biomarker (PRD)
Genes: DMGDH
Study 26675765 — Biomarker: SELENOP mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENOP; SELP; SEPP1
Study 9696231 — Biomarker: BAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAK1; BAK; BCL2L7; CDN1
Study 7857733 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7857733 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 31605198 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24132976 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24132976 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19675378 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31277120 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 22120032 — Biomarker: ZC3H12D mRNA
Type: Predictive Biomarker (PRD)
Genes: ZC3H12D; C6orf95; MCPIP4; TFL
Study 12383810 — Biomarker: Neurofilament light polypeptide
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: NEFL; NF68; NFL
Study 9578182 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 2533074 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15071126 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 15071126 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11297577 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 11297577 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11297577 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31518023 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 20153794 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 1906745 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1906745 — Biomarker: Interleukin 1 alpha
Type: Safety Biomarker (SAF)
Genes: IL1A; IL1F1
Study 1906745 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 1906745 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 25081694 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9498433 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 26141208 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 26141208 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 23258572 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22129852 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 17442229 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17442229 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15536162 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 15536162 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15522983 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 88708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31177099 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27769783 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 27769783 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 19705518 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19705518 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11231744 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22278628 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15625266 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 15894149 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24219348 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9259871 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29381791 — Biomarker: HFE mRNA
Type: Predictive Biomarker (PRD)
Genes: HFE; HLAH
Study 20856164 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 788745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21559793 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 21559793 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2