AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 12898884 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 31151464 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 21296446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11467142 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 2848604 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2848604 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30251879 — Biomarker: C1QL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 15746991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11955844 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10206072 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 10206072 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 17968434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9738560 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2975612 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21474134 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 18341663 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 9085405 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 9085405 — Biomarker: PTK7 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTK7; CCK4
Study 18829518 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19552838 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19552838 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 14743850 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 14743850 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9476036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27019267 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10217339 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 10217339 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 24426779 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3275684 — Biomarker: PBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PBX1; PRL
Study 31444252 — Biomarker: Serum asparaginase
Type: Surrogate Endpoint (SUR)
Study 28425272 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 11325669 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11325669 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9934406 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 19490477 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19490477 — Biomarker: CCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR4; CMKBR4
Study 19490477 — Biomarker: CXCR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR3; GPR9
Study 9102064 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 29128898 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24337734 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1671875 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study 16396651 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8027273 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 7342 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31885153 — Biomarker: RBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBP4; PRO2222
Study 31885153 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 31621256 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31621256 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 31621256 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25742762 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 23817699 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20215537 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 20215537 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 16754711 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 16754711 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 31441999 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10049657 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8523926 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 31322918 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21342170 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 11451781 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11451781 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 26861113 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 10671945 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 25277334 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15145973 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 11920261 — Biomarker: VIM mRNA
Type: Predictive Biomarker (PRD)
Genes: VIM
Study 31740463 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 22248871 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15687112 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 10086794 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10086794 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 27673483 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15008996 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15008996 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26057917 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 24152688 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 24152688 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24152688 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28337876 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 23052033 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22073219 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16446752 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 10694768 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24628464 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 22031515 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 20696074 — Biomarker: FTL mRNA
Type: Predictive Biomarker (PRD)
Genes: FTL
Study 3109142 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25179788 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 25179788 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 10634964 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31426749 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26402762 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 24088280 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19626385 — Biomarker: TCP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCP1; CCT1; CCTA
Study 10352494 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 7655780 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28467116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25599690 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25599690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18216051 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 14690014 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10378072 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26931369 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 26931369 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26931369 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20235638 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9366459 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1286492 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15075543 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31353231 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 31353231 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26011261 — Biomarker: PCSK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK5; PC5; PC6
Study 26011261 — Biomarker: SUB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SUB1; PC4; RPO2TC1
Study 29570164 — Biomarker: CIT mRNA
Type: Predictive Biomarker (PRD)
Genes: CIT; CRIK; KIAA0949; STK21
Study 24811615 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24811615 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 16143248 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 16143248 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12756512 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 8595083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1709446 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1709446 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11268266 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11268266 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2567793 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 107583 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 18668363 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18668363 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 18668363 — Biomarker: PGR mRNA
Type: Predictive Biomarker (PRD)
Genes: PGR; NR3C3
Study 18668363 — Biomarker: ESR1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ESR1; ESR; NR3A1
Study 14989560 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 10752807 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10752807 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10752807 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 10752807 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 14681342 — Biomarker: EDNRA mRNA
Type: Predictive Biomarker (PRD)
Genes: EDNRA; ETA; ETRA
Study 14681342 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30161291 — Biomarker: Interleukin 7 receptor alpha
Type: Pharmacodynamic Biomarker (PDY)
Genes: IL7R
Study 30161291 — Biomarker: STAT5A mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT5A; STAT5
Study 30161291 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25907945 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25907945 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21715516 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21715516 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21715516 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21715516 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 11430324 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30086484 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30086484 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 23592533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17031012 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31142474 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31142474 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23732250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12577417 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23588257 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8793702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18848350 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10813108 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 29649992 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27067521 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26598141 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17062301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10941607 — Biomarker: NES mRNA
Type: Predictive Biomarker (PRD)
Genes: NES; Nbla00170
Study 20218813 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 2039996 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2039996 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30224345 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 26655003 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26655003 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12051574 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24927031 — Biomarker: RHOJ mRNA
Type: Predictive Biomarker (PRD)
Genes: RHOJ; ARHJ; RASL7B; RHOI; TCL
Study 19727679 — Biomarker: SLC6A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 7516641 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 18487567 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 18487567 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29431140 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 25184356 — Biomarker: NOTCH3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOTCH3
Study 20005545 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 27862715 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 9573749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8158885 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8158885 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20143872 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 20143872 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 10808678 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20831697 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8196254 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26204531 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 25756419 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 25756419 — Biomarker: IL2
Type: Predictive Biomarker (PRD)
Genes: IL-2; TCGF
Study 25756419 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 25756419 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 25756419 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25756419 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 25756419 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 25756419 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 25756419 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25756419 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23187936 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 23187936 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19506932 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 19506932 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 16284083 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 9497875 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 19002337 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 9817939 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9817939 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9817939 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 9817939 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11809090 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11809090 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25449505 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 23016708 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 17398308 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 8745384 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 1716979 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 27592224 — Biomarker: SCARA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SCARA3; CSR
Study 9477052 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 2795592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 346293 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 346293 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28806982 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 12536650 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 23981966 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 17716376 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3303001 — Biomarker: CPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPZ
Study 25600169 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23281174 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 22452896 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 17298881 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 17298881 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15379144 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)