AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 16418138 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 31587090 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 31587090 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 20385930 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 17371829 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28830669 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25252593 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 15309209 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15309209 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17598653 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12059914 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 1259126 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31864809 — Biomarker: CNR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNR1; CNR
Study 23908084 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 21983214 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 7845792 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 29292054 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21317794 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 21317794 — Biomarker: CCR2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCR2; CMKBR2
Study 21317794 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21317794 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21317794 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 9062488 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 7934009 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7934009 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 27544607 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 25535691 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 29686027 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29686027 — Biomarker: TNFRSF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1A; TNFAR; TNFR1
Study 29686027 — Biomarker: TNFRSF1B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1B; TNFBR; TNFR2
Study 29686027 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24102806 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 20884874 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 20884874 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16756147 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 16756147 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 27406897 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 24192055 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18206038 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 16366235 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8549941 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7701171 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31706719 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31706719 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 21174209 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18806550 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18806550 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 18806550 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10827334 — Biomarker: NES mRNA
Type: Predictive Biomarker (PRD)
Genes: NES; Nbla00170
Study 8624759 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29500848 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29500848 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 29500848 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 26854355 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 17367769 — Biomarker: APOC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOC3
Study 17367769 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 31659794 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 16555157 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 16555157 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24158761 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 8620970 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 28463879 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23148565 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 9313664 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 30261896 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30261896 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 30261896 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 30261896 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25919120 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 19460761 — Biomarker: TGFB1
Type: Safety Biomarker (SAF)
Genes: CED; TGFbeta
Study 19460761 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 19460761 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19460761 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 19460761 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16826487 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 16826487 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 10890632 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 10890632 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 1574014 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27912954 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10680028 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18714251 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 18714251 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 1609997 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3723795 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22878491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20049465 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 3300241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27197908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27197908 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18516353 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18516353 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 18516353 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 10539777 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 28949260 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 28949260 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28949260 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 28949260 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 15116352 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 8249842 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27367521 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27367521 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15639633 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 9445198 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 9445198 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9445198 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7573232 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 6670732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6670732 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 15115831 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29417495 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29417495 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18248281 — Biomarker: BAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAK1; BAK; BCL2L7; CDN1
Study 16569261 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8624266 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 29961573 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19484982 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 7592245 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 2547139 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 27190095 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 20889387 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 12548313 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12548313 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31267688 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30372645 — Biomarker: ENG mRNA
Type: Predictive Biomarker (PRD)
Genes: ENG; END
Study 22403884 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10473080 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 25146063 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9133941 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12576812 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 12576812 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 8784742 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 20558037 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15962224 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26743348 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 26743348 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 18089905 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18089905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31638498 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 30092876 — Biomarker: TSC2
Type: Predictive Biomarker (PRD)
Genes: tuberin; LAM; PPP1R160
Study 30092876 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25133164 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22417778 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22417778 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20966122 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 14766942 — Biomarker: LIF mRNA
Type: Predictive Biomarker (PRD)
Genes: LIF; HILDA
Study 28489637 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25491493 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 25491493 — Biomarker: ABCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 20798655 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12956861 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 12956861 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12956861 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 19589539 — Biomarker: FUT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FUT1; H; HSC
Study 19589539 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 19589539 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 12575371 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 22490715 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 17892610 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12364444 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6351586 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26135553 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19388505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9554567 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21761706 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 19258920 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 16961676 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17693905 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17693905 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 12040440 — Biomarker: HRG mRNA
Type: Predictive Biomarker (PRD)
Genes: HRG
Study 12040440 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25564797 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 9836523 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 2680230 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19809308 — Biomarker: ADAMTS13 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 19809308 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 2642658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 938161 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 30763457 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 30763457 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 22171802 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2907080 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21608219 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 21608219 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 10653873 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 8218004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26945918 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 23990572 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 23990572 — Biomarker: SLC38A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 19783599 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 19166443 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 19166443 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 19166443 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19166443 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23069315 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 17898183 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 31339232 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22187792 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19001516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19001516 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 19001516 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22094092 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22094092 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3546611 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 3546611 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 12825092 — Biomarker: ADORA2A
Type: Safety Biomarker (SAF)
Genes: RDC8
Study 15882879 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 19194341 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16014067 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 6184567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20636634 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 9871427 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8563674 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30937600 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 26299324 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 24060577 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24060577 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 21119518 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 18069178 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 27368430 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26556688 — Biomarker: TSPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPO; BZRP; MBR
Study 26556688 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 20592389 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9893539 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15164336 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 15164336 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 15164336 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28687830 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 21252053 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17000366 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 29724499 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24088680 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12716076 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12716076 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)