AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 18020004 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 25854019 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 21148662 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22323575 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 20226430 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15580479 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15312253 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15312253 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 16340629 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16340629 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14550800 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 6389909 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 14620302 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 28301435 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 16750207 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18795367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18795367 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 16918520 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2446055 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19755414 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 19755414 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 23590986 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 21664512 — Biomarker: LIF mRNA
Type: Predictive Biomarker (PRD)
Genes: LIF; HILDA
Study 12700448 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11121720 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31349945 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31349945 — Biomarker: AIP mRNA
Type: Predictive Biomarker (PRD)
Genes: AIP; XAP2
Study 31349945 — Biomarker: CENPJ mRNA
Type: Predictive Biomarker (PRD)
Genes: CENPJ; CPAP; LAP; LIP1
Study 31349945 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 31349945 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31349945 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 28096757 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28096757 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16797309 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12587810 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21675122 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 21675122 — Biomarker: BLOC1S2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BLOC1S2; BLOS2; CEAP
Study 21675122 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 21675122 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 21675122 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31742881 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 31742881 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31742881 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25771851 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25771851 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25771851 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25771851 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 31978225 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 31978225 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 31978225 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16931264 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12601528 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30872737 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24577471 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 17110604 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17110604 — Biomarker: CPT1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CPT1A; CPT1
Study 17110604 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 17110604 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 17110604 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17110604 — Biomarker: Peroxisome proliferator-activated receptor delta
Type: Safety Biomarker (SAF)
Genes: PPARD
Study 27322311 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 21542114 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 30782715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20828790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11427833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28291587 — Biomarker: MNT mRNA
Type: Predictive Biomarker (PRD)
Genes: MNT; BHLHD3; ROX
Study 27168265 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9592991 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 7512433 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 18267006 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 17087052 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17087052 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25864872 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 21801494 — Biomarker: XDH mRNA
Type: Predictive Biomarker (PRD)
Genes: XDH; XDHA
Study 21801494 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 7706699 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31365829 — Biomarker: RHD mRNA
Type: Predictive Biomarker (PRD)
Genes: RHD
Study 24740462 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24740462 — Biomarker: MEFV mRNA
Type: Predictive Biomarker (PRD)
Genes: MEFV; MEF; TRIM20
Study 18501499 — Biomarker: FGFR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR3; JTK4
Study 18501499 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study 31880966 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 11513193 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 9640077 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 26948991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24357575 — Biomarker: CGAS mRNA
Type: Predictive Biomarker (PRD)
Genes: CGAS; C6orf150; MB21D1
Study 21899712 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 23782513 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 16476843 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8603558 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 1419473 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1419473 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29716756 — Biomarker: RRS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RRS1; KIAA0112; RRR
Study 23227677 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20722847 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18388249 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7580706 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2068533 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 9679794 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7983283 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 26919735 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 3812270 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25675113 — Biomarker: miR-223
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR223
Study 25675113 — Biomarker: let-7b
Type: Predictive Biomarker (PRD)
Genes: MIRLET7B
Study 23616512 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23616512 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 23616512 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19001792 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 17283875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28332096 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 26133996 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 26133996 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18165577 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 16096330 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 31216065 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 22448235 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18025896 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15159722 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1972207 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22097200 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 22097200 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22097200 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 22097200 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 14659974 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 7951099 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 7526067 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7526067 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26754182 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 24943987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23286297 — Biomarker: KIF22 mRNA
Type: Predictive Biomarker (PRD)
Genes: KIF22; KID; KNSL4
Study 17976963 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 17976963 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 15871443 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 31444999 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31444999 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31444999 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31444999 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 26924549 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 22424025 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 22424025 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17499999 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17499999 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30946156 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17315084 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15038622 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15038622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7837014 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 3414406 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31922432 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28611110 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23374898 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23374898 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23374898 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23374898 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23374898 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16390499 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 16390499 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10929446 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 4003919 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20537455 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 20537455 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 29446445 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 24465425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24465425 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24465425 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24465425 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10624546 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 30156056 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 31495201 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 17338766 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 28972192 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 15024666 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17693902 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17693902 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17297830 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12941060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9199606 — Biomarker: DDR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 2580177 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2580177 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 30382485 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 29879277 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 26927908 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 26927908 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 25326008 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 19458624 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15831604 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14601488 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 14601488 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 14601488 — Biomarker: GCSAM mRNA
Type: Predictive Biomarker (PRD)
Genes: GCSAM; GAL; GCET2
Study 6784917 — Biomarker: TIMM8A mRNA
Type: Predictive Biomarker (PRD)
Genes: TIMM8A; DDP; DDP1; TIM8A
Study 6784917 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 26559501 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10714911 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 10714911 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9468004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23932548 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 15597521 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11374699 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 1512689 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1512689 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 1512689 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 31283835 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31689007 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31689007 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10898413 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 8817407 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1422288 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 4059722 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2897305 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 2897305 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23020859 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23020859 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23020859 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 15937908 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 2547411 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15112887 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 7946161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25653155 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 25653155 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21118844 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 21118844 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 12907532 — Biomarker: Nasal potential difference
Type: Pharmacodynamic Biomarker (PDY)
Study 12907532 — Biomarker: CFTR
Type: Predictive Biomarker (PRD)
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 30222842 — Biomarker: TPSG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPSG1; PRSS31; TMT
Study 19889524 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19889524 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11854116 — Biomarker: FGF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF2; FGFB
Study 28874142 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 28874142 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30562322 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10355512 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 10355512 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC
Study 8952741 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20048489 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 2949910 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 30503129 — Biomarker: GHR mRNA
Type: Predictive Biomarker (PRD)
Genes: GHR
Study 30503129 — Biomarker: BMPR1B mRNA
Type: Predictive Biomarker (PRD)
Genes: BMPR1B
Study 7572748 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2145237 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30770294 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI