AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 30712247 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 30712247 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 30712247 — Biomarker: CYP4F2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP4F2
Study 21251805 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 21251805 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 19878793 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 17761981 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 9138853 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7681516 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25311998 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20837352 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11849868 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31194885 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31194885 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 29871185 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 24589090 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 17991638 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 17991638 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17991638 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17991638 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 17991638 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 17991638 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 17991638 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16169320 — Biomarker: DUSP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DUSP2; PAC1
Study 2860268 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31965906 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31965906 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 31965906 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 31965906 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 27514766 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18721577 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 10597050 — Biomarker: SEMG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEMG1; SEMG
Study 8739163 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 17550348 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1325513 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1325513 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24644106 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 24644106 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 1407240 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 20186436 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20186436 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27993433 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10983907 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 10983907 — Biomarker: MGAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MGAT1; GGNT1; GLCT1; GLYT1; MGAT
Study 10912884 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1718243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31296586 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 20650012 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 17993030 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 15138667 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 3063506 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8395488 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24473249 — Biomarker: FGA mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGA
Study 15775780 — Biomarker: NANOS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS3; NOS3
Study 15775780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1374201 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27269942 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 22873700 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18405704 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 16472719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10235107 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30978434 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30978434 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20156053 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 14568851 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 10930151 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 31663569 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 21680653 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 18566109 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 8436747 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31468364 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 25222185 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25222185 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 25222185 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27959613 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27959613 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21178939 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10459562 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2113567 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 2113567 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 37871 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27978548 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 27978548 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 27978548 — Biomarker: DHCR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: DHCR7; D7SR
Study 27978548 — Biomarker: CYP2R1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2R1
Study 27978548 — Biomarker: CYP27B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 27978548 — Biomarker: CYP24A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP24A1; CYP24
Study 27978548 — Biomarker: CASR mRNA
Type: Predictive Biomarker (PRD)
Genes: CASR; GPRC2A; PCAR1
Study 8139380 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 8139380 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29658856 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 22998533 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22998533 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22998533 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21647656 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18379534 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16670153 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 1396829 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 1396829 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 4061896 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 4061896 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30721637 — Biomarker: TCF7L2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCF7L2; TCF4
Study 29234038 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29234038 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 29234038 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 29234038 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 29234038 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29234038 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 23625305 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23625305 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23625305 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31296936 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31296936 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31296936 — Biomarker: Alpha-1-acid glycoprotein 1
Type: Monitoring Biomarker (MOI)
Genes: ORM1; AGP1
Study 19548011 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 18689569 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31125468 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 24988955 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 20450503 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 12195113 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 12195113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1683148 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21071588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26858331 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 19817561 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 17455733 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 26630416 — Biomarker: LSS mRNA
Type: Predictive Biomarker (PRD)
Genes: LSS; OSC
Study 26734916 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 24583792 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 14679075 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 9053816 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27905499 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 27905499 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 19063834 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 19063834 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 19063834 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 15736890 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 1670585 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29247068 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29247068 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19349153 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 17447657 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 196518 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28452989 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 25740607 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 19014837 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 8443808 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8443808 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 8443808 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 8443808 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 18773156 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25332472 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20456336 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 20456336 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 20456336 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 11889427 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 11889427 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10213466 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 2141757 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 2141757 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19132974 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 19132974 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 19132974 — Biomarker: KIT
Type: Predictive Biomarker (PRD)
Genes: CD117; SCFR; C-Kit
Study 19132974 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 14722203 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 3145297 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 30661697 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 30661697 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30661697 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30661697 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 23351822 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 16965429 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 15292315 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24596084 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14530982 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11412248 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11412248 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 29483043 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20490354 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20490354 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 20490354 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12811362 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 8472828 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 30807234 — Biomarker: CCNE1 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCNE1; CCNE
Study 30807234 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 30807234 — Biomarker: CDK6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK6; CDKN6
Study 30807234 — Biomarker: Retinoblastoma-associated protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: RB1
Study 30393030 — Biomarker: TNR mRNA
Type: Predictive Biomarker (PRD)
Genes: TNR
Study 30393030 — Biomarker: TKTL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TKTL1; TKR; TKT2
Study 12015188 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12015188 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19125990 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 8478759 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31700615 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 23335852 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 23335852 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20358358 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11226087 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19657112 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 16920503 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15309484 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 7986856 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 23934169 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1962905 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 1962905 — Biomarker: LIPC mRNA
Type: Predictive Biomarker (PRD)
Genes: LIPC; HTGL
Study 26302142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21406499 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18192510 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10568568 — Biomarker: KY mRNA
Type: Predictive Biomarker (PRD)
Genes: KY
Study 7061569 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 23038750 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9833596 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30700356 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28493519 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 2859421 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 24773760 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 22466942 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 2220647 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2220647 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17377504 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30264293 — Biomarker: MAP2K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K1; MEK1; PRKMK1
Study 30264293 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25524478 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 25524478 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 25524478 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 17577104 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9115054 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26052959 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 26052959 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 26052959 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26052959 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 26052959 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 23952947 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23952947 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2