AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 28116649 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 28116649 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24956970 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24956970 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19380868 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 19380868 — Biomarker: Interleukin 7 receptor alpha
Type: Pharmacodynamic Biomarker (PDY)
Genes: IL7R
Study 2700773 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 166929 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 24720526 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24720526 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9290118 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 8365385 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3602015 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25462913 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 10349922 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12595492 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 11042235 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30606259 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29445928 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26334249 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 23069270 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23069270 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20497416 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 20497416 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 29105521 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 25147328 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 12587107 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 2471025 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 169536 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31871140 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 10757556 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11940375 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 11940375 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11107582 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8571309 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 8571309 — Biomarker: PPIC mRNA
Type: Predictive Biomarker (PRD)
Genes: PPIC; CYPC
Study 8571309 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 1748139 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6760679 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30923313 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 12042891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22106341 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19843623 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 12117445 — Biomarker: Heart fatty acid-binding protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FABP3; FABP11; MDGI
Study 8568293 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 29893313 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 27454135 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27454135 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31240711 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28321566 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 19148110 — Biomarker: TNFA
Type: Predictive Biomarker (PRD)
Genes: TNF; TNFSF2; DIF; TNF-alpha
Study 19148110 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3525055 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 3525055 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 26631904 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27543500 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27543500 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 22493073 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8393365 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25909463 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21219391 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 18502262 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 18502262 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9175683 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31839677 — Biomarker: DUSP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DUSP4; MKP2; VH2
Study 31839677 — Biomarker: ETV4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV4; E1AF; PEA3
Study 18555932 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21885077 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17854028 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17854028 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 26148007 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 26148007 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24019080 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 20683457 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18460997 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 1414967 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 23508598 — Biomarker: UST mRNA
Type: Predictive Biomarker (PRD)
Genes: UST; DS2ST
Study 10778966 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 1523877 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 2994989 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2994989 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31771407 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 31771407 — Biomarker: IRX3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRX3; IRXB1
Study 22474933 — Biomarker: APEX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 11239759 — Biomarker: TWIST1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TWIST1; BHLHA38; TWIST
Study 24944062 — Biomarker: DHFR mRNA
Type: Predictive Biomarker (PRD)
Genes: DHFR
Study 24944062 — Biomarker: DHFR
Type: Safety Biomarker (SAF)
Genes: DHFR1
Study 9800234 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 22230999 — Biomarker: IMPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IMPA1; IMPA
Study 31125308 — Biomarker: TFG mRNA
Type: Predictive Biomarker (PRD)
Genes: TFG
Study 21419169 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 21419169 — Biomarker: N-acetylneuraminic acid
Type: Safety Biomarker (SAF)
Study 11213852 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 25769357 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 25769357 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 30982443 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20184129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31087564 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28289237 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 28289237 — Biomarker: GLS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS2; GA
Study 26411504 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 16448895 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16448895 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 16448895 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2872804 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9284777 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8392359 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 17226852 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 16114787 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12134227 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1536959 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 15073109 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 15073109 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 17961161 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 14636765 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 18042053 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12095058 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12095058 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 30767253 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 30767253 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21296603 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16412857 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16412857 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16412857 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16412857 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 29125992 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 10407881 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7750306 — Biomarker: ARID3B mRNA
Type: Predictive Biomarker (PRD)
Genes: ARID3B; BDP; DRIL2
Study 21352660 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 22550938 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 7007060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19818223 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 11961019 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9405732 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2668462 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31220863 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 22117841 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 18562790 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 18562790 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 27173472 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 27173472 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 20738456 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 31721892 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 31721892 — Biomarker: HTR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2A; HTR2
Study 31721892 — Biomarker: TPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH1; TPH; TPRH; TRPH
Study 31721892 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 31721892 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 31721892 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 29071931 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 17971285 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21629249 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 19081527 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30736832 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30953791 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 24046302 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21898590 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2916452 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 26303628 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19334068 — Biomarker: ERCC2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MAG; EM9; MGC102762; MGC126218; MGC126219
Study 19334068 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15948237 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 29650706 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 29650706 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29650706 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29650706 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19766209 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23357149 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21343239 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 10828731 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 7917158 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7917158 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31792258 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 1557681 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 3891615 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24885096 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 19903661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10610644 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21940091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12459865 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20060192 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 20060192 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 15452689 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 11849315 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 11849315 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9408071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12681875 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8864323 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21041432 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21041432 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31359143 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28002688 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 21924882 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 11085323 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29779262 — Biomarker: SPRR1A mRNA
Type: Predictive Biomarker (PRD)
Genes: SPRR1A
Study 29779262 — Biomarker: TET3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET3; KIAA0401
Study 29779262 — Biomarker: FAM25A mRNA
Type: Predictive Biomarker (PRD)
Genes: FAM25A
Study 29779262 — Biomarker: CRCT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CRCT1; C1orf42; NICE1
Study 24714489 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23970114 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 23970114 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 10999788 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10999788 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8636808 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1512513 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30012185 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 30012185 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26728060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22178174 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15745726 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14619641 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12078788 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12078788 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 2636677 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16877197 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16877197 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27344822 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 27344822 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27344822 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 22388234 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 15676086 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19022155 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 12610862 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 10234295 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 25149383 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 25149383 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16194475 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27118107 — Biomarker: MYCL mRNA
Type: Predictive Biomarker (PRD)
Genes: MYCL; BHLHE38; LMYC; MYCL1
Study 27118107 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 23283367 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18434729 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10704624 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 10704624 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 25286914 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12648865 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 10488413 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 1872724 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31095287 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 11295959 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9168293 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8287830 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 2215101 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17719703 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9846802 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 25914483 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25914483 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20649626 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 20649626 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20649626 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 12791813 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)