AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 9237086 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9237086 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 28206674 — Biomarker: NR4A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR4A1; GFRP1; HMR; NAK1
Study 25898052 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 12499977 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 12499977 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8672752 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 8672752 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 29848902 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29848902 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29848902 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25237981 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25237981 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17700333 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 12153969 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 12153969 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 10915394 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10915394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10915394 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 2370014 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28452195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25485803 — Biomarker: CFL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CFL1; CFL
Study 28741272 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26034004 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 23349254 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 23349254 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 17186970 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 26323735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21711463 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 21711463 — Biomarker: POMC mRNA
Type: Predictive Biomarker (PRD)
Genes: POMC
Study 19419855 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 24083754 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18366084 — Biomarker: SFPQ mRNA
Type: Predictive Biomarker (PRD)
Genes: SFPQ; PSF
Study 23116683 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 12746781 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25237 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9387966 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 22326841 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 22326841 — Biomarker: ANKK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANKK1; PKK2; SGK288
Study 12428223 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 27467969 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 18316422 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 10651230 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27112532 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 27112532 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 22036871 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11895063 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11895063 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23458257 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18387444 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 16631617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31551204 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31551204 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 24495849 — Biomarker: SLC10A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC10A3; DXS253E; P3
Study 16943848 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 15827103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30453910 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 30453910 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 26195001 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23824463 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 23824463 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23824463 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21161463 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 16192577 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9468205 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 27140800 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21810677 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 17268417 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 17268417 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 9457393 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30134549 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 30134549 — Biomarker: HSPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPD1; HSP60
Study 30134549 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study 30134549 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20105396 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 22269590 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22269590 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9129563 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 30561227 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29967525 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 10551192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30068817 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 26843796 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24484726 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 19606092 — Biomarker: RAB8A mRNA
Type: Predictive Biomarker (PRD)
Genes: RAB8A; MEL; RAB8
Study 17697058 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17697058 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15353873 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15353873 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11593101 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14632537 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 1444872 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 1444872 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24286335 — Biomarker: OSM mRNA
Type: Predictive Biomarker (PRD)
Genes: OSM
Study 11109505 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9122904 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 27659741 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 18438853 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16290232 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 16290232 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 16290232 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 11045316 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 9363869 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1607916 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 3769194 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 16151471 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 9569080 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 31756059 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 22309046 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 8551492 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 396063 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17461981 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15465744 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 8010332 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 8010332 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21057823 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 7664428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23395281 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 23395281 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 23395281 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 31138727 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31138727 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 31138727 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31138727 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 31753429 — Biomarker: STAR mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAR; STARD1
Study 23232827 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 9744493 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16749414 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9783333 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 17958029 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 17958029 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 15266329 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 15266329 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15266329 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27720142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1487552 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1487552 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1487552 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 25218903 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 31302276 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 14517597 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 14517597 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30096139 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20207521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10339777 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1709185 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 1709185 — Biomarker: RNASE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RNASE2; EDN; RNS2
Study 17350969 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10302355 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 28127204 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 9686498 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 12874608 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8560674 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 30617197 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 30617197 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 30239561 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 11880561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10193912 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8566890 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31190609 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31190609 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16772904 — Biomarker: TICAM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TICAM2; TIRAP3; TIRP; TRAM
Study 11232016 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 11232016 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11232016 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8430630 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 29406607 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21372246 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 18309452 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 8938284 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 8938284 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 29452031 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23934773 — Biomarker: PDIA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PDIA3; ERP57; ERP60; GRP58
Study 23934773 — Biomarker: Glutathione S-transferase P
Type: Safety Biomarker (SAF)
Genes: GSTP1; FAEES3; GST3
Study 8952582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11673815 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25450847 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25450847 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1677820 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 28070882 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 17402468 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 7931040 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7931040 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31662030 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 9082675 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 25894405 — Biomarker: SOCS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOCS3; CIS3; SSI3
Study 25894405 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17206669 — Biomarker: Bacteroidetes phylum
Type: Safety Biomarker (SAF)
Study 28467859 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8857441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6305546 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 6305546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31432311 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 27006286 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24927970 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 24927970 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 8094279 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18566593 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 16336334 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 16336334 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 7496696 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31412895 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29562156 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 29562156 — Biomarker: Chromosome 17p
Type: Predictive Biomarker (PRD)
Study 12365197 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 7406204 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 26187233 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 23573255 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 16440148 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 16440148 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16440148 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 10891820 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8979288 — Biomarker: Urine free cortisol
Type: Surrogate Endpoint (SUR)
Study 3519883 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 28381428 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 20226502 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 19213341 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19213341 — Biomarker: Urinary total protein
Type: Safety Biomarker (SAF)
Study 1457271 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1457271 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 30446494 — Biomarker: FANCL mRNA
Type: Predictive Biomarker (PRD)
Genes: FANCL; PHF9
Study 30446494 — Biomarker: CDKN2A mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2A; CDKN2; MTS1
Study 30446494 — Biomarker: CREBBP mRNA
Type: Predictive Biomarker (PRD)
Genes: CREBBP; CBP
Study 30446494 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 16125499 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 11831838 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7494939 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29587875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22647889 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18344886 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 30526678 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28356129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23650505 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 22417251 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 12859160 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 24637941 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 24637941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24637941 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8624887 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16996597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3553480 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22939758 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 16801459 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 30175844 — Biomarker: RASA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RASA4; CAPRI; GAPL; KIAA0538
Study 30175844 — Biomarker: DHFR mRNA
Type: Predictive Biomarker (PRD)
Genes: DHFR
Study 30175844 — Biomarker: DHFR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DHFR2; DHFRL1; DHFRP4
Study 17885011 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 17885011 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 17885011 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17885011 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 17885011 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 28231822 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE