AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 28089917 — Biomarker: miR-21
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR21
Study 22785005 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 12153960 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 12153960 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 12153960 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 30207807 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 1546861 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 1546861 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16827248 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11106211 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21799442 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21799442 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27329547 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 23106931 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 31679946 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 23375165 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 8362600 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 27849566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27849566 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 27849566 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 21227601 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 16480471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8237748 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29033381 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17655686 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28925467 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21546500 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 20214327 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 20214327 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2657428 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21867540 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 11325088 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29903120 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22776750 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22776750 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 8576819 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 2663800 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 26568588 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23223314 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 11687611 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10423615 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 8175218 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30172948 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30172948 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24193868 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 23879079 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 18065810 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 18065810 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 16427266 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 14688490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3707675 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29266564 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 18279468 — Biomarker: Angiotensinogen
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: AGT; SERPINA8
Study 18279468 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 18279468 — Biomarker: AGTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study 18279468 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 18279468 — Biomarker: BDKRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BDKRB2; BKR2
Study 11372005 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 3687360 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 21097793 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 3436157 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 27317442 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25256183 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11521797 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 9846284 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8279372 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18576337 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 18576337 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27004617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11712808 — Biomarker: UBC mRNA
Type: Predictive Biomarker (PRD)
Genes: UBC
Study 11712808 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9222938 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9222938 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8381164 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 19321581 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 11318080 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22554294 — Biomarker: CLIC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLIC1; G6; NCC27
Study 18053320 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12571543 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1458072 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31641322 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24793078 — Biomarker: ALKBH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALKBH1; ABH; ABH1; ALKBH
Study 18574656 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 24401815 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18191112 — Biomarker: FKBP5 mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: FKBP5; AIG6; FKBP51
Study 15696076 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 15696076 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 8542158 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 24705587 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 24705587 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15638899 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15638899 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 8489308 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 8489308 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 16630553 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 16630553 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 15012730 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 21887804 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18021136 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 11191041 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11191041 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 10780258 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7828296 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7828296 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2240382 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29083219 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 19821969 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11743506 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 8168332 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1546065 — Biomarker: PCLAF mRNA
Type: Predictive Biomarker (PRD)
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 29886815 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 29886815 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23288914 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16626573 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 16626573 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30129666 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23527347 — Biomarker: CPE mRNA
Type: Predictive Biomarker (PRD)
Genes: CPE
Study 9266623 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17762286 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 11865274 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8786245 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2079571 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31082269 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9507512 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 31289983 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 27856633 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 20731006 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 12094254 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 12094254 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 12094254 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26460886 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 19546252 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 14682411 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1622739 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 1622739 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 1622739 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 1622739 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30805949 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 28528859 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 23458037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11345755 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31779791 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 22782463 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18948612 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 18948612 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 10967612 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 8864962 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 6084139 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6084139 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 27300579 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 22672148 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7540965 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 762813 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23986780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21845243 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 7933838 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 10769276 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study 28302952 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16875647 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 3318455 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3318455 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3318455 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 29934374 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 7588456 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 7588456 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 7588456 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2121394 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 582772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27810347 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23299013 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 8288160 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8288160 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27863277 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 27863277 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 27863277 — Biomarker: IGFBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP1; IBP1
Study 24332524 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24332524 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24332524 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 24332524 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 18315510 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12362231 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10399995 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8991841 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12427056 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 9112275 — Biomarker: MMD mRNA
Type: Predictive Biomarker (PRD)
Genes: MMD; PAQR11
Study 1742583 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 7038189 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 28251822 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 20412274 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9627917 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23179024 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 21349479 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21349479 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10971327 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 20605871 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 17433950 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26578308 — Biomarker: EED mRNA
Type: Predictive Biomarker (PRD)
Genes: EED
Study 18438407 — Biomarker: MRPS30 mRNA
Type: Predictive Biomarker (PRD)
Genes: MRPS30; PDCD9; BM-047
Study 18438407 — Biomarker: FGFR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR2; BEK; KGFR; KSAM
Study 18438407 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 15774846 — Biomarker: SCGB1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SCGB1A1; CC10; CCSP; UGB
Study 1975995 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23624336 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 20859301 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20859301 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20859301 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 28155101 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26848765 — Biomarker: UCP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP3; SLC25A9
Study 26848765 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17008798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16120091 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 9451475 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 9451475 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28600309 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26749228 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19366978 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8431048 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 8431048 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8431048 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 30671061 — Biomarker: CD55 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD55; CR; DAF
Study 30671061 — Biomarker: CD300LF mRNA
Type: Predictive Biomarker (PRD)
Genes: CD300LF; CD300F; CLM1; IGSF13; IREM1; NKIR; UNQ3105/PRO10111
Study 26466937 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19908105 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10376571 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 31011758 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 19093205 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 17893038 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 15108115 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11672828 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 11672828 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 11672828 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 28632487 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 25580869 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16500336 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16500336 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8968014 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29901417 — Biomarker: SIRT6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIRT6; SIR2L6