AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 22594907 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28045766 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19747021 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30617950 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30617950 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28899222 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24113197 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24113197 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24113197 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31751449 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18191048 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 18191048 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 18191048 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8237806 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 27127913 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23253957 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 20389141 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 20389141 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 18241756 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 30887581 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15381923 — Biomarker: RGS4 mRNA
Type: Predictive Biomarker (PRD)
Genes: RGS4
Study 12160194 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31165191 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 18070204 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 1735269 — Biomarker: PTPRF mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRF; LAR
Study 30915650 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30915650 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30915650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18622283 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 18622283 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 18622283 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25069759 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 17934240 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 11932277 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11932277 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16415894 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16415894 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 14760948 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 14760948 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 11369502 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 11369502 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1517383 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 1517383 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 1517383 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 31955491 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 31955491 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 31955491 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29794738 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29188876 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 24100785 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 28468616 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 21436319 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26972606 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11122886 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 23452940 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27737714 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10373048 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8561069 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1652597 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22922768 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20519806 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 20519806 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 18230824 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26795282 — Biomarker: CCR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR5; CMKBR5
Study 26795282 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 26795282 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 26795282 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26795282 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 26795282 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20546629 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 14521272 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 8526786 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 278459 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 278459 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24068472 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 7433340 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7433340 — Biomarker: 51Cr-EDTA
Type: Safety Biomarker (SAF)
Study 30393950 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 25604346 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28155333 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 19141327 — Biomarker: Urine free cortisol
Type: Surrogate Endpoint (SUR)
Study 15162076 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 10795118 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 1549937 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28233454 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 18958548 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 18958548 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 1576099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30315670 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 24981311 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 22177821 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18398639 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18398639 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 10784386 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 19863361 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16759927 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15025600 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28333318 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 25973439 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25973439 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 16289977 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16289977 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16289977 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8490070 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24973959 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 20125186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18305548 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 18305548 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 18305548 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 10228046 — Biomarker: FCGR2B
Type: Predictive Biomarker (PRD)
Genes: CD32; CD32B; FcgammaRIIb; FcGRIIB
Study 2029988 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study 28644246 — Biomarker: KIR2DS4 mRNA
Type: Predictive Biomarker (PRD)
Genes: KIR2DS4; CD158I; KKA3; NKAT8
Study 24474552 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7700069 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7700069 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29706497 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 19615825 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 12604935 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10817726 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10817726 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28233481 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25059838 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 23474741 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 22943820 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15801937 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 20666269 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18789680 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 8608441 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 23861993 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 2531901 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2531901 — Biomarker: ACE
Type: Safety Biomarker (SAF)
Genes: ACE1; CD143
Study 31909554 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 24555998 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23212717 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7624397 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 2647605 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 8388403 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 8388403 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 24351876 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19914369 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 16427526 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17179770 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15123223 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9678714 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31477168 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31477168 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 26555352 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26555352 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26555352 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 16924032 — Biomarker: Beta-secretase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: BACE1; BACE; KIAA1149
Study 15043759 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 31077250 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31077250 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 31077250 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30303905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26049866 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 26049866 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26049866 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22271481 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 19908172 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11896309 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 24045634 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24045634 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 16421350 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16421350 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16421350 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 2655719 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 20582610 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 7776455 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2772366 — Biomarker: PPL mRNA
Type: Predictive Biomarker (PRD)
Genes: PPL; KIAA0568
Study 2772366 — Biomarker: COTL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COTL1; CLP
Study 2772366 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22894574 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9084463 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9084463 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 10856867 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26752109 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 22305273 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 28606085 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24902962 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8080071 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 22766314 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 17719471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17719471 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17719471 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11427774 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9250598 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 31554075 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 31554075 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 31554075 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 31554075 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 26169304 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 24983187 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26479024 — Biomarker: IK mRNA
Type: Predictive Biomarker (PRD)
Genes: IK; RED; RER
Study 20796154 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9856895 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 2171853 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30422243 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 3188824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29570598 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23611893 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 11084060 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 11084060 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2938872 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 2938872 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12443833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8562470 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2292349 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 31039280 — Biomarker: Growth/differentiation factor 15
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 3605188 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 30856112 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 26667262 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 26667262 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 23361101 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10742724 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 26988767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9039154 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 23781269 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23781269 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17716735 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 17378372 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26797266 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 26797266 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24796977 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19040000 — Biomarker: Biliary glycoprotein 1
Type: Safety Biomarker (SAF)
Genes: CEACAM1; BGP; BGP1
Study 19040000 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8629887 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 27169837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10438259 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 10438259 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7586435 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 2147914 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 2147914 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26520398 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 15785163 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15259398 — Biomarker: Auditory mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 15259398 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 26197999 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10323778 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 21432821 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 27568303 — Biomarker: LTB4R mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7