AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 30721948 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 16362784 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 12528093 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19333944 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17961421 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8092235 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27878780 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 29652567 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29652567 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 29652567 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 29652567 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 22124575 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 15774791 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study 11940756 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 2351367 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7014042 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 12352146 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8719015 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 11264555 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 27025337 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24824310 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 20181679 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9860397 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 2527546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3320381 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24297090 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 2809191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6996815 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28330721 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 22580858 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 19013259 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 7736484 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2927990 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2927990 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2927990 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2927990 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31825704 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 17405298 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 15333852 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 21389303 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 17909718 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17909718 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17909718 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17909718 — Biomarker: Human leukocyte antigen DR
Type: Pharmacodynamic Biomarker (PDY)
Study 24258313 — Biomarker: CPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPA1; CPA
Study 24258313 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 24258313 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 18202091 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 14641610 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 10377504 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30646142 — Biomarker: CPD mRNA
Type: Predictive Biomarker (PRD)
Genes: CPD
Study 24715706 — Biomarker: Mothers against decapentaplegic homolog 2
Type: Predictive Biomarker (PRD)
Genes: SMAD2; MADH2; MADR2
Study 15982798 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 30865794 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7545214 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 2523644 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 506802 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19704401 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 11583884 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 16974115 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 10998460 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 10998460 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 1431312 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 1431312 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 31308274 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 26659366 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 24661196 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 17921396 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 16047057 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28096758 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28096758 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 28096758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26086833 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 22107734 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15333855 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 29251282 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 28704263 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18982918 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12887480 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 10100557 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 1746424 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7048879 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10642289 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8446137 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 8446137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29488276 — Biomarker: GLP1R mRNA
Type: Predictive Biomarker (PRD)
Genes: GLP1R
Study 29488276 — Biomarker: TCF7L2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCF7L2; TCF4
Study 8862260 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 1299501 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 27106721 — Biomarker: TPI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPI1; TPI
Study 18418961 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18418961 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 6596055 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27052635 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 37094 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28244706 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 19273709 — Biomarker: MLH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MLH1; COCA2
Study 19273709 — Biomarker: DNA mismatch repair protein MSH2
Type: Predictive Biomarker (PRD)
Genes: MSH2
Study 19273709 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 15054036 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 15054036 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 11964529 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 7637045 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 2515399 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 28319871 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19335078 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 15306157 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 29506034 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 22578899 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22578899 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 17564719 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 11802924 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 2551242 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 26304464 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21270185 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 19922256 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9819168 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 11589838 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 30256548 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 11923558 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 2523769 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 28426885 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 16968715 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10753829 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 27341795 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 12131602 — Biomarker: ZFYVE9 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZFYVE9; MADHIP; SARA; SMADIP
Study 18259972 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 16806442 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 9165581 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 23276888 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16868708 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 9316529 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 3536530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30832692 — Biomarker: RNF128 mRNA
Type: Predictive Biomarker (PRD)
Genes: RNF128
Study 30832692 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 30832692 — Biomarker: CTTN mRNA
Type: Predictive Biomarker (PRD)
Genes: CTTN; EMS1
Study 24818523 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 23911273 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study 23911273 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 22235508 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 22235508 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9141585 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8263640 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26311415 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 2552717 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2552717 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21964491 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28229278 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 21641345 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 10930154 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15830647 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 31362189 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12859533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12859533 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 31425585 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 31425585 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 25015021 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25015021 — Biomarker: HLA-B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: AS
Study 25015021 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 8959891 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8959891 — Biomarker: TNFR1B
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 8959891 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 8959891 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 2991689 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 24885388 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15218043 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 15218043 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 15218043 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 15218043 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 15218043 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 23737646 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 20649936 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16912128 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 16912128 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 28000678 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 28000678 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30202872 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 29043996 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29043996 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29043996 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21305484 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 12057618 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study 899844 — Biomarker: CPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPZ
Study 31972796 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31781387 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 21252245 — Biomarker: GHR mRNA
Type: Predictive Biomarker (PRD)
Genes: GHR
Study 21252245 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 9323798 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 31743110 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 18484552 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 8743522 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30880072 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 18035190 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18035190 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 18035190 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 15094936 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 3101709 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 19689235 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 16202499 — Biomarker: SSB mRNA
Type: Predictive Biomarker (PRD)
Genes: SSB
Study 10709161 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 10709161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3928054 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 30107381 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 22324943 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11334198 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 27198187 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 24515510 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16266408 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 30758406 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 28577362 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 22019891 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 22019891 — Biomarker: COG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: COG2; LDLC
Study 22019891 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 22019891 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22019891 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26364181 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31672172 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21361732 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 8408980 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29114041 — Biomarker: PLA2R1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2R1; CLEC13C
Study 12802741 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27893880 — Biomarker: CA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA3
Study 24267238 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21526923 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 22739141 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 22739141 — Biomarker: Glutamate dehydrogenase
Type: Safety Biomarker (SAF)
Study 22739141 — Biomarker: miR-122
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR122
Study 19846798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19846798 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 9001416 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 8510086 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 15665549 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11839142 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 11839142 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 6650444 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 6650444 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30720850 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24214140 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 29073603 — Biomarker: Angiopoietin-1
Type: Monitoring Biomarker (MOI)
Genes: ANGPT1; KIAA0003
Study 29073603 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 21516008 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18068281 — Biomarker: PAFAH1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study 11180018 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 8264146 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 2984235 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2984235 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 2984235 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP