AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 16817277 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 16817277 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9110115 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 9110115 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1530434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31410465 — Biomarker: XPC mRNA
Type: Predictive Biomarker (PRD)
Genes: XPC; XPCC
Study 31410465 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 18029326 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25134779 — Biomarker: CPE mRNA
Type: Predictive Biomarker (PRD)
Genes: CPE
Study 16924565 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 9129851 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9129851 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23434724 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 10840174 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 17324976 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7805711 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 30980691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23354313 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15562200 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 6991095 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17762738 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 17762738 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31650255 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 31650255 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 11230288 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7968419 — Biomarker: MAP3K14 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP3K14; NIK
Study 7968419 — Biomarker: INVS mRNA
Type: Predictive Biomarker (PRD)
Genes: INVS; INV; NPHP2
Study 2889391 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12750879 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10531155 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 25222001 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study 25222001 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 19651277 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 19651277 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3793849 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 30559106 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 30559106 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 26100557 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 24952855 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 9535416 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11802678 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23212438 — Biomarker: DRD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD4
Study 27927064 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27927064 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27927064 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 8985622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16231757 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7479629 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18984660 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 24189519 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 24189519 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 29093152 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 25019571 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 25019571 — Biomarker: FGFR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR2; BEK; KGFR; KSAM
Study 25019571 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 25019571 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study 25019571 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 25019571 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22110164 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17537764 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 17537764 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 4042306 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18528294 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 18528294 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 9273824 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9273824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28118307 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 24477778 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 24477778 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31939063 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 31939063 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 2676877 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31299919 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 31299919 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 27859427 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 27859427 — Biomarker: DCT mRNA
Type: Predictive Biomarker (PRD)
Genes: DCT; TYRP2
Study 3882739 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 27252245 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22649265 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 23979954 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29481425 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 24495641 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 24495641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21663811 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 19801025 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 9594558 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 9594558 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 9594558 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 9594558 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 31151228 — Biomarker: MTOR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 21414035 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15105027 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15105027 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9589230 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 9589230 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 7990660 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 2660451 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21231888 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 15050696 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 31571150 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 20399288 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study 20399288 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10456461 — Biomarker: REG3A mRNA
Type: Predictive Biomarker (PRD)
Genes: REG3A; HIP; PAP; PAP1
Study 31687396 — Biomarker: CYP1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A1
Study 31687396 — Biomarker: CYP1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1B1
Study 31687396 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 19856194 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9071954 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 16517955 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 29328027 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 29328027 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11728260 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11728260 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11728260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29490302 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29490302 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 18525261 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 18525261 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 18525261 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 15996071 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 29196963 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 29196963 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21749167 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19004198 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 1420996 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 1420996 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 4047702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30575804 — Biomarker: TSHR mRNA
Type: Predictive Biomarker (PRD)
Genes: TSHR; LGR3
Study 30575804 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 20130863 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 567008 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 567008 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 567008 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 30888959 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 26089029 — Biomarker: SLC12A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC12A2; NKCC1
Study 26089029 — Biomarker: SLC12A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC12A1; NKCC2
Study 15611571 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 19996755 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 15701590 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 28385659 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 16581479 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 10770181 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 9395949 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 3602017 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3602017 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 16201856 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 10334412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1697334 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 24158762 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 24158762 — Biomarker: OGG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OGG1; MMH; MUTM; OGH1
Study 24158762 — Biomarker: XPC mRNA
Type: Predictive Biomarker (PRD)
Genes: XPC; XPCC
Study 22920077 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 20133927 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 17478068 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 17478068 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 8595643 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2914082 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 2914082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30582240 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30582240 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 30582240 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 27230861 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 25487930 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 23025735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18728281 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12072043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1841609 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25182045 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25182045 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25182045 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25208464 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 22764762 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19354088 — Biomarker: CORT mRNA
Type: Predictive Biomarker (PRD)
Genes: CORT; UNQ307/PRO350
Study 19354088 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 11356434 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 28992899 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 25882864 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 25882864 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19407805 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26844281 — Biomarker: SOD3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOD3
Study 16750125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9134643 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 8185424 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8185424 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 26291918 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 24881463 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 22237064 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 22237064 — Biomarker: GIPR mRNA
Type: Predictive Biomarker (PRD)
Genes: GIPR
Study 20051257 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 20051257 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 20541286 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 20541286 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 8111802 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 2427858 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20392890 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 20392890 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 1365868 — Biomarker: PDXP mRNA
Type: Predictive Biomarker (PRD)
Genes: PDXP; CIN; PLP; PLPP
Study 25643511 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 15689407 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 8607674 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 18028119 — Biomarker: PHEX mRNA
Type: Predictive Biomarker (PRD)
Genes: PHEX; PEX
Study 15385923 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 11125238 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 11806464 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11806464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29248384 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27640138 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 1958005 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 23013746 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20128370 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 17541390 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17541390 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 825076 — Biomarker: TRH mRNA
Type: Predictive Biomarker (PRD)
Genes: TRH
Study 23904396 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23904396 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23904396 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 17940545 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7996960 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 3414518 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29859917 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 29859917 — Biomarker: ASIC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASIC2; ACCN; ACCN1; BNAC1; MDEG
Study 29859917 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 27792869 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8162750 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28658082 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 25528496 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 25528496 — Biomarker: PIK3R1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3R1; GRB1
Study 25528496 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 8576779 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21521539 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25727486 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 25727486 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18325143 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 11479481 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31178359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24617226 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21835486 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 21835486 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 12531578 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12531578 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10233213 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 30902044 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10780771 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 6837082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27455399 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24966007 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30358417 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 30358417 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 11408002 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 14759446 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 12872052 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)