AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 1345261 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1345261 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29746386 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22035053 — Biomarker: Fatty acid amide hydrolase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: FAAH; FAAH1
Study 16514109 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 11136301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24528667 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23324103 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17385465 — Biomarker: LPO mRNA
Type: Predictive Biomarker (PRD)
Genes: LPO; SAPX
Study 17385465 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15078738 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 11317662 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7932162 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 21150167 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 11118461 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7507638 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21741344 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 19442346 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15257094 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 7012398 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21371993 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23625188 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 17112810 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 9290464 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8100627 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19476474 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 15045033 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 11472705 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 11472705 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7831650 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26514759 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 17447828 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15044817 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 9701178 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28327450 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 14743040 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 29037984 — Biomarker: MAF mRNA
Type: Predictive Biomarker (PRD)
Genes: MAF
Study 23515640 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21247520 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 21247520 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8376687 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 3519092 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30477839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22801094 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 10454438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30606886 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 28893875 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26172564 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 23129746 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 16943110 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 2766658 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 27846092 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 27846092 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 27846092 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20702058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30151230 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25667975 — Biomarker: CADM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CADM1; IGSF4; IGSF4A; NECL2; SYNCAM; TSLC1
Study 25667975 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 2916540 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9577286 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25463415 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 19476983 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 17904983 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11488797 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 11488797 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 30148987 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30148987 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 22170716 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 22170716 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 22170716 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28916992 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 25982649 — Biomarker: DNA repair endonuclease XPF
Type: Predictive Biomarker (PRD)
Genes: ERCC4; ERCC11; XPF
Study 19646048 — Biomarker: NEB mRNA
Type: Predictive Biomarker (PRD)
Genes: NEB
Study 15735202 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 21459902 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16875928 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16875928 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11111968 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 30744298 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22230918 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 22230918 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15455745 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 31764462 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31864178 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31659612 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 19367246 — Biomarker: BLOC1S2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BLOC1S2; BLOS2; CEAP
Study 25910923 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22588852 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19515371 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19515371 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19515371 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31882530 — Biomarker: FXYD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FXYD1; PLM
Study 15649263 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 15649263 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 15649263 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 12420198 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12420198 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30462654 — Biomarker: IVNS1ABP mRNA
Type: Predictive Biomarker (PRD)
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068
Study 24662855 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 23860520 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 20962021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17309130 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 6948504 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6948504 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 30797542 — Biomarker: THBS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: THBS1; TSP; TSP1
Study 25957330 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 23621902 — Biomarker: BOC mRNA
Type: Predictive Biomarker (PRD)
Genes: BOC; UNQ604/PRO1190
Study 17968938 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 14988901 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 26497059 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29504427 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 21239518 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 3917352 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 24553909 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 16258091 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 25663642 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 25663642 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 19190819 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 19190819 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 19190819 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11243949 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 27654143 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 21737232 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21737232 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 14688692 — Biomarker: Heart fatty acid-binding protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FABP3; FABP11; MDGI
Study 31185079 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26853484 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 23764967 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27562361 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22947342 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29317812 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 24662570 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 24662570 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 31786466 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 30535668 — Biomarker: CPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CPB1; CPB; PCPB
Study 29089468 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 29089468 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 25245572 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 25245572 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7832135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2225705 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 25911605 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 25911605 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19717488 — Biomarker: LEP mRNA
Type: Predictive Biomarker (PRD)
Genes: LEP; OB; OBS
Study 19717488 — Biomarker: SOCS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOCS3; CIS3; SSI3
Study 19717488 — Biomarker: PTPN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPN1; PTP1B
Study 19717488 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 19717488 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 27385940 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 1993795 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1993795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22892393 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15956121 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 15956121 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 15956121 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 15956121 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 15956121 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12427152 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 8493299 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 22045595 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 19308365 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 11584153 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 26472406 — Biomarker: DMRTA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DMRTA1; DMO
Study 26472406 — Biomarker: GAL3ST1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAL3ST1; CST
Study 20005750 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 19033012 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16630941 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 1313765 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 1313765 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26541264 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24286443 — Biomarker: MAEA mRNA
Type: Predictive Biomarker (PRD)
Genes: MAEA; EMP; HLC10; PIG5
Study 24286443 — Biomarker: Vascular endothelial cadherin
Type: Safety Biomarker (SAF)
Genes: CDH5
Study 22464260 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 20158897 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 11877267 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 11877267 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 11877267 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 401827 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 28461862 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 24972700 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9111463 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 2901266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21715583 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 16836557 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 12569270 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9114765 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9114765 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 9114765 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 30026341 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 27423645 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 20438395 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 18457472 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 18457472 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 16995893 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 10433851 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 22772170 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20142523 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 17477888 — Biomarker: MT2A mRNA
Type: Predictive Biomarker (PRD)
Genes: MT2A; CES1; MT2
Study 22114787 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 22114787 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 7814812 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 15017527 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15017527 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2877129 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2877129 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 2877129 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 12589153 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30629585 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17966072 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 15564357 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 28854833 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28854833 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 24599010 — Biomarker: OSCAR mRNA
Type: Predictive Biomarker (PRD)
Genes: OSCAR
Study 24599010 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17945470 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 10592355 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10592355 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6273027 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 6273027 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21416219 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21416219 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 15641936 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 7114339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16730732 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16009786 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 16009786 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22245322 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26581683 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 24690159 — Biomarker: APOA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOA5; RAP3; UNQ411/PRO773
Study 18620598 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26920441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25589677 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 16775579 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 19816871 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19816871 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17234504 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2680677 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2680677 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2680677 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9631134 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4