AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 31725459 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 31725531 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 31725531 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31725531 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31726319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31726422 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31726452 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 31727019 — Biomarker: TRAPPC9 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 31727075 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 31727113 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31727136 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31728032 — Biomarker: AIP mRNA
Type: Predictive Biomarker (PRD)
Genes: AIP; XAP2
Study 31728032 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31731085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31731085 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 31732519 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 31732566 — Biomarker: SLC18A2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC18A2; SVMT; VMAT2
Study 31732715 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study 31734214 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31734525 — Biomarker: NPSR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NPSR1; GPR154; GPRA; PGR14
Study 31734820 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31734832 — Biomarker: MDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM2
Study 31734832 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 31734832 — Biomarker: Growth/differentiation factor 15
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 31734899 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31735660 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31735691 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31738181 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31738425 — Biomarker: Tropomyosin-related kinase A
Type: Pharmacodynamic Biomarker (PDY)
Genes: NTRK1; MTC; TRK; TRKA
Study 31738425 — Biomarker: ETV6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV6; TEL; TEL1
Study 31738425 — Biomarker: NTRK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NTRK3; TRKC
Study 31743993 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 31744895 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 31745699 — Biomarker: CYBB mRNA
Type: Predictive Biomarker (PRD)
Genes: CYBB; NOX2
Study 31745699 — Biomarker: NCF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NCF2; NOXA2; P67PHOX
Study 31745703 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 31745703 — Biomarker: FOXP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXP1; HSPC215
Study 31745703 — Biomarker: WWOX mRNA
Type: Predictive Biomarker (PRD)
Genes: WWOX; FOR; SDR41C1; WOX1
Study 31745902 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31748196 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 31748220 — Biomarker: DCLRE1C mRNA
Type: Predictive Biomarker (PRD)
Genes: DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C
Study 31749608 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 31749981 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 31753019 — Biomarker: BTLA mRNA
Type: Predictive Biomarker (PRD)
Genes: BTLA
Study 31753019 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 31753788 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31753788 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31753878 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31755936 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31756405 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 31758517 — Biomarker: PTGS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGS1; COX1
Study 31758773 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31758773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31759037 — Biomarker: LAMB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMB2; LAMS
Study 31760711 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 31760881 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 31760881 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 31761940 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31763491 — Biomarker: OSR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OSR1; ODD
Study 31765809 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31766870 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31767197 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 31767578 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 31768187 — Biomarker: PLG mRNA
Type: Predictive Biomarker (PRD)
Genes: PLG
Study 31768187 — Biomarker: F12 mRNA
Type: Predictive Biomarker (PRD)
Genes: F12
Study 31768261 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31768930 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 31769793 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31770616 — Biomarker: CDKN2B-AS1
Type: Predictive Biomarker (PRD)
Study 31770616 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31770616 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31770616 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 31771603 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 31771603 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31771607 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31771630 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31772121 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31772121 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31772121 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 31773324 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31773439 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31773439 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31774125 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 31774125 — Biomarker: SLC25A18 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A18; GC2
Study 31774125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31774522 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31774688 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 31774957 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31775714 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31776899 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 31777783 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31778074 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 31778074 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 31778074 — Biomarker: ROS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROS1; MCF3; ROS
Study 31778267 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 31778798 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 31780237 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 31781957 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31782492 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31783178 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 31784451 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31785185 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31786971 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31789931 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31790472 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 31790472 — Biomarker: STAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT1
Study 31790472 — Biomarker: STAT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT2
Study 31790472 — Biomarker: IRF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRF1
Study 31790472 — Biomarker: IRF7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRF7
Study 31790472 — Biomarker: Protein disulfide-isomerase A4
Type: Safety Biomarker (SAF)
Genes: PDIA4; ERP70; ERP72
Study 31790472 — Biomarker: FAM72C mRNA
Type: Predictive Biomarker (PRD)
Genes: FAM72C
Study 31790472 — Biomarker: TNFSF10 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF10; APO2L; TRAIL
Study 31790472 — Biomarker: DHX58 mRNA
Type: Predictive Biomarker (PRD)
Genes: DHX58; D11LGP2E; LGP2
Study 31797105 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31798754 — Biomarker: POMC mRNA
Type: Predictive Biomarker (PRD)
Genes: POMC
Study 31799498 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31801624 — Biomarker: TNFRSF9 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF9; CD137; ILA
Study 31801624 — Biomarker: CCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR4; CMKBR4
Study 31804102 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 31805424 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 31806360 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 31806613 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31806722 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 31807036 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 31807567 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study 31809241 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31809243 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31809725 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 31811682 — Biomarker: TFEB mRNA
Type: Predictive Biomarker (PRD)
Genes: TFEB; BHLHE35
Study 31811682 — Biomarker: SQSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SQSTM1; ORCA; OSIL
Study 31811953 — Biomarker: Type I cytoskeletal 18 Keratin
Type: Safety Biomarker (SAF)
Genes: KRT18; CYK18; PIG46
Study 31813938 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 31815579 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 31815739 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31815739 — Biomarker: CXCR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR3; GPR9
Study 31816924 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study 31817795 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 31817795 — Biomarker: FCGR3A
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16a; FcgammaRIIIa; FcGRIIIA
Study 31819193 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 31819404 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 31819632 — Biomarker: ASL mRNA
Type: Predictive Biomarker (PRD)
Genes: ASL
Study 31820157 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 31820199 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31820981 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 31821339 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31824147 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31824147 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 31824943 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31825714 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31826340 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 31827323 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 31827323 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 31828307 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 31831151 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 31831560 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 31833973 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 31834365 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 31834916 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 31835495 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 31835495 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 31836927 — Biomarker: SLC22A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A2; OCT2
Study 31837149 — Biomarker: RARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RARS1; RARS
Study 31838007 — Biomarker: Tropomyosin-related kinase A
Type: Pharmacodynamic Biomarker (PDY)
Genes: NTRK1; MTC; TRK; TRKA
Study 31838007 — Biomarker: NTRK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NTRK2; TRKB
Study 31838007 — Biomarker: NTRK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NTRK3; TRKC
Study 31838015 — Biomarker: ROS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROS1; MCF3; ROS
Study 31838512 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31838939 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 31840425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31840425 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 31841594 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 31841594 — Biomarker: 2-hydroxyglutarate
Type: Pharmacodynamic Biomarker (PDY)
Study 31842931 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 31842963 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 31843273 — Biomarker: EZH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EZH2; KMT6
Study 31845423 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 31849164 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31849164 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 31849202 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31849202 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 31849542 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 31851518 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 31851732 — Biomarker: ZDHHC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZDHHC2; REAM; REC; ZNF372
Study 31852810 — Biomarker: ARSA mRNA
Type: Predictive Biomarker (PRD)
Genes: ARSA
Study 31852810 — Biomarker: Dihydrothymine dehydrogenase
Type: Safety Biomarker (SAF)
Genes: DPYD
Study 31852810 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 31852810 — Biomarker: Hydroxyphenylpyruvate dioxygenase
Type: Safety Biomarker (SAF)
Genes: HPD; PPD
Study 31852810 — Biomarker: MYBPC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYBPC3
Study 31852810 — Biomarker: Interleukin 7 receptor alpha
Type: Pharmacodynamic Biomarker (PDY)
Genes: IL7R
Study 31852810 — Biomarker: HSD17B4 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSD17B4; EDH17B4; SDR8C1
Study 31852810 — Biomarker: PRODH mRNA
Type: Predictive Biomarker (PRD)
Genes: PRODH; PIG6; POX2; PRODH2
Study 31852847 — Biomarker: KLF15 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLF15; KKLF
Study 31852847 — Biomarker: MEF2C mRNA
Type: Predictive Biomarker (PRD)
Genes: MEF2C
Study 31852847 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 31853265 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 31855231 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 31855577 — Biomarker: USO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: USO1; VDP
Study 31856860 — Biomarker: CEBPB mRNA
Type: Predictive Biomarker (PRD)
Genes: CEBPB; TCF5; PP9092
Study 31858293 — Biomarker: TSPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPO; BZRP; MBR
Study 31858327 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31858403 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 31860140 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study 31862084 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 31862084 — Biomarker: SULT1A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SULT1A3; STM
Study 31863283 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 31863305 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 31865391 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 31865391 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 31865771 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 31865797 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 31866281 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 31867125 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 31867125 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 31867125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31867437 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31869417 — Biomarker: KIR2DL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: KIR2DL3; CD158B2; KIRCL23; NKAT2
Study 31869417 — Biomarker: KIR3DL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KIR3DL1; CD158E; NKAT3; NKB1
Study 31870883 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 31874111 — Biomarker: LRBA mRNA
Type: Predictive Biomarker (PRD)
Genes: LRBA; BGL; CDC4L; LBA
Study 31874111 — Biomarker: IKBKG mRNA
Type: Predictive Biomarker (PRD)
Genes: IKBKG; FIP3; NEMO
Study 31874111 — Biomarker: SAMD9L mRNA
Type: Predictive Biomarker (PRD)
Genes: SAMD9L; C7orf6; DRIF2; KIAA2005; UEF
Study 31874111 — Biomarker: SAMHD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAMHD1; MOP5
Study 31874111 — Biomarker: TREX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TREX1
Study 31875915 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 31875915 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31875931 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 31876124 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 31876911 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 31876927 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 31879782 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31879814 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 31880950 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 31881853 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study 31881853 — Biomarker: KIAA1549 mRNA
Type: Predictive Biomarker (PRD)
Genes: KIAA1549
Study 31882281 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 31882377 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 31882377 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28