AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23003916 — Biomarker: MCF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCF2; DBL
Study 21300712 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8404115 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2957569 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28306636 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15888038 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12218418 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30284018 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 24615047 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 19650674 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 29379143 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15860237 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 15860237 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 19939373 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 18540734 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15846228 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 23706048 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 20102772 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20102772 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9495222 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8053737 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8053737 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 19284663 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27622998 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 19361872 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 18287162 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8403911 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 20449532 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 6137327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6137327 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 6137327 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 24769332 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 21701082 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 21701082 — Biomarker: PTPRC mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRC; CD45
Study 21701082 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 17470830 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11510062 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 9669006 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 26420199 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 17208334 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 12460519 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7700763 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2199618 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 276963 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31112273 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 31112273 — Biomarker: FCGR3B
Type: Predictive Biomarker (PRD)
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 31112273 — Biomarker: IL1RN mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RN; IL1F3; IL1RA
Study 31112273 — Biomarker: T-cell specific protein RANTES
Type: Safety Biomarker (SAF)
Genes: CCL5; D17S136E; SCYA5
Study 31112273 — Biomarker: C-X-C motif chemokine 5
Type: Safety Biomarker (SAF)
Genes: CXCL5; ENA78; SCYB5
Study 31112273 — Biomarker: CCR2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCR2; CMKBR2
Study 31112273 — Biomarker: CCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR4; CMKBR4
Study 31112273 — Biomarker: CCR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 31112273 — Biomarker: CXCR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR2; IL8RB
Study 31112273 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 31112273 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 24337619 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 23891702 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 23891702 — Biomarker: POMC mRNA
Type: Predictive Biomarker (PRD)
Genes: POMC
Study 23891702 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23891702 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 8334344 — Biomarker: NELFE mRNA
Type: Predictive Biomarker (PRD)
Genes: NELFE; RD; RDBP
Study 28470563 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26114234 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 20838991 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 15596636 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 15596636 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 11387278 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 11387278 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11387278 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 30993934 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 28422346 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 28422346 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 28422346 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16510122 — Biomarker: XRCC1
Type: Safety Biomarker (SAF)
Genes: RCC
Study 16510122 — Biomarker: DNA excision repair protein ERCC-1
Type: Predictive Biomarker (PRD)
Genes: ERCC1
Study 16510122 — Biomarker: XRCC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: XRCC3
Study 3085261 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 3085261 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 11558795 — Biomarker: HLA-DQB1
Type: Safety Biomarker (SAF)
Genes: IDDM1; CELIAC1
Study 29986023 — Biomarker: CYBB mRNA
Type: Predictive Biomarker (PRD)
Genes: CYBB; NOX2
Study 29986023 — Biomarker: Hypoxia-inducible factor 1-alpha
Type: Predictive Biomarker (PRD)
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 29986023 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 20950476 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 12419297 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 12419297 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 17526862 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 26372487 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 16875796 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 31450964 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23226426 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 23226426 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 23226426 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 17539738 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 15610365 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 10845823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3545686 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22803404 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 22803404 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 18036290 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 18036290 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 28209624 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23609792 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 23609792 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 9256120 — Biomarker: PGR mRNA
Type: Predictive Biomarker (PRD)
Genes: PGR; NR3C3
Study 30282375 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 16408674 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29020174 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 29020174 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 26194691 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 26194691 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26194691 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 15289960 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 8088691 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26844764 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9369422 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 9369422 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 9369422 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 8239585 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 7967425 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 25792808 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25792808 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 17084257 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17084257 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 9741608 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 3132853 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20175801 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 31155698 — Biomarker: OPRM1
Type: Safety Biomarker (SAF)
Genes: MOR1; MOP
Study 11386927 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 7837160 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 11011341 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20884464 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 18447225 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16390570 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 11340886 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30809967 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 30809967 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 30303516 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 30303516 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 30303516 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27650287 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 20153570 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11954880 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 2113611 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 12620440 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 12620440 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9878944 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9878944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1902264 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 25998198 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 25998198 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 23906374 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 21817188 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 15780528 — Biomarker: TERT mRNA
Type: Predictive Biomarker (PRD)
Genes: TERT; EST2; TCS1; TRT
Study 15780528 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 31525702 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study 24494279 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 21555816 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 21555816 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 17113564 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 8583482 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2698570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25266246 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25266246 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 16110353 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 16110353 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 12520750 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 2506751 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31833569 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2757958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31479045 — Biomarker: NR3C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR3C2; MCR; MLR
Study 31574097 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26204844 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17394957 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 28879445 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 19415120 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 29128692 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 21814138 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 15488341 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11681631 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 7524313 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 7524313 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 31758375 — Biomarker: TLR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR3
Study 28954802 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 16434457 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 14688031 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 11768323 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 9390976 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9390976 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 27025240 — Biomarker: MKRN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MKRN3; D15S9; RNF63; ZNF127
Study 22980293 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 11527119 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 11527119 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26407272 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 25211490 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 25211490 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 25211490 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 25211490 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 20465648 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 18022044 — Biomarker: SCAMP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SCAMP1; SCAMP
Study 15983242 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12551867 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 24287601 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24287601 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 22169459 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16170758 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 9920062 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 9920062 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 7589392 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2123791 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 2123791 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 31288859 — Biomarker: MME mRNA
Type: Predictive Biomarker (PRD)
Genes: MME; EPN
Study 25674699 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25374269 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 1827007 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1827007 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 27623234 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 27623234 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 27623234 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27623234 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 9860093 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study 25881456 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21335417 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 21335417 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 18570223 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 15593039 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15593039 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2505631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25213566 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 20298497 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 28726510 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 18503840 — Biomarker: CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR1; C3BR
Study 18503840 — Biomarker: CR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR2; C3DR
Study 12748498 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12748498 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 10921707 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8