AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 23438483 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 8610312 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 30678193 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 30678193 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30678193 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 28361746 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28361746 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 28361746 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 16461817 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 9447368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29630549 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26562046 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24068048 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 21417560 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 21417560 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21417560 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 21417560 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16988930 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 16988930 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 31245842 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 16827869 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 10921706 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 11159252 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 8297542 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 8297542 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 3443128 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31246109 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16129715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 22542709 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 16326006 — Biomarker: NRG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study 25565669 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 25565669 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 23559222 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23559222 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 15901043 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 15901043 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 15901043 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12687534 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 25316469 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 17278988 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 17278988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11863247 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31912391 — Biomarker: LSS mRNA
Type: Predictive Biomarker (PRD)
Genes: LSS; OSC
Study 29482525 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 17012900 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 10757582 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 3532763 — Biomarker: Serum antibody concentration
Type: Surrogate Endpoint (SUR)
Study 29593013 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 29593013 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 29593013 — Biomarker: APOB mRNA
Type: Predictive Biomarker (PRD)
Genes: APOB
Study 29593013 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 27538423 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27538423 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 22717177 — Biomarker: NKRF mRNA
Type: Predictive Biomarker (PRD)
Genes: NKRF; ITBA4; NRF
Study 20298928 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 25663125 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 18638266 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 17380846 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 17380846 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10809917 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 10809917 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 8646827 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 6500225 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19366848 — Biomarker: NES mRNA
Type: Predictive Biomarker (PRD)
Genes: NES; Nbla00170
Study 26002840 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23344779 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 11672921 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 27212005 — Biomarker: TRAPPC9 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 22302136 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20201949 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 9376241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27194308 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 22974788 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 22974788 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26778544 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24266855 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 3516511 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30304013 — Biomarker: LRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LRP1; A2MR; APR
Study 12587093 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 14724827 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 1426218 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 2861738 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 10780315 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 10780315 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 8842353 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15951466 — Biomarker: ABCC8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC8; HRINS; SUR; SUR1
Study 24371021 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 17700217 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15334764 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 28329386 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 12658059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12658059 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 9024279 — Biomarker: CRH mRNA
Type: Predictive Biomarker (PRD)
Genes: CRH
Study 17496226 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 26549402 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 26549402 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 6185209 — Biomarker: BLM mRNA
Type: Predictive Biomarker (PRD)
Genes: BLM; RECQ2; RECQL3
Study 27159993 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 20005375 — Biomarker: Prognostic nutrition index
Type: Safety Biomarker (SAF)
Study 2353183 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 31727676 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 25927321 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 16595614 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14609606 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 14609606 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26284918 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23471469 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 18211600 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 17012138 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 10740141 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 30043449 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 15588161 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15588161 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 15588161 — Biomarker: IL1B
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL1F2; IL-1B; IL1-BETA
Study 2297349 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 7002197 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24007456 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 24007456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 9402071 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 22946930 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 1334819 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 2183665 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 2183665 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 25173538 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15099990 — Biomarker: DHFR mRNA
Type: Predictive Biomarker (PRD)
Genes: DHFR
Study 15099990 — Biomarker: DHPS mRNA
Type: Predictive Biomarker (PRD)
Genes: DHPS; DS
Study 22840286 — Biomarker: POMC mRNA
Type: Predictive Biomarker (PRD)
Genes: POMC
Study 22840286 — Biomarker: CARTPT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CARTPT; CART
Study 22840286 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 22840286 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22840286 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 21294631 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 19321562 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11592726 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 27765800 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18327581 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 25385260 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 15223858 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 23185261 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28636851 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 26289514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20374312 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 20374312 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 9612832 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 25879008 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20110026 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 17275927 — Biomarker: CARD16 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARD16; COP; COP1
Study 15533270 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 9491823 — Biomarker: ITGB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB2; CD18; MFI7
Study 31320177 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 31320177 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26287302 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23453104 — Biomarker: SERPINA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 23453104 — Biomarker: APEX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 23453104 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16143706 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 1822966 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 24321717 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 1508060 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 30557377 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 27803393 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 24671507 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 24671507 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 24671507 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 31084684 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 23927461 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15613919 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 3098194 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 3098194 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 15877999 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 6507951 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 26948466 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20592128 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 18801505 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 15695129 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15695129 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12061948 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 27424812 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 25122422 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 25122422 — Biomarker: ALK
Type: Predictive Biomarker (PRD)
Genes: CD246; ALK1
Study 20122035 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 20122035 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 26988693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26988693 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23828292 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 23828292 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 19118696 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 19118696 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 16409564 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11480712 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 30184103 — Biomarker: FST mRNA
Type: Predictive Biomarker (PRD)
Genes: FST
Study 24108668 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 17315118 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8436151 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20231198 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15766995 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15766995 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 1961962 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6118333 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6118333 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study 21851876 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 21851876 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21851876 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 19318693 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 19263563 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 16911680 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 29174316 — Biomarker: TLR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR3
Study 23033863 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 17353866 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 2851172 — Biomarker: TIMM8A mRNA
Type: Predictive Biomarker (PRD)
Genes: TIMM8A; DDP; DDP1; TIM8A
Study 3376710 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 30442868 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23153742 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 23153742 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23153742 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 20667439 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 20667439 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 18986531 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 28509725 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 23336628 — Biomarker: DCC mRNA
Type: Predictive Biomarker (PRD)
Genes: DCC; IGDCC1
Study 20359723 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 26295664 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 12923404 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 12923404 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 31902311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29788230 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29788230 — Biomarker: ZEB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZEB1; AREB6; TCF8
Study 29788230 — Biomarker: NOTCH3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOTCH3
Study 16239629 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16980814 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 16980814 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 12562461 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 23557025 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 23557025 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 12539808 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 12539808 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 12539808 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24371832 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 24371832 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 24371832 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24371832 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 24371832 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 20056852 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 20056852 — Biomarker: PGC mRNA
Type: Predictive Biomarker (PRD)
Genes: PGC