AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT00134381 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study NCT01158222 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00313196 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00313196 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study NCT02654236 — Biomarker: NR1H4 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT00377559 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01762267 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00702494 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02307799 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT01655381 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01633346 — Biomarker: STAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT1
Study NCT01633346 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study NCT01633346 — Biomarker: STAT5A mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT5A; STAT5
Study NCT01633346 — Biomarker: STAT5B mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT5B
Study NCT03418558 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05188352 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT04655911 — Biomarker: NAGLU mRNA
Type: Predictive Biomarker (PRD)
Genes: NAGLU; UFHSD1
Study NCT02178475 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT03397992 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04122833 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04122833 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT04406636 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study NCT01863134 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study NCT00219128 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02386943 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT00601861 — Biomarker: IL21
Type: Predictive Biomarker (PRD)
Genes: Za11; IL-21
Study NCT01007695 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01007695 — Biomarker: Histone acetylation
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01007695 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT01007695 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study NCT03724201 — Biomarker: UCHL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCHL1
Study NCT03724201 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT02224365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01826500 — Biomarker: ITIH5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITIH5; KIAA1953; PP14776; UNQ311/PRO354
Study NCT03135678 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02213939 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04626960 — Biomarker: ADRB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB3; ADRB3R; B3AR
Study NCT04626960 — Biomarker: ROCK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROCK2; KIAA0619
Study NCT00819845 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study NCT00819845 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study NCT00819845 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT04328129 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT02388997 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT02730416 — Biomarker: EN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EN1
Study NCT03619395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02509507 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT00775281 — Biomarker: TACR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TACR1; NK1R; TAC1R
Study NCT03536039 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00004864 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study NCT01449773 — Biomarker: NPC1L1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NPC1L1
Study NCT01449773 — Biomarker: DGAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DGAT1; AGRP1; DGAT
Study NCT01449773 — Biomarker: ACAT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAT2; ACTL
Study NCT01449773 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study NCT03306888 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study NCT04510935 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03281551 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT04500236 — Biomarker: Neurofilament light polypeptide
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: NEFL; NF68; NFL
Study NCT04500236 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT00933244 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03291613 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03738150 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT03738150 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study NCT01749891 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT04216082 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT04644432 — Biomarker: RHOH mRNA
Type: Predictive Biomarker (PRD)
Genes: RHOH; ARHH; TTF
Study NCT02762721 — Biomarker: FGFR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT04049240 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00483925 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00483925 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01470404 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study NCT04000334 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01540578 — Biomarker: SH3PXD2A mRNA
Type: Predictive Biomarker (PRD)
Genes: SH3PXD2A; FISH; KIAA0418; SH3MD1; TKS5
Study NCT04913428 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT02098161 — Biomarker: DIABLO mRNA
Type: Predictive Biomarker (PRD)
Genes: DIABLO; SMAC
Study NCT00913393 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT01920152 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT01156168 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT00907920 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT04357964 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study NCT04357964 — Biomarker: UCP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP1; SLC25A7; UCP
Study NCT04035096 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT00533858 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01995552 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01665989 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00607854 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT01812369 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study NCT03926312 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04251975 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04299763 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04299763 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study NCT02014415 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT00646204 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03721809 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study NCT02611167 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT03692689 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04341480 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT02063997 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study NCT00797992 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01558882 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT01558882 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT02396953 — Biomarker: PTPRF mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRF; LAR
Study NCT02177409 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01968577 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study NCT03622177 — Biomarker: IL33 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL33; C9orf26; IL1F11; NFHEV
Study NCT03683134 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02428920 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01437813 — Biomarker: Zinc finger protein GLI1
Type: Predictive Biomarker (PRD)
Genes: GLI1; GLI
Study NCT01470469 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study NCT01470469 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03535480 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT03167489 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02396758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00868673 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00482768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT02814097 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study NCT00498433 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study NCT04852510 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study NCT03342170 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study NCT01835249 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03493854 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03493854 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00170989 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00621829 — Biomarker: ALOX5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALOX5; LOG5
Study NCT02827500 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01989702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01846559 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT04615325 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT02748577 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study NCT02153905 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT01546116 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT03443232 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study NCT01237652 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03101475 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT02017132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03829735 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT05556213 — Biomarker: miR-125b
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT04563247 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT02547220 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT02551562 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT00638703 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study NCT00869622 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03424525 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01148953 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study NCT02796807 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03779217 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT02199431 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT02199431 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT04075409 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study NCT01414556 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT00702130 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT01018459 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study NCT01018459 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT04225039 — Biomarker: TNFRSF18 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF18; AITR; GITR; UNQ319/PRO364
Study NCT04225039 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00559962 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study NCT03497780 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT03497780 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study NCT01831310 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study NCT01831310 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT01831310 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT03985371 — Biomarker: EED mRNA
Type: Predictive Biomarker (PRD)
Genes: EED
Study NCT02458443 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00584467 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study NCT00703105 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT00703105 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study NCT00703105 — Biomarker: WT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WT1
Study NCT02320344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00677495 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study NCT00325806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00325806 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT03693339 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT01486563 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study NCT01486563 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study NCT03279276 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT04115358 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT01205165 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study NCT01205165 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT04032756 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT00003694 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT00003694 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT04435327 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT04182581 — Biomarker: TNFRSF17 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF17; BCM; BCMA
Study NCT04182581 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT04520945 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT00799617 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study NCT00799617 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT01356823 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT03837795 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study NCT04916834 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT04570683 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01513252 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03061539 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study NCT01516879 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00448266 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study NCT02684864 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study NCT01013415 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT01013415 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT02737202 — Biomarker: TSC2
Type: Predictive Biomarker (PRD)
Genes: tuberin; LAM; PPP1R160
Study NCT00004031 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT00437034 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT04143412 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT00513695 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT03717038 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00249301 — Biomarker: Aurora kinase A
Type: Predictive Biomarker (PRD)
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT04311398 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT04247126 — Biomarker: CDK7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK7; CAK; CAK1; CDKN7; MO15; STK1
Study NCT04247126 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT04247126 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03484962 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study NCT02205541 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study NCT04313894 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT03305471 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00519714 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT00519714 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study NCT00519714 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00519714 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT01929564 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04048798 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT02414555 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01152060 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT00936078 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT01384058 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT03974100 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT03337724 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study NCT03337724 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study NCT03337724 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study NCT03337724 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03337724 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT03337724 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT03337724 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00773097 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study NCT03023696 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4