AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 29886499 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 28034693 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 20533214 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15080373 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 15080373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24061999 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 31227466 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 31227466 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 31227466 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 11696471 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 11696471 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 11696471 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 2467116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27179830 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 27179830 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 21838789 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 10493456 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 10493456 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 1717782 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6635104 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30817466 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 25701337 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 25701337 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 30885800 — Biomarker: ST8SIA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ST8SIA4; PST; PST1; SIAT8D
Study 19647859 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 7706702 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2689970 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 2689970 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 2689970 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 2689970 — Biomarker: TP53INP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TP53INP1; P53DINP1; SIP
Study 23550251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19928397 — Biomarker: Auditory steady-state response
Type: Pharmacodynamic Biomarker (PDY)
Study 16700202 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 29511994 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2442552 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2442552 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27113628 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 24845171 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 1482268 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 24273568 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 24273568 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 24273568 — Biomarker: C-X-C motif chemokine 11
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 20693157 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 15842142 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 15842142 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 15842142 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 15842142 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 30295335 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 27022111 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 17631800 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 17631800 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 17631800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 21179917 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 8534483 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 1810682 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 1810682 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 29507752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11196521 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 7916401 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 25600221 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 25600221 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15213896 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 16677162 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 16677162 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 9091555 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 7037661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30782917 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 24903197 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 17301557 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30993344 — Biomarker: Bacteroidetes phylum
Type: Safety Biomarker (SAF)
Study 11061574 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 9352161 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study 3709018 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 29027324 — Biomarker: miR-132
Type: Pharmacodynamic Biomarker (PDY)
Genes: MIR132
Study 20442540 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 12600228 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 12600228 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 12600228 — Biomarker: KIT
Type: Predictive Biomarker (PRD)
Genes: CD117; SCFR; C-Kit
Study 1718369 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 8887592 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1291567 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 31637821 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17621459 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 30743107 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 30743107 — Biomarker: PGR mRNA
Type: Predictive Biomarker (PRD)
Genes: PGR; NR3C3
Study 30743107 — Biomarker: CYP19A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 30743107 — Biomarker: SLC35A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC35A1
Study 30743107 — Biomarker: APOB mRNA
Type: Predictive Biomarker (PRD)
Genes: APOB
Study 30743107 — Biomarker: AQP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP3
Study 30743107 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 30743107 — Biomarker: HK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: HK2
Study 30743107 — Biomarker: CCN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 30743107 — Biomarker: IFNE mRNA
Type: Predictive Biomarker (PRD)
Genes: IFNE; IFNE1; UNQ360/PRO655
Study 30743107 — Biomarker: FGF9 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF9
Study 23945716 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 23945716 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 1422319 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 20163570 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 16314787 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 15986749 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 30242334 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 25572630 — Biomarker: CYP24A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP24A1; CYP24
Study 25572630 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 19910359 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 29341850 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 29341850 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19646775 — Biomarker: Plasma DNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 15641938 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 12211491 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 7852748 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 30036394 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 27366745 — Biomarker: miR-223
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR223
Study 27366745 — Biomarker: miR-150
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR150
Study 27366745 — Biomarker: miR-96
Type: Safety Biomarker (SAF)
Genes: MIR96
Study 2146812 — Biomarker: CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR1; C3BR
Study 31606655 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 31606655 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17920548 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 17920548 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 8861661 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 1293307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 6538006 — Biomarker: Homovanillic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 31308344 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 31308344 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 31308344 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 31308344 — Biomarker: Th2 cell
Type: Safety Biomarker (SAF)
Study 27174596 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 27174596 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 8707473 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 29287665 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 27437769 — Biomarker: ABCC4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCC4; MOATB; MRP4
Study 27437769 — Biomarker: GRK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRK3; ADRBK2; BARK2
Study 27437769 — Biomarker: UHRF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: UHRF1; ICBP90; NP95; RNF106
Study 27437769 — Biomarker: ZNF551 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZNF551; KOX23
Study 15809460 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26232169 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 26232169 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 26232169 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26232169 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 26232169 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 26232169 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 19404671 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 16490804 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 8446653 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19763023 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 11265775 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 11265775 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 11265775 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 30095791 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 26687339 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26687339 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 26687339 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 26687339 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20590479 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 10494774 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 1672530 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 19100282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 15811058 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 7503003 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 27855441 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 24445291 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 23559286 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16436127 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 23067919 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 23067919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 7527406 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 28888275 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18849613 — Biomarker: CCR3 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CCR3; CMKBR3
Study 18849613 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 18849613 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 17156425 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 17156425 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 29443867 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27242317 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18568272 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 15759527 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 31870925 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 31870925 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 9747829 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 7843870 — Biomarker: SEMG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEMG1; SEMG
Study 24126713 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 16850457 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 16146902 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 11703958 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 9394096 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 31744959 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 31744959 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 26900641 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 2232659 — Biomarker: Plasma testosterone level
Type: Surrogate Endpoint (SUR)
Study 17875971 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23403073 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 18156664 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 8129764 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 28251555 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 15119162 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 28512158 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 18322413 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 10756221 — Biomarker: CAMP mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMP; CAP18; FALL39; HSD26
Study 10756221 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 10756221 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 8334749 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 27283375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 11434164 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 19473593 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 19473593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 26049689 — Biomarker: Solute carrier family 29 member 1
Type: Predictive Biomarker (PRD)
Genes: SLC29A1; ENT1
Study 28639369 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 28639369 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 28639369 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 23249532 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 21481147 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 19500141 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 27647856 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 26084693 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 26084693 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 19185645 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 19185645 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 19185645 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 19185645 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 14692989 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 3526627 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 20531232 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study 15955241 — Biomarker: SERPINH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINH1; CBP1; CBP2; HSP47; SERPINH2; PIG14
Study 10598520 — Biomarker: EHF mRNA
Type: Predictive Biomarker (PRD)
Genes: EHF; ESE3; ESE3B; ESEJ
Study 25054387 — Biomarker: SERPINA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA2; ARGS; ATR; PIL; SERPINA2P
Study 15795426 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 15795426 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 11959049 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 29046301 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 17521544 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 14725484 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 14725484 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 8124802 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 8124802 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 31566680 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31566680 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 20971747 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 20971747 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 3117403 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 29424469 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 20842418 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)